All Stories

  1. Reasons why risperidone and paliperidone should not be regarded as the same drug
  2. Synergy between selective serotonin reuptake inhibitors and α2-adrenergic receptor antagonists in the treatment of depression: Pharmacological rationale and clinical significance
  3. Association between CYP2D6 genotype and treatment effectiveness and safety in 99 hospitalized patients with major depressive disorder - a retrospective cohort study
  4. Pharmacotherapy: Advances in overcoming therapy based on trial-and-error
  5. Current level of evidence for improvement of antidepressant efficacy and tolerability by pharmacogenomic-guided treatment: A Systematic review and meta-analysis of randomized controlled clinical trials
  6. Social isolation during adolescence causes increased generalised anxiety-like behaviour in male rats and increased sociability in male and female rats
  7. What is the Current Clinical Impact of the CYP2CTG Haplotype?
  8. The humanised CYP2C19 transgenic mouse exhibits cerebellar atrophy and movement impairment reminiscent of ataxia
  9. Pharmacogenomics in treatment of depression and psychosis: an update
  10. Impact of NFIB and CYP1A variants on clozapine serum concentration—A retrospective naturalistic cohort study on 526 patients with known smoking habits
  11. Impact of the novel CYP2C:TG haplotype and CYP2B6 variants on sertraline exposure in a large patient population
  12. Association Between CYP2D6 Metabolizer Status and Vortioxetine Exposure and Treatment Switching
  13. CYP2C19 slow metabolizer phenotype is associated with lower antidepressant efficacy and tolerability
  14. Hepatocyte Thorns, A Novel Drug-Induced Stress Response in Human and Mouse Liver Spheroids
  15. The Polymorphic Nuclear Factor NFIB Regulates Hepatic CYP2D6 Expression and Influences Risperidone Metabolism in Psychiatric Patients
  16. Humanized CYP2C19 transgenic mouse as an animal model of cerebellar ataxia
  17. Patients' and psychiatrists' stance on the current state of pharmacological depression treatment in Serbia and prospects of introduction of personalized pharmacotherapy and its potential effects
  18. Synergy of oxytocin and citalopram in modulating Itgb3/Chl1 interplay: Relevance to sensitivity to SSRI therapy
  19. Evaluation of the CYP2D6 Haplotype Activity Scores Based on Metabolic Ratios of 4,700 Patients Treated With Three Different CYP2D6 Substrates
  20. CYP2D6 Reduced Function Variants and Genotype/Phenotype Translations of CYP2D6 Intermediate Metabolizers: Implications for Personalized Drug Dosing in Psychiatry
  21. A Novel CYP2C‐Haplotype Associated With Ultrarapid Metabolism of Escitalopram
  22. Association of CYP2C19 and CYP2D6 Poor and Intermediate Metabolizer Status With Antidepressant and Antipsychotic Exposure
  23. Rates of complete nonadherence among atypical antipsychotic drugs: A study using blood samples from 13,217 outpatients with psychotic disorders
  24. Long-Term Effects of Maternal Deprivation on the Volume of Dopaminergic Nuclei and Number of Dopaminergic Neurons in Substantia Nigra and Ventral Tegmental Area in Rats
  25. Can Gi1 biased 5-HT2A inverse agonists improve the treatment of psychosis?
  26. Impact of antipsychotic polypharmacy on nonadherence of oral antipsychotic drugs – A study based on blood sample analyses from 24,239 patients
  27. Pharmacogenomics of Antidepressant and Antipsychotic Treatment: How Far Have We Got and Where Are We Going?
  28. Impact of CYP2C19 genotype on sertraline exposure in 1200 Scandinavian patients
  29. Effect of CYP2D6 genotype on exposure and efficacy of risperidone and aripiprazole: a retrospective, cohort study
  30. Significantly lower CYP2D6 metabolism measured as the O/N ‐desmethylvenlafaxine metabolic ratio in carriers of CYP2D6*41 versus CYP2D6*9 or CYP2D6*10 : a st...
  31. Association between soft neurological signs and antioxidant enzyme activity in schizophrenic patients
  32. Functional characterization of CYP2D7 gene variants
  33. Impact of CYP2C19 Genotype on Escitalopram Exposure and Therapeutic Failure: A Retrospective Study Based on 2,087 Patients
  34. BMP/SMAD Pathway Promotes Neurogenesis of Midbrain Dopaminergic NeuronsIn Vivoand in Human Induced Pluripotent and Neural Stem Cells
  35. Dusp16 Deficiency Causes Congenital Obstructive Hydrocephalus and Brain Overgrowth by Expansion of the Neural Progenitor Pool
  36. Erratum: Elevated CYP2C19 expression is associated with depressive symptoms and hippocampal homeostasis impairment
  37. Elevated CYP2C19 expression is associated with depressive symptoms and hippocampal homeostasis impairment
  38. Molecular Mechanism and Clinical Relevance of Ketamine as Rapid-Acting Antidepressant
  39. Are adult neurogenesis and glucocorticoid signaling missing links between stress and depression?
  40. Otx2 Requires Lmx1b to Control the Development of Mesodiencephalic Dopaminergic Neurons
  41. Deciphering the spatio-temporal expression and stress regulation of Fam107B, the paralog of the resilience-promoting protein DRR1 in the mouse brain
  42. Polymorphic expression of CYP2C19 and CYP2D6 in the developing and adult human brain causing variability in cognition, risk for depression and suicide: the search for the endogenous substrates
  43. Abnormal Development of Monoaminergic Neurons Is Implicated in Mood Fluctuations and Bipolar Disorder