What is it about?
This study investigated the carriage of AmpC gene among multidrug-resistant Salmonella spp. from Lagos, Nigeria. The study identified emergence of AmpC b-lactamase–producing Salmonella isolates in our environmentwas recorded for the first time, raising concern on increased antibiotic resistance among strains of Salmonella serovars in Lagos.
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Why is it important?
This study revealed the occurrence of plasmid-mediated AmpC β-lactamases producing MDR Salmonella isolates in our environment for the first time. It also showed the coexistence of ESBL and AmpC β-lactamases (fox gene) in some strains of Salmonella isolates. A need to screen the ESBL potential of MDR Salmonella isolates for plasmid-mediated AmpC β-lactamases, along with performing antibiogram is advocated before making therapeutic decisions in patient management in our hospitals. This is essential to prevent treatment failure and stem mortality.
Read the Original
This page is a summary of: Occurrence of extended-spectrum and AmpC β-lactamases in multiple drug resistant Salmonella isolates from clinical samples in Lagos, Nigeria, Infection and Drug Resistance, January 2017, Dove Medical Press, DOI: 10.2147/idr.s123646.
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