What is it about?

Three methods are currently used interchangeably to simulate hemolysis in interference studies; the Osmotic shock method, the Freeze method and the Shear method. We found that different test results can occur due to the method used in the preparation of samples with hemolysis.

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Why is it important?

Different test results can occur due to the method used in the preparation of samples with hemolysis for hemolysis interference studies.

Perspectives

The strengths in this study are that three methods often used in the preparation of hemolyzed samples were, to our knowledge, compared for the first time, and both wet-reagent and dry-slide-reagent instruments were used.

Gro Gidske
Norwegian Quality Improvement of laboratory examinations (Noklus)

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This page is a summary of: Hemolysis interference studies: freeze method should be used in the preparation of hemolyzed samples, Clinical Chemistry and Laboratory Medicine (CCLM), April 2018, De Gruyter, DOI: 10.1515/cclm-2018-0193.
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