All Stories

  1. trans-A2B-Corroles containing an oxime moiety: Novel photosensitizers for photodynamic therapy of lung cancer

    Article • European Journal of Medicinal Chemistry, November 2025, Elsevier

    Teresa Pinho e Melo

  2. Synthetic Pathway to trans -A 2 B 2 -Porphyrins: From Oxime-Substituted Dipyrromethanes to Functionaliz...

    Article • The Journal of Organic Chemistry, October 2025, American Chemical Society (ACS)

    Teresa Pinho e Melo

  3. Sulfur dioxide extrusion: Exploring the mechanism behind the formation of highly reactive 5-(trifluoromethyl)azafulvenium methide intermediates

    Article • Journal of Analytical and Applied Pyrolysis, August 2025, Elsevier

    Maria Isabel Soares, Teresa Pinho e Melo

  4. Synthesis of Chiral Spirocyclopropanepenicillanates via [2 + 1] Annulation of 6-Alkylidenepenicillanates and Sulfur Ylides

    Article • The Journal of Organic Chemistry, July 2025, American Chemical Society (ACS)

    Teresa Pinho e Melo

  5. Novel tetradentate N2O2 water-soluble Schiff Base and its Al(III) complex: Synthesis, structural characterization, and correlations between structure and stability against hydrolysis

    Article • Journal of Molecular Structure, June 2025, Elsevier

    Maria Isabel Soares, Teresa Pinho e Melo

  6. P53 and the Ultraviolet Radiation-Induced Skin Response: Finding the Light in the Darkness of Triggered Carcinogenesis

    Article • Cancers, November 2024, MDPI AG

    Teresa Pinho e Melo

  7. Front Cover: Continuous Flow Spirocyclization Reactions: Towards Efficient Synthesis of Chiral Spiropenicillanates (Eur. J. Org. Chem. 42/2024)

    Article • European Journal of Organic Chemistry, November 2024, Wiley

    Teresa Pinho e Melo

  8. Continuous Flow Spirocyclization Reactions: Towards Efficient Synthesis of Chiral Spiropenicillanates

    Article • European Journal of Organic Chemistry, October 2024, Wiley

    Teresa Pinho e Melo

  9. Hydrazone-Functionalized trans-A2B-Corroles: Effective Synergy in Photodynamic Therapy of Lung Cancer

    Article • Journal of Medicinal Chemistry, October 2024, American Chemical Society (ACS)

    Teresa Pinho e Melo

  10. 3-Tetrazolyl-β-carboline derivatives as potential neuroprotective agents

    Article • Bioorganic & Medicinal Chemistry, September 2024, Elsevier

    Teresa Pinho e Melo

  11. Effectiveness of photodynamic therapy on treatment response and survival in patients with recurrent oral squamous cell carcinoma: A systematic review

    Article • Photodiagnosis and Photodynamic Therapy, August 2024, Elsevier

    Teresa Pinho e Melo

  12. Selective Synthesis of 3-(1H-Tetrazol-5-yl)-indoles from 2H-Azirines and Arynes

    Article • ACS Omega, June 2024, American Chemical Society (ACS)

    Teresa Pinho e Melo

  13. Unveiling the Red and Brownish-Green Polymorphs of a Novel ROY Derivative: 2-(4-((3-Cyanothiophen-2-yl)amino)-3-nitrophenyl)Acetic Acid

    Article • Crystal Growth & Design, January 2024, American Chemical Society (ACS)

    Teresa Pinho e Melo

  14. Chiral hydroxymethyl-1H,3H-pyrrolo[1,2-c]thiazoles: the search for selective p53-activating agents for colorectal cancer therapy

    Article • RSC Medicinal Chemistry, January 2024, Royal Society of Chemistry

    Maria Isabel Soares, Teresa Pinho e Melo

  15. On the mechanochemical synthesis of C-scorpionates with an oxime moiety and their application in the copper-catalyzed azide–alkyne cycloaddition (CuAAC) reaction

    Article • New Journal of Chemistry, January 2024, Royal Society of Chemistry

    Teresa Pinho e Melo

  16. Cholesteryl Hemiazelate Present in Cardiovascular Disease Patients Causes Lysosome Dysfunction in Murine Fibroblasts

    Article • Cells, December 2023, MDPI AG

    Maria Isabel Soares, Teresa Pinho e Melo

  17. Novel Foscan®-derived ring-fused chlorins for photodynamic therapy of cancer

    Article • Bioorganic & Medicinal Chemistry, October 2023, Elsevier

    Teresa Pinho e Melo

  18. Organocatalysts for the Asymmetric Neber reaction: Synthesis of Chiral 2‐(Tetrazol‐5‐yl)‐2 H ‐Azirines

    Article • ChemistrySelect, September 2023, Wiley

    Teresa Pinho e Melo, Dr Maria Elisa Silva Serra

  19. Cholesteryl hemiazelate identified in CVD patients causes in vitro and in vivo inflammation

    Article • Journal of Lipid Research, September 2023, Elsevier

    Maria Isabel Soares, Teresa Pinho e Melo

  20. Oxidized cholesteryl ester induces exocytosis of dysfunctional lysosomes in lipidotic macrophages

    Article • Traffic, May 2023, Wiley

    Maria Isabel Soares, Teresa Pinho e Melo

  21. Cholesteryl hemiazelate Identified in Cardiovascular Disease Patients Causesin vitroandin vivoInflammation

    Article • February 2023, Cold Spring Harbor Laboratory Press

    Teresa Pinho e Melo

  22. The role of solvents and concentrations in the properties of oxime bearing A2B corroles

    Article • Physical Chemistry Chemical Physics, January 2023, Royal Society of Chemistry

    Teresa Pinho e Melo

  23. Ring-fused 3β-acetoxyandrost-5-enes as novel neuroprotective agents with cholinesterase inhibitory properties

    Article • The Journal of Steroid Biochemistry and Molecular Biology, January 2023, Elsevier

    Teresa Pinho e Melo

  24. 3-(1,2,3-Triazol-4-yl)-β-Carbolines and 3-(1H-Tetrazol-5-yl)-β-Carbolines: Synthesis and Evaluation as Anticancer Agents

    Article • Pharmaceuticals, December 2022, MDPI AG

    Teresa Pinho e Melo

  25. High Instantaneous Inhibitory Potential of Bictegravir and the New Spiro-β-Lactam BSS-730A for HIV-2 Isolates from RAL-Naïve and RAL-Failing Patients

    Article • International Journal of Molecular Sciences, November 2022, MDPI AG

    Teresa Pinho e Melo

  26. Differential Tunneling‐Driven and Vibrationally‐Induced Reactivity in Isomeric Benzazirines

    Article • Chemistry - A European Journal, October 2022, Wiley

    Teresa Pinho e Melo

  27. Unveiling a family of spiro-β-lactams with anti-HIV and antiplasmodial activity via phosphine-catalyzed [3+2] annulation of 6-alkylidene-penicillanates and allenoates

    Article • Frontiers in Chemistry, October 2022, Frontiers

    Teresa Pinho e Melo

  28. Color Polymorphs of ROY-ol

    Article • Crystal Growth & Design, August 2022, American Chemical Society (ACS)

    Teresa Pinho e Melo

  29. Molecular and crystal structures of N-picryl-m-phenolidine and investigation of single crystal polarized Raman spectra

    Article • Journal of Molecular Structure, August 2022, Elsevier

    Teresa Pinho e Melo

  30. Heterocycles

    Article • June 2022, Wiley

    Teresa Pinho e Melo

  31. Insights into the anticancer activity of chiral alkylidene-β-lactams and alkylidene-γ-lactams: Synthesis and biological investigation

    Article • Bioorganic & Medicinal Chemistry, June 2022, Elsevier

    Teresa Pinho e Melo

  32. Applications of Photodynamic Therapy in Endometrial Diseases

    Article • Bioengineering, May 2022, MDPI AG

    Teresa Pinho e Melo

  33. Ring-Fused meso-Tetraarylchlorins as Auspicious PDT Sensitizers: Synthesis, Structural Characterization, Photophysics, and Biological Evaluation

    Article • Frontiers in Chemistry, April 2022, Frontiers

    Teresa Pinho e Melo

  34. Diels–Alder Cycloaddition Reactions in Sustainable Media

    Article • Molecules, February 2022, MDPI AG

    Teresa Pinho e Melo, Maria Isabel Soares

  35. Ethyl 7-Acetyl-8a-methyl-3-(1-phenyl-1H-tetrazol-5-yl)-1,4,4a,5,6,8a-hexahydro-7H-pyrano[2,3-c]pyridazine-1-carboxylate

