All Stories

  1. Chronic Exposure to Chlorpyrifos Damages Thyroid Activity and Imbalances Hepatic Thyroid Hormones Signaling and Glucose Metabolism: Dependency of T3-FOXO1 Axis by Hyperglycemia

    Article • International Journal of Molecular Sciences, May 2023, MDPI AG

    Professor Massimo Mallardo

  2. The Lack of STING Impairs the MHC-I Dependent Antigen Presentation and JAK/STAT Signaling in Murine Macrophages

    Article • International Journal of Molecular Sciences, November 2022, MDPI AG

    Professor Massimo Mallardo

  3. Thyroid Cancer and Fibroblasts

    Article • Cancers, August 2022, MDPI AG

    Professor Massimo Mallardo

  4. miRNA-23a modulates sodium-hydrogen exchanger 1 expression: studies in medullary thick ascending limb of salt-induced hypertensive rats

    Article • Nephrology Dialysis Transplantation, August 2022, Oxford University Press (OUP)

    Professor Massimo Mallardo

  5. ZFP36L2 Role in Thyroid Functionality

    Article • International Journal of Molecular Sciences, August 2021, MDPI AG

    Professor Massimo Mallardo

  6. Application of Bioactive Compounds and Drugs to Target Epigenetic Enzymes and Non-coding RNAs, Exploiting New Delivery Systems for Cancer Therapy

    Article • Anti-Cancer Agents in Medicinal Chemistry, January 2021, Bentham Science Publishers

    Ammad Farooqi, Professor Massimo Mallardo, palmiro poltronieri

  7. Generation of a Novel Mesothelin-Targeted Oncolytic Herpes Virus and Implemented Strategies for Manufacturing

    Article • International Journal of Molecular Sciences, January 2021, MDPI AG

    Professor Massimo Mallardo

  8. Integrity of the Antiviral STING-mediated DNA Sensing in Tumor Cells Is Required to Sustain the Immunotherapeutic Efficacy of Herpes Simplex Oncolytic Virus

    Article • Cancers, November 2020, MDPI AG

    Professor Massimo Mallardo

  9. Peripheral T3 signaling is the target of pesticides in zebrafish larvae and adult liver

    Article • Journal of Endocrinology, October 2020, Bioscientifica

    Professor Massimo Mallardo

  10. Epigenetic deregulation in cancer: Enzyme players and non-coding RNAs

    Article • Seminars in Cancer Biology, July 2020, Elsevier

    Ammad Farooqi, Professor Massimo Mallardo

  11. Thyroid Hormones and Functional Ovarian Reserve: Systemic vs. Peripheral Dysfunctions

    Article • Journal of Clinical Medicine, June 2020, MDPI AG

    Professor Massimo Mallardo

  12. Editorial

    Article • Seminars in Cancer Biology, October 2019, Elsevier

    Ammad Farooqi, Professor Massimo Mallardo

  13. Insights into Thymus Development and Viral Thymic Infections

    Article • Viruses, September 2019, MDPI AG

    Professor Massimo Mallardo

  14. Effects of Long-Term Citrate Treatment in the PC3 Prostate Cancer Cell Line

    Article • International Journal of Molecular Sciences, May 2019, MDPI AG

    Professor Massimo Mallardo

  15. Activation of NF-κB in B cell receptor signaling through Bruton’s tyrosine kinase-dependent phosphorylation of IκB-α

    Article • Journal of Molecular Medicine, March 2019, Springer Science + Business Media

    Professor Massimo Mallardo

  16. A Toxicogenomic Approach Reveals a Novel Gene Regulatory Network Active in In Vitro and In Vivo Models of Thyroid Carcinogenesis

    Article • International Journal of Environmental Research and Public Health, January 2019, MDPI AG

    Professor Massimo Mallardo

  17. Transcriptional landscape of mouse-aged ovaries reveals a unique set of non-coding RNAs associated with physiological and environmental ovarian dysfunctions

    Article • Cell Death Discovery, December 2018, Springer Science + Business Media

    Professor Massimo Mallardo

  18. Genetic background and window of exposure contribute to thyroid dysfunction promoted by low-dose exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice

    Article • Scientific Reports, November 2018, Springer Science + Business Media

    Professor Massimo Mallardo

  19. The expression of inhibitor of bruton’s tyrosine kinase gene is progressively up regulated in the clinical course of chronic lymphocytic leukaemia conferring resistance to apoptosis

    Article • Cell Death and Disease, January 2018, Springer Science + Business Media

