Professor Juan M. Irache – Kudos: Growing the influence of research

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Berberine-Loaded Liposomes for the Treatment of Leishmania infantum-Infected BALB/c Mice

Article • Pharmaceutics, September 2020, MDPI AG

Professor Juan M. Irache
Protective Passive Immunity in Escherichia coli ETEC-Challenged Neonatal Mice Conferred by Orally Immunized Dams with Nanoparticles Containing Homologous Outer Membrane Vesicles

Article • Vaccines, June 2020, MDPI AG

Professor Juan M. Irache
Zein-based nanoparticles for the oral delivery of insulin

Article • Drug Delivery and Translational Research, June 2020, Springer Science + Business Media

Professor Juan M. Irache
Zein nanoparticles improve the oral bioavailability of resveratrol in humans

Article • Journal of Drug Delivery Science and Technology, June 2020, Elsevier

Professor Juan M. Irache
Protein-based nanoparticles for drug delivery purposes

Article • International Journal of Pharmaceutics, May 2020, Elsevier

Professor Juan M. Irache
Intranasal delivery system of bacterial antigen using thermosensitive hydrogels based on a Pluronic-Gantrez conjugate

Article • International Journal of Pharmaceutics, April 2020, Elsevier

Professor Juan M. Irache
Preparación, radiomarcaje con 99mTc y 67Ga y estudios de biodistribución de nanopartículas de albúmina con recubrimientos poliméricos

Article • Revista Española de Medicina Nuclear e Imagen Molecular, March 2020, Elsevier

Professor Juan M. Irache
In vivo efficacy of bevacizumab-loaded albumin nanoparticles in the treatment of colorectal cancer

Article • Drug Delivery and Translational Research, February 2020, Springer Science + Business Media

Professor Juan M. Irache
Encapsulation of probiotics in soybean protein-based microparticles preserves viable cell concentration in foods all along the production and storage processes

Article • Journal of Microencapsulation, January 2020, Taylor & Francis

Professor Juan M. Irache
Oral Immunogenicity in Mice and Sows of Enterotoxigenic Escherichia Coli Outer-Membrane Vesicles Incorporated into Zein-Based Nanoparticles

Article • Vaccines, December 2019, MDPI AG

Professor Juan M. Irache
Modulation of the fate of zein nanoparticles by their coating with a Gantrez® AN-thiamine polymer conjugate

Article • December 2019, Elsevier

Professor Juan M. Irache
Evaluation of Skin Permeation and Retention of Topical Dapsone in Murine Cutaneous Leishmaniasis Lesions

Article • Pharmaceutics, November 2019, MDPI AG

Professor Juan M. Irache
Dissolving Microneedles for Intradermal Vaccination against Shigellosis

Article • Vaccines, October 2019, MDPI AG

Professor Juan M. Irache
Casein nanoparticles in combination with 2-hydroxypropyl-β-cyclodextrin improves the oral bioavailability of quercetin

Article • International Journal of Pharmaceutics, October 2019, Elsevier

Professor Juan M. Irache
Nanoparticles from Gantrez® AN-poly(ethylene glycol) conjugates as carriers for oral delivery of docetaxel

Article • International Journal of Pharmaceutics, September 2019, Elsevier

Professor Juan M. Irache
In vivo effect of bevacizumab-loaded albumin nanoparticles in the treatment of corneal neovascularization

Article • Experimental Eye Research, August 2019, Elsevier

Professor Juan M. Irache
Mannosylated Nanoparticles for Oral Immunotherapy in a Murine Model of Peanut Allergy

Article • Journal of Pharmaceutical Sciences, July 2019, Elsevier

Professor Juan M. Irache
In vitro characterization of new stabilizing albumin nanoparticles as a potential topical drug delivery system in the treatment of corneal neovascularization (CNV)

Article • Journal of Drug Delivery Science and Technology, April 2019, Elsevier

Professor Juan M. Irache
The effect of thiamine-coating nanoparticles on their biodistribution and fate following oral administration

Article • European Journal of Pharmaceutical Sciences, February 2019, Elsevier

Professor Juan M. Irache
Understanding the basis of transcutaneous vaccine delivery

Article • Therapeutic Delivery, January 2019, Future Science

Professor Juan M. Irache
Towards a subunit vaccine from a Shigella flexneri ΔtolR mutant

Article • Vaccine, November 2018, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Combination of paromomycin plus human anti-TNF-α antibodies to control the local inflammatory response in BALB/ mice with cutaneous leishmaniasis lesions

Article • Journal of Dermatological Science, October 2018, Elsevier

Professor Juan M. Irache
Increased Oral Bioavailability of Resveratrol by Its Encapsulation in Casein Nanoparticles

Article • International Journal of Molecular Sciences, September 2018, MDPI AG

Professor Juan M. Irache
Cyclodextrin-grafted poly(anhydride) nanoparticles for oral glibenclamide administration. In vivo evaluation using C. elegans

Article • International Journal of Pharmaceutics, August 2018, Elsevier

Professor Juan M. Irache
Pegylated poly(anhydride) nanoparticles for oral delivery of docetaxel

Article • European Journal of Pharmaceutical Sciences, June 2018, Elsevier

Professor Juan M. Irache
Pegylated nanoparticles for the oral delivery of nimodipine: Pharmacokinetics and effect on the anxiety and cognition in mice

Article • International Journal of Pharmaceutics, May 2018, Elsevier

Professor Juan M. Irache
Evaluation of nanoparticles as oral vehicles for immunotherapy against experimental peanut allergy

Article • International Journal of Biological Macromolecules, April 2018, Elsevier

Professor Juan M. Irache
Human serum albumin nanoparticles for ocular delivery of bevacizumab

Article • International Journal of Pharmaceutics, April 2018, Elsevier

Professor Juan M. Irache
Coencapsulation of cyclodextrins into poly(anhydride) nanoparticles to improve the oral administration of glibenclamide. A screening on C. elegans

