All Stories

  1. New palladium complexes with N‐heterocyclic carbene and morpholine ligands: Synthesis, characterization, crystal structure, molecular docking, and biological activities

    Article • Journal of Biochemical and Molecular Toxicology, October 2023, Wiley

    Associate Professor Tugba Taskin Tok

  2. Design, Synthesis, Pharmacological Activities, Structure–Activity Relationship, and In Silico Studies of Novel 5-Substituted-2-(morpholinoimino)-thiazolidin-4-ones

    Article • ACS Omega, October 2023, American Chemical Society (ACS)

    Prof.Dr. emine elçin emre, Associate Professor Tugba Taskin Tok

  3. Deciphering of Biophysical Interaction of Calf Thymus DNA with a Sulfa Drug: Spectroscopic and Molecular Docking Study

    Article • Iranian Journal of Science, September 2023, Springer Science + Business Media

    Associate Professor Tugba Taskin Tok

  4. Thioether-substituted Benzimidazolium Salts: Synthesis, Characterization, Crystal Structure, and Their Inhibitory Properties Against Acetylcholinesterase and Xanthine Oxidase

    Article • Journal of Molecular Structure, September 2023, Elsevier

    Associate Professor Tugba Taskin Tok

  5. Investigation on the Binding properties of a Coumarin Derivative to Insulin by Spectroscopic and Computational Approaches

    Article • Hacettepe Journal of Biology and Chemistry, July 2023, Hacettepe Journal of Biology and Chemistry

    Associate Professor Tugba Taskin Tok

  6. Molecular docking studies and biological activities of benzenesulfonamide-based thiourea and thiazolidinone derivatives targeting cholinesterases, α-glucosidase, and α-amylase enzymes

    Article • Journal of the Turkish Chemical Society Section A Chemistry, May 2023, Journal of the Turkish Chemical Society, Section A: Chemistry

    Associate Professor Tugba Taskin Tok

  7. Design, synthesis, biological evaluation and docking analysis of pyrrolidine-benzenesulfonamides as carbonic anhydrase or acetylcholinesterase inhibitors and antimicrobial agents

    Article • Journal of Biomolecular Structure and Dynamics, May 2023, Taylor & Francis

    Associate Professor Tugba Taskin Tok

  8. Design, Synthesis, Characterization and Biological Activities of Novel S‐(Acyloxy)butyl‐N,N‐Diethyldithiocarbamate Compounds

    Article • ChemistrySelect, May 2023, Wiley

    Associate Professor Tugba Taskin Tok

  9. Chalcones bearing nitrogen‐containing heterocyclics as multi‐targeted inhibitors: Design, synthesis, biological evaluation and molecular docking studies

    Article • Journal of Molecular Recognition, May 2023, Wiley

    Prof.Dr. emine elçin emre, Associate Professor Tugba Taskin Tok

  10. PİRİNÇ KABUK KÜLÜ İLE ENDÜSTRİYEL ATIK SUDAN KADMİYUM İYONUNUN GİDERİLMESİNİN MODELLENMESİNE YÖNELİK BİLGİSAYAR TABANLI BİR YÖNTEM

    Article • Adıyaman Üniversitesi Mühendislik Bilimleri Dergisi, April 2023, Adiyaman University

    Associate Professor Tugba Taskin Tok

  11. Synthesis, Characterization, Bioactivity Impacts of New Anthranilic Acid Hydrazones Containing Aryl Sulfonate Moiety as Fenamate Isosteres

    Article • ChemistrySelect, April 2023, Wiley

    Associate Professor Tugba Taskin Tok

  12. Fluorinated benzimidazolium salts: Synthesis, characterization, molecular docking studies and inhibitory properties against some metabolic enzymes

    Article • Journal of Fluorine Chemistry, April 2023, Elsevier

    Associate Professor Tugba Taskin Tok

  13. DFT, ADMET, molecular docking and molecular dynamics studies of pyridoxal

    Article • Journal of the Indian Chemical Society, March 2023, Elsevier

    Associate Professor Tugba Taskin Tok

  14. HPLC analysis, Phytochemical Content, and Biological Effects of Centaurea kilae Against Some Metabolic Enzymes: In Vitro and In Silico Studies

