All Stories

  1. Flow-informed clustering of bioreactor volumes to build CFD-based compartment models
  2. High-Performance C++ and Julia solvers in CADET for weakly and strongly coupled continuous chromatography problems
  3. Liquid biofuels from waste: Modelling thermodynamic limits of the anaerobic biorefinery
  4. The Potential of Fermentation-Based Processing on Protein Modification: A Review
  5. A systematic screening of neural network‐based hybrid models of adsorption in chromatography processes
  6. Transfer learning for quantitative image analysis of biosolids
  7. Beyond ChatGMP: Improving LLM generation through user preferences
  8. Closing the loop: customized coding courses and chatbots embedded in a virtual lab to teach bioprocesses
  9. Diagnosing Faults in Wastewater Systems: A Data-Driven Approach to Handle Imbalanced Big Data
  10. Digital Shadow of a Pilot Scale Packed Batch Distillation Column for Real-Time Operator Training- and Support
  11. A teaching application of large language models
  12. Quantifying, predicting, and mitigating nitrous oxide emissions in a full-scale partial nitritation/anammox reactor treating reject water
  13. Dynamically predicting nitrous oxide emissions in a full-scale industrial activated sludge reactor under multiple aeration patterns and COD/N ratios
  14. Advancing regulatory dialogue: In silico models for improved vaccine biomanufacturing - an expert meeting report
  15. Holistic assessment of management strategies and technological solutions handling anaerobic digester supernatants in wastewater treatment plants
  16. CFD-guided scaling of Pseudomonas putida fermentation
  17. CADET-Julia: Efficient and versatile, open-source simulator for batch chromatography in Julia
  18. Trends der Entwicklung von digitalen Zwillingen für die Bioproduktionsindustrie
  19. Navigating industry 4.0 and 5.0: the role of hybrid modelling in (bio)chemical engineering’s digital transition
  20. Towards Education 4.0: The role of Large Language Models as virtual tutors in chemical engineering
  21. Isobutyric and n-butyric acid production from H2 and CO2 by Clostridium luticellarii in a hollow fiber membrane biofilm reactor: Reactor operation and process modelling
  22. Production of phosphate biofertilizers as a booster for the techno-economic and environmental performance of a first-generation sugarcane ethanol and sugar biorefinery
  23. Hybrid Modeling for On-Line Fermentation Optimization and Scale-Up: A Review
  24. Making waves: Power-to-X for the Water Resource Recovery Facilities of the future
  25. Data fusion of Raman spectra in MSPC for fault detection and diagnosis in pharmaceutical manufacturing
  26. Modernizing non-classical protein crystallization through industry 4.0: Advanced monitoring and modelling utilizing process analytical technology
  27. Raman spectroscopy and one‐dimensional convolutional neural network modeling as a real‐time monitoring tool for in vitro transaminase‐catalyzed synthesis of a pharmaceutically relevant amine precursor
  28. Accelerating vaccine manufacturing development through model-based approaches: current advances and future opportunities
  29. Preface of the 2nd International Electronic Conference on Processes (ECP 2023)
  30. Nitrous oxide emissions from two full-scale membrane-aerated biofilm reactors
  31. Water innovation in industrial symbiosis - A global review
  32. A process systems engineering view of environmental impact assessment in renewable and sustainable energy production: Status and perspectives
  33. A Process Monitoring Framework for Imbalanced Big Data: A Wastewater Treatment Plant Case Study
  34. Big Data Analytics for Advanced Fault Detection in Wastewater Treatment Plants
  35. Discontinuous Galerkin spectral element method for continuous chromatography: Application to the Lumped Rate Model without pores
  36. FermentAI: Large Language Models in Chemical Engineering Education for Learning Fermentation Processes
  37. Overcoming the challenges of dynamic systems in steady-state simulations: the use of meta-modeling as a surrogate for complex kinetic models
  38. Towards Modelling of an Industrial Aspergillus oryzae Aerobic Fed-batch Fermentation Process – Process Characterization Across Scales
  39. Shortcut design method for multicomponent gradient simulated moving beds
  40. Statement of Peer Review
  41. SPyCE: A structured and tailored series of Python courses for (bio)chemical engineers
  42. A data analytics pipeline to optimize polymer dose strategy in a semi-continuous multi-feed dewatering system
  43. Modelling of industrial-scale bioreactors using the particle lifeline approach
  44. Life cycle assessment of an integrated xylitol biorefinery with value-added co-products
  45. Digital tools in chemical engineering education: The needs and the desires
  46. Modelling and Economic Optimal Control for a Laboratory-scale Continuous Stirred Tank Reactor for Single-cell Protein Production
  47. Designing a fault detection classifier framework for an industrial dynamic ultrafiltration membrane process using wavelet-based feature analysis
  48. Transforming data into actionable knowledge for fault detection, diagnosis and prognosis in urban wastewater systems with AI techniques: A mini-review
  49. Integrated capacity and production planning in the pharmaceutical supply chain: Framework and models
  50. Modelling the impacts of operational conditions on the performance of a full-scale membrane aerated biofilm reactor
  51. The effects of low oxidation-reduction potential on the performance of full-scale hybrid membrane-aerated biofilm reactors
  52. Design of multi-component gradient SMBs
  53. Digital Twins in Pilot Scale Fermentation: Non-Linear State Estimation for Improving Induction Timing
  54. Handheld FTIR outperforms total organic carbon swab in pharmaceutical cleaning validation
  55. Integrating Python in the (bio)chemical engineering curriculum: challenges and opportunities
  56. NyctiDB: A non-relational bioprocesses modeling database supported by an ontology
  57. Digital models in biotechnology: Towards multi-scale integration and implementation
  58. From Paper to web: Students as partners for virtual laboratories in (Bio)chemical engineering education
  59. Prediction of mass and volumetric flows in a full-scale industrial waste treatment plant
  60. Data-based dynamic compartment model: Modeling ofE. colifed-batch fermentation in a 600 m3 bubble column
  61. Economic, technical, and environmental evaluation of retrofitting scenarios in a full-scale industrial wastewater treatment system
  62. To be fAIr: ethical and fair application of artificial intelligence in virtual laboratories
  63. Corrigendum to ‘Economic and environmental analysis of bio-succinic acid production: From established processes to a new continuous fermentation approach with in-situ electrolytic extraction’ [Chemical Engineering Research and Design Volume 179, March ...
