Dr Roland Wohlgemuth
Sigma-Aldrich, Member of Merck Group
Other, Life Sciences
Switzerland
My co-authors include
Prof. Uwe T Bornscheuer
Dr Eduardo García-Junceda
Professor Krist V. Gernaey
My Publications
Biocatalysis in the Swiss Manufacturing Environment
Catalysts
December 2020
Key advances in biocatalytic phosphorylations in the last two decades – Biocatalytic sy...
Biotechnology Journal
November 2020
Bioeconomy Moving forward Step by Step – A Global Journey
New Biotechnology
November 2020
Molecular and Engineering Aspects of Biocatalysis
Biotechnology Journal
November 2020
Corrigendum: Enzymatic Synthesis of 2-Keto-3-Deoxy-6-Phosphogluconate by the 6-Phosphog...
Frontiers in Bioengineering and Biotechnology
July 2020
Building Bridges between Biotechnology and Chemistry – Oreste Ghisalba's Pioneering Act...
CHIMIA International Journal for Chemistry
May 2020
A combined experimental and modelling approach for the Weimberg pathway optimisation
Nature Communications
February 2020
Efficient biocatalytic synthesis of D-tagatose 1,6-diphosphate by LacC-catalysed phosph...
Biocatalysis and Biotransformation
July 2019
Facile synthesis of D-xylulose-5-phosphate and L-xylulose-5-phosphate by xylulokinase-c...
Biocatalysis and Biotransformation
June 2019
Bioeconomy for sustainable development
Biotechnology Journal
May 2019
From lab to large scale – Industrial biocatalysis from an SIBC perspective
New Biotechnology
October 2018
The challenges and opportunities of cascading enzymatic microreactors
New Biotechnology
October 2018
Discovering novel hydrolases from hot environments
Biotechnology Advances
September 2018
An empirical analysis of enzyme function reporting for experimental reproducibility: Mi...
Biophysical Chemistry
August 2018
Front Cover: Phosphorylation Catalyzed by Dihydroxyacetone Kinase (Eur. J. Org. Chem. /...
European Journal of Organic Chemistry
June 2018
Biocatalytic reaction systems for the synthesis of metabolites.
Biotechnology Journal
May 2018
Recombinant AroL-Catalyzed Phosphorylation for the Efficient Synthesis of Shikimic Acid...
Biotechnology Journal
May 2018
Phosphorylation Catalyzed by Dihydroxyacetone Kinase
European Journal of Organic Chemistry
May 2018
STRENDA DB: enabling the validation and sharing of enzyme kinetics data
FEBS Journal
March 2018
Mechanistic and kinetics elucidation of Mg2+/ATP molar ratio effect on glycerol kinase
Molecular Catalysis
February 2018
Perspectives on bioeconomy
New Biotechnology
January 2018
Preface to the special issue bioeconomy
New Biotechnology
January 2018
Enzymatic synthesis of chiral amino-alcohols by coupling transketolase and transaminase...
Biotechnology and Bioengineering
November 2017
Biocatalytic Process Design and Reaction Engineering
Chemical and Biochemical Engineering Quarterly
July 2017
Biocatalytic Asymmetric Phosphorylation Catalyzed by Recombinant Glycerate-2-Kinase
ChemBioChem
June 2017
Conscious coupling: The challenges and opportunities of cascading enzymatic microreactors
Biotechnology Journal
May 2017
Biocatalytic Phosphorylations of Metabolites: Past, Present, and Future
Trends in Biotechnology
May 2017
Real-time pH monitoring of industrially relevant enzymatic reactions in a microfluidic ...
Biotechnology Journal
February 2017
Bioreaction Engineering Leading to Efficient Synthesis of L-Glyceraldehyd-3-Phosphate
Biotechnology Journal
January 2017
Inside Cover: Synthesis of N ω -Phospho-l -arginine by Biocatal...
ChemCatChem
January 2017
Biocatalytic asymmetric Michael addition reaction
RSC Advances
January 2017
Synthesis ofNω-Phospho-l-arginine by Biocatalytic Phosphorylation ofl-Arginine
ChemCatChem
December 2016
A generic model-based methodology for quantification of mass transfer limitations in mi...
Chemical Engineering Journal
September 2016
Biocatalytic Phosphorylation of Metabolites
August 2016
Exploitation of novel epoxide hydrolases from metagenomic libraries in the solvent-free...
New Biotechnology
July 2016
One-pot enzymatic reaction sequence for the syntheses of d-glyceraldehyde 3-phosphate a...
