What is it about?
Porcine reproductive and respiratory syndrome virus (PRRSV2) causes important losses in pigs. We have shown that in the United States, smaller viral genetic variability amongst samples submitted for routine diagnosis was found in years in which a group of closely related viruses (i.e. lineage) were predominant. We also found that about one fourth of all submitted samples were similar to vaccine-like viruses and that after the introduction of commercial live modified virus vaccines in the U.S. market, diversity within lineage decreased.
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Why is it important?
Understanding PRRSV2 expected genetic diversity is important since producers and veterinarians have been investing in diagnostics and sequencing as a way to further understand the epidemiology of PRRSV at both the farm and production system level in the past decades. This study also provides insights on the effect of repeated introductions of vaccine-like viruses through use of modified-live vaccines in within-lineage viral diversity.
Perspectives
This study is an example of how private data sharing from routine monitoring can provide valuable information to the scientific community as well as industry stakeholders, particularly when reporting such disease is not mandatory and no representative publicly available data repository exists.
Mariana Kikuti
University of Minnesota Twin Cities
Read the Original
This page is a summary of: Porcine reproductive and respiratory syndrome virus 2 (PRRSV-2) genetic diversity and occurrence of wild type and vaccine-like strains in the United States swine industry, PLoS ONE, November 2021, PLOS,
DOI: 10.1371/journal.pone.0259531.
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