  64. Rendered-Protein Hydrolysates as a Low-Cost Nitrogen Source for the Fungal Biotransformation of 5-Hydroxymethylfurfural
  65. Shaping an Open Microbiome for Butanol Production through Process Control
  66. Optimal Conversion of Organic Wastes to Value-Added Products: Toward a Sustainable Integrated Biorefinery in Denmark
  67. Sampling Error of TOC swab in Pharmaceutical Cleaning Verification
  68. Mathematical Modeling of the Electro-Oxidation Process
  69. Plant-wide assessment of alternative activated sludge configurations for biological nutrient removal under uncertain influent characteristics
  70. Benchmarking strategies to control GHG production and emissions
  71. Digitalisation in chemical engineering: Industrial needs, academic best practice, and curriculum limitations
  72. Economic and environmental analysis of bio-succinic acid production: From established processes to a new continuous fermentation approach with in-situ electrolytic extraction
  73. Conceptual Process Design of an Integrated Xylitol Biorefinery With Value-Added Co-Products
  74. Model development for the optimization of operational conditions of the pretreatment of wheat straw
  75. Soft‐sensors application for automated feeding control in high‐throughput mammalian cell cultures
  76. Plant wide modelling of a full-scale industrial water treatment system
  77. A combinatorial tool for monitoring flocculation processes: Using non-invasive measurements and hybrid deep learning assisted modelling
  78. Computational fluid dynamics modelling of hydrodynamics, mixing and oxygen transfer in industrial bioreactors with Newtonian broths
  79. Digital Twin of a pilot-scale bio-production setup
  80. Dynamic Modeling and Control of a Continuous Biopharmaceutical Manufacturing Plant
  81. Educational Computer-Aided Tools Towards Industry 4.0: Recommendations and BioVL
  82. Forecasting Operational Conditions: A case-study from dewatering of biomass at an industrial wastewater treatment plant
  83. Holistic Capacity Management and Production Planning in the Pharmaceutical Supply Chain
  84. LCA modelling as a decision-tool for experimental design: the case of extraction of astaxanthin from crab waste
  85. Modeling and Simulation of Upstream and Downstream Processes for Monoclonal Antibody Production
  86. On-line monitoring of process parameters during fermentation
  87. Pilot Plant 4.0: A Review of Digitalization Efforts of the Chemical and Biochemical Engineering Department at the Technical University of Denmark (DTU)
  88. Sensitivity Analysis and Risk Assessment for the In-Silico Design and Use of Optimized Cell Factories in a Xylitol Biorefinery
  89. Separation of succinic acid from fermentation broth: Dielectric exclusion, Donnan effect and diffusion as the most influential mass transfer mechanisms
  90. Value Chain Optimization of a Xylitol Biorefinery with Delaunay Triangulation Regression Models
  91. Co-cultivation of a novel Fusarium striatum strain and a xylose consuming Saccharomyces cerevisiae yields an efficient process for simultaneous detoxification and fermentation of lignocellulosic hydrolysates
  92. Fault diagnosis of chemical processes based on joint recurrence quantification analysis
  93. Integration of first-principle models and machine learning in a modeling framework: An application to flocculation
  94. Modelling and control of an integrated high purity methanol distillation configuration
  95. Exceptionally rich keratinolytic enzyme profile found in the rare actinomycetes Amycolatopsis keratiniphila D2T
  96. Characterization of mixing performance in bioreactors using flow-following sensor devices
  97. Techno-economic and environmental impact assessment of biogas production and fertiliser recovery from pelagic Sargassum: A biorefinery concept for Barbados
  98. Mechanisms, status, and challenges of thermal hydrolysis and advanced thermal hydrolysis processes in sewage sludge treatment
  99. Towards Digitalization in Bio-Manufacturing Operations: A Survey on Application of Big Data and Digital Twin Concepts in Denmark
  100. Automated Compartment Model Development Based on Data from Flow-Following Sensor Devices
  101. An easy to use GUI for simulating big data using Tennessee Eastman process
  102. Alone or together? A review on pure and mixed microbial cultures for butanol production
  103. Assessment of alkaline stabilization processes in industrial waste streams using a model-based approach
  104. Development of dynamic compartment models for industrial aerobic fed-batch fermentation processes
  105. Microbial biofilms in biorefinery – Towards a sustainable production of low-value bulk chemicals and fuels
  106. A framework for the development of Pedagogical Process Simulators (P2Si) using explanatory models and gamification
  107. Synergistic optimization framework for the process synthesis and design of biorefineries
  108. Long-term operation assessment of a full-scale membrane-aerated biofilm reactor under Nordic conditions
  109. Particle-Scale Modeling to Understand Liquid Distribution in Twin-Screw Wet Granulation
  110. Model-Based Evaluation of a Data-Driven Control Strategy: Application to Ibuprofen Crystallization
  111. Analysis of the response of the cell membrane of Saccharomyces cerevisiae during the detoxification of common lignocellulosic inhibitors
  112. Digital Twin in biomanufacturing: challenges and opportunities towards its implementation
  113. Simulation-based evaluation of sludge management strategies in a WWTP
  114. Special Issue on “Recent Advances in Population Balance Modeling”
  115. Incremental design of water symbiosis networks with prior knowledge: The case of an industrial park in Kenya
  116. Understanding gradients in industrial bioreactors
  117. An uncertainty-aware hybrid modelling approach using probabilistic machine learning
  118. Implementation of first-principles surface interactions in a hybrid machine learning assisted modelling of flocculation
  119. Modelling and Dynamic Optimization of beer fermentation towards optimal flavor and operation
  120. Programming skills across the (bio)engineering curriculum – a students’ perspective
  121. Sustainable bio-succinic acid production: superstructure optimization, techno-economic, and lifecycle assessment
  122. Towards a Digital Twin: A validated Digital Model of a Pilot Scale Bioreactor producing Green Fluorescent Protein (GFP)
  123. Unsupervised Monitoring of Flocculation Processes based on Recurrence Theory
  124. Why Is Batch Processing Still Dominating the Biologics Landscape? Towards an Integrated Continuous Bioprocessing Alternative
  125. Electrochemical tuning of alcohol oxidase and dehydrogenase catalysis via biosensing towards butanol-1 detection in fermentation media
  126. Stochastic simulation-based superstructure optimization framework for process synthesis and design under uncertainty
  127. Promoting the co-utilisation of glucose and xylose in lignocellulosic ethanol fermentations using a data-driven feed-back controller
  128. Transforming data to information: A parallel hybrid model for real‐time state estimation in lignocellulosic ethanol fermentation
  129. Separation of middle boiling trace compounds by distillation: An investigation of practical implications of complex column arrangements on an industrial methanol distillation case study
  130. Towards smart biomanufacturing: a perspective on recent developments in industrial measurement and monitoring technologies for bio-based production processes
