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  1. Investigation of in vitro anticancer and antioxidant activities of various extracts of Bayramiç Beyazı nectarine, and molecular docking, molecular dynamics simulation, and protein-protein interaction network

    Article • South African Journal of Botany, March 2026, Elsevier

    Prof. Dr. Mehmet AY

  2. Boron Containing Curcumin-Like Compound as an Acetylcholinesterase Inhibitor and Anticancer Agent: Synthesis, Biological Evaluation, and Computational Insights

    Article • Cell Biochemistry and Biophysics, September 2025, Springer Science + Business Media

    Prof. Dr. Mehmet AY

  3. New and potential boron-containing compounds for treatment of Alzheimer's disease and cancers

    Article • Future Medicinal Chemistry, June 2025, Taylor & Francis

    Prof. Dr. Mehmet AY

  4. Synthesis, in silico and bio-evaluation studies of new isothiocyanate derivatives with respect to COX inhibition and H2S release profiles

    Article • RSC Medicinal Chemistry, January 2025, Royal Society of Chemistry

    Prof. Dr. Mehmet AY

  5. Novel benzothiazole/benzothiazole thiazolidine‐2,4‐dione derivatives as potential FOXM1 inhibitors: In silico, synthesis, and in vitro studies

    Article • Archiv der Pharmazie, September 2024, Wiley

    Prof. Dr. Mehmet AY

  6. A drug repurposing study identifies novel FOXM1 inhibitors with in vitro activity against breast cancer cells

    Article • Medical Oncology, June 2024, Springer Science + Business Media

    Prof. Dr. Mehmet AY

  7. Nitro Compounds Inhibit Breast Cancer Cell Proliferation, Migration, and Colony Formation: Molecular Docking, Molecular Dynamics Simulations and Pharmacological Properties

    Article • ChemistrySelect, December 2023, Wiley

    Prof. Dr. Mehmet AY

  8. Synthesis of new imine-/amine-bearing imidazo[1,2-a]pyrimidine derivatives and screening of their cytotoxic activity

    Article • TURKISH JOURNAL OF CHEMISTRY, October 2023, The Scientific and Technological Research Council of Turkey (TUBITAK-ULAKBIM) - DIGITAL COMMONS JOURNALS

    Prof. Dr. Mehmet AY

  9. Major Bioactive Prenylated Flavonoids from Humulus lupulus L., Their Applications in Human Diseases and Structure-Activity Relationships (SAR) – A Review

    Article • Pharmaceutical Sciences, October 2023, MaadRayan Publishing Company

    Prof. Dr. Mehmet AY

  10. Humidity effect on real-time response of tetranitro-oxacalix[4]arene-based surface plasmon resonance (SPR) acetone sensor at room temperature

    Article • Optik, February 2023, Elsevier

    Prof. Dr. Mehmet AY

  11. Identifying highly effective coumarin-based novel cholinesterase inhibitors by in silico and in vitro studies

    Article • Journal of Molecular Graphics and Modelling, September 2022, Elsevier

    Prof. Dr. Mehmet AY

  12. Novel etodolac derivatives as eukaryotic elongation factor 2 kinase (eEF2K) inhibitors for targeted cancer therapy

    Article • RSC Medicinal Chemistry, January 2022, Royal Society of Chemistry

    Prof. Dr. Mehmet AY

  13. Novel inhibitors of eukaryotic elongation factor 2 kinase: In silico, synthesis and in vitro studies

    Article • Bioorganic Chemistry, November 2021, Elsevier

    Prof. Dr. Mehmet AY

  14. New nimesulide derivatives with amide/sulfonamide moieties: Selective COX-2 inhibition and antitumor effects

    Article • European Journal of Medicinal Chemistry, October 2021, Elsevier

    Prof. Dr. Mehmet AY

  15. Prodrugs for Nitroreductase Based Cancer Therapy‐5: Development of Trinitroaniline Prodrugs/Ssap‐NtrB Combinations for Liver Cancer Using Intracellular and Extracellular Conditions

    Article • ChemistrySelect, July 2021, Wiley

    Prof. Dr. Mehmet AY

  16. Correction to “Target-Driven Design of a Coumarinyl Chalcone Scaffold Based Novel EF2 Kinase Inhibitor Suppresses Breast Cancer Growth In Vivo”

    Article • ACS Pharmacology & Translational Science, May 2021, American Chemical Society (ACS)

