Current affiliation: University of QueenslandSubject: Medicine And Medical SciencesPrimary location: Australia
Published in:Current Drug DeliveryPublication date:2004-10-01
This review provides an overview of the immune system with respect to the elicitation of vaccine immune responses at mucosal surfaces, as well as v...
Published in:Current Medicinal ChemistryPublication date:2007-12-01
Published in:Current Medicinal ChemistryPublication date:2008-02-01
An outstanding and highly cited review into the use of lipids to stimulate the immune system to mount immune responses against peptide-based vaccines.
Published in:Current Medicinal ChemistryPublication date:2015-09-30
Endosome entrapment is a key barrier to the success of non-viral gene delivery systems. This review details various methods that have been investig...
Published in:mBioPublication date:2016-06-14
Published in:International Journal of Peptide Research and TherapeuticsPublication date:2016-07-20
Delivery of genetic material to specific tissues, cells, and subcellular localisations is a major issue facing the progress of non-viral gene deliv...
Published in:NanomedicinePublication date:2016-04-01
In this paper we assess the capacity of three fusogenic peptides to promote the endosomal escape of a multicomponent gene delivery system incorpora...
Published in:Chemical SciencePublication date:2016-01-01
Published in:Current Protocols in MicrobiologyPublication date:2015-02-02
Progress in Vaccine Development
This review provides an important introduction to different types of vaccine production technologies, modern techniques for identifying antigens, v...
Published in:Bioorganic & Medicinal ChemistryPublication date:2015-05-01
This article compares the capacity of poly-L-lysine cationic dendrons attached to various cell penetrating peptides (CPPs) to deliver plasmid DNA i...
Published in:Bioorganic & Medicinal Chemistry LettersPublication date:2015-12-01
We developed a non-oncogenic recombinant human papillomavirus type-16 (HPV-16) E7 protein, incorporating the PADRE1024.03 universal T helper epitop...
Published in:Bioconjugate ChemistryPublication date:2014-05-21
This paper provides an efficient means to site-specifically incorporate potent immunostimulatory TLR2 ligands (e.g. Pam2Cys, Pam3Cys and LCP) site-...
Published in:NanomedicinePublication date:2014-01-01
Published in:NanomedicinePublication date:2014-12-01
Published in:International Journal of Organic ChemistryPublication date:2013-01-01
Published in:ChemMedChemPublication date:2013-01-11
Outstanding review of the field of subunit vaccine development. Describes the current state of the art and future directions with a focus on adjuva...
Published in:Nanomedicine Nanotechnology Biology and MedicinePublication date:2013-10-01
This paper provides a simple and efficient means to site-specifically incorporate the synthetic lipid core peptide (LCP) adjuvant into recombinant ...
Published in:Medicinal Research ReviewsPublication date:2009-12-21
Published in:Journal of the American Chemical SocietyPublication date:2010-11-17
ADP-ribosylation is a difficult to study post-translational modification (PTM), with numerous biological roles. We have developed methods that enab...
Published in:Advances in Experimental Medicine and BiologyPublication date:2009-01-01
Published in:Oral Delivery of Macromolecular DrugsPublication date:2009-01-01
Published in:Journal of Medicinal ChemistryPublication date:2008-01-01
Published in:BiopolymersPublication date:2008-01-01
Published in:Journal of Medicinal ChemistryPublication date:2008-03-01
Published in:Journal of Medicinal ChemistryPublication date:2007-09-01
Human papillomavirus type-16 (HPV-16) is responsible for approximately 50 % of cervical cancers. Sequences from the E6 and E7 proteins of this viru...
Published in:Tetrahedron LettersPublication date:2007-07-01
Published in:Journal of Medicinal ChemistryPublication date:2006-10-01
Published in:International Journal of Peptide Research and TherapeuticsPublication date:2006-05-05
Published in:The Journal of Organic ChemistryPublication date:2006-09-01
Published in:Journal of Peptide SciencePublication date:2006-01-01
Published in:Understanding Biology Using PeptidesPublication date:Not available
Published in:ChemInformPublication date:2013-05-13
Published in:International Congress SeriesPublication date:2006-04-01
Published in:Bioorganic & Medicinal ChemistryPublication date:2016-11-01
Targeted drug delivery provides a means to improve efficacy, while reducing side effect and the dose of drug that needs to be delivered. The bombes...
Published in:NanomedicinePublication date:2017-02-01
The delivery of genes or RNA interference (e.g. siRNA) into specific cells, for the expression or knockdown of specific gene products, is essential...
Published in:Biotechnology AdvancesPublication date:2017-03-01
This review describes methods that enable the attachment of immunostimulatory adjuvants onto recombinant protein antigens. The review focuses speci...
Published in:Acta BiomaterialiaPublication date:2017-06-01
The ability to target genes to cancers or to reduce the level of cancer associated genes is a new and exciting means to treat various tumours. In t...
Published in:Bioconjugate ChemistryPublication date:2017-09-11
Methods to attach immunostimulatory adjuvants onto protein vaccine antigens to improve vaccine potency and safety, and to tailor the types of immun...