Article • Colloids and Surfaces B Biointerfaces, March 2018, Elsevier

Professor Juan M. Irache
Evaluation of the treatment with resveratrol-loaded nanoparticles in intestinal injury model caused by ischemia and reperfusion

Article • Toxicology, March 2018, Elsevier

Professor Juan M. Irache
Poly(anhydride) nanoparticles containing cashew nut proteins can induce a strong Th1 and Treg immune response after oral administration

Article • European Journal of Pharmaceutics and Biopharmaceutics, February 2018, Elsevier

Professor Juan M. Irache
Soybean protein-based microparticles for oral delivery of probiotics with improved stability during storage and gut resistance

Article • Food Chemistry, January 2018, Elsevier

Professor Juan M. Irache
Maternal Vaccination. Immunization of Sows during Pregnancy against ETEC Infections

Article • Vaccines, December 2017, MDPI AG

Professor Juan M. Irache, Professor Carlos Gamazo
Special Issue: Pharmaceutics and Drug Delivery in Spain

Article • Journal of Drug Delivery Science and Technology, December 2017, Elsevier

Professor Maria J Blanco-Prieto, Professor Juan M. Irache
A combination of nanosystems for the delivery of cancer chemoimmunotherapeutic combinations: 1-Methyltryptophan nanocrystals and paclitaxel nanoparticles

Article • Pharmacological Research, December 2017, Elsevier

Professor Juan M. Irache
Optimization and evaluation of zein nanoparticles to improve the oral delivery of glibenclamide. In vivo study using C. elegans

Article • European Journal of Pharmaceutics and Biopharmaceutics, December 2017, Elsevier

Professor Juan M. Irache
Oral immunotherapy using polymeric nanoparticles loaded with peanut proteins in a murine model of fatal anaphylaxis

Article • Immunotherapy, November 2017, Future Medicine

Professor Carlos Gamazo, Dr Marta Ferrer, Professor Juan M. Irache
Corrigendum to ‘Evaluation of the cytotoxicity, genotoxicity and mucus permeation capacity of several surface modified poly(anhydride) nanoparticles designed for oral drug delivery’ [International Journal of Pharmaceutics 517 (2017) 67-79]

Article • International Journal of Pharmaceutics, November 2017, Elsevier

Professor Juan M. Irache
Skin vaccination using microneedles coated with a plasmid DNA cocktail encoding nucleosomal histones of Leishmania spp.

Article • International Journal of Pharmaceutics, November 2017, Elsevier

Professor Juan M. Irache
Genotoxic evaluation of poly(anhydride) nanoparticles in the gastrointestinal tract of mice

Article • International Journal of Pharmaceutics, September 2017, Elsevier

Professor Juan M. Irache
Supramolecular structure of glibenclamide and β-cyclodextrins complexes

Article • International Journal of Pharmaceutics, September 2017, Elsevier

Professor Juan M. Irache
Adjuvants for allergy immunotherapeutics

Article • Human Vaccines & Immunotherapeutics, August 2017, Taylor & Francis

Dr Marta Ferrer, Professor Carlos Gamazo, Gabriel Gastaminza, Professor Juan M. Irache
Effective protection of mice against Shigella flexneri with a new self-adjuvant multicomponent vaccine

Article • Journal of Medical Microbiology, July 2017, Society for General Microbiology

Professor Juan M. Irache
Toxicity and biodistribution of orally administered casein nanoparticles

Article • Food and Chemical Toxicology, June 2017, Elsevier

Professor Juan M. Irache
Zein nanoparticles as vehicles for oral delivery purposes

Article • Nanomedicine, June 2017, Future Medicine

Professor Juan M. Irache
In vitro evaluation of the genotoxicity of poly(anhydride) nanoparticles designed for oral drug delivery

Article • International Journal of Pharmaceutics, May 2017, Elsevier

Professor Juan M. Irache
Nanoaggregation of inclusion complexes of glibenclamide with cyclodextrins

Article • International Journal of Pharmaceutics, March 2017, Elsevier

Professor Juan M. Irache
Topical immunization using a nanoemulsion containing bacterial membrane antigens

Article • Journal of Drug Delivery Science and Technology, February 2017, Elsevier

Professor Juan M. Irache, Professor Carlos Gamazo
Improved effect of amikacin-loaded Poly (D, L-lactide-co-glycolide) (PLGA) nanoparticles against Planktonic and biofilm cells of Pseudomonas aeruginosa

Article • Journal of Medical Microbiology, January 2017, Society for General Microbiology

Professor Juan M. Irache, Professor Carlos Gamazo
Effect of the oral administration of nanoencapsulated quercetin on a mouse model of Alzheimer’s disease

Article • International Journal of Pharmaceutics, January 2017, Elsevier

Professor Juan M. Irache
Evaluation of the cytotoxicity, genotoxicity and mucus permeation capacity of several surface modified poly(anhydride) nanoparticles designed for oral drug delivery

Article • International Journal of Pharmaceutics, January 2017, Elsevier

Professor Juan M. Irache
Zein nanoparticles for oral delivery of quercetin: Pharmacokinetic studies and preventive anti-inflammatory effects in a mouse model of endotoxemia

Article • Nanomedicine Nanotechnology Biology and Medicine, January 2017, Elsevier

Professor Juan M. Irache, Professor Carlos Gamazo
New pharmaceutical approaches for the treatment of food allergies

Article • Expert Opinion on Drug Delivery, October 2016, Taylor & Francis

Professor Carlos Gamazo, Professor Juan M. Irache
Amikacin loaded PLGA nanoparticles against Pseudomonas aeruginosa

Article • European Journal of Pharmaceutical Sciences, October 2016, Elsevier

Professor Juan M. Irache, Professor Carlos Gamazo
Poly lactic-co-glycolic acid controlled delivery of disulfiram to target liver cancer stem-like cells