  131. Hybrid machine learning assisted modelling framework for particle processes
  132. The Role of Big Data in Industrial (Bio)chemical Process Operations
  133. Automated Electrochemical Glucose Biosensor Platform as an Efficient Tool Toward On-Line Fermentation Monitoring: Novel Application Approaches and Insights
  134. Towards a digital twin: a hybrid data‐driven and mechanistic digital shadow to forecast the evolution of lignocellulosic fermentation
  135. Dynamic model validation and advanced polymer control for rotating belt filtration as primary treatment of domestic wastewaters
  136. Assessment of the fate of organic micropollutants in novel wastewater treatment plant configurations through an empirical mechanistic model
  137. Design and Application of an Electrochemical Sensor for Ammonium Monitoring in Bioprocesses
  138. Monitoring yeast fermentations by nonlinear infrared technology and chemometrics—understanding process correlations and indirect predictions
  139. A process synthesis tool for WWTP – An application to design sustainable energy recovery facilities
  140. Distinguishing Commercial Beers Using a Solution-Based Sensor Array Derived from Nanoscale Polydiacetylene Vesicles
  141. Application of Organic-Inorganic Hybrids in Chemical Analysis, Bio- and Environmental Monitoring
  142. Modeling and system identification of an unconventional bioreactor used for single cell protein production
  143. Two novel S1 peptidases from Amycolatopsis keratinophila subsp. keratinophila D2T degrading keratinous slaughterhouse by-products
  144. A novel use for an old problem: The Tennessee Eastman challenge process as an activating teaching tool
  145. Resource recovery from waste streams in a water-energy-food nexus perspective: Toward more sustainable food processing
  146. Towards one-step design of tailored enzymatic nanobiosensors
  147. Model-Based Tools for Pharmaceutical Manufacturing Processes
  148. Flow-following sensors for fermentation processes - an overview
  149. Towards the Development of Digital Twins for the Bio-manufacturing Industry
  150. A Hybrid Model Predictive Control Strategy using Neural Network Based Soft Sensors for Particle Processes
  151. An E-learning Bot for Bioprocess Systems Engineering
  152. Big Data Generation for Time Dependent Processes: The Tennessee Eastman Process for Generating Large Quantities of Process Data
  153. Integration of Computational Chemistry and Artificial Intelligence for Multi-scale Modeling of Bioprocesses
  154. Surrogate Modelling Based Uncertainty and Sensitivity Analysis for the Downstream Process Design of a Xylitol Biorefinery
  155. A compartment model for risk-based monitoring of lactic acid bacteria cultivations
  156. Model-based analysis of biocatalytic processes and performance of microbioreactors with integrated optical sensors
  157. From second generation feed-stocks to innovative fermentation and downstream techniques for succinic acid production
  158. Output uncertainty of dynamic growth models: Effect of uncertain parameter estimates on model reliability
  159. Quantitative Flow Cytometry to Understand Population Heterogeneity in Response to Changes in Substrate Availability in Escherichia coli and Saccharomyces cerevisiae Chemostats
  160. An exploration of barriers for commercializing phosphorus recovery technologies
  161. Meta-modeling based efficient global sensitivity analysis for wastewater treatment plants – An application to the BSM2 model
  162. Cleaning of toothpaste from vessel walls by impinging liquid jets and their falling films: quantitative modelling of soaking effects
  163. Benchmarking real-time monitoring strategies for ethanol production from lignocellulosic biomass
  164. Dynamic investigation and modeling of the nitrogen cometabolism in Methylococcus capsulatus ( Bath )
  165. An Industrial Perspective on Scale-Down Challenges Using Miniaturized Bioreactors
  166. Achieving value from process intensification through better process control
  167. Assessing the effects of intra-granule precipitation in a full-scale industrial anaerobic digester
  168. An integrated strategy for the effective production of bristle protein hydrolysate by the keratinolytic filamentous bacterium Amycolatopsis keratiniphila D2
  169. The effect of acetate on population heterogeneity in different cellular characteristics of Escherichia coli in aerobic batch cultures
  170. Evaluation of anaerobic digestion post-treatment options using an integrated model-based approach
  171. Plant-wide model-based analysis of iron dosage strategies for chemical phosphorus removal in wastewater treatment systems
  172. Model-Based Cost Optimization of Double-Effect Water-Lithium Bromide Absorption Refrigeration Systems
  173. A straightforward and easy way to derive a compartment model from a CFD model
  174. Sensors for biosensors: a novel tandem monitoring in a droplet towards efficient screening of robust design and optimal operating conditions
  175. BIOPRO-Sim: A benchmark simulation model for bio-manufacturing processes
  176. Facilitating learning by failure through a pedagogical model-based tool for bioprocesses
  177. Novel strategies for predictive particle monitoring and control using advanced image analysis
  178. Systematic decision-support methodology for identifying promising platform technologies towards circular economy
  179. Towards development of a decision support tool for conceptual design of wastewater treatment plants using stochastic simulation optimization
  180. CFD predicted pH gradients in lactic acid bacteria cultivations
  181. A Genome-Scale Metabolic Model for Methylococcus capsulatus (Bath) Suggests Reduced Efficiency Electron Transfer to the Particulate Methane Monooxygenase
  182. Investigation of the effect of uncertain growth kinetics on a CFD based model for the growth of S. cerevisiae in an industrial bioreactor
  183. Multi-function microfluidic platform for sensor integration
  184. A CFD based automatic method for compartment model development
  185. Economic Risk Analysis and Critical Comparison of Biodiesel Production Systems
  186. Screening of organic solvents for bioprocesses using aqueous-organic two-phase systems
  187. Resource recovery from bio-based production processes in developing Asia
  188. Resource recovery from organic solid waste using hydrothermal processing: Opportunities and challenges
  189. Investigation of the cleaning of egg yolk deposits from tank surfaces using continuous and pulsed flows
  190. Model-based analysis and optimization of a full-scale industrial high-rate anaerobic bioreactor
  191. Key control handles in integrated urban wastewater systems for improving receiving water quality
  192. A Systematic Methodology for Comprehensive Economic Assessment of Process Control Structures
  193. Occurrence, characterisation and fate of (nano)particulate Ti and Ag in two Norwegian wastewater treatment plants
  194. Anomaly Analysis in Cleaning-in-Place Operations of an Industrial Brewery Fermenter
  195. BIOPRO World Talent Campus: A week of real world challenge for biotechnology post-graduate students
  196. A probabilistic model-based soft sensor to monitor lactic acid bacteria fermentations
  197. Developing a framework to model the primary drying step of a continuous freeze-drying process based on infrared radiation
  198. A genome-scale metabolic model for Methylococcus capsulatus predicts reduced efficiency uphill electron transfer to pMMO.
