All Stories

  1. Lysine methyltransferase SET7 links cardiometabolic risk to endothelial dysfunction by dysregulating mRNA splicing and eNOS-CaM interaction
  2. In‐Vitro Evaluation of HIV/SARS‐CoV‐2 Co‐Infection Mediated Proteomic Changes in Astrocytes and Pericytes Reveals Altered Signaling Pathways Associated With Neurodegenerative Disorders
  3. Small molecule inhibition of voltage dependent anion channel 1 reroutes mitochondrial metabolite flux
  4. Multi-omics uncovers interaction in the vaginal microbiome and a type II secretion/Tad pilus system in Gardnerella vaginalis
  5. Klebsiella pneumoniae LPS drives stromal-mediated repression of p53 and colorectal cancer chemoresistance
  6. MitoSAM-dependent lipoylation controls postnatal heart development via metabolic remodeling
  7. Metabolic Reprogramming and Tunneling Nanotubes Cooperate to Regulate HIV-1 Latency Reactivation
  8. Acute high-dose irradiation disrupts cell adhesion and Silk-Ovarioid formation in human primary ovarian cells
  9. Profiling of Extracellular Vesicles of Non‐Small Cell Lung Cancer Reveals Proteins Associated With Osimertinib Resistance
  10. Pharmacological activation of p53 induces dose-dependent changes in endothelial cell fate during angiogenic sprouting
  11. Autoimmunity-associated DIORA1 binds the MRCK family of serine/threonine kinases and controls cell motility
  12. Toward a Species Search Engine: KISSE Offers a Rigorous Statistical Framework for Bone Collagen Tandem Mass Spectrometry Data
  13. Changes in circulating extracellular vesicle cargo are associated with cognitive decline after major surgery: an observational case–control study
  14. The Temporal Dynamics of Proteins in Aged Skin Wound Healing and Comparison with Gene Expression
  15. Comprehensive analysis of multi‐omics single‐cell data using the single‐cell analyst
  16. Collaborative Duality of CircGLIS3(2) RNA and Protein in human Wound Repair
  17. Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
  18. Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
  19. The proteome of osteoblasts in a 3D culture perfusion bioreactor model compared with static conditions
  20. Towards a species search engine: KISSE offers a rigorous statistical framework for bone collagen tandem mass spectrometry data
  21. Erythrocyte-derived extracellular vesicles induce endothelial dysfunction through arginase-1 and oxidative stress in type 2 diabetes
  22. Acute high-dose irradiation of human primary ovarian cells reveals a shift in transcriptomics profile and impairment in cell-cell adhesion
  23. Proteomic analysis reveals biomarkers associated with performance-based joint function and patient-reported outcomes in knee osteoarthritis
  24. Host Plasma Microenvironment in Immunometabolically Impaired HIV Infection Leads to Dysregulated Monocyte Function and Synaptic Transmission Ex Vivo
  25. Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
  26. The di-leucine motif in the host defense peptide LL-37 is essential for initiation of autophagy in human macrophages
  27. Silk-Ovarioids: establishment and characterization of a human ovarian primary cell 3D-model system
  28. SARS-CoV-2 variants mediated tissue-specific metabolic reprogramming determines the disease pathophysiology in a hamster model
  29. Characterization of the HLA-DR immunopeptidome of bronchoalveolar lavage cells in patients with newly diagnosed rheumatoid arthritis and healthy current-smoker controls
  30. Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
  31. microRNA and non-targeted proteome analysis of liquid biopsies from the distal lung collected by Particles in Exhaled Air (PExA) reveals presence from extracellular vesicles
  32. Bacterial extracellular vesicles as intranasal postbiotics: Detailed characterization and interaction with airway cells
  33. Mouse PAW: reverse-translating the FINGER multimodal lifestyle intervention enhances synaptic plasticity and cognition in adult wild type female mice
  34. Gel-Assisted Proteome Position Integral Shift Assay Returns Molecular Weight to Shotgun Proteomics and Identifies Caspase 3 Substrates
