Antituberculosis nanodelivery system with controlled-release properties based on para-amino salicylate–zinc aluminum-layered double-hydroxide nanocomposites

Saifullah Bullo, Mohd Zobir Hussein, Samer Hussein-Al-Ali, Sharida Fakurazi, Palanisamy Arulselvan
  • Drug Design Development and Therapy, November 2013, Taylor & Francis
  • DOI: 10.2147/dddt.s50665

Nanodelivery system for anti-Tuberculosis drug para amino salicylic acid

What is it about?

We designed biocompatible nanodelivery systems for anti-Tuberculosis drug para amino salicylic acid by encapsulating it into Zn/Al layered double hydroxides.

Why is it important?

The designed Zn/Al-LDHS nanodelivery has higher efficacy than free drug, and highly biocompatible with human normal lung cells. The nanodlivery system relseases the anti-TB drug in a sustained manner in human body simulated PBS solution. The current research is an important step in making the chemotherapy of TB patient friendly.

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http://dx.doi.org/10.2147/dddt.s50665

The following have contributed to this page: SAIFULLAH BULLO, Dr Sharida Fakurazi, Professor MOHD ZOBIR HUSSEIN, and Dr PALANISAMY ARULSELVAN