  199. Dynamic Plantwide Modeling, Uncertainty, and Sensitivity Analysis of a Pharmaceutical Upstream Synthesis: Ibuprofen Case Study
  200. “Connecting worlds – a view on microfluidics for a wider application”
  201. Efficient Computational Design of a Scaffold for Cartilage Cell Regeneration
  202. Improved Prediction of Phosphorus Dynamics in Biotechnological Processes by Considering Precipitation and Polyphosphate Formation: A Case Study on Antibiotic Production with Streptomyces coelicolor
  203. Biocatalyst Screening with a Twist: Application of Oxygen Sensors Integrated in Microchannels for Screening Whole Cell Biocatalyst Variants
  204. Mechanistic modeling of cyclic voltammetry: A helpful tool for understanding biosensor principles and supporting design optimization
  205. Caught in-between: System for in-flow inactivation of enzymes as an intermediary step in “plug-and-play” microfluidic platforms
  206. Liquid-to-solid ratio control as an advanced process control solution for continuous twin-screw wet granulation
  207. Configuration optimization of series flow double-effect water-lithium bromide absorption refrigeration systems by cost minimization
  208. Global Sensitivity Analysis as Good Modelling Practices tool for the identification of the most influential process parameters of the primary drying step during freeze-drying
  209. Organic carbon recovery modeling for a rotating belt filter and its impact assessment on a plant-wide scale
  210. Experimental and computational evaluation of area selectively immobilized horseradish peroxidase in a microfluidic device
  211. Model-based process development for a continuous lactic acid bacteria fermentation
  212. A Methodology for Development of a Pedagogical Simulation Tool used in Fermentation Applications
  213. A shortcut approach for decision-making and operational analysis of an integrated end-to-end continuous pharmaceutical process
  214. Modeling for Process Risk Assessment in Industrial Bioprocesses
  215. Enzymatic keratin hydrolysis: Dynamic modelling, parameter estimation and validation
  216. Integrated Process Design and Control of Cyclic Distillation Columns
  217. Exploring the potential of electroless and electroplated noble metal–semiconductor hybrids within bio- and environmental sensing
  218. Implementation of a Radial Basis Function control strategy for the crystallization of Ibuprofen under uncertainty
  219. A fast and simple method to estimate relative, hyphal tensile-strength of filamentous fungi used to assess the effect of autophagy
  220. Quantitative risk assessment via uncertainty analysis in combination with error propagation for the determination of the dynamic Design Space of the primary drying step during freeze-drying