Article • Nanomedicine Nanotechnology Biology and Medicine, August 2016, Elsevier

Professor Juan M. Irache
Synthesis of Electroneutralized Amphiphilic Copolymers with Peptide Dendrons for Intramuscular Gene Delivery

Article • ACS Applied Materials & Interfaces, June 2016, American Chemical Society (ACS)

Professor Juan M. Irache
Oral delivery of camptothecin using cyclodextrin/poly(anhydride) nanoparticles

Article • International Journal of Pharmaceutics, June 2016, Elsevier

Professor Juan M. Irache
Zein nanoparticles for oral folic acid delivery

Article • Journal of Drug Delivery Science and Technology, December 2015, Elsevier

Professor Juan M. Irache
Study of Thermal Degradation of PLGA, PLGA Nanospheres and PLGA/Maghemite Superparamagnetic Nanospheres

Article • December 2015, FapUNIFESP (SciELO)

Professor Juan M. Irache
Interactions of poly (anhydride) nanoparticles with macrophages in light of their vaccine adjuvant properties

Article • International Journal of Pharmaceutics, December 2015, Elsevier

Professor Juan M. Irache, Professor Carlos Gamazo
In vivo study of the mucus-permeating properties of PEG-coated nanoparticles following oral administration

Article • European Journal of Pharmaceutics and Biopharmaceutics, November 2015, Elsevier

Professor Juan M. Irache
Assessment of β-lapachone loaded in lecithin-chitosan nanoparticles for the topical treatment of cutaneous leishmaniasis in L. major infected BALB/c mice

Article • Nanomedicine Nanotechnology Biology and Medicine, November 2015, Elsevier

Professor Juan M. Irache
Toxicity evaluation of nanocarriers for the oral delivery of macromolecular drugs

Article • European Journal of Pharmaceutics and Biopharmaceutics, November 2015, Elsevier

Professor Juan M. Irache
Mimicking microbial strategies for the design of mucus-permeating nanoparticles for oral immunization

Article • European Journal of Pharmaceutics and Biopharmaceutics, October 2015, Elsevier

Professor Juan M. Irache, Professor Carlos Gamazo
Controlled Release, Intestinal Transport, and Oral Bioavailablity of Paclitaxel Can be Considerably Increased Using Suitably Tailored Pegylated Poly(Anhydride) Nanoparticles

Article • Journal of Pharmaceutical Sciences, September 2015, Elsevier

Professor Juan M. Irache
Abstract 4067: Pluronic micelle-encapsulated Disulfiram targets cancer stem-like cells and reverses pan-resistance in acquired resistant breast cancer cell lines

Article • Cancer Research, August 2015, American Association for Cancer Research (AACR)

Professor Petar Dimitrov Petrov, Professor Juan M. Irache
Zein-Based Nanoparticles Improve the Oral Bioavailability of Resveratrol and Its Anti-inflammatory Effects in a Mouse Model of Endotoxic Shock

Article • Journal of Agricultural and Food Chemistry, June 2015, American Chemical Society (ACS)

Professor Juan M. Irache, Professor Carlos Gamazo
Casein nanoparticles as carriers for the oral delivery of folic acid

Article • Food Hydrocolloids, February 2015, Elsevier

Professor Juan M. Irache
Co-Encapsulated CpG Oligodeoxynucleotides and Ovalbumin in PLGA Microparticles; An in vitro and in vivo Study

Article • Journal of Pharmacy & Pharmaceutical Sciences, December 2014, JPPS Journal

Professor Juan M. Irache
Topical treatment of L. major infected BALB/c mice with a novel diselenide chitosan hydrogel formulation

Article • European Journal of Pharmaceutical Sciences, October 2014, Elsevier

Professor Juan M. Irache
Nanoparticles as Adjuvants for Vaccination

Article • September 2014, World Scientific Pub Co Pte Lt

Professor Juan M. Irache, Professor Carlos Gamazo
Development of a Bacterial Nanoparticle Vaccine

Article • September 2014, Springer Science + Business Media

Professor Juan M. Irache, Professor Carlos Gamazo
Liposome encapsulated Disulfiram inhibits NFκB pathway and targets breast cancer stem cells in vitro and in vivo

Article • Oncotarget, September 2014, Impact Journals, LLC

Professor Juan M. Irache
Nanoparticle based-immunotherapy against allergy

Article • Immunotherapy, July 2014, Future Medicine

Dr Marta Ferrer, Professor Juan M. Irache, Professor Carlos Gamazo
Pharmacokinetics and antitumor efficacy of paclitaxel–cyclodextrin complexes loaded in mucus-penetrating nanoparticles for oral administration

Article • Nanomedicine, July 2014, Future Medicine

Professor Juan M. Irache
Immunogenicity of Peanut Proteins Containing Poly(Anhydride) Nanoparticles

Article • Clinical and Vaccine Immunology, June 2014, ASM Journals

Professor Carlos Gamazo, Dr Marta Ferrer, Professor Juan M. Irache
Influence of Cyclodextrin Derivatives on In Vitro Release of Cyclosporine A from Poly(anhydride) Nanoparticles

Article • Journal of Nanopharmaceutics and Drug Delivery, June 2014, American Scientific Publishers

Professor Juan M. Irache
Nanoparticles as multifunctional devices for the topical treatment of cutaneous leishmaniasis

Article • Expert Opinion on Drug Delivery, March 2014, Informa Healthcare

Professor Juan M. Irache
Vaccine Delivery Systems for Veterinary Immunization

Article • January 2014, Springer Science + Business Media

Professor Carlos Gamazo, Professor Juan M. Irache
Thermosensitive hydrogels of poly(methyl vinyl ether-co-maleic anhydride) – Pluronic® F127 copolymers for controlled protein release

