All Stories

  1. Design, synthesis and evaluation of novel 2-phenyl-3-(1H-pyrazol-4-yl)pyridine positive allosteric modulators for the M4 mAChR

    Article • European Journal of Medicinal Chemistry, October 2023, Elsevier

    Dr Kwok Ho Christopher Choy

  2. Blockade of Microglial Kv1.3 Potassium Channels by the Peptide HsTX1[R14A] Attenuates Lipopolysaccharide-mediated Neuroinflammation

    Article • Journal of Pharmaceutical Sciences, March 2022, Elsevier

    Dr Kwok Ho Christopher Choy

  3. Cognitive behavioral markers of neurodevelopmental trajectories in rodents

    Article • Translational Psychiatry, October 2021, Springer Science + Business Media

    Dr Kwok Ho Christopher Choy

  4. Fine Tuning Muscarinic Acetylcholine Receptor Signaling Through Allostery and Bias

    Article • Frontiers in Pharmacology, January 2021, Frontiers

    Dr Kwok Ho Christopher Choy

  5. Neurological, neuropsychiatric and neurodevelopmental complications of COVID-19

    Article • Australian & New Zealand Journal of Psychiatry, October 2020, SAGE Publications

    Dr Kwok Ho Christopher Choy

  6. Development of Novel 4‐Arylpyridin‐2‐one and 6‐Arylpyrimidin‐4‐one Positive Allosteric Modulators of the M 1 Muscarinic Acetylcholine Receptor

    Article • ChemMedChem, September 2020, Wiley

    Dr Kwok Ho Christopher Choy

  7. The effect of angiotensin AT1A inactivation on innate and learned fear responses in mice and its relationship to blood pressure

    Article • Psychoneuroendocrinology, September 2019, Elsevier

    Dr Kwok Ho Christopher Choy

  8. 6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity

    Article • ACS Chemical Neuroscience, December 2018, American Chemical Society (ACS)

    Dr Kwok Ho Christopher Choy

  9. Cognitive benefits of lithium chloride in APP/PS1 mice are associated with enhanced brain clearance of β-amyloid

    Article • Brain Behavior and Immunity, May 2018, Elsevier

    Dr Kwok Ho Christopher Choy

  10. Reduced blood-brain barrier expression of fatty acid-binding protein 5 is associated with increased vulnerability of APP/PS1 mice to cognitive deficits from low omega-3 fatty acid diets

    Article • Journal of Neurochemistry, December 2017, Wiley

    Professor Philip John Marriott, Dr Kwok Ho Christopher Choy, Christopher Porter

  11. Fatty Acid-Binding Protein 5 at the Blood–Brain Barrier Regulates Endogenous Brain Docosahexaenoic Acid Levels and Cognitive Function

    Article • Journal of Neuroscience, November 2016, Society for Neuroscience

    Christopher Porter, Professor Martin J Scanlon, Dr Kwok Ho Christopher Choy

  12. New strategy to improve the current antipsychotics for treating symptoms of schizophrenia

    Article • Journal of Pharmacology and Experimental Therapeutics, September 2016, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Shailesh Natvarbhai Mistry, Dr Kwok Ho Christopher Choy

  13. Allosteric Modulation of M1Muscarinic Acetylcholine Receptor Internalization and Subcellular Trafficking

    Article • Journal of Biological Chemistry, April 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Kwok Ho Christopher Choy

  14. Long-term behavioral and NMDA receptor effects of young-adult corticosterone treatment in BDNF heterozygous mice

    Article • Neurobiology of Disease, June 2012, Elsevier

    Dr Kwok Ho Christopher Choy

  15. Analysis of vigilant scanning behavior in mice using two-point digital video tracking

    Article • Psychopharmacology, December 2011, Springer Science + Business Media

    Dr Kwok Ho Christopher Choy

  16. Effects of N-acetyl-cysteine treatment on glutathione depletion and a short-term spatial memory deficit in 2-cyclohexene-1-one-treated rats

    Article • European Journal of Pharmacology, December 2010, Elsevier

    Dr Kwok Ho Christopher Choy

  17. The effect of ‘two hit’ neonatal and young-adult stress on dopaminergic modulation of prepulse inhibition and dopamine receptor density

    Article • British Journal of Pharmacology, January 2009, Wiley

    Dr Kwok Ho Christopher Choy

  18. Combined neonatal stress and young‐adult glucocorticoid stimulation in rats reduce BDNF expression in hippocampus: Effects on learning and memory

    Article • Hippocampus, July 2008, Wiley

    Dr Kwok Ho Christopher Choy

  19. Attenuated disruption of prepulse inhibition by dopaminergic stimulation after maternal deprivation and adolescent corticosterone treatment in rats

    Article • European Neuropsychopharmacology, January 2008, Elsevier

    Dr Kwok Ho Christopher Choy