All Stories

  1. Association between CYP2D6 genotype and treatment effectiveness and safety in 99 hospitalized patients with major depressive disorder - a retrospective cohort study
  2. Pharmacotherapy: Advances in overcoming therapy based on trial-and-error
  3. Current level of evidence for improvement of antidepressant efficacy and tolerability by pharmacogenomic-guided treatment: A Systematic review and meta-analysis of randomized controlled clinical trials
  4. Social isolation during adolescence causes increased generalised anxiety-like behaviour in male rats and increased sociability in male and female rats
  5. What is the Current Clinical Impact of the CYP2CTG Haplotype?
  6. The humanised CYP2C19 transgenic mouse exhibits cerebellar atrophy and movement impairment reminiscent of ataxia
  7. Pharmacogenomics in treatment of depression and psychosis: an update
  8. Impact of NFIB and CYP1A variants on clozapine serum concentration—A retrospective naturalistic cohort study on 526 patients with known smoking habits
  9. Impact of the novel CYP2C:TG haplotype and CYP2B6 variants on sertraline exposure in a large patient population
  10. Association Between CYP2D6 Metabolizer Status and Vortioxetine Exposure and Treatment Switching
  11. CYP2C19 slow metabolizer phenotype is associated with lower antidepressant efficacy and tolerability
  12. Hepatocyte Thorns, A Novel Drug-Induced Stress Response in Human and Mouse Liver Spheroids
  13. The Polymorphic Nuclear Factor NFIB Regulates Hepatic CYP2D6 Expression and Influences Risperidone Metabolism in Psychiatric Patients
  14. Humanized CYP2C19 transgenic mouse as an animal model of cerebellar ataxia
  15. Patients' and psychiatrists' stance on the current state of pharmacological depression treatment in Serbia and prospects of introduction of personalized pharmacotherapy and its potential effects
  16. Synergy of oxytocin and citalopram in modulating Itgb3/Chl1 interplay: Relevance to sensitivity to SSRI therapy
  17. Evaluation of the CYP2D6 Haplotype Activity Scores Based on Metabolic Ratios of 4,700 Patients Treated With Three Different CYP2D6 Substrates
  18. CYP2D6 Reduced Function Variants and Genotype/Phenotype Translations of CYP2D6 Intermediate Metabolizers: Implications for Personalized Drug Dosing in Psychiatry
  19. A Novel CYP2C‐Haplotype Associated With Ultrarapid Metabolism of Escitalopram
  20. Association of CYP2C19 and CYP2D6 Poor and Intermediate Metabolizer Status With Antidepressant and Antipsychotic Exposure
  21. Rates of complete nonadherence among atypical antipsychotic drugs: A study using blood samples from 13,217 outpatients with psychotic disorders
  22. Long-Term Effects of Maternal Deprivation on the Volume of Dopaminergic Nuclei and Number of Dopaminergic Neurons in Substantia Nigra and Ventral Tegmental Area in Rats
  23. Can Gi1 biased 5-HT2A inverse agonists improve the treatment of psychosis?
  24. Impact of antipsychotic polypharmacy on nonadherence of oral antipsychotic drugs – A study based on blood sample analyses from 24,239 patients
  25. Pharmacogenomics of Antidepressant and Antipsychotic Treatment: How Far Have We Got and Where Are We Going?
  26. Impact of CYP2C19 genotype on sertraline exposure in 1200 Scandinavian patients
  27. Effect of CYP2D6 genotype on exposure and efficacy of risperidone and aripiprazole: a retrospective, cohort study
  28. Significantly lower CYP2D6 metabolism measured as the O/N ‐desmethylvenlafaxine metabolic ratio in carriers of CYP2D6*41 versus CYP2D6*9 or CYP2D6*10 : a st...
  29. Association between soft neurological signs and antioxidant enzyme activity in schizophrenic patients
  30. Functional characterization of CYP2D7 gene variants
  31. Impact of CYP2C19 Genotype on Escitalopram Exposure and Therapeutic Failure: A Retrospective Study Based on 2,087 Patients
  32. BMP/SMAD Pathway Promotes Neurogenesis of Midbrain Dopaminergic NeuronsIn Vivoand in Human Induced Pluripotent and Neural Stem Cells
  33. Dusp16 Deficiency Causes Congenital Obstructive Hydrocephalus and Brain Overgrowth by Expansion of the Neural Progenitor Pool
  34. Erratum: Elevated CYP2C19 expression is associated with depressive symptoms and hippocampal homeostasis impairment
  35. Elevated CYP2C19 expression is associated with depressive symptoms and hippocampal homeostasis impairment
  36. Molecular Mechanism and Clinical Relevance of Ketamine as Rapid-Acting Antidepressant
  37. Are adult neurogenesis and glucocorticoid signaling missing links between stress and depression?
  38. Otx2 Requires Lmx1b to Control the Development of Mesodiencephalic Dopaminergic Neurons
  39. Deciphering the spatio-temporal expression and stress regulation of Fam107B, the paralog of the resilience-promoting protein DRR1 in the mouse brain
  40. Polymorphic expression of CYP2C19 and CYP2D6 in the developing and adult human brain causing variability in cognition, risk for depression and suicide: the search for the endogenous substrates
  41. Abnormal Development of Monoaminergic Neurons Is Implicated in Mood Fluctuations and Bipolar Disorder