    Article • Molbank, February 2022, MDPI AG

    Teresa Pinho e Melo

  36. Isolation and Identification of Cytotoxic Compounds Present in Biomaterial Life®

    Article • Materials, January 2022, MDPI AG

    Teresa Pinho e Melo, Professor Manuel Marques Ferreira

  37. Portrayal of the color polymorphism in the 5-acetyl-derivative of ROY

    Article • CrystEngComm, January 2022, Royal Society of Chemistry

    Teresa Pinho e Melo

  38. Synthesis of novel chiral spiro-β-lactams from nitrile oxides and 6-(Z)-(benzoylmethylene)penicillanate: batch, microwave-induced and continuous flow methodologies

    Article • RSC Advances, January 2022, Royal Society of Chemistry

    Teresa Pinho e Melo

  39. Global Women’s Breakfast (GWB): #UnidaspelaQuímica

    Article • December 2021, Sociedade Portuguesa de Quimica

    Teresa Pinho e Melo

  40. 2,4,6-Trinitro-N-(m-tolyl)aniline: A New Polymorphic Material Exhibiting Different Colors

    Article • Crystal Growth & Design, November 2021, American Chemical Society (ACS)

    Teresa Pinho e Melo

  41. Effectiveness of photodynamic therapy on treatment response and survival of patients with recurrent oral squamous cell carcinoma: a systematic review protocol

    Article • JBI Evidence Synthesis, November 2021, Wolters Kluwer Health

    Teresa Pinho e Melo

  42. Cholesteryl hemiazelate causes lysosome dysfunction impacting vascular smooth muscle cell homeostasis

    Article • Journal of Cell Science, October 2021, The Company of Biologists

    Teresa Pinho e Melo, Maria Isabel Soares

  43. Reduction of Oximes and Hydrazones: Asymmetric and Diastereoselective Approaches

    Article • Current Organic Chemistry, October 2021, Bentham Science Publishers

    Teresa Pinho e Melo

  44. Recent Advances on Functional Group Interconversion

    Article • Current Organic Chemistry, October 2021, Bentham Science Publishers

    Teresa Pinho e Melo

  45. One-Pot Synthetic Approach to Dipyrromethanes and Bis(indolyl)methanes via Nitrosoalkene Chemistry

    Article • Journal of Chemical Education, July 2021, American Chemical Society (ACS)

    Teresa Pinho e Melo

  46. Synthesis and structure-activity relationships of new chiral spiro-β-lactams highly active against HIV-1 and Plasmodium

    Article • European Journal of Medicinal Chemistry, July 2021, Elsevier

    Maria Isabel Soares, Teresa Pinho e Melo

  47. Switching on H-Tunneling through Conformational Control

    Article • Journal of the American Chemical Society, May 2021, American Chemical Society (ACS)

    Teresa Pinho e Melo

  48. Compressive single pixel phosphorescence lifetime and intensity simultaneous imaging: a pilot study using oxygen sensitive biomarkers

    Article • April 2021, SPIE

    Professor António Miguel Morgado, Teresa Pinho e Melo

  49. Recent Advances in the Synthesis of Spiro‐β‐Lactams and Spiro‐δ‐Lactams

    Article • Advanced Synthesis & Catalysis, April 2021, Wiley

    Maria Isabel Soares, Teresa Pinho e Melo

  50. A selective p53 activator and anticancer agent to improve colorectal cancer therapy

    Article • Cell Reports, April 2021, Elsevier

    PhD Filipe Monteiro, Maria Isabel Soares, Teresa Pinho e Melo

  51. Global Impact of COVID-19 on Stroke Care and IV Thrombolysis

    Article • Neurology, March 2021, Wolters Kluwer Health

    Director of the stroke unit, DMSci, clinical research associate professor Helle K. Iversen, Teresa Pinho e Melo

  52. Cholesteryl Hemiazelate Induces Lysosome Dysfunction and Exocytosis in Macrophages

    Article • January 2021, Cold Spring Harbor Laboratory Press

    Teresa Pinho e Melo

  53. Spiro-β-lactam BSS-730A Displays Potent Activity against HIV and Plasmodium

    Article • ACS Infectious Diseases, January 2021, American Chemical Society (ACS)

    Teresa Pinho e Melo

  54. Synthesis of 5H-chromeno[3,4-b]pyridines via DABCO-catalyzed [3 + 3] annulation of 3-nitro-2H-chromenes and allenoates

    Article • Organic & Biomolecular Chemistry, January 2021, Royal Society of Chemistry

    Dr Joaquim Marçalo, Teresa Pinho e Melo, Maria Isabel Soares

  55. Novel fluorinated ring-fused chlorins as promising PDT agents against melanoma and esophagus cancer

    Article • RSC Medicinal Chemistry, January 2021, Royal Society of Chemistry

    Teresa Pinho e Melo

  56. Inducing molecular reactions by selective vibrational excitation of a remote antenna with near-infrared light

    Article • Chemical Communications, January 2021, Royal Society of Chemistry

    Teresa Pinho e Melo

  57. Reactivity of steroidal 1-azadienes toward enamines: an approach to novel chiral penta- and hexacyclic steroids

    Article • Organic & Biomolecular Chemistry, January 2021, Royal Society of Chemistry

    Teresa Pinho e Melo

  58. Strategies and methodologies for the construction of spiro-γ-lactams: an update

    Article • Organic Chemistry Frontiers, January 2021, Royal Society of Chemistry

    Teresa Pinho e Melo, Maria Isabel Soares

  59. Synthesis of Novel Chiral Spiroisoxazolidine‐β‐Lactams from 6‐Alkylidenepenicillanates: A 1,3‐Dipolar Cycloaddition Approach

    Article • European Journal of Organic Chemistry, September 2020, Wiley

    Teresa Pinho e Melo

  60. Platinum(II) ring-fused chlorins as efficient theranostic agents: Dyes for tumor-imaging and photodynamic therapy of cancer

    Article • European Journal of Medicinal Chemistry, August 2020, Elsevier

    Teresa Pinho e Melo

  61. Corroles and Hexaphyrins: Synthesis and Application in Cancer Photodynamic Therapy

    Article • Molecules, July 2020, MDPI AG

    Teresa Pinho e Melo

  62. A Novel Bioanalytical Method for the Determination of Opioids in Blood and Pericardial Fluid

    Article • Journal of Analytical Toxicology, June 2020, Oxford University Press (OUP)

    Teresa Pinho e Melo

  63. Proceedings of the CIMAGO Meeting – Challenges in Oncobiology Coimbra, 31st january 2020

    Article • Medicine, June 2020, Wolters Kluwer Health

    Teresa Pinho e Melo

  64. Spiro-Lactams as Novel Antimicrobial Agents

    Article • Current Topics in Medicinal Chemistry, February 2020, Bentham Science Publishers

    Teresa Pinho e Melo, Maria Isabel Soares

  65. Meso-Substituted Corroles from Nitrosoalkenes and Dipyrromethanes

    Article • The Journal of Organic Chemistry, January 2020, American Chemical Society (ACS)

    Teresa Pinho e Melo

  66. “The Chemistry of Allenes”

    Article • Current Organic Chemistry, January 2020, Bentham Science Publishers

    Teresa Pinho e Melo

  67. Asymmetric Neber Reaction in the Synthesis of Chiral 2-(Tetrazol-5-yl)-2H-Azirines

    Article • Synlett, December 2019, Thieme Publishing Group

    Teresa Pinho e Melo

  68. Current Advances in the Synthesis of Valuable Dipyrromethane Scaffolds: Classic and New Methods

    Article • Molecules, November 2019, MDPI AG

    Teresa Pinho e Melo

  69. Cover Feature: Flow Chemistry: Towards A More Sustainable Heterocyclic Synthesis (Eur. J. Org. Chem. 43/2019)

    Article • European Journal of Organic Chemistry, November 2019, Wiley

    Teresa Pinho e Melo

  70. Flow Chemistry: Towards A More Sustainable Heterocyclic Synthesis

    Article • European Journal of Organic Chemistry, October 2019, Wiley

    Teresa Pinho e Melo

  71. Ring-Fused Diphenylchlorins as Potent Photosensitizers for Photodynamic Therapy Applications: In Vitro Tumor Cell Biology and in Vivo Chick Embryo Chorioallantoic Membrane Studies

    Article • ACS Omega, October 2019, American Chemical Society (ACS)

