All Stories

  1. N-6-Methyladenosine in Vasoactive microRNAs during Hypoxia; A Novel Role for METTL4

    Article • International Journal of Molecular Sciences, January 2022, MDPI AG

    Professor Paul HA Quax

  2. Response to Letter to the Editor From Behar-Cohen et al.: The Cortisol Response of Male and Female Choroidal Endothelial Cells: Implications for Central Serous Chorioretinopathy

    Article • The Journal of Clinical Endocrinology & Metabolism, December 2021, Endocrine Society

    Professor Paul HA Quax

  3. Arteriogenesis and Therapeutic Angiogenesis—An Update

    Article • International Journal of Molecular Sciences, December 2021, MDPI AG

    Professor Paul HA Quax

  4. Inhibition of microRNA-494-3p activates Wnt signaling and reduces proinflammatory macrophage polarization in atherosclerosis

    Article • Molecular Therapy — Nucleic Acids, December 2021, Elsevier

    Professor Paul HA Quax

  5. Cold-Inducible RNA-Binding Protein but Not Its Antisense lncRNA Is a Direct Negative Regulator of Angiogenesis In Vitro and In Vivo via Regulation of the 14q32 angiomiRs—microRNA-329-3p and microRNA-495-3p

    Article • International Journal of Molecular Sciences, November 2021, MDPI AG

    Professor Paul HA Quax

  6. C/D box snoRNA SNORD113-6/AF357425 plays a dual role in integrin signalling and arterial fibroblast function via pre-mRNA processing and 2′O-ribose methylation

    Article • Human Molecular Genetics, October 2021, Oxford University Press (OUP)

    Professor Paul HA Quax

  7. Perfusion Patterns in Patients with Chronic Limb-Threatening Ischemia versus Control Patients Using Near-Infrared Fluorescence Imaging with Indocyanine Green

    Article • Biomedicines, October 2021, MDPI AG

    Professor Paul HA Quax

  8. Derivation and characterisation of endothelial cells from patients with chronic thromboembolic pulmonary hypertension

    Article • Scientific Reports, September 2021, Springer Science + Business Media

    Professor Paul HA Quax

  9. The Cortisol Response of Male and Female Choroidal Endothelial Cells: Implications for Central Serous Chorioretinopathy

    Article • The Journal of Clinical Endocrinology & Metabolism, September 2021, Endocrine Society

    Professor Paul HA Quax

  10. PFKFB3 gene deletion in endothelial cells inhibits intraplaque angiogenesis and lesion formation in a murine model of venous bypass grafting

    Article • Angiogenesis, August 2021, Springer Science + Business Media

    Professor Paul HA Quax

  11. In Vivo Matrigel Plug Assay as a Potent Method to Investigate Specific Individual Contribution of Angiogenesis to Blood Flow Recovery in Mice

    Article • International Journal of Molecular Sciences, August 2021, MDPI AG

    Professor Paul HA Quax

  12. Exploring the choroidal vascular labyrinth and its molecular and structural roles in health and disease

    Article • Progress in Retinal and Eye Research, July 2021, Elsevier

    Professor Paul HA Quax

  13. Phosphorylcholine antibodies restrict infarct size and left ventricular remodelling by attenuating the unreperfused post‐ischaemic inflammatory response

    Article • Journal of Cellular and Molecular Medicine, June 2021, Wiley

    Professor Paul HA Quax

  14. Endoglin/CD105-Based Imaging of Cancer and Cardiovascular Diseases: A Systematic Review

    Article • International Journal of Molecular Sciences, April 2021, MDPI AG

    Professor Paul HA Quax

  15. Post-ischemic Myocardial Inflammatory Response: A Complex and Dynamic Process Susceptible to Immunomodulatory Therapies

    Article • Frontiers in Cardiovascular Medicine, April 2021, Frontiers

    Professor Paul HA Quax

  16. The Inflammatory Profile of CTEPH-Derived Endothelial Cells Is a Possible Driver of Disease Progression

    Article • Cells, March 2021, MDPI AG

    Professor Paul HA Quax

  17. Endothelial Barrier Function and Leukocyte Transmigration in Atherosclerosis

    Article • Biomedicines, March 2021, MDPI AG

    Professor Paul HA Quax

  18. BMP Receptor Inhibition Enhances Tissue Repair in Endoglin Heterozygous Mice

    Article • International Journal of Molecular Sciences, February 2021, MDPI AG

    Professor Paul HA Quax

  19. Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization

    Article • Angiogenesis, February 2021, Springer Science + Business Media

    Professor Paul HA Quax

  20. Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases

    Article • Journal of Internal Medicine, February 2021, Wiley

    Professor Paul HA Quax

  21. P300/CBP Associated Factor (PCAF) Deficiency Enhances Diet-Induced Atherosclerosis in ApoE3*Leiden Mice via Systemic Inhibition of Regulatory T Cells

    Article • Frontiers in Cardiovascular Medicine, January 2021, Frontiers

    Professor Paul HA Quax

  22. Endothelial Dysfunction in Pulmonary Hypertension: Cause or Consequence?

    Article • Biomedicines, January 2021, MDPI AG

    Professor Paul HA Quax

  23. Circulating tRNA Fragments as a Novel Biomarker Class to Distinguish Acute Stroke Subtypes

    Article • International Journal of Molecular Sciences, December 2020, MDPI AG

    Professor Paul HA Quax

  24. Assessment of Microvessel Permeability in Murine Atherosclerotic Vein Grafts Using Two-Photon Intravital Microscopy

    Article • International Journal of Molecular Sciences, December 2020, MDPI AG

    Professor Paul HA Quax

  25. Phosphorylcholine Antibodies Preserve Cardiac Function and Reduce Infarct Size by Attenuating the Post-Ischemic Inflammatory Response

    Article • JACC Basic to Translational Science, December 2020, Elsevier

    Professor Paul HA Quax

  26. Periprocedural Hydrogen Sulfide Therapy Improves Vascular Remodeling and Attenuates Vein Graft Disease

    Article • Journal of the American Heart Association, November 2020, Wolters Kluwer Health

    Professor Paul HA Quax

  27. Decreased Glycolysis as Metabolic Fingerprint of Endothelial Cells in Chronic Thromboembolic Pulmonary Hypertension

    Article • American Journal of Respiratory Cell and Molecular Biology, November 2020, American Thoracic Society

    Professor Paul HA Quax

  28. Effects on cardiac function, remodeling and inflammation following myocardial ischemia–reperfusion injury or unreperfused myocardial infarction in hypercholesterolemic APOE*3-Leiden mice

    Article • Scientific Reports, October 2020, Springer Science + Business Media

    Professor Paul HA Quax

  29. bFGF blockade reduces intraplaque angiogenesis and macrophage infiltration in atherosclerotic vein graft lesions in ApoE3*Leiden mice

    Article • Scientific Reports, September 2020, Springer Science + Business Media

    Professor Paul HA Quax

  30. Adenosine-to-Inosine Editing of Vasoactive MicroRNAs Alters Their Targetome and Function in Ischemia

    Article • Molecular Therapy — Nucleic Acids, September 2020, Elsevier

    Professor Paul HA Quax

  31. Molecular imaging of the urokinase plasminogen activator receptor: opportunities beyond cancer

    Article • EJNMMI Research, July 2020, Springer Science + Business Media

    Dr. CFM Sier, Professor Paul HA Quax

  32. Three-Dimensional Imaging of Intraplaque Neovascularization in a Mouse Model of Advanced Atherosclerosis

    Article • Journal of Vascular Research, July 2020, Karger Publishers

    Professor Paul HA Quax

  33. Bis(maltolato)oxovanadium(IV) Induces Angiogenesis via Phosphorylation of VEGFR2

    Article • International Journal of Molecular Sciences, June 2020, MDPI AG

    Professor Paul HA Quax

  34. The Role of Immunomodulation in Vein Graft Remodeling and Failure

    Article • Journal of Cardiovascular Translational Research, June 2020, Springer Science + Business Media

