All Stories

  1. Non-coding RNAs as therapeutic targets and biomarkers in ischaemic heart disease
  2. MyoLoop: Redefining cardiac research with advanced tissue simulation
  3. Regulation of BACH1 by hemin improves cardiac function in a mouse model of myocardial infarction
  4. The role of cardiac pericytes in health and disease: therapeutic targets for myocardial infarction
  5. Non-neuronal cholinergic system delays cardiac remodelling in type 1 diabetes
  6. Cardiac Progenitor Cells and Adipocyte Stem Cells from Same Patients Exhibit In Vitro Functional Differences
  7. Stage-specific regulation of signalling pathways to differentiate pluripotent stem cells to cardiomyocytes with ventricular lineage
  8. Cardiac pericyte reprogramming by MEK inhibition promotes arteriologenesis and angiogenesis of the ischemic heart
  9. Upregulated miR-200c is associated with downregulation of the functional receptor for severe acute respiratory syndrome coronavirus 2 ACE2 in individuals with obesity
  10. Reactive Oxygen Species-Mediated Diabetic Heart Disease: Mechanisms and Therapies
  11. METTL3 Regulates Angiogenesis by Modulating let-7e-5p and miRNA-18a-5p Expression in Endothelial Cells
  12. Upregulated miR-200c may increase the risk of obese individuals to severe COVID-19
  13. Elevated myocardial fructose and sorbitol levels are associated with diastolic dysfunction in diabetic patients, and cardiomyocyte lipid inclusions in vitro
  14. A study on polymorphic forms of rifampicin for inhaled high dose delivery in tuberculosis treatment
  15. Combination of Cardiac Progenitor Cells From the Right Atrium and Left Ventricle Exhibits Synergistic Paracrine Effects In Vitro
  16. Shear force sensing of epithelial Na + channel (ENaC) relies on N -glycosylated asparagines in the palm and knuckle domains of αENaC
  17. Stress axis and osteopathy: A dual hormone approach
  18. Early dysregulation of cardiac-specific microRNA-208a is linked to maladaptive cardiac remodelling in diabetic myocardium
  19. The non-neuronal cholinergic system in the heart: A comprehensive review
  20. Acute Weight Loss Restores Dysregulated Circulating MicroRNAs in Individuals Who Are Obese
  21. Molecular mechanism of diabetic cardiomyopathy and modulation of microRNA function by synthetic oligonucleotides
  22. Concise Review: Challenges in Regenerating the Diabetic Heart: A Comprehensive Review
  23. The diagnostic sensitivity of circulating cardio-enriched microRNAs is increased after normalization of high-density lipoprotein levels
  24. Progenitor cells from atria, ventricle and peripheral blood of the same patients exhibit functional differences associated with cardiac repair
  25. Reply to the letter to editor “Autophagy may be impelled by collected fatty acids in type 2 diabetic myocardial cells”
  26. Exercise mediated protection of diabetic heart through modulation of microRNA mediated molecular pathways
  27. Down-regulation of proangiogenic microRNA-126 and microRNA-132 are early modulators of diabetic cardiac microangiopathy
  28. Ghrelin Promotes Functional Angiogenesis in a Mouse Model of Critical Limb Ischemia Through Activation of Proangiogenic MicroRNAs
  29. Differential expression pattern of cardiovascular microRNAs in the human type-2 diabetic heart with normal ejection fraction
  30. Type-2 diabetes increases autophagy in the human heart through promotion of Beclin-1 mediated pathway
  31. Data supporting the activation of autophagy genes in the diabetic heart
  32. Haematological adaptations to High Intensity Interval Training (HIIT) in temperate and hot environments
  33. p75NTR-dependent activation of NF-κB regulates microRNA-503 transcription and pericyte–endothelial crosstalk in diabetes after limb ischaemia
  34. Acetylcholine Suppresses Ventricular Arrhythmias and Improves Conduction and Connexin-43 Properties During Myocardial Ischemia in Isolated Rabbit Hearts
  35. Combined Intramyocardial Delivery of Human Pericytes and Cardiac Stem Cells Additively Improves the Healing of Mouse Infarcted Hearts Through Stimulation of Vascular and Muscular Repair
  36. Migration towards SDF-1 selects angiogenin-expressing bone marrow monocytes endowed with cardiac reparative activity in patients with previous myocardial infarction
  37. Epigenetic Profile of Human Adventitial Progenitor Cells Correlates With Therapeutic Outcomes in a Mouse Model of Limb Ischemia
  38. Challenges in identifying the best source of stem cells for cardiac regeneration therapy
  39. The Role of MicroRNAs in Cardiac Stem Cells
  40. Ex Vivo Molecular Rejuvenation Improves the Therapeutic Activity of Senescent Human Cardiac Stem Cells in a Mouse Model of Myocardial Infarction
  41. Clinical-Grade Human Neural Stem Cells Promote Reparative Neovascularization in Mouse Models of Hindlimb Ischemia
  42. Impaired relaxation despite upregulated calcium-handling protein atrial myocardium from type 2 diabetic patients with preserved ejection fraction
  43. Cardiovascular microRNAs: as modulators and diagnostic biomarkers of diabetic heart disease
  44. Rapid onset of cardiomyopathy in STZ-induced female diabetic mice involves the downregulation of pro-survival Pim-1
  45. Perivascular Delivery of Encapsulated Mesenchymal Stem Cells Improves Postischemic Angiogenesis Via Paracrine Activation of VEGF-A
