All Stories

  1. Effects of Gestational Exercise on Nociception, BDNF, and Irisin Levels in an Animal Model of ADHD

    Article • Neuroscience, April 2024, Elsevier

    Sergio Ferreira

  2. Effects of sex and gestational exercise on pain perception, BDNF and irisin levels in an animal model of ADHD

    Article • August 2023, Cold Spring Harbor Laboratory Press

    Sergio Ferreira

  3. Defective proteostasis in Alzheimer’s disease

    Article • Ageing Research Reviews, March 2023, Elsevier

    Sergio Ferreira

  4. Purinergic signaling in cognitive impairment and neuropsychiatric symptoms of Alzheimer's disease

    Article • Neuropharmacology, March 2023, Elsevier

    Sergio Ferreira

  5. AAV-mediated neuronal expression of an scFv antibody selective for Aβ oligomers protects synapses and rescues memory in Alzheimer models

    Article • Molecular Therapy, February 2023, Elsevier

    Sergio Ferreira

  6. Brain FNDC5/Irisin Expression in Patients and Mouse Models of Major Depression

    Article • eNeuro, January 2023, Society for Neuroscience

    Sergio Ferreira

  7. Lung inflammation induced by silica particles triggers hippocampal inflammation, synapse damage and memory impairment in mice

    Article • Journal of Neuroinflammation, December 2022, Springer Science + Business Media

    Sergio Ferreira

  8. Cerebrospinal fluid irisin and lipoxin A4 are reduced in elderly Brazilian individuals with depression: Insight into shared mechanisms between depression and dementia

    Article • Alzheimer s & Dementia, December 2022, Wiley

    Sergio Ferreira

  9. Age-linked suppression of lipoxin A4 associates with cognitive deficits in mice and humans

    Article • Translational Psychiatry, October 2022, Springer Science + Business Media

    Fabricio Pamplona, Sergio Ferreira

  10. Biomarkers for dementia in Latin American countries: Gaps and opportunities

    Article • Alzheimer s & Dementia, September 2022, Wiley

    Dr Agustin Ibanez, Sergio Ferreira

  11. Irisin stimulates protective signaling pathways in rat hippocampal neurons

    Article • Frontiers in Cellular Neuroscience, September 2022, Frontiers

    Sergio Ferreira

  12. Uncovering bidirectional brain-body interactions in health and disease

    Article • Neuropharmacology, July 2022, Elsevier

    Sergio Ferreira

  13. The unfolded protein response transcription factor XBP1s ameliorates Alzheimer’s disease by improving synaptic function and proteostasis

    Article • June 2022, Cold Spring Harbor Laboratory Press

    Sergio Ferreira

  14. AAV-mediated neuronal expression of a scFv antibody selective for Aβ oligomers protects synapses and rescues memory in Alzheimer models

    Article • June 2022, Cold Spring Harbor Laboratory Press

    Sergio Ferreira

  15. Oxytocin attenuates microglial activation and restores social and non-social memory in the APP/PS1 mouse model of Alzheimer’s disease

    Article • May 2022, Cold Spring Harbor Laboratory Press

    Sergio Ferreira

  16. Inflammation at the crossroads of COVID-19, cognitive deficits and depression

    Article • Neuropharmacology, May 2022, Elsevier

    Sergio Ferreira

  17. Impaired insulin signalling and allostatic load in Alzheimer disease

    Article • Nature Reviews Neuroscience, February 2022, Springer Science + Business Media

    Sergio Ferreira

  18. Age-linked suppression of lipoxin A4 mediates cognitive deficits in mice and humans

    Article • November 2021, Cold Spring Harbor Laboratory Press

    Sergio Ferreira

  19. A Specialized Nutritional Formulation Prevents Hippocampal Glial Activation and Memory Impairment Induced by Amyloid-β Oligomers in Mice

    Article • Journal of Alzheimer’s Disease, September 2021, IOS Press

    Sergio Ferreira

  20. Cerebrospinal Fluid Neurotransmitters, Cytokines, and Chemokines in Alzheimer’s and Lewy Body Diseases

    Article • Journal of Alzheimer’s Disease, August 2021, IOS Press

    Sergio Ferreira

  21. Innate immune memory mediates increased susceptibility to Alzheimer’s disease-like pathology in sepsis surviving mice

    Article • Brain Behavior and Immunity, July 2021, Elsevier

    Sergio Ferreira

  22. Selective Secretase Targeting for Alzheimer’s Disease Therapy

    Article • Journal of Alzheimer’s Disease, May 2021, IOS Press

    Sergio Ferreira

  23. Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer’s disease

    Article • Translational Psychiatry, April 2021, Springer Science + Business Media

    Sergio Ferreira

  24. Dementia is an age‐independent risk factor for severity and death in COVID‐19 inpatients

    Article • Alzheimer s & Dementia, April 2021, Wiley

    Sergio Ferreira

  25. Rapid size-exclusion high performance liquid chromatography method for the quality control of amyloid-β oligomers

    Article • Journal of Chromatography A, April 2021, Elsevier

    Sergio Ferreira

  26. Brain insulin, insulin‐like growth factor 1 and glucagon‐like peptide 1 signalling in Alzheimer’s disease

    Article • Journal of Neuroendocrinology, March 2021, Wiley

    Sergio Ferreira

  27. Interleukin-1β mediates alterations in mitochondrial fusion/fission proteins and memory impairment induced by amyloid-β oligomers