    Professor Massimo Mallardo

  20. Carcinogenic risk and Bisphenol A exposure: A focus on molecular aspects in endoderm derived glands

    Article • Molecular and Cellular Endocrinology, December 2017, Elsevier

    Professor Massimo Mallardo

  21. Pesticide toxicogenomics across scales: in vitro transcriptome predicts mechanisms and outcomes of exposure in vivo

    Article • Scientific Reports, December 2016, Springer Science + Business Media

    Professor Massimo Mallardo

  22. Roles of microRNAs in HIV-1 Replication and Latency

    Article • MicroRNA, November 2016, Bentham Science Publishers

    Professor Massimo Mallardo

  23. The Roles of miR-25 and its Targeted Genes in Development of Human Cancer

    Article • MicroRNA, November 2016, Bentham Science Publishers

    Professor Massimo Mallardo

  24. Molecular targets of developmental exposure to bisphenol A in diabesity: a focus on endoderm-derived organs

    Article • Obesity Reviews, October 2016, Wiley

    Professor Massimo Mallardo

  25. “Stockpile” of Slight Transcriptomic Changes Determines the Indirect Genotoxicity of Low-Dose BPA in Thyroid Cells

    Article • PLoS ONE, March 2016, PLOS

    Professor Massimo Mallardo

  26. Evaluation of low doses BPA-induced perturbation of glycemia by toxicogenomics points to a primary role of pancreatic islets and to the mechanism of toxicity

    Article • Cell Death and Disease, October 2015, Springer Science + Business Media

    Professor Massimo Mallardo

  27. Impairment of T cell development and acute inflammatory response in HIV-1 Tat transgenic mice

    Article • Scientific Reports, September 2015, Nature

    Professor Massimo Mallardo

  28. RNA Viruses: RNA Roles in Pathogenesis, Coreplication and Viral Load

    Article • Current Genomics, July 2015, Bentham Science Publishers

    Professor Massimo Mallardo

  29. Pharmacological folding chaperones act as allosteric ligands of Frizzled4

    Article • Nature Methods, March 2015, Nature

    Professor Massimo Mallardo

  30. Cross-species toxicogenomic analyses and phenotypic anchoring in response to groundwater low-level pollution

    Article • BMC Genomics, January 2014, Springer Science + Business Media

    Professor Massimo Mallardo

  31. Cancer-Associated CD43 Glycoforms as Target of Immunotherapy

    Article • Molecular Cancer Therapeutics, December 2013, American Association for Cancer Research (AACR)

    Dr Maria Lina Tornesello , Professor Massimo Mallardo

  32. A disorder-to-order structural transition in the COOH-tail of Fz4 determines misfolding of the L501fsX533-Fz4 mutant

    Article • Scientific Reports, September 2013, Nature

    Professor Massimo Mallardo

  33. Bisphenol A interferes with thyroid specific gene expression

    Article • Toxicology, February 2013, Elsevier

    Professor Massimo Mallardo

  34. miR-155 is up-regulated in primary and secondary glioblastoma and promotes tumour growth by inhibiting GABA receptors

    Article • International Journal of Oncology, March 2012, Spandidos Publications

    Professor Massimo Mallardo

  35. FKBP51 and the NF-κB regulatory pathway in cancer

    Article • Current Opinion in Pharmacology, August 2011, Elsevier

    Professor Massimo Mallardo

  36. Non-coding RNAs change their expression profile after Retinoid induced differentiation of the promyelocytic cell line NB4

    Article • BMC Research Notes, January 2010, Springer Science + Business Media

    Professor Massimo Mallardo, Paolo Remondelli

  37. Endoplasmic reticulum stress reduces the export from the ER and alters the architecture of post-ER compartments

    Article • The International Journal of Biochemistry & Cell Biology, December 2009, Elsevier

    Professor Massimo Mallardo, Paolo Remondelli

  38. Computational analysis and in vivo validation of a microRNA encoded by the IBTK gene, a regulator of B-lymphocytes differentiation and survival

    Article • Computational Biology and Chemistry, December 2009, Elsevier

    Professor Massimo Mallardo

  39. Molecular mechanisms of dendritic mRNA localization and its implication for learning and memory

    Article • March 2009, Elsevier

    Professor Massimo Mallardo

  40. Epstein-Barr virus latent membrane protein 1 trans-activates miR-155 transcription through the NF- B pathway

    Article • Nucleic Acids Research, October 2008, Oxford University Press (OUP)

    Professor Massimo Mallardo

  41. Non-protein coding RNA biomarkers and differential expression in cancers: a review

    Article • Journal of Experimental & Clinical Cancer Research, January 2008, Springer Science + Business Media

    Professor Massimo Mallardo

  42. TEF-1 and C/EBPβ are major p38α MAPK-regulated transcription factors in proliferating cardiomyocytes

    Article • Biochemical Journal, May 2006, Portland Press Ltd.