    Professor Paul HA Quax

  35. Arteriogenesis and Therapeutic Angiogenesis in Its Multiple Aspects

    Article • Cells, June 2020, MDPI AG

    Professor Paul HA Quax

  36. From Increased Fluid Shear Stress to Natural Bypass Growth

    Article • International Journal of Molecular Sciences, May 2020, MDPI AG

    Professor Paul HA Quax

  37. Myostatin Inhibits Vascular Smooth Muscle Cell Proliferation and Local 14q32 microRNA Expression, But Not Systemic Inflammation or Restenosis

    Article • International Journal of Molecular Sciences, May 2020, MDPI AG

    Professor Paul HA Quax

  38. Therapeutic Antibody Against Phosphorylcholine Preserves Coronary Function and Attenuates Vascular 18F-FDG Uptake in Atherosclerotic Mice

    Article • JACC Basic to Translational Science, April 2020, Elsevier

    Professor Paul HA Quax

  39. Loss of Endothelial Glycocalyx Hyaluronan Impairs Endothelial Stability and Adaptive Vascular Remodeling after Arterial Ischemia

    Article • Cells, March 2020, MDPI AG

    Professor Paul HA Quax

  40. Local Mast Cell Activation Promotes Neovascularization

    Article • Cells, March 2020, MDPI AG

    Professor Paul HA Quax

  41. Prolonged Hyperoxygenation Treatment Improves Vein Graft Patency and Decreases Macrophage Content in Atherosclerotic Lesions in ApoE3*Leiden Mice

    Article • Cells, February 2020, MDPI AG

    Professor Paul HA Quax

  42. MicroRNA-411 and Its 5′-IsomiR Have Distinct Targets and Functions and Are Differentially Regulated in the Vasculature under Ischemia

    Article • Molecular Therapy, January 2020, Elsevier

    Professor Paul HA Quax

  43. An Emerging Role for isomiRs and the microRNA Epitranscriptome in Neovascularization

    Article • Cells, December 2019, MDPI AG

    Professor Paul HA Quax

  44. Antisense Oligonucleotide Inhibition of MicroRNA-494 Halts Atherosclerotic Plaque Progression and Promotes Plaque Stabilization

    Article • Molecular Therapy — Nucleic Acids, December 2019, Elsevier

    Professor Paul HA Quax

  45. Akkermansia muciniphila Exerts Lipid‐Lowering and Immunomodulatory Effects without Affecting Neointima Formation in Hyperlipidemic APOE*3‐Leiden.CETP Mice

    Article • Molecular Nutrition & Food Research, August 2019, Wiley

    Professor Paul HA Quax

  46. miRMap: Profiling 14q32 microRNA Expression and DNA Methylation Throughout the Human Vasculature

    Article • Frontiers in Cardiovascular Medicine, August 2019, Frontiers

    Professor Paul HA Quax

  47. Variations in Surgical Procedures for Inducing Hind Limb Ischemia in Mice and the Impact of These Variations on Neovascularization Assessment

    Article • International Journal of Molecular Sciences, July 2019, MDPI AG

    Professor Paul HA Quax

  48. Corrigendum to “Dexamethasone-eluting stents for the prevention of in-stent restenosis: Evidence for a differential effect in insulin-dependent and non-insulin-dependent diabetic patients” [Int. J. Cardiol. 124 (2008) 166–171]

    Article • International Journal of Cardiology, July 2019, Elsevier

    Professor Paul HA Quax

  49. Hypercholesterolemia affects cardiac function, infarct size and inflammation in APOE*3-Leiden mice following myocardial ischemia-reperfusion injury

    Article • PLoS ONE, June 2019, PLOS

    Professor Paul HA Quax

  50. CD8+ T Cells Protect During Vein Graft Disease Development

    Article • Frontiers in Cardiovascular Medicine, June 2019, Frontiers

    Professor Paul HA Quax

  51. Flow Cytometry-Based Characterization of Mast Cells in Human Atherosclerosis

    Article • Cells, April 2019, MDPI AG

    Professor Paul HA Quax

  52. IRF3 and IRF7 mediate neovascularization via inflammatory cytokines

    Article • Journal of Cellular and Molecular Medicine, April 2019, Wiley

    Professor Paul HA Quax

  53. Short-Term Preoperative Protein Restriction Attenuates Vein Graft Disease via Induction of Cystathionine ϒ-Lyase

    Article • Cardiovascular Research, March 2019, Oxford University Press (OUP)

    Professor Paul HA Quax

  54. Posttranscriptional Regulation of 14q32 MicroRNAs by the CIRBP and HADHB during Vascular Regeneration after Ischemia

    Article • Molecular Therapy — Nucleic Acids, March 2019, Elsevier

    Professor Paul HA Quax

  55. T cell co-stimulation and co-inhibition in cardiovascular disease: a double-edged sword

    Article • Nature Reviews Cardiology, February 2019, Springer Science + Business Media

    Professor Paul HA Quax

  56. Metabolic Alterations in Cardiopulmonary Vascular Dysfunction

    Article • Frontiers in Molecular Biosciences, January 2019, Frontiers

    Professor Paul HA Quax

  57. Genetic associations and regulation of expression indicate an independent role for 14q32 snoRNAs in Human Cardiovascular Disease

    Article • Cardiovascular Research, December 2018, Oxford University Press (OUP)

    Professor Paul HA Quax, Kjell E J Håkansson

  58. The Effect of Corticosteroids on Human Choroidal Endothelial Cells: A Model to Study Central Serous Chorioretinopathy

    Article • Investigative Ophthalmology & Visual Science, November 2018, Association for Research in Vision and Ophthalmology (ARVO)

    Professor Paul HA Quax

  59. Blockade of vascular endothelial growth factor receptor 2 inhibits intraplaque haemorrhage by normalization of plaque neovessels

    Article • Journal of Internal Medicine, September 2018, Wiley

    Professor Paul HA Quax

  60. Circulating Small Non-coding RNAs as Biomarkers for Recovery After Exhaustive or Repetitive Exercise

    Article • Frontiers in Physiology, August 2018, Frontiers

    Professor Paul HA Quax, Kjell E J Håkansson

  61. Lipocalin-2 contributes to experimental atherosclerosis in a stage-dependent manner

    Article • Atherosclerosis, August 2018, Elsevier

    Professor Paul HA Quax

  62. Systemic Upregulation of IL-10 (Interleukin-10) Using a Nonimmunogenic Vector Reduces Growth and Rate of Dissecting Abdominal Aortic Aneurysm

    Article • Arteriosclerosis Thrombosis and Vascular Biology, August 2018, Wolters Kluwer Health

    Professor Paul HA Quax

  63. The protective role of Toll-like receptor 3 and type-I interferons in the pathophysiology of vein graft disease

    Article • Journal of Molecular and Cellular Cardiology, August 2018, Elsevier

    Professor Paul HA Quax

  64. Relaxin receptor deficiency promotes vascular inflammation and impairs outward remodeling in arteriovenous fistulas

    Article • The FASEB Journal, June 2018, Federation of American Societies For Experimental Biology (FASEB)

    Taisiya Bezhaeva, Professor Paul HA Quax, Dr. Eric P van der Veer, Prof Anton Jan van Zonneveld

  65. The role of CD27-CD70-mediated T cell co-stimulation in vasculogenesis, arteriogenesis and angiogenesis

    Article • International Journal of Cardiology, June 2018, Elsevier

    Professor Paul HA Quax

  66. Consensus guidelines for the use and interpretation of angiogenesis assays

    Article • Angiogenesis, May 2018, Springer Science + Business Media

    Professor Paul HA Quax

  67. Annexin A5 reduces infarct size and improves cardiac function after myocardial ischemia-reperfusion injury by suppression of the cardiac inflammatory response

