Dr Shailesh Natvarbhai Mistry

  • University of Nottingham
  • United Kingdom

My co-authors include

Dr Kwok Ho Christopher Choy
Dr Sebastian George Barton Furness
Gopal Jadhav

My Publications

27th Annual GP2A Medicinal Chemistry Conference

  • Pharmaceuticals
  • December 2019

Structure–Kinetic Profiling of Haloperidol Analogues at the Human Dopamine D2 Receptor

  • Journal of Medicinal Chemistry
  • October 2019

A Thieno[2,3-d]pyrimidine Scaffold Is a Novel Negative Allosteric Modulator of the Dopa...

  • Journal of Medicinal Chemistry
  • May 2018

Novel selective β1-adrenoceptor antagonists for concomitant cardiovascular and respirat...

  • The FASEB Journal
  • July 2017

New strategy to improve the current antipsychotics for treating symptoms of schizophrenia

  • Journal of Pharmacology and Experimental Therapeutics
  • September 2016

GPCRs through the keyhole: the role of protein flexibility in ligand binding to β-adren...

  • Journal of Biomolecular Structure and Dynamics
  • September 2016

Novel Fused Arylpyrimidinone Based Allosteric Modulators of the M1 Muscarinic Acetylcho...

  • ACS Chemical Neuroscience
  • March 2016

Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through opti...

  • European Journal of Medicinal Chemistry
  • March 2016

4-Phenylpyridin-2-one Derivatives: A Novel Class of Positive Allosteric Modulator of th...

  • Journal of Medicinal Chemistry
  • December 2015

Discovery of a Novel Class of Negative Allosteric Modulator of the Dopamine D2 Receptor...

  • Journal of Medicinal Chemistry
  • August 2015

Structure–Activity Study of N-((trans)-4-(2-(7-Cyano-3,4-dihydroisoquinolin-2(1H)-yl)et...

  • Journal of Medicinal Chemistry
  • June 2015

Screening the Medicines for Malaria Venture "Malaria Box" against the Plasmodium falcip...

  • PLoS ONE
  • February 2015

Biased allosteric modulation at the CaS receptor engendered by structurally diverse cal...

  • British Journal of Pharmacology
  • December 2014

Two-Pronged Attack: Dual Inhibition of Plasmodium falciparum M1 and M17 Metalloaminopep...

  • Journal of Medicinal Chemistry
  • October 2014

Mechanistic Insights into Allosteric Structure-Function Relationships at the M1Muscarin...

  • Journal of Biological Chemistry
  • October 2014

Triphenylphosphonium Anhydride Trifluoromethanesulfonate

  • May 2014

Molecular Determinants of Allosteric Modulation at the M1Muscarinic Acetylcholine Receptor

  • Journal of Biological Chemistry
  • January 2014

Synthesis and Pharmacological Profiling of Analogues of Benzyl Quinolone Carboxylic Aci...

  • Journal of Medicinal Chemistry
  • June 2013

Synthesis and in Vitro and in Vivo Characterization of Highly β1-Selective β-Adrenocept...

  • Journal of Medicinal Chemistry
  • May 2013

4,5-Dihydro-1-[(1S)-1-(hydroxymethyl)-2,2-dimethylpropyl]-3-(2,4,6-trimethylphenyl)-1H-...

  • September 2012

Synthesis and Characterization of High-Affinity 4,4-Difluoro-4-bora-3a,4a-diaza-s-indac...

  • Journal of Medicinal Chemistry
  • October 2011

Triphenylphosphonium Anhydride Trifluoromethanesulfonate

  • September 2011