Journal of Molecular Catalysis B Enzymatic
February 2016
Highly efficient and scalable chemoenzymatic syntheses of (R)- and (S)-lactaldehydes
Reaction Chemistry & Engineering
January 2016
Efficient Epoxide Hydrolase Catalyzed Resolutions of (+)- and (−)-cis/trans-Limonene Ox...
ChemCatChem
August 2015
Discovery and characterization of thermophilic limonene-1,2-epoxide hydrolases from hot...
FEBS Journal
June 2015
Economic Considerations for Selecting an Amine Donor in Biocatalytic Transamination
Organic Process Research & Development
June 2015
Microscale technology and biocatalytic processes: opportunities and challenges for synt...
Trends in Biotechnology
May 2015
Straightforward Synthesis of Terminally Phosphorylated L -Sugars via Multienzymatic Ca...
Advanced Synthesis & Catalysis
April 2015
One-step synthesis of 2-keto-3-deoxy-d-gluconate by biocatalytic dehydration of d-gluco...
Journal of Biotechnology
December 2014
Characterization of a phosphotriesterase-like lactonase from the hyperthermoacidophilic...
Journal of Biotechnology
November 2014
Dihydroxyacetone-catalyzed phosphorylation
New Biotechnology
July 2014
Chemical and enzymatic methodologies for the synthesis of enantiomerically pure glycera...
Carbohydrate Research
May 2014
Biocatalytic asymmetric phosphorylation of mevalonate
RSC Advances
January 2014
7.04 Oxidation by Microbial Methods
January 2014
Microfluidic multi-input reactor for biocatalytic synthesis using transketolase
Journal of Molecular Catalysis B Enzymatic
November 2013
Development of Sustainable Biocatalytic Reduction Processes for Organic Chemists
August 2013
Laccase-mediated synthesis of 2-methoxy-3-methyl-5-(alkylamino)- and 3-methyl-2,5-bis(a...
Journal of Molecular Catalysis B Enzymatic
June 2013
The use of enzymes in organic synthesis and the life sciences: perspectives from the Sw...
Catalysis Science & Technology
January 2013
Desymmetrization of cbz-serinol catalyzed by crude pig pancreatic lipase reveals action...
Journal of Molecular Catalysis B Enzymatic
January 2013
One-Pot Cascade Reactions using Fructose-6-phosphate Aldolase: Efficient Synthesis of D...
Advanced Synthesis & Catalysis
June 2012
Modular microfluidic reactor and inline filtration system for the biocatalytic synthesi...
Journal of Molecular Catalysis B Enzymatic
May 2012
Epoxide Hydrolases and their Application in Organic Synthesis
Current Organic Chemistry
February 2012
Industrial biotechnology – past, present and future
New Biotechnology
January 2012
ChemInform Abstract: Large-Scale Applications of Hydrolases in Biocatalytic Asymmetric ...
ChemInform
July 2011
Green Production of Fine Chemicals by Isolated Enzymes
April 2011
Product Recovery
January 2011
Biocatalysis—key to sustainable industrial chemistry
Current Opinion in Biotechnology
December 2010
Swiss Industrial Biocatalysis Consortium (SIBC)
CHIMIA International Journal for Chemistry
November 2010
Biocatalytic Routes to Nature's Chemicals
Journal of Biotechnology
November 2010
Applications of Baeyer-Villiger Monooxygenases in Organic Synthesis
Current Organic Chemistry
October 2010
High-Yield Biocatalytic Amination Reactions in Organic Synthesis
Current Organic Chemistry
October 2010
Large-Scale Applications of Hydrolases in Biocatalytic Asymmetric Synthesis
June 2010
Asymmetric Baeyer-Villiger Reactions Using Whole-Cell Biocatalysts
June 2010
ChemInform Abstract: C2-Ketol Elongation by Transketolase-Catalyzed Asymmetric Synthesis
ChemInform
June 2010
Asymmetric biocatalysis with microbial enzymes and cells
Current Opinion in Microbiology
June 2010
Industrial Biotechnology in the Chemical and Pharmaceutical Industries
April 2010
Industrial Biotransformation
April 2010
Guidelines for reporting of biocatalytic reactions
Trends in Biotechnology
April 2010
Characterization of a whole-cell catalyst co-expressing glycerol dehydrogenase and gluc...
Biotechnology and Bioengineering
March 2010
Transketolases
December 2009
C2-Ketol elongation by transketolase-catalyzed asymmetric synthesis
Journal of Molecular Catalysis B Enzymatic
November 2009
Modeling and Simulation of Burr Formation: State-of-the-Art and Future Trends
October 2009
Tools and ingredients for the biocatalytic synthesis of metabolites
Biotechnology Journal
September 2009
Synthesis of pyridoxamine 5′-phosphate using an MBA:pyruvate transaminase as biocatalyst
Journal of Molecular Catalysis B Enzymatic
August 2009
Characterisation of a Recombinant NADP-Dependent Glycerol Dehydrogenase from Gluconobac...