    Article • Journal of Neuroinflammation, February 2021, Springer Science + Business Media

    Sergio Ferreira

  28. Correction of eIF2-dependent defects in brain protein synthesis, synaptic plasticity, and memory in mouse models of Alzheimer’s disease

    Article • Science Signaling, February 2021, American Association for the Advancement of Science

    Sergio Ferreira

  29. Dementia in Latin America: Paving the way toward a regional action plan

    Article • Alzheimer s & Dementia, November 2020, Wiley

    Dr Fabricio Ferreira de Oliveira, Adolfo M. García, Dr Agustin Ibanez, Sergio Ferreira, Dominic Trépel

  30. Correction of eIF2-dependent defects in brain protein synthesis, synaptic plasticity and memory in mouse models of Alzheimer’s disease

    Article • October 2020, Cold Spring Harbor Laboratory Press

    Sergio Ferreira

  31. Erratum: Forny-Germano et al., “Alzheimer's Disease-Like Pathology Induced by Amyloid-β Oligomers in Nonhuman Primates”

    Article • Journal of Neuroscience, October 2020, Society for Neuroscience

    Sergio Ferreira

  32. Correction: Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice

    Article • Molecular Psychiatry, September 2020, Springer Science + Business Media

    Sergio Ferreira

  33. Roles of glutamate receptors in a novel in vitro model of early, comorbid cerebrovascular, and Alzheimer’s diseases

    Article • Journal of Neurochemistry, August 2020, Wiley

    Sergio Ferreira

  34. The aroylhydrazone INHHQ prevents memory impairment induced by Alzheimer’s-linked amyloid-β oligomers in mice

    Article • Behavioural Pharmacology, August 2020, Wolters Kluwer Health

    Sergio Ferreira

  35. Insulin and leptin as potential cognitive enhancers in metabolic disorders and Alzheimer's disease

    Article • Neuropharmacology, July 2020, Elsevier

    Sergio Ferreira

  36. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and the Central Nervous System

    Article • Trends in Neurosciences, June 2020, Elsevier

    Sergio Ferreira

  37. Amyloid‐β oligomers in cellular models of Alzheimer’s disease

    Article • Journal of Neurochemistry, May 2020, Wiley

    Sergio Ferreira

  38. Amyloid-β Fosters p35/CDK5 Signaling Contributing to Changes of Inhibitory Synapses in Early Stages of Cerebral Amyloidosis

    Article • Journal of Alzheimer’s Disease, April 2020, IOS Press

    Sergio Ferreira

  39. Morphometric Analysis of Hippocampal and Neocortical Pyramidal Neurons in a Mouse Model of Late Onset Alzheimer’s Disease

    Article • Journal of Alzheimer’s Disease, April 2020, IOS Press

    Sergio Ferreira

  40. Modulation in phase and frequency of neural oscillations during epileptiform activity induced by neonatal Zika virus infection in mice

    Article • Scientific Reports, April 2020, Springer Science + Business Media

    Sergio Ferreira

  41. Palmitate Is Increased in the Cerebrospinal Fluid of Humans with Obesity and Induces Memory Impairment in Mice via Pro-inflammatory TNF-α

    Article • Cell Reports, February 2020, Elsevier

    Sergio Ferreira

  42. LDL Receptor Deficiency Does not Alter Brain Amyloid-β Levels but Causes an Exacerbation of Apoptosis

    Article • Journal of Alzheimer’s Disease, January 2020, IOS Press

    Sergio Ferreira

  43. Cerebrospinal fluid irisin correlates with amyloid‐β, BDNF, and cognition in Alzheimer's disease

    Article • Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring, January 2020, Wiley

    Sergio Ferreira

  44. Adenovirus-Mediated Transduction of Insulin-Like Growth Factor 1 Protects Hippocampal Neurons from the Toxicity of Aβ Oligomers and Prevents Memory Loss in an Alzheimer Mouse Model

    Article • Molecular Neurobiology, November 2019, Springer Science + Business Media

    Sergio Ferreira

  45. Extracellular vesicles derived from human Wharton’s jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers

    Article • Stem Cell Research & Therapy, November 2019, Springer Science + Business Media

    Sergio Ferreira

  46. Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice

    Article • Nature Communications, September 2019, Springer Science + Business Media

    Sergio Ferreira

  47. Using a portable total reflection X‐ray fluorescence system for a multielement analysis of Swiss mice brains with experimental Alzheimer's disease induced by β‐amyloid oligomers

    Article • X-Ray Spectrometry, April 2019, Wiley

    Sergio Ferreira

  48. Neonatal infection leads to increased susceptibility to Aβ oligomer-induced brain inflammation, synapse loss and cognitive impairment in mice

    Article • Cell Death and Disease, April 2019, Springer Science + Business Media

    Sergio Ferreira

  49. Diet-Derived Fatty Acids, Brain Inflammation, and Mental Health

    Article • Frontiers in Neuroscience, March 2019, Frontiers

    Sergio Ferreira

  50. Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

    Article • Nature Reports Stem Cells, January 2019, Springer Science + Business Media

