All Stories

  1. Small molecule inhibition of voltage dependent anion channel 1 reroutes mitochondrial metabolite flux
  2. Multi-omics uncovers interaction in the vaginal microbiome and a type II secretion/Tad pilus system in Gardnerella vaginalis
  3. Klebsiella pneumoniae LPS drives stromal-mediated repression of p53 and colorectal cancer chemoresistance
  4. MitoSAM-dependent lipoylation controls postnatal heart development via metabolic remodeling
  5. Metabolic Reprogramming and Tunneling Nanotubes Cooperate to Regulate HIV-1 Latency Reactivation
  6. Acute high-dose irradiation disrupts cell adhesion and Silk-Ovarioid formation in human primary ovarian cells
  7. Profiling of Extracellular Vesicles of Non‐Small Cell Lung Cancer Reveals Proteins Associated With Osimertinib Resistance
  8. Pharmacological activation of p53 induces dose-dependent changes in endothelial cell fate during angiogenic sprouting
  9. Autoimmunity-associated DIORA1 binds the MRCK family of serine/threonine kinases and controls cell motility
  10. Toward a Species Search Engine: KISSE Offers a Rigorous Statistical Framework for Bone Collagen Tandem Mass Spectrometry Data
  11. Changes in circulating extracellular vesicle cargo are associated with cognitive decline after major surgery: an observational case–control study
  12. The Temporal Dynamics of Proteins in Aged Skin Wound Healing and Comparison with Gene Expression
  13. Comprehensive analysis of multi‐omics single‐cell data using the single‐cell analyst
  14. Collaborative Duality of CircGLIS3(2) RNA and Protein in human Wound Repair
  15. Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
  16. Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
  17. The proteome of osteoblasts in a 3D culture perfusion bioreactor model compared with static conditions
  18. Towards a species search engine: KISSE offers a rigorous statistical framework for bone collagen tandem mass spectrometry data
  19. Erythrocyte-derived extracellular vesicles induce endothelial dysfunction through arginase-1 and oxidative stress in type 2 diabetes
  20. Acute high-dose irradiation of human primary ovarian cells reveals a shift in transcriptomics profile and impairment in cell-cell adhesion
  21. Proteomic analysis reveals biomarkers associated with performance-based joint function and patient-reported outcomes in knee osteoarthritis
  22. Host Plasma Microenvironment in Immunometabolically Impaired HIV Infection Leads to Dysregulated Monocyte Function and Synaptic Transmission Ex Vivo
  23. Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
  24. The di-leucine motif in the host defense peptide LL-37 is essential for initiation of autophagy in human macrophages
  25. Silk-Ovarioids: establishment and characterization of a human ovarian primary cell 3D-model system
  26. SARS-CoV-2 variants mediated tissue-specific metabolic reprogramming determines the disease pathophysiology in a hamster model
  27. Characterization of the HLA-DR immunopeptidome of bronchoalveolar lavage cells in patients with newly diagnosed rheumatoid arthritis and healthy current-smoker controls
  28. Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
  29. microRNA and non-targeted proteome analysis of liquid biopsies from the distal lung collected by Particles in Exhaled Air (PExA) reveals presence from extracellular vesicles
  30. Bacterial extracellular vesicles as intranasal postbiotics: Detailed characterization and interaction with airway cells
  31. Mouse PAW: reverse-translating the FINGER multimodal lifestyle intervention enhances synaptic plasticity and cognition in adult wild type female mice
  32. Gel-Assisted Proteome Position Integral Shift Assay Returns Molecular Weight to Shotgun Proteomics and Identifies Caspase 3 Substrates
  33. Silk-Ovarioids: Establishment and characterization of human ovarian primary cells 3D-model system
  34. Network analysis reveals age‐ and virus‐specific circuits in nasal epithelial cells of extremely premature infants
