Dr Stephen M Hewitt

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A tumorigenesis threshold for endogenous Myc revealed by dosage-compensation for Myc haploinsufficiency in the absence of p53

Article • July 2025, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
An Open-Source Normothermic Perfusion System Designed for Research Scientists

Article • Journal of Visualized Experiments, July 2025, MyJove Corporation

Dr Stephen M Hewitt
Editor’s Note: mTOR as a Molecular Target in HPV-Associated Oral and Cervical Squamous Carcinomas

Article • Clinical Cancer Research, July 2025, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Elevated tumor NOS2/COX2 promotes immunosuppressive phenotypes associated with poor survival in ER– breast cancer

Article • JCI Insight, July 2025, American Society for Clinical Investigation

Dr Stephen M Hewitt
Clinicopathologic Features, Management, and Outcomes Of Pediatric CRTC1::TRIM11 and MED15::ATF1 Tumors With Spitzoid Morphology: A Case Series

Article • Pediatric Blood & Cancer, May 2025, Wiley

Dr Stephen M Hewitt
Targeting the SARS-CoV-2 reservoir in long COVID

Article • The Lancet Infectious Diseases, May 2025, Elsevier

Dr Stephen M Hewitt
Deconvolution of cell types and states in spatial multiomics utilizing TACIT

Article • Nature Communications, April 2025, Springer Science + Business Media

Dr Stephen M Hewitt
Immunization with peptide encapsulated within synthetic spores activates T cell responses and reduces tumor growth

Article • February 2025, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
DNA methylation patterns are influenced by Pax3::Foxo1 expression and developmental lineage in rhabdomyosarcoma tumours forming in genetically engineered mouse models

Article • The Journal of Pathology, January 2025, Wiley

Dr Stephen M Hewitt
SARS-CoV-2 infection of salivary glands compromises the production of a secreted antifungal peptide with potential implications for development of oral candidiasis

Article • PLoS Pathogens, December 2024, PLOS

Dr Stephen M Hewitt
Analysis of Glomerular Transcriptomes from Nephrotic Patients SuggestAPOL1Risk Variants Impact Parietal Epithelial Cells

Article • November 2024, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
Single-Nucleus RNA Sequencing Reveals Loss of Distal Convoluted Tubule 1 Renal Tubules in HIV Viral Protein R Transgenic Mice

Article • American Journal Of Pathology, October 2024, Elsevier

Dr Stephen M Hewitt
Tumor NOS2 and COX2 Spatial Juxtaposition with CD8+ T Cells Promote Metastatic and Cancer Stem Cell Niches that Lead to Poor Outcome in ER− Breast Cancer

Article • Cancer Research Communications, October 2024, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
A novel pathogenic germline chromosome 3 inversion in von Hippel-Lindau disease

Article • Journal of Medical Genetics, September 2024, BMJ

Dr Stephen M Hewitt
Maternal prolactin or estrogen signaling in hepatocytes does not regulate iron homeostasis during pregnancy

Article • Haematologica, August 2024, Ferrata Storti Foundation (Haematologica)

Dr Stephen M Hewitt
Initiator cell death event induced by SARS-CoV-2 in the human airway epithelium

Article • Science Immunology, July 2024, American Association for the Advancement of Science

Dr Stephen M Hewitt
Contribution of Prediagnostic Host Factors to Shaping the Stromal Microenvironment of Breast Cancer among Sub-Saharan African Women

Article • Cancer Epidemiology Biomarkers & Prevention, July 2024, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Spatial Deconvolution of Cell Types and Cell States at Scale Utilizing TACIT

Article • June 2024, Springer Science + Business Media

Dr Stephen M Hewitt
Characterization of an expanded set of assays for immunomodulatory proteins using targeted mass spectrometry

Article • Scientific Data, June 2024, Springer Science + Business Media

Dr Stephen M Hewitt
Spatial Deconvolution of Cell Types and Cell States at Scale Utilizing TACIT

Article • June 2024, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
Microenvironment shapes small-cell lung cancer neuroendocrine states and presents therapeutic opportunities

Article • Cell Reports Medicine, June 2024, Elsevier

Dr Stephen M Hewitt
Adjuvant COX inhibition augments STING signaling and cytolytic T cell infiltration in irradiated 4T1 tumors

Article • JCI Insight, May 2024, American Society for Clinical Investigation

Dr Stephen M Hewitt
SARS-CoV-2 Infection of Salivary Glands Compromises Oral Antifungal Innate Immunity and Predisposes to Oral Candidiasis

Article • May 2024, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
Single-Cell Transcriptional Signatures of Glomerular Disease in Transgenic Mice with APOL1 Variants

Article • Journal of the American Society of Nephrology, May 2024, Wolters Kluwer Health

Dr Stephen M Hewitt
Growth in children with nephrotic syndrome: a post hoc analysis of the NEPTUNE study

Article • Pediatric Nephrology, April 2024, Springer Science + Business Media

Dr Stephen M Hewitt
ATOH1, TFAP2B, and CEACAM6 as Immunohistochemical Markers to Distinguish Merkel Cell Carcinoma and Small Cell Lung Cancer

Article • Cancers, February 2024, MDPI AG

Dr Stephen M Hewitt
Microenvironment Shapes Small Cell Lung Cancer Neuroendocrine States and Presents Therapeutic Opportunities

Article • February 2024, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
Longitudinal analysis of blood pressure and lipids in childhood nephrotic syndrome

Article • Pediatric Nephrology, February 2024, Springer Science + Business Media

Dr Stephen M Hewitt
Rationale and design of the Nephrotic Syndrome Study Network (NEPTUNE) Match in glomerular diseases: designing the right trial for the right patient, today

Article • Kidney International, February 2024, Elsevier

Dr Stephen M Hewitt
Pediatric contributions and lessons learned from the NEPTUNE cohort study

Article • Pediatric Nephrology, January 2024, Springer Science + Business Media

Dr Stephen M Hewitt
Image‐based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno‐oncology Biomarker Working Group on Breast Cancer

Article • The Journal of Pathology, January 2024, Wiley

Dr Stephen M Hewitt
NOS2 and COX2 Provide Key Spatial Targets that Determine Outcome in ER-Breast Cancer

Article • December 2023, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
Spatial analysis of NOS2 and COX2 interaction with T-effector cells reveals immunosuppressive landscapes associated with poor outcome in ER- breast cancer patients

Article • December 2023, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
Histopathology and SARS-CoV-2 Cellular Localization in Eye Tissues of COVID-19 Autopsies

Article • American Journal Of Pathology, November 2023, Elsevier

Dr Stephen M Hewitt
Quality Assessment of Proteins and RNA Following Storage in Archival Formalin-Fixed Paraffin-Embedded Human Breast Cancer Tissue Microarray Sections

Article • Biopreservation and Biobanking, October 2023, Mary Ann Liebert Inc

Dr Stephen M Hewitt
Spatial proximity of tumor-immune interactions predicts patient outcome in hepatocellular carcinoma

Article • Hepatology, September 2023, Wolters Kluwer Health

Dr Stephen M Hewitt
Pitfalls in machine learning‐based assessment of tumor‐infiltrating lymphocytes in breast cancer: A report of the International Immuno‐Oncology Biomarker Working Group on Breast Cancer

Article • The Journal of Pathology, August 2023, Wiley

Dr Stephen M Hewitt
Spatial analyses of immune cell infiltration in cancer: current methods and future directions: A report of the International Immuno‐Oncology Biomarker Working Group on Breast Cancer

Article • The Journal of Pathology, August 2023, Wiley

Dr Stephen M Hewitt
Pulmonary Co-Infections Detected Premortem Underestimate Postmortem Findings in a COVID-19 Autopsy Case Series

Article • Pathogens, July 2023, MDPI AG

Dr Stephen M Hewitt
Clinical and biological heterogeneity of multisystem inflammatory syndrome in adults following SARS-CoV-2 infection: a case series

Article • Frontiers in Medicine, July 2023, Frontiers

Dr Stephen M Hewitt
Tumor biology and immune infiltration define primary liver cancer subsets linked to overall survival after immunotherapy

Article • Cell Reports Medicine, June 2023, Elsevier

Dr Stephen M Hewitt
Interferon-gamma is quintessential for NOS2 and COX2 expression in ER- breast tumors that lead to poor outcome

Article • Cell Death and Disease, May 2023, Springer Science + Business Media

Dr Stephen M Hewitt
A multiplexed assay for quantifying immunomodulatory proteins supports correlative studies in immunotherapy clinical trials

Article • Frontiers in Oncology, May 2023, Frontiers

Dr Stephen M Hewitt
Associations of breast cancer etiologic factors with stromal microenvironment of primary invasive breast cancers in the Ghana Breast Health Study

Article • April 2023, Research Square

Dr Stephen M Hewitt
The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer

Article • Nature Communications, April 2023, Springer Science + Business Media

Dr Stephen M Hewitt
Interferon-gamma is Quintessential for NOS2 and COX2 Expression in ER-Breast Tumors that Lead to Poor Outcome

Article • April 2023, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
APOL1 kidney risk variants in glomerular diseases modeled in transgenic mice

Article • March 2023, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome

Article • Nature Communications, March 2023, Springer Science + Business Media

Dr Stephen M Hewitt
Scaffolding Protein Connector Enhancer of Kinase Suppressor of Ras 1 (CNKSR1) Regulates MAPK Inhibition Responsiveness in Pancreas Cancer via Crosstalk with AKT Signaling

Article • Molecular Cancer Research, February 2023, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
HIV viral protein R induces loss of DCT1-type renal tubules

Article • February 2023, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
Phase I/II study of PexaVec in combination with immune checkpoint inhibition in refractory metastatic colorectal cancer

Article • Journal for ImmunoTherapy of Cancer, February 2023, BMJ

Dr Stephen M Hewitt
The Application of Guanidinium to Improve Biomolecule Quality in Fixed, Paraffin-embedded Tissue

Article • Journal of Histochemistry & Cytochemistry, February 2023, SAGE Publications

Dr Stephen M Hewitt
Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes

Article • Cancer Discovery, January 2023, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Cell-specific cargo delivery using synthetic bacterial spores

Article • Cell Reports, January 2023, Elsevier

Dr Stephen M Hewitt
Successful lung transplantation using an allograft from a COVID-19–recovered donor: a potential role for subgenomic RNA to guide organ utilization

Article • American Journal of Transplantation, January 2023, Elsevier

Dr Stephen M Hewitt
Pharmacokinetics and tolerability of the dual TORC1/2 inhibitor sapanisertib in combination with the MEK inhibitor trametinib in dogs

Article • Frontiers in Veterinary Science, December 2022, Frontiers

Dr Stephen M Hewitt
SARS-CoV-2 infection and persistence in the human body and brain at autopsy

Article • Nature, December 2022, Springer Science + Business Media

Dr Stephen M Hewitt
Multiregional single-cell dissection of tumor and immune cells reveals stable lock-and-key features in liver cancer

Article • Nature Communications, December 2022, Springer Science + Business Media

Dr Stephen M Hewitt
Prevalence and Mechanisms of Mucus Accumulation in COVID-19 Lung Disease

Article • American Review of Respiratory Disease, December 2022, American Thoracic Society

Dr Stephen M Hewitt
Systemic Nos2 Depletion and Cox inhibition limits TNBC disease progression and alters lymphoid cell spatial orientation and density

Article • Redox Biology, December 2022, Elsevier

Dr Stephen M Hewitt
The role of FXR and TGR5 in reversing and preventing progression of Western diet–induced hepatic steatosis, inflammation, and fibrosis in mice

Article • Journal of Biological Chemistry, November 2022, Elsevier

Dr Stephen M Hewitt
Variant APOL1 protein in plasma associates with larger particles in humans and mouse models of kidney injury

Article • PLOS One, October 2022, PLOS

Dr Stephen M Hewitt
Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome

Article • September 2022, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
HIV-1 Vpr suppresses expression of the thiazide-sensitive sodium chloride co-transporter in the distal convoluted tubule