    Prof. Dr. Mehmet AY, Prof. Dr Tugba Taskin-Tok

  17. Target-Driven Design of a Coumarinyl Chalcone Scaffold Based Novel EF2 Kinase Inhibitor Suppresses Breast Cancer Growth In Vivo

    Article • ACS Pharmacology & Translational Science, March 2021, American Chemical Society (ACS)

    Prof. Dr. Mehmet AY, Prof. Dr Tugba Taskin-Tok

  18. Prodrugs for nitroreductase based cancer therapy-4: Towards prostate cancer targeting: Synthesis of N-heterocyclic nitro prodrugs, Ssap-NtrB enzymatic activation and anticancer evaluation

    Article • Bioorganic Chemistry, December 2020, Elsevier

    Prof. Dr. Mehmet AY

  19. Target-driven design of a coumarinyl chalcone scaffold based novel EF2 Kinase inhibitor suppresses breast cancer growthin vivo

    Article • November 2020, Cold Spring Harbor Laboratory Press

    Prof. Dr. Mehmet AY

  20. A room temperature acetone sensor based on synthesized tetranitro-oxacalix[4]arenes: Thin film fabrication and sensing properties

    Article • Sensors and Actuators A Physical, November 2020, Elsevier

    Prof. Dr. Mehmet AY

  21. Synthesis and biological evaluation of 2,4,6-trinitroaniline derivatives as potent antitumor agents

    Article • Monatshefte für Chemie - Chemical Monthly, October 2020, Springer Science + Business Media

    Prof. Dr. Mehmet AY

  22. Nitroreductases in Prodrug Therapies

    Article • May 2020, Taylor & Francis

    Prof. Dr. Mehmet AY

  23. Delivery of Small Molecule EF2 Kinase Inhibitor for Breast and Pancreatic Cancer Cells Using Hyaluronic Acid Based Nanogels

    Article • Pharmaceutical Research, March 2020, Springer Science + Business Media

    Prof. Dr. Mehmet AY

  24. Design, Synthesis, and Molecular Modeling Studies of Novel Coumarin Carboxamide Derivatives as eEF-2K Inhibitors

    Article • Journal of Chemical Information and Modeling, February 2020, American Chemical Society (ACS)

    Prof. Dr. Mehmet AY

  25. Prodrugs for nitroreductase-based cancer therapy-3: Antitumor activity of the novel dinitroaniline prodrugs/Ssap-NtrB enzyme suicide gene system: Synthesis, in vitro and in silico evaluation in prostate cancer

    Article • European Journal of Medicinal Chemistry, December 2019, Elsevier

    Prof. Dr Tugba Taskin-Tok, Prof. Dr. Mehmet AY

  26. In vitro and in silico studies of nitrobenzamide derivatives as potential anti-neuroinflammatory agents

    Article • Journal of Biomolecular Structure and Dynamics, November 2019, Taylor & Francis

    Serdar Durdagi, Prof. Dr. Mehmet AY, Tuğba Tümer , Kader Sahin

  27. Synthesis of SMZ derivatives and investigation of effects on germination, root,and plant growth ofArabidopsis thalianaL.

    Article • TURKISH JOURNAL OF CHEMISTRY, August 2019, The Scientific and Technological Research Council of Turkey (TUBITAK-ULAKBIM) - DIGITAL COMMONS JOURNALS

    Prof. Dr. Mehmet AY

  28. Surface‐modified carbon black derived from used car tires as alternative, reusable, and regenerable catalysts for H 2 release studies from sodium borohydride methanolysis

    Article • International Journal of Energy Research, July 2019, Hindawi Publishing Corporation

    Prof. Dr. Mehmet AY

  29. Abstract 4787: New and potent small molecule as EF2K inhibitor: A novel EF2K inhibitor

    Article • Cancer Research, July 2019, American Association for Cancer Research (AACR)

    Prof. Dr. Mehmet AY

  30. PRODRUGS FOR NITROREDUCTASE BASED CANCER THERAPY- 2: Novel amide/Ntr combinations targeting PC3 cancer cells

    Article • European Journal of Medicinal Chemistry, June 2019, Elsevier

    Prof. Dr Tugba Taskin-Tok, Prof. Dr. Mehmet AY

  31. Hyaluronic acid and hyaluronic acid: Sucrose nanogels for hydrophobic cancer drug delivery

    Article • International Journal of Biological Macromolecules, April 2019, Elsevier