  35. A multi-platform analysis of human gingival crevicular fluid reveals ferroptosis as a relevant regulated cell death mechanism during the clinical progression of periodontitis
  36. Abstract 5138: Proteomic analyses of the urothelial cancer landscape reveal highly distinct prognostic and predictive subtypes
  37. TISSUE-SPECIFIC METABOLOMIC REPROGRAMMING DETERMINES THE DISEASE PATHOPHYSIOLOGY OF SARS-COV-2 VARIANTS IN HAMSTER MODEL
  38. Gel-Assisted Proteome Position Integral Shift (GAPPIS) Assay Returns Molecular Weight to Shotgun Proteomics and Identifies Novel Caspase 3 Substrates
  39. 3D microperfusion of mesoscale human microphysiological liver models improves functionality and recapitulates hepatic zonation
  40. Toward Single Bacterium Proteomics
  41. Multifaceted proteome analysis at solubility, redox, and expression dimensions for target identification
  42. Analysis of local extracellular matrix identifies different aetiologies behind bicuspid and tricuspid aortic valve degeneration and suggests therapies
  43. Proteomic profile of human gingival crevicular fluid reveals specific biological and molecular processes during clinical progression of periodontitis
  44. Non-typeable Haemophilus influenzae major outer membrane protein P5 contributes to bacterial membrane stability, and affects the membrane protein composition crucial for interactions with the human host
  45. Distribution, cellular localization, and colocalization of several peptide neurotransmitters in the central nervous system ofAplysia
  46. Naturally occurring dipeptide from elite controllers with dual anti-HIV-1 mechanism
  47. NCF1-dependent production of ROS protects against lupus by regulating plasmacytoid dendritic cell development and functions
  48. Genomic adaptation underlies nutrient-driven reprogramming in the malaria-causing parasite
  49. Brain endothelial cells exposure to malaria parasites links type I interferon signalling to antigen presentation, immunoproteasome activation, endothelium disruption, and cellular metabolism
  50. Panomics reveals patient individuality as the major driver of colorectal cancer progression
  51. Impaired Immuno-Metabolic Homeostasis and Microenvironmental Influence on Neuropsychiatric Risk in Treated HIV Infection
  52. Brain endothelial cells exposure to malaria parasites links Type I interferon signalling to antigen presentation, immunoproteasome activation, endothelium disruption and cell metabolic adaptation
  53. Plasma proteomic profiling in postural orthostatic tachycardia syndrome (POTS) reveals new disease pathways
  54. Panomics reveals patient-individuality as the major driver for colorectal cancer progression
  55. Mapping the GALNT1 substrate landscape with versatile proteomics tools
  56. Single-Cell Chemical Proteomics (SCCP) Interrogates the Timing and Heterogeneity of Cancer Cell Commitment to Death
  57. Mass Spectrometry, Structural Analysis, and Anti-Inflammatory Properties of Photo-Cross-Linked Human Albumin Hydrogels
  58. Hepatocyte Thorns, A Novel Drug-Induced Stress Response in Human and Mouse Liver Spheroids
  59. Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target
  60. Peripheral blood CD4+CCR6+ compartment differentiates HIV-1 infected or seropositive elite controllers from long-term successfully treated individuals
  61. Epigenetic modulators link mitochondrial redox homeostasis to cardiac function
  62. Author response: Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target
  63. Nucleoside-Modified mRNA Vaccines Protect IFNAR –/– Mice against Crimean-Congo Hemorrhagic Fever Virus Infection
  64. Trans cohort metabolic reprogramming towards glutaminolysis in long-term successfully treated HIV-infection
  65. Integrative proteo-transcriptomic and immunophenotyping signatures of HIV-1 elite control phenotype: A cross-talk between glycolysis and HIF signaling
  66. Mass Spectrometry-Based Analytical Strategy for Single-Cell Proteomics
  67. Ultralight ultrafast enzymes