Article • PLOS One, September 2022, PLOS

Jeffrey Kopp, Dr Stephen M Hewitt
Multicenter analysis of neutrophil extracellular trap dysregulation in adult and pediatric COVID-19

Article • JCI Insight, August 2022, American Society for Clinical Investigation

Dr Stephen M Hewitt
Precocious Puberty in a Boy With Bilateral Leydig Cell Tumors due to a Somatic Gain-of-Function LHCGR Variant

Article • Journal of the Endocrine Society, August 2022, Endocrine Society

Dr Stephen M Hewitt
Protein expression of the gp78 E3 ligase predicts poor breast cancer outcome based on race

Article • JCI Insight, July 2022, American Society for Clinical Investigation

Dr Stephen M Hewitt
Reproducible, high-dimensional imaging in archival human tissue by multiplexed ion beam imaging by time-of-flight (MIBI-TOF)

Article • Laboratory Investigation, July 2022, Elsevier

Dr Stephen M Hewitt
A glomerular transcriptomic landscape of apolipoprotein L1 in Black patients with focal segmental glomerulosclerosis

Article • Kidney International, July 2022, Elsevier

Dr Stephen M Hewitt
NOS2 and COX2 Blockade Limits TNBC Disease Progression and Alters CD8+T Cell Spatial Orientation and Density

Article • June 2022, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
Quantification of Glomerular Structural Lesions: Associations With Clinical Outcomes and Transcriptomic Profiles in Nephrotic Syndrome

Article • American Journal of Kidney Diseases, June 2022, Elsevier

Dr Stephen M Hewitt
Kidney Biopsy Features Most Predictive of Clinical Outcomes in the Spectrum of Minimal Change Disease and Focal Segmental Glomerulosclerosis

Article • Journal of the American Society of Nephrology, May 2022, American Society of Nephrology

Dr Stephen M Hewitt
Locoregional tumor burden and risk of mortality in metastatic breast cancer

Article • npj Precision Oncology, April 2022, Springer Science + Business Media

Dr Stephen M Hewitt
Multicenter analysis of neutrophil extracellular trap dysregulation in adult and pediatric COVID-19

Article • March 2022, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
Single‐cell biology uncovers apoptotic cell death and its spatial organization as a potential modifier of tumor diversity in HCC

Article • Hepatology, February 2022, Wolters Kluwer Health

Dr Stephen M Hewitt
Progesterone receptor isoform ratio dictates antiprogestin/progestin effects on breast cancer growth and metastases: A role for NDRG1

Article • International Journal of Cancer, January 2022, Wiley

Dr Stephen M Hewitt
NOS2 and COX2 Blockade Limits TNBC Disease Progression and Alters CD8 T Cell Spatial Orientation and Density

Article • January 2022, Elsevier

Dr Stephen M Hewitt
Advancing Research on Medical Image Perception by Strengthening Multidisciplinary Collaboration

Article • JNCI Cancer Spectrum, December 2021, Oxford University Press (OUP)

Dr Stephen M Hewitt
Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation

Article • Science Immunology, December 2021, American Association for the Advancement of Science

Dr Stephen M Hewitt
SARS-CoV-2 infection and persistence throughout the human body and brain

Article • December 2021, Springer Science + Business Media

Dr Stephen M Hewitt
Evidence of SARS-CoV-2-Specific T-Cell-Mediated Myocarditis in a MIS-A Case

Article • Frontiers in Immunology, December 2021, Frontiers

Dr Stephen M Hewitt
The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group

Article • npj Breast Cancer, December 2021, Springer Science + Business Media

Khalid El Bairi, Anna Ehinger, Dr Stephen M Hewitt
Spatial mapping of protein composition and tissue organization: a primer for multiplexed antibody-based imaging

Article • Nature Chemical Biology, November 2021, Springer Science + Business Media

Dr Stephen M Hewitt
Targeted Mass Spectrometry Enables Multiplexed Quantification of Immunomodulatory Proteins in Clinical Biospecimens

Article • Frontiers in Immunology, November 2021, Frontiers

Dr Stephen M Hewitt
Mammary collagen architecture and its association with mammographic density and lesion severity among women undergoing image-guided breast biopsy

Article • Breast Cancer Research, November 2021, Springer Science + Business Media

Dr Stephen M Hewitt
Reproducible, high-dimensional imaging in archival human tissue by Multiplexed Ion Beam Imaging by Time-of-Flight (MIBI-TOF)

Article • October 2021, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
Detailed Quantification of Glomerular Structural Lesions Associates with Clinical Outcomes and Transcriptomic Profiles in Nephrotic Syndrome

Article • September 2021, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
Inhibition of mTOR signaling and clinical activity of metformin in oral premalignant lesions

Article • JCI Insight, September 2021, American Society for Clinical Investigation

Dr Stephen M Hewitt
Targeted Mass Spectrometry Enables Quantification of Novel Pharmacodynamic Biomarkers of ATM Kinase Inhibition

Article • Cancers, July 2021, MDPI AG

Dr Stephen M Hewitt
Multiplex Tissue Imaging Harmonization: A Multicenter Experience from CIMAC-CIDC Immuno-Oncology Biomarkers Network

Article • Clinical Cancer Research, July 2021, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer

Article • Nature Communications, June 2021, Springer Science + Business Media

Dr Stephen M Hewitt
CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice

Article • Cell Reports Medicine, June 2021, Elsevier

Dr Stephen M Hewitt
IGF-1 Receptor Signaling Regulates Type II Pneumocyte Senescence and Resulting Macrophage Polarization in Lung Fibrosis

Article • International Journal of Radiation Oncology*Biology*Physics, June 2021, Elsevier

Dr Stephen M Hewitt
Improving data quality in observational research studies: Report of the Cure Glomerulonephropathy (CureGN) network

Article • Contemporary Clinical Trials Communications, June 2021, Elsevier

Dr Stephen M Hewitt
Clinical Significance of Tumor Infiltrating Lymphocytes in Association with Hormone Receptor Expression Patterns in Epithelial Ovarian Cancer

Article • International Journal of Molecular Sciences, May 2021, MDPI AG

Dr Stephen M Hewitt
Crosstalk between WNT and STAT3 is mediated by galectin-3 in tumor progression

Article • Gastric Cancer, April 2021, Springer Science + Business Media

Dr Stephen M Hewitt
Rapidly Progressing Urothelial Carcinoma Due to a Rare TP53 (p.Arg110Pro) Mutation: A Case Report and Review of the Literature

Article • Research and Reports in Urology, April 2021, Taylor & Francis

Dr Stephen M Hewitt
SARS-CoV-2 infection of the oral cavity and saliva

Article • Nature Medicine, March 2021, Springer Science + Business Media

Dr Stephen M Hewitt
Intratumoral γδ T‐Cell Infiltrates, Chemokine (C‐C Motif) Ligand 4/Chemokine (C‐C Motif) Ligand 5 Protein Expression and Survival in Patients With Hepatocellular Carcinoma

Article • Hepatology, March 2021, Wolters Kluwer Health

Dr Stephen M Hewitt
A glomerular transcriptomic landscape of APOL1 in Black patients with focal segmental glomerulosclerosis

Article • February 2021, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
INFORM: INFrared-based ORganizational Measurements of tumor and its microenvironment to predict patient survival

Article • Science Advances, February 2021, American Association for the Advancement of Science

Dr Stephen M Hewitt
Development of CAR T Cells Expressing a Suicide Gene Plus a Chimeric Antigen Receptor Targeting Signaling Lymphocytic-Activation Molecule F7

Article • Molecular Therapy, February 2021, Elsevier

Dr Stephen M Hewitt
Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival

Article • Communications Biology, February 2021, Springer Science + Business Media

Dr Stephen M Hewitt
MEK/ERK signaling is a critical regulator of high-risk human papillomavirus oncogene expression revealing therapeutic targets for HPV-induced tumors

Article • PLoS Pathogens, January 2021, PLOS

Michelle Ozbun, Dr Stephen M Hewitt
Network for Biomarker Immunoprofiling for Cancer Immunotherapy: Cancer Immune Monitoring and Analysis Centers and Cancer Immunologic Data Commons (CIMAC-CIDC)

Article • Clinical Cancer Research, January 2021, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
CRY1Regulates Chemoresistance in Association WithNANOGby Inhibiting Apoptosisvia STAT3Pathway in Patients With Cervical Cancer

Article • Cancer Genomics & Proteomics, January 2021, International Institute of Anticancer Research

Dr Stephen M Hewitt
Development and evaluation of deep learning–based segmentation of histologic structures in the kidney cortex with multiple histologic stains

Article • Kidney International, January 2021, Elsevier

Dr Stephen M Hewitt
Author Correction: PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis

Article • Nature Communications, December 2020, Springer Science + Business Media

Dr Stephen M Hewitt
Tumor-associated macrophage, angiogenesis and lymphangiogenesis markers predict prognosis of non-small cell lung cancer patients

Article • Journal of Translational Medicine, November 2020, Springer Science + Business Media

Dr Stephen M Hewitt
Integrated Single-Cell Atlases Reveal an Oral SARS-CoV-2 Infection and Transmission Axis

Article • October 2020, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
Prognostic implication of SOX2 expression in small intestinal adenocarcinoma

Article • Virchows Archiv, October 2020, Springer Science + Business Media

Dr Stephen M Hewitt
In Utero Severe Acute Respiratory Syndrome Coronavirus 2 Infection

Article • Journal of the Pediatric Infectious Diseases Society, October 2020, Oxford University Press (OUP)

Dr Stephen M Hewitt
Dynamics of genomic and immune responses during primary immunotherapy resistance in mismatch repair–deficient tumors

Article • Molecular Case Studies, October 2020, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt, Dr Howard A Young
The Use of Quantitative Digital Pathology to Measure Proteoglycan and Glycosaminoglycan Expression and Accumulation in Healthy and Diseased Tissues

Article • Journal of Histochemistry & Cytochemistry, September 2020, SAGE Publications

Dr Stephen M Hewitt
Polygenic risk score for the prediction of breast cancer is related to lesser terminal duct lobular unit involution of the breast

Article • npj Breast Cancer, September 2020, Springer Science + Business Media

Dr Stephen M Hewitt
4-HNE Immunohistochemistry and Image Analysis for Detection of Lipid Peroxidation in Human Liver Samples Using Vitamin E Treatment in NAFLD as a Proof of Concept

Article • Journal of Histochemistry & Cytochemistry, September 2020, SAGE Publications

Dr Stephen M Hewitt
Digital pathology and computational image analysis in nephropathology

Article • Nature Reviews Nephrology, August 2020, Springer Science + Business Media

Dr Stephen M Hewitt
Loss of HES-1 Expression Predicts a Poor Prognosis for Small Intestinal Adenocarcinoma Patients

Article • Frontiers in Oncology, August 2020, Frontiers

Dr Stephen M Hewitt
LC3B upregulation by NANOG promotes immune resistance and stem-like property through hyperactivation of EGFR signaling in immune-refractory tumor cells

Article • Autophagy, August 2020, Taylor & Francis

Dr Stephen M Hewitt
Evaluation of the Anti-Tumor Activity of the Humanized Monoclonal Antibody NEO-201 in Preclinical Models of Ovarian Cancer

Article • Frontiers in Oncology, June 2020, Frontiers

Dr Stephen M Hewitt
Persistent Polyfunctional Chimeric Antigen Receptor T Cells That Target Glypican 3 Eliminate Orthotopic Hepatocellular Carcinomas in Mice

Article • Gastroenterology, June 2020, Elsevier

Dr Stephen M Hewitt
Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials

Article • npj Breast Cancer, May 2020, Springer Science + Business Media

Khalid El Bairi, Anna Ehinger, Dr Stephen M Hewitt
Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

