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  1. 27th Annual GP2A Medicinal Chemistry Conference

    Article • Pharmaceuticals, December 2019, MDPI AG

    Dr Shailesh Natvarbhai Mistry

  2. Structure–Kinetic Profiling of Haloperidol Analogues at the Human Dopamine D2 Receptor

    Article • Journal of Medicinal Chemistry, October 2019, American Chemical Society (ACS)

    Dr Shailesh Natvarbhai Mistry

  3. A Thieno[2,3-d]pyrimidine Scaffold Is a Novel Negative Allosteric Modulator of the Dopamine D2 Receptor

    Article • Journal of Medicinal Chemistry, May 2018, American Chemical Society (ACS)

    Dr Shailesh Natvarbhai Mistry

  4. Novel selective β1-adrenoceptor antagonists for concomitant cardiovascular and respiratory disease

    Article • The FASEB Journal, July 2017, Federation of American Societies For Experimental Biology (FASEB)

    Jeanette Woolard, Dr Shailesh Natvarbhai Mistry, Gopal Jadhav

  5. New strategy to improve the current antipsychotics for treating symptoms of schizophrenia

    Article • Journal of Pharmacology and Experimental Therapeutics, September 2016, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Shailesh Natvarbhai Mistry, Dr Kwok Ho Christopher Choy

  6. GPCRs through the keyhole: the role of protein flexibility in ligand binding to β-adrenoceptors

    Article • Journal of Biomolecular Structure and Dynamics, September 2016, Taylor & Francis

    Dr Shailesh Natvarbhai Mistry

  7. Novel Fused Arylpyrimidinone Based Allosteric Modulators of the M1 Muscarinic Acetylcholine Receptor

    Article • ACS Chemical Neuroscience, March 2016, American Chemical Society (ACS)

    Dr Shailesh Natvarbhai Mistry

  8. Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions

    Article • European Journal of Medicinal Chemistry, March 2016, Elsevier

    Dr Shailesh Natvarbhai Mistry

  9. 4-Phenylpyridin-2-one Derivatives: A Novel Class of Positive Allosteric Modulator of the M1 Muscarinic Acetylcholine Receptor

    Article • Journal of Medicinal Chemistry, December 2015, American Chemical Society (ACS)

    Dr Shailesh Natvarbhai Mistry

  10. Discovery of a Novel Class of Negative Allosteric Modulator of the Dopamine D2 Receptor Through Fragmentation of a Bitopic Ligand

    Article • Journal of Medicinal Chemistry, August 2015, American Chemical Society (ACS)

    Dr Shailesh Natvarbhai Mistry

  11. Structure–Activity Study of N-((trans)-4-(2-(7-Cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)-1H-indole-2-carboxamide (SB269652), a Bitopic Ligand That Acts as a Negative Allosteric Modulator of the Dopamine D2 Receptor

    Article • Journal of Medicinal Chemistry, June 2015, American Chemical Society (ACS)

    Dr Shailesh Natvarbhai Mistry

  12. Screening the Medicines for Malaria Venture "Malaria Box" against the Plasmodium falciparum Aminopeptidases, M1, M17 and M18

    Article • PLoS ONE, February 2015, PLOS

    Dr Shailesh Natvarbhai Mistry

  13. Biased allosteric modulation at the CaS receptor engendered by structurally diverse calcimimetics

    Article • British Journal of Pharmacology, December 2014, Wiley

    Dr Sebastian George Barton Furness, Dr Shailesh Natvarbhai Mistry

  14. Two-Pronged Attack: Dual Inhibition of Plasmodium falciparum M1 and M17 Metalloaminopeptidases by a Novel Series of Hydroxamic Acid-Based Inhibitors

    Article • Journal of Medicinal Chemistry, October 2014, American Chemical Society (ACS)

    Dr Shailesh Natvarbhai Mistry

  15. Mechanistic Insights into Allosteric Structure-Function Relationships at the M1Muscarinic Acetylcholine Receptor

    Article • Journal of Biological Chemistry, October 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Shailesh Natvarbhai Mistry

  16. Triphenylphosphonium Anhydride Trifluoromethanesulfonate

    Article • May 2014, Wiley

    Dr Shailesh Natvarbhai Mistry

  17. Molecular Determinants of Allosteric Modulation at the M1Muscarinic Acetylcholine Receptor

    Article • Journal of Biological Chemistry, January 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Shailesh Natvarbhai Mistry

  18. Synthesis and Pharmacological Profiling of Analogues of Benzyl Quinolone Carboxylic Acid (BQCA) as Allosteric Modulators of the M1 Muscarinic Receptor

    Article • Journal of Medicinal Chemistry, June 2013, American Chemical Society (ACS)

    Dr Shailesh Natvarbhai Mistry

  19. Synthesis and in Vitro and in Vivo Characterization of Highly β1-Selective β-Adrenoceptor Partial Agonists

    Article • Journal of Medicinal Chemistry, May 2013, American Chemical Society (ACS)

    Dr Shailesh Natvarbhai Mistry

  20. 4,5-Dihydro-1-[(1S)-1-(hydroxymethyl)-2,2-dimethylpropyl]-3-(2,4,6-trimethylphenyl)-1H-imidazolium Hexafluorophosphate

    Article • September 2012, Wiley

    Dr Shailesh Natvarbhai Mistry

  21. Synthesis and Characterization of High-Affinity 4,4-Difluoro-4-bora-3a,4a-diaza-s-indacene-Labeled Fluorescent Ligands for Human β-Adrenoceptors

    Article • Journal of Medicinal Chemistry, October 2011, American Chemical Society (ACS)

    Dr Shailesh Natvarbhai Mistry

  22. Triphenylphosphonium Anhydride Trifluoromethanesulfonate

    Article • September 2011, Wiley

    Dr Shailesh Natvarbhai Mistry