    Mafalda Laranjo, Teresa Pinho e Melo

  72. New 3-tetrazolyl-β-carbolines and β-carboline-3-carboxylates with anti-cancer activity

    Article • European Journal of Medicinal Chemistry, October 2019, Elsevier

    Teresa Pinho e Melo

  73. Tetrahydropyrazolo[1,5-a]pyridine-fused steroids and their in vitro biological evaluation in prostate cancer

    Article • European Journal of Medicinal Chemistry, September 2019, Elsevier

    Teresa Pinho e Melo

  74. Natural deep eutectic solvents in the hetero-Diels–Alder approach to bis(indolyl)methanes

    Article • Monatshefte für Chemie - Chemical Monthly, June 2019, Springer Science + Business Media

    Teresa Pinho e Melo

  75. Biogeographic differences in the allelopathy of leaf surface extracts of an invasive weed

    Article • Biological Invasions, June 2019, Springer Science + Business Media

    Teresa Pinho e Melo

  76. Phosphane-Catalyzed [3+2] Annulation of Allenoates with 3-Nitro-2H -chromenes: Synthesis of Tetrahydrocyclopenta[c ]chromenes

    Article • European Journal of Organic Chemistry, June 2019, Wiley

    Maria Isabel Soares, Teresa Pinho e Melo

  77. Lead optimization of resilient next-generation transthyretin stabilizers for multiple target-product profiles: approaching the CNS

    Article • Amyloid, March 2019, Taylor & Francis

    Teresa Pinho e Melo, PhD Rui M Brito, Zaida Almeida

  78. A Review on (Hydro)Porphyrin-Loaded Polymer Micelles: Interesting and Valuable Platforms for Enhanced Cancer Nanotheranostics

    Article • Pharmaceutics, February 2019, MDPI AG

    Teresa Pinho e Melo

  79. ONE-POT DIASTEREOSELECTIVE SYNTHESIS OF CHIRAL TRICYCLIC l-CYSTEINE AND d-PENICILLAMINE DERIVATIVES: A LABORATORY EXPERIMENT

    Article • Química Nova, January 2019, Sociedade Brasileira de Quimica (SBQ)

    Maria Isabel Soares, Teresa Pinho e Melo

  80. Recent Advances in the Chemistry of Conjugated Nitrosoalkenes and Azoalkenes

    Article • Chemical Reviews, November 2018, American Chemical Society (ACS)

    Teresa Pinho e Melo

  81. Regioselectivity in Hetero Diels–Alder Reactions

    Article • Journal of Chemical Education, November 2018, American Chemical Society (ACS)

    Teresa Pinho e Melo

  82. Reactivity of Steroidal 1-Azadienes toward Carbonyl Compounds under Enamine Catalysis: Chiral Penta- and Hexacyclic Steroids

    Article • Organic Letters, July 2018, American Chemical Society (ACS)

    Teresa Pinho e Melo

  83. Advances on photodynamic therapy of melanoma through novel ring-fused 5,15-diphenylchlorins

    Article • European Journal of Medicinal Chemistry, February 2018, Elsevier

    Ana Cristina Gonçalves, Mafalda Laranjo, Teresa Pinho e Melo

  84. Hetero-Diels-Alder reactions of novel 3-triazolyl-nitrosoalkenes as an approach to functionalized 1,2,3-triazoles with antibacterial profile

    Article • European Journal of Medicinal Chemistry, January 2018, Elsevier

    Teresa Pinho e Melo, Dora Cristina Silva Costa

  85. Properties and patterns in anion-receptors: A closer look at bambusurils

    Article • Journal of Molecular Liquids, September 2017, Elsevier

    Dr Tânia F. G. G. Cova, Teresa Pinho e Melo

  86. Advances on photodynamic therapy through new pyridine-fused diphenylchlorins as photosensitizers for melanoma treatment

    Article • Porto Biomedical Journal, September 2017, Wolters Kluwer Health

    Teresa Pinho e Melo

  87. Hetero-Diels-Alder and Ring-Opening Reactions of Furans Applied to the Synthesis of Functionalized Heterocycles

    Article • European Journal of Organic Chemistry, July 2017, Wiley

    Teresa Pinho e Melo

  88. Synthesis and anti-cancer activity of chiral tetrahydropyrazolo[1,5- a ]pyridine-fused steroids

    Article • Steroids, June 2017, Elsevier

    Teresa Pinho e Melo

  89. Biological Evaluation of Dipyrromethanes in Cancer Cell Lines: Antiproliferative and Pro-apoptotic Properties

    Article • ChemMedChem, April 2017, Wiley

    Teresa Pinho e Melo

  90. Bambusurils as effective ion caging agents: Does desolvation guide conformation?

    Article • Chemical Physics Letters, March 2017, Elsevier

    Dr Tânia F. G. G. Cova, Teresa Pinho e Melo

  91. Oxygen sensing with Pt(II)chlorins

    Article • ACS Medicinal Chemistry Letters, February 2017, American Chemical Society (ACS)

    Professor Mathias O. Senge, Mafalda Laranjo, Teresa Pinho e Melo

  92. Cholesteryl hemiesters alter lysosome structure and function and induce proinflammatory cytokine production in macrophages

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, February 2017, Elsevier

    Maria Isabel Soares, Teresa Pinho e Melo

  93. Hetero-Diels-Alder approach to Bis(indolyl)methanes

    Article • Bioorganic & Medicinal Chemistry, February 2017, Elsevier

    Teresa Pinho e Melo

  94. Conformational behaviour, photochemistry and flash vacuum pyrolysis of a 2-(1H-tetrazol-1-yl)thiophene

    Article • New Journal of Chemistry, January 2017, Royal Society of Chemistry

    Maria Isabel Soares, Teresa Pinho e Melo

  95. A novel bis-furan scaffold for transthyretin stabilization and amyloid inhibition

    Article • European Journal of Medicinal Chemistry, October 2016, Elsevier

    PhD Rui M Brito, Zaida Almeida, Teresa Pinho e Melo, Dora Cristina Silva Costa

  96. (1H-Tetrazol-5-yl)-Allenes: Building Blocks for Tetrazolyl Heterocycles

    Article • The Journal of Organic Chemistry, September 2016, American Chemical Society (ACS)

    Teresa Pinho e Melo

  97. Synthesis of Thieno[2,3-d]pyrimidines via Microwave-Assisted Thermolysis of 1-(Thiophene-2-yl)-1H-tetrazoles

    Article • ChemistrySelect, September 2016, Wiley

    Maria Isabel Soares, Teresa Pinho e Melo

  98. d-Penicillamine and l-cysteine derived thiazolidine catalysts: an efficient approach to both enantiomers of secondary alcohols

    Article • Tetrahedron, September 2016, Elsevier

    Dr Maria Elisa Silva Serra, Teresa Pinho e Melo, Dora Cristina Silva Costa

  99. Reactivity of 1-arylnitrosoethylenes towards indole derivatives

    Article • Monatshefte für Chemie - Chemical Monthly, June 2016, Springer Science + Business Media

    Teresa Pinho e Melo

  100. Chemistry of aza- and diazafulvenium methides in heterocyclic synthesis

    Article • Pure and Applied Chemistry, May 2016, De Gruyter

    Teresa Pinho e Melo

  101. 11th National Meeting of Organic Chemistry and 4th Meeting of Therapeutic Chemistry

    Article • Pharmaceuticals, March 2016, MDPI AG

    Rui Moreira, Teresa Pinho e Melo

  102. Synthesis of New 2-Halo-2-(1H-tetrazol-5-yl)-2H-azirines via a Non-Classical Wittig Reaction

    Article • Molecules, December 2015, MDPI AG

    Teresa Pinho e Melo

  103. Novel 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine fused chlorins as very active photodynamic agents for melanoma cells

    Article • European Journal of Medicinal Chemistry, October 2015, Elsevier

    Ana Cristina Gonçalves, Mafalda Laranjo, Teresa Pinho e Melo

  104. Inter-regional variation on leaf surface defenses in native and non-native Centaurea solstitialis plants

    Article • Biochemical Systematics and Ecology, October 2015, Elsevier

    Teresa Pinho e Melo

  105. Exploring the Chemistry of Furans: Synthesis of Functionalized Bis(furan-2-yl)methanes and 1,6-Dihydropyridazines

    Article • European Journal of Organic Chemistry, September 2015, Wiley

    Teresa Pinho e Melo

  106. Synthesis and Reactivity of Aziridines with Internal Dipolarophiles: An Approach to 1,4-Dihydrochromeno[4,3-b]pyrroles and 3-Methylenechromano[4,3-b]pyrroles