Article • npj Breast Cancer, May 2020, Springer Science + Business Media

Khalid El Bairi, Anna Ehinger, Dr Stephen M Hewitt
Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group

Article • npj Breast Cancer, May 2020, Springer Science + Business Media

Khalid El Bairi, Anna Ehinger, Dr Stephen M Hewitt
Low Epstein–Barr Virus Prevalence in Cardia Gastric Cancer Among a High-Incidence Chinese Population

Article • Digestive Diseases and Sciences, May 2020, Springer Science + Business Media

Dr Stephen M Hewitt
Chemoradiotherapy response prediction model by proteomic expressional profiling in patients with locally advanced cervical cancer

Article • Gynecologic Oncology, May 2020, Elsevier

Dr Stephen M Hewitt
Identification of Candidate Genes Associated with Susceptibility to Ovarian Clear Cell Adenocarcinoma Using cis-eQTL Analysis

Article • Journal of Clinical Medicine, April 2020, MDPI AG

Dr Stephen M Hewitt
Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival

Article • Clinical Cancer Research, April 2020, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
The path to a better biomarker: application of a risk management framework for the implementation of PD‐L1 and TILs as immuno‐oncology biomarkers in breast cancer clinical trials and daily practice

Article • The Journal of Pathology, April 2020, Wiley

Anna Ehinger, Khalid El Bairi, Dr Stephen M Hewitt
Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer

Article • Cell Reports Medicine, April 2020, Elsevier

Dr Stephen M Hewitt
Nephrotic Syndrome Disease Activity Predicts Severity of the Associated Hypercoagulopathy

Article • March 2020, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
Reproductive factors and risk of breast cancer by tumor subtypes among Ghanaian women: A population‐based case–control study

Article • International Journal of Cancer, March 2020, Wiley

Dr Stephen M Hewitt
The Challenges of Optimizing Biomarkers to Guide Clinical Decision Making

Article • JNCI Journal of the National Cancer Institute, March 2020, Oxford University Press (OUP)

Dr Stephen M Hewitt
Ultrastructural Characterization of Proteinuric Patients Predicts Clinical Outcomes

Article • Journal of the American Society of Nephrology, February 2020, American Society of Nephrology

Dr Stephen M Hewitt
Diesel exhaust and bladder cancer risk by pathologic stage and grade subtypes

Article • Environment International, February 2020, Elsevier

Dr Stephen M Hewitt
HSP90A inhibition promotes anti-tumor immunity by reversing multi-modal resistance and stem-like property of immune-refractory tumors

Article • Nature Communications, January 2020, Springer Science + Business Media

Dr Stephen M Hewitt
Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis

Article • Nature Communications, January 2020, Springer Science + Business Media

Dr Stephen M Hewitt
CDK7 is a reliable prognostic factor and novel therapeutic target in epithelial ovarian cancer

Article • Gynecologic Oncology, January 2020, Elsevier

Dr Stephen M Hewitt
Using Digital Pathology to Understand Epithelial Characteristics of Benign Breast Disease among Women Undergoing Diagnostic Image-Guided Breast Biopsy

Article • Cancer Prevention Research, December 2019, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Reproductive Factors and Risk of Breast Cancer by Tumor Subtypes among Ghanaian Women: A Population-based Case-control Study

Article • November 2019, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
Application of convolutional neural networks to breast biopsies to delineate tissue correlates of mammographic breast density

Article • npj Breast Cancer, November 2019, Springer Science + Business Media

Dr Stephen M Hewitt
Efficacy and tolerability of anti-programmed death-ligand 1 (PD-L1) antibody (Avelumab) treatment in advanced thymoma

Article • Journal for ImmunoTherapy of Cancer, October 2019, BMJ

Dr Stephen M Hewitt
T-Cell Receptor Gene Therapy for Human Papillomavirus–Associated Epithelial Cancers: A First-in-Human, Phase I/II Study

Article • Journal of Clinical Oncology, October 2019, American Society of Clinical Oncology (ASCO)

Dr Stephen M Hewitt
Fatal encephalopathy with wild‐type JC virus and ruxolitinib therapy

Article • Annals of Neurology, October 2019, Wiley

Dr Stephen M Hewitt
ALDH1A2 Is a Candidate Tumor Suppressor Gene in Ovarian Cancer

Article • Cancers, October 2019, MDPI AG

Dr Stephen M Hewitt
Tumor Cell Biodiversity Drives Microenvironmental Reprogramming in Liver Cancer

Article • Cancer Cell, October 2019, Elsevier

Dr Stephen M Hewitt
Enlightening kidney pathophysiology

Article • Nature Materials, September 2019, Springer Science + Business Media

Dr Stephen M Hewitt
Epigenetic re-wiring of breast cancer by pharmacological targeting of C-terminal binding protein

Article • Cell Death and Disease, September 2019, Springer Science + Business Media

Dr Stephen M Hewitt
Deubiquitylation and stabilization of Notch1 intracellular domain by ubiquitin-specific protease 8 enhance tumorigenesis in breast cancer

Article • Cell Death and Differentiation, September 2019, Springer Science + Business Media

Dr Stephen M Hewitt
No evidence of ongoing HIV replication or compartmentalization in tissues during combination antiretroviral therapy: Implications for HIV eradication

Article • Science Advances, September 2019, American Association for the Advancement of Science

Dr Stephen M Hewitt
A dataset describing a suite of novel antibody reagents for the RAS signaling network

Article • Scientific Data, August 2019, Springer Science + Business Media

Dr Stephen M Hewitt
The longitudinal relationship between patient-reported outcomes and clinical characteristics among patients with focal segmental glomerulosclerosis in the Nephrotic Syndrome Study Network

Article • Clinical Kidney Journal, August 2019, Oxford University Press (OUP)

Dr Stephen M Hewitt
Durvalumab in Combination with Olaparib in Patients with Relapsed SCLC: Results from a Phase II Study

Article • Journal of Thoracic Oncology, August 2019, Elsevier

Dr Stephen M Hewitt, Dr Howard A Young
A Pilot Study of Sirolimus in Subjects with Cowden Syndrome or Other Syndromes Characterized by Germline Mutations in PTEN

Article • The Oncologist, July 2019, Oxford University Press (OUP)

Dr Stephen M Hewitt
Forkhead box protein O1 (FOXO1) and paired box gene 3 (PAX3) overexpression is associated with poor prognosis in patients with cervical cancer

Article • International Journal of Clinical Oncology, July 2019, Springer Science + Business Media

Dr Stephen M Hewitt
Plasma Zonulin Levels in Childhood Nephrotic Syndrome

Article • Frontiers in Pediatrics, May 2019, Frontiers

Dr Stephen M Hewitt
A mouse model of Proteus syndrome

Article • Human Molecular Genetics, May 2019, Oxford University Press (OUP)

Dr Stephen M Hewitt
Health-related quality of life in glomerular disease

Article • Kidney International, May 2019, Elsevier

Sumit Mohan, Gian Marco Ghiggeri, Dorey Glenn, Dr Stephen M Hewitt
Hepatitis B Surface Antigen Activates Unfolded Protein Response in Forming Ground Glass Hepatocytes of Chronic Hepatitis B

Article • Viruses, April 2019, MDPI AG

Dr Stephen M Hewitt
Data, Information, and Knowledge

Article • Journal of Histochemistry & Cytochemistry, March 2019, SAGE Publications

Dr Stephen M Hewitt
An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers

Article • Journal of Clinical Investigation, March 2019, American Society for Clinical Investigation

Dr Stephen M Hewitt
Scale embedding shared neural networks for multiscale histological analysis of prostate cancer

Article • March 2019, SPIE

Dr Stephen M Hewitt
Combination Immunotherapy with IL-4 Pseudomonas Exotoxin and IFN-α and IFN-γ Mediate Antitumor Effects in vitro and in a Mouse Model of Human Ovarian Cancer

Article • Immunotherapy, March 2019, Taylor & Francis

Dr Stephen M Hewitt
APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors

Article • Cell Reports, March 2019, Elsevier

Dr Stephen M Hewitt
Associations of CDH1 germline variant location and cancer phenotype in families with hereditary diffuse gastric cancer (HDGC)

Article • Journal of Medical Genetics, February 2019, BMJ

Dr Stephen M Hewitt
Tofacitinib enhances delivery of antibody-based therapeutics to tumor cells through modulation of inflammatory cells

Article • JCI Insight, February 2019, American Society for Clinical Investigation

Dr Stephen M Hewitt
CureGN Study Rationale, Design, and Methods: Establishing a Large Prospective Observational Study of Glomerular Disease

Article • American Journal of Kidney Diseases, February 2019, Elsevier

Sumit Mohan, Gian Marco Ghiggeri, Dorey Glenn, Dr Stephen M Hewitt
Relationship of DNA methylation to mutational changes and transcriptional organization in fusion‐positive and fusion‐negative rhabdomyosarcoma

Article • International Journal of Cancer, January 2019, Wiley

Dr Stephen M Hewitt
Immunophenotypic Characterization of Canine Splenic Follicular-Derived B-Cell Lymphoma

Article • Veterinary Pathology, January 2019, SAGE Publications

Dr Stephen M Hewitt
Agreement in Histological Assessment of Mitotic Activity Between Microscopy and Digital Whole Slide Images Informs Conversion for Clinical Diagnosis

Article • Academic Pathology, January 2019, SAGE Publications

Dr Stephen M Hewitt
Automated Computational Detection, Quantitation, and Mapping of Mitosis in Whole-Slide Images for Clinically Actionable Surgical Pathology Decision Support

Article • Journal of Pathology Informatics, January 2019, Elsevier

Dr Stephen M Hewitt
Reproductive Factors and Risk of Breast Cancer by Tumour Subtypes Among Ghanaian Women: A Population-Based Case-Control Study

Article • SSRN Electronic Journal, January 2019, Elsevier

Dr Stephen M Hewitt
Correction: Molecular Chaperone HSP90 Is Necessary to Prevent Cellular Senescence via Lysosomal Degradation of p14ARF

Article • Cancer Research, December 2018, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Microvascular inflammation in renal allograft biopsies assessed by endothelial and leukocyte co‐immunostain: a retrospective study on reproducibility and clinical/prognostic correlates

Article • Transplant International, December 2018, Frontiers

Dr Stephen M Hewitt
Clinically Relevant Cytotoxic Immune Cell Signatures and Clonal Expansion of T-Cell Receptors in High-Risk MYCN-Not-Amplified Human Neuroblastoma

Article • Clinical Cancer Research, November 2018, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
APOL1 risk allele RNA contributes to renal toxicity by activating protein kinase R

Article • Communications Biology, November 2018, Springer Science + Business Media

Dr Stephen M Hewitt
Genomic Network-Based Analysis Reveals Pancreatic Adenocarcinoma Up-Regulating Factor-Related Prognostic Markers in Cervical Carcinoma

Article • Frontiers in Oncology, October 2018, Frontiers

Dr Stephen M Hewitt
A transatlantic perspective on the integration of immuno-oncology prognostic and predictive biomarkers in innovative clinical trial design

Article • Seminars in Cancer Biology, October 2018, Elsevier

Dr Stephen M Hewitt
Scoring of tumor-infiltrating lymphocytes: From visual estimation to machine learning

Article • Seminars in Cancer Biology, October 2018, Elsevier

Dr Stephen M Hewitt
Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance

Article • Journal of Clinical Investigation, August 2018, American Society for Clinical Investigation

Dr Stephen M Hewitt
Elevated expression of pancreatic adenocarcinoma upregulated factor (PAUF) is associated with poor prognosis and chemoresistance in epithelial ovarian cancer

Article • Scientific Reports, August 2018, Springer Science + Business Media

Dr Stephen M Hewitt
Increased High Molecular Weight FGF2 in Endocrine-Resistant Breast Cancer

Article • Hormones and Cancer, June 2018, Springer Science + Business Media

Dr Stephen M Hewitt
A multiprotein supercomplex controlling oncogenic signalling in lymphoma

