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  1. Identifying highly effective coumarin-based novel cholinesterase inhibitors by in silico and in vitro studies

    Article • Journal of Molecular Graphics and Modelling, September 2022, Elsevier

    Prof. Dr. Mehmet AY

  2. Novel etodolac derivatives as eukaryotic elongation factor 2 kinase (eEF2K) inhibitors for targeted cancer therapy

    Article • RSC Medicinal Chemistry, January 2022, Royal Society of Chemistry

    Prof. Dr. Mehmet AY

  3. Novel inhibitors of eukaryotic elongation factor 2 kinase: In silico, synthesis and in vitro studies

    Article • Bioorganic Chemistry, November 2021, Elsevier

    Prof. Dr. Mehmet AY

  4. New nimesulide derivatives with amide/sulfonamide moieties: Selective COX-2 inhibition and antitumor effects

    Article • European Journal of Medicinal Chemistry, October 2021, Elsevier

    Prof. Dr. Mehmet AY

  5. Prodrugs for Nitroreductase Based Cancer Therapy‐5: Development of Trinitroaniline Prodrugs/Ssap‐NtrB Combinations for Liver Cancer Using Intracellular and Extracellular Conditions

    Article • ChemistrySelect, July 2021, Wiley

    Prof. Dr. Mehmet AY

  6. Correction to “Target-Driven Design of a Coumarinyl Chalcone Scaffold Based Novel EF2 Kinase Inhibitor Suppresses Breast Cancer Growth In Vivo”

    Article • ACS Pharmacology & Translational Science, May 2021, American Chemical Society (ACS)

    Prof. Dr. Mehmet AY, Associate Professor Tugba Taskin Tok

  7. Target-Driven Design of a Coumarinyl Chalcone Scaffold Based Novel EF2 Kinase Inhibitor Suppresses Breast Cancer Growth In Vivo

    Article • ACS Pharmacology & Translational Science, March 2021, American Chemical Society (ACS)

    Prof. Dr. Mehmet AY, Associate Professor Tugba Taskin Tok

  8. Prodrugs for nitroreductase based cancer therapy-4: Towards prostate cancer targeting: Synthesis of N-heterocyclic nitro prodrugs, Ssap-NtrB enzymatic activation and anticancer evaluation

    Article • Bioorganic Chemistry, December 2020, Elsevier

    Prof. Dr. Mehmet AY

  9. A room temperature acetone sensor based on synthesized tetranitro-oxacalix[4]arenes: Thin film fabrication and sensing properties

    Article • Sensors and Actuators A Physical, November 2020, Elsevier

    Prof. Dr. Mehmet AY

  10. Synthesis and biological evaluation of 2,4,6-trinitroaniline derivatives as potent antitumor agents

    Article • Monatshefte für Chemie - Chemical Monthly, October 2020, Springer Science + Business Media

    Prof. Dr. Mehmet AY

  11. Delivery of Small Molecule EF2 Kinase Inhibitor for Breast and Pancreatic Cancer Cells Using Hyaluronic Acid Based Nanogels

    Article • Pharmaceutical Research, March 2020, Springer Science + Business Media

    Prof. Dr. Mehmet AY

  12. Design, Synthesis, and Molecular Modeling Studies of Novel Coumarin Carboxamide Derivatives as eEF-2K Inhibitors

    Article • Journal of Chemical Information and Modeling, February 2020, American Chemical Society (ACS)

    Prof. Dr. Mehmet AY

  13. Prodrugs for nitroreductase-based cancer therapy-3: Antitumor activity of the novel dinitroaniline prodrugs/Ssap-NtrB enzyme suicide gene system: Synthesis, in vitro and in silico evaluation in prostate cancer

    Article • European Journal of Medicinal Chemistry, December 2019, Elsevier

    Associate Professor Tugba Taskin Tok, Prof. Dr. Mehmet AY

  14. In vitro and in silico studies of nitrobenzamide derivatives as potential anti-neuroinflammatory agents

    Article • Journal of Biomolecular Structure and Dynamics, November 2019, Taylor & Francis

    Serdar Durdagi, Prof. Dr. Mehmet AY, Tuğba Tümer , Kader Sahin

  15. Synthesis of SMZ derivatives and investigation of effects on germination, root,and plant growth ofArabidopsis thalianaL.