    Article • Synthesis, June 2015, Thieme Publishing Group

    Teresa Pinho e Melo

  107. Synthesis and thermal reactivity of thiazolo[3,4-a]benzimidazole-2,2-dioxides: approach to 1H-benzo[d]imidazoles via novel benzo-2,5-diazafulvenium methides

    Article • Tetrahedron, June 2015, Elsevier

    Maria Isabel Soares, Teresa Pinho e Melo

  108. Thermolysis of 1-(thiophen-2-yl)-1H-tetrazoles: a route to thiophene-fused imidazoles and pyrimidines

    Article • Tetrahedron, May 2015, Elsevier

    Maria Isabel Soares, Teresa Pinho e Melo

  109. Novel approach to bis(indolyl)methanes: De novo synthesis of 1-hydroxyiminomethyl derivatives with anti-cancer properties

    Article • European Journal of Medicinal Chemistry, March 2015, Elsevier

    Teresa Pinho e Melo

  110. Pericyclic Reactions of Azafulvenium Methides Bearing Internal Dipolarophiles - Synthesis of Chromene and Chromane Derivatives

    Article • European Journal of Organic Chemistry, January 2015, Wiley

    Maria Isabel Soares, Teresa Pinho e Melo

  111. Synthesis of chiral hexacyclic steroids via [8π + 2π] cycloaddition of diazafulvenium methides

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    Teresa Pinho e Melo

  112. Reactions of Nitrosoalkenes with Dipyrromethanes and Pyrroles: Insight into the Mechanistic Pathway

    Article • The Journal of Organic Chemistry, October 2014, American Chemical Society (ACS)

    Teresa Pinho e Melo

  113. Conjugate Addition of Pyrazoles to Halogenated Nitroso- and Azoalkenes: A New Entry to Novel Bis(pyrazol-1-yl)methanes

    Article • Synlett, October 2014, Thieme Publishing Group

    Teresa Pinho e Melo

  114. Reactivity of Dipyrromethanes towards Azoalkenes: Synthesis of Functionalized Dipyrromethanes, Calix[4]pyrroles, and Bilanes

    Article • European Journal of Organic Chemistry, September 2014, Wiley

    Teresa Pinho e Melo

  115. Selective Synthesis of Tetrasubstituted 4-(Tetrazol-5-yl)-1H-imidazoles from 2-(Tetrazol-5-yl)-2H-azirines (Eur. J. Org. Chem. 24/2014)

    Article • European Journal of Organic Chemistry, August 2014, Wiley

    Teresa Pinho e Melo

  116. Selective Synthesis of Tetrasubstituted 4-(Tetrazol-5-yl)-1H-imidazoles from 2-(Tetrazol-5-yl)-2H-azirines

    Article • European Journal of Organic Chemistry, June 2014, Wiley

    Teresa Pinho e Melo

  117. Synthesis of chiral spiropyrazoline-β-lactams and spirocyclopropyl-β-lactams from 6-alkylidenepenicillanates

    Article • Tetrahedron, June 2014, Elsevier

    Teresa Pinho e Melo

  118. Recent Developments in the Synthesis of Dipyrromethanes. A Review

    Article • Organic Preparations and Procedures International, May 2014, Taylor & Francis

    Teresa Pinho e Melo

  119. Targeting triple-negative breast cancer cells with 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles

    Article • European Journal of Medicinal Chemistry, May 2014, Elsevier

    Teresa Pinho e Melo, Ana Cristina Gonçalves, Mafalda Laranjo, Maria Isabel Soares

  120. 1‐Methyl‐5‐(trifluoromethyl)azafulvenium Methide, an Intermediate That Undergoes Reaction through “Unusual” cis‐exo‐1,3‐ and trans‐exo‐1,7‐Cycloadditions

    Article • European Journal of Organic Chemistry, April 2014, Wiley

    Teresa Pinho e Melo

  121. Microwave-induced Pericyclic Reactions of Aza- and Diazafulvenium Methides

    Article • Current Microwave Chemistry, March 2014, Bentham Science Publishers

    Teresa Pinho e Melo, Maria Isabel Soares

  122. On-Water Synthesis of Dipyrromethanes via Bis-Hetero-Diels–Alder Reaction of Azo- and Nitrosoalkenes with Pyrrole

    Article • Synlett, December 2013, Thieme Publishing Group

    Teresa Pinho e Melo

  123. ChemInform Abstract: Neber Approach to 2-(Tetrazol-5-yl)-2H-azirines.

    Article • ChemInform, November 2013, Wiley

    Teresa Pinho e Melo

  124. Reactivity of sarcosine and 1,3-thiazolidine-4-carboxylic acid towards salicylaldehyde-derived alkynes and allenes

    Article • Tetrahedron, November 2013, Elsevier

    Teresa Pinho e Melo

  125. The Neber Approach to 2-(Tetrazol-5-yl)-2H-Azirines

    Article • The Journal of Organic Chemistry, July 2013, American Chemical Society (ACS)

    Teresa Pinho e Melo

  126. ChemInform Abstract: Functionalization of Dipyrromethanes via Hetero-Diels-Alder Reaction with Azo- and Nitrosoalkenes.

    Article • ChemInform, June 2013, Wiley

    Teresa Pinho e Melo

  127. ChemInform Abstract: Thiazolo[3,4-b]indazole-2,2-dioxides as Masked Extended Dipoles: Pericyclic Reactions of Benzodiazafulvenium Methides.

    Article • ChemInform, May 2013, Wiley

    Teresa Pinho e Melo

  128. Synthesis and thermal reactivity of 3-benzyl-7-trifluoromethyl-1H,3H-pyrrolo[1,2-c]thiazole-2,2-dioxide

    Article • Tetrahedron, May 2013, Elsevier

    Teresa Pinho e Melo

  129. Synthesis of Chiral Spirocyclopentenyl‐β‐lactams through Phosphane‐Catalyzed [3+2] Annulation of Allenoates with 6‐Alkylidenepenicillanates

    Article • European Journal of Organic Chemistry, April 2013, Wiley

    Teresa Pinho e Melo

  130. ChemInform Abstract: Aziridines in Formal [3 + 2] Cycloadditions: Synthesis of Five-Membered Heterocycles

    Article • ChemInform, March 2013, Wiley

    Teresa Pinho e Melo

  131. ChemInform Abstract: Immobilized Catalysts for Hydroformylation Reactions: A Versatile Tool for Aldehyde Synthesis

    Article • ChemInform, March 2013, Wiley

    Mario Calvete, Teresa Pinho e Melo

  132. Functionalization of dipyrromethanes via hetero-Diels–Alder reaction with azo- and nitrosoalkenes

    Article • Tetrahedron Letters, March 2013, Elsevier

    Teresa Pinho e Melo

  133. Chiral 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles with anti-breast cancer properties

    Article • European Journal of Medicinal Chemistry, February 2013, Elsevier

    Teresa Pinho e Melo, Mafalda Laranjo, Maria Isabel Soares

  134. Thiazolo[3,4-b]indazole-2,2-dioxides as Masked Extended Dipoles: Pericyclic Reactions of Benzodiazafulvenium Methides

    Article • The Journal of Organic Chemistry, December 2012, American Chemical Society (ACS)

    Teresa Pinho e Melo, Maria Isabel Soares

  135. UV-Laser Photochemistry of Isoxazole Isolated in a Low-Temperature Matrix

    Article • The Journal of Organic Chemistry, September 2012, American Chemical Society (ACS)

    Igor Reva, Teresa Pinho e Melo

  136. Immobilized Catalysts for Hydroformylation Reactions: A Versatile Tool for Aldehyde Synthesis

    Article • European Journal of Organic Chemistry, September 2012, Wiley

    Mario Calvete, Teresa Pinho e Melo

  137. ChemInform Abstract: [4 + 2] Cycloadditions of 3-Tetrazolyl-1,2-diaza-1,3-butadienes: Synthesis of 3-Tetrazolyl-1,4,5,6-tetrahydropyridazines.

    Article • ChemInform, August 2012, Wiley

    Teresa Pinho e Melo

  138. Aziridines in Formal [3+2] Cycloadditions: Synthesis of Five‐Membered Heterocycles

    Article • European Journal of Organic Chemistry, July 2012, Wiley

    Teresa Pinho e Melo

  139. Chiral spiro-β-lactams from 6-diazopenicillanates

    Article • Tetrahedron, May 2012, Elsevier

    Teresa Pinho e Melo

  140. ChemInform Abstract: Nitrogen‐Bridged Heterocycles via Cycloaddition of Non‐classical Heterocyclic‐Fused‐[c]thiazoles.

