All Stories

  1. Plasma Proteomic Profiling Reveals Alterations in Coagulation, Complement, and Extracellular Matrix Pathways in Orthostatic Hypotension
  2. Loss of the mitochondrial SAM transporter reveals a lipoylation-dependent metabolic vulnerability in the postnatal heart
  3. Transcriptional Regulator FabR Is Associated With the Virulence of Non-Typeable Haemophilus Influenzae in Host–Pathogen Interactions
  4. Lysine methyltransferase SET7 links cardiometabolic risk to endothelial dysfunction by dysregulating mRNA splicing and eNOS-CaM interaction
  5. In‐Vitro Evaluation of HIV/SARS‐CoV‐2 Co‐Infection Mediated Proteomic Changes in Astrocytes and Pericytes Reveals Altered Signaling Pathways Associated With Neurodegenerative Disorders
  6. Small molecule inhibition of voltage dependent anion channel 1 reroutes mitochondrial metabolite flux
  7. Multi-omics uncovers interaction in the vaginal microbiome and a type II secretion/Tad pilus system in Gardnerella vaginalis
  8. Klebsiella pneumoniae LPS drives stromal-mediated repression of p53 and colorectal cancer chemoresistance
  9. MitoSAM-dependent lipoylation controls postnatal heart development via metabolic remodeling
  10. Metabolic Reprogramming and Tunneling Nanotubes Cooperate to Regulate HIV-1 Latency Reactivation
  11. Acute high-dose irradiation disrupts cell adhesion and Silk-Ovarioid formation in human primary ovarian cells
  12. Profiling of Extracellular Vesicles of Non‐Small Cell Lung Cancer Reveals Proteins Associated With Osimertinib Resistance
  13. Pharmacological activation of p53 induces dose-dependent changes in endothelial cell fate during angiogenic sprouting
  14. Autoimmunity-associated DIORA1 binds the MRCK family of serine/threonine kinases and controls cell motility
  15. Toward a Species Search Engine: KISSE Offers a Rigorous Statistical Framework for Bone Collagen Tandem Mass Spectrometry Data
  16. Changes in circulating extracellular vesicle cargo are associated with cognitive decline after major surgery: an observational case–control study
  17. The Temporal Dynamics of Proteins in Aged Skin Wound Healing and Comparison with Gene Expression
  18. Comprehensive analysis of multi‐omics single‐cell data using the single‐cell analyst
  19. Collaborative Duality of CircGLIS3(2) RNA and Protein in human Wound Repair
  20. Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
  21. Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
  22. The proteome of osteoblasts in a 3D culture perfusion bioreactor model compared with static conditions
  23. Towards a species search engine: KISSE offers a rigorous statistical framework for bone collagen tandem mass spectrometry data
  24. Erythrocyte-derived extracellular vesicles induce endothelial dysfunction through arginase-1 and oxidative stress in type 2 diabetes
  25. Acute high-dose irradiation of human primary ovarian cells reveals a shift in transcriptomics profile and impairment in cell-cell adhesion
  26. Proteomic analysis reveals biomarkers associated with performance-based joint function and patient-reported outcomes in knee osteoarthritis
  27. Host Plasma Microenvironment in Immunometabolically Impaired HIV Infection Leads to Dysregulated Monocyte Function and Synaptic Transmission Ex Vivo
  28. Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
  29. The di-leucine motif in the host defense peptide LL-37 is essential for initiation of autophagy in human macrophages
  30. Silk-Ovarioids: establishment and characterization of a human ovarian primary cell 3D-model system
  31. SARS-CoV-2 variants mediated tissue-specific metabolic reprogramming determines the disease pathophysiology in a hamster model
  32. Characterization of the HLA-DR immunopeptidome of bronchoalveolar lavage cells in patients with newly diagnosed rheumatoid arthritis and healthy current-smoker controls
  33. Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
  34. microRNA and non-targeted proteome analysis of liquid biopsies from the distal lung collected by Particles in Exhaled Air (PExA) reveals presence from extracellular vesicles
  35. Bacterial extracellular vesicles as intranasal postbiotics: Detailed characterization and interaction with airway cells
