All Stories

  1. Helix-loop-helix peptide foldamers and their use in the construction of hydrolase mimetics
  2. Frontispiece: Sequence Engineering to Control the Helix Handedness of Peptide Foldamers
  3. Sequence Engineering to Control the Helix Handedness of Peptide Foldamers
  4. Bioactive Macrocyclic Inhibitors of the PD-1/PD-L1 Immune Checkpoint
  5. Discovery of new leads against Mycobacterium tuberculosis using scaffold hopping and shape based similarity
  6. Aminophosphinates against Helicobacter pylori ureolysis—Biochemical and whole-cell inhibition characteristics
  7. Novel organophosphorus scaffolds of urease inhibitors obtained by substitution of Morita-Baylis-Hillman adducts with phosphorus nucleophiles
  8. Potent covalent inhibitors of bacterial urease identified by activity-reactivity profiling
  9. Controlling the Helix Handedness of ααβ-Peptide Foldamers through Sequence Shifting
  10. Controlling the Helix Handedness of ααβ-Peptide Foldamers through Sequence Shifting
  11. 1,2-Benzisoselenazol-3(2H)-one Derivatives As a New Class of Bacterial Urease Inhibitors
  12. A structural insight into the P1S1 binding mode of diaminoethylphosphonic and phosphinic acids, selective inhibitors of alanine aminopeptidases
  13. Phytotoxicity of aminobisphosphonates targeting bothδ1-pyrroline-5-carboxylate reductase and glutamine synthetase
  14. Peptide-based inhibitors of protein–protein interactions
  15. Zwitterionic Phosphorylated Quinines as Chiral Solvating Agents for NMR Spectroscopy
  16. Bisphosphonic acids as effective inhibitors of Mycobacterium tuberculosis glutamine synthetase
  17. Bis(aminomethyl)phosphinic Acid, a Highly Promising Scaffold for the Development of Bacterial Urease Inhibitors
  18. Peptides Containing β-Amino Acid Patterns: Challenges and Successes in Medicinal Chemistry
  19. Structure-Guided, Single-Point Modifications in the Phosphinic Dipeptide Structure Yield Highly Potent and Selective Inhibitors of Neutral Aminopeptidases
  20. Crystal structure of Aminopeptidase N in complex with the phosphonic acid analogue of leucine (D-(S)-LeuP)
  21. A three-component synthesis of aminomethylenebis-H-phosphinates
  22. Replacement of Thr 32 and Gln 34 in the C -Terminal Neuropeptide Y Fragment 25–36 by cis -Cyclobutane and cis -Cyclopentane β-Amino Acids Shifts Selectivity toward the Y 4 Receptor
  23. Toward very potent, non-covalent organophosphonate inhibitors of cathepsin C and related enzymes by 2-amino-1-hydroxy-alkanephosphonates dipeptides
  24. Synthesis and Evaluation of Effective Inhibitors of Plant δ1-Pyrroline-5-carboxylate Reductase
  25. Erratum to: The crystal structure of Sporosarcina pasteurii urease in a complex with citrate provides new hints for inhibitor design
  26. The crystal structure of Sporosarcina pasteurii urease in a complex with citrate provides new hints for inhibitor design
  27. An integrated approach to the ligand binding specificity of Neisseria meningitidis M1 alanine aminopeptidase by fluorogenic substrate profiling, inhibitory studies and molecular modeling
  28. Phosphorylation as a method of tuning the enantiodiscrimination potency of quinine-An NMR study
  29. α,β- und α,α,β,β-Peptidfoldamere basierend auf cis-β-Aminocyclopentancarbonsäure
  30. Unique α,β- and α,α,β,β-Peptide Foldamers Based on cis-β-Aminocyclopentanecarboxylic Acid
  31. Remarkable Potential of the α-Aminophosphonate/Phosphinate Structural Motif in Medicinal Chemistry
  32. δ1-Pyrroline-5-carboxylate reductase as a new target for therapeutics: inhibition of the enzyme from Streptococcus pyogenes and effects in vivo
  33. N-substituted aminomethanephosphonic and aminomethane-P-methylphosphinic acids as inhibitors of ureases
  34. Urease inhibitors as potential drugs for gastric and urinary tract infections: a patent review
  35. Computer-Aided Optimization of Phosphinic Inhibitors of Bacterial Ureases
  36. Enantiodifferentiation of α-hydroxyalkanephosphonic acids in31P NMR with application of α-cyclodextrin as chiral discriminating agent
  37. Cinchona alkaloids as privileged chiral solvating agents for the enantiodiscrimination of N-protected aminoalkanephosphonates—a comparative NMR study
  38. Insight into the mechanism of three component condensation leading to aminomethylenebisphosphonates
  39. Effectiveness and mode of action of phosphonate inhibitors of plant glutamine synthetase
  40. Design, Synthesis, and Evaluation of Novel Organophosphorus Inhibitors of Bacterial Ureases
  41. Inhibitors of Glutamine Synthetase and their Potential Application in Medicine
  42. Tailoring the Structure of Aminobisphosphonates To Target Plant P5C Reductase
  43. Organophosphorus Supramolecular Chemistry. Part 2. Organophosphorus Receptors
  44. Chiral discrimination of ethyl and phenyl N-benzyloxycarbonylaminophosphonates by cyclodextrins
  45. Plant P5C Reductase as a New Target for Aminomethylenebisphosphonates
  46. Analysis of pD-Dependent complexation ofN-benzyloxycarbonylaminophosphonic acids by α-cyclodextrin. Enantiodifferentiation of phosphonic acid pKa values
  47. Enantiodifferentiation of N-benzyloxycarbonylaminophosphonic and phosphinic acids and their esters using cyclodextrins by means of capillary electrophoresis
  48. Organophosphorus Supramolecular Chemistry Part 1. Receptors for Organophosphorus Compounds
  49. Computer-aided analysis of the interactions of glutamine synthetase with its inhibitors
  50. Phosphinothricin Analogues as Inhibitors of Plant Glutamine Synthetases
  51. Computer-Aided Analysis and Design of Phosphonic and Phosphinic Enzyme Inhibitors as Potential Drugs and Agrochemicals
  52. Design, Synthesis, and Activity of Analogues of Phosphinothricin as Inhibitors of Glutamine Synthetase
  53. Herbicidal Pyridyl Derivatives of Aminomethylene-bisphosphonic Acid Inhibit Plant Glutamine Synthetase
  54. Cyclodextrins as NMR probes in the study of the enantiomeric compositions of N-benzyloxycarbonylamino-phosphonic and phosphinic acids
  55. Enantiodifferentiation of aminophosphonic and aminophosphinic acids with α- and β-cyclodextrins
  56. The use of molecular modelling for comparison of three possible modes of action of herbicidally active derivatives of aminomethylenebisphosphonic acid
  57. From Inhibitors of Lap to Inhibitors of Pal