All Stories

  1. Human plasma proteomic profile of clonal hematopoiesis

    Article • Nature Communications, November 2025, Springer Science + Business Media

    Mr Abhishek Niroula

  2. JAK2-mutant clonal hematopoiesis is associated with venous thromboembolism

    Article • Blood, November 2024, American Society of Hematology

    Mr Abhishek Niroula

  3. Sequence variants influencing the regulation of serum IgG subclass levels

    Article • Nature Communications, September 2024, Springer Science + Business Media

    Mr Abhishek Niroula

  4. Clonal Hematopoiesis of Indeterminate Potential With Loss of Tet2 Enhances Risk for Atrial Fibrillation Through Nlrp3 Inflammasome Activation

    Article • Circulation, April 2024, Wolters Kluwer Health

    Mr Abhishek Niroula

  5. Risk factors for clonal hematopoiesis of indeterminate potential in people with HIV: a report from the REPRIEVE trial

    Article • Blood Advances, February 2024, American Society of Hematology

    Mr Abhishek Niroula

  6. Functional and molecular profiling of hematopoietic stem cells during regeneration

    Article • Experimental Hematology, November 2023, Elsevier

    Mr Abhishek Niroula

  7. Genetic modification of inflammation- and clonal hematopoiesis–associated cardiovascular risk

    Article • Journal of Clinical Investigation, September 2023, American Society for Clinical Investigation

    Mr Abhishek Niroula

  8. Long-term longitudinal analysis of 4,187 participants reveals new insights into determinants of incident clonal hematopoiesis

    Article • September 2023, openRxiv

    Mr Abhishek Niroula

  9. Clonal Hematopoiesis and Risk of Incident Lung Cancer

    Article • Journal of Clinical Oncology, March 2023, American Society of Clinical Oncology (ASCO)

    Mr Abhishek Niroula

  10. Author Correction: Functional dissection of inherited non-coding variation influencing multiple myeloma risk

    Article • Nature Communications, December 2022, Springer Science + Business Media

    Dr. Malte Thodberg, Mr Abhishek Niroula

  11. Genetic modification of inflammation and clonal hematopoiesis-associated cardiovascular risk

    Article • December 2022, openRxiv

    Mr Abhishek Niroula

  12. Germline genomic and phenomic landscape of clonal hematopoiesis in 323,112 individuals

    Article • July 2022, openRxiv

    Mr Abhishek Niroula

  13. Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential

    Article • Science Advances, April 2022, American Association for the Advancement of Science

    Mr Abhishek Niroula

  14. Clonal Hematopoiesis Is Associated With Higher Risk of Stroke

    Article • Stroke, March 2022, Wolters Kluwer Health

    Mr Abhishek Niroula

  15. Association of clonal hematopoiesis with chronic obstructive pulmonary disease

    Article • Blood, January 2022, American Society of Hematology

    Mr Abhishek Niroula

  16. Functional dissection of inherited non-coding variation influencing multiple myeloma risk

    Article • Nature Communications, January 2022, Springer Science + Business Media

    Dr. Malte Thodberg, Mr Abhishek Niroula

  17. Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis

    Article • Journal of Experimental Medicine, October 2021, Rockefeller University Press

    Mr Abhishek Niroula

  18. Distinction of lymphoid and myeloid clonal hematopoiesis

    Article • Nature Medicine, October 2021, Springer Science + Business Media

    Mr Abhishek Niroula

  19. Association of Diet Quality With Prevalence of Clonal Hematopoiesis and Adverse Cardiovascular Events

    Article • JAMA Cardiology, September 2021, American Medical Association (AMA)

    Mr Abhishek Niroula

  20. ZBTB33 Is Mutated in Clonal Hematopoiesis and Myelodysplastic Syndromes and Impacts RNA Splicing

    Article • Blood Cancer Discovery, July 2021, American Association for Cancer Research (AACR)