    Sergio Ferreira

  51. Mania-like elevated mood in rats: Enhanced 50-kHz ultrasonic vocalizations after sleep deprivation

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, January 2019, Elsevier

    Sergio Ferreira

  52. Blood Levels of Glutamate and Glutamine in Recent Onset and Chronic Schizophrenia

    Article • Frontiers in Psychiatry, December 2018, Frontiers

    Sergio Ferreira

  53. Neuroprotective Actions of Glucagon-Like Peptide-1 (GLP-1) Analogues in Alzheimer’s and Parkinson’s Diseases

    Article • CNS Drugs, December 2018, Springer Science + Business Media

    Sergio Ferreira

  54. Elevated Glutamate and Glutamine Levels in the Cerebrospinal Fluid of Patients With Probable Alzheimer's Disease and Depression

    Article • Frontiers in Psychiatry, November 2018, Frontiers

    Sergio Ferreira

  55. Free-floating adult human brain-derived slice cultures as a model to study the neuronal impact of Alzheimer’s disease-associated Aβ oligomers

    Article • Journal of Neuroscience Methods, September 2018, Elsevier

    Sergio Ferreira

  56. Are Alzheimer's disease and other neurodegenerative disorders caused by impaired signalling of insulin and other hormones?

    Article • Neuropharmacology, July 2018, Elsevier

    christian Holscher, Sergio Ferreira

  57. Crosstalk between endoplasmic reticulum stress and brain inflammation in Alzheimer's disease

    Article • Neuropharmacology, July 2018, Elsevier

    Sergio Ferreira

  58. Brain Inflammation Connects Cognitive and Non-Cognitive Symptoms in Alzheimer’s Disease

    Article • Journal of Alzheimer’s Disease, June 2018, IOS Press

    Sergio Ferreira

  59. Acute and chronic neurological consequences of early-life Zika virus infection in mice

    Article • Science Translational Medicine, June 2018, American Association for the Advancement of Science

    Sergio Ferreira

  60. The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimer's disease

    Article • The Journal of Pathology, April 2018, Wiley

    André Felipe Batista, christian Holscher, Sergio Ferreira

  61. Mesenchymal stem cells and cell-derived extracellular vesicles protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers

    Article • Journal of Biological Chemistry, February 2018, Elsevier

    Sergio Ferreira

  62. Neuroprotective astrocyte-derived insulin/insulin-like growth factor 1 stimulates endocytic processing and extracellular release of neuron-bound Aβ oligomers

    Article • Molecular Biology of the Cell, October 2017, American Society for Cell Biology (ASCB)

    Sergio Ferreira

  63. Neonatal Zika virus infection causes epileptic seizures, viral persistence and long-term behavioral impairment

    Article • September 2017, Cold Spring Harbor Laboratory Press

    Sergio Ferreira

  64. A human scFv antibody that targets and neutralizes high molecular weight pathogenic amyloid-β oligomers

    Article • Journal of Neurochemistry, August 2017, Wiley

    Sergio Ferreira

  65. Brain infusion of α-synuclein oligomers induces motor and non-motor Parkinson’s disease-like symptoms in mice

    Article • Behavioural Brain Research, August 2017, Elsevier

    Sergio Ferreira

  66. Chronic sleep restriction promotes brain inflammation and synapse loss, and potentiates memory impairment induced by amyloid-β oligomers in mice

    Article • Brain Behavior and Immunity, August 2017, Elsevier

    Sergio Ferreira

  67. Astrocyte Transforming Growth Factor Beta 1 Protects Synapses against Aβ Oligomers in Alzheimer's Disease Model

    Article • Journal of Neuroscience, June 2017, Society for Neuroscience

    Sergio Ferreira

  68. Amyloid-β oligomers transiently inhibit AMP-activated kinase and cause metabolic defects in hippocampal neurons

    Article • Journal of Biological Chemistry, March 2017, Elsevier

    Wagner Seixas da-Silva, Sergio Ferreira

  69. Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice

    Article • Journal of Biological Chemistry, March 2017, Elsevier

    Sergio Ferreira

  70. Multielement concentration analysis of Swiss mice brains on experimental model of Alzheimer's disease induced byβ-amyloid oligomers

    Article • X-Ray Spectrometry, February 2017, Wiley

    Professor Ricardo Tadeu Lopes, Sergio Ferreira

  71. Protein Tyrosine Phosphatase 1B (PTP1B): A Potential Target for Alzheimer’s Therapy?

    Article • Frontiers in Aging Neuroscience, January 2017, Frontiers

    Sergio Ferreira

  72. Diazepam Inhibits Electrically Evoked and Tonic Dopamine Release in the Nucleus Accumbens and Reverses the Effect of Amphetamine

    Article • ACS Chemical Neuroscience, January 2017, American Chemical Society (ACS)

    Sergio Ferreira

  73. Brain-Defective Insulin Signaling Is Associated to Late Cognitive Impairment in Post-Septic Mice

    Article • Molecular Neurobiology, December 2016, Springer Science + Business Media

    Sergio Ferreira

  74. Getting a “GRiP” on Hypothalamic Endoplasmic Reticulum Stress to Combat Obesity

    Article • Diabetes, December 2016, American Diabetes Association

    Sergio Ferreira

  75. Cross Talk Between Brain Innate Immunity and Serotonin Signaling Underlies Depressive-Like Behavior Induced by Alzheimer's Amyloid-β Oligomers in Mice