  35. Silk-Ovarioids: Establishment and characterization of human ovarian primary cells 3D-model system
  36. Network analysis reveals age‐ and virus‐specific circuits in nasal epithelial cells of extremely premature infants
  37. A multi-platform analysis of human gingival crevicular fluid reveals ferroptosis as a relevant regulated cell death mechanism during the clinical progression of periodontitis
  38. Abstract 5138: Proteomic analyses of the urothelial cancer landscape reveal highly distinct prognostic and predictive subtypes
  39. TISSUE-SPECIFIC METABOLOMIC REPROGRAMMING DETERMINES THE DISEASE PATHOPHYSIOLOGY OF SARS-COV-2 VARIANTS IN HAMSTER MODEL
  40. Gel-Assisted Proteome Position Integral Shift (GAPPIS) Assay Returns Molecular Weight to Shotgun Proteomics and Identifies Novel Caspase 3 Substrates
  41. 3D microperfusion of mesoscale human microphysiological liver models improves functionality and recapitulates hepatic zonation
  42. Toward Single Bacterium Proteomics
  43. Multifaceted proteome analysis at solubility, redox, and expression dimensions for target identification
  44. Analysis of local extracellular matrix identifies different aetiologies behind bicuspid and tricuspid aortic valve degeneration and suggests therapies
  45. Proteomic profile of human gingival crevicular fluid reveals specific biological and molecular processes during clinical progression of periodontitis
  46. Non-typeable Haemophilus influenzae major outer membrane protein P5 contributes to bacterial membrane stability, and affects the membrane protein composition crucial for interactions with the human host
  47. Distribution, cellular localization, and colocalization of several peptide neurotransmitters in the central nervous system ofAplysia
  48. Naturally occurring dipeptide from elite controllers with dual anti-HIV-1 mechanism
  49. NCF1-dependent production of ROS protects against lupus by regulating plasmacytoid dendritic cell development and functions
  50. Genomic adaptation underlies nutrient-driven reprogramming in the malaria-causing parasite
  51. Brain endothelial cells exposure to malaria parasites links type I interferon signalling to antigen presentation, immunoproteasome activation, endothelium disruption, and cellular metabolism
  52. Panomics reveals patient individuality as the major driver of colorectal cancer progression
  53. Impaired Immuno-Metabolic Homeostasis and Microenvironmental Influence on Neuropsychiatric Risk in Treated HIV Infection
  54. Brain endothelial cells exposure to malaria parasites links Type I interferon signalling to antigen presentation, immunoproteasome activation, endothelium disruption and cell metabolic adaptation
  55. Plasma proteomic profiling in postural orthostatic tachycardia syndrome (POTS) reveals new disease pathways
  56. Panomics reveals patient-individuality as the major driver for colorectal cancer progression
  57. Mapping the GALNT1 substrate landscape with versatile proteomics tools
  58. Single-Cell Chemical Proteomics (SCCP) Interrogates the Timing and Heterogeneity of Cancer Cell Commitment to Death
  59. Mass Spectrometry, Structural Analysis, and Anti-Inflammatory Properties of Photo-Cross-Linked Human Albumin Hydrogels
  60. Hepatocyte Thorns, A Novel Drug-Induced Stress Response in Human and Mouse Liver Spheroids
  61. Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target
  62. Peripheral blood CD4+CCR6+ compartment differentiates HIV-1 infected or seropositive elite controllers from long-term successfully treated individuals
  63. Epigenetic modulators link mitochondrial redox homeostasis to cardiac function
  64. Author response: Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target
  65. Nucleoside-Modified mRNA Vaccines Protect IFNAR –/– Mice against Crimean-Congo Hemorrhagic Fever Virus Infection
  66. Trans cohort metabolic reprogramming towards glutaminolysis in long-term successfully treated HIV-infection
  67. Integrative proteo-transcriptomic and immunophenotyping signatures of HIV-1 elite control phenotype: A cross-talk between glycolysis and HIF signaling