    Article • Scientific Reports, April 2018, Springer Science + Business Media

    Professor Paul HA Quax

  68. Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo

    Article • Cell Stem Cell, April 2018, Elsevier

    Professor Paul HA Quax

  69. The Prebiotic Inulin Aggravates Accelerated Atherosclerosis in Hypercholesterolemic APOE*3-Leiden Mice

    Article • Nutrients, February 2018, MDPI AG

    Professor Paul HA Quax

  70. Adenosine-to-Inosine Editing of MicroRNA-487b Alters Target Gene Selection After Ischemia and Promotes Neovascularization

    Article • Circulation Research, February 2018, Wolters Kluwer Health

    Professor Paul HA Quax

  71. Inflammation in Vein Graft Disease

    Article • Frontiers in Cardiovascular Medicine, January 2018, Frontiers

    Professor Paul HA Quax

  72. Plaque angiogenesis and intraplaque hemorrhage in atherosclerosis

    Article • European Journal of Pharmacology, December 2017, Elsevier

    Professor Paul HA Quax

  73. The epigenetic factor PCAF regulates vascular inflammation and is essential for intimal hyperplasia development

    Article • PLoS ONE, October 2017, PLOS

    Professor Paul HA Quax

  74. A protective role of IRF3 and IRF7 signalling downstream TLRs in the development of vein graft disease via type I interferons

    Article • Journal of Internal Medicine, September 2017, Wiley

    Professor Paul HA Quax

  75. Deficiency of TLR4 homologue RP105 aggravates outward remodeling in a murine model of arteriovenous fistula failure

    Article • Scientific Reports, August 2017, Springer Science + Business Media

    Professor Paul HA Quax

  76. Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics

    Article • Cell Reports, August 2017, Elsevier

    Professor Paul HA Quax

  77. PX-18 Protects Human Saphenous Vein Endothelial Cells under Arterial Blood Pressure

    Article • Annals of Vascular Surgery, July 2017, Elsevier

    Professor Paul HA Quax

  78. Inhibition of 14q32 microRNA miR-495 reduces lesion formation, intimal hyperplasia and plasma cholesterol levels in experimental restenosis

    Article • Atherosclerosis, June 2017, Elsevier

    Professor Paul HA Quax

  79. Inhibition of Mef2a Enhances Neovascularization via Post-transcriptional Regulation of 14q32 MicroRNAs miR-329 and miR-494

    Article • Molecular Therapy — Nucleic Acids, June 2017, Elsevier

    Professor Paul HA Quax

  80. Arterial Blood Pressure Induces Transient C4b-Binding Protein in Human Saphenous Vein Grafts

    Article • Annals of Vascular Surgery, May 2017, Elsevier

    Professor Paul HA Quax

  81. High-throughput identification of small molecules that affect human embryonic vascular development

    Article • Proceedings of the National Academy of Sciences, March 2017, Proceedings of the National Academy of Sciences

    Professor Paul HA Quax

  82. CCR7‐CCL19/CCL21 Axis is Essential for Effective Arteriogenesis in a Murine Model of Hindlimb Ischemia

    Article • Journal of the American Heart Association, March 2017, Wolters Kluwer Health

    Professor Paul HA Quax

  83. von Willebrand factor deficiency leads to impaired blood flow recovery after ischaemia in mice

    Article • Thrombosis and Haemostasis, January 2017, Thieme Publishing Group

    Professor Paul HA Quax

  84. Plaque angiogenesis and its relation to inflammation and atherosclerotic plaque destabilization

    Article • Current Opinion in Lipidology, October 2016, Wolters Kluwer Health

    Professor Paul HA Quax

  85. Liposomal prednisolone inhibits vascular inflammation and enhances venous outward remodeling in a murine arteriovenous fistula model

    Article • Scientific Reports, July 2016, Springer Science + Business Media

    Professor Paul HA Quax

  86. Vein graft failure: from pathophysiology to clinical outcomes

    Article • Nature Reviews Cardiology, May 2016, Springer Science + Business Media

    Professor Paul HA Quax

  87. Deficiency of the TLR4 analogue RP105 aggravates vein graft disease by inducing a pro-inflammatory response

    Article • Scientific Reports, April 2016, Springer Science + Business Media

    Professor Paul HA Quax

  88. The multifactorial nature of microRNAs in vascular remodelling

    Article • Cardiovascular Research, February 2016, European Society of Cardiology

    Professor Paul HA Quax

  89. Heat-killedStaphylococcus aureusreduces atherosclerosis by inducing anti-inflammatory macrophages

    Article • Journal of Internal Medicine, February 2016, Wiley

    Professor Paul HA Quax

  90. A Novel Murine Model of Arteriovenous Fistula Failure: The Surgical Procedure in Detail

    Article • Journal of Visualized Experiments, February 2016, MyJove Corporation

    Professor Paul HA Quax

  91. Innate Immunity and Vein Graft Disease

    Article • January 2016, Springer Science + Business Media

    Professor Paul HA Quax

  92. CXCL1 microspheres: a novel tool to stimulate arteriogenesis

    Article • Drug Delivery, December 2015, Taylor & Francis

    Professor Paul HA Quax

  93. Letter Regarding Article, “MicroRNA-155 Exerts Cell-Specific Antiangiogenic but Proarteriogenic Effects During Adaptive Neovascularization”

    Article • Circulation, December 2015, Wolters Kluwer Health

    Professor Paul HA Quax

  94. Inhibition of MicroRNA-494 Reduces Carotid Artery Atherosclerotic Lesion Development and Increases Plaque Stability

    Article • Annals of Surgery, November 2015, Wolters Kluwer Health

    Professor Paul HA Quax

  95. Circulating MicroRNAs Characterizing Patients with Insufficient Coronary Collateral Artery Function

    Article • PLoS ONE, September 2015, PLOS

    Professor Paul HA Quax

  96. Fibrinogen reduction and coagulation in cardiac surgery

    Article • Blood Coagulation & Fibrinolysis, September 2015, Wolters Kluwer Health

    Professor Paul HA Quax

  97. Mast cells mediate neutrophil recruitment during atherosclerotic plaque progression

    Article • Atherosclerosis, August 2015, Elsevier

    Professor Paul HA Quax

  98. Research ethics needs fine tuning, not rigidity: how to promote evidence in neglected patient populations by rethinking informed consent: Figure 1

    Article • European Heart Journal, July 2015, European Society of Cardiology

    Professor Paul HA Quax

  99. Galectin-2 Induces a Proinflammatory, Anti-Arteriogenic Phenotype in Monocytes and Macrophages

    Article • PLoS ONE, April 2015, PLOS

    Professor Paul HA Quax

  100. Elastin is a Key Regulator of Outward Remodeling in Arteriovenous Fistulas

    Article • European Journal of Vascular and Endovascular Surgery, April 2015, Elsevier

    Professor Paul HA Quax

  101. RP105 deficiency attenuates early atherosclerosis via decreased monocyte influx in a CCR2 dependent manner

    Article • Atherosclerosis, January 2015, Elsevier

    Professor Paul HA Quax

  102. The role of mast cells in atherosclerosis

    Article • Hämostaseologie, January 2015, Thieme Publishing Group

    Professor Paul HA Quax

  103. Neovascularization Capacity of Mesenchymal Stromal Cells From Critical Limb Ischemia Patients Is Equivalent to Healthy Controls

    Article • Molecular Therapy, November 2014, Elsevier

    Professor Paul HA Quax

  104. RP105 deficiency aggravates cardiac dysfunction after myocardial infarction in mice

    Article • International Journal of Cardiology, October 2014, Elsevier

    Professor Paul HA Quax

  105. Inhibition of 14q32 MicroRNAs miR-329, miR-487b, miR-494, and miR-495 Increases Neovascularization and Blood Flow Recovery After Ischemia