    Article • Journal of Neuroscience, November 2016, Society for Neuroscience

    Sergio Ferreira

  76. Microglial dysfunction connects depression and Alzheimer’s disease

    Article • Brain Behavior and Immunity, July 2016, Elsevier

    Sergio Ferreira

  77. USP46: a new piece of the memory puzzle?

    Article • Journal of Neurochemistry, August 2015, Wiley

    Sergio Ferreira

  78. Neuronal stress signaling and eIF2α phosphorylation as molecular links between Alzheimer's disease and diabetes

    Article • Progress in Neurobiology, June 2015, Elsevier

    Sergio Ferreira

  79. Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer’s disease

    Article • Frontiers in Cellular Neuroscience, May 2015, Frontiers

    Sergio Ferreira

  80. d-serine levels in Alzheimer’s disease: implications for novel biomarker development

    Article • Translational Psychiatry, May 2015, Springer Science + Business Media

    Sergio Ferreira

  81. Mitomycin-treated undifferentiated embryonic stem cells as a safe and effective therapeutic strategy in a mouse model of Parkinson’s disease

    Article • Frontiers in Cellular Neuroscience, April 2015, Frontiers

    Sergio Ferreira

  82. Alzheimer-associated A  oligomers impact the central nervous system to induce peripheral metabolic deregulation

    Article • EMBO Molecular Medicine, January 2015, EMBO

    Sergio Ferreira

  83. Alzheimer's Disease-Like Pathology Induced by Amyloid-β Oligomers in Nonhuman Primates

    Article • Journal of Neuroscience, October 2014, Society for Neuroscience

    Sergio Ferreira

  84. Inflammation, Defective Insulin Signaling, and Mitochondrial Dysfunction as Common Molecular Denominators Connecting Type 2 Diabetes to Alzheimer Disease

    Article • Diabetes, June 2014, American Diabetes Association

    Sergio Ferreira

  85. Accumulation of Intraneuronal Amyloid-β is Common in Normal Brain

    Article • Current Alzheimer Research, April 2014, Bentham Science Publishers

    Professor George Perry, Sergio Ferreira

  86. How does brain insulin resistance develop in Alzheimer's disease?

    Article • Alzheimer s & Dementia, February 2014, Wiley

    Sergio Ferreira

  87. Inflammation, defective insulin signaling, and neuronal dysfunction in Alzheimer's disease

    Article • Alzheimer s & Dementia, February 2014, Wiley

    Sergio Ferreira

  88. TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and Monkeys

    Article • Cell Metabolism, December 2013, Elsevier

    christian Holscher, Sergio Ferreira

  89. 2,4-dinitrophenol induces neural differentiation of murine embryonic stem cells

    Article • Stem Cell Research, November 2013, Elsevier

    Sergio Ferreira

  90. The Prion Protein Ligand, Stress-Inducible Phosphoprotein 1, Regulates Amyloid-β Oligomer Toxicity

    Article • Journal of Neuroscience, October 2013, Society for Neuroscience

    Sergio Ferreira

  91. Activated microglia mediate synapse loss and short-term memory deficits in a mouse model of transthyretin-related oculoleptomeningeal amyloidosis

    Article • Cell Death and Disease, September 2013, Springer Science + Business Media

    Sergio Ferreira

  92. Amyloid-β oligomers induce tau-independent disruption of BDNF axonal transport via calcineurin activation in cultured hippocampal neurons

    Article • Molecular Biology of the Cell, August 2013, American Society for Cell Biology (ASCB)

    Sergio Ferreira

  93. Rescue of Amyloid-Beta-Induced Inhibition of Nicotinic Acetylcholine Receptors by a Peptide Homologous to the Nicotine Binding Domain of the Alpha 7 Subtype

    Article • PLOS One, July 2013, PLOS

    Sergio Ferreira

  94. α-Secretase-derived fragment of cellular prion, N1, protects against monomeric and oligomeric amyloid β (Aβ)-associated cell death.

    Article • Journal of Biological Chemistry, July 2013, Elsevier

    Sergio Ferreira

  95. Memantine Rescues Transient Cognitive Impairment Caused by High-Molecular-Weight A  Oligomers But Not the Persistent Impairment Induced by Low-Molecular-Weight Oligomers

    Article • Journal of Neuroscience, June 2013, Society for Neuroscience

    Sergio Ferreira

  96. Deregulation of excitatory neurotransmission underlying synapse failure in Alzheimer's disease

    Article • Journal of Neurochemistry, May 2013, Wiley

    Sergio Ferreira, Andrea Paula-Lima

  97. Plasma levels of D-serine in Brazilian individuals with schizophrenia

    Article • Schizophrenia Research, December 2012, Elsevier

    Sergio Ferreira

  98. Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice

    Article • Molecular Psychiatry, November 2012, Springer Science + Business Media

    Sergio Ferreira

  99. Human Apolipoprotein A-I Natural Variants: Molecular Mechanisms Underlying Amyloidogenic Propensity

    Article • PLOS One, August 2012, PLOS

    Sergio Ferreira

  100. Inhibition of Choline Acetyltransferase as a Mechanism for Cholinergic Dysfunction Induced by Amyloid-β Peptide Oligomers