Article • International Journal of Pharmaceutics, January 2014, Elsevier

Professor Juan M. Irache
Superparamagnetic maghemite loaded poly (?- caprolactone) nanocapsules : characterization and synthesis optimization

Article • Matéria (Rio de Janeiro), January 2014, FapUNIFESP (SciELO)

Professor Juan M. Irache, Ammad Farooqi
PLGA nanoparticles loaded with KMP-11 stimulate innate immunity and induce the killing of Leishmania

Article • Nanomedicine Nanotechnology Biology and Medicine, October 2013, Elsevier

Diego Santos, Professor Juan M. Irache
Antigen Delivery Systems as Oral Adjuvants

Article • September 2013, Springer Science + Business Media

Professor Carlos Gamazo, Professor Juan M. Irache
Cytotoxicity and Cell Interaction Studies of Bioadhesive Poly(anhydride) Nanoparticles for Oral Antigen/Drug Delivery

Article • Journal of Biomedical Nanotechnology, September 2013, American Scientific Publishers

Professor Juan M. Irache
Nanoparticle-based vaccine for mucosal protection against Shigella flexneri in mice

Article • Vaccine, July 2013, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Optimization of maghemite-loaded PLGA nanospheres for biomedical applications

Article • European Journal of Pharmaceutical Sciences, June 2013, Elsevier

Professor Juan M. Irache
Towards a non-living vaccine against Shigella flexneri: From the inactivation procedure to protection studies

Article • Methods, May 2013, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Nanoparticules mucopénétrantes : véhicules pour l’administration orale du paclitaxel

Article • Annales Pharmaceutiques Françaises, March 2013, Elsevier

Professor Juan M. Irache
Radiomarcaje y estudios de biodistribución de nanopartículas poliméricas como adyuvantes para la vacunación oftálmica frente a la brucelosis

Article • Revista Española de Medicina Nuclear e Imagen Molecular, March 2013, Elsevier

Professor Juan M. Irache, Professor Carlos Gamazo
Poly(ethylene oxide)-block-poly(n-butyl acrylate)-block-poly(acrylic acid) triblock terpolymers with highly asymmetric hydrophilic blocks: synthesis and aqueous solution properties

Article • Soft Matter, January 2013, Royal Society of Chemistry

Professor Petar Dimitrov Petrov, Professor Juan M. Irache
Recent progress towards development of aShigellavaccine

Article • Expert Review of Vaccines, January 2013, Taylor & Francis

Professor Carlos Gamazo, Professor Juan M. Irache
Development of poly(anhydride) nanoparticles loaded with peanut proteins: The influence of preparation method on the immunogenic properties

Article • European Journal of Pharmaceutics and Biopharmaceutics, October 2012, Elsevier

Professor Carlos Gamazo, Dr Marta Ferrer, Professor Juan M. Irache
Stabilized micelles as delivery vehicles for paclitaxel

Article • International Journal of Pharmaceutics, October 2012, Elsevier

Professor Petar Dimitrov Petrov, Professor Juan M. Irache
Conjunctival vaccination against Brucella ovis in mice with mannosylated nanoparticles

Article • Journal of Controlled Release, September 2012, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Innovative Lead Compounds and Formulation Strategies As Newer Kinetoplastid Therapies

Article • Current Medicinal Chemistry, September 2012, Bentham Science Publishers

Professor Juan M. Irache, Professor Daniel Plano Amatriain
Oral administration of paclitaxel with pegylated poly(anhydride) nanoparticles: Permeability and pharmacokinetic study

Article • European Journal of Pharmaceutics and Biopharmaceutics, August 2012, Elsevier

Professor Juan M. Irache
Low efficacy of NcGRA7, NcSAG4, NcBSR4 and NcSRS9 formulated in poly-ɛ-caprolactone against Neospora caninum infection in mice

Article • Vaccine, July 2012, Elsevier

Professor Juan M. Irache
Toxicity Studies of Poly(Anhydride) Nanoparticles as Carriers for Oral Drug Delivery

Article • Pharmaceutical Research, May 2012, Springer Science + Business Media

Professor Juan M. Irache
Nuevas formas farmacéuticas para el tratamiento de enfermedades alérgicas

Article • Anales del Sistema Sanitario de Navarra, April 2012, Instituto de Salud Carlos III/BNCS/SciELO Espana

Professor Juan M. Irache
Chapter 2.3. Nanostructures for Oral Vaccine Delivery

Article • January 2012, Royal Society of Chemistry

Professor Carlos Gamazo, Professor Juan M. Irache
Acellular vaccines for ovine brucellosis: a safer alternative against a worldwide disease

Article • Expert Review of Vaccines, January 2012, Taylor & Francis

Professor Carlos Gamazo, Professor Juan M. Irache
Nanoparticulate Adjuvants and Delivery Systems for Allergen Immunotherapy

Article • Journal of Biomedicine and Biotechnology, January 2012, Hindawi Publishing Corporation

Professor Carlos Gamazo, Dr Marta Ferrer, Professor Juan M. Irache
Molecular buckets: cyclodextrins for oral cancer therapy

Article • Therapeutic Delivery, January 2012, Future Science

Professor Juan M. Irache
Gantrez AN Nanoparticles for Ocular Delivery of Memantine: In vitro Release Evaluation in Albino Rabbits

Article • Ophthalmic Research, January 2012, Karger Publishers

Professor Juan M. Irache
Mucosal immunization with Shigella flexneri outer membrane vesicles induced protection in mice

Article • Vaccine, October 2011, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Poly(methyl vinyl ether-co-maleic anhydride) nanoparticles as innate immune system activators

Article • Vaccine, September 2011, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Nanomedicine: Novel approaches in human and veterinary therapeutics

Article • Veterinary Parasitology, August 2011, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Cyclodextrin/poly(anhydride) nanoparticles as drug carriers for the oral delivery of atovaquone