    Article • ChemistrySelect, February 2023, Wiley

    Associate Professor Tugba Taskin Tok

  15. Synthesis, characterization and inhibitor properties of benzimidazolium salts bearing 4-(methylsulfonyl)benzyl side arms

    Article • Journal of Molecular Structure, February 2023, Elsevier

    Associate Professor Tugba Taskin Tok

  16. In vitroanticancer, antioxidant and enzyme inhibitory potentials of endemicCephalaria elazigensisvar.purpureawithin silicostudies

    Article • Journal of Biomolecular Structure and Dynamics, January 2023, Taylor & Francis

    Associate Professor Tugba Taskin Tok

  17. Design, synthesis, spectroscopic characterizations, single crystal X-ray analysis, in vitro xanthine oxidase and acetylcholinesterase inhibitory evaluation as well as in silico evaluation of selenium-based N-heterocyclic carbene co...

    Article • Journal of Biomolecular Structure and Dynamics, January 2023, Taylor & Francis

    Associate Professor Tugba Taskin Tok

  18. Novel PEPPSI-type N-heterocyclic carbene palladium(II) complexes: Synthesis, characterization, in silico studies and enzyme inhibitory properties against some metabolic enzymes

    Article • Inorganica Chimica Acta, January 2023, Elsevier

    Associate Professor Tugba Taskin Tok

  19. Synthesis, molecular docking and anticancer potential of azolium based salts and their silver complexes: DNA/BSA interaction studies and cell cycle analysis

    Article • Journal of Molecular Liquids, January 2023, Elsevier

    Associate Professor Tugba Taskin Tok

  20. Alzheimer Hastalığında İlacın Yeniden Kullanım İçin Hesaplamalı Yaklaşımlar

    Article • Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi, December 2022, Journal of Natural Sciences

    Associate Professor Tugba Taskin Tok

  21. Acetylphenyl-substituted imidazolium salts: synthesis, characterization, in silico studies and inhibitory properties against some metabolic enzymes

    Article • Molecular Diversity, December 2022, Springer Science + Business Media

    Associate Professor Tugba Taskin Tok

  22. Nimesulide linked acyl thioureas potent carbonic anhydrase I, II and α-glucosidase inhibitors: Design, synthesis and molecular docking studies

    Article • European Journal of Medicinal Chemistry Reports, December 2022, Elsevier

    Associate Professor Tugba Taskin Tok

  23. Novel chiral Schiff base Palladium(II), Nickel(II), Copper(II) and Iron(II) complexes: Synthesis, characterization, anticancer activity and molecular docking studies

    Article • Bioorganic Chemistry, December 2022, Elsevier

    Associate Professor Tugba Taskin Tok

  24. Benzimidazolium Salts Containing Trifluoromethoxybenzyl: Synthesis, Characterization, Crystal Structure, Molecular Docking Studies and Enzymes Inhibitory Properties

    Article • Chemistry & Biodiversity, November 2022, Wiley

    Associate Professor Tugba Taskin Tok

  25. DNA Binding and Anticancer Properties of New Pd(II)-Phosphorus Schiff Base Metal Complexes

    Article • Pharmaceutics, November 2022, MDPI AG

    Associate Professor Tugba Taskin Tok

  26. LC-MS/MS analysis and diverse biological activities of Hypericum scabrum L.: In vitro and in silico research

    Article • South African Journal of Botany, November 2022, Elsevier

    Associate Professor Tugba Taskin Tok

  27. Correction: Sharov et al. Computational Analysis of Molnupiravir. Int. J. Mol. Sci. 2022, 23, 1508

    Article • International Journal of Molecular Sciences, October 2022, MDPI AG

    Associate Professor Tugba Taskin Tok

  28. Synthesis and evaluation of novel xanthene‐based thiazoles as potential antidiabetic agents

    Article • Archiv der Pharmazie, October 2022, Wiley

    Associate Professor Tugba Taskin Tok

  29. Pentafluorobenzyl-substituted benzimidazolium salts: Synthesis, characterization, crystal structures, computational studies and inhibitory properties of some metabolic enzymes