  68. Peripheral blood CD4+CCR6+ compartment differentiates HIV-1 infected or seropositive elite controllers from long-term successfully treated individuals
  69. Single Cell Proteomics Using Multiplexed Isobaric Labeling for Mass Spectrometric Analysis
  70. Citrullination Alters the Antibacterial and Anti-Inflammatory Functions of the Host Defense Peptide Canine Cathelicidin K9CATH In Vitro
  71. Trans Cohorts Metabolomic Modulation Following Long-Term Successful Therapy in HIV-Infection
  72. Coordinated pyruvate kinase activity is crucial for metabolic adaptation and cell survival during mitochondrial dysfunction
  73. Type-I interferon signatures in SARS-CoV-2 infected Huh7 cells
  74. Longitudinal blood cell transcriptomic profiling and in vitro temporal proteomics provides novel insights into metabolic reprogramming and host-immune responses against Crimean-Congo Hemorrhagic Fever Virus
  75. Cell-type-resolved quantitative proteomics map of interferon response against SARS-CoV-2
  76. Single Cell Chemical Proteomics (SCCP) Interrogates the Timing and Heterogeneity of Cancer Cell Commitment to Death
  77. Cytotoxic Lymphocytes Target HIV-1 Gag Through Granzyme M-Mediated Cleavage
  78. EPHA2 Interacts with DNA-PKcs in Cell Nucleus and Controls Ionizing Radiation Responses in Non-Small Cell Lung Cancer Cells
  79. System-wide identification and prioritization of enzyme substrates by thermal analysis
  80. The one-carbon pool controls mitochondrial energy metabolism via complex I and iron-sulfur clusters
  81. Metabolic Perturbation Associated With COVID-19 Disease Severity and SARS-CoV-2 Replication
  82. Single Cell Chemical Proteomics (SCCP) Interrogates the Timing and Heterogeneity of Cancer Cell Commitment to Death
  83. Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo Hemorrhagic Fever Viruses for novel therapeutic target
  84. Utility of Proteomics in Emerging and Re-Emerging Infectious Diseases Caused by RNA Viruses
  85. Mutant Proteomics of Lung Adenocarcinomas Harboring Different EGFR Mutations
  86. Correction: S100A6 is a critical regulator of hematopoietic stem cells
  87. S100A6 is a critical regulator of hematopoietic stem cells
  88. Dysregulation in mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells
  89. Studies on citrullinated LL-37: detection in human airways, antibacterial effects and biophysical properties
  90. Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells
  91. ProTargetMiner as a proteome signature library of anticancer molecules for functional discovery
  92. Current status of clinical proteogenomics in lung cancer
  93. Malondialdehyde Conjugated With Albumin Induces Pro-Inflammatory Activation of T Cells Isolated From Human Atherosclerotic Plaques Both Directly and Via Dendritic Cell–Mediated Mechanism
  94. System-wide identification and prioritization of enzyme substrates by thermal analysis (SIESTA)
  95. ProTargetMiner: A proteome signature library of anticancer molecules for functional discovery
  96. Deuteration of human carbonic anhydrase for neutron crystallography: Cell culture media, protein thermostability, and crystallization behavior
  97. Large Scale Identification of Variant Proteins in Glioma Stem Cells
  98. In vivo Distribution of Tiotropium in a Rodent Model Utilizing AP-SMALDI Mass Spectrometry Imaging
  99. Limited Tumor Tissue Drug Penetration Contributes to Primary Resistance against Angiogenesis Inhibitors
  100. Relationship between HMF intake and SMF formation in vivo: An animal and human study
  101. Localization of tamoxifen in human breast cancer tumors by MALDI mass spectrometry imaging
  102. Novel insights in drug metabolism by MS imaging
  103. Mutant Proteogenomics
  104. Proteogenomics
  105. Drug localizations in tissue by mass spectrometry imaging
  106. In Vitro Transcription/Translation System: A Versatile Tool in the Search for Missing Proteins
  107. Drug compound characterization by mass spectrometry imaging in cancer tissue
  108. Quest for Missing Proteins: Update 2015 on Chromosome-Centric Human Proteome Project
