Current affiliation: University of AberdeenSubject: Life SciencesPrimary location: United Kingdom
Published in:Open BiologyPublication date:2013-09-11
Published in:SciencePublication date:2012-06-21
This was one of the first studies to establish a complete understanding of the crossover/non-crossover decision during meiosis. We show that the FA...
Published in:Methods in Molecular BiologyPublication date:2009-01-01
Published in:Current GeneticsPublication date:2012-02-24
Published in:ChromosomaPublication date:2006-03-31
Localization of the recombination factors Rec7 and Rad51 depends on the presence of meiotic chromosome axes; this suggests that chromosome axes for...
Published in:Eukaryotic CellPublication date:2003-10-01
Published in:GeneticsPublication date:2008-04-01
Published in:Molecular and Cellular BiologyPublication date:2010-02-01
We reveal the role of two factors associated with meiotic chromosome axes, Hop1 and Mek1, in choosing the homologous chromosome over the sister chr...
Published in:Cell CyclePublication date:2012-09-15
A novel role for FANCM orthologs in meiotic recombination
Published in:PLoS ONEPublication date:2013-08-06
Published in:Molecular CellPublication date:2008-10-01
The fission yeast FANCM-ortholog Fml1 has two roles in homologous recombination – it promotes gene conversion at stalled replication forks and limi...
Published in:Biochemical Society TransactionsPublication date:2006-08-01
Published in:Nucleic Acids ResearchPublication date:2009-12-29
Various structure-selective endonucleases, such as Mus81-Eme1/Mms4, Yen1/GEN1, Slx1-Slx4, and/or XPF-ERCC1 process recombination intermediates into...
Published in:Molecular and Cellular BiologyPublication date:2009-06-22
The F-box DNA helicase (Fbh1) functions in direct opposition to Rad22 (=Rad52) to curb Rad51 loading onto DNA. This plays a key role in preventing ...
Published in:Nucleic Acids ResearchPublication date:2010-12-11
The DNA helicase Fbh1 serves a vital meiotic role in promoting normal chromosome segregation. In the absence of Fbh1, chromosomes remain entangled ...
Published in:Nucleic Acids ResearchPublication date:2011-05-16
Published in:Genes & DevelopmentPublication date:2012-03-15
The Pif1 family DNA helicase Pfh1 plays a dual role in promoting replication fork termination. First, it facilitates replication past DNA–protein b...
Published in:Molecular Biology of the CellPublication date:2006-01-18
Published in:GeneticsPublication date:2005-02-16
Published in:Journal of Cell SciencePublication date:2004-07-01
Due to the absence of a fully-fledged synaptonemal complex it had previously been hypothesized that fission yeast meiosis is evolutionary primitive...
Published in:Journal of Cell SciencePublication date:2002-10-01
Published in:PROTOPLASMAPublication date:2000-09-01
Published in:Nucleic Acids ResearchPublication date:2014-11-20
The meiotic strand exchange reaction driven by Rad51 and Dmc1 is supported by a group of ancillary factors, called mediators. These promote Mus81-d...
Published in:YeastPublication date:2015-09-17
New single-step marker swap cassettes for fission yeast
Construction of multiply mutated strains for genetic interaction analysis and of strains carrying different epitope tags at multiple open reading f...
Published in:Seminars in Cell and Developmental BiologyPublication date:2016-02-01
The protist Tetrahymena thermophila is an interesting model organism with some unique features; it also shows the largest phylogenetic distance to ...
Published in:Scientific ReportsPublication date:2016-03-09
DNA resection is the first critical step to start DNA double-strand repair via homologous recombination. Here we investigate the importance of exon...
Published in:Scientific ReportsPublication date:2016-04-14
During sexual reproduction the equivalent chromosomes originally inherited from mother and father have to find each other and pair up in order to b...
Published in:YeastPublication date:2016-01-01
DNA helicases and recombination
This review summarizes and explicates the the various roles of DNA helicases in meiotic recombination. It discusses the recent progresses being mad...
Published in:BIO-PROTOCOLPublication date:2016-01-01
Published in:Current GeneticsPublication date:2018-03-17
Published in:Not availablePublication date:2017-09-18