Article • Nature, June 2018, Springer Science + Business Media

Dr Stephen M Hewitt
Targeting Cyclin D-CDK4/6 Sensitizes Immune-Refractory Cancer by Blocking the SCP3–NANOG Axis

Article • Cancer Research, May 2018, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium

Article • Scientific Reports, April 2018, Springer Science + Business Media

Dr Hannah Oh, Dr Stephen M Hewitt
Integrated proteogenomic analysis of metastatic thoracic tumors identifies APOBEC mutagenesis and copy number alterations as drivers of proteogenomic tumor evolution and heterogeneity

Article • April 2018, Cold Spring Harbor Laboratory Press

Dr Stephen M Hewitt
Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors

Article • Annals of the Rheumatic Diseases, April 2018, Elsevier

Dr Stephen M Hewitt
Etiology of hormone receptor positive breast cancer differs by levels of histologic grade and proliferation

Article • International Journal of Cancer, March 2018, Wiley

Dr Stephen M Hewitt
RE: Elevated Bladder Cancer in Northern New England: The Role of Drinking Water and Arsenic

Article • JNCI Journal of the National Cancer Institute, March 2018, Oxford University Press (OUP)

Dr Stephen M Hewitt
Oncogene-induced senescence mediated by c-Myc requires USP10 dependent deubiquitination and stabilization of p14ARF

Article • Cell Death and Differentiation, February 2018, Springer Science + Business Media

Dr Stephen M Hewitt
Reproducibility and Feasibility of Strategies for Morphologic Assessment of Renal Biopsies Using the Nephrotic Syndrome Study Network Digital Pathology Scoring System

Article • Archives of Pathology & Laboratory Medicine, February 2018, Archives of Pathology and Laboratory Medicine

Dr Stephen M Hewitt
The Role of Extracellular Matrix in Innate Immunity, Fugues of Evolution

Article • Journal of Histochemistry & Cytochemistry, February 2018, SAGE Publications

Dr Stephen M Hewitt
APOBEC Mutagenesis and Copy Number Alterations are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors

Article • SSRN Electronic Journal, January 2018, Elsevier

Dr Stephen M Hewitt
Nonalcoholic fatty liver disease in spinal and bulbar muscular atrophy

Article • Neurology, December 2017, Wolters Kluwer Health

Dr Stephen M Hewitt
Histomorphological and Molecular Assessments of the Fixation Times Comparing Formalin and Ethanol-Based Fixatives

Article • Journal of Histochemistry & Cytochemistry, November 2017, SAGE Publications

Dr Stephen M Hewitt
Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors

Article • Advances in Anatomic Pathology, November 2017, Wolters Kluwer Health

Dr Stephen M Hewitt
Societal challenges of precision medicine: Bringing order to chaos

Article • European Journal of Cancer, October 2017, Elsevier

Dr Stephen M Hewitt
Update on tumor-infiltrating lymphocytes (TILs) in breast cancer, including recommendations to assess TILs in residual disease after neoadjuvant therapy and in carcinoma in situ: A report of the International Immuno-Oncology Biomarker Working Group on ...

Article • Seminars in Cancer Biology, October 2017, Elsevier

Dr Stephen M Hewitt
Bcl-2-like Protein 11 (BIM) Expression Is Associated with Favorable Prognosis for Patients with Cervical Cancer

Article • Anticancer Research, September 2017, International Institute of Anticancer Research

Dr Stephen M Hewitt
Assessing Tumor-infiltrating Lymphocytes in Solid Tumors

Article • Advances in Anatomic Pathology, September 2017, Wolters Kluwer Health

Dr Stephen M Hewitt
The anti-cancer effects of itraconazole in epithelial ovarian cancer

Article • Scientific Reports, July 2017, Nature

Dr Stephen M Hewitt
Therapeutically targeting glypican-2 via single-domain antibody-based chimeric antigen receptors and immunotoxins in neuroblastoma

Article • Proceedings of the National Academy of Sciences, July 2017, Proceedings of the National Academy of Sciences

Dr Stephen M Hewitt
Expression of the scaffold connector enhancer of kinase suppressor of Ras 1 (CNKSR1) is correlated with clinical outcome in pancreatic cancer

Article • BMC Cancer, July 2017, Springer Science + Business Media

Dr Stephen M Hewitt
HDAC1 Upregulation by NANOG Promotes Multidrug Resistance and a Stem-like Phenotype in Immune Edited Tumor Cells

Article • Cancer Research, July 2017, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Common Molecular Subtypes Among Asian Hepatocellular Carcinoma and Cholangiocarcinoma

Article • Cancer Cell, July 2017, Elsevier

Dr Stephen M Hewitt
The Impact Factor Is a 20th-Century Relic in an Electronic Journal World of Instant Citation Counts

Article • Journal of Histochemistry & Cytochemistry, June 2017, SAGE Publications

Dr Stephen M Hewitt
Synaptonemal complex protein 3 is associated with lymphangiogenesis in non-small cell lung cancer patients with lymph node metastasis

Article • Journal of Translational Medicine, June 2017, Springer Science + Business Media

Dr Stephen M Hewitt
Discovery and validation of candidate host DNA methylation markers for detection of cervical precancer and cancer

Article • International Journal of Cancer, May 2017, Wiley

Dr Stephen M Hewitt
Multiview boosting digital pathology analysis of prostate cancer

Article • Computer Methods and Programs in Biomedicine, April 2017, Elsevier

Dr Stephen M Hewitt
Formulation and pH of the Buffered Ethanol Fixative BE70

Article • Journal of Histochemistry & Cytochemistry, March 2017, SAGE Publications

Dr Stephen M Hewitt
Editor’s Note

Article • Journal of Histochemistry & Cytochemistry, March 2017, SAGE Publications

Dr Stephen M Hewitt
Computational analysis of the mesenchymal signature landscape in gliomas

Article • BMC Medical Genomics, March 2017, Springer Science + Business Media

Dr Stephen M Hewitt
Progesterone Receptor Isoform Ratio: A Breast Cancer Prognostic and Predictive Factor for Antiprogestin Responsiveness

Article • JNCI Journal of the National Cancer Institute, March 2017, Oxford University Press (OUP)

Dr Stephen M Hewitt
Lumen-based detection of prostate cancer via convolutional neural networks

Article • March 2017, SPIE

Dr Stephen M Hewitt
PAX3-FOXO1 is essential for tumour initiation and maintenance but not recurrence in a human myoblast model of rhabdomyosarcoma

Article • The Journal of Pathology, March 2017, Wiley

Dr Stephen M Hewitt
Interstitial fibrosis scored on whole-slide digital imaging of kidney biopsies is a predictor of outcome in proteinuric glomerulopathies

Article • Nephrology Dialysis Transplantation, February 2017, Oxford University Press (OUP)

Dr Stephen M Hewitt
Digital pathology imaging as a novel platform for standardization and globalization of quantitative nephropathology

Article • Clinical Kidney Journal, February 2017, Oxford University Press (OUP)

Dr Stephen M Hewitt
Relationship between crown-like structures and sex-steroid hormones in breast adipose tissue and serum among postmenopausal breast cancer patients

Article • January 2017, Springer Science + Business Media

Dr Stephen M Hewitt
API5 confers cancer stem cell-like properties through the FGF2-NANOG axis

Article • Oncogenesis, January 2017, Nature

Dr Stephen M Hewitt
Nuclear Architecture Analysis of Prostate Cancer via Convolutional Neural Networks

Article • IEEE Access, January 2017, Institute of Electrical & Electronics Engineers (IEEE)

Dr Stephen M Hewitt
Factors contributing to delays in diagnosis of breast cancers in Ghana, West Africa

Article • Breast Cancer Research and Treatment, December 2016, Springer Science + Business Media

Dr Stephen M Hewitt
Association between breast cancer genetic susceptibility variants and terminal duct lobular unit involution of the breast

Article • International Journal of Cancer, November 2016, Wiley

Dr Stephen M Hewitt, Dr Hannah Oh
Molecular Chaperone HSP90 Is Necessary to Prevent Cellular Senescence via Lysosomal Degradation of p14ARF

Article • Cancer Research, October 2016, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Reduced expression of FILIP1L, a novel WNT pathway inhibitor, is associated with poor survival, progression and chemoresistance in ovarian cancer

Article • Oncotarget, October 2016, Impact Journals, LLC

Dr Stephen M Hewitt
Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups

Article • October 2016, Springer Science + Business Media

Dr Stephen M Hewitt
Relationships between mammographic density, tissue microvessel density, and breast biopsy diagnosis

Article • August 2016, Springer Science + Business Media

Dr Stephen M Hewitt
A melanin-bleaching methodology for molecular and histopathological analysis of formalin-fixed paraffin-embedded tissue

Article • Laboratory Investigation, August 2016, Nature

Dr Stephen M Hewitt
Standardized measures of lobular involution and subsequent breast cancer risk among women with benign breast disease: a nested case–control study

Article • Breast Cancer Research and Treatment, August 2016, Springer Science + Business Media

Dr Stephen M Hewitt
Prognostic significance of annexin A2 and annexin A4 expression in patients with cervical cancer

Article • BMC Cancer, July 2016, Springer Science + Business Media

Dr Stephen M Hewitt
A Buffered Alcohol-Based Fixative for Histomorphologic and Molecular Applications

Article • Journal of Histochemistry & Cytochemistry, July 2016, Journal of Histochemistry & Cytochemistry (The Histochemical Society)

Dr Stephen M Hewitt
Ages at menarche- and menopause-related genetic variants in relation to terminal duct lobular unit involution in normal breast tissue

Article • Breast Cancer Research and Treatment, June 2016, Springer Science + Business Media

Dr Hannah Oh, Dr Stephen M Hewitt
The Application of Digital Pathology to Improve Accuracy in Glomerular Enumeration in Renal Biopsies

Article • PLOS One, June 2016, PLOS

Dr Stephen M Hewitt
Morphometry Predicts Early GFR Change in Primary Proteinuric Glomerulopathies: A Longitudinal Cohort Study Using Generalized Estimating Equations

Article • PLOS One, June 2016, PLOS

Dr Stephen M Hewitt
Automated prostate tissue referencing for cancer detection and diagnosis

Article • BMC Bioinformatics, June 2016, Springer Science + Business Media

Dr Stephen M Hewitt
Expression of fibroblast growth factor receptor family members is associated with prognosis in early stage cervical cancer patients

Article • Journal of Translational Medicine, May 2016, Springer Science + Business Media

Dr Stephen M Hewitt
Relation of Serum Estrogen Metabolites with Terminal Duct Lobular Unit Involution Among Women Undergoing Diagnostic Image-Guided Breast Biopsy

Article • Hormones and Cancer, May 2016, Springer Science + Business Media

Dr Stephen M Hewitt, Dr Hannah Oh
The paraffin-embedded RNA metric (PERM) for RNA isolated from formalin-fixed, paraffin-embedded tissue

Article • BioTechniques, May 2016, Informa UK (Informa Life Sciences)

Dr Stephen M Hewitt
Reproducibility of the NEPTUNE descriptor-based scoring system on whole-slide images and histologic and ultrastructural digital images

Article • Modern Pathology, April 2016, Nature

Dr Anthony Chang, Dr Stephen M Hewitt
Targeting a Cancer-Specific Epitope of the Epidermal Growth Factor Receptor in Triple-Negative Breast Cancer

Article • JNCI Journal of the National Cancer Institute, April 2016, Oxford University Press (OUP)

Dr Stephen M Hewitt
High‐throughput automated scoring of Ki67 in breast cancer tissue microarrays from the Breast Cancer Association Consortium

Article • The Journal of Pathology Clinical Research, April 2016, Wiley

Dr Mustapha Abubakar, Dr Stephen M Hewitt
Reproducibility: It Is Just Good Science

Article • Journal of Histochemistry & Cytochemistry, March 2016, Journal of Histochemistry & Cytochemistry (The Histochemical Society)

