All Stories

  1. Decoding Enzyme–Inhibitor Kinetic Mechanisms by Isothermal Titration Calorimetry: The Case of SARS-CoV-2 3CL pro
  2. Author Correction: An isothermal calorimetry assay for determining steady state kinetic and Ensitrelvir inhibition parameters for SARS-CoV-2 3CL-protease
  3. Preferential survival of prebiotic metallopeptides in the presence of ultraviolet light
  4. An isothermal calorimetry assay for determining steady state kinetic and Ensitrelvir inhibition parameters for SARS-CoV-2 3CL-protease
  5. Exploring the conformational space of the mobile flap in Sporosarcina pasteurii urease by cryo-electron microscopy
  6. An isothermal calorimetry assay for determining steady state kinetic and enzyme inhibition parameters for SARS-CoV-2 3CL-protease
  7. Is bismuth(iii) able to inhibit the activity of urease? Puzzling results in the quest for soluble urease complexes for agrochemical and medicinal applications
  8. Metal selectivity and translocation mechanism characterization in proteoliposomes of the transmembrane NiCoT transporter NixA from Helicobacter pylori
  9. Protocol for production and purification of SARS-CoV-2 3CLpro
  10. The structure of the high-affinity nickel-binding site in the Ni,Zn-HypA•UreE2 complex
  11. Inhibition of Urease by Hydroquinones: A Structural and Kinetic Study
  12. The Ni(II)-Binding Activity of the Intrinsically Disordered Region of Human NDRG1, a Protein Involved in Cancer Development
  13. Thiocarbamoyl Disulfides as Inhibitors of Urease and Ammonia Monooxygenase: Crystal Engineering for Novel Materials
  14. Structure, dynamics, and function of SrnR, a transcription factor for nickel-dependent gene expression
  15. Nickel import and export in the human pathogenHelicobacter pylori, perspectives from molecular modelling
  16. Nickel as a virulence factor in the Class I bacterial carcinogen, Helicobacter pylori
  17. Facilitating Nitrification Inhibition through Green, Mechanochemical Synthesis of a Novel Nitrapyrin Complex
  18. Inhibition of Urease, a Ni‐Enzyme: The Reactivity of a Key Thiol With Mono‐ and Di‐Substituted Catechols Elucidated by Kinetic, Structural, and Theoretical Studies
  19. Inhibition of Urease, a Ni‐Enzyme: The Reactivity of a Key Thiol With Mono‐ and Di‐Substituted Catechols Elucidated by Kinetic, Structural, and Theoretical Studies
  20. Correction to: The model structure of the copper-dependent ammonia Monooxygenase
  21. Medicinal Au(i) compounds targeting urease as prospective antimicrobial agents: unveiling the structural basis for enzyme inhibition
  22. The model structure of the copper-dependent ammonia monooxygenase
  23. The structure-based reaction mechanism of urease, a nickel dependent enzyme: tale of a long debate
  24. Nickel and GTP Modulate Helicobacter pylori UreG Structural Flexibility
  25. Targeting the Protein Tunnels of the Urease Accessory Complex: A Theoretical Investigation
  26. Intrinsic disorder in the nickel-dependent urease network
  27. Bioinorganic Chemistry of Nickel
  28. Soyuretox, an Intrinsically Disordered Polypeptide Derived from Soybean (Glycine Max) Ubiquitous Urease with Potential Use as a Biopesticide
  29. Urease Inhibitory Potential and Soil Ecotoxicity of Novel “Polyphenols–Deep Eutectic Solvents” Formulations
  30. The Impact of pH on Catalytically Critical Protein Conformational Changes: The Case of the Urease, a Nickel Enzyme
  31. Multifunctional Urea Cocrystal with Combined Ureolysis and Nitrification Inhibiting Capabilities for Enhanced Nitrogen Management
  32. The Structure of the Elusive Urease-Urea Complex Unveils the Mechanism of a Paradigmatic Nickel-Dependent Enzyme