    Article • ChemInform, March 2012, Wiley

    Teresa Pinho e Melo

  141. [4+2] Cycloadditions of 3‐Tetrazolyl‐1,2‐diaza‐1,3‐butadienes: Synthesis of 3‐Tetrazolyl‐1,4,5,6‐tetrahydropyridazines

    Article • European Journal of Organic Chemistry, February 2012, Wiley

    Teresa Pinho e Melo

  142. ChemInform Abstract: Diels-Alder Reactions of 3-(1H-Tetrazol-5-yl)-nitrosoalkenes: Synthesis of Functionalized 5-(Substituted)-1H-tetrazoles.

    Article • ChemInform, February 2012, Wiley

    Teresa Pinho e Melo

  143. ChemInform Abstract: Synthesis of Pyrroles in Supercritical Carbon Dioxide: Formal [3 + 2] Cycloaddition of 2-Benzoyl-aziridines and Allenoates.

    Article • ChemInform, February 2012, Wiley

    Teresa Pinho e Melo

  144. ChemInform Abstract: Five-Membered Heterocycles: 1,2-Azoles. Part 2. Isoxazoles and Isothiazoles

    Article • ChemInform, December 2011, Wiley

    Teresa Pinho e Melo

  145. Diels–Alder reactions of 3-(1H-tetrazol-5-yl)-nitrosoalkenes: synthesis of functionalized 5-(substituted)-1H-tetrazoles

    Article • Tetrahedron, November 2011, Elsevier

    Teresa Pinho e Melo

  146. The Pyrolysis of Isoxazole Revisited: A New Primary Product and the Pivotal Role of the Vinylnitrene. A Low-Temperature Matrix Isolation and Computational Study

    Article • Journal of the American Chemical Society, October 2011, American Chemical Society (ACS)

    Igor Reva, Teresa Pinho e Melo

  147. ChemInform Abstract: Allenes as Building Blocks in Heterocyclic Chemistry

    Article • ChemInform, October 2011, Wiley

    Teresa Pinho e Melo

  148. Structure and photochemical behaviour of 3-azido-acrylophenones: a matrix isolation infrared spectroscopy study

    Article • Tetrahedron, October 2011, Elsevier

    Andrea Gomez-Zavaglia, Teresa Pinho e Melo

  149. Nitrogen-bridged heterocycles via cycloaddition of non-classical heterocyclic-fused-[c]thiazoles

    Article • Tetrahedron, October 2011, Elsevier

    Teresa Pinho e Melo, Maria Isabel Soares

  150. Synthesis of Pyrroles in Supercritical Carbon Dioxide: Formal [3+2] Cycloaddition of 2-Benzoyl-Aziridines and Allenoates

    Article • Synthesis, September 2011, Thieme Publishing Group

    Teresa Pinho e Melo

  151. Five‐Membered Heterocycles: 1,2‐Azoles. Part 2. Isoxazoles and Isothiazoles

    Article • June 2011, Wiley

    Teresa Pinho e Melo

  152. [8π+2π] Cycloaddition of meso‐Tetra‐ and 5,15‐Diarylporphyrins: Synthesis and Photophysical Characterization of Stable Chlorins and Bacteriochlorins

    Article • European Journal of Organic Chemistry, June 2011, Wiley

    Teresa Pinho e Melo

  153. Allenes as building blocks in heterocyclic chemistry

    Article • Monatshefte für Chemie - Chemical Monthly, May 2011, Springer Science + Business Media

    Teresa Pinho e Melo

  154. ChemInform Abstract: Synthesis of Azides

    Article • ChemInform, April 2011, Wiley

    Teresa Pinho e Melo

  155. ChemInform Abstract: A Hetero-Diels-Alder Approach to Functionalized 1H-Tetrazoles: Synthesis of Tetrazolyl-1,2-oxazines, -oximes and 5-(1-Aminoalkyl)-1H-tetrazoles.

    Article • ChemInform, March 2011, Wiley

    Teresa Pinho e Melo

  156. ChemInform Abstract: Reactivity of Allenoates Towards Aziridines: Synthesis of Functionalized Methylenepyrrolidines and Pyrroles.

    Article • ChemInform, February 2011, Wiley

    Teresa Pinho e Melo

  157. Photochemistry and Vibrational Spectra of Matrix-Isolated Methyl 4-Chloro-5-phenylisoxazole-3-carboxylate

    Article • The Journal of Physical Chemistry A, February 2011, American Chemical Society (ACS)

    Teresa Pinho e Melo

  158. ChemInform Abstract: 4-Isoxazolines and Pyrroles from Allenoates.

    Article • ChemInform, December 2010, Wiley

    Teresa Pinho e Melo

  159. ChemInform Abstract: Synthesis and Biological Evaluation of New Naphthoquinone-Containing Pyrrolo-Thiazoles as Anticancer Agents.

    Article • ChemInform, December 2010, Wiley

    Mafalda Laranjo, Teresa Pinho e Melo

  160. A hetero-Diels–Alder approach to functionalized 1H-tetrazoles: synthesis of tetrazolyl-1,2-oxazines, -oximes and 5-(1-aminoalkyl)-1H-tetrazoles

    Article • Tetrahedron Letters, December 2010, Elsevier

    Teresa Pinho e Melo

  161. Reactivity of allenoates towards aziridines: synthesis of functionalized methylenepyrrolidines and pyrroles

    Article • Tetrahedron, November 2010, Elsevier

    Teresa Pinho e Melo

  162. Novel Approach to Chlorins and Bacteriochlorins: [8π+2π] Cycloaddition of Diazafulvenium Methides with Porphyrins

    Article • European Journal of Organic Chemistry, October 2010, Wiley

    Teresa Pinho e Melo

  163. ChemInform Abstract: Diastereoselective Aza-Baylis-Hillman Reactions: Synthesis of Chiral α-Allenylamines and 2-Azetines from Allenic Esters.

    Article • ChemInform, October 2010, Wiley

    Teresa Pinho e Melo

  164. Chiral 6-hydroxymethyl-1H,3H-pyrrolo[1,2-c]thiazoles: Novel antitumor DNA monoalkylating agents

    Article • European Journal of Medicinal Chemistry, October 2010, Elsevier

    Teresa Pinho e Melo, Mafalda Laranjo, Maria Isabel Soares

  165. Novel antitumor DNA monoalkylating agents: Synthesis and biological evaluation

    Article • BMC Proceedings, September 2010, Springer Science + Business Media

    Maria Isabel Soares, Teresa Pinho e Melo

  166. ChemInform Abstract: 4-Isoxazolines: Scaffolds for Organic Synthesis

    Article • ChemInform, September 2010, Wiley

    Teresa Pinho e Melo

  167. Stereoselective formation of tertiary and quaternary carbon centers via inverse conjugate addition of carbonucleophiles to allenic esters

    Article • Tetrahedron, September 2010, Elsevier

    Teresa Pinho e Melo

  168. ChemInform Abstract: Synthesis of Isoquinolines by Cycloaddition of Arynes to 1,2,4- Triazines.

    Article • ChemInform, September 2010, Wiley

    Teresa Pinho e Melo

  169. ChemInform Abstract: Diels-Alder Reactions of 2-Azadienes Derived from Cysteine Methyl Ester.

    Article • ChemInform, August 2010, Wiley

    Teresa Pinho e Melo

  170. ChemInform Abstract: Aza Cope Rearrangement of Schiff Bases Derived from endo-Norbornen-5- amines.

    Article • ChemInform, August 2010, Wiley

    Teresa Pinho e Melo

  171. ChemInform Abstract: Diels-Alder Reactions of 2-Azadienes Derived from Cysteine and Serine Methyl Esters and Aldehydes.

    Article • ChemInform, August 2010, Wiley

    Teresa Pinho e Melo

  172. ChemInform Abstract: Attempted Intramolecular Diels-Alder Reactions of 2-Azadienes: Alternative Dimerization and Dipolar Cycloaddition Pathways.