  221. Modelling an industrial anaerobic granular reactor using a multi-scale approach
  222. Evaluation of mixing and mass transfer in a stirred pilot scale bioreactor utilizing CFD
  223. Exploring the effects of ZVI addition on resource recovery in the anaerobic digestion process
  224. Resource recovery from bio-based production processes: a future necessity?
  225. Optimal Design and Planning of Glycerol-Based Biorefinery Supply Chains under Uncertainty
  226. A novel fuzzy-logic control strategy minimizing N 2 O emissions
  227. Mechanistic Fermentation Models for Process Design, Monitoring, and Control
  228. CFD modelling of axial mixing in the intermediate and final rinses of cleaning-in-place procedures of straight pipes
  229. Untargeted GC-MS Metabolomics Reveals Changes in the Metabolite Dynamics of Industrial Scale Batch Fermentations of Streptoccoccus thermophilus Broth
  230. Perspectives on Resource Recovery from Bio-Based Production Processes: From Concept to Implementation
  231. Application of iterative robust model-based optimal experimental design for the calibration of biocatalytic models
  232. A model library for simulation and benchmarking of integrated urban wastewater systems
  233. Understanding N 2 O formation mechanisms through sensitivity analyses using a plant-wide benchmark simulation model
  234. Supply Chain Optimization of Integrated Glycerol Biorefinery: GlyThink Model Development and Application
  235. Adding Value to Bioethanol through a Purification Process Revamp
  236. Plant-wide modelling of phosphorus transformations in wastewater treatment systems: Impacts of control and operational strategies
  237. CFD Modeling of Flow and Ion Exchange Kinetics in a Rotating Bed Reactor System
  238. A novel model-based control strategy for aerobic filamentous fungal fed-batch fermentation processes
  239. Shape optimization as a tool to design biocatalytic microreactors
  240. A review of control strategies for manipulating the feed rate in fed-batch fermentation processes
  241. Dynamic modelling of pectin extraction describing yield and functional characteristics
  242. Removal of benzaldehyde from a water/ethanol mixture by applying scavenging techniques
  243. A Consistent Methodology Based Parameter Estimation for a Lactic Acid Bacteria Fermentation Model
  244. An Efficient Experimental Design Strategy for Modelling and Characterization of Processes
  245. An Empirical Model for Carbon Recovery in a Rotating Belt Filter and Its Application in the Frame of Plantwide Evaluation
  246. Biorefinery Sustainability Analysis
  247. Reverse osmosis for water purification and reuse in the biotechnological industry: Process design, operation and economic guidelines
  248. Uncertainty & sensitivity analysis of economic assessment of lactic acid production from crude glycerol – impact of price correlations
  249. Uncertainty and Sensitivity Analysis for an Ibuprofen Synthesis Model Based on Hoechst Path
  250. ZVI Addition in Continuous Anaerobic Digestion Systems Dramatically Decreases P Recovery Potential: Dynamic Modelling
  251. Assessing the environmental sustainability of early stage design for bioprocesses under uncertainties: An analysis of glycerol bioconversion
  252. Modelling and sensitivity analysis of urinary platinum excretion in anticancer chemotherapy for the recovery of platinum
  253. A flexible well-mixed milliliter-scale reactor with high oxygen transfer rate for microbial cultivations
  254. Generation of synthetic influent data to perform (micro)pollutant wastewater treatment modelling studies
  255. NLP modeling for the optimization of LiBr-H2O absorption refrigeration systems with exergy loss rate, heat transfer area, and cost as single objective functions
  256. Development of in situ product removal strategies in biocatalysis applying scaled-down unit operations
  257. Development of a process map: A step towards a regime map for steady-state high shear wet twin screw granulation
  258. Systematic design of membership functions for fuzzy-logic control: A case study on one-stage partial nitritation/anammox treatment systems
  259. Application of a mechanistic model as a tool for on-line monitoring of pilot scale filamentous fungal fermentation processes-The importance of evaporation effects
  260. Mixing and mass transfer in a pilot scale U-loop bioreactor
  261. A generic model-based methodology for quantification of mass transfer limitations in microreactors
  262. Acceleration of Anti-Markovnikov Hydroamination in the Synthesis of an Active Pharmaceutical Ingredient
  263. Reaction invariant-based reduction of the activated sludge model ASM1 for batch applications
  264. Control structure design for resource recovery using the enhanced biological phosphorus removal and recovery (EBP2R) activated sludge process
  265. Linking granulation performance with residence time and granulation liquid distributions in twin-screw granulation: An experimental investigation
  266. Dynamic optimal foraging theory explains vertical migrations of Bigeye tuna
  267. Economic Risk Assessment of Early Stage Designs for Glycerol Valorization in Biorefinery Concepts
  268. Uncertainty analysis as essential step in the establishment of the dynamic Design Space of primary drying during freeze-drying
  269. A framework for techno-economic & environmental sustainability analysis by risk assessment for conceptual process evaluation
  270. Model-based analysis of a twin-screw wet granulation system for continuous solid dosage manufacturing
  271. Economic risk analysis and critical comparison of optimal biorefinery concepts
  272. Modelling phosphorus (P), sulfur (S) and iron (Fe) interactions for dynamic simulations of anaerobic digestion processes
  273. Catchment & sewer network simulation model to benchmark control strategies within urban wastewater systems
  274. A microfluidic toolbox for the development of in-situ product removal strategies in biocatalysis
  275. Implementation of Near-Infrared Spectroscopy for In-Line Monitoring of a Dehydration Reaction in a Tubular Laminar Reactor
  276. Functional unfold principal component regression methodology for analysis of industrial batch process data
  277. Optimal WWTP process selection for treatment of domestic wastewater – A realistic full-scale retrofitting study
  278. Fulgur: MATLAB GUI application for working with near infrared calibration sets. Part 2: the source code
  279. Modelling and simulation of a U-loop Reactor for Single Cell Protein Production
  280. Mechanistic Models for Process Development and Optimization of Fed-batch Fermentation Systems
  281. Quantifying the importance of flow maldistribution in numbered-up microreactors
  282. Geometry optimization of a fibrous scaffold based on mathematical modelling and CFD simulation of a dynamic cell culture