  33. The Structure of the Elusive Urease–Urea Complex Unveils the Mechanism of a Paradigmatic Nickel‐Dependent Enzyme
  34. The carbon monoxide dehydrogenase accessory protein CooJ is a histidine-rich multidomain dimer containing an unexpected  Ni(II)-binding site
  35. Insights into Urease Inhibition by N-(n-Butyl) Phosphoric Triamide through an Integrated Structural and Kinetic Approach
  36. Novel Dual-Action Plant Fertilizer and Urease Inhibitor: Urea·Catechol Cocrystal. Characterization and Environmental Reactivity
  37. Inhibition Mechanism of Urease by Au(III) Compounds Unveiled by X-ray Diffraction Analysis
  38. The structure of urease inactivated by Ag(i): a new paradigm for enzyme inhibition by heavy metals
  39. Smart urea ionic co-crystals with enhanced urease inhibition activity for improved nitrogen cycle management
  40. Structural analysis of the interaction between Jaburetox, an intrinsically disordered protein, and membrane models
  41. Urease Inhibition in the Presence of N-(n-Butyl)thiophosphoric Triamide, a Suicide Substrate: Structure and Kinetics
  42. The relationship between folding and activity in UreG, an intrinsically disordered enzyme
  43. Development of a multisite model for Ni(II) ion in solution from thermodynamic and kinetic data
  44. Glutamate Ligation in the Ni(II)- and Co(II)-Responsive Escherichia coli Transcriptional Regulator, RcnR
  45. Protein Tunnels: The Case of Urease Accessory Proteins
  46. The CO dehydrogenase accessory protein CooT is a novel nickel-binding protein
  47. Nickel impact on human health: An intrinsic disorder perspective
  48. Inactivation of urease by catechol: Kinetics and structure
  49. Surface plasmon resonance and isothermal titration calorimetry to monitor the Ni(II)-dependent binding of Helicobacter pylori NikR to DNA
  50. On the role of a specific insert in acetate permeases (ActP) for tellurite uptake in bacteria: functional and structural studies
  51. Kinetic and structural studies reveal a unique binding mode of sulfite to the nickel center in urease
  52. Inactivation of urease by 1,4-benzoquinone: chemistry at the protein surface
  53. Isothermal Titration Calorimetry to Characterize Enzymatic Reactions
  54. Evolution of Macromolecular Docking Techniques: The Case Study of Nickel and Iron Metabolism in Pathogenic Bacteria
  55. On the interaction of Helicobacter pylori NikR, a Ni(II)-responsive transcription factor, with the urease operator: in solution and in silico studies
  56. Intrinsic disorder and metal binding in UreG proteins from Archae hyperthermophiles: GTPase enzymes involved in the activation of Ni(II) dependent urease
  57. Pliable natural biocide: Jaburetox is an intrinsically disordered insecticidal and fungicidal polypeptide derived from jack bean urease
  58. Nickel-responsive transcriptional regulators
  59. Promiscuous Nickel Import in Human Pathogens: Structure, Thermodynamics, and Evolution of Extracytoplasmic Nickel-Binding Proteins
  60. The conformational response to Zn(II) and Ni(II) binding of Sporosarcina pasteurii UreG, an intrinsically disordered GTPase
  61. Molecular landscape of the interaction between the urease accessory proteins UreE and UreG
  62. Fluoride inhibition of Sporosarcina pasteurii urease: structure and thermodynamics
  63. Nonredox Nickel Enzymes
  64. Hot Biological Catalysis: Isothermal Titration Calorimetry to Characterize Enzymatic Reactions
  65. FeON-FeOFF: the Helicobacter pylori Fur regulator commutates iron-responsive transcription by discriminative readout of opposed DNA grooves
  66. Nickel binding properties of Helicobacter pylori UreF, an accessory protein in the nickel-based activation of urease