  36. Mouse PAW: reverse-translating the FINGER multimodal lifestyle intervention enhances synaptic plasticity and cognition in adult wild type female mice
  37. Gel-Assisted Proteome Position Integral Shift Assay Returns Molecular Weight to Shotgun Proteomics and Identifies Caspase 3 Substrates
  38. Silk-Ovarioids: Establishment and characterization of human ovarian primary cells 3D-model system
  39. Network analysis reveals age‐ and virus‐specific circuits in nasal epithelial cells of extremely premature infants
  40. A multi-platform analysis of human gingival crevicular fluid reveals ferroptosis as a relevant regulated cell death mechanism during the clinical progression of periodontitis
  41. Abstract 5138: Proteomic analyses of the urothelial cancer landscape reveal highly distinct prognostic and predictive subtypes
  42. TISSUE-SPECIFIC METABOLOMIC REPROGRAMMING DETERMINES THE DISEASE PATHOPHYSIOLOGY OF SARS-COV-2 VARIANTS IN HAMSTER MODEL
  43. Gel-Assisted Proteome Position Integral Shift (GAPPIS) Assay Returns Molecular Weight to Shotgun Proteomics and Identifies Novel Caspase 3 Substrates
  44. 3D microperfusion of mesoscale human microphysiological liver models improves functionality and recapitulates hepatic zonation
  45. Toward Single Bacterium Proteomics
  46. Multifaceted proteome analysis at solubility, redox, and expression dimensions for target identification
  47. Analysis of local extracellular matrix identifies different aetiologies behind bicuspid and tricuspid aortic valve degeneration and suggests therapies
  48. Proteomic profile of human gingival crevicular fluid reveals specific biological and molecular processes during clinical progression of periodontitis
  49. Non-typeable Haemophilus influenzae major outer membrane protein P5 contributes to bacterial membrane stability, and affects the membrane protein composition crucial for interactions with the human host
  50. Distribution, cellular localization, and colocalization of several peptide neurotransmitters in the central nervous system ofAplysia
  51. Naturally occurring dipeptide from elite controllers with dual anti-HIV-1 mechanism
  52. NCF1-dependent production of ROS protects against lupus by regulating plasmacytoid dendritic cell development and functions
  53. Genomic adaptation underlies nutrient-driven reprogramming in the malaria-causing parasite
  54. Brain endothelial cells exposure to malaria parasites links type I interferon signalling to antigen presentation, immunoproteasome activation, endothelium disruption, and cellular metabolism
  55. Panomics reveals patient individuality as the major driver of colorectal cancer progression
  56. Impaired Immuno-Metabolic Homeostasis and Microenvironmental Influence on Neuropsychiatric Risk in Treated HIV Infection
  57. Brain endothelial cells exposure to malaria parasites links Type I interferon signalling to antigen presentation, immunoproteasome activation, endothelium disruption and cell metabolic adaptation
  58. Plasma proteomic profiling in postural orthostatic tachycardia syndrome (POTS) reveals new disease pathways
  59. Panomics reveals patient-individuality as the major driver for colorectal cancer progression
  60. Mapping the GALNT1 substrate landscape with versatile proteomics tools
  61. Single-Cell Chemical Proteomics (SCCP) Interrogates the Timing and Heterogeneity of Cancer Cell Commitment to Death
  62. Mass Spectrometry, Structural Analysis, and Anti-Inflammatory Properties of Photo-Cross-Linked Human Albumin Hydrogels
  63. Hepatocyte Thorns, A Novel Drug-Induced Stress Response in Human and Mouse Liver Spheroids
  64. Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target
  65. Peripheral blood CD4+CCR6+ compartment differentiates HIV-1 infected or seropositive elite controllers from long-term successfully treated individuals
  66. Epigenetic modulators link mitochondrial redox homeostasis to cardiac function
  67. Author response: Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target
  68. Nucleoside-Modified mRNA Vaccines Protect IFNAR –/– Mice against Crimean-Congo Hemorrhagic Fever Virus Infection
  69. Trans cohort metabolic reprogramming towards glutaminolysis in long-term successfully treated HIV-infection