    Article • Circulation Research, September 2014, Wolters Kluwer Health

    Professor Paul HA Quax

  106. Complement factor C5a induces atherosclerotic plaque disruptions

    Article • Journal of Cellular and Molecular Medicine, August 2014, Wiley

    Professor Paul HA Quax

  107. TLR4 Accessory Molecule RP105 (CD180) Regulates Monocyte-Driven Arteriogenesis in a Murine Hind Limb Ischemia Model

    Article • PLoS ONE, June 2014, PLOS

    Professor Paul HA Quax

  108. The CD200-CD200 Receptor Inhibitory Axis Controls Arteriogenesis and Local T Lymphocyte Influx

    Article • PLoS ONE, June 2014, PLOS

    Professor Paul HA Quax

  109. PS210. Inhibition of VEGFR2 Reduces Angiogenic Microvessel Leakiness in Murine Vein Graft Atherosclerotic Lesions and Increased Plaque Stability

    Article • Journal of Vascular Surgery, June 2014, Elsevier

    Professor Paul HA Quax

  110. Absence of Chemokine (C-X-C Motif) Ligand 10 Diminishes Perfusion Recovery After Local Arterial Occlusion in Mice

    Article • Arteriosclerosis Thrombosis and Vascular Biology, March 2014, Wolters Kluwer Health

    Professor Paul HA Quax

  111. Circulating Immunoglobulins Are Not Associated with Intraplaque Mast Cell Number and Other Vulnerable Plaque Characteristics in Patients with Carotid Artery Stenosis

    Article • PLoS ONE, February 2014, PLOS

    Professor Paul HA Quax

  112. Leukotriene B4 Levels in Human Atherosclerotic Plaques and Abdominal Aortic Aneurysms

    Article • PLoS ONE, January 2014, PLOS

    Professor Paul HA Quax

  113. Vascular remodeling and intimal hyperplasia in a novel murine model of arteriovenous fistula failure

    Article • Journal of Vascular Surgery, January 2014, Elsevier

    Professor Paul HA Quax

  114. Toll-like Receptor 4 Inhibitor TAK-242 Treatment Does Not Influence Perfusion Recovery in Tissue Ischemia

    Article • Journal of Cardiovascular Pharmacology, January 2014, Wolters Kluwer Health

    Professor Paul HA Quax

  115. The Multifaceted Functions of CXCL10 in Cardiovascular Disease

    Article • BioMed Research International, January 2014, Hindawi Publishing Corporation

    Professor Paul HA Quax

  116. Short Hairpin RNA Gene Silencing of Prolyl Hydroxylase-2 with a Minicircle Vector Improves Neovascularization of Hindlimb Ischemia

    Article • Human Gene Therapy, January 2014, Mary Ann Liebert Inc

    Professor Paul HA Quax

  117. Soluble ST2 levels are not associated with secondary cardiovascular events and vulnerable plaque phenotype in patients with carotid artery stenosis

    Article • Atherosclerosis, November 2013, Elsevier

    Professor Paul HA Quax

  118. The 14q32 MicroRNA-487b Targets the Antiapoptotic Insulin Receptor Substrate 1 in Hypertension-Induced Remodeling of the Aorta

    Article • Annals of Surgery, November 2013, Wolters Kluwer Health

    Professor Paul HA Quax

  119. C57BL/6 NK cell gene complex is crucially involved in vascular remodeling

    Article • Journal of Molecular and Cellular Cardiology, November 2013, Elsevier

    Victor van Hinsbergh, Professor Paul HA Quax

  120. Quaking, an RNA-Binding Protein, Is a Critical Regulator of Vascular Smooth Muscle Cell Phenotype

    Article • Circulation Research, October 2013, Wolters Kluwer Health

    Professor Paul HA Quax

  121. An Unexpected Intriguing Effect of Toll-Like Receptor Regulator RP105 (CD180) on Atherosclerosis Formation With Alterations on B-Cell Activation

    Article • Arteriosclerosis Thrombosis and Vascular Biology, October 2013, Wolters Kluwer Health

    Professor Paul HA Quax

  122. T-cell co-stimulation by CD28–CD80/86 and its negative regulator CTLA-4 strongly influence accelerated atherosclerosis development

    Article • International Journal of Cardiology, October 2013, Elsevier

    Professor Paul HA Quax

  123. Pathway Analysis Using Genome-Wide Association Study Data for Coronary Restenosis – A Potential Role for the PARVB Gene

    Article • PLoS ONE, August 2013, PLOS

    Professor Paul HA Quax

  124. Anti-apoptotic Serpins as Therapeutics in Cardiovascular Diseases

    Article • Cardiovascular & Haematological Disorders - Drug Targets, July 2013, Bentham Science Publishers

    Professor Paul HA Quax

  125. TLR Accessory Molecule RP105 (CD180) Is Involved in Post-Interventional Vascular Remodeling and Soluble RP105 Modulates Neointima Formation

    Article • PLoS ONE, July 2013, PLOS

    Professor Paul HA Quax

  126. Lysine Acetyltransferase PCAF Is a Key Regulator of Arteriogenesis

    Article • Arteriosclerosis Thrombosis and Vascular Biology, June 2013, Wolters Kluwer Health

    Professor Paul HA Quax

  127. Mast cells in human carotid atherosclerotic plaques are associated with intraplaque microvessel density and the occurrence of future cardiovascular events

    Article • European Heart Journal, June 2013, European Society of Cardiology

    Professor Paul HA Quax

  128. Protease-Activated Receptor (PAR)2, but Not PAR1, Is Involved in Collateral Formation and Anti-Inflammatory Monocyte Polarization in a Mouse Hind Limb Ischemia Model

    Article • PLoS ONE, April 2013, PLOS

    Professor Paul HA Quax, Arnold Spek

  129. A small molecule approach to engineering vascularized tissue

    Article • Biomaterials, April 2013, Elsevier

    Professor Paul HA Quax

  130. Arteriovenous access failure: more than just intimal hyperplasia?

    Article • Nephrology Dialysis Transplantation, March 2013, Oxford University Press (OUP)

    Professor Paul HA Quax

  131. Lysophosphatidic acid triggers mast cell-driven atherosclerotic plaque destabilization by increasing vascular inflammation

    Article • Journal of Lipid Research, February 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Paul HA Quax

  132. Complement factor C5a as mast cell activator mediates vascular remodelling in vein graft disease

    Article • Cardiovascular Research, October 2012, European Society of Cardiology

    Professor Paul HA Quax

  133. Plaque Rupture Complications in Murine Atherosclerotic Vein Grafts Can Be Prevented by TIMP-1 Overexpression

    Article • PLoS ONE, October 2012, PLOS

    Professor Paul HA Quax

  134. Shear induced collateral artery growth modulated by endoglin but not by ALK1

    Article • Journal of Cellular and Molecular Medicine, September 2012, Wiley

    Professor Paul HA Quax

  135. Epigenetic control of CCR5 transcript levels in immune cells and modulation by small molecules inhibitors

    Article • Journal of Cellular and Molecular Medicine, July 2012, Wiley

    Professor Paul HA Quax

  136. Blocking Toll-Like Receptors 7 and 9 Reduces Postinterventional Remodeling via Reduced Macrophage Activation, Foam Cell Formation, and Migration

    Article • Arteriosclerosis Thrombosis and Vascular Biology, May 2012, Wolters Kluwer Health

    Professor Paul HA Quax

  137. Mast cell activation via complement factor C5a modulates vein graft remodeling and accelerated atherosclerosis

    Article • Vascular Pharmacology, May 2012, Elsevier

    Professor Paul HA Quax

  138. Spontaneous plaque disruptions, dissection, erosion and intraplaque hemorrhage in murine vein grafts can be attenuated by TIMP-1 overexpression

    Article • Vascular Pharmacology, May 2012, Elsevier

    Professor Paul HA Quax

  139. Systemic MCP1/CCR2 blockade and leukocyte specific MCP1/CCR2 inhibition affect aortic aneurysm formation differently