  67. Selectivity of Ni(II) and Zn(II) binding to Sporosarcina pasteurii UreE, a metallochaperone in the urease assembly: a calorimetric and crystallographic study
  68. Structure of the UreD–UreF–UreG–UreE complex in Helicobacter pylori: a model study
  69. Conformational Fluctuations of UreG, an Intrinsically Disordered Enzyme
  70. Biogeochemical processes and geotechnical applications: progress, opportunities and challenges
  71. The crystal structure of Sporosarcina pasteurii urease in a complex with citrate provides new hints for inhibitor design
  72. Urease
  73. Nickel and Human Health
  74. Engineered biosealant strains producing inorganic and organic biopolymers
  75. Crystallographic and X-ray absorption spectroscopic characterization of Helicobacter pylori UreE bound to Ni 2+ and Zn 2+ reveals a role for the disordered C-terminal arm in metal trafficking
  76. Biochemical and structural studies on native and recombinant Glycine max UreG: a detailed characterization of a plant urease accessory protein
  77. Insights in the (un)structural organization of Bacillus pasteurii UreG, an intrinsically disordered GTPase enzyme
  78. Intrinsic Fluorescence of Intrinsically Disordered Proteins
  79. Denaturant-Induced Conformational Transitions in Intrinsically Disordered Proteins
  80. Unraveling the Helicobacter pylori UreG zinc binding site using X-ray absorption spectroscopy (XAS) and structural modeling
  81. Metal Ion-Mediated DNA-Protein Interactions
  82. Model Structures of Helicobacter pylori UreD(H) Domains: A Putative Molecular Recognition Platform
  83. Chemistry of Ni2+in Urease: Sensing, Trafficking, and Catalysis
  84. Zinc Inhibition of Bacterial Cytochrome bc1 Reveals the Role of Cytochrome b E295 in Proton Release at the Qo Site
  85. Interaction of Selenoprotein W with 14-3-3 Proteins: A Computational Approach
  86. Holo-Ni2+Helicobacter pylori NikR contains four square-planar nickel-binding sites at physiological pH
  87. Computational Study of the DNA-Binding Protein Helicobacter pylori NikR: The Role of Ni 2+ 2 2 Francesco Musiani and Branimir Bertoša contributed equally to the simulations presented here.
  88. Nickel Enzymes/Models
  89. Helicobacter pylori UreE, a urease accessory protein: specific Ni 2+ - and Zn 2+ -binding properties and interaction with its cognate UreG
  90. The RNA Hydrolysis and the Cytokinin Binding Activities of PR-10 Proteins Are Differently Performed by Two Isoforms of the Pru p 1 Peach Major Allergen and Are Possibly Functionally Related
  91. Zn2+-linked dimerization of UreG fromHelicobacter pylori, a chaperone involved in nickel trafficking and urease activation
  92. High-Affinity Ni2+ Binding Selectively Promotes Binding of Helicobacter pylori NikR to Its Target Urease Promoter
  93. Structural Characterization of Binding of Cu(II) to Tau Protein †
  94. High resolution crystal structure of Rubrivivax gelatinosus cytochrome c′
  95. A model-based proposal for the role of UreF as a GTPase-activating protein in the urease active site biosynthesis
  96. Biochemical Studies on Mycobacterium tuberculosis UreG and Comparative Modeling Reveal Structural and Functional Conservation among the Bacterial UreG Family †
  97. The Ni2+ binding properties of Helicobacter pylori NikR
  98. Intrinsically Disordered Structure of Bacillus pasteurii UreG As Revealed by Steady-State and Time-Resolved Fluorescence Spectroscopy †
  99. Low-Temperature EPR and Mössbauer Spectroscopy of Two Cytochromes with His–Met Axial Coordination Exhibiting HALS Signals
  100. An Italian contribution to structural genomics: Understanding metalloproteins