    Article • ChemInform, August 2010, Wiley

    Teresa Pinho e Melo

  173. Conformational Space and Vibrational Spectra of Methyl 4-Chloro-5-phenyl-1,3-oxazole-2-carboxylate

    Article • The Journal of Physical Chemistry A, August 2010, American Chemical Society (ACS)

    Teresa Pinho e Melo

  174. ChemInform Abstract: The Use of 2-Azadienes in the Diels-Alder Reaction

    Article • ChemInform, August 2010, Wiley

    Teresa Pinho e Melo

  175. ChemInform Abstract: The Reaction of an α-Oxophosphonium Ylide with Halogens: 2,3- Disubstituted Diethyl Butenedioates from Diethyl 2-Oxo-3- triphenylphosphoroanylidenebutanedioate.

    Article • ChemInform, August 2010, Wiley

    Teresa Pinho e Melo

  176. 4-Isoxazolines and pyrroles from allenoates

    Article • Tetrahedron, August 2010, Elsevier

    Teresa Pinho e Melo

  177. Synthesis and biological evaluation of new naphthoquinone‐containing pyrrolo‐thiazoles as anticancer agents

    Article • Journal of Heterocyclic Chemistry, July 2010, Wiley

    Teresa Pinho e Melo, Mafalda Laranjo, Antonio Rocha Gonsalves

  178. ChemInform Abstract: Diels-Alder Reactions of Acyclic 2-Azadienes: A Semiempirical Molecular Orbital Study.

    Article • ChemInform, June 2010, Wiley

    Teresa Pinho e Melo

  179. ChemInform Abstract: Synthesis of 2-Halo-2H-azirines from Phosphorus Ylides.

    Article • ChemInform, June 2010, Wiley

    Teresa Pinho e Melo

  180. ChemInform Abstract: Intramolecular Dipolar Cycloaddition Reaction of 5H,7H-Thiazolo[3,4-c]oxazol-4-ium-1-olates: Synthesis of Chiral 1H-Pyrrolo[1,2-c]thiazole Derivatives.

    Article • ChemInform, June 2010, Wiley

    Teresa Pinho e Melo

  181. ChemInform Abstract: A New Route to Cross-Conjugated Bis(enamines) and an Unusual Reaction with DDQ.

    Article • ChemInform, June 2010, Wiley

    Teresa Pinho e Melo

  182. ChemInform Abstract: Intermolecular Dipolar Cycloaddition Reactions of 5H,7H-Thiazolo[3,4-c]oxazol-4-ium-1-olates.

    Article • ChemInform, June 2010, Wiley

    Teresa Pinho e Melo

  183. 4‐Isoxazolines: Scaffolds for Organic Synthesis

    Article • European Journal of Organic Chemistry, June 2010, Wiley

    Teresa Pinho e Melo

  184. Diastereoselective Aza‐Baylis–Hillman Reactions: Synthesis of Chiral α‐Allenylamines and 2‐Azetines from Allenic Esters

    Article • European Journal of Organic Chemistry, May 2010, Wiley

    Teresa Pinho e Melo

  185. ChemInform Abstract: Synthesis of 2-Halo-2H-azirines.

    Article • ChemInform, May 2010, Wiley

    Teresa Pinho e Melo

  186. ChemInform Abstract: Reactivity of 2-Halo-2H-azirines. Part 1. Reactions with Nucleophiles.

    Article • ChemInform, May 2010, Wiley

    Teresa Pinho e Melo

  187. ChemInform Abstract: Reactivity of 2-Halo-2H-azirines. Part 2. Thermal Ring Expansion Reactions: Synthesis of 4-Haloisoxazoles.

    Article • ChemInform, May 2010, Wiley

    Teresa Pinho e Melo

  188. ChemInform Abstract: Cycloaddition Reactions of 3-Aryl-5-phenyl-5H,7H-thiazolo[3,4-c]oxazol-4-ium-1-olates.

    Article • ChemInform, May 2010, Wiley

    Teresa Pinho e Melo

  189. ChemInform Abstract: Allenes as Dipolarophiles and 1,3-Dipole Precursors: Synthesis of Carbocyclic and Heterocyclic Compounds

    Article • ChemInform, May 2010, Wiley

    Teresa Pinho e Melo

  190. ChemInform Abstract: Synthesis of Chiral Pyrrolo[1,2-c]thiazoles via Intramolecular Dipolar Cycloaddition of Muenchnones: An Interesting Rearrangement to Pyrrolo[1,2-c]thiazines.

    Article • ChemInform, May 2010, Wiley

    Teresa Pinho e Melo

  191. ChemInform Abstract: Cycloaddition of Trifluoromethyl Azafulvenium Methides: Synthesis of New Trifluoromethylpyrrole-Annulated Derivatives.

    Article • ChemInform, April 2010, Wiley

    Teresa Pinho e Melo

  192. ChemInform Abstract: Reactivity of Allenoates Toward Aziridines: [3 + 2] and Formal [3 + 2] Cycloadditions.

    Article • ChemInform, February 2010, Wiley

    Teresa Pinho e Melo

  193. ChemInform Abstract: Microwave‐Assisted 1,3‐Dipolar Cycloaddition: An Eco‐Friendly Approach to Five‐Membered Heterocycles.

    Article • ChemInform, January 2010, Wiley

    Professor Marta Pineiro, Teresa Pinho e Melo

  194. Cycloaddition of trifluoromethyl azafulvenium methides: synthesis of new trifluoromethylpyrrole-annulated derivatives

    Article • Tetrahedron Letters, January 2010, Elsevier

    Teresa Pinho e Melo

  195. Synthesis of Azides

    Article • November 2009, Wiley

    Teresa Pinho e Melo

  196. Reactivity of allenoates toward aziridines: [3+2] and formal [3+2] cycloadditions

    Article • Tetrahedron Letters, November 2009, Elsevier

    Teresa Pinho e Melo

  197. Microwave-Assisted 1,3-Dipolar Cycloaddition: an Eco-Friendly Approach to Five-Membered Heterocycles

    Article • European Journal of Organic Chemistry, November 2009, Wiley

    Teresa Pinho e Melo, Professor Marta Pineiro

  198. New chiral building blocks of β-peptoid analogs

    Article • Tetrahedron, November 2009, Elsevier

    Teresa Pinho e Melo

  199. Allenes as Dipolarophiles and 1,3-Dipole Precursors: Synthesis of Carbocyclic and Heterocyclic Compounds

    Article • Current Organic Chemistry, September 2009, Bentham Science Publishers

    Teresa Pinho e Melo

  200. Microwave-assisted reactions of allenic esters: [3+2] annulations and allenoate-Claisen rearrangement

    Article • ARKIVOC, July 2009, ARKAT USA, Inc.

    Teresa Pinho e Melo

  201. Synthesis of Functionalized N-Vinyl Nitrogen-Containing Heterocycles

    Article • Synthesis, May 2009, Thieme Publishing Group

    Teresa Pinho e Melo

  202. On the photophysical behaviour of 4-halo-5-phenyl-oxazoles and isoxazoles: A correction and observations on the photoinduced isomerisation and degradation of methyl 4-halo-5-phenyl-isoxazole-3-carboxylates

    Article • Chemical Physics Letters, May 2009, Elsevier

    Teresa Pinho e Melo

  203. ChemInform Abstract: Flash Vacuum Pyrolysis of 2,2-Dioxo-1H,3H-pyrrolo[1,2-c]thiazoles and 2-Vinyl-1H-pyrroles.

    Article • ChemInform, March 2009, Wiley

    Teresa Pinho e Melo

  204. Spectroscopic and theoretical investigation of the conformational space of a pyrazolo-thiazole precursor of extended dipole diazafulvenium methide intermediates

    Article • Journal of Molecular Structure, March 2009, Elsevier

    Teresa Pinho e Melo

  205. 4-Halo-1,3-oxazoles: Unambiguous structural assignment of 2-halo-2-benzoyl-2H-azirine-3-carboxylates thermal ring expansion products

    Article • Journal of Molecular Structure, February 2009, Elsevier

    Teresa Pinho e Melo

  206. ChemInform Abstract: Microwave-Assisted Generation and Reactivity of Aza- and Diazafulvenium Methides: Heterocycles via Pericyclic Reactions.