Article • Biomedical Microdevices, July 2011, Springer Science + Business Media

Professor Juan M. Irache
Bioadhesive properties of poly(anhydride) nanoparticles coated with different molecular weights chitosan

Article • Journal of Microencapsulation, May 2011, Taylor & Francis

Professor Juan M. Irache
Cyclodextrin-poly(anhydride) nanoparticles as new vehicles for oral drug delivery

Article • Expert Opinion on Drug Delivery, April 2011, Informa Healthcare

Professor Juan M. Irache
Nanoparticles for the Oral Administration of Cancer Therapies

Article • January 2011, Springer Science + Business Media

Professor Juan M. Irache
Molecular Imaging Techniques to Study the Biodistribution of Orally Administered 99mTc-Labelled Naive and Ligand-Tagged Nanoparticles

Article • Molecular Imaging and Biology, December 2010, Springer Science + Business Media

Professor Juan M. Irache
Poly(Anhydride) Nanoparticles Act as Active Th1 Adjuvants through Toll-Like Receptor Exploitation

Article • Clinical and Vaccine Immunology, July 2010, ASM Journals

Professor Carlos Gamazo, Professor Juan M. Irache
Increased oral bioavailability of paclitaxel by its encapsulation through complex formation with cyclodextrins in poly(anhydride) nanoparticles

Article • Journal of Controlled Release, July 2010, Elsevier

Professor Juan M. Irache
Toxicity studies of poly(anhydride) nanoparticles

Article • Toxicology Letters, July 2010, Elsevier

Professor Juan M. Irache
Influence of dextran on the bioadhesive properties of poly(anhydride) nanoparticles

Article • International Journal of Pharmaceutics, May 2010, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Evaluation of particulate acellular vaccines against Brucella ovis infection in rams

Article • Vaccine, April 2010, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Influence of the chitosan nature on the transfection efficacy of DNA-loaded nanoparticles after hydrodynamic administration in mice

Article • Journal of Microencapsulation, February 2010, Taylor & Francis

Professor Juan M. Irache
Different approaches for determination of the attachment degree of polyethylene glycols to poly(anhydride) nanoparticles

Article • Drug Development and Industrial Pharmacy, January 2010, Taylor & Francis

Professor Juan M. Irache
Poly anhydride nanoparticles as adjuvants for mucosal vaccination

Article • January 2010, Frontiers in Bioscience

Professor Juan M. Irache
Combined hydroxypropyl-β-cyclodextrin and poly(anhydride) nanoparticles improve the oral permeability of paclitaxel

Article • European Journal of Pharmaceutical Sciences, November 2009, Elsevier

Professor Juan M. Irache
New adjuvants: from empiricism to science

Article • Expert Review of Vaccines, October 2009, Taylor & Francis

Professor Carlos Gamazo, Professor Juan M. Irache
A novel nanoparticulate adjuvant for immunotherapy with Lolium perenne

Article • Journal of Immunological Methods, August 2009, Elsevier

Professor Carlos Gamazo, Dr Marta Ferrer, Professor Juan M. Irache
Immunoadjuvant capacity of flagellin and mannosamine-coated poly(anhydride) nanoparticles in oral vaccination

Article • Vaccine, July 2009, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Design and influence of γ-irradiation on the biopharmaceutical properties of nanoparticles containing an antigenic complex from Brucella ovis

Article • European Journal of Pharmaceutical Sciences, July 2009, Elsevier

Professor Juan M. Irache, Professor Carlos Gamazo
Bioadhesive properties and biodistribution of cyclodextrin–poly(anhydride) nanoparticles

Article • European Journal of Pharmaceutical Sciences, June 2009, Elsevier

Professor Juan M. Irache
Protection from Staphylococcus aureus mastitis associated with poly-N-acetyl β-1,6 glucosamine specific antibody production using biofilm-embedded bacteria

Article • Vaccine, April 2009, Elsevier

Professor Juan M. Irache
Co-Delivery of Ovalbumin and CpG Motifs into Microparticles Protected Sensitized Mice from Anaphylaxis

Article • International Archives of Allergy and Immunology, January 2009, Karger Publishers

Professor Carlos Gamazo, Professor Juan M. Irache
Allergen immunotherapy with nanoparticles containing lipopolysaccharide from Brucella ovis

Article • European Journal of Pharmaceutics and Biopharmaceutics, November 2008, Elsevier

Professor Carlos Gamazo, Dr Marta Ferrer, Professor Juan M. Irache
Stability of Poly(ε-caprolactone) Microparticles Containing Brucella ovis Antigens as a Vaccine Delivery System Against Brucellosis

Article • AAPS PharmSciTech, October 2008, American Association of Pharmaceutical Scientists (AAPS)

Professor Carlos Gamazo, Professor Juan M. Irache
New methodologies to characterize the effectiveness of the gene transfer mediated by DNA-chitosan nanoparticles

Article • International Journal of Nanomedicine, October 2008, Dove Medical Press

Professor Juan M. Irache
Co-encapsulation of an antigen and CpG oligonucleotides into PLGA microparticles by TROMS technology

Article • European Journal of Pharmaceutics and Biopharmaceutics, September 2008, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Evaluation of Bioadhesive Capacity and Immunoadjuvant Properties of Vitamin B12-Gantrez Nanoparticles

Article • Pharmaceutical Research, August 2008, Springer Science + Business Media

Professor Carlos Gamazo, Professor Juan M. Irache
Mannose-targeted systems for the delivery of therapeutics

Article • Expert Opinion on Drug Delivery, June 2008, Informa Healthcare

Professor Carlos Gamazo, Professor Juan M. Irache
Nanomedicina: nanopartículas con aplicaciones médicas

Article • Anales del Sistema Sanitario de Navarra, April 2008, Instituto de Salud Carlos III/BNCS/SciELO Espana