Dr Stephen M Hewitt
Circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3 and terminal duct lobular unit involution of the breast: a cross-sectional study of women with benign breast disease

Article • February 2016, Springer Science + Business Media

Dr Stephen M Hewitt
The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl

Article • Breast Cancer Research and Treatment, January 2016, Springer Science + Business Media

Dr Stephen M Hewitt
Time Advances, People and Language Change, but the Fundamentals Remain the Same

Article • Journal of Histochemistry & Cytochemistry, December 2015, Journal of Histochemistry & Cytochemistry (The Histochemical Society)

Dr Stephen M Hewitt
Baseline and early outcomes in glomerular disease patients

Article • Clinical Journal of the American Society of Nephrology, December 2015, American Society of Nephrology

MD richard lafayette, Katherine R Tuttle, Dr Fernando Fervenza, Dr Michelle Hladunewich, Dr Marva Moxey-Mims, Dr Alicia M Neu, Crystal A Gadegbeku, Dr Howard Trachtman, Dr Stephen M Hewitt, Jeffrey Kopp, John Lieske, Professor Peter X.K. Song
Relationship of Terminal Duct Lobular Unit Involution of the Breast with Area and Volume Mammographic Densities

Article • Cancer Prevention Research, December 2015, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt, Dr Hannah Oh
Clinical significance of OCT4 and SOX2 protein expression in cervical cancer

Article • BMC Cancer, December 2015, Springer Science + Business Media

Dr Stephen M Hewitt
Efficacy of Intralesional Botulinum Toxin A for Treatment of Painful Cutaneous Leiomyomas

Article • JAMA Dermatology, October 2015, American Medical Association (AMA)

Dr Stephen M Hewitt
A Novel Quantitative Multiplex Tissue Immunoblotting for Biomarkers Predicts a Prostate Cancer Aggressive Phenotype

Article • Cancer Epidemiology Biomarkers & Prevention, September 2015, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Modification of Occupational Exposures on Bladder Cancer Risk by Common Genetic Polymorphisms

Article • JNCI Journal of the National Cancer Institute, September 2015, Oxford University Press (OUP)

Dr Stephen M Hewitt
PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis

Article • Nature Communications, July 2015, Nature

Dr Stephen M Hewitt
Molecular transitions from papillomavirus infection to cervical precancer and cancer: Role of stromal estrogen receptor signaling

Article • Proceedings of the National Academy of Sciences, June 2015, Proceedings of the National Academy of Sciences

Dr Stephen M Hewitt
Pancreatic adenocarcinoma up-regulated factor expression is associated with disease-specific survival in cervical cancer patients

Article • Human Pathology, June 2015, Elsevier

Dr Stephen M Hewitt
Assessment of a panel of tumor markers for the differential diagnosis of benign and malignant effusions by well-based reverse phase protein array

Article • Diagnostic Pathology, May 2015, Springer Science + Business Media

Dr Stephen M Hewitt
A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis

Article • Nature Genetics, May 2015, Nature

Dr Stephen M Hewitt
Morphology in the Digital Age: Integrating High-Resolution Description of Structural Alterations With Phenotypes and Genotypes

Article • Seminars in Nephrology, May 2015, Elsevier

Dr Stephen M Hewitt
Expression of Stanniocalcin 1 in Thyroid Side Population Cells and Thyroid Cancer Cells

Article • Thyroid, April 2015, Mary Ann Liebert Inc

Dr Stephen M Hewitt
CDK4 Amplification Reduces Sensitivity to CDK4/6 Inhibition in Fusion-Positive Rhabdomyosarcoma

Article • Clinical Cancer Research, March 2015, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Nucleus detection using gradient orientation information and linear least squares regression

Article • March 2015, SPIE

Dr Stephen M Hewitt
Uncertainty in the assessment of immunohistochemical staining with optical and digital microscopy: lessons from a reader study

Article • March 2015, SPIE

Dr Stephen M Hewitt
Risk of follicular lymphoma associated withBCL2translocations in peripheral blood

Article • Leukemia & Lymphoma, March 2015, Taylor & Francis

Dr Stephen M Hewitt
Cross-Disciplinary Biomarkers Research: Lessons Learned by the CKD Biomarkers Consortium

Article • Clinical Journal of the American Society of Nephrology, March 2015, American Society of Nephrology

Dr Stephen M Hewitt, Chi-yuan Hsu, Brad Rovin, PhD Ilse Daehn Daehn
Cell-Cycle Protein Expression in a Population-Based Study of Ovarian and Endometrial Cancers

Article • Frontiers in Oncology, February 2015, Frontiers

Dr Stephen M Hewitt
The Evolution of Pre-analytic Factors in Anatomic Pathology

Article • January 2015, Springer Science + Business Media

Dr Stephen M Hewitt
Proteomic Expressional Profiling of a Paraffin-Embedded Tissue by Multiplex Tissue Immunoblotting

Article • January 2015, Springer Science + Business Media

Dr Stephen M Hewitt
Prognostic Significance of AMP-Dependent Kinase Alpha Expression in Cervical Cancer

Article • Pathobiology, January 2015, Karger Publishers

Dr Stephen M Hewitt
A Well-Based Reverse-Phase Protein Array of Formalin-Fixed Paraffin-Embedded Tissue

Article • January 2015, Springer Science + Business Media

Dr Stephen M Hewitt
Tissue Microarray

Article • January 2015, Springer Science + Business Media

Dr Stephen M Hewitt
Greater absolute risk for all subtypes of breast cancer in the US than Malaysia

Article • Breast Cancer Research and Treatment, December 2014, Springer Science + Business Media

Dr Stephen M Hewitt
Circulating Sex Hormones and Terminal Duct Lobular Unit Involution of the Normal Breast

Article • Cancer Epidemiology Biomarkers & Prevention, December 2014, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Evaluation environment for digital and analog pathology: a platform for validation studies

Article • Journal of Medical Imaging, November 2014, SPIE

Dr Stephen M Hewitt
The 19q12 Bladder Cancer GWAS Signal: Association with Cyclin E Function and Aggressive Disease

Article • Cancer Research, October 2014, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Improving the State of the Science of Immunohistochemistry

Article • Journal of Histochemistry & Cytochemistry, October 2014, Journal of Histochemistry & Cytochemistry (The Histochemical Society)

Dr Stephen M Hewitt
Controls for Immunohistochemistry

Article • Journal of Histochemistry & Cytochemistry, October 2014, Journal of Histochemistry & Cytochemistry (The Histochemical Society)

Dr Stephen M Hewitt
Terminal Duct Lobular Unit Involution of the Normal Breast: Implications for Breast Cancer Etiology

Article • JNCI Journal of the National Cancer Institute, October 2014, Oxford University Press (OUP)

Dr Stephen M Hewitt
microRNA Alterations Driving Acute and Late Stages of Radiation-Induced Fibrosis in a Murine Skin Model

Article • International Journal of Radiation Oncology*Biology*Physics, September 2014, Elsevier

Dr Stephen M Hewitt
Brightfield Proximity Ligation Assay Reveals Both Canonical and Mixed Transforming Growth Factor- /Bone Morphogenetic Protein Smad Signaling Complexes in Tissue Sections

Article • Journal of Histochemistry & Cytochemistry, August 2014, Journal of Histochemistry & Cytochemistry (The Histochemical Society)

Dr Stephen M Hewitt
Consistency and Standardization of Color in Medical Imaging: a Consensus Report

Article • Journal of Digital Imaging, July 2014, Springer Science + Business Media

Dr Stephen M Hewitt
Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome

Article • Journal of Clinical Investigation, July 2014, American Society for Clinical Investigation

Dr Stephen M Hewitt
AR-Regulated TWEAK-FN14 Pathway Promotes Prostate Cancer Bone Metastasis

Article • Cancer Research, June 2014, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Synaptonemal Complex Protein 3 Is a Prognostic Marker in Cervical Cancer

Article • PLOS One, June 2014, PLOS

Dr Stephen M Hewitt
PLCE1 mRNA and Protein Expression and Survival of Patients with Esophageal Squamous Cell Carcinoma and Gastric Adenocarcinoma

Article • Cancer Epidemiology Biomarkers & Prevention, May 2014, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Profiling of Phospho-AKT, Phospho-mTOR, Phospho-MAPK and EGFR in Non-small Cell Lung Cancer

Article • Journal of Histochemistry & Cytochemistry, May 2014, Journal of Histochemistry & Cytochemistry (The Histochemical Society)

Dr Stephen M Hewitt
CLPTM1L Promotes Growth and Enhances Aneuploidy in Pancreatic Cancer Cells

Article • Cancer Research, March 2014, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Profound Prevention of Experimental Brain Metastases of Breast Cancer by Temozolomide in an MGMT-Dependent Manner

Article • Clinical Cancer Research, March 2014, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
eeDAP: An evaluation environment for digital and analog pathology

Article • March 2014, SPIE

Dr Stephen M Hewitt
Expression of stress-induced phosphoprotein1 (STIP1) is associated with tumor progression and poor prognosis in epithelial ovarian cancer

Article • Genes Chromosomes and Cancer, February 2014, Wiley

Dr Stephen M Hewitt
Multiplex Quantitative Measurement of mRNAs From Fixed Tissue Microarray Sections

Article • Applied Immunohistochemistry & Molecular Morphology, January 2014, Wolters Kluwer Health

Professor Elisabeth Smela, Dr Stephen M Hewitt
Observer Performance in the Use of Digital and Optical Microscopy for the Interpretation of Tissue-Based Biomarkers

Article • Analytical Cellular Pathology, January 2014, Hindawi Publishing Corporation

Dr Stephen M Hewitt
MICA/B and ULBP1 NKG2D ligands are independent predictors of good prognosis in cervical cancer

Article • BMC Cancer, January 2014, Springer Science + Business Media

Dr Stephen M Hewitt
HER-2 assessment in formalin-fixed paraffin-embedded breast cancer tissue by well-based reverse phase protein array

Article • Clinical Proteomics, January 2014, Springer Science + Business Media

Dr Stephen M Hewitt
Assessment of vascular endothelial growth factor in formalin fixed, paraffin embedded colon cancer specimens by means of a well-based reverse phase protein array

Article • Proteome Science, January 2014, Springer Science + Business Media

Dr Stephen M Hewitt
Apoptosis inhibitor-5 overexpression is associated with tumor progression and poor prognosis in patients with cervical cancer

Article • BMC Cancer, January 2014, Springer Science + Business Media

Dr Stephen M Hewitt
Multiple chimeric antigen receptors successfully target chondroitin sulfate proteoglycan 4 in several different cancer histologies and cancer stem cells

Article • Journal for ImmunoTherapy of Cancer, January 2014, Springer Science + Business Media

Dr Stephen M Hewitt
Characterization of NADPH oxidase 5 expression in human tumors and tumor cell lines with a novel mouse monoclonal antibody

Article • Free Radical Biology and Medicine, December 2013, Elsevier

Dr Stephen M Hewitt
Breast cancer susceptibility risk associations and heterogeneity by E-cadherin tumor tissue expression

Article • Breast Cancer Research and Treatment, November 2013, Springer Science + Business Media

Dr Stephen M Hewitt
CD44 is prognostic for overall survival in the NCI randomized trial on breast conservation with 25 year follow-up

Article • Breast Cancer Research and Treatment, November 2013, Springer Science + Business Media

Dr Stephen M Hewitt
Sporadic naturally occurring melanoma in dogs as a preclinical model for human melanoma

Article • Pigment Cell & Melanoma Research, November 2013, Wiley

Dr Stephen M Hewitt
Regulation of accumulation and function of myeloid derived suppressor cells in different murine models of hepatocellular carcinoma

Article • Journal of Hepatology, November 2013, Elsevier

Dr Stephen M Hewitt
Application of Selected Reaction Monitoring for Multiplex Quantification of Clinically Validated Biomarkers in Formalin-Fixed, Paraffin-Embedded Tumor Tissue