  101. The Nickel Site of Bacillus pasteurii UreE, a Urease Metallo-Chaperone, As Revealed by Metal-Binding Studies and X-ray Absorption Spectroscopy †
  102. Jack bean (Canavalia ensiformis) urease. Probing acid–base groups of the active site by pH variation
  103. High potential iron–sulfur proteins and their role as soluble electron carriers in bacterial photosynthesis: tale of a discovery
  104. Structure of the Intermolecular Complex between Plastocyanin and Cytochromeffrom Spinach
  105. UreG, a Chaperone in the Urease Assembly Process, Is an Intrinsically Unstructured GTPase That Specifically Binds Zn 2+
  106. The Asn 38−Cys 84 H-Bond in Plastocyanin
  107. Nickel trafficking: insights into the fold and function of UreE, a urease metallochaperone☆
  108. Preparation and reactivity studies of synthetic microperoxidases containing b-type heme
  109. Molecular Details of Urease Inhibition by Boric Acid:  Insights into the Catalytic Mechanism
  110. Electron Transfer from HiPIP to the Photooxidized Tetraheme Cytochrome Subunit of Allochromatium vinosum Reaction Center:  New Insights from Site-Directed Mutagenesis and Computational Studies †
  111. Structure ofRhodoferax fermentanshigh-potential iron–sulfur protein solved by MAD
  112. Nickel trafficking and urease: recent developments
  113. Structural Basis for the Molecular Properties of Cytochrome c 6 †
  114. New Insights into the Mechanism of Purple Acid Phosphatase through 1 H NMR Spectroscopy of the Recombinant Human Enzyme
  115. NMR Solution Structure, Backbone Mobility, and Homology Modeling ofc-Type Cytochromes from Gram-Positive Bacteria
  116. Molecular characterization of Bacillus pasteurii UreE, a metal-binding chaperone for the assembly of the urease active site
  117. Structural Basis for Ni2+Transport and Assembly of the Urease Active Site by the Metallochaperone UreE from Bacillus pasteurii
  118. Structure-based rationalization of urease inhibition by phosphate: novel insights into the enzyme mechanism
  119. Backbone Dynamics of Plastocyanin in Both Oxidation States: SOLUTION STRUCTURE OF THE REDUCED FORM AND COMPARISON WITH THE OXIDIZED STATE
  120. The First Solution Structure of a Paramagnetic Copper(II) Protein:  The Case of Oxidized Plastocyanin from the Cyanobacterium Synechocystis PCC6803
  121. Structure-based computational study of the catalytic and inhibition mechanisms of urease
  122. Crystal Structure of OxidizedBacillus pasteuriiCytochromec553at 0.97-Å Resolution†
  123. The complex of Bacillus pasteurii urease with acetohydroxamate anion from X-ray data at 1.55 Å resolution
  124. Cytochrome c-553 from the Alkalophilic Bacterium Bacillus pasteurii Has the Primary Structure Characteristics of a Lipoprotein
  125. Structural properties of the nickel ions in urease: novel insights into the catalytic and inhibition mechanisms
  126. Probing Structural and Electronic Properties of the Oxidized [Fe 4 S 4 ] 3+ Cluster of Ectothiorhodospira halophila iso-II High-Potential Iron−Sulfur Protein by ENDOR Spectroscopy
  127. High-Field NMR Studies of Oxidized Blue Copper Proteins:  The Case of Spinach Plastocyanin
  128. A new proposal for urease mechanism based on the crystal structures of the native and inhibited enzyme from Bacillus pasteurii: why urea hydrolysis costs two nickels
  129. On the role of high-potential iron–sulfur proteins and cytochromes in the respiratory chain of two facultative phototrophs
  130. On the Role of Soluble Redox Carriers Alternative to Cytochrome c2 As Donors to Tetraheme-Type Reaction Centers and Cytochrome Oxidases