  70. Integrative proteo-transcriptomic and immunophenotyping signatures of HIV-1 elite control phenotype: A cross-talk between glycolysis and HIF signaling
  71. Mass Spectrometry-Based Analytical Strategy for Single-Cell Proteomics
  72. Ultralight ultrafast enzymes
  73. Peripheral blood CD4+CCR6+ compartment differentiates HIV-1 infected or seropositive elite controllers from long-term successfully treated individuals
  74. Single Cell Proteomics Using Multiplexed Isobaric Labeling for Mass Spectrometric Analysis
  75. Citrullination Alters the Antibacterial and Anti-Inflammatory Functions of the Host Defense Peptide Canine Cathelicidin K9CATH In Vitro
  76. Trans Cohorts Metabolomic Modulation Following Long-Term Successful Therapy in HIV-Infection
  77. Coordinated pyruvate kinase activity is crucial for metabolic adaptation and cell survival during mitochondrial dysfunction
  78. Type-I interferon signatures in SARS-CoV-2 infected Huh7 cells
  79. Longitudinal blood cell transcriptomic profiling and in vitro temporal proteomics provides novel insights into metabolic reprogramming and host-immune responses against Crimean-Congo Hemorrhagic Fever Virus
  80. Cell-type-resolved quantitative proteomics map of interferon response against SARS-CoV-2
  81. Single Cell Chemical Proteomics (SCCP) Interrogates the Timing and Heterogeneity of Cancer Cell Commitment to Death
  82. Cytotoxic Lymphocytes Target HIV-1 Gag Through Granzyme M-Mediated Cleavage
  83. EPHA2 Interacts with DNA-PKcs in Cell Nucleus and Controls Ionizing Radiation Responses in Non-Small Cell Lung Cancer Cells
  84. System-wide identification and prioritization of enzyme substrates by thermal analysis
  85. The one-carbon pool controls mitochondrial energy metabolism via complex I and iron-sulfur clusters
  86. Metabolic Perturbation Associated With COVID-19 Disease Severity and SARS-CoV-2 Replication
  87. Single Cell Chemical Proteomics (SCCP) Interrogates the Timing and Heterogeneity of Cancer Cell Commitment to Death
  88. Integrative Proteo-Transcriptomic and Immunophenotyping Signatures of HIV-1 Elite Control Phenotype: A Cross-Talk Between Glycolysis and HIF Signaling
  89. Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo Hemorrhagic Fever Viruses for novel therapeutic target
  90. Utility of Proteomics in Emerging and Re-Emerging Infectious Diseases Caused by RNA Viruses
  91. Mutant Proteomics of Lung Adenocarcinomas Harboring Different EGFR Mutations
  92. Correction: S100A6 is a critical regulator of hematopoietic stem cells
  93. S100A6 is a critical regulator of hematopoietic stem cells
  94. Dysregulation in mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells
  95. Studies on citrullinated LL-37: detection in human airways, antibacterial effects and biophysical properties
  96. Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells
  97. ProTargetMiner as a proteome signature library of anticancer molecules for functional discovery
  98. Current status of clinical proteogenomics in lung cancer
  99. Malondialdehyde Conjugated With Albumin Induces Pro-Inflammatory Activation of T Cells Isolated From Human Atherosclerotic Plaques Both Directly and Via Dendritic Cell–Mediated Mechanism
  100. System-wide identification and prioritization of enzyme substrates by thermal analysis (SIESTA)
  101. ProTargetMiner: A proteome signature library of anticancer molecules for functional discovery
  102. Deuteration of human carbonic anhydrase for neutron crystallography: Cell culture media, protein thermostability, and crystallization behavior
  103. Large Scale Identification of Variant Proteins in Glioma Stem Cells
  104. In vivo Distribution of Tiotropium in a Rodent Model Utilizing AP-SMALDI Mass Spectrometry Imaging
  105. Limited Tumor Tissue Drug Penetration Contributes to Primary Resistance against Angiogenesis Inhibitors
  106. Relationship between HMF intake and SMF formation in vivo: An animal and human study
  107. Localization of tamoxifen in human breast cancer tumors by MALDI mass spectrometry imaging
  108. Novel insights in drug metabolism by MS imaging
  109. Mutant Proteogenomics
  110. Proteogenomics
