Antituberculosis nanodelivery system with controlled-release properties based on para-amino salicylate–zinc aluminum-layered double-hydroxide nanocomposites

Saifullah Bullo, Mohd Zobir Hussein, Samer Hussein-Al-Ali, Sharida Fakurazi, Palanisamy Arulselvan
  • Drug Design Development and Therapy, November 2013, Taylor & Francis
  • DOI: 10.2147/dddt.s50665

Nanodelivery system for anti-Tuberculosis drug para amino salicylic acid

What is it about?

We designed biocompatible nanodelivery systems for anti-Tuberculosis drug para amino salicylic acid by encapsulating it into Zn/Al layered double hydroxides.

Why is it important?

The designed Zn/Al-LDHS nanodelivery has higher efficacy than free drug, and highly biocompatible with human normal lung cells. The nanodlivery system relseases the anti-TB drug in a sustained manner in human body simulated PBS solution. The current research is an important step in making the chemotherapy of TB patient friendly.

Read Publication

The following have contributed to this page: SAIFULLAH BULLO, Dr Sharida Fakurazi, Professor MOHD ZOBIR HUSSEIN, and Dr PALANISAMY ARULSELVAN