    Article • ChemInform, November 2008, Wiley

    Teresa Pinho e Melo

  207. Flash vacuum pyrolysis of 2,2-dioxo-1H,3H-pyrrolo[1,2-c]thiazoles and 2-vinyl-1H-pyrroles

    Article • Tetrahedron, October 2008, Elsevier

    Teresa Pinho e Melo, PhD Rui M Brito, Maria Isabel Soares

  208. Microwave-assisted generation and reactivity of aza- and diazafulvenium methides: heterocycles via pericyclic reactions

    Article • Tetrahedron Letters, August 2008, Elsevier

    Teresa Pinho e Melo, Maria Isabel Soares

  209. New approach to exclusive formation of both enantiomers of β-amino acid derivatives

    Article • Tetrahedron, August 2008, Elsevier

    Teresa Pinho e Melo

  210. Chemistry of Diazafulvenium Methides in the Synthesis of Functionalized Pyrazoles.

    Article • ChemInform, October 2007, Wiley

    Teresa Pinho e Melo

  211. “Higher-Order” Azomethine Ylides in the Synthesis of Functionalized Pyrroles and 5-Oxo-5H-pyrrolizines.

    Article • ChemInform, June 2007, Wiley

    Teresa Pinho e Melo

  212. Hexahydro-pyrrolo[1′,2′,5′:3,4,5]thiazolo[3,4-c]oxazol-1-ones: New Chiral Tricyclic L-Cysteine and D-Penicillamine Derivatives.

    Article • ChemInform, May 2007, Wiley

    Teresa Pinho e Melo

  213. Chemistry of Diazafulvenium Methides in the Synthesis of Functionalized Pyrazoles

    Article • The Journal of Organic Chemistry, May 2007, American Chemical Society (ACS)

    Teresa Pinho e Melo, Maria Isabel Soares

  214. Substituent effects on the photolysis of methyl 2-carboxylate substituted aliphatic 2H-azirines

    Article • Journal of Molecular Structure, May 2007, Elsevier

    Teresa Pinho e Melo

  215. Exploiting Azafulvenium Methides Chemistry

    Article • ChemInform, March 2007, Wiley

    Teresa Pinho e Melo

  216. ‘Higher-order’ azomethine ylides in the synthesis of functionalized pyrroles and 5-oxo-5H-pyrrolizines

    Article • Tetrahedron, February 2007, Elsevier

    Teresa Pinho e Melo, Maria Isabel Soares

  217. Intermolecular Cycloaddition of Nonstabilized Azomethine Ylides Generated from 1,3-Thiazolidine-4-carboxylic Acids: Synthesis of 5,7a-Dihydro-1H,3H-pyrrolo[1,2-c]thiazoles.

    Article • ChemInform, January 2007, Wiley

    Teresa Pinho e Melo

  218. Espectroscopia de ressonância magnética nuclear

    Article • January 2007, Coimbra University Press

    Teresa Pinho e Melo

  219. Hexahydro-Pyrrolo[1,2,5:3,4,5]Thiazolo[3,4-c]Oxazol-1-ones: New Chiral Tricyclic L-Cysteine and D-Penicillamine Derivatives

    Article • Letters in Organic Chemistry, November 2006, Bentham Science Publishers

    Teresa Pinho e Melo, Antonio Rocha Gonsalves

  220. Conjugated Azomethine Ylides

    Article • ChemInform, October 2006, Wiley

    Teresa Pinho e Melo

  221. Intermolecular cycloaddition of nonstabilized azomethine ylides generated from 1,3-thiazolidine-4-carboxylic acids: synthesis of 5,7a-dihydro-1H,3H-pyrrolo[1,2-c]thiazoles

    Article • Tetrahedron, October 2006, Elsevier

    Teresa Pinho e Melo, Antonio Rocha Gonsalves

  222. Methyl 3-Methyl-2H-azirine-2-carboxylate Photochemistry Studied by Matrix-isolation FTIR and DFT Calculations

    Article • The Journal of Physical Chemistry A, August 2006, American Chemical Society (ACS)

    Teresa Pinho e Melo

  223. 1,3-Dipolar cycloaddition of azomethine ylides generated from aziridines in supercritical carbon dioxide

    Article • Tetrahedron Letters, July 2006, Elsevier

    Teresa Pinho e Melo

  224. Unusual Photochemical C−N Bond Cleavage in the Novel Methyl 2-Chloro-3-methyl-2H-azirine-2-carboxylate

    Article • The Journal of Physical Chemistry A, June 2006, American Chemical Society (ACS)

    Teresa Pinho e Melo

  225. Conjugated Azomethine Ylides

    Article • European Journal of Organic Chemistry, June 2006, Wiley

    Teresa Pinho e Melo

  226. Conformational Behavior of Dimethyl 5-Methyl-1H,3H-pyrrolo[1,2-c][1,3]thiazole-6,7-dicarboxylate 2,2-Dioxide Isolated in Low-Temperature Matrixes

    Article • The Journal of Physical Chemistry A, May 2006, American Chemical Society (ACS)

    Teresa Pinho e Melo, Maria Isabel Soares

  227. Exploiting azafulvenium methides chemistry

    Article • ARKIVOC, January 2006, University of Michigan Library

    Teresa Pinho e Melo

  228. New chemistry of diazafulvenium methides: one way to pyrazoles

    Article • Tetrahedron Letters, January 2006, Elsevier

    Teresa Pinho e Melo, Maria Isabel Soares, Antonio Rocha Gonsalves

  229. Synthesis of Chiral Thiazolo[3,4-a]pyrazine-5,8-diones

    Article • Heterocycles, January 2006, Japan Institute of Heterocyclic Chemistry

    Teresa Pinho e Melo, Antonio Rocha Gonsalves

  230. N-Vinyl- and C-Vinylpyrroles from Azafulvenium Methides. Flash Vacuum Pyrolysis Route to 5-Oxo-5H-pyrrolizines and 1-Azabenzo[f]azulenes.

    Article • ChemInform, December 2005, Wiley

    Teresa Pinho e Melo

  231. 1,3-Thiazolidine-4-carboxylic Acids as Building Blocks in Organic Synthesis

    Article • ChemInform, November 2005, Wiley

    Teresa Pinho e Melo

  232. On the photophysical behaviour of 4-halo-5-phenylisoxazoles

    Article • Chemical Physics Letters, October 2005, Elsevier

    Hugh Burrows, Teresa Pinho e Melo, Antonio Rocha Gonsalves

  233. Recent Advances on the Synthesis and Reactivity of Isoxazoles

    Article • ChemInform, September 2005, Wiley

    Teresa Pinho e Melo

  234. N-Vinyl- and C-Vinylpyrroles from Azafulvenium Methides. Flash Vacuum Pyrolysis Route to 5-Oxo-5H-pyrrolizines and 1-Azabenzo[f]azulenes

    Article • The Journal of Organic Chemistry, July 2005, American Chemical Society (ACS)

    Teresa Pinho e Melo, Maria Isabel Soares, Antonio Rocha Gonsalves

  235. Recent Advances on the Synthesis and Reactivity of Isoxazoles

    Article • Current Organic Chemistry, July 2005, Bentham Science Publishers

    Teresa Pinho e Melo

  236. Novel Asymmetric Wittig Reaction: Synthesis of Chiral Allenic Esters.

    Article • ChemInform, March 2005, Wiley

    Teresa Pinho e Melo

  237. Exploiting 2-Halo-2H-azirine Chemistry

    Article • ChemInform, February 2005, Wiley

    Teresa Pinho e Melo

  238. Generation and Reactivity of 3-Carbethoxy-5-phenyl-5H,7H-thiazolo[3,4-c]oxazol-4-ium-1-olate.

    Article • ChemInform, December 2004, Wiley

    Teresa Pinho e Melo

  239. Novel Asymmetric Wittig Reaction: Synthesis of Chiral Allenic Esters

    Article • European Journal of Organic Chemistry, November 2004, Wiley

    Teresa Pinho e Melo, Antonio Rocha Gonsalves

  240. Reactivity of Azafulvenium Methides Derived from Pyrrolo[1,2-c]thiazole-2,2-dioxides: Synthesis of Functionalized Pyrroles.

    Article • ChemInform, August 2004, Wiley

    Teresa Pinho e Melo

  241. Synthesis of Tricyclic Isoindoles and Thiazolo[3,2-c][1,3]benzoxazines.

    Article • ChemInform, August 2004, Wiley

    Teresa Pinho e Melo

  242. Exploiting 2-Halo-2H-Azirine Chemistry

    Article • Current Organic Synthesis, July 2004, Bentham Science Publishers

    Teresa Pinho e Melo

  243. Generation and reactivity of 3‐carbethoxy‐5‐phenyl‐5H,7H‐thiazolo[3,4‐c]oxazol‐4‐ium‐1‐olate

    Article • Journal of Heterocyclic Chemistry, July 2004, Wiley

    Teresa Pinho e Melo

  244. Reactivity of azafulvenium methides derived from pyrrolo[1,2-c]thiazole-2,2-dioxides: synthesis of functionalised pyrroles

    Article • Tetrahedron Letters, May 2004, Elsevier

    Teresa Pinho e Melo, Maria Isabel Soares, Antonio Rocha Gonsalves

  245. Synthesis of tricyclic isoindoles and thiazolo[3,2-c][1,3]benzoxazines

    Article • Tetrahedron, April 2004, Elsevier

    Teresa Pinho e Melo, Antonio Rocha Gonsalves

  246. Corrigendum to ‘Contribution to the synthesis of chiral allenic esters’

    Article • Tetrahedron Letters, March 2004, Elsevier

    Antonio Rocha Gonsalves, Teresa Pinho e Melo

  247. Synthesis of Novel Tricyclic Isoindole Derivatives.

    Article • ChemInform, February 2004, Wiley

    Teresa Pinho e Melo

  248. 2H-Azirines as Dipolarophiles.