    Mr Abhishek Niroula

  21. Association of Clonal Hematopoiesis With Incident Heart Failure

    Article • Journal of the American College of Cardiology, July 2021, Elsevier

    Mr Abhishek Niroula

  22. Prognostic implications of troponin T variations in inherited cardiomyopathies using systems biology

    Article • npj Genomic Medicine, June 2021, Springer Science + Business Media

    Mr Abhishek Niroula

  23. Germline variants at SOHLH2 influence multiple myeloma risk

    Article • Blood Cancer Journal, April 2021, Springer Science + Business Media

    Mr Abhishek Niroula

  24. HLA Class I Genotypes with Predicted Strong Binding Affinity to Mutated NPM1 Are Associated with Lower Relapse Risk in Matched Related or Unrelated Transplant for NPM1 Mutated Acute Myeloid Leukemia

    Article • Transplantation and Cellular Therapy, March 2021, Elsevier

    Mr Abhishek Niroula

  25. Accelerating target deconvolution for therapeutic antibody candidates using highly parallelized genome editing

    Article • Nature Communications, February 2021, Springer Science + Business Media

    Mr Abhishek Niroula

  26. Premature Menopause, Clonal Hematopoiesis, and Coronary Artery Disease in Postmenopausal Women

    Article • Circulation, February 2021, Wolters Kluwer Health

    Mr Abhishek Niroula

  27. S100A6 is a critical regulator of hematopoietic stem cells

    Article • Leukemia, June 2020, Springer Science + Business Media

    Akos Vegvari, Mr Abhishek Niroula

  28. Identification of germline variants in adults with hemophagocytic lymphohistiocytosis

    Article • Blood Advances, March 2020, American Society of Hematology

    Mr Abhishek Niroula

  29. ProTstab – predictor for cellular protein stability

    Article • BMC Genomics, November 2019, Springer Science + Business Media

    Mr Abhishek Niroula

  30. MPRAscore: robust and non-parametric analysis of massively parallel reporter assays

    Article • Bioinformatics, July 2019, Oxford University Press (OUP)

    Mr Abhishek Niroula

  31. How good are pathogenicity predictors in detecting benign variants?

    Article • PLoS Computational Biology, February 2019, PLOS

    Mauno Vihinen, Mr Abhishek Niroula

  32. How good are pathogenicity predictors in detecting benign variants?

    Article • September 2018, Cold Spring Harbor Laboratory Press

    Mr Abhishek Niroula

  33. The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression

    Article • Nature Communications, April 2018, Springer Science + Business Media

    Mr Abhishek Niroula

  34. PON-tstab: Protein Variant Stability Predictor. Importance of Training Data Quality

    Article • International Journal of Molecular Sciences, March 2018, MDPI AG

    Mr Abhishek Niroula

  35. Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges

    Article • Human Mutation, July 2017, Wiley

    Gaia Andreoletti, Mr Abhishek Niroula

  36. Performance of in silico tools for the evaluation of p16INK4a (CDKN2A) variants in CAGI

    Article • Human Mutation, May 2017, Wiley

    Dr MARIA CHIARA SCAINI, Professor Yaoqi Zhou, Mr Abhishek Niroula

  37. Predicting Severity of Disease-Causing Variants

    Article • Human Mutation, January 2017, Wiley

    Mr Abhishek Niroula

  38. Variation Interpretation Predictors: Principles, Types, Performance, and Choice

    Article • Human Mutation, April 2016, Wiley

    Mr Abhishek Niroula

  39. PON-Sol: prediction of effects of amino acid substitutions on protein solubility

    Article • Bioinformatics, February 2016, Oxford University Press (OUP)

    Mr Abhishek Niroula

  40. PON-mt-tRNA: a multifactorial probability-based method for classification of mitochondrial tRNA variations

    Article • Nucleic Acids Research, February 2016, Oxford University Press (OUP)

    Mr Abhishek Niroula

  41. Classification of Amino Acid Substitutions in Mismatch Repair Proteins Using PON-MMR2

    Article • Human Mutation, September 2015, Wiley

    Mr Abhishek Niroula

  42. Harmful somatic amino acid substitutions affect key pathways in cancers

    Article • BMC Medical Genomics, August 2015, Springer Science + Business Media

    Mr Abhishek Niroula

  43. PON-P2 for predicting pathogenicity of non-synonymous variations

    Article • PLOS One, February 2015, PLOS

    Mr Abhishek Niroula