    Article • Journal of Molecular Structure, October 2022, Elsevier

    Associate Professor Tugba Taskin Tok

  30. Phthalimide‐tethered imidazolium salts: Synthesis, characterization, enzyme inhibitory properties, and in silico studies

    Article • Archiv der Pharmazie, September 2022, Wiley

    Associate Professor Tugba Taskin Tok

  31. Derivation of an anti-cancer drug nanocarrier using a malonic acid-based deep eutectic solvent as a functionalization agent

    Article • Journal of Drug Delivery Science and Technology, September 2022, Elsevier

    Associate Professor Tugba Taskin Tok

  32. Turanecio hypochionaeus: Determination of Its Polyphenol Contents, and Bioactivities Potential Assisted with in Silico Studies

    Article • Chemistry & Biodiversity, September 2022, Wiley

    Associate Professor Tugba Taskin Tok

  33. Investigation of the interaction between anticancer drug ibrutinib and double-stranded DNA by electrochemical and molecular docking techniques

    Article • Microchemical Journal, September 2022, Elsevier

    Associate Professor Tugba Taskin Tok

  34. A Biochemical Approach for Hedysarum candidissimum from Turkey: Screening Phytochemicals, Evaluation of Biological Activites, and Molecular Docking Study

    Article • Chemistry & Biodiversity, August 2022, Wiley

    Associate Professor Tugba Taskin Tok

  35. Synthesis, Characterization and Computational Analysis of Thiophene-2,5-Diylbis((3-Mesityl-3-Methylcyclobutyl)Methanone)

    Article • Polycyclic Aromatic Compounds, August 2022, Taylor & Francis

    Associate Professor Tugba Taskin Tok

  36. New PEPPSI‐Pd‐NHC complexes bearing 4‐hydroxyphenylethyl group: Synthesis, characterization, molecular docking, and bioactivity properties

    Article • Archiv der Pharmazie, August 2022, Wiley

    Associate Professor Tugba Taskin Tok

  37. A Novel Fluorescent Probe for the Detection of Cyanide Ions in Solutions and Studies on Its Biophysical Interactions with ctDNA and Proteases

    Article • Journal of Fluorescence, August 2022, Springer Science + Business Media

    Associate Professor Tugba Taskin Tok

  38. Biological activity and molecular docking studies of some N‐phenylsulfonamides against cholinesterases and carbonic anhydrase isoenzymes

    Article • Journal of Molecular Recognition, August 2022, Wiley

    Associate Professor Tugba Taskin Tok

  39. 1-hydroxy-6,6-Dimethyl-3-Phenyl-1,6-Dihydropyridine-2,5-Dione as a Promising Inhibitor of the SARS-CoV-2 Proteins: insight into the Crystal Structure, Hirshfeld Surface Analysis and Computational Study

    Article • Polycyclic Aromatic Compounds, July 2022, Taylor & Francis

    Associate Professor Tugba Taskin Tok

  40. Phytochemical Analysis and Biological Evaluation of Hypericum linarioides Bosse: in Vitro and in Silico Studies

    Article • ChemistrySelect, June 2022, Wiley

    Associate Professor Tugba Taskin Tok

  41. Assessment of antimicrobial and enzymes inhibition effects of Allium kastambulense with in silico studies: Analysis of its phenolic compounds and flavonoid contents

    Article • Arabian Journal of Chemistry, June 2022, Elsevier

    Associate Professor Tugba Taskin Tok

  42. Evaluation of synthetic 2-aryl quinoxaline derivatives as α-amylase, α-glucosidase, acetylcholinesterase, and butyrylcholinesterase inhibitors

    Article • International Journal of Biological Macromolecules, June 2022, Elsevier

    Associate Professor Tugba Taskin Tok

  43. Cytotoxicity effects and biochemical investigation of novel tetrakis-phthalocyanines bearing 2-thiocytosine moieties with molecular docking studies

    Article • Inorganic Chemistry Communications, April 2022, Elsevier

    Associate Professor Tugba Taskin Tok

  44. Spectroscopic and molecular modeling methods to investigate the interaction between psycho-stimulant modafinil and calf thymus DNA using ethidium bromide as a fluorescence probe