  68. Mass Spectrometry-Based Analytical Strategy for Single-Cell Proteomics
  69. Ultralight ultrafast enzymes
  70. Peripheral blood CD4+CCR6+ compartment differentiates HIV-1 infected or seropositive elite controllers from long-term successfully treated individuals
  71. Single Cell Proteomics Using Multiplexed Isobaric Labeling for Mass Spectrometric Analysis
  72. Citrullination Alters the Antibacterial and Anti-Inflammatory Functions of the Host Defense Peptide Canine Cathelicidin K9CATH In Vitro
  73. Trans Cohorts Metabolomic Modulation Following Long-Term Successful Therapy in HIV-Infection
  74. Coordinated pyruvate kinase activity is crucial for metabolic adaptation and cell survival during mitochondrial dysfunction
  75. Type-I interferon signatures in SARS-CoV-2 infected Huh7 cells
  76. Longitudinal blood cell transcriptomic profiling and in vitro temporal proteomics provides novel insights into metabolic reprogramming and host-immune responses against Crimean-Congo Hemorrhagic Fever Virus
  77. Cell-type-resolved quantitative proteomics map of interferon response against SARS-CoV-2
  78. Single Cell Chemical Proteomics (SCCP) Interrogates the Timing and Heterogeneity of Cancer Cell Commitment to Death
  79. Cytotoxic Lymphocytes Target HIV-1 Gag Through Granzyme M-Mediated Cleavage
  80. EPHA2 Interacts with DNA-PKcs in Cell Nucleus and Controls Ionizing Radiation Responses in Non-Small Cell Lung Cancer Cells
  81. System-wide identification and prioritization of enzyme substrates by thermal analysis
  82. The one-carbon pool controls mitochondrial energy metabolism via complex I and iron-sulfur clusters
  83. Metabolic Perturbation Associated With COVID-19 Disease Severity and SARS-CoV-2 Replication
  84. Single Cell Chemical Proteomics (SCCP) Interrogates the Timing and Heterogeneity of Cancer Cell Commitment to Death
  85. Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo Hemorrhagic Fever Viruses for novel therapeutic target
  86. Utility of Proteomics in Emerging and Re-Emerging Infectious Diseases Caused by RNA Viruses
  87. Mutant Proteomics of Lung Adenocarcinomas Harboring Different EGFR Mutations
  88. Correction: S100A6 is a critical regulator of hematopoietic stem cells
  89. S100A6 is a critical regulator of hematopoietic stem cells
  90. Dysregulation in mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells
  91. Studies on citrullinated LL-37: detection in human airways, antibacterial effects and biophysical properties
  92. Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells
  93. ProTargetMiner as a proteome signature library of anticancer molecules for functional discovery
  94. Current status of clinical proteogenomics in lung cancer
  95. Malondialdehyde Conjugated With Albumin Induces Pro-Inflammatory Activation of T Cells Isolated From Human Atherosclerotic Plaques Both Directly and Via Dendritic Cell–Mediated Mechanism
  96. System-wide identification and prioritization of enzyme substrates by thermal analysis (SIESTA)
  97. ProTargetMiner: A proteome signature library of anticancer molecules for functional discovery
  98. Deuteration of human carbonic anhydrase for neutron crystallography: Cell culture media, protein thermostability, and crystallization behavior
  99. Large Scale Identification of Variant Proteins in Glioma Stem Cells
  100. In vivo Distribution of Tiotropium in a Rodent Model Utilizing AP-SMALDI Mass Spectrometry Imaging
  101. Limited Tumor Tissue Drug Penetration Contributes to Primary Resistance against Angiogenesis Inhibitors
  102. Relationship between HMF intake and SMF formation in vivo: An animal and human study
  103. Localization of tamoxifen in human breast cancer tumors by MALDI mass spectrometry imaging
  104. Novel insights in drug metabolism by MS imaging
  105. Mutant Proteogenomics
  106. Proteogenomics
  107. Drug localizations in tissue by mass spectrometry imaging
  108. In Vitro Transcription/Translation System: A Versatile Tool in the Search for Missing Proteins
  109. Drug compound characterization by mass spectrometry imaging in cancer tissue