    Article • Journal of Biological Chemistry, June 2012, Elsevier

    Sergio Ferreira

  101. An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers

    Article • Journal of Clinical Investigation, April 2012, American Society for Clinical Investigation

    christian Holscher, Sergio Ferreira

  102. Amyloid-β Oligomers Induce Differential Gene Expression in Adult Human Brain Slices

    Article • Journal of Biological Chemistry, March 2012, Elsevier

    Sergio Ferreira, Andrea Paula-Lima

  103. α-Secretase-derived Fragment of Cellular Prion, N1, Protects against Monomeric and Oligomeric Amyloid β (Aβ)-associated Cell Death

    Article • Journal of Biological Chemistry, February 2012, Elsevier

    Sergio Ferreira

  104. The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease

    Article • Neurobiology of Learning and Memory, November 2011, Elsevier

    Sergio Ferreira

  105. Aβ Oligomers Induce Glutamate Release from Hippocampal Neurons

    Article • Current Alzheimer Research, August 2011, Bentham Science Publishers

    Sergio Ferreira, Andrea Paula-Lima

  106. Human Apolipoprotein A-I-Derived Amyloid: Its Association with Atherosclerosis

    Article • PLOS One, July 2011, PLOS

    Sergio Ferreira

  107. Amyloid β-Peptide Oligomers Stimulate RyR-Mediated Ca2+ Release Inducing Mitochondrial Fragmentation in Hippocampal Neurons and Prevent RyR-Mediated Dendritic Spine Remodeling Produced by BDNF

    Article • Antioxidants & Redox Signaling, April 2011, Mary Ann Liebert Inc

    Sergio Ferreira, Andrea Paula-Lima

  108. Amyloid-beta oligomers increase the localization of prion protein at the cell surface

    Article • Journal of Neurochemistry, March 2011, Wiley

    Professor Marco A M Prado, Dr Andre Luiz Sena Guimaraes, Sergio Ferreira

  109. Activation of D1/D5 Dopamine Receptors Protects Neurons from Synapse Dysfunction Induced by Amyloid-β Oligomers

    Article • Journal of Biological Chemistry, February 2011, Elsevier

    Sergio Ferreira

  110. Amyloid-β Triggers the Release of Neuronal Hexokinase 1 from Mitochondria

    Article • PLOS One, December 2010, PLOS

    Wagner Seixas da-Silva, Sergio Ferreira

  111. Protein kinase C activity regulates d-serine availability in the brain

    Article • Journal of Neurochemistry, December 2010, Wiley

    Sergio Ferreira

  112. N‐Methyl‐d‐aspartate receptors are required for synaptic targeting of Alzheimer’s toxic amyloid‐β peptide oligomers

    Article • Journal of Neurochemistry, November 2010, Wiley

    Sergio Ferreira

  113. Amyloid-β Decreases Nitric Oxide Production in Cultured Retinal Neurons: A Possible Mechanism for Synaptic Dysfunction in Alzheimer’s Disease?

    Article • Neurochemical Research, October 2010, Springer Science + Business Media

    Sergio Ferreira

  114. Amyloid-  Peptide Oligomers Disrupt Axonal Transport through an NMDA Receptor-Dependent Mechanism That Is Mediated by Glycogen Synthase Kinase 3  in Primary Cultured Hippocampal Neurons

    Article • Journal of Neuroscience, July 2010, Society for Neuroscience

    Sergio Ferreira

  115. 2,4-Dinitrophenol Blocks Neurodegeneration and Preserves Sciatic Nerve Function after Trauma

    Article • Journal of Neurotrauma, May 2010, Mary Ann Liebert Inc

    Sergio Ferreira

  116. Expression Profile of Rat Hippocampal Neurons Treated with the Neuroprotective Compound 2,4-Dinitrophenol: Up-Regulation of cAMP Signaling Genes

    Article • Neurotoxicity Research, December 2009, Springer Science + Business Media

    Sergio Ferreira

  117. Conformational plasticity of DM43, a metalloproteinase inhibitor from Didelphis marsupialis: Chemical and pressure-induced equilibrium (un)folding studies

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, October 2009, Elsevier

    Sergio Ferreira

  118. Nicotinic Receptors, Amyloid-β, and Synaptic Failure in Alzheimer’s Disease

    Article • Journal of Molecular Neuroscience, August 2009, Springer Science + Business Media

    Sergio Ferreira

  119. Human apolipoprotein A–I binds amyloid-β and prevents Aβ-induced neurotoxicity

    Article • The International Journal of Biochemistry & Cell Biology, June 2009, Elsevier

    Sergio Ferreira, Andrea Paula-Lima

  120. Correction for De Felice et al., Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers

    Article • Proceedings of the National Academy of Sciences, May 2009, Proceedings of the National Academy of Sciences

    Sergio Ferreira

  121. Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers

    Article • Proceedings of the National Academy of Sciences, February 2009, Proceedings of the National Academy of Sciences

    Sergio Ferreira

  122. Reductive inactivation of yeast glutathione reductase by Fe(II) and NADPH

    Article • Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology, November 2008, Elsevier

    Sergio Ferreira

  123. Amyloid-β Binds to the Extracellular Cysteine-rich Domain of Frizzled and Inhibits Wnt/β-Catenin Signaling

    Article • Journal of Biological Chemistry, April 2008, Elsevier

    Sergio Ferreira

  124. Interrogating global gene expression in rat neuronal cultures using SAGE

    Article • Neurotoxicity Research, December 2007, Springer Science + Business Media