    Prof. Dr. Mehmet AY

  32. Prodrugs for Nitroreductase Based Cancer Therapy- 1: Metabolite Profile, Cell Cytotoxicity and Molecular Modeling Interactions of Nitro Benzamides with Ssap-NtrB

    Article • Medicinal Chemistry, July 2018, Bentham Science Publishers

    Prof. Dr Tugba Taskin-Tok, Prof. Dr. Mehmet AY

  33. Electrochemical behavior and voltammetric determination of some nitro-substituted benzamide compounds

    Article • TURKISH JOURNAL OF CHEMISTRY, June 2018, The Scientific and Technological Research Council of Turkey (TUBITAK-ULAKBIM) - DIGITAL COMMONS JOURNALS

    Prof. Dr. Mehmet AY

  34. Biological evaluation and molecular docking studies of nitro benzamide derivatives with respect to in vitro anti-inflammatory activity

    Article • International Immunopharmacology, February 2017, Elsevier

    Prof. Dr Tugba Taskin-Tok, Prof. Dr. Mehmet AY

  35. Modification of existing antibiotics in the form of precursor prodrugs that can be subsequently activated by nitroreductases of the target pathogen

    Article • Bioorganic & Medicinal Chemistry Letters, August 2016, Elsevier

    Prof. Dr. Mehmet AY

  36. Antiproliferative activity ofHumulus lupulusextracts on human hepatoma (Hep3B), colon (HT-29) cancer cells and proteases, tyrosinase,β-lactamase enzyme inhibition studies

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, September 2015, Taylor & Francis

    Prof. Dr. Mehmet AY

  37. Comparative Study of Antioxidant Properties and Total Phenolic Content of the Extracts of Humulus lupulus L. and Quantification of Bioactive Components by LC–MS/MS and GC–MS

    Article • Journal of Agricultural and Food Chemistry, October 2013, American Chemical Society (ACS)

    Prof. Dr. Mehmet AY

  38. Two New Phenylpropanoid Glycosides from the Leaves and Flowers ofErica arborea

    Article • Helvetica Chimica Acta, January 2010, Wiley

    Prof. Dr. Mehmet AY

  39. Antioxidant phenolic compounds from the leaves ofErica Arborea(Ericaceae)

    Article • Natural Product Research, November 2008, Taylor & Francis

    Prof. Dr. Mehmet AY

  40. Tricetin 4′-O-α-L-rhamnopyranoside: A new flavonoid from the aerial parts of Erica arborea

    Article • Chemistry of Natural Compounds, March 2008, Springer Science + Business Media

    Prof. Dr. Mehmet AY

  41. Antioxidant activity of Erica arborea

    Article • Fitoterapia, December 2007, Elsevier

    Prof. Dr. Mehmet AY

  42. A new flavone from antioxidant extracts of Pistacia terebinthus

    Article • Food Chemistry, January 2007, Elsevier

    Prof. Dr. Mehmet AY

  43. X-ray analysis of sideroxol from Sideritis leptoclada

    Article • Journal of Chemical Crystallography, January 2005, Springer Science + Business Media

    Prof. Dr. Mehmet AY

  44. Highly stereoselective and general synthesis of (z)-3-methyl-2-alken-1-ols via palladium-catalyzed cross coupling of (z)-3-iodo-2-buten-1-ol with organozincs and other organometals

    Article • Tetrahedron Letters, February 1993, Elsevier

    Prof. Dr. Mehmet AY

  45. Selective synthesis of benzene derivatives via palladium-catalyzed cascade carbometallation of alkynes

    Article • Tetrahedron, January 1993, Elsevier

    Prof. Dr. Mehmet AY

  46. Cyclic cascade carbopalladation reactions as a route to benzene and fulvene derivatives

    Article • Tetrahedron Letters, June 1992, Elsevier

    Prof. Dr. Mehmet AY

  47. Electrophilic amination of carbanions

    Article • Chemical Reviews, December 1989, American Chemical Society (ACS)

    Prof. Dr. Mehmet AY

  48. Effect of Copper (I) Iodide and Magnesium Chloride on Amination of Aryl Grignards with Ketoximes

    Article • Synthesis and Reactivity in Inorganic Metal-Organic and Nano-Metal Chemistry, July 1989, Taylor & Francis

    Prof. Dr. Mehmet AY