  131. Immobilization of jack bean urease on hydroxyapatite: urease immobilization in alkaline soils
  132. Modulation of Bacillus pasteurii cytochrome c 553 reduction potential by structural and solution parameters
  133. The complex of Bacillus pasteurii urease with β-mercaptoethanol from X-ray data at 1.65-Å resolution
  134. Kinetic properties and stability of potato acid phosphatase immobilized on Ca-polygalacturonate
  135. Crystallization and preliminary high-resolution X-ray diffraction analysis of native and β-mercaptoethanol-inhibited urease from Bacillus pasteurii
  136. Crystallization and preliminary X-ray diffraction analysis of cytochromec′ fromRubrivivax gelatinosusat 1.3 Å resolution
  137. Coordination sphere versus protein environment as determinants of electronic and functional properties of iron-sulfur proteins
  138. Cyclic voltammetry and spectroelectrochemistry of cytochrome c8 from Rubrivivax gelatinosus. Implications in photosynthetic electron transfer
  139. Crystals of cytochrome c‐553 from Bacillus pasteurii show diffraction to 0.97 å resolution
  140. The Primary Structure of Rhodoferax fermentans High-Potential Iron-Sulfur Protein, an Electron Donor to the Photosynthetic Reaction Center
  141. Kinetics of photo-induced electron transfer from high-potential iron-sulfur protein to the photosynthetic reaction center of the purple phototroph Rhodoferax fermentans.
  142. X-ray Absorption Spectroscopy Study of Native and Phenylphosphorodiamidate-Inhibited Bacillus pasteurii Urease
  143. Urease from the soil bacterium Bacillus pasteurii: Immobilization on Ca-polygalacturonate
  144. Bacillus pasteurii urease: A heteropolymeric enzyme with a binuclear nickel active site
  145. 1H NMR of High-Potential Iron-Sulfur Protein from the Purple Non-Sulfur Bacterium Rhodoferax fermentans
  146. Rationalization of the reduction potentials within the series of the high potential iron-sulfur proteins
  147. Isolation, Characterization, and Functional Role of the High-Potential Iron-Sulfur Protein (HiPIP) from Rhodoferax fermentans
  148. The high potential iron-sulfur protein (HiPIP) from Rhodoferax fermentans is competent in photosynthetic electron transfer
  149. Oxidized and Reduced [Fe2Q2] (Q = S, Se) Cores of Spinach Ferredoxin: a Comparative Study Using 1H NMR Spectroscopy
  150. The electronic structure of iron-sulfur [Fe4S4]3+ clusters in proteins. An investigation of the oxidized high-potential iron-sulfur protein II from Ectothiorhodospira vacuolata
  151. NMR of Polymetallic Systems in Proteins
  152. Synthetic nickel-containing heterometal cubane-type clusters with NiFe3Q4 cores (Q = sulfur, selenium)
  153. On the structure of the nickel/iron/sulfur center of the carbon monoxide dehydrogenase from Rhodospirillum rubrum: an x-ray absorption spectroscopy study.
  154. cis- and trans-Dichloro chelate complexes of niobium(IV): synthesis and structure of trans-dichloro[NN′-ethylenebis(acetylacetonylideneiminato)-(2–)]niobium(IV) and cis-dichloro{7,16-dihydro-6,8,15,17-tetramethyldibenzo-[b,i][1,4,...
  155. Five-co-ordinate magnesium complexes: synthesis and structure of quadridentate Schiff-base derivatives
  156. Ion pair complexes form the reduction of metal(II)-dibenzotetramethyltetra-aza[14]annulene complexes
  157. A New Class of Organozirconium(IV) Compounds: Alkyl Derivatives of Tetramethyltetraazadibenzo[14]annulenatozirconium(IV)
  158. Reduzierte Cobalt-meso-tetraphenylporphyrin-Komplexe: Synthese und Struktur von [Na(thf)3]2[Co(TPP)]
  159. Urease: Recent Insights on the Role of Nickel
  160. Subsite-Specific Structures and Reactions in Native and Synthetic [4Fe-4S] Cubane-Type Clusters