  46. Pericytes from human veins for treatment of myocardial ischemia
  47. Diabetes Causes Bone Marrow Endothelial Barrier Dysfunction by Activation of the RhoA–Rho-Associated Kinase Signaling Pathway
  48. Boosting the pentose phosphate pathway restores cardiac progenitor cell availability in diabetes
  49. Role for Substance P–Based Nociceptive Signaling in Progenitor Cell Activation and Angiogenesis During Ischemia in Mice and in Human Subjects
  50. Transplantation of Human Pericyte Progenitor Cells Improves the Repair of Infarcted Heart Through Activation of an Angiogenic Program Involving Micro-RNA-132
  51. Intravenous Gene Therapy With PIM-1 Via a Cardiotropic Viral Vector Halts the Progression of Diabetic Cardiomyopathy Through Promotion of Prosurvival Signaling
  52. Tissue Kallikrein Is Essential for Invasive Capacity of Circulating Proangiogenic Cells
  53. Benfotiamine improves functional recovery of the infarcted heart via activation of pro-survival G6PD/Akt signaling pathway and modulation of neurohormonal response
  54. Differential regulation of TNF receptors by vagal nerve stimulation protects heart against acute ischemic injury
  55. Human Adult Vena Saphena Contains Perivascular Progenitor Cells Endowed With Clonogenic and Proangiogenic Potential
  56. Nerve Growth Factor Promotes Cardiac Repair following Myocardial Infarction
  57. Donepezil, an acetylcholinesterase inhibitor against Alzheimer's dementia, promotes angiogenesis in an ischemic hindlimb model
  58. Involvement of Phosphoinositide 3-Kinase γ in Angiogenesis and Healing of Experimental Myocardial Infarction in Mice
  59. Diabetes Mellitus Induces Bone Marrow Microangiopathy
  60. Vitamin B1 Analog Benfotiamine Prevents Diabetes-Induced Diastolic Dysfunction and Heart Failure Through Akt/Pim-1–Mediated Survival Pathway
  61. Engineered Heart Tissue: A Novel Tool to Study the Ischemic Changes of the Heart In Vitro
  62. New device for intraoperative graft assessment: HyperEye charge-coupled device camera system
  63. Anti-Alzheimer's Drug, Donepezil, Markedly Improves Long-Term Survival After Chronic Heart Failure in Mice
  64. Preliminary experience for the evaluation of the intraoperative graft patency with real color charge-coupled device camera system: an advanced device for simultaneous capturing of color and near-infrared images during coronary artery bypass graft☆
  65. Human CD133 + Progenitor Cells Promote the Healing of Diabetic Ischemic Ulcers by Paracrine Stimulation of Angiogenesis and Activation of Wnt Signaling
  66. Critical Role of Tissue Kallikrein in Vessel Formation and Maturation
  67. Chronic intermittent fasting improves the survival following large myocardial ischemia by activation of BDNF/VEGF/PI3K signaling pathway
  68. Vagal nerve stimulation prevents reperfusion injury through inhibition of opening of mitochondrial permeability transition pore independent of the bradycardiac effect
  69. Role of Kinin B 2 Receptor Signaling in the Recruitment of Circulating Progenitor Cells With Neovascularization Potential
  70. Biphasic Elevation of Bilirubin Oxidation During Myocardial Ischemia Reperfusion
  71. Inhibition of Neointimal Hyperplasia Development by MCI-186 is Correlated With Downregulation of Nuclear Factor-κB Pathway
  72. A HIF-1alpha-related gene involved in cell protection from hypoxia by suppression of mitochondrial function
  73. Novel bisindolylmaleimide derivative inhibits mitochondrial permeability transition pore and protects the heart from reperfusion injury
  74. Granulocyte colony-stimulating factor activates Wnt signal to sustain gap junction function through recruitment of β-catenin and cadherin
  75. Bilirubin Oxidation Provoked by Nitric Oxide Radicals Predicts the Progression of Acute Cardiac Allograft Rejection
  76. A Novel Bisindolylmaleimide Derivative Enhances Functional Recovery of Heart After Long-Term Hypothermic Heart Preservation
  77. 5-HT2 receptor blocker sarpogrelate prevents downregulation of antiapoptotic protein Bcl-2 and protects the heart against ischemia–reperfusion injury
  78. Acetylcholine Inhibits the Hypoxia-Induced Reduction of Connexin43 Protein in Rat Cardiomyocytes
  79. Nitric Oxide Stimulates Vascular Endothelial Growth Factor Production in Cardiomyocytes Involved in Angiogenesis
  80. Hydrophilic bile salt ursodeoxycholic acid protects myocardium against reperfusion injury in a PI3K/Akt dependent pathway
  81. Supplementation of Nucleoside-Nucleotide Mixture Enhances Functional Recovery and Energy Metabolism Following Long-Time Hypothermic Heart Preservation
  82. Efferent Vagal Nerve Stimulation Protects Heart Against Ischemia-Induced Arrhythmias by Preserving Connexin43 Protein
  83. Acetylcholine from vagal stimulation protects cardiomyocytes against ischemia and hypoxia involving additive non-hypoxic induction of HIF-1α
  84. Ischemic preconditioning prevents reperfusion heart injury in cardiac hypertrophy by activation of mitochondrial KATP channels
  85. Mitochondrial permeability transition-pore inhibition enhances functional recovery after long-time hypothermic heart preservation
  86. Second window of ischemic preconditioning regulates mitochondrial permeability transition pore by enhancing Bcl-2 expression
  87. Potential role of mitochondrial permeability transition pore following long-time hypothermic heart preservation