    Article • TURKISH JOURNAL OF CHEMISTRY, August 2019, The Scientific and Technological Research Council of Turkey (TUBITAK-ULAKBIM) - DIGITAL COMMONS JOURNALS

    Prof. Dr. Mehmet AY

  16. Surface‐modified carbon black derived from used car tires as alternative, reusable, and regenerable catalysts for H 2 release studies from sodium borohydride methanolysis

    Article • International Journal of Energy Research, July 2019, Hindawi Publishing Corporation

    Prof. Dr. Mehmet AY

  17. Abstract 4787: New and potent small molecule as EF2K inhibitor: A novel EF2K inhibitor

    Article • Cancer Research, July 2019, American Association for Cancer Research (AACR)

    Prof. Dr. Mehmet AY

  18. PRODRUGS FOR NITROREDUCTASE BASED CANCER THERAPY- 2: Novel amide/Ntr combinations targeting PC3 cancer cells

    Article • European Journal of Medicinal Chemistry, June 2019, Elsevier

    Associate Professor Tugba Taskin Tok, Prof. Dr. Mehmet AY

  19. Hyaluronic acid and hyaluronic acid: Sucrose nanogels for hydrophobic cancer drug delivery

    Article • International Journal of Biological Macromolecules, April 2019, Elsevier

    Prof. Dr. Mehmet AY

  20. Prodrugs for Nitroreductase Based Cancer Therapy- 1: Metabolite Profile, Cell Cytotoxicity and Molecular Modeling Interactions of Nitro Benzamides with Ssap-NtrB

    Article • Medicinal Chemistry, July 2018, Bentham Science Publishers

    Associate Professor Tugba Taskin Tok, Prof. Dr. Mehmet AY

  21. Electrochemical behavior and voltammetric determination of some nitro-substituted benzamide compounds

    Article • TURKISH JOURNAL OF CHEMISTRY, June 2018, The Scientific and Technological Research Council of Turkey (TUBITAK-ULAKBIM) - DIGITAL COMMONS JOURNALS

    Prof. Dr. Mehmet AY

  22. Biological evaluation and molecular docking studies of nitro benzamide derivatives with respect to in vitro anti-inflammatory activity

    Article • International Immunopharmacology, February 2017, Elsevier

    Associate Professor Tugba Taskin Tok, Prof. Dr. Mehmet AY

  23. Modification of existing antibiotics in the form of precursor prodrugs that can be subsequently activated by nitroreductases of the target pathogen

    Article • Bioorganic & Medicinal Chemistry Letters, August 2016, Elsevier

    Prof. Dr. Mehmet AY

  24. Antiproliferative activity ofHumulus lupulusextracts on human hepatoma (Hep3B), colon (HT-29) cancer cells and proteases, tyrosinase,β-lactamase enzyme inhibition studies

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, September 2015, Taylor & Francis

    Prof. Dr. Mehmet AY

  25. Comparative Study of Antioxidant Properties and Total Phenolic Content of the Extracts of Humulus lupulus L. and Quantification of Bioactive Components by LC–MS/MS and GC–MS

    Article • Journal of Agricultural and Food Chemistry, October 2013, American Chemical Society (ACS)

    Prof. Dr. Mehmet AY

  26. Two New Phenylpropanoid Glycosides from the Leaves and Flowers ofErica arborea

    Article • Helvetica Chimica Acta, January 2010, Wiley

    Prof. Dr. Mehmet AY

  27. Antioxidant phenolic compounds from the leaves ofErica Arborea(Ericaceae)

    Article • Natural Product Research, November 2008, Taylor & Francis

    Prof. Dr. Mehmet AY

  28. Tricetin 4′-O-α-L-rhamnopyranoside: A new flavonoid from the aerial parts of Erica arborea

    Article • Chemistry of Natural Compounds, March 2008, Springer Science + Business Media

    Prof. Dr. Mehmet AY

  29. Antioxidant activity of Erica arborea

    Article • Fitoterapia, December 2007, Elsevier

    Prof. Dr. Mehmet AY

  30. A new flavone from antioxidant extracts of Pistacia terebinthus

    Article • Food Chemistry, January 2007, Elsevier

    Prof. Dr. Mehmet AY

  31. X-ray analysis of sideroxol from Sideritis leptoclada

    Article • Journal of Chemical Crystallography, January 2005, Springer Science + Business Media

    Prof. Dr. Mehmet AY

  32. Highly stereoselective and general synthesis of (z)-3-methyl-2-alken-1-ols via palladium-catalyzed cross coupling of (z)-3-iodo-2-buten-1-ol with organozincs and other organometals

    Article • Tetrahedron Letters, February 1993, Elsevier

    Prof. Dr. Mehmet AY

  33. Selective synthesis of benzene derivatives via palladium-catalyzed cascade carbometallation of alkynes

    Article • Tetrahedron, January 1993, Elsevier

    Prof. Dr. Mehmet AY

  34. Cyclic cascade carbopalladation reactions as a route to benzene and fulvene derivatives

    Article • Tetrahedron Letters, June 1992, Elsevier

    Prof. Dr. Mehmet AY

  35. Electrophilic amination of carbanions

    Article • Chemical Reviews, December 1989, American Chemical Society (ACS)

    Prof. Dr. Mehmet AY

  36. Effect of Copper (I) Iodide and Magnesium Chloride on Amination of Aryl Grignards with Ketoximes

    Article • Synthesis and Reactivity in Inorganic Metal-Organic and Nano-Metal Chemistry, July 1989, Taylor & Francis

    Prof. Dr. Mehmet AY