All Stories

  1. ARID1A in Gynecologic Precancers and Cancers
  2. Correction: Randomised phase II trial of weekly ixabepilone ± biweekly bevacizumab for platinum-resistant or refractory ovarian/fallopian tube/primary peritoneal cancer
  3. Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer
  4. Uterine leiomyosarcomas harboring MAP2K4 gene amplification are sensitive in vivo to PLX8725, a novel MAP2K4 inhibitor
  5. Corrigendum to “Elimusertib (BAY1895344), a novel ATR inhibitor, demonstrates in vivo activity in ATRX mutated models of uterine leiomyosarcoma”
  6. The Poly (ADP-ribose) polymerase inhibitor olaparib and pan-ErbB inhibitor neratinib are highly synergistic in HER2 overexpressing epithelial ovarian carcinoma in vitro and in vivo
  7. Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody–drug conjugate with topoisomerase I inhibitor payload, shows antitumor activity in uterine and ovarian carcinosarcoma with HER2/neu expression
  8. Ovarian and uterine carcinosarcomas are sensitive in vitro and in vivo to elimusertib, a novel ataxia-telangiectasia and Rad3-related (ATR) kinase inhibitor
  9. What role does adjuvant therapy play in the management of endometrial cancer?
  10. Elimusertib (BAY1895344), a novel ATR inhibitor, demonstrates in vivo activity in ATRX mutated models of uterine leiomyosarcoma
  11. Intersections of endocrine pathways and the epithelial mesenchymal transition in endometrial cancer
  12. Synergistic activity of neratinib in combination with olaparib in uterine serous carcinoma overexpressing HER2/neu
  13. Homologous recombination deficiency (HRD) signature-3 in ovarian and uterine carcinosarcomas correlates with preclinical sensitivity to Olaparib, a poly (adenosine diphosphate [ADP]- ribose) polymerase (PARP) inhibitor
  14. Randomised phase II trial of weekly ixabepilone ± biweekly bevacizumab for platinum-resistant or refractory ovarian/fallopian tube/primary peritoneal cancer
  15. A phase 2 evaluation of pembrolizumab for recurrent Lynch‐like versus sporadic endometrial cancers with microsatellite instability
  16. Prognostic impact of mismatch repair deficiency in high- and low-intermediate-risk, early-stage endometrial cancer following vaginal brachytherapy
  17. DHES0815A, a novel antibody-drug conjugate targeting HER2/neu, is highly active against uterine serous carcinomas in vitro and in vivo
  18. Trastuzumab tolerability in the treatment of advanced (stage III-IV) or recurrent uterine serous carcinomas that overexpress HER2/neu
  19. A phase II evaluation of pembrolizumab in recurrent microsatellite instability-high (MSI-H) endometrial cancer patients with Lynch-like versus MLH-1 methylated characteristics (NCT02899793)
  20. Integrated mutational landscape analysis of uterine leiomyosarcomas
  21. Sex Hormone, Insulin and Insulin-like Growth Factor in Recurrence of High Stage Endometrial Cancer
  22. Financial toxicity in patients with gynecologic malignancies: a cross sectional study
  23. Population-Based Screening for Endometrial Cancer: Human vs. Machine Intelligence
  24. Prescribed medical cannabis in women with gynecologic malignancies: A single-institution survey-based study
  25. Vulnerability of ARID1A deficient cancer cells to pyrimidine synthesis blockade
  26. Derangements in HUWE1/c-MYC pathway confer sensitivity to the BET bromodomain inhibitor GS-626510 in uterine cervical carcinoma
  27. In vitro and in vivo activity of sacituzumab govitecan, an antibody-drug conjugate targeting trophoblast cell-surface antigen 2 (Trop-2) in uterine serous carcinoma
  28. Cervical carcinomas that overexpress human trophoblast cell-surface marker (Trop-2) are highly sensitive to the antibody-drug conjugate sacituzumab govitecan
  29. Sacituzumab govitecan, an antibody‐drug conjugate targeting trophoblast cell‐surface antigen 2, shows cytotoxic activity against poorly differentiated endometrial adenocarcinomas in vitro and in vivo