Professor Juan M. Irache
Development of bioadhesive amino-pegylated poly(anhydride) nanoparticles designed for oral DNA delivery

Article • Journal of Microencapsulation, January 2008, Taylor & Francis

Professor Juan M. Irache
Bioadhesive capacity and immunoadjuvant properties of thiamine-coated nanoparticles

Article • Vaccine, November 2007, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Albumin Nanoparticles

Article • September 2007, Wiley

Professor Juan M. Irache
Plant Protein-based Nanoparticles

Article • September 2007, Wiley

Professor Juan M. Irache
An HPLC with evaporative light scattering detection method for the quantification of PEGs and Gantrez in PEGylated nanoparticles

Article • Journal of Pharmaceutical and Biomedical Analysis, September 2007, Elsevier

Professor Juan M. Irache
Lyophilization of adenoviral vectors for gene therapy

Article • European Journal of Pharmaceutical Sciences, September 2007, Elsevier

Professor Juan M. Irache
Gantrez® AN nanoparticles as an adjuvant for oral immunotherapy with allergens

Article • Vaccine, July 2007, Elsevier

Professor Carlos Gamazo, Dr Marta Ferrer, Professor Juan M. Irache
Protective immunity of biodegradable nanoparticle-based vaccine against an experimental challenge with Salmonella Enteritidis in mice

Article • Vaccine, May 2007, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Evaluation of bioadhesive potential and intestinal transport of pegylated poly(anhydride) nanoparticles

Article • International Journal of Pharmaceutics, April 2007, Elsevier

Professor Juan M. Irache
Nanoparticles as Adjuvant-Vectors for Vaccination

Article • March 2007, Taylor & Francis

Professor Carlos Gamazo, Professor Juan M. Irache
Intradermal immunization with ovalbumin-loaded poly-?-caprolactone microparticles conferred protection in ovalbumin-sensitized allergic mice

Article • Clinical & Experimental Allergy, February 2007, Wiley

Professor Carlos Gamazo, Dr Marta Ferrer, Professor Juan M. Irache
Gamma Interferon Loaded onto Albumin Nanoparticles: In Vitro and In Vivo Activities against Brucella abortus

Article • Antimicrobial Agents and Chemotherapy, January 2007, ASM Journals

Professor Carlos Gamazo, Professor Juan M. Irache
Encapsulation of antigenic extracts of Salmonella enterica serovar

Article • Veterinary Microbiology, November 2006, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Chemical and Biological Factors in the Control of Brucella and Brucellosis

Article • Current Drug Delivery, October 2006, Bentham Science Publishers

Professor Carlos Gamazo, Professor Juan M. Irache, Professor Maria J Blanco-Prieto
Bioadhesive Mannosylated Nanoparticles for Oral Drug Delivery

Article • Journal of Nanoscience and Nanotechnology, September 2006, American Scientific Publishers

Professor Carlos Gamazo, Professor Juan M. Irache
Development of a Novel Vaccine Delivery System Based on Gantrez Nanoparticles

Article • Journal of Nanoscience and Nanotechnology, September 2006, American Scientific Publishers

Professor Carlos Gamazo, Dr Marta Ferrer, Professor Juan M. Irache
Experiments on a sub-unit vaccine encapsulated in microparticles and its efficacy against Brucella melitensis in mice

Article • Vaccine, May 2006, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Brucella outer membrane complex-loaded microparticles as a vaccine against Brucella ovis in rams

Article • Vaccine, March 2006, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Optimization of the entrapment of bacterial cell envelope extracts into microparticles for vaccine delivery

Article • Journal of Microencapsulation, January 2006, Taylor & Francis

Professor Carlos Gamazo, Professor Juan M. Irache
Simultaneous quantification of different cyclodextrins and Gantrez by HPLC with evaporative light scattering detection

Article • Journal of Pharmaceutical and Biomedical Analysis, September 2005, Elsevier

Professor Juan M. Irache
Salmonella-like bioadhesive nanoparticles

Article • Journal of Controlled Release, August 2005, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Gentamicin-loaded microspheres for treatment of experimental Brucella abortus infection in mice

Article • Journal of Antimicrobial Chemotherapy, April 2005, Oxford University Press (OUP)

Professor Juan M. Irache, Professor Carlos Gamazo
Pegylated nanoparticles based on poly(methyl vinyl ether-co-maleic anhydride): preparation and evaluation of their bioadhesive properties

Article • European Journal of Pharmaceutical Sciences, April 2005, Elsevier

Professor Juan M. Irache
Bioadhesive properties of pegylated nanoparticles

Article • Expert Opinion on Drug Delivery, March 2005, Informa Healthcare

Professor Carlos Gamazo, Professor Juan M. Irache
Albumin Nanoparticles for the Intravitreal Delivery of Anticytomegaloviral Drugs

Article • Mini-Reviews in Medicinal Chemistry, March 2005, Bentham Science Publishers

Professor Juan M. Irache
Potential of Albumin Nanoparticles as Carriers for Interferon Gamma

Article • Drug Development and Industrial Pharmacy, March 2005, Taylor & Francis

Professor Juan M. Irache
Protective ability of subcellular extracts from Salmonella Enteritidis and from a rough isogenic mutant against salmonellosis in mice

Article • Vaccine, February 2005, Elsevier

Professor Juan M. Irache, Professor Carlos Gamazo
Bioadhesive Properties of Gantrez Nanoparticles

Article • Molecules, January 2005, MDPI AG

Professor Juan M. Irache
Potential of Albumin Nanoparticles as Carriers for Interferon Gamma

Article • Drug Development and Industrial Pharmacy, January 2005, Taylor & Francis

Professor Juan M. Irache
Humoral immune response in hens naturally infected withSalmonellaEnteritidis against outer membrane proteins and other surface structural antigens