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, April 2022, Elsevier

    Associate Professor Tugba Taskin Tok

  45. Structural analysis and calf thymus DNA/HSA binding properties of new carbazole derivative containing piperazine

    Article • Journal of Photochemistry and Photobiology A Chemistry, April 2022, Elsevier

    Associate Professor Tugba Taskin Tok

  46. Synthesis, In silico and in vitro studies of Silver (I)-N heterocyclic carbene complexes

    Article • Journal of Molecular Structure, March 2022, Elsevier

    Associate Professor Tugba Taskin Tok

  47. Benzimidazolium salts bearing the trifluoromethyl group as organofluorine compounds: Synthesis, characterization, crystal structure, in silico study, and inhibitory profiles against acetylcholinesterase and α‐glycosidase

    Article • Journal of Biochemical and Molecular Toxicology, February 2022, Wiley

    Associate Professor Tugba Taskin Tok

  48. Computational Analysis of Molnupiravir

    Article • International Journal of Molecular Sciences, January 2022, MDPI AG

    Associate Professor Tugba Taskin Tok

  49. Discovery of new chiral sulfonamides bearing benzoxadiazole as HIF inhibitors for non-small cell lung cancer therapy: design, microwave-assisted synthesis, binding affinity, in vitro antitumoral activities and in silico studies

    Article • New Journal of Chemistry, January 2022, Royal Society of Chemistry

    Prof.Dr. emine elçin emre, Associate Professor Tugba Taskin Tok

  50. Design of a multi-epitope vaccine against SARS-CoV-2: immunoinformatic and computational methods

    Article • RSC Advances, January 2022, Royal Society of Chemistry

    Associate Professor Tugba Taskin Tok

  51. 1,3‐dipolar cycloaddition reactions of the compound obtaining from cyclopentadiene‐PTAD and biological activities of adducts formed selectively

    Article • Journal of Heterocyclic Chemistry, December 2021, Wiley

    Associate Professor Tugba Taskin Tok

  52. Biology‐oriented drug synthesis and evaluation of secnidazole esters as novel enzyme ınhibitors

    Article • Archiv der Pharmazie, December 2021, Wiley

    Dr. Syed Muhammad Saad, Associate Professor Tugba Taskin Tok

  53. Design, DFT studies, antimicrobial and antioxidant potential of Binuclear N-heterocyclic Carbene (NHCs) complexes, Probing the aspect of DNA interaction through In-vitro and In-silico approach

    Article • Computational Biology and Chemistry, December 2021, Elsevier

    Associate Professor Tugba Taskin Tok

  54. Naphthalene-based bis-N-salicylidene aniline dyes: Crystal structures, Hirshfeld surface analysis, computational study and molecular docking with the SARS-CoV-2 proteins

    Article • Journal of the Iranian Chemical Society, November 2021, Springer Science + Business Media

    Associate Professor Tugba Taskin Tok

  55. Novel tetrakis–phthalocyanines bearing pyrimidine derivative: crystal XRD analysis, enzyme inhibition, molecular docking, and anticancer effects

    Article • Journal of Biomolecular Structure and Dynamics, November 2021, Taylor & Francis

    Associate Professor Tugba Taskin Tok

  56. Pd (II) complexes bearing “SNS” pincer‐type thioether ligands: Application as catalysts in the synthesis of vitamin K 3

    Article • Applied Organometallic Chemistry, October 2021, Wiley

    Associate Professor Tugba Taskin Tok

  57. A study about excellent xanthine oxidase inhibitory effects of new pyridine salts

    Article • Monatshefte für Chemie - Chemical Monthly, August 2021, Springer Science + Business Media

    Associate Professor Tugba Taskin Tok

  58. A detailed understanding of the COL10A1 and SOX9 genes interaction based on potentially damaging mutations in gastric cancer using computational techniques

    Article • Journal of Biomolecular Structure and Dynamics, August 2021, Taylor & Francis

    Associate Professor Tugba Taskin Tok

  59. Silver N‐heterocyclic carbene complexes bearing fluorinated benzyl group: Synthesis, characterization, crystal structure, computational studies, and inhibitory properties against some metabolic enzymes