    Sergio Ferreira

  125. Soluble oligomers from a non‐disease related protein mimic Aβ‐induced tau hyperphosphorylation and neurodegeneration

    Article • Journal of Neurochemistry, July 2007, Wiley

    Sergio Ferreira

  126. Cyclic AMP Enhancers and Aβ Oligomerization Blockers as Potential Therapeutic Agents in Alzheimers Disease

    Article • Current Alzheimer Research, July 2007, Bentham Science Publishers

    Sergio Ferreira

  127. Structure and functions of the human amyloid precursor protein: The whole is more than the sum of its parts

    Article • Progress in Neurobiology, May 2007, Elsevier

    Sergio Ferreira

  128. Aβ Oligomers Induce Neuronal Oxidative Stress through an N-Methyl-D-aspartate Receptor-dependent Mechanism That Is Blocked by the Alzheimer Drug Memantine

    Article • Journal of Biological Chemistry, April 2007, Elsevier

    Sergio Ferreira

  129. Whither Latin America? trends and challenges of science in Latin America

    Article • IUBMB Life, January 2007, Wiley

    Sergio Ferreira

  130. Soluble protein oligomers as emerging toxins in alzheimer's and other amyloid diseases

    Article • IUBMB Life, January 2007, Wiley

    Sergio Ferreira

  131. Quantitative histogram analysis of images

    Article • Computer Physics Communications, November 2006, Elsevier

    Sergio Ferreira

  132. Long-Lived Conformational Isomerism of Protein Dimers: The Role of the Free Energy of Subunit Association

    Article • Biophysical Journal, October 2006, Elsevier

    Sergio Ferreira

  133. Formation of Soluble Oligomers and Amyloid Fibrils with Physical Properties of the Scrapie Isoform of the Prion Protein from the C-terminal Domain of Recombinant Murine Prion Protein mPrP-(121–231)

    Article • Journal of Biological Chemistry, September 2006, Elsevier

    Sergio Ferreira

  134. Novel neuroprotective, neuritogenic and anti-amyloidogenic properties of 2,4-dinitrophenol: The gentle face of Janus

    Article • IUBMB Life, April 2006, Wiley

    Sergio Ferreira

  135. Solution Conformation and Heparin-induced Dimerization of the Full-length Extracellular Domain of the Human Amyloid Precursor Protein

    Article • Journal of Molecular Biology, March 2006, Elsevier

    Sergio Ferreira

  136. Metastable, Partially Folded States in the Productive Folding and in the Misfolding and Amyloid Aggregation of Proteins

    Article • Cell Biochemistry and Biophysics, January 2006, Springer Science + Business Media

    Sergio Ferreira

  137. Small Molecule Inhibitors of Lysozyme Amyloid Aggregation

    Article • Cell Biochemistry and Biophysics, January 2006, Springer Science + Business Media

    Sergio Ferreira

  138. Activation of GABAA receptors by taurine and muscimol blocks the neurotoxicity of β-amyloid in rat hippocampal and cortical neurons

    Article • Neuropharmacology, December 2005, Elsevier

    Sergio Ferreira, Andrea Paula-Lima

  139. Structural and morphological characterization of hemozoin produced by Schistosoma mansoni and Rhodnius prolixus

    Article • FEBS Letters, October 2005, Wiley

    Sergio Ferreira

  140. Neuritogenesis and neuronal differentiation promoted by 2,4‐dinitrophenol, a novel anti‐amyloidogenic compound

    Article • The FASEB Journal, October 2005, Wiley

    Sergio Ferreira

  141. Acid- and pressure-induced (un)folding of yeast glutathione reductase: Competition between protein oligomerization and aggregation

    Article • The International Journal of Biochemistry & Cell Biology, September 2005, Elsevier

    Sergio Ferreira

  142. Heparin-binding Sites in Granulocyte-Macrophage Colony-stimulating Factor

    Article • Journal of Biological Chemistry, September 2005, Elsevier

    Sergio Ferreira

  143. Peptide Blockers of the Inhibition of Neuronal Nicotinic Acetylcholine Receptors by Amyloid β

    Article • Journal of Biological Chemistry, September 2005, Elsevier

    Sergio Ferreira

  144. Folding and stability of a coiled-coil investigated using chemical and physical denaturing agents: Comparative analysis of polymerized and non-polymerized forms of α-tropomyosin

    Article • The International Journal of Biochemistry & Cell Biology, July 2005, Elsevier

    Sergio Ferreira

  145. Protein Folding, Misfolding and Aggregation: Evolving Concepts and Conformational Diseases

    Article • Protein and Peptide Letters, April 2005, Bentham Science Publishers

    Sergio Ferreira

  146. Amyloidogenicity and Cytotoxicity of Recombinant Mature Human Islet Amyloid Polypeptide (rhIAPP)

    Article • Journal of Biological Chemistry, October 2004, Elsevier

    Sergio Ferreira

  147. Biological evaluation of a protein isolate from cowpea (Vigna unguiculata) seeds

    Article • Food Chemistry, October 2004, Elsevier

    Sergio Ferreira

  148. Targeting the neurotoxic species in Alzheimer's disease: inhibitors of Aβ oligomerization

    Article • The FASEB Journal, September 2004, Wiley

    Sergio Ferreira

  149. Inhibition of Heme Aggregation by Chloroquine ReducesSchistosoma mansoniInfection

    Article • The Journal of Infectious Diseases, August 2004, Oxford University Press (OUP)