  111. Drug localizations in tissue by mass spectrometry imaging
  112. In Vitro Transcription/Translation System: A Versatile Tool in the Search for Missing Proteins
  113. Drug compound characterization by mass spectrometry imaging in cancer tissue
  114. Quest for Missing Proteins: Update 2015 on Chromosome-Centric Human Proteome Project
  115. Erratum to: Association of chromosome 19 to lung cancer genotypes and phenotypes
  116. Association of chromosome 19 to lung cancer genotypes and phenotypes
  117. Localization of sunitinib, its metabolites and its target receptors in tumour-bearing mice: a MALDI-MS imaging study
  118. Localization of sunitinib in in vivo animal and in vitro experimental models by MALDI mass spectrometry imaging
  119. Use of ENCODE Resources to Characterize Novel Proteoforms and Missing Proteins in the Human Proteome
  120. Systematic Identification of Single Amino Acid Variants in Glioma Stem-Cell-Derived Chromosome 19 Proteins
  121. SC-23 * THE ROLE OF SINGLE AMINO ACID POLYMORPHISMS IN GLIOMA STEM CELL PHENOTYPES
  122. A new look at drugs targeting malignant melanoma-An application for mass spectrometry imaging
  123. Aptamer/ISET-MS: A New Affinity-Based MALDI Technique for Improved Detection of Biomarkers
  124. Inflammatory markers in Huntington's disease plasma—A robust nanoLC–MRM-MS assay development
  125. Queries of MALDI-imaging global datasets identifying ion mass signatures associated with tissue compartments
  126. Identification of Missing Proteins: Toward the Completion of Human Proteome
  127. Integrated Chromosome 19 Transcriptomic and Proteomic Data Sets Derived from Glioma Cancer Stem-Cell Lines
  128. Developments in biobanking workflow standardization providing sample integrity and stability
  129. Experimental Models to Study Drug Distributions in Tissue Using MALDI Mass Spectrometry Imaging
  130. Accessing microenvironment compartments in formalin-fixed paraffin-embedded tissues by protein expression analysis
  131. Quantification of Human Kallikrein-2 in Clinical Samples by Selected Reaction Monitoring
  132. Identification of a Novel Proteoform of Prostate Specific Antigen (SNP-L132I) in Clinical Samples by Multiple Reaction Monitoring
  133. Development of an MRM assay panel with application to biobank samples from patients with myocardial infarction
  134. Blood Plasma Reference Material: A Global Resource for Proteomic Research
  135. Correlation Queries for Mass Spectrometry Imaging
  136. Establishing a Southern Swedish Malignant Melanoma OMICS and biobank clinical capability
  137. International biobanking for lung cancer and COPD as the future resource for clinical protein research
  138. Standardization developments for large scale biobanks in smoking related diseases - a model system for blood sample processing and storage
  139. A Critical Evaluation of Inflammatory Markers in Huntington's Disease Plasma
  140. Clinical and Biomedical Mass Spectrometry: New Frontiers in Drug Developments and Diagnosis
  141. Chromosome 19 Annotations with Disease Speciation: A First Report from the Global Research Consortium
  142. Large scale biobanking of blood — The importance of high density sample processing procedures
  143. Standardization and Utilization of Biobank Resources in Clinical Protein Science with Examples of Emerging Applications
  144. Molecular microheterogeneity of prostate specific antigen in seminal fluid by mass spectrometry
  145. Cancer Phenotype Diagnosis and Drug Efficacy within Japanese Health Care
  146. Clinical Proteomics
  147. Understanding drug uptake and binding within targeted disease micro-environments in patients: a new tool for translational medicine
  148. Bioinformatic strategies for unambiguous identification of prostate specific antigen in clinical samples
  149. MRM assay for quantitation of complement components in human blood plasma — a feasibility study on multiple sclerosis
  150. State-of-the-art MS technology applications in lung disease
  151. Direct Demonstration of Tissue Uptake of an Inhaled Drug: Proof-of-Principle Study Using Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging
  152. Drug localization in different lung cancer phenotypes by MALDI mass spectrometry imaging