Article • Veterinary Research, May 2004, EDP Sciences

Professor Carlos Gamazo, Professor Juan M. Irache
Gentamicin-loaded microspheres for reducing the intracellular Brucella abortus load in infected monocytes

Article • Journal of Antimicrobial Chemotherapy, April 2004, Oxford University Press (OUP)

Professor Juan M. Irache, Professor Carlos Gamazo
Nanoparticles with specific bioadhesive properties to circumvent the pre-systemic degradation of fluorinated pyrimidines

Article • Journal of Controlled Release, April 2004, Elsevier

Professor Juan M. Irache
New Therapeutic Approaches for the Treatment of Brucella Infections: Gentamicin Entrapment into Drug Delivery Systems

Article • Current Medicinal Chemistry - Anti-Infective Agents, March 2004, Bentham Science Publishers

Professor Carlos Gamazo, Professor Juan M. Irache
Influence of the co-encapsulation of different excipients on the properties of polyester microparticle-based vaccine against brucellosis

Article • International Journal of Pharmaceutics, March 2004, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
In vivo sustained release of adenoviral vectors from poly(d,l-lactic-co-glycolic) acid microparticles prepared by TROMS

Article • Journal of Controlled Release, January 2004, Elsevier

Professor Juan M. Irache
Albumin nanoparticles improved the stability, nuclear accumulation and anticytomegaloviral activity of a phosphodiester oligonucleotide

Article • Journal of Controlled Release, January 2004, Elsevier

Professor Juan M. Irache
Fluconazole encapsulation in PLGA microspheres by spray-drying

Article • Journal of Microencapsulation, January 2004, Taylor & Francis

Professor Juan M. Irache
Polymeric carriers for amphotericin B: in vitro activity, toxicity and therapeutic efficacy against systemic candidiasis in neutropenic mice

Article • Journal of Antimicrobial Chemotherapy, August 2003, Oxford University Press (OUP)

Professor Juan M. Irache, Professor Carlos Gamazo
Bovine Serum Albumin Modified the Intracellular Distribution and Improved the Antiviral Activity of an Oligonucleotide

Article • Journal of Drug Targeting, May 2003, Taylor & Francis

Professor Juan M. Irache
Influence of the surface characteristics of PVM/MA nanoparticles on their bioadhesive properties

Article • Journal of Controlled Release, April 2003, Elsevier

Professor Juan M. Irache
Corrigendum to: “Gantrez® AN as a new polymer for the preparation of ligand–nanoparticle conjugates”

Article • Journal of Controlled Release, March 2003, Elsevier

Professor Juan M. Irache
Loading of plasmid DNA into PLGA microparticles using TROMS (Total Recirculation One-Machine System): evaluation of its integrity and controlled release properties

Article • Journal of Controlled Release, January 2003, Elsevier

Professor Juan M. Irache
Modulation of the cellular immune response after oral or subcutaneous immunization with microparticles containing Brucella ovis antigens

Article • Journal of Controlled Release, December 2002, Elsevier

Professor Juan M. Irache, Professor Carlos Gamazo
Gantrez® AN as a new polymer for the preparation of ligand–nanoparticle conjugates

Article • Journal of Controlled Release, October 2002, Elsevier

Professor Juan M. Irache
Albumin nanoparticles as carriers for a phosphodiester oligonucleotide

Article • International Journal of Pharmaceutics, September 2002, Elsevier

Professor Juan M. Irache
Development of microparticles prepared by spray-drying as a vaccine delivery system against brucellosis

Article • International Journal of Pharmaceutics, August 2002, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache, Professor Maria J Blanco-Prieto
Quantification of the bioadhesive properties of protein-coated PVM/MA nanoparticles

Article • International Journal of Pharmaceutics, August 2002, Elsevier

Professor Juan M. Irache
RP–LC determination of 5-fluorouridine in nanoparticulate formulations

Article • Journal of Pharmaceutical and Biomedical Analysis, June 2002, Elsevier

Professor Juan M. Irache
Ocular disposition and tolerance of ganciclovir-loaded albumin nanoparticles after intravitreal injection in rats

Article • Biomaterials, April 2002, Elsevier

Professor Juan M. Irache
In vitro phagocytosis and monocyte-macrophage activation with poly(lactide) and poly(lactide-co-glycolide) microspheres

Article • European Journal of Pharmaceutical Sciences, March 2002, Elsevier

Professor Carlos Gamazo, Professor Hans P Merkle, Professor Juan M. Irache
Polyester Microparticles as a Vaccine Delivery System for Brucellosis: Influence of the Polymer on Release, Phagocytosis and Toxicity

Article • Journal of Drug Targeting, January 2002, Taylor & Francis

Professor Carlos Gamazo, Professor Juan M. Irache
Efficacy of Ganciclovir-loaded Nanoparticles in Human Cytomegalovirus (HCMV)-infected Cells

Article • Journal of Drug Targeting, January 2002, Taylor & Francis

Professor Juan M. Irache
Adaptive Immune Responses of Legumin Nanoparticles

Article • Journal of Drug Targeting, January 2002, Taylor & Francis

Professor Juan M. Irache
In Vitro Antileishmanial Activity of Amphotericin B Loaded in Poly(ε-Caprolactone) Nanospheres

Article • Journal of Drug Targeting, January 2002, Taylor & Francis

Professor Juan M. Irache
A Brucella ovis antigenic complex bearing poly-ε-caprolactone microparticles confer protection against experimental brucellosis in mice

Article • Vaccine, July 2001, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Ganciclovir-loaded albumin nanoparticles: characterization and in vitro release properties

Article • European Journal of Pharmaceutical Sciences, January 2001, Elsevier

Professor Juan M. Irache
Article • Pharmaceutical Research, January 2001, Springer Science + Business Media

Professor Juan M. Irache
Rapid determination of intramacrophagic amphotericin B by direct injection HPLC