  283. Economic risk-based analysis: Effect of technical and market price uncertainties on the production of glycerol-based isobutanol
  284. Control of wastewater N2O emissions by balancing the microbial communities using a fuzzy-logic approach
  285. Early-Stage Design and Analysis of Biorefinery Networks
  286. Evaluation of an in-line particle imaging tool for monitoring twin-screw granulation performance
  287. ChemInform Abstract: Process Intensification Tools in the Small-Scale Pharmaceutical Manufacturing of Small Molecules
  288. A plant-wide aqueous phase chemistry module describing pH variations and ion speciation/pairing in wastewater treatment process models
  289. Aeration control by monitoring the microbiological activity using fuzzy logic diagnosis and control. Application to a complete autotrophic nitrogen removal reactor
  290. Process Intensification Tools in the Small-Scale Pharmaceutical Manufacturing of Small Molecules
  291. Microscale technology and biocatalytic processes: opportunities and challenges for synthesis
  292. Upgrading of lignocellulosic biorefinery to value-added chemicals: Sustainability and economics of bioethanol-derivatives
  293. RTD analysis in twin-screw granulation
  294. Effects of ionic strength and ion pairing on (plant-wide) modelling of anaerobic digestion
  295. Effects of influent fractionation, kinetics, stoichiometry and mass transfer on CH4, H2and CO2production for (plant-wide) modeling of anaerobic digesters
  296. Uncertainties in Early-Stage Capital Cost Estimation of Process Design – A Case Study on Biorefinery Design
  297. A mathematical programming framework for early stage design of wastewater treatment plants
  298. Assessment of Recent Process Analytical Technology (PAT) Trends: A Multiauthor Review
  299. Process Analytical Technologies in Biopharmaceutical Process Development
  300. A novel control strategy for single-stage autotrophic nitrogen removal in SBR
  301. Extending the benchmark simulation model n°2 with processes for nitrous oxide production and side-stream nitrogen removal
  302. A Framework for Sustainable Design of Algal Biorefineries: Economic Aspects and Life Cycle Analysis
  303. Fulgur: MATLAB GUI application for working with near infrared calibration sets. Part 1: The Fulgur application
  304. A Perspective on PSE in Fermentation Process Development and Operation
  305. Preface
  306. Fungal Morphology in Industrial Enzyme Production—Modelling and Monitoring
  307. Model-based characterisation of twin-screw granulation system for continuous solid dosage manufacturing
  308. A Numerical Procedure for Model Identifiability Analysis Applied to Enzyme Kinetics
  309. Control Structure Design of an Innovative Enhanced Biological Nutrient Recovery Activated Sludge System Coupled with a Photobioreactor
  310. Model-based optimization of the primary drying step during freeze-drying
  311. Model-Based Analysis and Efficient Operation of a Glucose Isomerization Reactor Plant
  312. Topology optimization for biocatalytic microreactor configurations
  313. State Estimation in Fermentation of Lignocellulosic Ethanol. Focus on the Use of pH Measurements
  314. Multivariate Analysis of Industrial Scale Fermentation Data
  315. Optimal Design of Algae Biorefinery Processing Networks for the production of Protein, Ethanol and Biodiesel
  316. Optimization-based methodology for wastewater treatment plant synthesis – a full scale retrofitting case study
  317. Population balance models: a useful complementary modelling framework for future WWTP modelling
  318. Modelling the occurrence, transport and fate of pharmaceuticals in wastewater systems
  319. Experimental investigation of granule size and shape dynamics in twin-screw granulation
  320. Experimental andin silicoinvestigation of population heterogeneity in continuousSachharomyces cerevisiaescale-down fermentation in a two-compartment setup
  321. Pressure Control in Distillation Columns: A Model-Based Analysis
  322. Filamentous Fungi Fermentation
  323. Challenges encountered when expanding activated sludge models: a case study based on N2O production
  324. Moisture and drug solid-state monitoring during a continuous drying process using empirical and mass balance models
  325. Benchmarking of Control Strategies for Wastewater Treatment Plants
  326. Crystallization Kinetics within a Generic Modeling Framework
  327. A systematic methodology for design of tailor-made blended products
  328. Development of novel control strategies for single-stage autotrophic nitrogen removal: A process oriented approach
  329. Mixing and transport during pharmaceutical twin-screw wet granulation: Experimental analysis via chemical imaging
  330. Comparison of techniques for reconstruction of a distribution from moments in the context of a pharmaceutical drying process
  331. Challenges in industrial fermentation technology research
  332. Effect of Market Price Uncertainties on the Design of Optimal Biorefinery Systems—A Systematic Approach
  333. Influence of selecting secondary settling tank sub-models on the calibration of WWTP models – A global sensitivity analysis using BSM2
  334. Analysing drying unit performance in a continuous pharmaceutical manufacturing line by means of mass – Energy balances
  335. The electrical breakdown of thin dielectric elastomers: thermal effects
  336. Calibration and validation of a phenomenological influent pollutant disturbance scenario generator using full-scale data
  337. Global sensitivity analysis applied to drying models for one or a population of granules
  338. Instrumentation, control and automation in wastewater – from London 1973 to Narbonne 2013
  339. Toward a Computer-Aided Synthesis and Design of Biorefinery Networks: Data Collection and Management Using a Generic Modeling Approach
  340. Balancing effluent quality, economic cost and greenhouse gas emissions during the evaluation of (plant-wide) control/operational strategies in WWTPs
  341. Biocatalytic process development using microfluidic miniaturized systems
  342. Superstructure Development and Optimization under Uncertainty for Design and Retrofit of Municipal Wastewater Treatment Plants
  343. reSystematic Development of Miniaturized (Bio)Processes using Process Systems Engineering (PSE) Methods and Tools
  344. The Virtual Product-Process Design Laboratory for Structured Chemical Product Design and Analysis
  345. Uncertainty Analysis in Raw Material and Utility Cost of Biorefinery Synthesis and Design
  346. Systematic substrate adoption methodology (SAM) for future flexible, generic pharmaceutical production processes
  347. Introducing uncertainty analysis of nucleation and crystal growth models in Process Analytical Technology (PAT) system design of crystallization processes
  348. Model-based analysis of high shear wet granulation from batch to continuous processes in pharmaceutical production – A critical review