    Professor Massimo Mallardo

  43. A GFP-based System to Uncouple mRNA Transport from Translation in a Single Living Neuron

    Article • Molecular Biology of the Cell, April 2003, American Society for Cell Biology (ASCB)

    Professor Massimo Mallardo

  44. Isolation and characterization of Staufen-containing ribonucleoprotein particles from rat brain

    Article • Proceedings of the National Academy of Sciences, February 2003, Proceedings of the National Academy of Sciences

    Professor Massimo Mallardo

  45. Relationship between Vaccinia Virus Intracellular Cores, Early mRNAs, and DNA Replication Sites

    Article • Journal of Virology, May 2002, ASM Journals

    Professor Massimo Mallardo

  46. Microtubule-dependent Organization of Vaccinia Virus Core-derivd Early mRNAs into Distinct Cytoplasmic Structures

    Article • Molecular Biology of the Cell, December 2001, American Society for Cell Biology (ASCB)

    Professor Massimo Mallardo

  47. Potent and Stable Attenuation of Live-HIV-1 by Gain of a Proteolysis-resistant Inhibitor of NF-κB (IκB-αS32/36A) and the Implications for Vaccine Development

    Article • Journal of Biological Chemistry, June 1999, Elsevier

    Professor Massimo Mallardo

  48. HIV-1 Tat Induces the Expression of the Interleukin-6 (IL6) Gene by Binding to the IL6 Leader RNA and by Interacting with CAAT Enhancer-binding Protein β (NF-IL6) Transcription Factors

    Article • Journal of Biological Chemistry, June 1997, Elsevier

    Professor Massimo Mallardo

  49. Regulation of HIV-1 Long Terminal Repeats by Interaction of C/EBP(NF-IL6) and NF-κB/Rel Transcription Factors

    Article • Journal of Biological Chemistry, September 1996, Elsevier

    Professor Massimo Mallardo

  50. An NF-κB Site in the 5′-Untranslated Leader Region of the Human Immunodeficiency Virus Type 1 Enhances the Viral Expression in Response to NF-κB-activating Stimuli

    Article • Journal of Biological Chemistry, August 1996, Elsevier

    Professor Massimo Mallardo

  51. Regulation of NF-kappaB through the Nuclear Processing of p105 (NF-kappaB1) in Epstein-Barr Virus-immortalized B Cell Lines

    Article • Journal of Biological Chemistry, December 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Massimo Mallardo

  52. The expression of the interleukin 6 gene is induced by the human immunodeficiency virus 1 TAT protein.

    Article • The Journal of Experimental Medicine, March 1994, Rockefeller University Press

    Professor Massimo Mallardo

  53. Molecular Mechanisms of the Development of EBV-Related B Lymphomas: Functional Cooperation of EBV with IL-6 and HIV-1

    Article • January 1994, Springer Science + Business Media

    Professor Massimo Mallardo

  54. Epstein-Barr virus nuclear antigen 2 transactivates the long terminal repeat of human immunodeficiency virus type 1

    Article • Journal of Virology, May 1993, ASM Journals

    Professor Massimo Mallardo

  55. Spontaneous and mutagen-mediated amplification of a neo gene integrated at different genomic sites in Rat 2 fibroblasts

    Article • Carcinogenesis, January 1992, Oxford University Press (OUP)

    Professor Massimo Mallardo

  56. Enhanced transcription of interleukin 1 (IL-1) and interleukin 6 (IL-6) in mutagen-treated human monocytes

    Article • Cytokine, September 1991, Elsevier

    Professor Massimo Mallardo

  57. Ultraviolet Mutagenesis

    Article • January 1991, Springer Science + Business Media

    Professor Massimo Mallardo

  58. Expression of an exogenous interleukin 6 gene in human Epstein Barr virus B cells confers growth advantage and in vivo tumorigenicity.

    Article • The Journal of Experimental Medicine, July 1990, Rockefeller University Press

    Professor Massimo Mallardo

  59. Effect of DNOC, Ferbam and Imidan exposure on mouse sperm morphology

    Article • Mutation Research/Genetic Toxicology, December 1989, Elsevier

    Professor Massimo Mallardo