    Article • Applied Organometallic Chemistry, May 2021, Wiley

    Associate Professor Tugba Taskin Tok

  60. Correction to “Target-Driven Design of a Coumarinyl Chalcone Scaffold Based Novel EF2 Kinase Inhibitor Suppresses Breast Cancer Growth In Vivo”

    Article • ACS Pharmacology & Translational Science, May 2021, American Chemical Society (ACS)

    Prof. Dr. Mehmet AY, Associate Professor Tugba Taskin Tok

  61. Antitumoral effects of Santolina chameacyparissus on Non-Small Cell Lung Cancer Cells

    Article • Journal of Experimental and Clinical Medicine, April 2021, Ondokuzmayis University, Faculty of Medicine

    Associate Professor Tugba Taskin Tok

  62. Target-Driven Design of a Coumarinyl Chalcone Scaffold Based Novel EF2 Kinase Inhibitor Suppresses Breast Cancer Growth In Vivo

    Article • ACS Pharmacology & Translational Science, March 2021, American Chemical Society (ACS)

    Prof. Dr. Mehmet AY, Associate Professor Tugba Taskin Tok

  63. Synthesis, inhibition properties against xanthine oxidase and molecular docking studies of dimethyl N-benzyl-1H-1,2,3-triazole-4,5-dicarboxylate and (N-benzyl-1H-1,2,3-triazole-4,5-diyl)dimethanol derivatives

    Article • Bioorganic Chemistry, March 2021, Elsevier

    Associate Professor Tugba Taskin Tok

  64. Computer-based identification of potential compounds from Salviae miltiorrhizae against Neirisaral adhesion A regulatory protein

    Article • Journal of Biomolecular Structure and Dynamics, December 2020, Taylor & Francis

    Associate Professor Tugba Taskin Tok

  65. Synthesis, anticancer evaluation and in silico ADMET studies on urea/thiourea derivatives from gabapentin

    Article • Phosphorus Sulfur and Silicon and the Related Elements, December 2020, Taylor & Francis

    Associate Professor Tugba Taskin Tok

  66. Polyamidoamine dendrimers: Favorable polymeric nanomaterials for lipase activation

    Article • Materials Today Communications, December 2020, Elsevier

    Associate Professor Tugba Taskin Tok

  67. Combination of QSAR, molecular docking, molecular dynamic simulation and MM-PBSA: analogues of lopinavir and favipiravir as potential drug candidates against COVID-19

    Article • Journal of Biomolecular Structure and Dynamics, November 2020, Taylor & Francis

    Associate Professor Tugba Taskin Tok

  68. Electrochemical, spectroscopic, and molecular docking studies of the interaction between the anti-retroviral drug indinavir and dsDNA

    Article • Journal of Pharmaceutical Analysis, October 2020, Elsevier

    Associate Professor Tugba Taskin Tok

  69. Molecular dynamics simulation, free energy landscape and binding free energy computations in exploration the anti-invasive activity of amygdalin against metastasis

    Article • Computer Methods and Programs in Biomedicine, October 2020, Elsevier

    Associate Professor Tugba Taskin Tok

  70. The (NHC)PdBr2(2-aminopyridine) complexes: synthesis, characterization, molecular docking study, and inhibitor effects on the human serum carbonic anhydrase and serum bovine xanthine oxidase

    Article • Monatshefte für Chemie - Chemical Monthly, October 2020, Springer Science + Business Media

    Associate Professor Tugba Taskin Tok

  71. A selective and molecular imaging approach for anticancer drug: Pemetrexed by nanoparticle accelerated molecularly imprinting polymer

    Article • Electrochimica Acta, September 2020, Elsevier

    Associate Professor Tugba Taskin Tok

  72. Designing heterocyclic chalcones, benzoyl/sulfonyl hydrazones: An insight into their biological activities and molecular docking study

    Article • Journal of Molecular Structure, July 2020, Elsevier

    Prof.Dr. emine elçin emre, Associate Professor Tugba Taskin Tok

  73. SYNTHESIS, ANTIBACTERIAL ACTIVITY AND DOCKING STUDIES OF BENZYL ALCOHOL DERIVATIVES

    Article • Journal of the Turkish Chemical Society Section A Chemistry, June 2020, Journal of the Turkish Chemical Society, Section A: Chemistry