Article • Journal of Molecular Diagnostics, July 2013, Elsevier

Dr Stephen M Hewitt
Improved survival of gastric cancer with tumour Epstein–Barr virus positivity: an international pooled analysis

Article • Gut, April 2013, BMJ

Dr Stephen M Hewitt, Dr. Roberto Herrera-Goepfert
Synaptonemal complex protein 3 as a novel prognostic marker in early stage non–small cell lung cancer

Article • Human Pathology, April 2013, Elsevier

Professor Junya Fukuoka, Dr Stephen M Hewitt
Design of the Nephrotic Syndrome Study Network (NEPTUNE) to evaluate primary glomerular nephropathy by a multidisciplinary approach

Article • Kidney International, April 2013, Elsevier

Dr Stephen M Hewitt, Crystal A Gadegbeku
Quantitative analysis of TDLUs using adaptive morphological shape techniques

Article • March 2013, SPIE

Dr Stephen M Hewitt
Erratum: Gene expression and epigenetic discovery screen reveal methylation of SFRP2 in prostate cancer

Article • International Journal of Cancer, March 2013, Wiley

Dr Stephen M Hewitt
Follicular Lymphomas in Children and Young Adults

Article • The American Journal of Surgical Pathology, March 2013, Wolters Kluwer Health

Dr Stephen M Hewitt
Functional activity and tumor-specific expression of dual oxidase 2 in pancreatic cancer cells and human malignancies characterized with a novel monoclonal antibody

Article • International Journal of Oncology, February 2013, Spandidos Publications

Dr Stephen M Hewitt
Digital Pathology Evaluation in the Multicenter Nephrotic Syndrome Study Network (NEPTUNE)

Article • Clinical Journal of the American Society of Nephrology, February 2013, American Society of Nephrology

Dr Stephen M Hewitt, Jeffrey Kopp, Sanjeev Sethi
Loss-of-function screen in rhabdomyosarcoma identifies CRKL-YES as a critical signal for tumor growth

Article • Oncogene, January 2013, Nature

Dr Stephen M Hewitt
ORIGINAL ARTICLEExpression Analysis of p16, c-Myc, and mSin3A in Non-small Cell Lung Cancer by Computer Aided Scoring and Analysis (CASA)

Article • Clinical Laboratory, January 2013, Clinical Laboratory Publications

Dr Stephen M Hewitt
The influence of DNA repair on neurological degeneration, cachexia, skin cancer and internal neoplasms: autopsy report of four xeroderma pigmentosum patients (XP-A, XP-C and XP-D)

Article • Acta Neuropathologica Communications, January 2013, Springer Science + Business Media

Dr Stephen M Hewitt
Prognostic assessment of hypoxia and metabolic markers in cervical cancer using automated digital image analysis of immunohistochemistry

Article • Journal of Translational Medicine, January 2013, Springer Science + Business Media

Dr Stephen M Hewitt
Estrogen receptor and progesterone receptor expression in normal terminal duct lobular units surrounding invasive breast cancer

Article • Breast Cancer Research and Treatment, December 2012, Springer Science + Business Media

Dr Stephen M Hewitt
Genetic Variant as a Selection Marker for Anti-Prostate Stem Cell Antigen Immunotherapy of Bladder Cancer

Article • JNCI Journal of the National Cancer Institute, December 2012, Oxford University Press (OUP)

Dr Stephen M Hewitt
Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses

Article • Cancer Research, December 2012, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Nanog signaling in cancer promotes stem-like phenotype and immune evasion

Article • Journal of Clinical Investigation, October 2012, American Society for Clinical Investigation

Dr Stephen M Hewitt
HER3 overexpression is a prognostic indicator of extrahepatic cholangiocarcinoma

Article • Virchows Archiv, October 2012, Springer Science + Business Media

Dr Stephen M Hewitt
A crypticBAP1splice mutation in a family with uveal and cutaneous melanoma, and paraganglioma

Article • Pigment Cell & Melanoma Research, October 2012, Wiley

Dr Stephen M Hewitt
Gene expression and epigenetic discovery screen reveal methylation of SFRP2 in prostate cancer

Article • International Journal of Cancer, September 2012, Wiley

Dr Stephen M Hewitt
What Measures Should Biobankers Employ to Prevent Possible Glitches in Storage Technology?

Article • Biopreservation and Biobanking, August 2012, Mary Ann Liebert Inc

Dr Stephen M Hewitt
Evaluation of Lymphangiogenic Factors, Vascular Endothelial Growth Factor D and E-Cadherin in Distinguishing Inflammatory From Locally Advanced Breast Cancer

Article • Clinical Breast Cancer, August 2012, Elsevier

Dr Stephen M Hewitt
Association of prion protein expression with pancreatic adenocarcinoma survival in the SEER residual tissue repository

Article • Cancer Biomarkers, July 2012, IOS Press

Dr Stephen M Hewitt
Cell-Cycle Control in Urothelial Carcinoma: Large-scale Tissue Array Analysis of Tumor Tissue from Maine and Vermont

Article • Cancer Epidemiology Biomarkers & Prevention, July 2012, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Expression of heme oxygenase-1 in non-small cell lung cancer (NSCLC) and its correlation with clinical data

Article • Lung Cancer, July 2012, Elsevier

Dr Stephen M Hewitt
Genomic copy number alterations in clear cell renal carcinoma: associations with case characteristics and mechanisms of VHL gene inactivation

Article • Oncogenesis, June 2012, Nature

Dr Stephen M Hewitt
A pressure cooking-based DNA extraction from archival formalin-fixed, paraffin-embedded tissue

Article • Analytical Biochemistry, June 2012, Elsevier

Dr Stephen M Hewitt
Human CCR4+CCR6+Th17 Cells Suppress Autologous CD8+ T Cell Responses

Article • The Journal of Immunology, May 2012, The American Association of Immunologists

Dr Stephen M Hewitt
Automatic detection of melanoma progression by histological analysis of secondary sites

Article • Cytometry, March 2012, Wiley

Dr Stephen M Hewitt
Leveling the Playing Field: Bringing Development of Biomarkers and Molecular Diagnostics up to the Standards for Drug Development

Article • Clinical Cancer Research, March 2012, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Impact of Preanalytic Factors on the Design and Application of Integral Biomarkers for Directing Patient Therapy

Article • Clinical Cancer Research, March 2012, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
mTOR as a Molecular Target in HPV-Associated Oral and Cervical Squamous Carcinomas

Article • Clinical Cancer Research, March 2012, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Analysis of Terminal Duct Lobular Unit (TDLU) Involution in Luminal A and Basal Breast Cancers

Article • Breast Cancer Research, January 2012, Springer Science + Business Media

Dr Stephen M Hewitt
Extremely High Tp53 Mutation Load in Esophageal Squamous Cell Carcinoma in Golestan Province, Iran

Article • PLOS One, December 2011, PLOS

Dr Stephen M Hewitt
The cocaine- and amphetamine-regulated transcript mediates ligand-independent activation of ERα, and is an independent prognostic factor in node-negative breast cancer

Article • Oncogene, December 2011, Nature

Dr Stephen M Hewitt
What Are the Most Oppressing Legal and Ethical Issues Facing Biorepositories and What Are Some Strategies to Address Them?

Article • Biopreservation and Biobanking, December 2011, Mary Ann Liebert Inc

Dr Stephen M Hewitt
The role of secreted frizzled-related protein 2 expression in prostate cancer

Article • Histopathology, December 2011, Wiley

Dr Stephen M Hewitt
56. Chemical preservation of tissue: Methods and models

Article • Cryobiology, December 2011, Elsevier

Dr Stephen M Hewitt
Associated expressions of FGFR-2 and FGFR-3: from mouse mammary gland physiology to human breast cancer

Article • Breast Cancer Research and Treatment, November 2011, Springer Science + Business Media

Dr Stephen M Hewitt
Tissue Microarrays as a Tool in the Discovery and Validation of Predictive Biomarkers

Article • October 2011, Springer Science + Business Media

Dr Stephen M Hewitt
Evaluation of eIF4E Expression in an Osteosarcoma-Specific Tissue Microarray

Article • Journal of Pediatric Hematology/Oncology, October 2011, Wolters Kluwer Health

Dr Stephen M Hewitt
Wilms Tumor-1, Claudin-1 and Ezrin Are Useful Immunohistochemical Markers That Help to Distinguish Schwannoma from Fibroblastic Meningioma

Article • Pathology & Oncology Research, September 2011, Springer Science + Business Media

Dr AVNINDER SINGH, Dr Stephen M Hewitt
Paracrine SLPI secretion upregulates MMP-9 transcription and secretion in ovarian cancer cells

Article • Gynecologic Oncology, September 2011, Elsevier

Dr Stephen M Hewitt
Gray zone lymphoma: chromosomal aberrations with immunophenotypic and clinical correlations

Article • Modern Pathology, August 2011, Nature

Dr Stephen M Hewitt
CLSI Releases Updated Guideline for the Development of Immunohistochemical Assays

Article • Applied Immunohistochemistry & Molecular Morphology, July 2011, Wolters Kluwer Health

Dr Stephen M Hewitt
Downregulation of Filamin A Interacting Protein 1-Like is Associated with Promoter Methylation and Induces an Invasive Phenotype in Ovarian Cancer

Article • Molecular Cancer Research, June 2011, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt, Gloria Huang
Phase IIA Trial Testing Erlotinib as an Intervention against Intraductal Pancreatic Mucinous Neoplasms

Article • Cancer Prevention Research, April 2011, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Methylation profiling of mediastinal gray zone lymphoma reveals a distinctive signature with elements shared by classical Hodgkin's lymphoma and primary mediastinal large B-cell lymphoma

Article • Haematologica, March 2011, Ferrata Storti Foundation (Haematologica)

Dr Stephen M Hewitt
Global Gene Expression Profiling and Validation in Esophageal Squamous Cell Carcinoma and Its Association with Clinical Phenotypes

Article • Clinical Cancer Research, March 2011, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers

Article • Journal of Clinical Investigation, March 2011, American Society for Clinical Investigation

Dr Stephen M Hewitt
Factors Influencing the Degradation of Archival Formalin-Fixed Paraffin-Embedded Tissue Sections

Article • Journal of Histochemistry & Cytochemistry, February 2011, SAGE Publications

Dr Stephen M Hewitt
Systematic Proteome Analysis Identifies Transcription Factor YY1 as a Direct Target of miR-34a

Article • Journal of Proteome Research, February 2011, American Chemical Society (ACS)

Dr Stephen M Hewitt
Detection of Somatic Mutations by High-Resolution DNA Melting (HRM) Analysis in Multiple Cancers

Article • PLOS One, January 2011, PLOS

Dr Stephen M Hewitt
Multimodal microscopy for automated histologic analysis of prostate cancer

Article • BMC Cancer, January 2011, Springer Science + Business Media

Dr Stephen M Hewitt
Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma

Article • Journal of Translational Medicine, January 2011, Springer Science + Business Media

Dr Stephen M Hewitt
Loss of Klotho during melanoma progression leads to increased filamin cleavage, increased Wnt5A expression, and enhanced melanoma cell motility

Article • Pigment Cell & Melanoma Research, December 2010, Wiley

Dr Stephen M Hewitt
Modeling metastasis biology and therapy in real time in the mouse lung

Article • Journal of Clinical Investigation, October 2010, American Society for Clinical Investigation

Dr Stephen M Hewitt
Modeling metastasis biology and therapy in real time in the mouse lung

Article • Journal of Clinical Investigation, August 2010, American Society for Clinical Investigation

Dr Stephen M Hewitt
Multiple Endocrine Neoplasia Type 1 Deletion in Pancreatic α-Cells Leads to Development of Insulinomas in Mice

Article • Endocrinology, August 2010, Endocrine Society

Dr Stephen M Hewitt
Immunoguided Laser Assisted Microdissection Techniques for DNA Methylation Analysis of Archival Tissue Specimens