  110. Quest for Missing Proteins: Update 2015 on Chromosome-Centric Human Proteome Project
  111. Erratum to: Association of chromosome 19 to lung cancer genotypes and phenotypes
  112. Association of chromosome 19 to lung cancer genotypes and phenotypes
  113. Localization of sunitinib, its metabolites and its target receptors in tumour-bearing mice: a MALDI-MS imaging study
  114. Localization of sunitinib in in vivo animal and in vitro experimental models by MALDI mass spectrometry imaging
  115. Use of ENCODE Resources to Characterize Novel Proteoforms and Missing Proteins in the Human Proteome
  116. Systematic Identification of Single Amino Acid Variants in Glioma Stem-Cell-Derived Chromosome 19 Proteins
  117. SC-23 * THE ROLE OF SINGLE AMINO ACID POLYMORPHISMS IN GLIOMA STEM CELL PHENOTYPES
  118. A new look at drugs targeting malignant melanoma-An application for mass spectrometry imaging
  119. Aptamer/ISET-MS: A New Affinity-Based MALDI Technique for Improved Detection of Biomarkers
  120. Inflammatory markers in Huntington's disease plasma—A robust nanoLC–MRM-MS assay development
  121. Queries of MALDI-imaging global datasets identifying ion mass signatures associated with tissue compartments
  122. Identification of Missing Proteins: Toward the Completion of Human Proteome
  123. Integrated Chromosome 19 Transcriptomic and Proteomic Data Sets Derived from Glioma Cancer Stem-Cell Lines
  124. Developments in biobanking workflow standardization providing sample integrity and stability
  125. Experimental Models to Study Drug Distributions in Tissue Using MALDI Mass Spectrometry Imaging
  126. Accessing microenvironment compartments in formalin-fixed paraffin-embedded tissues by protein expression analysis
  127. Quantification of Human Kallikrein-2 in Clinical Samples by Selected Reaction Monitoring
  128. Identification of a Novel Proteoform of Prostate Specific Antigen (SNP-L132I) in Clinical Samples by Multiple Reaction Monitoring
  129. Development of an MRM assay panel with application to biobank samples from patients with myocardial infarction
  130. Blood Plasma Reference Material: A Global Resource for Proteomic Research
  131. Correlation Queries for Mass Spectrometry Imaging
  132. Establishing a Southern Swedish Malignant Melanoma OMICS and biobank clinical capability
  133. International biobanking for lung cancer and COPD as the future resource for clinical protein research
  134. Standardization developments for large scale biobanks in smoking related diseases - a model system for blood sample processing and storage
  135. A Critical Evaluation of Inflammatory Markers in Huntington's Disease Plasma
  136. Clinical and Biomedical Mass Spectrometry: New Frontiers in Drug Developments and Diagnosis
  137. Chromosome 19 Annotations with Disease Speciation: A First Report from the Global Research Consortium
  138. Large scale biobanking of blood — The importance of high density sample processing procedures
  139. Standardization and Utilization of Biobank Resources in Clinical Protein Science with Examples of Emerging Applications
  140. Molecular microheterogeneity of prostate specific antigen in seminal fluid by mass spectrometry
  141. Cancer Phenotype Diagnosis and Drug Efficacy within Japanese Health Care
  142. Clinical Proteomics
  143. Understanding drug uptake and binding within targeted disease micro-environments in patients: a new tool for translational medicine
  144. Bioinformatic strategies for unambiguous identification of prostate specific antigen in clinical samples
  145. MRM assay for quantitation of complement components in human blood plasma — a feasibility study on multiple sclerosis
  146. State-of-the-art MS technology applications in lung disease
  147. Direct Demonstration of Tissue Uptake of an Inhaled Drug: Proof-of-Principle Study Using Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging
  148. Drug localization in different lung cancer phenotypes by MALDI mass spectrometry imaging
  149. Biobank resources for future patient care: developments, principles and concepts