  109. Erratum to: Association of chromosome 19 to lung cancer genotypes and phenotypes
  110. Association of chromosome 19 to lung cancer genotypes and phenotypes
  111. Localization of sunitinib, its metabolites and its target receptors in tumour-bearing mice: a MALDI-MS imaging study
  112. Localization of sunitinib in in vivo animal and in vitro experimental models by MALDI mass spectrometry imaging
  113. Use of ENCODE Resources to Characterize Novel Proteoforms and Missing Proteins in the Human Proteome
  114. Systematic Identification of Single Amino Acid Variants in Glioma Stem-Cell-Derived Chromosome 19 Proteins
  115. SC-23 * THE ROLE OF SINGLE AMINO ACID POLYMORPHISMS IN GLIOMA STEM CELL PHENOTYPES
  116. A new look at drugs targeting malignant melanoma-An application for mass spectrometry imaging
  117. Aptamer/ISET-MS: A New Affinity-Based MALDI Technique for Improved Detection of Biomarkers
  118. Inflammatory markers in Huntington's disease plasma—A robust nanoLC–MRM-MS assay development
  119. Queries of MALDI-imaging global datasets identifying ion mass signatures associated with tissue compartments
  120. Identification of Missing Proteins: Toward the Completion of Human Proteome
  121. Integrated Chromosome 19 Transcriptomic and Proteomic Data Sets Derived from Glioma Cancer Stem-Cell Lines
  122. Developments in biobanking workflow standardization providing sample integrity and stability
  123. Experimental Models to Study Drug Distributions in Tissue Using MALDI Mass Spectrometry Imaging
  124. Accessing microenvironment compartments in formalin-fixed paraffin-embedded tissues by protein expression analysis
  125. Quantification of Human Kallikrein-2 in Clinical Samples by Selected Reaction Monitoring
  126. Identification of a Novel Proteoform of Prostate Specific Antigen (SNP-L132I) in Clinical Samples by Multiple Reaction Monitoring
  127. Development of an MRM assay panel with application to biobank samples from patients with myocardial infarction
  128. Blood Plasma Reference Material: A Global Resource for Proteomic Research
  129. Correlation Queries for Mass Spectrometry Imaging
  130. Establishing a Southern Swedish Malignant Melanoma OMICS and biobank clinical capability
  131. International biobanking for lung cancer and COPD as the future resource for clinical protein research
  132. Standardization developments for large scale biobanks in smoking related diseases - a model system for blood sample processing and storage
  133. A Critical Evaluation of Inflammatory Markers in Huntington's Disease Plasma
  134. Clinical and Biomedical Mass Spectrometry: New Frontiers in Drug Developments and Diagnosis
  135. Chromosome 19 Annotations with Disease Speciation: A First Report from the Global Research Consortium
  136. Large scale biobanking of blood — The importance of high density sample processing procedures
  137. Standardization and Utilization of Biobank Resources in Clinical Protein Science with Examples of Emerging Applications
  138. Molecular microheterogeneity of prostate specific antigen in seminal fluid by mass spectrometry
  139. Cancer Phenotype Diagnosis and Drug Efficacy within Japanese Health Care
  140. Clinical Proteomics
  141. Understanding drug uptake and binding within targeted disease micro-environments in patients: a new tool for translational medicine
  142. Bioinformatic strategies for unambiguous identification of prostate specific antigen in clinical samples
  143. MRM assay for quantitation of complement components in human blood plasma — a feasibility study on multiple sclerosis
  144. State-of-the-art MS technology applications in lung disease
  145. Direct Demonstration of Tissue Uptake of an Inhaled Drug: Proof-of-Principle Study Using Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging
  146. Drug localization in different lung cancer phenotypes by MALDI mass spectrometry imaging
  147. Biobank resources for future patient care: developments, principles and concepts
  148. Moving towards high density clinical signature studies with a human proteome catalogue developing multiplexing mass spectrometry assay panels