    Article • ChemInform, December 2003, Wiley

    Teresa Pinho e Melo

  249. Synthesis of novel tricyclic isoindole derivatives

    Article • Tetrahedron Letters, November 2003, Elsevier

    Teresa Pinho e Melo, Antonio Rocha Gonsalves

  250. 2H-Azirines as dipolarophiles

    Article • Tetrahedron Letters, August 2003, Elsevier

    Teresa Pinho e Melo, Antonio Rocha Gonsalves

  251. Contribution to the synthesis of chiral allenic esters

    Article • Tetrahedron Letters, August 2003, Elsevier

    Teresa Pinho e Melo, Antonio Rocha Gonsalves

  252. Reactivity of 2-Halo-2H-azirines. Part 3. Dehalogenation of 2-Halo-2H-azirine-2-carboxylates.

    Article • ChemInform, July 2003, Wiley

    Teresa Pinho e Melo

  253. Reactivity of 2-halo-2H-azirines. Part 3: Dehalogenation of 2-halo-2H-azirine-2-carboxylates

    Article • Tetrahedron, March 2003, Elsevier

    Teresa Pinho e Melo, Antonio Rocha Gonsalves

  254. Cycloaddition reactions of 3-aryl-5-phenyl-5H,7H-thiazolo[3,4-c]oxazol-4-ium-1-olates

    Article • Tetrahedron, June 2002, Elsevier

    Teresa Pinho e Melo, Antonio Rocha Gonsalves

  255. Synthesis of Chiral Pyrrolo[1,2-c]thiazoles via Intramolecular Dipolar Cycloaddition of Münchnones:  An Interesting Rearrangement to Pyrrolo[1,2-c]thiazines

    Article • The Journal of Organic Chemistry, May 2002, American Chemical Society (ACS)

    Teresa Pinho e Melo, Maria Isabel Soares, Antonio Rocha Gonsalves

  256. Reactivity of 2-Halo-2H-azirines. Part II. Thermal Ring Expansion Reactions: Synthesis of 4-Haloisoxazoles

    Article • Synthesis, January 2002, Thieme Publishing Group

    Teresa Pinho e Melo

  257. Reactivity of 2-Halo-2H-azirines. 1. Reactions with Nucleophiles

    Article • The Journal of Organic Chemistry, December 2001, American Chemical Society (ACS)

    Teresa Pinho e Melo, Antonio Rocha Gonsalves

  258. Synthesis of 2-halo-2H-azirines

    Article • Tetrahedron, July 2001, Elsevier

    Teresa Pinho e Melo, Antonio Rocha Gonsalves

  259. ChemInform Abstract: Synthesis and Reactivity of 2-Halo-2H-azirines Towards Nucleophiles.

    Article • ChemInform, November 2000, Wiley

    Teresa Pinho e Melo

  260. Synthesis of 5-Substituted a,b-Unsaturated g-Lactams from N-Sulfinyl Azadienes by Iron-mediated Reaction Cascades and Palladiumcatalyzed Cyclocarbonylation Strategies

    Article • September 2000, MDPI AG

    Teresa Pinho e Melo

  261. Synthesis and reactivity of 2-halo-2H-azirines towards nucleophiles

    Article • Tetrahedron Letters, September 2000, Elsevier

    Teresa Pinho e Melo

  262. Intermolecular Dipolar Cycloaddition Reactions of 5H,7H-Thiazolo[3,4-c]oxazol-4-ium-1-olates

    Article • Tetrahedron, May 2000, Elsevier

    Teresa Pinho e Melo

  263. A New Route to Cross-Conjugated Bis(enamines) and an Unusual Reaction with DDQ

    Article • The Journal of Organic Chemistry, August 1999, American Chemical Society (ACS)

    Teresa Pinho e Melo, Antonio Rocha Gonsalves

  264. Reactivity of a-Oxophosphonium Ylides: A Contribution to the Mechanistics

    Article • Molecules, July 1999, MDPI AG

    Teresa Pinho e Melo

  265. (R)-Spiro[(2R)-N-acetyl-2-phenyl-1,3-thiazolidine-4,3'-(3a'R,6a'S)-5',6a'-dimethyl-3a',-6a'-dihydro-3H-furo[2,3-b]furan-2-one]

    Article • Acta Crystallographica Section C Crystal Structure Communications, July 1999, International Union of Crystallography

    Teresa Pinho e Melo

  266. Synthesis of 2-halo-2H-azirines from phosphorus ylides

    Article • Tetrahedron Letters, January 1999, Elsevier

    Teresa Pinho e Melo, Antonio Rocha Gonsalves

  267. Intramolecular dipolar cycloaddition reaction of 5H,7H-thiazolo[3,4-c]oxazol-4-ium-1-olates: synthesis of chiral 1H-pyrrolo[1,2-c]thiazole derivatives

    Article • Journal of the Chemical Society Perkin Transactions 1, January 1999, Royal Society of Chemistry

    Teresa Pinho e Melo

  268. Divinylamines: Synthesis and Conversion into Azepine Derivatives

    Article • November 1998, MDPI AG

    Teresa Pinho e Melo

  269. Diels−Alder Reactions of Acyclic 2-Azadienes:  A Semiempirical Molecular Orbital Study

    Article • The Journal of Organic Chemistry, July 1998, American Chemical Society (ACS)

    Teresa Pinho e Melo

  270. Methyl 2-(2-Methoxyphenyl)-2,3,3a,4,6,6a-hexahydro-1H-thieno[3,4-b]pyrrole-6a-carboxylate

    Article • Acta Crystallographica Section C Crystal Structure Communications, June 1998, International Union of Crystallography

    Teresa Pinho e Melo

  271. Intramolecular Cycloaddition of Imines of Cysteine Derivatives

    Article • Molecules, February 1998, MDPI AG

    Teresa Pinho e Melo

  272. The Reaction of an α-Oxophosphonium Ylide with Halogens: 2,3-Disubstituted Diethyl Butenedioates from Diethyl 2-Oxo-3-triphenylphosphoranylidenebutanedioate

    Article • Synthesis, June 1997, Thieme Publishing Group

    Teresa Pinho e Melo

  273. The use of 2-azadienes in the Diels-Alder reaction

    Article • Pure and Applied Chemistry, January 1996, De Gruyter

    Teresa Pinho e Melo

  274. Attempted intramolecular diets-alder reactions of 2-azadienes: Alternative dimerisation and dipolar cycloaddition pathways

    Article • Tetrahedron, November 1995, Elsevier

    Teresa Pinho e Melo, Antonio Rocha Gonsalves

  275. Diels-Alder reactions of 2-azadienes derived from cysteine and serine methyl esters and aldehydes

    Article • Tetrahedron, January 1994, Elsevier

    Teresa Pinho e Melo, Antonio Rocha Gonsalves

  276. Aza Cope rearrangement of schiff bases derived from endo-norbornen-5-amines

    Article • Tetrahedron Letters, October 1993, Elsevier

    Teresa Pinho e Melo, Antonio Rocha Gonsalves

  277. Diels-alder reactions of 2-azadienes derived from cysteine methyl ester

    Article • Tetrahedron Letters, June 1993, Elsevier

    Teresa Pinho e Melo, Antonio Rocha Gonsalves

  278. Diels-alder reactions of 1,2,4-triazines with cyclic vinyl ethers

    Article • Tetrahedron, June 1993, Elsevier

    Teresa Pinho e Melo, Antonio Rocha Gonsalves

  279. Synthesis of isoquinolines by cycloaddition of arynes to 1,2,4-triazines

    Article • Tetrahedron, January 1992, Elsevier

    Teresa Pinho e Melo, Antonio Rocha Gonsalves