    Associate Professor Tugba Taskin Tok

  74. Bioinformatic and computational analysis for predominant mutations of the Nrf2/Keap1 complex in pediatric leukemia

    Article • Journal of Biomolecular Structure and Dynamics, June 2020, Taylor & Francis

    Associate Professor Tugba Taskin Tok

  75. Using integrated computational approaches to identify safe and rapid treatment for SARS-CoV-2

    Article • Journal of Biomolecular Structure and Dynamics, May 2020, Taylor & Francis

    Associate Professor Tugba Taskin Tok

  76. Amygdalin as multi-target anticancer drug against targets of cell division cycle: double docking and molecular dynamics simulation

    Article • Journal of Biomolecular Structure and Dynamics, March 2020, Taylor & Francis

    Associate Professor Tugba Taskin Tok

  77. Understanding the mechanism of amygdalin’s multifunctional anti-cancer action using computational approach

    Article • Journal of Biomolecular Structure and Dynamics, March 2020, Taylor & Francis

    Associate Professor Tugba Taskin Tok

  78. Synthesis of new morpholine containing 3-amido-9-ethylcarbazole derivative and studies on its biophysical interactions with calf thymus DNA/HSA

    Article • Journal of Biomolecular Structure and Dynamics, March 2020, Taylor & Francis

    Associate Professor Tugba Taskin Tok

  79. Fluorescence chemosensing of meldonium using a cross-reactive sensor array

    Article • The Analyst, January 2020, Royal Society of Chemistry

    Associate Professor Tugba Taskin Tok

  80. Sensitive Nucleic Acid Detection at NH2‐MWCNTs Modified Glassy Carbon Electrode and its Application for Monitoring of Gemcitabine‐DNA Interaction

    Article • Electroanalysis, December 2019, Wiley

    Associate Professor Tugba Taskin Tok

  81. Evaluation of xanthine oxidase inhibitor properties on isoindoline-1,3-dion derivatives and calculation of interaction mechanism

    Article • Journal of Molecular Structure, December 2019, Elsevier

    Associate Professor Tugba Taskin Tok

  82. Prodrugs for nitroreductase-based cancer therapy-3: Antitumor activity of the novel dinitroaniline prodrugs/Ssap-NtrB enzyme suicide gene system: Synthesis, in vitro and in silico evaluation in prostate cancer

    Article • European Journal of Medicinal Chemistry, December 2019, Elsevier

    Associate Professor Tugba Taskin Tok, Prof. Dr. Mehmet AY

  83. A biguanide derivative and its cyclic anologue: Structural chracterization, AChE inhibitory effect and docking studies

    Article • Journal of Molecular Structure, November 2019, Elsevier

    Associate Professor Tugba Taskin Tok

  84. Design, synthesis, biological evaluation and molecular docking of novel moleculesto PARP-1 enzyme

    Article • TURKISH JOURNAL OF CHEMISTRY, October 2019, The Scientific and Technological Research Council of Turkey

    Associate Professor Tugba Taskin Tok

  85. Naproxen Derivative Interaction Properties with ct-DNA

    Article • Hacettepe Journal of Biology and Chemistry, September 2019, Hacettepe Journal of Biology and Chemistry

    Associate Professor Tugba Taskin Tok

  86. Electrochemical Determination and in silico Studies of Fludarabine on NH 2 Functionalized Multiwalled Carbon Nanotube Modified Glassy Carbon Electrode

    Article • Electroanalysis, August 2019, Wiley

    Associate Professor Tugba Taskin Tok

  87. Inhibition of paraoxonase 1 by coumarin‐substituted N‐heterocyclic carbene silver(I), ruthenium(II) and palladium(II) complexes

    Article • Applied Organometallic Chemistry, July 2019, Wiley

    Associate Professor Tugba Taskin Tok

  88. Novel fluorine-containing chiral hydrazide-hydrazones: Design, synthesis, structural elucidation, antioxidant and anticholinesterase activity, and in silico studies