    Article • Vascular Pharmacology, May 2012, Elsevier

    Professor Paul HA Quax

  140. Annexin A5 prevents post-interventional accelerated atherosclerosis development in a dose-dependent fashion in mice

    Article • Atherosclerosis, April 2012, Elsevier

    Professor Paul HA Quax

  141. Cardiovascular metabolic syndrome: mediators involved in the pathophysiology from obesity to coronary heart disease

    Article • Biomarkers in Medicine, February 2012, Future Medicine

    Professor Paul HA Quax

  142. Future potential biomarkers for postinterventional restenosis and accelerated atherosclerosis

    Article • Biomarkers in Medicine, February 2012, Future Medicine

    Professor Paul HA Quax

  143. A limited role for regulatory T cells in post-ischemic neovascularization

    Article • Journal of Cellular and Molecular Medicine, January 2012, Wiley

    Professor Tim D Sparwasser, Professor Paul HA Quax

  144. C1-esterase inhibitor protects against early vein graft remodeling under arterial blood pressure

    Article • Atherosclerosis, January 2012, Elsevier

    Professor Paul HA Quax, Victor van Hinsbergh

  145. Molecular Imaging of Bone Marrow Mononuclear Cell Survival and Homing in Murine Peripheral Artery Disease

    Article • JACC Cardiovascular Imaging, January 2012, Elsevier

    Professor Paul HA Quax

  146. Restenosis after PCI. Part 2: prevention and therapy

    Article • Nature Reviews Cardiology, October 2011, Springer Science + Business Media

    Professor Paul HA Quax

  147. Restenosis after PCI. Part 1: pathophysiology and risk factors

    Article • Nature Reviews Cardiology, September 2011, Springer Science + Business Media

    Professor Paul HA Quax

  148. SNPs in MicroRNA Binding Sites in 3′-UTRs of RAAS Genes Influence Arterial Blood Pressure and Risk of Myocardial Infarction

    Article • American Journal of Hypertension, September 2011, Oxford University Press (OUP)

    Professor Paul HA Quax

  149. MicroRNA-126 modulates endothelial SDF-1 expression and mobilization of Sca-1+/Lin− progenitor cells in ischaemia

    Article • Cardiovascular Research, August 2011, European Society of Cardiology

    Professor Paul HA Quax

  150. Galectin-2 expression is dependent on the rs7291467 polymorphism and acts as an inhibitor of arteriogenesis

    Article • European Heart Journal, August 2011, European Society of Cardiology

    Professor Paul HA Quax

  151. Clinical performance of drug-eluting stents with biodegradable polymeric coating: a meta-analysis and systematic review

    Article • EuroIntervention, August 2011, Europa Digital & Publishing

    Professor Paul HA Quax

  152. The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions

    Article • EMBO Molecular Medicine, July 2011, EMBO

    Professor Paul HA Quax

  153. Clinical Applications of the Urokinase Receptor (uPAR) for Cancer Patients

    Article • Current Pharmaceutical Design, June 2011, Bentham Science Publishers

    Professor Paul HA Quax, Dr. CFM Sier

  154. Toll-Like Receptor 4 Is Involved in Human and Mouse Vein Graft Remodeling, and Local Gene Silencing Reduces Vein Graft Disease in Hypercholesterolemic APOE*3Leiden Mice

    Article • Arteriosclerosis Thrombosis and Vascular Biology, May 2011, Wolters Kluwer Health

    Professor Paul HA Quax

  155. Lack of Fibronectin-EDA Promotes Survival and Prevents Adverse Remodeling and Heart Function Deterioration After Myocardial Infarction

    Article • Circulation Research, March 2011, Wolters Kluwer Health

    Professor Paul HA Quax

  156. T-cell-pre-stimulated Monocytes Promote Neovascularisation in a Murine Hind Limb Ischaemia Model

    Article • European Journal of Vascular and Endovascular Surgery, March 2011, Elsevier

    Professor Paul HA Quax

  157. Variations in Surgical Procedures for Hind Limb Ischaemia Mouse Models Result in differences in Collateral Formation

    Article • European Journal of Vascular and Endovascular Surgery, December 2010, Elsevier

    Professor Paul HA Quax

  158. Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies

    Article • Heart, November 2010, BMJ

    Professor Paul HA Quax

  159. Annexin A5 Therapy Attenuates Vascular Inflammation and Remodeling and Improves Endothelial Function in Mice

    Article • Arteriosclerosis Thrombosis and Vascular Biology, October 2010, Wolters Kluwer Health

    Professor Paul HA Quax

  160. 6-Mercaptopurine Inhibits Atherosclerosis in Apolipoprotein E*3-Leiden Transgenic Mice Through Atheroprotective Actions on Monocytes and Macrophages

    Article • Arteriosclerosis Thrombosis and Vascular Biology, August 2010, Wolters Kluwer Health

    Professor Paul HA Quax

  161. Systemic MCP1/CCR2 blockade and leukocyte specific MCP1/CCR2 inhibition affect aortic aneurysm formation differently

    Article • Atherosclerosis, July 2010, Elsevier

    Professor Paul HA Quax

  162. A novel urokinase receptor-targeted inhibitor for plasmin and matrix metalloproteinases suppresses vein graft disease

    Article • Cardiovascular Research, June 2010, European Society of Cardiology

    Professor Paul HA Quax

  163. Epigenetics in atherosclerosis and inflammation

    Article • Journal of Cellular and Molecular Medicine, June 2010, Wiley

    Professor Paul HA Quax

  164. Genetic determinants of adverse outcome (restenosis, malapposition and thrombosis) after stent implantation

    Article • Interventional Cardiology, April 2010, OMICS Publishing Group

    Professor Paul HA Quax

  165. Strain-dependent susceptibility for hypertension in mice resides in the natural killer gene complex

    Article • AJP Heart and Circulatory Physiology, April 2010, American Physiological Society

    Professor Paul HA Quax

  166. GALECTIN-2 EXPRESSION IS DEPENDENT ON THE 3279C>T POLYMORPHISM AND IS ASSOCIATED WITH ARTERIOGENESIS IN PATIENTS WITH CORONARY ARTERY DISEASE

    Article • Journal of the American College of Cardiology, March 2010, Elsevier

    Professor Paul HA Quax

  167. In vivo suppression of vein graft disease by nonviral, electroporation-mediated, gene transfer of tissue inhibitor of metalloproteinase-1 linked to the amino terminal fragment of urokinase (TIMP-1.ATF), a cell-surface directed matrix metalloproteinase ...

    Article • Journal of Vascular Surgery, February 2010, Elsevier

    Professor Paul HA Quax

  168. Vitamin D receptor: a new risk marker for clinical restenosis after percutaneous coronary intervention

    Article • Expert Opinion on Therapeutic Targets, January 2010, Informa Healthcare

    Professor Paul HA Quax

  169. Local lentiviral short hairpin RNA silencing of CCR2 inhibits vein graft thickening in hypercholesterolemic apolipoprotein E3-Leiden mice

    Article • Journal of Vascular Surgery, July 2009, Elsevier

    Professor Paul HA Quax

  170. Critical Role of Tissue Kallikrein in Vessel Formation and Maturation

    Article • Arteriosclerosis Thrombosis and Vascular Biology, May 2009, Wolters Kluwer Health