    Dr Antonio Ferreira-Pereira, Sergio Ferreira

  150. Formation of amyloid aggregates from human lysozyme and its disease‐associated variants using hydrostatic pressure

    Article • The FASEB Journal, May 2004, Wiley

    Sergio Ferreira

  151. Inhibition of yeast glutathione reductase by trehalose: possible implications in yeast survival and recovery from stress

    Article • The International Journal of Biochemistry & Cell Biology, May 2004, Elsevier

    Sergio Ferreira

  152. Taurine prevents the neurotoxicity of β‐amyloid and glutamate receptor agonists: activation of GABA receptors and possible implications for Alzheimer's disease and other neurological disorders

    Article • The FASEB Journal, March 2004, Wiley

    Sergio Ferreira, Andrea Paula-Lima

  153. Redesigning the Folding Energetics of a Model Three-helix Bundle Protein by Site-directed Mutagenesis

    Article • Journal of Biological Chemistry, March 2004, Elsevier

    Sergio Ferreira

  154. Closed Conformation of the Active Site Loop of Rabbit Muscle Triosephosphate Isomerase in the Absence of Substrate: Evidence of Conformational Heterogeneity

    Article • Journal of Molecular Biology, December 2003, Elsevier

    Sergio Ferreira

  155. Folding Intermediates of the Prion Protein Stabilized by Hydrostatic Pressure and Low Temperature

    Article • Journal of Biological Chemistry, December 2003, Elsevier

    Sergio Ferreira

  156. Persistent Conformational Heterogeneity of Triosephosphate Isomerase:  Separation and Characterization of Conformational Isomers in Solution

    Article • Biochemistry, November 2003, American Chemical Society (ACS)

    Sergio Ferreira

  157. Folding and Stability of the Extracellular Domain of the Human Amyloid Precursor Protein

    Article • Journal of Biological Chemistry, September 2003, Elsevier

    Sergio Ferreira

  158. Functional Properties of Purified Vicilins from Cowpea (Vigna unguiculata) and Pea (Pisum sativum) and Cowpea Protein Isolate

    Article • Journal of Agricultural and Food Chemistry, August 2003, American Chemical Society (ACS)

    Sergio Ferreira

  159. Neuroprotection against Aβ and glutamate toxicity by melatonin: Are GABA receptors involved?

    Article • Neurotoxicity Research, January 2003, Springer Science + Business Media

    Sergio Ferreira, Andrea Paula-Lima

  160. Equilibrium unfolding and conformational plasticity of troponin I and T

    Article • FEBS Journal, October 2002, Wiley

    Sergio Ferreira

  161. Folding of a de Novo Designed Native-like Four-helix Bundle Protein

    Article • Journal of Biological Chemistry, May 2002, Elsevier

    Sergio Ferreira

  162. Article • Cellular and Molecular Neurobiology, January 2002, Springer Science + Business Media

    Sergio Ferreira

  163. Protein dynamics, folding and misfolding: from basic physical chemistry to human conformational diseases

    Article • FEBS Letters, June 2001, Wiley

    Sergio Ferreira

  164. Dimethylsulfoxide promotes K+‐independent activity of pyruvate kinase and the acquisition of the active catalytic conformation

    Article • FEBS Journal, June 2001, Wiley

    Sergio Ferreira

  165. Iron-induced oxidative damage of corn root plasma membrane H+-ATPase

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, June 2001, Elsevier

    Sergio Ferreira

  166. Dual role of glutamatergic neurotransmission on amyloid β1–42 aggregation and neurotoxicity in embryonic avian retina

    Article • Neuroscience Letters, March 2001, Elsevier

    Sergio Ferreira, Andrea Paula-Lima

  167. Crystal structures of bovine beta-lactoglobulin in the orthorhombic space group C2221 . Structural differences between genetic variants A and B and features of the Tanford transition

    Article • FEBS Journal, January 2001, Wiley

    Sergio Ferreira

  168. Folding Intermediates of a Model Three-helix Bundle Protein

    Article • Journal of Biological Chemistry, January 2001, Elsevier

    Sergio Ferreira

  169. Haemozoin in Schistosoma mansoni

    Article • Molecular and Biochemical Parasitology, November 2000, Elsevier

    Sergio Ferreira

  170. Preliminary X-ray diffraction studies of rabbit muscle triose phosphate isomerase (TIM)

    Article • Acta Crystallographica Section D Biological Crystallography, November 2000, International Union of Crystallography

    Sergio Ferreira

  171. Inhibition of the Ecto-ATPdiphosphohydrolase of Schistosoma mansoni by Thapsigargin

    Article • Bioscience Reports, October 2000, Portland Press Ltd.