Article • Journal of Molecular Diagnostics, July 2010, Elsevier

Dr Stephen M Hewitt
Polycyclic aromatic hydrocarbon exposure in oesophageal tissue and risk of oesophageal squamous cell carcinoma in north-eastern Iran

Article • Gut, June 2010, BMJ

Dr Stephen M Hewitt
Characterizations and validations of novel antibodies toward translational research

Article • PROTEOMICS - CLINICAL APPLICATIONS, June 2010, Wiley

Dr Stephen M Hewitt
Glucose transporter Glut-1 is detectable in peri-necrotic regions in many human tumor types but not normal tissues: Study using tissue microarrays

Article • Annals of Anatomy - Anatomischer Anzeiger, May 2010, Elsevier

Professor Ali Mobasheri, Dr Stephen M Hewitt
Histo-proteomic profiling of formalin-fixed, paraffin-embedded tissue

Article • Expert Review of Proteomics, April 2010, Taylor & Francis

Dr Stephen M Hewitt
Molecular Pathology in Epidemiologic Studies: A Primer on Key Considerations

Article • Cancer Epidemiology Biomarkers & Prevention, March 2010, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Assessment of Automated Image Analysis of Breast Cancer Tissue Microarrays for Epidemiologic Studies

Article • Cancer Epidemiology Biomarkers & Prevention, March 2010, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt, Sean Davis
Microscopic resolution imaging and proteomics correlation at histogeographically identical location: point by point correlation between ex vivo tissue imaging with high field MRI and multiplex tissue immunoblotting for proteomics profiling

Article • March 2010, SPIE

Dr Stephen M Hewitt
Analysis of the expression of human tumor antigens in ovarian cancer tissues

Article • Cancer Biomarkers, February 2010, IOS Press

Dr Stephen M Hewitt
Global Genomic and Proteomic Analysis Identifies Biological Pathways Related to High-Risk Neuroblastoma

Article • Journal of Proteome Research, January 2010, American Chemical Society (ACS)

Dr Stephen M Hewitt
Overexpression of Phospho-eIF4E Is Associated with Survival through AKT Pathway in Non-Small Cell Lung Cancer

Article • Clinical Cancer Research, December 2009, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
NRG1 / ERBB3 signaling in melanocyte development and melanoma: inhibition of differentiation and promotion of proliferation

Article • Pigment Cell & Melanoma Research, December 2009, Wiley

Dr Stephen M Hewitt
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma

Article • Oncogene, October 2009, Nature

Dr Stephen M Hewitt
Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models

Article • Journal of Clinical Investigation, October 2009, American Society for Clinical Investigation

Dr Stephen M Hewitt
Cytokeratin Immunoexpression in Esophageal Squamous Cell Carcinoma of High-risk Population in Northeast India

Article • Applied Immunohistochemistry & Molecular Morphology, October 2009, Wolters Kluwer Health

Dr AVNINDER SINGH, Dr Stephen M Hewitt
The Chemokine CXCL16 and Its Receptor, CXCR6, as Markers and Promoters of Inflammation-Associated Cancers

Article • PLOS One, August 2009, PLOS

Dr Stephen M Hewitt
Correlation between clinical outcome and growth factor pathway expression in osteogenic sarcoma

Article • Cancer, August 2009, Wiley

Dr Stephen M Hewitt
Automated Quantitative Assessment of HER-2/neu Immunohistochemical Expression in Breast Cancer

Article • IEEE Transactions on Medical Imaging, June 2009, Institute of Electrical & Electronics Engineers (IEEE)

Dr Stephen M Hewitt
DEAR1 Is a Dominant Regulator of Acinar Morphogenesis and an Independent Predictor of Local Recurrence-Free Survival in Early-Onset Breast Cancer

Article • PLoS Medicine, May 2009, PLOS

Dr Stephen M Hewitt, Khandan Keyomarsi
Molecular profiling to identify molecular mechanism in esophageal cancer with familial clustering

Article • Oncology Reports, April 2009, Spandidos Publications

Dr Stephen M Hewitt
Deciphering von Hippel-Lindau (VHL/Vhl)-Associated Pancreatic Manifestations by Inactivating Vhl in Specific Pancreatic Cell Populations

Article • PLOS One, April 2009, PLOS

Dr Stephen M Hewitt
Associations between Selected Biomarkers and Prognosis in a Population-Based Pancreatic Cancer Tissue Microarray

Article • Cancer Research, March 2009, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Sperm-Derived SPANX-B Is a Clinically Relevant Tumor Antigen That Is Expressed in Human Tumors and Readily Recognized by Human CD4+ and CD8+ T Cells

Article • Clinical Cancer Research, March 2009, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Recapitulation of Pancreatic Neuroendocrine Tumors in Human Multiple Endocrine Neoplasia Type I Syndrome via Pdx1-Directed Inactivation of Men1

Article • Cancer Research, February 2009, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
The Expression of Phospho-AKT, Phospho-mTOR, and PTEN in Extrahepatic Cholangiocarcinoma

Article • Clinical Cancer Research, January 2009, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Transfer and Multiplex Immunoblotting of a Paraffin Embedded Tissue

Article • January 2009, Springer Science + Business Media

Dr Stephen M Hewitt
Tissue Microarrays as a Tool in the Discovery and Validation of Tumor Markers

Article • January 2009, Springer Science + Business Media

Dr Stephen M Hewitt
Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression

Article • BMC Genomics, January 2009, Springer Science + Business Media

Dr Stephen M Hewitt, Sean Davis
Biomarkers of apoptosis and survival in esophageal squamous cell carcinoma

Article • BMC Cancer, January 2009, Springer Science + Business Media

Dr Stephen M Hewitt
Tumor vasculature-targeted delivery of tumor necrosis factor-α*

Article • Cancer, December 2008, Wiley

Dr Stephen M Hewitt
DNA Methylation Represses IFN- -Induced and Signal Transducer and Activator of Transcription 1-Mediated IFN Regulatory Factor 8 Activation in Colon Carcinoma Cells

Article • Molecular Cancer Research, December 2008, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Wnt5A Regulates Expression of Tumor-Associated Antigens in Melanoma via Changes in Signal Transducers and Activators of Transcription 3 Phosphorylation

Article • Cancer Research, December 2008, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
The actin-cytoskeleton linker protein ezrin is regulated during osteosarcoma metastasis by PKC

Article • Oncogene, December 2008, Nature

Dr Stephen M Hewitt
Global Histone H4 Acetylation and HDAC2 Expression in Colon Adenoma and Carcinoma

Article • Digestive Diseases and Sciences, December 2008, Springer Science + Business Media

Dr Seyed Mehdi Nouraie, Dr Stephen M Hewitt
H. pylori-Induced Apoptosis in Human Gastric Cancer Cells Mediated via the Release of Apoptosis-Inducing Factor from Mitochondria

Article • Helicobacter, December 2008, Wiley

Dr Seyed Mehdi Nouraie, Dr Stephen M Hewitt
Consensus Recommendations on Estrogen Receptor Testing in Breast Cancer By Immunohistochemistry

Article • Applied Immunohistochemistry & Molecular Morphology, December 2008, Wolters Kluwer Health

Dr Stephen M Hewitt
Recommendations for Collection and Handling of Specimens From Group Breast Cancer Clinical Trials

Article • Journal of Clinical Oncology, October 2008, American Society of Clinical Oncology (ASCO)

Dr Stephen M Hewitt
Validation of proteomic-based discovery with tissue microarrays

Article • PROTEOMICS - CLINICAL APPLICATIONS, October 2008, Wiley

Dr Stephen M Hewitt
A well-based reverse-phase protein array applicable to extracts from formalin-fixed paraffin-embedded tissue

Article • PROTEOMICS - CLINICAL APPLICATIONS, October 2008, Wiley

Dr Stephen M Hewitt
Functional Characterization of Filamin A Interacting Protein 1-Like, a Novel Candidate for Antivascular Cancer Therapy

Article • Cancer Research, September 2008, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Pharmacodynamic Assessment of Histone Deacetylase Inhibitors: Infrared Vibrational Spectroscopic Imaging of Protein Acetylation

Article • Analytical Chemistry, August 2008, American Chemical Society (ACS)

Dr Stephen M Hewitt
Expression of the Interferon Regulatory Factor 8/ICSBP-1 in Human Reactive Lymphoid Tissues and B-cell Lymphomas: A Novel Germinal Center Marker

Article • The American Journal of Surgical Pathology, August 2008, Wolters Kluwer Health

Dr Stephen M Hewitt
Factors in Tissue Handling and Processing That Impact RNA Obtained From Formalin-fixed, Paraffin-embedded Tissue

Article • Journal of Histochemistry & Cytochemistry, July 2008, SAGE Publications

Dr Stephen M Hewitt
Overexpression of CDC25B and LAMC2 mRNA and Protein in Esophageal Squamous Cell Carcinomas and Premalignant Lesions in Subjects from a High-Risk Population in China

Article • Cancer Epidemiology Biomarkers & Prevention, June 2008, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Automated evaluation of HER-2/neu immunohistochemical expression in breast cancer using digital microscopy

Article • May 2008, Institute of Electrical & Electronics Engineers (IEEE)

Dr Stephen M Hewitt
Altered Cytoplasmic-to-Nuclear Ratio of Survivin Is a Prognostic Indicator in Breast Cancer

Article • Clinical Cancer Research, May 2008, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Tissue microarray: A simple technology that has revolutionized research in pathology

Article • Journal of Postgraduate Medicine, January 2008, Medknow

Dr AVNINDER SINGH, Dr Stephen M Hewitt
Frozen Protein Arrays

Article • January 2008, Springer Science + Business Media

Dr Stephen M Hewitt
Aberrant nucleocytoplasmic localization of the retinoblastoma tumor suppressor protein in human cancer correlates with moderate/poor tumor differentiation

Article • Oncogene, December 2007, Nature

Dr Stephen M Hewitt
The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation

Article • Nature Medicine, November 2007, Nature

Dr Stephen M Hewitt
Hormonal Markers in Breast Cancer: Coexpression, Relationship with Pathologic Characteristics, and Risk Factor Associations in a Population-Based Study

Article • Cancer Research, November 2007, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Transactivation of the EGFR by AP-1 Is Induced by Helicobacter pylori in Gastric Cancer

Article • The American Journal of Gastroenterology, October 2007, Nature

Dr Stephen M Hewitt
Liver proteomics for therapeutic drug discovery: Inhibition of the cyclophilin receptor CD147 attenuates sepsis-induced acute renal failure*

Article • Critical Care Medicine, October 2007, Wolters Kluwer Health

Dr Stephen M Hewitt
Variation in breast cancer hormone receptor andHER2levels by etiologic factors: A population-based analysis

Article • International Journal of Cancer, September 2007, Wiley

Dr Stephen M Hewitt
Dissecting the Akt/Mammalian Target of Rapamycin Signaling Network: Emerging Results from the Head and Neck Cancer Tissue Array Initiative

Article • Clinical Cancer Research, September 2007, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Tissue microarrays enabling high-throughput molecular pathology

Article • Current Opinion in Biotechnology, August 2007, Elsevier

Dr Stephen M Hewitt
Layered Peptide Array for Multiplex Immunohistochemistry

Article • Journal of Molecular Diagnostics, July 2007, Elsevier

Dr Stephen M Hewitt
Recommendations for Improved Standardization of Immunohistochemistry

Article • Applied Immunohistochemistry & Molecular Morphology, June 2007, Wolters Kluwer Health

Dr Stephen M Hewitt
Glut-1 as a therapeutic target: increased chemoresistance and HIF-1-independent link with cell turnover is revealed through COMPARE analysis and metabolomic studies

Article • Cancer Chemotherapy and Pharmacology, May 2007, Springer Science + Business Media

Dr Stephen M Hewitt
Expression of EIF3-p48/INT6, TID1 and Patched in cancer, a profiling of multiple tumor types and correlation of expression