    Professor Paul HA Quax, Associate Professor Rajesh G Katare, Luciola Barcelos

  171. Antagomir-mediated silencing of endothelial cell specific microRNA-126 impairs ischemia-induced angiogenesis

    Article • Journal of Cellular and Molecular Medicine, December 2008, Wiley

    Professor Paul HA Quax

  172. Epigenetic histone acetylation modifiers in vascular remodelling: new targets for therapy in cardiovascular disease

    Article • European Heart Journal, September 2008, European Society of Cardiology

    Professor Paul HA Quax

  173. Insights into mechanisms behind arteriogenesis: what does the future hold?

    Article • Journal of Leukocyte Biology, August 2008, Wiley

    Professor Paul HA Quax

  174. Increased infiltration of Chlamydophila pneumoniae in the vessel wall of human veins after perfusion

    Article • European Journal of Clinical Investigation, July 2008, Wiley

    Professor Paul HA Quax

  175. Vascular Growth in Ischemic Limbs: A Review of Mechanisms and Possible Therapeutic Stimulation

    Article • Annals of Vascular Surgery, July 2008, Elsevier

    Professor Paul HA Quax

  176. Proteomic and Metabolomic Analysis of Smooth Muscle Cells Derived From the Arterial Media and Adventitial Progenitors of Apolipoprotein E–Deficient Mice

    Article • Circulation Research, May 2008, Wolters Kluwer Health

    Professor Paul HA Quax, Manuel Mayr

  177. Nur77 modulates hepatic lipid metabolism through suppression of SREBP1c activity

    Article • Biochemical and Biophysical Research Communications, February 2008, Elsevier

    Professor Paul HA Quax, Dr Thijs W Pols

  178. Dexamethasone-eluting stents for the prevention of in-stent restenosis: Evidence for a differential effect in insulin-dependent and non-insulin-dependent diabetic patients

    Article • International Journal of Cardiology, February 2008, Elsevier

    Professor Paul HA Quax

  179. Toll-Like Receptor 4 Mediates Maladaptive Left Ventricular Remodeling and Impairs Cardiac Function After Myocardial Infarction

    Article • Circulation Research, February 2008, Wolters Kluwer Health

    Professor Paul HA Quax

  180. ProlongedIn VivoGene Silencing by Electroporation-Mediated Plasmid Delivery of Small Interfering RNA

    Article • Human Gene Therapy, September 2007, Mary Ann Liebert Inc

    Professor Paul HA Quax

  181. Vaccination Against VEGFR2 Attenuates Initiation and Progression of Atherosclerosis

    Article • Arteriosclerosis Thrombosis and Vascular Biology, September 2007, Wolters Kluwer Health

    Professor Paul HA Quax

  182. Natural Killer Cells and CD4+ T-Cells Modulate Collateral Artery Development

    Article • Arteriosclerosis Thrombosis and Vascular Biology, August 2007, Wolters Kluwer Health

    Victor van Hinsbergh, Professor Paul HA Quax

  183. The effect of interleukin-10 knock-out and overexpression on neointima formation in hypercholesterolemic APOE*3-Leiden mice

    Article • Atherosclerosis, August 2007, Elsevier

    Professor Paul HA Quax

  184. Sirolimus and paclitaxel provoke different vascular pathological responses after local delivery in a murine model for restenosis on underlying atherosclerotic arteries

    Article • Heart, August 2007, BMJ

    Professor Paul HA Quax

  185. Expression of Vascular Endothelial Growth Factor, Stromal Cell-Derived Factor-1, and CXCR4 in Human Limb Muscle With Acute and Chronic Ischemia

    Article • Arteriosclerosis Thrombosis and Vascular Biology, June 2007, Wolters Kluwer Health

    Victor van Hinsbergh, Professor Paul HA Quax

  186. Activation of the Innate Immune System in Atherosclerotic Disease

    Article • Current Pharmaceutical Design, April 2007, Bentham Science Publishers

    Professor Paul HA Quax

  187. Activation of Nuclear Receptor Nur77 by 6-Mercaptopurine Protects Against Neointima Formation

    Article • Circulation, January 2007, Wolters Kluwer Health

    Professor Paul HA Quax

  188. Wnt but Not BMP Signaling Is Involved in the Inhibitory Action of Sclerostin on BMP‐Stimulated Bone Formation

    Article • Journal of Bone and Mineral Research, January 2007, Oxford University Press (OUP)

    Professor Paul HA Quax, Professor Marcel Karperien

  189. Inhibition of neointima formation by local delivery of estrogen receptor alpha and beta specific agonists

    Article • Cardiovascular Research, January 2007, European Society of Cardiology

    Professor Paul HA Quax

  190. The influence of established genetic variation in the haemostatic system on clinical restenosis after percutaneous coronary interventions

    Article • Thrombosis and Haemostasis, January 2007, Schattauer GmbH

    Professor Paul HA Quax

  191. Inhibition of Complement Component C3 Reduces Vein Graft Atherosclerosis in Apolipoprotein E3–Leiden Transgenic Mice

    Article • Circulation, December 2006, Wolters Kluwer Health

    Professor Paul HA Quax

  192. Interleukin 10: a new risk marker for the development of restenosis after percutaneous coronary intervention

    Article • Genes & Immunity, November 2006, Springer Science + Business Media

    Professor Paul HA Quax

  193. Murine models of myocardial and limb ischemia: Diagnostic end-points and relevance to clinical problems

    Article • Vascular Pharmacology, November 2006, Elsevier

    Professor Paul HA Quax

  194. Generation of a novel replication-incompetent adenoviral vector derived from human adenovirus type 49: manufacture on PER.C6 cells, tropism and immunogenicity

    Article • Journal of General Virology, October 2006, Society for General Microbiology

    Professor Paul HA Quax

  195. Impaired pathological and transcriptional responses after local delivery of paclitaxel, but not rapamycin, to abolish restenosis

    Article • Vascular Pharmacology, September 2006, Elsevier

    Professor Paul HA Quax

  196. Activation of nuclear receptor Nur77 by 6-mercaptopurine inhibits smooth muscle cell proliferation

    Article • Vascular Pharmacology, September 2006, Elsevier

    Professor Paul HA Quax

  197. Upregulation of SDF1 and CXCR4 in ischemic tissue of patients with severe peripheral arterial disease

    Article • Vascular Pharmacology, September 2006, Elsevier

    Professor Paul HA Quax

  198. Local lentiviral shRNA silencing of CCR2 inhibits vein graft thickening in hypercholesterolemic ApoE3Leiden mice

    Article • Vascular Pharmacology, September 2006, Elsevier

    Professor Paul HA Quax

  199. Non-viral electrodelivery of BMP-2 cDNA reduces intimal hyperplasia, but enfeebles vessel wall integrity of vein grafts in vivo

    Article • Vascular Pharmacology, September 2006, Elsevier

    Professor Paul HA Quax

  200. Natural killer en CD4+ T-lymphocytes modulate collateral artery growth

    Article • Vascular Pharmacology, September 2006, Elsevier

    Professor Paul HA Quax

  201. Endothelial proliferation, migration and transformation during the initial phases of intimal formation

    Article • Vascular Pharmacology, September 2006, Elsevier

    Professor Paul HA Quax

  202. Anti–MCP-1 Gene Therapy Inhibits Vascular Smooth Muscle Cells Proliferation and Attenuates Vein Graft Thickening Both In Vitro and In Vivo

    Article • Arteriosclerosis Thrombosis and Vascular Biology, September 2006, Wolters Kluwer Health

    Professor Paul HA Quax

  203. TR3 Nuclear Orphan Receptor Prevents Cyclic Stretch-Induced Proliferation of Venous Smooth Muscle Cells

    Article • American Journal Of Pathology, June 2006, Elsevier

    Professor Paul HA Quax

  204. Hypercholesterolemia Reduces Collateral Artery Growth More Dominantly Than Hyperglycemia or Insulin Resistance in Mice

    Article • Arteriosclerosis Thrombosis and Vascular Biology, June 2006, Wolters Kluwer Health

    Professor Paul HA Quax

  205. Treatment with Intramuscular Vascular Endothelial Growth Factor Gene Compared with Placebo for Patients with Diabetes Mellitus and Critical Limb Ischemia: A Double-Blind Randomized Trial

    Article • Human Gene Therapy, June 2006, Mary Ann Liebert Inc

    Professor Paul HA Quax

  206. Drug-eluting stents studies in mice: Do we need atherosclerosis to study restenosis?

    Article • Vascular Pharmacology, May 2006, Elsevier

    Professor Paul HA Quax

  207. Short-term dexamethasone treatment inhibits vein graft thickening in hypercholesterolemic ApoE3Leiden transgenic mice