  150. Moving towards high density clinical signature studies with a human proteome catalogue developing multiplexing mass spectrometry assay panels
  151. Clinical Protein Science and Bioanalytical Mass Spectrometry with an Emphasis on Lung Cancer
  152. Essential tactics of tissue preparation and matrix nano-spotting for successful compound imaging mass spectrometry
  153. Identification of prostate-specific antigen (PSA) isoforms in complex biological samples utilizing complementary platforms
  154. Isotope labeled internal standards (ILIS) as a basis for quality control in clinical studies using plasma samples
  155. Multiple sclerosis: Identification and clinical evaluation of novel CSF biomarkers
  156. Determination of dissociation constants between polyelectrolytes and proteins by affinity capillary electrophoresis
  157. Identification of novel candidate protein biomarkers for the post-polio syndrome — Implications for diagnosis, neurodegeneration and neuroinflammation
  158. General Approach for Certain Quantitative Calculations for Instance of the Variance of Reversible Adsorption to the Capillary Wall in CE
  159. Isolation and characterization of a small antiretroviral molecule affecting HIV-1 capsid morphology
  160. Activity of the Small Modified Amino Acid α-Hydroxy Glycineamide on In Vitro and In Vivo Human Immunodeficiency Virus Type 1 Capsid Assembly and Infectivity
  161. Implementation of a protein profiling platform developed as an academic‐pharmaceutical industry collaborative effort
  162. Universal method for synthesis of artificial gel antibodies by the imprinting approach combined with a unique electrophoresis technique for detection of minute structural differences of proteins, viruses and cells (bacteria). Ib. Gel antibodies against...
  163. Universal method for synthesis of artificial gel antibodies by the imprinting approach combined with a unique electrophoresis technique for detection of minute structural differences of proteins, viruses, and cells (bacteria). III: Gel antibodies again...
  164. Theoretical and nomenclatural considerations of capillary electrochromatography with monolithic stationary phases
  165. Vitamin D receptor gene polymorphism in rheumatoid arthritis and associated osteoporosis
  166. Homogeneous gels for capillary electrochromatography
  167. T-cell recognition of differentially tolerated epitopes of cartilage proteoglycan aggrecan in arthritis
  168. Chapter 10 Technologies interfacing capillary electrophoresis to mass spectrometry
  169. Chapter 3 Peptide and protein separations by capillary electrophoresis and electrochromatography
  170. 2 Evolution and development of isoelectric focusing
  171. Hybrid microdevice electrophoresis of peptides, proteins, DNA, viruses, and bacteria in various separation media, using UV-detection
  172. High-Resolution Capillary Zone and Gel Electrophoresis of Structurally Similar Amphipathic Glutathione Conjugates Based on Interaction with -Cyclodextrins
  173. Tripeptide Interference with Human Immunodeficiency Virus Type 1 Morphogenesis
  174. A hybrid microdevice for electrophoresis and electrochromatography using UV detection
  175. Stable homogeneous gel for molecular-sieving of DNA fragments in capillary electrophoresis
  176. Enantioseparation of hydroxy acids on easy-to-prepare continuous beds for capillary electrochromatography
  177. Chiral separation of amino acids by ligand-exchange capillary electrochromatography using continuous beds
  178. A new easy-to-prepare homogeneous continuous electrochromatographic bed for enantiomer recognition
  179. A new easy-to-prepare homogeneous continuous electrochromatographic bed for enantiomer recognition
  180. Chiral separation of amino acids by ligand-exchange capillary electrochromatography using continuous beds
  181. (Normal-phase) capillary chromatography using acrylic polymer-based continuous beds
  182. Chiral separation of α-amino acids by ligand-exchange capillary electrophoresis usingN-(2-hydroxy-octyl)-L-4-hydroxyproline as a selector
  183. New set-up for capillary isoelectric focusing in uncoated capillaries