  153. Biobank resources for future patient care: developments, principles and concepts
  154. Moving towards high density clinical signature studies with a human proteome catalogue developing multiplexing mass spectrometry assay panels
  155. Clinical Protein Science and Bioanalytical Mass Spectrometry with an Emphasis on Lung Cancer
  156. Essential tactics of tissue preparation and matrix nano-spotting for successful compound imaging mass spectrometry
  157. Identification of prostate-specific antigen (PSA) isoforms in complex biological samples utilizing complementary platforms
  158. Isotope labeled internal standards (ILIS) as a basis for quality control in clinical studies using plasma samples
  159. Multiple sclerosis: Identification and clinical evaluation of novel CSF biomarkers
  160. Determination of dissociation constants between polyelectrolytes and proteins by affinity capillary electrophoresis
  161. Identification of novel candidate protein biomarkers for the post-polio syndrome — Implications for diagnosis, neurodegeneration and neuroinflammation
  162. General Approach for Certain Quantitative Calculations for Instance of the Variance of Reversible Adsorption to the Capillary Wall in CE
  163. Isolation and characterization of a small antiretroviral molecule affecting HIV-1 capsid morphology
  164. Activity of the Small Modified Amino Acid α-Hydroxy Glycineamide on In Vitro and In Vivo Human Immunodeficiency Virus Type 1 Capsid Assembly and Infectivity
  165. Implementation of a protein profiling platform developed as an academic‐pharmaceutical industry collaborative effort
  166. Universal method for synthesis of artificial gel antibodies by the imprinting approach combined with a unique electrophoresis technique for detection of minute structural differences of proteins, viruses and cells (bacteria). Ib. Gel antibodies against...
  167. Universal method for synthesis of artificial gel antibodies by the imprinting approach combined with a unique electrophoresis technique for detection of minute structural differences of proteins, viruses, and cells (bacteria). III: Gel antibodies again...
  168. Theoretical and nomenclatural considerations of capillary electrochromatography with monolithic stationary phases
  169. Vitamin D receptor gene polymorphism in rheumatoid arthritis and associated osteoporosis
  170. Homogeneous gels for capillary electrochromatography
  171. T-cell recognition of differentially tolerated epitopes of cartilage proteoglycan aggrecan in arthritis
  172. Chapter 10 Technologies interfacing capillary electrophoresis to mass spectrometry
  173. Chapter 3 Peptide and protein separations by capillary electrophoresis and electrochromatography
  174. 2 Evolution and development of isoelectric focusing
  175. Hybrid microdevice electrophoresis of peptides, proteins, DNA, viruses, and bacteria in various separation media, using UV-detection
  176. High-Resolution Capillary Zone and Gel Electrophoresis of Structurally Similar Amphipathic Glutathione Conjugates Based on Interaction with -Cyclodextrins
  177. Tripeptide Interference with Human Immunodeficiency Virus Type 1 Morphogenesis
  178. A hybrid microdevice for electrophoresis and electrochromatography using UV detection
  179. Stable homogeneous gel for molecular-sieving of DNA fragments in capillary electrophoresis
  180. Enantioseparation of hydroxy acids on easy-to-prepare continuous beds for capillary electrochromatography
  181. Chiral separation of amino acids by ligand-exchange capillary electrochromatography using continuous beds
  182. A new easy-to-prepare homogeneous continuous electrochromatographic bed for enantiomer recognition
  183. A new easy-to-prepare homogeneous continuous electrochromatographic bed for enantiomer recognition
  184. Chiral separation of amino acids by ligand-exchange capillary electrochromatography using continuous beds
  185. (Normal-phase) capillary chromatography using acrylic polymer-based continuous beds
  186. Chiral separation of α-amino acids by ligand-exchange capillary electrophoresis usingN-(2-hydroxy-octyl)-L-4-hydroxyproline as a selector
  187. New set-up for capillary isoelectric focusing in uncoated capillaries