  30. Stage III uterine serous carcinoma: modern trends in multimodality treatment
  31. Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy
  32. PARP-1 activity (PAR) determines the sensitivity of cervical cancer to olaparib
  33. Precision Therapy for Aggressive Endometrial Cancer by Reactivation of Protein Phosphatase 2A
  34. Neutrophil count predicts mortality in women with aggressive uterine cancer.
  35. Stratifying Ovarian Cancer Risk Using Personal Health Data
  36. PI3K oncogenic mutations mediate resistance to afatinib in HER2/neu overexpressing gynecological cancers
  37. Correction for Li et al., Mutational landscape of primary, metastatic, and recurrent ovarian cancer reveals c-MYC gains as potential target for BET inhibitors
  38. Mutational landscape of primary, metastatic, and recurrent ovarian cancer reveals c-MYC gains as potential target for BET inhibitors
  39. Inhibition of BET Bromodomain Proteins with GS-5829 and GS-626510 in Uterine Serous Carcinoma, a Biologically Aggressive Variant of Endometrial Cancer
  40. Impact of carboplatin hypersensitivity and desensitization on patients with recurrent ovarian cancer
  41. A novel multiple biomarker panel for the early detection of high-grade serous ovarian carcinoma
  42. Evaluation of a Streamlined Oncologist-Led BRCA Mutation Testing and Counseling Model for Patients With Ovarian Cancer
  43. In Vitro and In Vivo Activity of IMGN853, an Antibody–Drug Conjugate Targeting Folate Receptor Alpha Linked to DM4, in Biologically Aggressive Endometrial Cancers
  44. Female Sex Hormone Receptor Profiling in Uterine Adenosarcomas
  45. IGF2 is a prognostic biomarker in aggressive uterine cancer
  46. Superior in vitro and in vivo activity of trastuzumab-emtansine (T-DM1) in comparison to trastuzumab, pertuzumab and their combination in epithelial ovarian carcinoma with high HER2/neu expression
  47. SYD985, a novel duocarmycin-based HER2-targeting antibody-drug conjugate, shows promising antitumor activity in epithelial ovarian carcinoma with HER2/Neu expression
  48. Genetics of Clear Cell Endometrial Cancer
  49. RNA-seq Identification of RACGAP1 as a Metastatic Driver in Uterine Carcinosarcoma
  50. Insulin/IGF and sex hormone axes in human endometrium and associations with endometrial cancer risk factors
  51. Retreatment with aromatase inhibitor therapy in the management of granulosa cell tumor
  52. Designing a broad-spectrum integrative approach for cancer prevention and treatment
  53. Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds
  54. PTEN expression in benign human endometrial tissue and cancer in relation to endometrial cancer risk factors
  55. IGF2 signaling and regulation in cancer
  56. The impact of obesity on prostate cancer recurrence observed after exclusion of diabetics
  57. Transforming Growth Factor β1 and Extracellular Matrix Protease Expression in the Uterosacral Ligaments of Patients With and Without Pelvic Organ Prolapse
  58. Insulin-Like Growth Factor 2 Silencing Restores Taxol Sensitivity in Drug Resistant Ovarian Cancer
  59. Phase II trial of adjuvant pelvic radiation “sandwiched” between combination paclitaxel and carboplatin in women with uterine papillary serous carcinoma
  60. Phase II trial of adjuvant pelvic radiation “sandwiched” between ifosfamide or ifosfamide plus cisplatin in women with uterine carcinosarcoma
  61. Clinical utility of chromogranin a and octreotide in large cell neuro endocrine carcinoma of the uterine corpus
  62. Downregulation of Filamin A Interacting Protein 1-Like is Associated with Promoter Methylation and Induces an Invasive Phenotype in Ovarian Cancer
  63. Performance of Serum CA125 as a Prognostic Biomarker in Patients With Uterine Papillary Serous Carcinoma
  64. Co-expression of GPR30 and ERβ and their association with disease progression in uterine carcinosarcoma
  65. Insulin-like Growth Factor 2 Expression Modulates Taxol Resistance and Is a Candidate Biomarker for Reduced Disease-Free Survival in Ovarian Cancer
  66. Extragenital adenosarcoma: A case report, review of the literature, and management discussion
  67. A phase II study of weekly topotecan and docetaxel in heavily treated patients with recurrent uterine and ovarian cancers
  68. Tissue microarray analysis of hormonal signaling pathways in uterine carcinosarcoma
  69. Serum CA125 predicts extrauterine disease and survival in uterine carcinosarcoma
  70. Accuracy of preoperative endometrial sampling for the detection of high-grade endometrial tumors
  71. Survival and toxicity differences between 5-day and weekly cisplatin in patients with locally advanced cervical cancer
  72. Potentiation of Taxol Efficacy by Discodermolide in Ovarian Carcinoma Xenograft-Bearing Mice
  73. Consolidation therapy for ovarian cancer
  74. Total laparoscopic hysterectomy for oncological indications with outcomes stratified by age
  75. Selective incorporation of total laparoscopic hysterectomy for adnexal pathology and body mass index
  76. Total laparoscopic hysterectomy: body mass index and outcomes
  77. Liposomal Doxorubicin for Treatment of Metastatic Chemorefractory Vulvar Adenocarcinoma