    Article • Journal of Vascular Surgery, April 2006, Elsevier

    Professor Paul HA Quax

  208. Pericellular Proteases in Angiogenesis and Vasculogenesis

    Article • Arteriosclerosis Thrombosis and Vascular Biology, April 2006, Wolters Kluwer Health

    Victor van Hinsbergh, Professor Paul HA Quax

  209. Human CD46-transgenic mice in studies involving replication-incompetent adenoviral type 35 vectors

    Article • Journal of General Virology, February 2006, Society for General Microbiology

    Professor Paul HA Quax

  210. 596. A Novel Replication Incompetent Human Subgroup D Adenoviral Vector Based on Type 49: Manufacture on PER.C6®, Cell Tropism and Immunogenicity

    Article • Molecular Therapy, January 2006, Elsevier

    Professor Paul HA Quax

  211. Histopathologic alterations following local delivery of dexamethasone to inhibit restenosis in murine arteries

    Article • Cardiovascular Research, December 2005, European Society of Cardiology

    Professor Paul HA Quax

  212. Tumor necrosis factor-  plays an important role in restenosis development

    Article • The FASEB Journal, December 2005, Federation of American Societies For Experimental Biology (FASEB)

    Professor Paul HA Quax

  213. Genetic Inflammatory Factors Predict Restenosis After Percutaneous Coronary Interventions

    Article • Circulation, October 2005, Wolters Kluwer Health

    Professor Paul HA Quax

  214. Tissue Inhibitor of Metalloproteinase-3 Expression from an Oncolytic Adenovirus Inhibits Matrix Metalloproteinase ActivityIn vivowithout Affecting Antitumor Efficacy in Malignant Glioma

    Article • Cancer Research, October 2005, American Association for Cancer Research (AACR)

    Professor Paul HA Quax

  215. Involvement of furin-like proprotein convertases in the arterial response to injury

    Article • Cardiovascular Research, October 2005, European Society of Cardiology

    Professor Paul HA Quax

  216. Lipoprotein Lipase Gene Polymorphisms and the Risk of Target Vessel Revascularization After Percutaneous Coronary Intervention

    Article • Journal of the American College of Cardiology, September 2005, Elsevier

    Professor Paul HA Quax

  217. Local perivascular delivery of anti-restenotic agents from a drug-eluting poly(-caprolactone) stent cuff

    Article • Biomaterials, September 2005, Elsevier

    Professor Paul HA Quax

  218. Drug-eluting stents: results, promises and problems

    Article • International Journal of Cardiology, March 2005, Elsevier

    Professor Paul HA Quax

  219. Novel Replication-Incompetent Vector Derived from Adenovirus Type 11 (Ad11) for Vaccination and Gene Therapy: Low Seroprevalence and Non-Cross-Reactivity with Ad5

    Article • Journal of Virology, December 2004, ASM Journals

    Professor Paul HA Quax

  220. Involvement of Membrane-Type Matrix Metalloproteinases (MT-MMPs) in Capillary Tube Formation by Human Endometrial Microvascular Endothelial Cells: Role of MT3-MMP

    Article • The Journal of Clinical Endocrinology & Metabolism, November 2004, Endocrine Society

    Professor Paul HA Quax, Victor van Hinsbergh

  221. Vascular Endothelial Growth Factor Overexpression in Ischemic Skeletal Muscle Enhances Myoglobin Expression In Vivo

    Article • Circulation Research, July 2004, Wolters Kluwer Health

    Professor Paul HA Quax

  222. DEXAMETHASONE REDUCES INTIMAL HYPERPLASIA AND VEIN GRAFT REMODELLING IN APOE3LEIDEN MICE

    Article • Cardiovascular Pathology, May 2004, Elsevier

    Professor Paul HA Quax

  223. TOLL-LIKE RECEPTOR 4 IS INVOLVED IN THE REGULATION OF VASCULAR REMODELING

    Article • Cardiovascular Pathology, May 2004, Elsevier

    Professor Paul HA Quax

  224. HAMPERED COLLATERAL VESSEL DEVELOPMENT IN HYPERLIPIDAEMIC APOE3*LEIDEN TRANSGENIC MICE, BUT NOT IN MOUSE MODELS OF TYPE I AND II DIABETES

    Article • Cardiovascular Pathology, May 2004, Elsevier

    Professor Paul HA Quax

  225. VASCULAR ENDOTHELIAL GROWTH FACTOR OVEREXPRESSION IN ISCHAEMIC SKELETAL MUSCLE ENHANCES MYOGLOBIN EXPRESSION IN VIVO

    Article • Cardiovascular Pathology, May 2004, Elsevier

    Professor Paul HA Quax

  226. EXPRESSION PATTERNS OF VEGF AND VEGF RECEPTORS IN ISCHAEMIC SKELETAL MUSCLE OF PATIENTS AFTER LIMB AMPUTATION

    Article • Cardiovascular Pathology, May 2004, Elsevier

    Professor Paul HA Quax

  227. IN VIVO, NON-VIRAL LOCAL GENE DELIVERY TO MOUSE FEMORAL ARTERY BY ELECTROPORATION: A PROMISING TOOL TO INVESTIGATE POST-ANGIOPLASTY RESTENOSIS

    Article • Cardiovascular Pathology, May 2004, Elsevier

    Professor Paul HA Quax

  228. Ingrowth of aorta wall into stent grafts impregnated with basic fibroblast growth factor: a porcine in vivo study of blood vessel prosthesis healing

    Article • Journal of Vascular Surgery, April 2004, Elsevier

    Professor Paul HA Quax

  229. Toll-Like Receptor 4 Is Involved in Outward Arterial Remodeling

    Article • Circulation, January 2004, Wolters Kluwer Health

    Professor Paul HA Quax

  230. TR3 Orphan Receptor Is Expressed in Vascular Endothelial Cells and Mediates Cell Cycle Arrest

    Article • Arteriosclerosis Thrombosis and Vascular Biology, September 2003, Wolters Kluwer Health

    Professor Paul HA Quax

  231. Replication-Deficient Human Adenovirus Type 35 Vectors for Gene Transfer and Vaccination: Efficient Human Cell Infection and Bypass of Preexisting Adenovirus Immunity

    Article • Journal of Virology, August 2003, ASM Journals

    Professor Paul HA Quax

  232. Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3

    Article • Gene Therapy, January 2003, Springer Science + Business Media

    Professor Paul HA Quax

  233. Adenoviral delivery of a constitutively active retinoblastoma mutant inhibits neointima formation in a human explant model for vein graft disease

    Article • Vascular Pharmacology, December 2002, Elsevier

    Professor Paul HA Quax

  234. Ingrowth of aorta vascular cells into basic fibroblast growth factor-impregnated vascular prosthesis material: A porcine and human in vitro study on blood vessel prosthesis healing

    Article • Journal of Vascular Surgery, December 2002, Elsevier

    Professor Paul HA Quax

  235. Gene Transfer of the Urokinase-Type Plasminogen Activator Receptor-Targeted Matrix Metalloproteinase Inhibitor TIMP-1.ATF Suppresses Neointima Formation More Efficiently Than Tissue Inhibitor of Metalloproteinase-1

    Article • Circulation Research, November 2002, Wolters Kluwer Health

    Professor Paul HA Quax

  236. In Vivo Evidence for a Role of Toll-Like Receptor 4 in the Development of Intimal Lesions

    Article • Circulation, October 2002, Wolters Kluwer Health

    Professor Paul HA Quax

  237. Accelerated Atherosclerosis and Calcification in Vein Grafts

    Article • Circulation Research, October 2002, Wolters Kluwer Health

    Professor Paul HA Quax

  238. Membrane-type matrix metalloproteinase-mediated angiogenesis in a fibrin-collagen matrix

    Article • Blood, September 2002, American Society of Hematology

    Professor Paul HA Quax

  239. Inhibition of Accelerated Atherosclerosis in Vein Grafts by Placement of External Stent in ApoE*3-Leiden Transgenic Mice

