PhD Rui M Brito
University of Coimbra
Faculty Member, Chemistry
My co-authors include
Dr Sandra Macedo-Ribeiro
Teresa Pinho e Melo
Lead optimization of resilient next-generation transthyretin stabilizers for multiple t...
Evaluation by fluorescence, STD-NMR, docking and semi-empirical calculations of the o-N...
Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy
A novel bis-furan scaffold for transthyretin stabilization and amyloid inhibition
European Journal of Medicinal Chemistry
A New Folding Kinetic Mechanism for Human Transthyretin and the Influence of the Amyloi...
International Journal of Molecular Sciences
Enhancing Scoring Performance of Docking-Based Virtual Screening Through Machine Learning
Effect of ethyleneoxide groups of anionic surfactants on lipase activity
A look into amyloid formation by transthyretin: aggregation pathway and a novel kinetic...
Physical Chemistry Chemical Physics
“Structural characterization of the minimal segment of TDP-43 competent for aggregation”
Archives of Biochemistry and Biophysics
A Serpin Released by an Entomopathogen Impairs Clot Formation in Insect Defense System
The Apoptogenic Toxin AIP56 Is a Metalloprotease A-B Toxin that Cleaves NF-κb P65
VEGF-Functionalized Dextran Has Longer Intracellular Bioactivity than VEGF in Endotheli...
Changes in Channel Trafficking and Protein Stability Caused by LQT2 Mutations in the PA...
Functional and conformational changes in the aspartic protease cardosin A induced by TFE
International Journal of Biological Macromolecules
The V30M Amyloidogenic Mutation Decreases the Rate of Refolding Kinetics of the Tetrame...
Spectroscopy An International Journal
Modeling of the Toll-like receptor 3 and a putative Toll-like receptor 3 antagonist enc...
Assessing the Effect of 2D Fingerprint Filtering on ILP-Based Structure-Activity Relati...
FH8 - a small EF-hand protein from Fasciola hepatica
Biological activity of heterologous murine interleukin-10 and preliminary studies on th...
International Journal of Pharmaceutics
Toward the Discovery of Functional Transthyretin Amyloid Inhibitors: Application of Vir...
Journal of Chemical Information and Computer Sciences
P-found: Grid-enabling distributed repositories of protein folding and unfolding simula...
Future Generation Computer Systems
Potentially amyloidogenic conformational intermediates populate the unfolding landscape...
Spatial Clustering of Molecular Dynamics Trajectories in Protein Unfolding Simulations
Comparative Study of Classification Algorithms Using Molecular Descriptors in Toxicolog...
Flash vacuum pyrolysis of 2,2-dioxo-1H,3H-pyrrolo[1,2-c]thiazoles and 2-vinyl-1H-pyrroles
Grid Computing Solutions for Distributed Repositories of Protein Folding and Unfolding ...
P-found: The Protein Folding and Unfolding Simulation Repository
Mining Approximate Motifs in Time Series
Towards Data Warehousing and Mining of Protein Unfolding Simulation Data
Journal of Clinical Monitoring and Computing
Detection of Hydrophobic Clusters in Molecular Dynamics Protein Unfolding Simulations U...
Protein Folding and Unfolding Simulations: A New Challenge for Data Mining
OMICS A Journal of Integrative Biology
Amyloid Formation by Transthyretin: From Protein Stability to Protein Aggregation
Current Medicinal Chemistry - Immunology Endocrine & Metabolic Agents
Comparative calorimetric study of non-amyloidogenic and amyloidogenic variants of the h...
The Tetrameric Protein Transthyretin Dissociates to a Non-native Monomer in Solution: A...
Journal of Biological Chemistry
Solution Structures of the C-Terminal Domain of Cardiac Troponin C Free and Bound to th...
Solution Structures of the C-Terminal Domain of Cardiac Troponin C Free and Bound to t...
The amyloidogenic potential of transthyretin variants correlates with their tendency to...
Assignment and calcium dependence of methionyl .epsilon.C and .epsilon.H resonances in ...
Conformational changes in the metal-binding sites of cardiac troponin C induced by calc...
Comparative NMR studies on cardiac troponin C and a mutant incapable of binding calcium...
Conformation of NADP+ bound to a type II dihydrofolate reductase
Characterization and stereochemistry of cofactor oxidation by a type II dihydrofolate r...
Determination of the critical micelle concentration of surfactants using the fluorescen...
On Mining Protein Unfolding Simulation Data with Inductive Logic Programming
Using Data Mining Techniques to Probe the Role of Hydrophobic Residues in Protein Foldi...
A Knowledge Discovery Method for the Characterization of Protein Unfolding Processes