  349. A GLUE uncertainty analysis of a drying model of pharmaceutical granules
  350. Advances in the Process Development of Biocatalytic Processes
  351. Process Systems Engineering, 5. Process Dynamics, Control, Monitoring, and Identification
  352. Process Systems Engineering, 1. Introduction
  353. A systematic framework for design of process monitoring and control (PAT) systems for crystallization processes
  354. Benchmark simulation models, quo vadis?
  355. pH variation and influence in an autotrophic nitrogen removing biofilm system using an efficient numerical solution strategy
  356. Microreactors and CFD as Tools for Biocatalysis Reactor Design: A case study
  357. Effect of nitrite, limited reactive settler and plant design configuration on the predicted performance of simultaneous C/N/P removal WWTPs
  358. 3D modelling of coupled mass and heat transfer of a convection-oven roasting process
  359. Calibration and validation of a model describing complete autotrophic nitrogen removal in a granular SBR system
  360. Development of a Population Balance Model of a pharmaceutical drying process and testing of solution methods
  361. Wastewater Treatment Models
  362. Synthesis and design of optimal biorefinery using an expanded network with thermochemical and biochemical biomass conversion platforms
  363. Design of Sustainable Blended Products using an Integrated Methodology
  364. Control of a Biological Nitrogen Removal Process in an Intensified Single Reactor Configuration
  365. A fuzzy-logic based diagnosis and control of a reactor performing complete autotrophic nitrogen removal
  366. Cell mass and cell cycle dynamics of an asynchronous budding yeast population: Experimental observations, flow cytometry data analysis, and multi-scale modeling
  367. Sensitivity analysis of autotrophic N removal by a granule based bioreactor: Influence of mass transfer versus microbial kinetics
  368. Process Systems Engineering, 9. Domain Engineering
  369. Active pharmaceutical ingredient (API) production involving continuous processes – A process system engineering (PSE)-assisted design framework
  370. Lab on a chip automates in vitro cell culturing
  371. Reduction of a single granule drying model: An essential step in preparation of a population balance model with a continuous growth term
  372. Monitoring and control of microbioreactors: An expert opinion on development needs
  373. Overview on Design Considerations for Development of Disposable Microbioreactor Prototypes
  374. Dynamics in population heterogeneity during batch and continuous fermentation of Saccharomyces cerevisiae
  375. Ask the Experts: The challenges and benefits of flow chemistry to optimize drug development
  376. Development of continuous pharmaceutical production processes supported by process systems engineering methods and tools
  377. A framework for model-based optimization of bioprocesses under uncertainty: Lignocellulosic ethanol production case
  378. A perspective on PSE in pharmaceutical process development and innovation
  379. Global sensitivity analysis of the BSM2 dynamic influent disturbance scenario generator
  380. Continuous Hydrolysis and Liquid–Liquid Phase Separation of an Active Pharmaceutical Ingredient Intermediate Using a Miniscale Hydrophobic Membrane Separator
  381. Monitoring and Control of a Continuous Grignard Reaction for the Synthesis of an Active Pharmaceutical Ingredient Intermediate Using Inline NIR spectroscopy
  382. Comparison of laser diffraction and image analysis for measurement of Streptomyces coelicolor cell clumps and pellets
  383. Soft sensors in bioprocessing: A status report and recommendations
  384. Benchmarking biological nutrient removal in wastewater treatment plants: influence of mathematical model assumptions
  385. Mechanistic modelling of the drying behaviour of single pharmaceutical granules
  386. Uncertainty and sensitivity analysis: Mathematical model of coupled heat and mass transfer for a contact baking process
  387. Applying Mechanistic Models in Bioprocess Development
  388. PSE opportunities in biocatalytic process design and development
  389. Computer-Aided Approach for Design of Tailor-Made Blended Products
  390. An Integrated Methodology for Design of Tailor-Made Blended Products
  391. Physiological heterogeneities in microbial populations and implications for physical stress tolerance
  392. Multi-scale modeling for prediction of distributed cellular properties in response to substrate spatial gradients in a continuously run microreactor
  393. Systematic identification of crystallization kinetics within a generic modelling framework
  394. Computational Fluid Dynamics at work - Design and Optimization of Microfluidic Applications
  395. A generic process template for continuous pharmaceutical production
  396. Evaluation of the energy efficiency of enzyme fermentation by mechanistic modeling
  397. Dynamic influent pollutant disturbance scenario generation using a phenomenological modelling approach
  398. Experimental methods and modeling techniques for description of cell population heterogeneity
  399. A Miniature Membrane Reactor for Evaluation of Process Design Options on the Enzymatic Degradation of Pectin
  400. Modelling of coupled heat and mass transfer during a contact baking process
  401. Mechanistic modelling of fluidized bed drying processes of wet porous granules: A review
  402. A generic multi-dimensional model-based system for batch cooling crystallization processes
  403. Wastewater Systems
  404. Introducing process analytical technology (PAT) in filamentous cultivation process development: comparison of advanced online sensors for biomass measurement
  405. Design of tailor-made chemical blend using a decomposition-based computer-aided approach
  406. Systematic procedure for generating operational policies to achieve target crystal size distribution (CSD) in batch cooling crystallization
  407. A Mathematical Model for Simultaneous Saccharification and Co-fermentation (SSCF) of C6 and C5 Sugars
  408. Modeling enzyme production with Aspergillus oryzae in pilot scale vessels with different agitation, aeration, and agitator types
  409. Process analytical technology (PAT) for biopharmaceuticals
  410. A continuous membrane microbioreactor system for development of integrated pectin modification and separation processes
  411. Multienzyme-Catalyzed Processes: Next-Generation Biocatalysis
  412. Ecological Models
  413. Global sensitivity analysis in wastewater treatment plant model applications: Prioritizing sources of uncertainty
  414. A systematic methodology for the design of continuous active pharmaceutical ingredient production processes
  415. Methodological Approach for Modeling of Multienzyme in-pot Processes
  416. A framework for model-based optimization of bioprocesses under uncertainty
  417. PSE in Pharmaceutical Process Development
  418. Dynamic model-based evaluation of process configurations for integrated operation of hydrolysis and co-fermentation for bioethanol production from lignocellulose
  419. Integration of Generic Multi-dimensional Model and Operational Policies for Batch Cooling Crystallization
  420. A retrofit strategy to achieve “Fast, Flexible, Future (F3)” pharmaceutical production processes
  421. Topology optimized microbioreactors
  422. A model-based methodology for simultaneous design and control of a bioethanol production process
  423. A model-based systems approach to pharmaceutical product-process design and analysis
  424. Benchmark Simulation Model No 2: finalisation of plant layout and default control strategy
  425. Assessing reliability of cellulose hydrolysis models to support biofuel process design—Identifiability and uncertainty analysis
  426. An ontological knowledge-based system for the selection of process monitoring and analysis tools
