What is it about?

The gut microbiome is a community of bacteria living in your stomach and colon. We show that after a brain injury, these bacteria become disrupted. Moreover, this disruption is linked to long-term psychiatric impairments such as impulsivity and risky decision-making.

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Why is it important?

Knowledge on the gut microbiome is rapidly expanding. However, it's potential role in the pathology of brain injury is still poorly defined. The current work expands upon this to try and understand whether this pathology reflects dysfunction or is actually causal to it.

Perspectives

This work sets the stage for other important experiments to truly isolate causality of the gut microbiome to psychiatric-related symptoms.

Cole Vonder Haar
Ohio State University

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This page is a summary of: Acute gut microbiome changes after traumatic brain injury are associated with chronic deficits in decision-making and impulsivity in male rats., Behavioral Neuroscience, July 2022, American Psychological Association (APA), DOI: 10.1037/bne0000532.
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