    Sergio Ferreira

  172. Selective Neoglycosylation Increases the Structural Stability of Vicilin, the 7S Storage Globulin from Pea Seeds

    Article • Archives of Biochemistry and Biophysics, October 2000, Elsevier

    Sergio Ferreira

  173. Pressure denaturation of β‐lactoglobulin

    Article • FEBS Journal, April 2000, Wiley

    Sergio Ferreira

  174. Subunit dissociation and inactivation of pyruvate kinase by hydrostatic pressure

    Article • FEBS Journal, November 1999, Wiley

    Sergio Ferreira

  175. Acidic pH Modulates the Interaction between Human Granulocyte-Macrophage Colony-stimulating Factor and Glycosaminoglycans

    Article • Journal of Biological Chemistry, October 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Marcelo A Carvalho, Sergio Ferreira

  176. Oxidative damage to sarcoplasmic reticulum Ca2+-ATPase at submicromolar iron concentrations: evidence for metal-catalyzed oxidation

    Article • Free Radical Biology and Medicine, September 1998, Elsevier

    Sergio Ferreira

  177. International Symposium on Protein Condensation, in Honor of Gregorio Weber, May 21–25, 1997, Rio de Janeiro, Brazil

    Article • Biophysical Journal, July 1998, Elsevier

    Sergio Ferreira

  178. Divalent cation dependence and inhibition of Schistosoma mansoni ATP diphosphohydrolase by fluorosulfonylbenzoyl adenosine

    Article • FEBS Journal, January 1998, Wiley

    Sergio Ferreira

  179. Kinetics and Energetics of Subunit Dissociation/Unfolding of TIM:  The Importance of Oligomerization for Conformational Persistence and Chemical Stability of Proteins

    Article • Biochemistry, January 1998, American Chemical Society (ACS)

    Sergio Ferreira

  180. Role of Phospholipids in the Protein Stability of an Insect Lipoprotein, Lipophorin from Rhodnius prolixus

    Article • Biochemistry, September 1997, American Chemical Society (ACS)

    Sergio Ferreira

  181. Partial Purification and Immunohistochemical Localization of ATP Diphosphohydrolase from Schistosoma mansoni

    Article • Journal of Biological Chemistry, September 1996, Elsevier

    Sergio Ferreira

  182. Deterministic Pressure Dissociation and Unfolding of Triose Phosphate Isomerase:  Persistent Heterogeneity of a Protein Dimer

    Article • Biochemistry, January 1996, American Chemical Society (ACS)

    Sergio Ferreira

  183. Oxidative damage to sarcoplasmic reticulum Ca2+-pump induced by Fe2+/H2O2/ascorbate is not mediated by lipid peroxidation or thiol oxidation and leads to protein fragmentation

    Article • Molecular and Cellular Biochemistry, January 1996, Springer Science + Business Media

    Sergio Ferreira

  184. Refolding of Triosephosphate Isomerase in Low-Water Media Investigated by Fluorescence Resonance Energy Transfer

    Article • Biochemistry, January 1996, American Chemical Society (ACS)

    Sergio Ferreira

  185. Inter-Active-Site Distance and Solution Dynamics of a Bivalent-Bispecific Single-Chain Antibody Molecule

    Article • Biochemistry, August 1994, American Chemical Society (ACS)

    Sergio Ferreira

  186. Anisotropic Rotational Diffusion of the Adenine Moiety in 1,N6-Ethenoadenosine Triphosphate in Viscous Solvents Investigated by Time-Resolved Fluorescence Spectroscopy

    Article • Journal of the American Chemical Society, June 1994, American Chemical Society (ACS)

    Sergio Ferreira

  187. Betaine counteracts urea‐induced conformational changes and uncoupling of the human erythrocyte Ca2+ pump

    Article • FEBS Journal, May 1994, Wiley

    Sergio Ferreira

  188. Deterministic Pressure-Induced Dissociation of Vicilin, the 7S Storage Globulin from Pea Seeds: Effects of pH and Cosolvents on Oligomer Stability

    Article • Biochemistry, April 1994, American Chemical Society (ACS)

    Sergio Ferreira

  189. FLUORESCENCE LIFETIME AND QUENCHING STUDIES OF SARCOPLASMIC RETICULUM CA2+ ‐ADENOSINE‐5′‐TRIPHOSPHATASE*

    Article • Photochemistry and Photobiology, August 1993, Wiley

    Sergio Ferreira

  190. Characterization and localization of an ATP-diphosphohydrolase on the external surface of the tegument of Schistosoma mansoni

    Article • Molecular and Biochemical Parasitology, April 1993, Elsevier

    Sergio Ferreira

  191. Time-resolved fluorescence of erythrocyte plasma membrane ca2+-atpase in different functional states

    Article • Biophysical Chemistry, April 1992, Elsevier

    Sergio Ferreira

  192. Global analysis of wavelength-resolved fluorescence decay in sarcoplasmic reticulum calcium - ATPase

    Article • Journal of Luminescence, January 1991, Elsevier

    Sergio Ferreira

  193. Hydration and protein substates: Fluorescence of proteins in reverse micelles

    Article • Journal of Molecular Liquids, April 1990, Elsevier

    Sergio Ferreira

  194. Fluorescence studies of the conformational dynamics of parvalbumin in solution: lifetime and rotational motions of the single tryptophan residue

    Article • Biochemistry, December 1989, American Chemical Society (ACS)

    Sergio Ferreira

  195. Probing the Nucleotide Binding Sites of Sarcoplasmic Reticulum Atpase by Photoaffinity Labeling

    Article • Biophysical Journal, January 1986, Elsevier

    Sergio Ferreira