All Stories

  1. Complete structures of the YenTc holotoxin prepore and pore reveal the evolutionary basis for chitinase incorporation into ABC toxins
  2. Likelihood-based interactive local docking into cryo-EM maps in ChimeraX
  3. Virion morphology and on-virus spike protein structures of diverse SARS-CoV-2 variants
  4. AlphaFold predictions are valuable hypotheses and accelerate but do not replace experimental structure determination
  5. AlphaFold predictions are valuable hypotheses, and accelerate but do not replace experimental structure determination
  6. Accelerating crystal structure determination with iterative AlphaFold prediction
  7. Improved AlphaFold modeling with implicit experimental information
  8. Cryo-EM structures of light-harvesting 2 complexes fromRhodopseudomonas palustrisreveal the molecular origin of absorption tuning
  9. The two-domain elevator-type mechanism of zinc-transporting ZIP proteins
  10. 2.4-Å structure of the double-ring Gemmatimonas phototrophica photosystem
  11. Improved AlphaFold modeling with implicit experimental information
  12. Cryo-EM structure of the dimeric Rhodobacter sphaeroides RC-LH1 core complex at 2.9 Å: the structural basis for dimerisation
  13. Cryo-EM Structure of the Rhodobacter sphaeroides Light-Harvesting 2 Complex at 2.1 Å
  14. Cryo-EM structure of the monomeric Rhodobacter sphaeroides RC–LH1 core complex at 2.5 Å
  15. A structural biology community assessment of AlphaFold 2 applications
  16. Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor
  17. Structures of full-length glycoprotein hormone receptor signalling complexes
  18. Cryo-EM structure of the Rhodospirillum rubrum RC–LH1 complex at 2.5 Å
  19. Structure and ion-release mechanism of PIB-4-type ATPases
  20. Structures of full-length glycoprotein hormone receptor signaling complexes
  21. SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape
  22. MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography
  23. Making the invisible enemy visible
  24. Antibodies to the SARS-CoV-2 receptor-binding domain that maximize breadth and resistance to viral escape
  25. Adaptive Cartesian and torsional restraints for interactive model rebuilding
  26. Molecular basis of ligand recognition and activation of human V2 vasopressin receptor
  27. Structure, Dynamics, Receptor Binding, and Antibody Binding of the Fully Glycosylated Full-Length SARS-CoV-2 Spike Protein in a Viral Membrane
  28. Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity
  29. Improving SARS-CoV-2 structures: Peer review by early coordinate release
  30. Molecular basis of ligand recognition and activation of human V2 vasopressin receptor
  31. Phasertng: directed acyclic graphs for crystallographic phasing
  32. UCSF ChimeraX: Structure visualization for researchers, educators, and developers
  33. Structure, Dynamics, Receptor Binding, and Antibody Binding of Fully-glycosylated Full-length SARS-CoV-2 Spike Protein in a Viral Membrane
  34. Making the invisible enemy visible
  35. Adaptive conformational restraints for interactive model rebuilding in Cartesian and torsion space
  36. Structures of fungal and plant acetohydroxyacid synthases
  37. How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor
  38. Developing a Fully Glycosylated Full-Length SARS-CoV-2 Spike Protein Model in a Viral Membrane
  39. Lig v 1 structure and the inflammatory response to the Ole e 1 protein family
  40. Developing a Fully-glycosylated Full-length SARS-CoV-2 Spike Protein Model in a Viral Membrane
  41. Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab
  42. Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
  43. Evaluation of model refinement in CASP13
  44. Evaluation of template‐based modeling in CASP13
  45. Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin
  46. Molecular basis of cullin-3 (Cul3) ubiquitin ligase subversion by vaccinia virus protein A55
  47. Molecular basis of Cul3 ubiquitin ligase subversion by vaccinia virus protein A55
  48. Bringing macromolecular model building to life with ISOLDE
  49. Xanthine Oxidoreductase: A Novel Therapeutic Target for the Treatment of Chronic Wounds?
  50. Design of Plasmodium vivax Hypoxanthine-Guanine Phosphoribosyltransferase Inhibitors as Potential Antimalarial Therapeutics
  51. Automating tasks in protein structure determination with the clipper python module
  52. Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling
  53. Improved Model of Proton Pump Crystal Structure Obtained by Interactive Molecular Dynamics Flexible Fitting Expands the Mechanistic Model for Proton Translocation in P-Type ATPases
  54. Multiple functional self-association interfaces in plant TIR domains
  55. The CC domain structure from the wheat stem rust resistance protein Sr33 challenges paradigms for dimerization in plant NLR proteins
  56. Re-evaluation of low-resolution crystal structuresviainteractive molecular-dynamics flexible fitting (iMDFF): a case study in complement C4
  57. A structural analysis of DNA binding by hSSB1 (NABP2/OBFC2B) in solution
  58. Prediction of a novel internal rearrangement of the insulin receptor
  59. Antagonists of IGF:Vitronectin Interactions Inhibit IGF-I–Induced Breast Cancer Cell Functions
  60. Higher-Resolution Structure of the Human Insulin Receptor Ectodomain: Multi-Modal Inclusion of the Insert Domain
  61. The rate ofcis–transconformation errors is increasing in low-resolution crystal structures
  62. Lysine residues of IGF-I are substrates for transglutaminases and modulate downstream IGF-I signalling
  63. Vitronectin-Master controller or micromanager?
  64. A pre-clinical functional assessment of an acellular scaffold intended for the treatment of hard-to-heal wounds
  65. Transglutaminases and receptor tyrosine kinases
  66. A peptidomimetic inhibitor of matrix metalloproteinases containing a tetherable linker group
  67. Controlled presentation of recombinant proteins via a zinc-binding peptide-linker in two and three dimensional formats
  68. Nanoscale presentation of cell adhesive molecules via block copolymer self-assembly
  69. Modeling the adhesion of human embryonic stem cells to poly(lactic-co-glycolic acid) surfaces in a 3D environment
  70. Engineering tissue tubes using novel multilayered scaffolds in the rat peritoneal cavity
  71. Analysis of the Phase Behavior of the Aqueous Poly(ethylene glycol)-Ficoll System
  72. Transplantation of 3D scaffolds seeded with human embryonic stem cells: biological features of surrogate tissue and teratoma-forming potential
  73. A Blank Slate? Layer-by-Layer Deposition of Hyaluronic Acid and Chitosan onto Various Surfaces
  74. Systematic selection of solvents for the fabrication of 3D combined macro- and microporous polymeric scaffolds for soft tissue engineering
  75. Modelling oxygen diffusion and cell growth in a porous, vascularising scaffold for soft tissue engineering applications
  76. Scaffolds, Stem Cells, and Tissue Engineering: A Potent Combination!
  77. Controllable Surface Modification of Poly(lactic-co-glycolic acid) (PLGA) by Hydrolysis or Aminolysis I:  Physical, Chemical, and Theoretical Aspects
  78. Quantitative prediction of phase diagrams for polymer partitioning in aqueous two-phase systems