Article • Chromatographia, December 2000, Springer Science + Business Media

Professor Juan M. Irache
Bioadhesive potential of gliadin nanoparticulate systems

Article • European Journal of Pharmaceutical Sciences, October 2000, Elsevier

Professor Juan M. Irache
In Vitro Reversion of Amphotericin B Resistance in Leishmania donovani by Poloxamer 188

Article • Antimicrobial Agents and Chemotherapy, August 2000, ASM Journals

Professor Juan M. Irache
RESEARCH NOTE - Evaluation and Characterisation of Gliadin Nanoparticles and Isolates by Reversed-Phase HPLC

Article • Journal of Cereal Science, March 2000, Elsevier

Professor Juan M. Irache
Gentamicin encapsulation in PLA/PLGA microspheres in view of treating Brucella infections

Article • International Journal of Pharmaceutics, February 2000, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Determination of oligonucleotide ISIS 2922 in nanoparticulate delivery systems by capillary zone electrophoresis

Article • Journal of Chromatography A, February 2000, Elsevier

Professor Juan M. Irache
Development of a sensitive method for the determination of ganciclovir by reversed-phase high-performance liquid chromatography

Article • Journal of Chromatography A, February 2000, Elsevier

Professor Juan M. Irache
Biopolymer and polymer nanoparticles and their biomedical applications

Article • January 2000, Elsevier

Professor Juan M. Irache
Distribution of Albumin Nanoparticles in Animals Induced with the Experimental Allergic Encephalomyelitis

Article • Journal of Drug Targeting, January 2000, Taylor & Francis

Professor Juan M. Irache
Preparation of Ulex europaeus lectin-gliadin nanoparticle conjugates and their interaction with gastrointestinal mucus

Article • International Journal of Pharmaceutics, November 1999, Elsevier

Professor Juan M. Irache
Electrophoretic separation and characterisation of gliadin fractions from isolates and nanoparticulate drug delivery systems

Article • Chromatographia, August 1999, Springer Science + Business Media

Professor Juan M. Irache
Gliadin nanoparticles: formation, all‐ trans‐retinoic acid entrapment and release, size optimization

Article • Polymer International, April 1999, Wiley

Professor Juan M. Irache
Gliadin nanoparticles: formation, all-trans-retinoic acid entrapment and release, size optimization

Article • Polymer International, April 1999, Wiley

Professor Juan M. Irache
Specific and non-specific bioadhesive particulate systems for oral delivery to the gastrointestinal tract

Article • Advanced Drug Delivery Reviews, December 1998, Elsevier

Professor Juan M. Irache
Interaction of amphotericin B with polymeric colloids

Article • Colloids and Surfaces B Biointerfaces, July 1998, Elsevier

Professor Juan M. Irache
Interaction of amphotericin B with polymeric colloids: 2. Effect of poloxamer on the adsorption of amphotericin B onto poly(ϵ-caprolactone) nanospheres

Article • Colloids and Surfaces B Biointerfaces, July 1998, Elsevier

Professor Juan M. Irache
Development of Drug-delivery Systems from Vegetal Proteins: All-trans-retinoic Acid-loaded Gliadin Nanoparticles

Article • January 1998, Springer Science + Business Media

Professor Juan M. Irache
Poly(ε-caprolacton) nanospheres as an alternative way to reduce amphotericin B toxicity

Article • International Journal of Pharmaceutics, December 1997, Elsevier

Professor Carlos Gamazo, Professor Juan M. Irache
Preparation of lectin-vicilin nanoparticle conjugates using the carbodiimide coupling technique

Article • International Journal of Pharmaceutics, October 1996, Elsevier

Professor Juan M. Irache
Gliadin nanoparticles for the controlled release of all-trans-retinoic acid

Article • International Journal of Pharmaceutics, April 1996, Elsevier

Professor Juan M. Irache
Development of Drug Delivery Systems from Vegetal Proteins: Legumin Nanoparticles

Article • Drug Development and Industrial Pharmacy, January 1996, Taylor & Francis

Professor Juan M. Irache
Article • Pharmaceutical Research, January 1996, Springer Science + Business Media

Professor Juan M. Irache
Optimization and in vitro stability of legumin nanoparticles obtained by a coacervation method

Article • International Journal of Pharmaceutics, December 1995, Elsevier

Professor Juan M. Irache
Mucin Interactions with Functionalized Polystyrene Latexes

Article • Journal of Colloid and Interface Science, March 1995, Elsevier

Professor Juan M. Irache
In vitro study of lectin-latex conjugates for specific bioadhesion

Article • Journal of Controlled Release, September 1994, Elsevier

Professor Juan M. Irache
Preparation and characterization of lectin-latex conjugates for specific bioadhesion

Article • Biomaterials, September 1994, Elsevier

Professor Juan M. Irache
Article • Pharmaceutical Research, January 1994, Springer Science + Business Media

Professor Juan M. Irache
Article • Pharmaceutical Research, January 1994, Springer Science + Business Media

Professor Juan M. Irache
Stability of some phenolic antioxidants in fatty preparations

Article • Pharmaceutica Acta Helvetiae, September 1993, Elsevier

Professor Juan M. Irache
Determination of particle concentration in latexes by turbidimetry

Article • International Journal of Pharmaceutics, March 1993, Elsevier

Professor Juan M. Irache
HPLC determination of antioxidant synergists and ascorbic acid in some fatty pharmaceuticals, cosmetics and food

Article • Chromatographia, February 1993, Springer Science + Business Media

Professor Juan M. Irache
NANOPARTICLES FOR ORAL VACCINATION

Article • World Scientific Pub Co Pte Lt

Professor Carlos Gamazo, Professor Juan M. Irache
Study of the interactions between nanoparticles and intestinal mucosa

Article • Springer Science + Business Media

Professor Juan M. Irache

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