    Article • Chirality, June 2019, Wiley

    Associate Professor Tugba Taskin Tok, Prof.Dr. emine elçin emre

  89. PRODRUGS FOR NITROREDUCTASE BASED CANCER THERAPY- 2: Novel amide/Ntr combinations targeting PC3 cancer cells

    Article • European Journal of Medicinal Chemistry, June 2019, Elsevier

    Associate Professor Tugba Taskin Tok, Prof. Dr. Mehmet AY

  90. Electrochemical, spectroscopic and molecular docking studies on the interaction of calcium channel blockers with dsDNA

    Article • Bioelectrochemistry, June 2019, Elsevier

    Associate Professor Tugba Taskin Tok

  91. Synthesis, Biological Evaluation and Ligand Based Pharmacophore Modeling of New Aromatic Thiosemicarbazones as Potential Anticancer Agents

    Article • Pharmaceutical Chemistry Journal, May 2019, Springer Science + Business Media

    Prof.Dr. emine elçin emre, Associate Professor Tugba Taskin Tok

  92. Structure prediction of eukaryotic elongation factor-2 kinase and identification of the binding mechanisms of its inhibitors: Homology modeling, Molecular Docking and Molecular Dynamics Simulation

    Article • Journal of Biomolecular Structure and Dynamics, March 2019, Taylor & Francis

    Gizem Tatar, Associate Professor Tugba Taskin Tok

  93. The redox mechanism investigation of non-small cell lung cancer drug: Erlotinib via theoretical and experimental techniques and its host–guest detection by β-Cyclodextrin nanoparticles modified glassy carbon electrode

    Article • Sensors and Actuators B Chemical, January 2019, Elsevier

    Associate Professor Tugba Taskin Tok

  94. Multispectroscopic and Computational Investigation of ct-DNA Binding Properties with Hydroxybenzylidene Containing Tetrahydrocarbazole Derivative

    Article • Journal of Fluorescence, October 2018, Springer Science + Business Media

    Associate Professor Tugba Taskin Tok

  95. GR24, a synthetic analog of Strigolactones, alleviates inflammation and promotes Nrf2 cytoprotective response: In vitro and in silico evidences

    Article • Computational Biology and Chemistry, October 2018, Elsevier

    Associate Professor Tugba Taskin Tok

  96. Benzotriazole functionalized N-heterocyclic carbene–silver(I) complexes: Synthesis, cytotoxicity, antimicrobial, DNA binding, and molecular docking studies

    Article • Polyhedron, October 2018, Elsevier

    Associate Professor Tugba Taskin Tok

  97. Xanthine oxidase inhibitory activity of new pyrrole carboxamide derivatives: In vitro and in silico studies

    Article • Archiv der Pharmazie, August 2018, Wiley

    Associate Professor Tugba Taskin Tok

  98. Protonated water-soluble N -heterocyclic carbene ruthenium(II) complexes: Synthesis, cytotoxic and DNA binding properties and molecular docking study

    Article • Journal of Organometallic Chemistry, August 2018, Elsevier

    Associate Professor Tugba Taskin Tok

  99. Determination of potential selective inhibitors for ROCKI and ROCKII isoforms with molecular modeling techniques: Structure Based Docking, ADMET and Molecular Dynamics Simulation

    Article • Journal of Biomolecular Structure and Dynamics, July 2018, Taylor & Francis

    Gizem Tatar, Associate Professor Tugba Taskin Tok

  100. Prodrugs for Nitroreductase Based Cancer Therapy- 1: Metabolite Profile, Cell Cytotoxicity and Molecular Modeling Interactions of Nitro Benzamides with Ssap-NtrB

    Article • Medicinal Chemistry, July 2018, Bentham Science Publishers

    Associate Professor Tugba Taskin Tok, Prof. Dr. Mehmet AY

  101. Synthesis, anticancer activity and ADMET studies of N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-[(3-substituted)ureido/thioureido] benzenesulfonamide derivatives

    Article • Phosphorus Sulfur and Silicon and the Related Elements, March 2018, Taylor & Francis