ChemBioChem
July 2009
Influence of pH on the expression of a recombinant epoxide hydrolase in Aspergillus niger
Biotechnology Journal
May 2009
The locks and keys to industrial biotechnology
New Biotechnology
April 2009
Preparative-scale separation by simulated moving bed chromatography of biocatalytically...
New Biotechnology
April 2009
The First 200-L Scale Asymmetric Baeyer−Villiger Oxidation Using a Whole-Cell Biocatalyst
Organic Process Research & Development
July 2008
ChemInform Abstract: Interfacing Biocatalysis and Organic Synthesis
ChemInform
June 2008
Characterization of enzymatic D-xylulose 5-phosphate synthesis
Biotechnology and Bioengineering
April 2008
Preparative scale Baeyer–Villiger biooxidation at high concentration using recombinant ...
Nature Protocols
March 2008
Process analysis of macrotetrolide biosynthesis during fermentation by means of direct ...
Biotechnology Journal
February 2008
Production of epoxide hydrolases in batch fermentations of Botryosphaeria rhodina
Journal of Industrial Microbiology & Biotechnology
January 2008
Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell ...
Nature Medicine
January 2008
Tools and ingredients for the biocatalytic synthesis of carbohydrates and glycoconjugates
Biocatalysis and Biotransformation
January 2008
Interfacing biocatalysis and organic synthesis
Journal of Chemical Technology & Biotechnology
January 2007
Chemoenzymatic synthesis of chiral carboxylic acids via nitriles
Journal of Chemical Technology & Biotechnology
January 2007
Amino acid oxidase-catalysed resolution and Pictet–Spengler reaction towards chiral and...
Journal of Chemical Technology & Biotechnology
January 2007
Modular and scalable biocatalytic tools for practical safety, health and environmental ...
Biocatalysis and Biotransformation
January 2007
Tools for Selective Enzyme Reaction Steps in the Synthesis of Laboratory Chemicals
Engineering in Life Sciences
December 2006
Semiquantitative Process Screening for the Biocatalytic Synthesis ofd-Xylulose-5-phosphate
Organic Process Research & Development
May 2006
Selective hydrolysis of the nitrile group of cis-dihydrodiols from aromatic nitriles
Journal of Molecular Catalysis B Enzymatic
February 2006
On the influence of oxygen and cell concentration in an SFPR whole cell biocatalytic Ba...
Biotechnology and Bioengineering
January 2006
Development, Production, and Application of Recombinant Yeast Biocatalysts in Organic S...
CHIMIA International Journal for Chemistry
October 2005
Recombinant Chlorobenzene Dioxygenase fromPseudomonas sp. P51: A Biocatalyst for Regios...
Advanced Synthesis & Catalysis
June 2005
Microbial transformations 59: First kilogram scale asymmetric microbial Baeyer-Villiger...
Biotechnology and Bioengineering
January 2005
Microbiological Transformations 57. Facile and Efficient Resin-Based in Situ SFPR Prepa...
Organic Letters
June 2004
The Eleventh European Congress on Biotechnology, Basel, Switzerland, August 26, 2003
Biocatalysis and Biotransformation
March 2004
Microbial Transformations, 56. Preparative Scale Asymmetric Baeyer–Villiger Oxidation u...
Advanced Synthesis & Catalysis
February 2004
Towards large-scale synthetic applications of Baeyer-Villiger monooxygenases
Trends in Biotechnology
July 2003
Reactor Operation and Scale-Up of Whole Cell Baeyer-Villiger Catalyzed Lactone Synthesis
Biotechnology Progress
October 2002
Environmental influences on the photooxidation of manganese by a zinc porphyrin sensitizer
Proceedings of the National Academy of Sciences
August 1982
The headgroup conformation of phospholipids in membranes
The Journal of Membrane Biology
June 1981
Bilayers of phosphatidylglycerol. A deuterium and phosphorus nuclear magnetic resonance...
Biochemistry
July 1980
Orientation and flexibility of the choline head group in phosphatidylcholine bilayers
Biochimica et Biophysica Acta (BBA) - Biomembranes
June 1977
The electronic evaluation of fetal heart rate
American Journal of Obstetrics and Gynecology
February 1961
Biocatalytic Asymmetric Oxidations with Oxygen
Large-Scale Applications of Biocatalysis in the Asymmetric Synthesis of Laboratory Chem...
CHAPTER 3. Biocatalytic Synthesis of Small Molecules – Past, Present and Future