Article • Journal of Biomedical Science, March 2007, Springer Science + Business Media

Dr Stephen M Hewitt
Expression of the cytoskeleton linker protein ezrin in human cancers

Article • Clinical & Experimental Metastasis, March 2007, Springer Science + Business Media

Dr CHARLES A POWELL, Dr Stephen M Hewitt
Proteomic expression profiling of thyroid neoplasms

Article • PROTEOMICS - CLINICAL APPLICATIONS, March 2007, Wiley

Dr Stephen M Hewitt
Differences in Risk Factors for Breast Cancer Molecular Subtypes in a Population-Based Study

Article • Cancer Epidemiology Biomarkers & Prevention, March 2007, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Desmoglein 3 as a prognostic factor in lung cancer

Article • Human Pathology, February 2007, Elsevier

Professor Junya Fukuoka, Dr Stephen M Hewitt
Layered expression scanning: Multiplex molecular analysis of diverse life science platforms

Article • Clinica Chimica Acta, February 2007, Elsevier

Dr Stephen M Hewitt
Credentialing Preclinical Pediatric Xenograft Models Using Gene Expression and Tissue Microarray Analysis

Article • Cancer Research, January 2007, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Cell microarray platform for anticancer drug development

Article • Drug Development Research, January 2007, Wiley

Dr Stephen M Hewitt
Optimization of Recovery of RNA From Formalin-fixed, Paraffin-embedded Tissue

Article • Diagnostic Molecular Pathology, December 2006, Wolters Kluwer Health

Dr Stephen M Hewitt
Markers and Tissue Resources for Melanoma: Meeting Report

Article • Cancer Research, November 2006, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Ezrin mediates growth and survival in Ewing’s sarcoma through the AKT/mTOR, but not the MAPK, signaling pathway

Article • Clinical & Experimental Metastasis, September 2006, Springer Science + Business Media

Dr Stephen M Hewitt
Tissue microarrays as a platform for proteomic investigation

Article • Journal of Molecular Histology, September 2006, Springer Science + Business Media

Dr Stephen M Hewitt
Construction and Validation of Tissue Microarrays of Ductal Carcinoma In Situ and Terminal Duct Lobular Units Associated With Invasive Breast Carcinoma

Article • Diagnostic Molecular Pathology, September 2006, Wolters Kluwer Health

Dr Stephen M Hewitt
Biomarker and drug-target discovery using proteomics in a new rat model of sepsis-induced acute renal failure

Article • Kidney International, August 2006, Elsevier

Dr Stephen M Hewitt
High throughput assessment of cells and tissues: Bayesian classification of spectral metrics from infrared vibrational spectroscopic imaging data

Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, July 2006, Elsevier

Dr Stephen M Hewitt
A Multiplex Tissue Immunoblotting Assay for Proteomic Profiling: A Pilot Study of the Normal to Tumor Transition of Esophageal Squamous Cell Carcinoma

Article • Cancer Epidemiology Biomarkers & Prevention, July 2006, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Framework for Parsing, Visualizing and Scoring Tissue Microarray Images

Article • IEEE Transactions on Information Technology in Biomedicine, April 2006, Institute of Electrical & Electronics Engineers (IEEE)

Dr Stephen M Hewitt
Intravenously administered vitamin C as cancer therapy: three cases

Article • Canadian Medical Association Journal, March 2006, Canadian Medical Association (CMA)

Dr Stephen M Hewitt
Spectrum of activity and molecular correlates of response to phosphatidylinositol ether lipid analogues, novel lipid-based inhibitors of Akt

Article • Molecular Cancer Therapeutics, March 2006, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Sepsis-induced organ failure is mediated by different pathways in the kidney and liver: Acute renal failure is dependent on MyD88 but not renal cell apoptosis

Article • Kidney International, March 2006, Elsevier

Dr Stephen M Hewitt
The Role of Interleukin 1 in Growth and Metastasis of Human Cancer Xenografts

Article • Clinical Cancer Research, February 2006, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Tissue microarray analysis of human FRAT1 expression and its correlation with the subcellular localisation of β-catenin in ovarian tumours

Article • British Journal of Cancer, February 2006, Nature

Dr Stephen M Hewitt
Transfer and multiplex immunoblotting of a paraffin embedded tissue

Article • PROTEOMICS, February 2006, Wiley

Dr Stephen M Hewitt
Antiangiogenic and Antitumor Effects of Bevacizumab in Patients With Inflammatory and Locally Advanced Breast Cancer

Article • Journal of Clinical Oncology, January 2006, American Society of Clinical Oncology (ASCO)

Dr Stephen M Hewitt
[20] The Application of Tissue Microarrays in the Validation of Microarray Results

Article • January 2006, Elsevier

Dr Stephen M Hewitt
Automated Confocal Imaging and High-Content Screening for Cytomics

Article • January 2006, Springer Science + Business Media

Dr Stephen M Hewitt
Evaluation of Two Phosphorylation Sites Improves the Prognostic Significance of Akt Activation in Non-Small-Cell Lung Cancer Tumors

Article • Journal of Clinical Oncology, December 2005, American Society of Clinical Oncology (ASCO)

Dr Stephen M Hewitt
Tissues from population-based cancer registries: a novel approach to increasing research potential

Article • Human Pathology, July 2005, Elsevier

Dr Stephen M Hewitt
Tissue microarrays: bridging the gap between research and the clinic

Article • Expert Review of Proteomics, June 2005, Taylor & Francis

Dr Stephen M Hewitt
Infrared spectroscopic imaging for histopathologic recognition

Article • Nature Biotechnology, March 2005, Nature

Dr Stephen M Hewitt
Schedule-dependent Inhibition of Hypoxia-inducible Factor-1 Protein Accumulation, Angiogenesis, and Tumor Growth by Topotecan in U251-HRE Glioblastoma Xenografts

Article • Cancer Research, October 2004, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
A Recurrent Chromosome Breakpoint in Breast Cancer at the NRG1/Neuregulin 1/Heregulin Gene

Article • Cancer Research, October 2004, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Evaluation of Biologic End Points and Pharmacokinetics in Patients With Metastatic Breast Cancer After Treatment With Erlotinib, an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor

Article • Journal of Clinical Oncology, August 2004, American Society of Clinical Oncology (ASCO)

Dr Stephen M Hewitt
High Throughput Fourier Transform Infrared Spectroscopic Imaging for Histopathology

Article • Microscopy and Microanalysis, August 2004, Cambridge University Press

Dr Stephen M Hewitt
Modulation of Tumor-host Interactions, Angiogenesis, and Tumor Growth by Tissue Inhibitor of Metalloproteinase 2 via a Novel Mechanism

Article • Cancer Research, July 2004, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Discovery of Protein Biomarkers for Renal Diseases

Article • Journal of the American Society of Nephrology, July 2004, American Society of Nephrology

Dr Stephen M Hewitt
Chromatin Remodeling Factors and BRM/BRG1 Expression as Prognostic Indicators in Non-Small Cell Lung Cancer

Article • Clinical Cancer Research, July 2004, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
Sil overexpression in lung cancer characterizes tumors with increased mitotic activity

Article • Oncogene, April 2004, Springer Science + Business Media

Dr Stephen M Hewitt
Randomized, Double-Blind, Placebo-Controlled Phase IIB Trial of the Cyclooxygenase Inhibitor Ketorolac as an Oral Rinse in Oropharyngeal Leukoplakia

Article • Clinical Cancer Research, March 2004, American Association for Cancer Research (AACR)

Dr Stephen M Hewitt
The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis

Article • Nature Medicine, January 2004, Nature

Dr Stephen M Hewitt
Peak stimulated insulin secretion is associated with specific changes in gene expression profiles in sporadic insulinomas

Article • Surgery, December 2003, Elsevier

Dr Stephen M Hewitt
Ethyl pyruvate decreases sepsis-induced acute renal failure and multiple organ damage in aged mice

Article • Kidney International, November 2003, Elsevier

Dr Stephen M Hewitt
Comparative Evaluation of Super High-Resolution CT Scan and Virtual Bronchoscopy for the Detection of Tracheobronchial Malignancies*

Article • CHEST Journal, November 2003, Elsevier

Dr Stephen M Hewitt
Renal Tumors in the Birt-Hogg-Dubé Syndrome

Article • The American Journal of Surgical Pathology, December 2002, Wolters Kluwer Health

Dr Stephen M Hewitt
Post-analysis follow-up and validation of microarray experiments

Article • Nature Genetics, December 2002, Nature

Dr Stephen M Hewitt
Frozen protein arrays: A new method for arraying and detecting recombinant and native tissue proteins

Article • PROTEOMICS, November 2002, Wiley

Dr Stephen M Hewitt
Microarray Gene Expression Analysis of Murine Tumor Heterogeneity Defined by Dynamic Contrast-Enhanced MRI

Article • Molecular Imaging, July 2002, SAGE Publications

Dr Stephen M Hewitt
Erratum

Article • Cancer, May 2002, Wiley

Dr Stephen M Hewitt
Retroviral gene transfer of interferon-inducible protein 10 inhibits growth of human melanoma xenografts

Article • International Journal of Cancer, March 2002, Wiley

Dr Stephen M Hewitt
Specimen Morcellation after Laparoscopic Radical Nephrectomy: Confirmation of Histologic Diagnosis Using Needle Biopsy

Article • Journal of Endourology, March 2002, Mary Ann Liebert Inc

Dr Stephen M Hewitt
Differential expression of the mismatch repair genehMSH2 in malignant prostate tissue is associated with cancer recurrence

Article • Cancer, January 2002, Wiley

Dr Stephen M Hewitt
Interleukin-10 inhibits ischemic and cisplatin-induced acute renal injury

Article • Kidney International, December 2001, Elsevier

Dr Stephen M Hewitt
Intramedullary Spinal Cord Metastasis from Renal Cell Carcinoma

Article • Clinical Nuclear Medicine, October 2001, Wolters Kluwer Health

Dr Stephen M Hewitt
Birt-Hogg-Dubé Syndrome, a Genodermatosis Associated with Spontaneous Pneumothorax and Kidney Neoplasia, Maps to Chromosome 17p11.2

Article • The American Journal of Human Genetics, October 2001, Elsevier

Dr Stephen M Hewitt
INTRAOPERATIVE ULTRASOUND DURING RENAL PARENCHYMAL SPARING SURGERY FOR HEREDITARY RENAL CANCERS:: A 10-YEAR EXPERIENCE

Article • The Journal of Urology, February 2001, Elsevier

Dr Stephen M Hewitt
Molecular cytogenetic characterization of early and late renal cell carcinomas in Von Hippel-Lindau disease

Article • Genes Chromosomes and Cancer, January 2001, Wiley

Dr Stephen M Hewitt
Endothelial Monocyte Activating Polypeptide II Induces Endothelial Cell Apoptosis and May Inhibit Tumor Angiogenesis

Article • Microvascular Research, July 2000, Elsevier

Dr Stephen M Hewitt
The Angiogenesis Inhibitor, Endostatin, Does Not Affect Murine Cutaneous Wound Healing

Article • Journal of Surgical Research, June 2000, Elsevier

Dr Stephen M Hewitt
Utilization of microdissection and the polymerase chain reaction for the diagnosis of adrenal cortical carcinoma in fine-needle aspiration cytology

Article • Cancer, August 1999, Wiley

Dr Stephen M Hewitt
Differential Function of Wilms Tumor Gene WT1 Splice Isoforms in Transcriptional Regulation

Article • Journal of Biological Chemistry, April 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

Dr Stephen M Hewitt
Transcriptional Silencer of the Wilms' Tumor Gene WT1 Contains an Alu Repeat

Article • Journal of Biological Chemistry, July 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

Dr Stephen M Hewitt
Design, Construction, and Use of Tissue Microarrays

Article • Springer Science + Business Media

Dr Stephen M Hewitt

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