    Associate Professor Tugba Taskin Tok, Sevda Türk

  102. Investigation of binding properties of two ethidium derivatives with serum albumins: spectral and computational approach

    Article • Journal of Biomolecular Structure and Dynamics, October 2017, Taylor & Francis

    Associate Professor Tugba Taskin Tok

  103. Aryl benzofuran derivatives from the stem bark of Calpocalyx dinklagei attenuate inflammation

    Article • Phytochemistry, September 2017, Elsevier

    Associate Professor Tugba Taskin Tok

  104. Biological evaluation and molecular docking studies of nitro benzamide derivatives with respect to in vitro anti-inflammatory activity

    Article • International Immunopharmacology, February 2017, Elsevier

    Associate Professor Tugba Taskin Tok, Prof. Dr. Mehmet AY

  105. The potential BChE inhibitor

    Article • European Journal of Medicinal Chemistry, November 2016, Elsevier

    Associate Professor Tugba Taskin Tok, Prof.Dr. emine elçin emre

  106. Clarification of Interaction Mechanism of Mouse Hepatitis Virus (MHV) N and nsp3 Protein with Homology Modeling and Protein-Protein Docking Analysis

    Article • Current Computer - Aided Drug Design, July 2016, Bentham Science Publishers

    Associate Professor Tugba Taskin Tok

  107. The new organometalic structure and its properties

    Article • TURKISH JOURNAL OF CHEMISTRY, January 2016, The Scientific and Technological Research Council of Turkey

    Associate Professor Tugba Taskin Tok

  108. The new nonsteroidal anti-inflammatory drug against COX-2

    Article • TURKISH JOURNAL OF CHEMISTRY, January 2015, The Scientific and Technological Research Council of Turkey

    Associate Professor Tugba Taskin Tok

  109. New organometalic compounds and their biological activities

    Article • TURKISH JOURNAL OF CHEMISTRY, January 2015, The Scientific and Technological Research Council of Turkey

    Associate Professor Tugba Taskin Tok

  110. Synthesis, Molecular Modeling, and Biological Evaluation of Novel Chiral Thiosemicarbazone Derivatives as Potent Anticancer Agents

    Article • Chirality, November 2014, Wiley

    Associate Professor Tugba Taskin Tok, Hasan Bayram, Prof.Dr. emine elçin emre

  111. Evaluation of inhibitory effects of benzothiazole and 3-amino-benzothiazolium derivatives on DNA topoisomerase II by molecular modeling studies

    Article • SAR and QSAR in Environmental Research, July 2014, Taylor & Francis

    Associate Professor Tugba Taskin Tok

  112. Anticancer Drug — Friend or Foe

    Article • July 2014, IntechOpen

    Associate Professor Tugba Taskin Tok

  113. Association Between Thr21Met and Ser89Asn Polymorphisms of the Urotensin-II (UTS2) Gene, Diabetes Mellitus, and Diabetic Retinopathy

    Article • Current Eye Research, May 2012, Taylor & Francis

    Associate Professor Tugba Taskin Tok

  114. Insight into eukaryotic topoisomerase II-inhibiting fused heterocyclic compounds in human cancer cell lines by molecular docking

    Article • SAR and QSAR in Environmental Research, April 2012, Taylor & Francis

    Associate Professor Tugba Taskin Tok

  115. QSAR and docking studies of inhibition activity of 5,6-dihydro 11-alkylbenzo[\alpha]carbazole derivatives against estrogen receptor

    Article • TURKISH JOURNAL OF CHEMISTRY, January 2011, The Scientific and Technological Research Council of Turkey (TUBITAK-ULAKBIM) - DIGITAL COMMONS JOURNALS

    Associate Professor Tugba Taskin Tok

  116. QSAR Approach to Correlate TRPV1 Antagonist Activity for a Series of Heteroaromatic Urea

    Article • QSAR & Combinatorial Science, June 2009, Wiley

    Associate Professor Tugba Taskin Tok

  117. Theoretical investigation on chemical and biochemical activities of 5,6-dihydro-11H-benzo[α]carbazole and its derivatives

    Article • Journal of Molecular Structure THEOCHEM, February 2007, Elsevier

    Associate Professor Tugba Taskin Tok