    Article • Arteriosclerosis Thrombosis and Vascular Biology, September 2002, Wolters Kluwer Health

    Professor Paul HA Quax

  240. Adenoviral Activin A Expression Prevents Intimal Hyperplasia in Human and Murine Blood Vessels by Maintaining the Contractile Smooth Muscle Cell Phenotype

    Article • Circulation Research, May 2002, Wolters Kluwer Health

    Professor Paul HA Quax

  241. VLDL receptor deficiency enhances intimal thickening after vascular injury but does not affect atherosclerotic lesion area

    Article • Atherosclerosis, May 2002, Elsevier

    Professor Paul HA Quax

  242. Exploiting the Natural Diversity in Adenovirus Tropism for Therapy and Prevention of Disease

    Article • Journal of Virology, May 2002, ASM Journals

    Professor Paul HA Quax

  243. Activation of toll-like receptor 4 in adventitial cells by lipopolysaccharide induces neointima formation in a mouse model

    Article • Journal of the American College of Cardiology, March 2002, Elsevier

    Professor Paul HA Quax

  244. Urokinase-Receptor/Integrin Complexes Are Functionally Involved in Adhesion and Progression of Human Breast Cancer in Vivo

    Article • American Journal Of Pathology, September 2001, Elsevier

    Professor Paul HA Quax, Professor Marcel Karperien

  245. Adenovirus-mediated transfer of the 39 kD receptor-associated protein increases fibrinolytic capacity

    Article • Kidney International, July 2001, Elsevier

    Professor Paul HA Quax

  246. Improved Adenovirus Vectors for Infection of Cardiovascular Tissues

    Article • Journal of Virology, April 2001, ASM Journals

    Professor Paul HA Quax

  247. In vivo suppression of restenosis in balloon-injured rat carotid artery by adenovirus-mediated gene transfer of the cell surface-directed plasmin inhibitor ATF.BPTI

    Article • Gene Therapy, April 2001, Springer Science + Business Media

    Professor Paul HA Quax

  248. Simultaneous Detection of NOS-3 Protein Expression and Nitric Oxide Production Using a Flow Cytometer

    Article • Analytical Biochemistry, March 2001, Elsevier

    Professor Paul HA Quax

  249. Adenoviral Expression of a Urokinase Receptor–Targeted Protease Inhibitor Inhibits Neointima Formation in Murine and Human Blood Vessels

    Article • Circulation, January 2001, Wolters Kluwer Health

    Professor Paul HA Quax

  250. Accelerated Atherosclerosis by Placement of a Perivascular Cuff and a Cholesterol-Rich Diet in ApoE*3Leiden Transgenic Mice

    Article • Circulation Research, August 2000, Wolters Kluwer Health

    Dr Hans M Princen, Victor van Hinsbergh, Professor Paul HA Quax

  251. Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of a cell surface-targeted plasmin inhibitor

    Article • Arthritis & Rheumatism, August 2000, Wiley

    Professor Paul HA Quax

  252. Article • Clinical & Experimental Metastasis, January 2000, Springer Science + Business Media

    Professor Paul HA Quax

  253. Fibrinolytic activity of human mesothelial cells is counteracted by rapid uptake of tissue-type plasminogen activator

    Article • Kidney International, January 1999, Elsevier

    Professor Paul HA Quax

  254. Mitogenic Effects of Urokinase on Melanoma Cells Are Independent of High Affinity Binding to the Urokinase Receptor

    Article • Journal of Biological Chemistry, December 1998, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Paul HA Quax

  255. Binding of Human Urokinase-Type Plasminogen Activator to Its Receptor : Residues Involved in Species Specificity and Binding

    Article • Arteriosclerosis Thrombosis and Vascular Biology, May 1998, Wolters Kluwer Health

    Victor van Hinsbergh, Professor Paul HA Quax

  256. Role of Endothelial Plasminogen Activators in Fibrinolysis and Repair-Associated Angiogenesis

    Article • January 1998, Springer Science + Business Media

    Professor Paul HA Quax, Victor van Hinsbergh

  257. Plasminogen activator and matrix metalloproteinase production and extracellular matrix degradation by rat prostate cancer cells in vitro: Correlation with metastatic behavior in vivo

    Article • The Prostate, August 1997, Wiley

    Professor Paul HA Quax

  258. Apoptin induces apoptosis in human transformed and malignant cells but not in normal cells

    Article • Proceedings of the National Academy of Sciences, May 1997, Proceedings of the National Academy of Sciences

    Professor Paul HA Quax

  259. Different effects of lipopolysaccharide on plasminogen activator inhibitor-1 production in aortic media in vivo and in culture

    Article • Journal of Thrombosis and Thrombolysis, September 1996, Springer Science + Business Media

    Professor Paul HA Quax

  260. Effects of infection with recombinant adenovirus on human vascular endothelial and smooth muscle cells

    Article • Fibrinolysis and Proteolysis, June 1996, Elsevier

    Professor Paul HA Quax

  261. Urokinase and tissue-type plasminogen activator stimulate human vascular smooth muscle cell migration

    Article • Fibrinolysis and Proteolysis, June 1996, Elsevier

    Professor Paul HA Quax

  262. Regulation of plasminogen activation, matrix metalloproteinases and urokinase‐type plasminogen activator‐mediated extracellular matrix degradation in human osteosarcoma cell line MG63 by interleukin‐1 alpha

    Article • Journal of Bone and Mineral Research, September 1995, Oxford University Press (OUP)

    Professor Paul HA Quax

  263. Differential Regulation of Plasminogen Activation in Normal Keratinocytes and SCC-4 Cells by Fibroblasts

    Article • Journal of Investigative Dermatology, March 1995, Elsevier

    Professor Paul HA Quax

  264. Components of the plasminogen activation system in uveal melanoma—a clinico‐pathological study

    Article • The Journal of Pathology, January 1995, Wiley

    Professor Paul HA Quax

  265. Inactive urokinase and increased levels of its inhibitor type 1 in colorectal cancer liver metastasis

    Article • Gastroenterology, November 1994, Elsevier

    Professor Paul HA Quax, Dr. CFM Sier

  266. Tumor cells secrete an Angiogenic factor that stimulates basic fibroblast growth factor and Urokinase expression in Vascular Endothelial cells

    Article • Journal of Cellular Physiology, October 1994, Wiley

    Professor Paul HA Quax

  267. Plasminogen activators are involved in keratinocyte and fibroblast migration in wounded cultures in vitro

    Article • Fibrinolysis and Proteolysis, July 1994, Elsevier

    Professor Paul HA Quax

  268. Cultured rat aortic vascular smooth muscle cells digest naturally produced extracellular matrix. Involvement of plasminogen-dependent and plasminogen-independent pathways.

    Article • Circulation Research, August 1992, Wolters Kluwer Health

    Professor Paul HA Quax

  269. Modulation of activities and RNA level of the components of the plasminogen activation system during fusion of human myogenic satellite cells in vitro

    Article • Developmental Biology, May 1992, Elsevier

    Professor Paul HA Quax

  270. Metastatic behavior of human melanoma cell lines in nude mice correlates with urokinase-type plasminogen activator, its type-1 inhibitor, and urokinase-mediated matrix degradation

    Article • The Journal of Cell Biology, October 1991, Rockefeller University Press

    Professor Paul HA Quax

  271. Involvement of aspartic and glutamic residues in kringle-2 of tissue-type plasminogen activator in lysine binding, fibrin binding and stimulation of activity as revealed by chemical modification and oligonucleotide-directed mutagenesis

    Article • Protein Engineering Design and Selection, January 1990, Oxford University Press (OUP)

    Professor Paul HA Quax