  149. Clinical Protein Science and Bioanalytical Mass Spectrometry with an Emphasis on Lung Cancer
  150. Essential tactics of tissue preparation and matrix nano-spotting for successful compound imaging mass spectrometry
  151. Identification of prostate-specific antigen (PSA) isoforms in complex biological samples utilizing complementary platforms
  152. Isotope labeled internal standards (ILIS) as a basis for quality control in clinical studies using plasma samples
  153. Multiple sclerosis: Identification and clinical evaluation of novel CSF biomarkers
  154. Determination of dissociation constants between polyelectrolytes and proteins by affinity capillary electrophoresis
  155. Identification of novel candidate protein biomarkers for the post-polio syndrome — Implications for diagnosis, neurodegeneration and neuroinflammation
  156. General Approach for Certain Quantitative Calculations for Instance of the Variance of Reversible Adsorption to the Capillary Wall in CE
  157. Isolation and characterization of a small antiretroviral molecule affecting HIV-1 capsid morphology
  158. Activity of the Small Modified Amino Acid α-Hydroxy Glycineamide on In Vitro and In Vivo Human Immunodeficiency Virus Type 1 Capsid Assembly and Infectivity
  159. Implementation of a protein profiling platform developed as an academic‐pharmaceutical industry collaborative effort
  160. Universal method for synthesis of artificial gel antibodies by the imprinting approach combined with a unique electrophoresis technique for detection of minute structural differences of proteins, viruses and cells (bacteria). Ib. Gel antibodies against...
  161. Universal method for synthesis of artificial gel antibodies by the imprinting approach combined with a unique electrophoresis technique for detection of minute structural differences of proteins, viruses, and cells (bacteria). III: Gel antibodies again...
  162. Theoretical and nomenclatural considerations of capillary electrochromatography with monolithic stationary phases
  163. Vitamin D receptor gene polymorphism in rheumatoid arthritis and associated osteoporosis
  164. Homogeneous gels for capillary electrochromatography
  165. T-cell recognition of differentially tolerated epitopes of cartilage proteoglycan aggrecan in arthritis
  166. Chapter 10 Technologies interfacing capillary electrophoresis to mass spectrometry
  167. Chapter 3 Peptide and protein separations by capillary electrophoresis and electrochromatography
  168. 2 Evolution and development of isoelectric focusing
  169. Hybrid microdevice electrophoresis of peptides, proteins, DNA, viruses, and bacteria in various separation media, using UV-detection
  170. High-Resolution Capillary Zone and Gel Electrophoresis of Structurally Similar Amphipathic Glutathione Conjugates Based on Interaction with -Cyclodextrins
  171. Tripeptide Interference with Human Immunodeficiency Virus Type 1 Morphogenesis
  172. A hybrid microdevice for electrophoresis and electrochromatography using UV detection
  173. Stable homogeneous gel for molecular-sieving of DNA fragments in capillary electrophoresis
  174. Enantioseparation of hydroxy acids on easy-to-prepare continuous beds for capillary electrochromatography
  175. Chiral separation of amino acids by ligand-exchange capillary electrochromatography using continuous beds
  176. A new easy-to-prepare homogeneous continuous electrochromatographic bed for enantiomer recognition
  177. A new easy-to-prepare homogeneous continuous electrochromatographic bed for enantiomer recognition
  178. Chiral separation of amino acids by ligand-exchange capillary electrochromatography using continuous beds
  179. (Normal-phase) capillary chromatography using acrylic polymer-based continuous beds
  180. Chiral separation of α-amino acids by ligand-exchange capillary electrophoresis usingN-(2-hydroxy-octyl)-L-4-hydroxyproline as a selector
  181. New set-up for capillary isoelectric focusing in uncoated capillaries