What is it about?
Prior work proposed that memory reinstatement of items together with the context in which they were learned is associated with hippocampal activity. Can hippocampal activity distinguish between false and correct memories? Using direct hippocampal recordings in humans, we characterize a spectral fingerprint distinguishing correct from false memories in the moments preceding memory retrieval. Oscillations in the 6-18 Hz range further reflected the degree of similarity between the retrieved item and the correct context. Desynchronization of this low-frequency activity indicated a greater similarity between the context in which the false and correct items were learned.
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Why is it important?
The findings shed light on the mechanisms underlying the brain's ability to associate the information we acquire with its surrounding context, thereby facilitating our capacity to relive past experiences.
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This page is a summary of: Hippocampal activity predicts contextual misattribution of false memories, Proceedings of the National Academy of Sciences, September 2023, Proceedings of the National Academy of Sciences,
DOI: 10.1073/pnas.2305292120.
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