  427. ICAS-PAT: A software for design, analysis and validation of PAT systems
  428. Application of mechanistic models to fermentation and biocatalysis for next-generation processes
  429. Development of a single-use microbioreactor for cultivation of microorganisms
  430. Embedded resistance wire as a heating element for temperature control in microbioreactors
  431. Report and recommendation of a workshop on education and training for measurement, monitoring, modelling and control (M3C) in biochemical engineering
  432. Sensor combination and chemometric variable selection for online monitoring of Streptomyces coelicolor fed-batch cultivations
  433. New framework for standardized notation in wastewater treatment modelling
  434. Online monitoring of fermentation processes in lignocelluloses-to-bioalcohol production
  435. A new extant respirometric assay to estimate intrinsic growth parameters applied to study plasmid metabolic burden
  436. New Framework for Standardized Notation in Wastewater Treatment Modelling
  437. Synthesis, Design and Analysis of Downstream Separation in Bio-refinery Processes through a Group-Contribution Approach
  438. Control of Process Operations and Monitoring of Product Qualities through Generic Model-based in Batch Cooling Crystallization
  439. Contributor contact details
  440. In situ near infrared spectroscopy for analyte-specific monitoring of glucose and ammonium instreptomyces coelicolorfermentations
  441. Evaluation of plant-wide WWTP control strategies including the effects of filamentous bulking sludge
  442. Including the effects of filamentous bulking sludge during the simulation of wastewater treatment plants using a risk assessment model
  443. Wastewater treatment modelling: dealing with uncertainties
  444. On-line estimation of biomass, glucose and ethanol in Saccharomyces cerevisiae cultivations using in-situ multi-wavelength fluorescence and software sensors
  445. Mechanistic models and advanced model analysis within a PAT framework
  446. Monitoring of glucose and ammonium concentration in Streptomyces coelicolor fermentations using in situ Nir
  447. Biorefining: Computer aided tools for sustainable design and analysis of bioethanol production
  448. Application of microbioreactors in fermentation process development: a review
  449. Good modeling practice for PAT applications: Propagation of input uncertainty and sensitivity analysis
  450. Are Mechanistic Cellulose-hydrolysis Models Reliable for Use in Biofuel Process Design?—Identifiability and Sensitivity Analysis
  451. Uncertainty analysis in WWTP model applications: A critical discussion using an example from design
  452. Introducing mechanistic models in Process Analytical Technology education
  453. Uncertainty and sensitivity analysis of control strategies using the benchmark simulation model No1 (BSM1)
  454. Model-based computer-aided framework for design of process monitoring and analysis systems
  455. Application of near-infrared spectroscopy for monitoring and control of cell culture and fermentation
  456. Application of modeling and simulation tools for the evaluation of biocatalytic processes: A future perspective
  457. A software tool for design of process monitoring and analysis systems
  458. Improving the Morris method for sensitivity analysis by scaling the elementary effects
  459. Sensitivity Analysis of Non-Linear Dynamic Models: Prioritizing Experimental Research
  460. A Model-Based Methodology for Simultaneous Design and Control of a Bioethanol Production Process
  461. “Erratum to Editor's name” [Food and Bioproducts Processing (2008) 86 (2), outside back cover and contents list]
  462. Gassed and ungassed power draw in a pilot scale 550 litre fermentor retrofitted with up-pumping hydrofoil B2 impellers in media of different viscosity and with very high power draw
  463. Mixing by rotary jet heads: Indications of the benefits of head rotation under turbulent and transitional flow conditions
  464. Multi-criteria evaluation of wastewater treatment plant control strategies under uncertainty
  465. Risk assessment modelling of microbiology-related solids separation problems in activated sludge systems
  466. Modelling nitrite in wastewater treatment systems: a discussion of different modelling concepts
  467. Matrix notation for efficient development offirst-principlesmodels within PAT applications: Integrated modeling of antibiotic production withStreptomyces coelicolor
  468. Special issue – ECCE-6
  469. Wastewater Treatment Models
  470. Multivariate models for prediction of rheological characteristics of filamentous fermentation broth from the size distribution
  471. Classification and Diagnostic Output Prediction of Cancer Using Gene Expression Profiling and Supervised Machine Learning Algorithms
  472. Off-line design of PAT systems for on-line applications
  473. CAPE methods and tools for systematic analysis of new chemical product design and development
  474. Benchmark simulation model no 2: general protocol and exploratory case studies
  475. Application of multivariable statistical techniques in plant-wide WWTP control strategies analysis
  476. On-line monitoring of fermentation processes using multi-wavelength fluorescence
  477. Artificial neural networks for rapid WWTP performance evaluation: Methodology and case study
  478. ON-LINE ESTIMATION AND DETECTION OF ABNORMAL SUBSTRATE CONCENTRATIONS IN WWTPS USING A SOFTWARE SENSOR: A BENCHMARK STUDY
  479. Benchmark Simulation Model No 2 in Matlab-Simulink: towards plant-wide WWTP control strategy evaluation
  480. Integrated modelling of two xenobiotic organic compounds
  481. Plant-wide (BSM2) evaluation of reject water treatment with a SHARON-Anammox process
  482. Implementing ADM1 for plant-wide benchmark simulations in Matlab/Simulink
  483. Model Reduction Using Neural Networks Applied To The Modeling Of Integrated Urban Wastewater Systems
  484. Extension of the IWA/COST simulation benchmark to include expert reasoning for system performance evaluation
  485. Modelling and control strategy testing of biological and chemical phosphorus removal at Avedøre WWTP
  486. WWTP dynamic disturbance modelling–an essential module for long-term benchmarking development
  487. Demonstration of a tool for automatic learning and re-use of knowledge in the activated sludge process
  488. Efficient modelling necessitates standards for model documentation and exchange
  489. Impact of reactive settler models on simulated WWTP performance
  490. Towards a benchmark simulation model for plant-wide control strategy performance evaluation of WWTPs
  491. MODELLING FOR CONTROL: UNDERSTANDING ROLE AND FUNCTION OF REGULATORY NETWORKS IN MICROORGANISMS
  492. Activated sludge wastewater treatment plant modelling and simulation: state of the art
  493. Benchmarking combined biological phosphorus and nitrogen removal wastewater treatment processes
  494. Transient response of aerobic and anoxic activated sludge activities to sudden substrate concentration changes
  495. A simplified method to assess structurally identifiable parameters in Monod-based activated sludge models
  496. Calibration of Activated Sludge Models: A Critical Review of Experimental Designs
  497. A COMPREHENSIVE MODEL CALIBRATION PROCEDURE FOR ACTIVATED SLUDGE MODELS
  498. Modeling aerobic carbon source degradation processes using titrimetric data and combined respirometric-titrimetric data: Experimental data and model structure
  499. Modeling aerobic carbon source degradation processes using titrimetric data and combined respirometric-titrimetric data: Structural and practical identifiability
  500. Computer aided model analysis and dynamic simulation of a wastewater treatment plant
  501. CONTROL STRATEGY EVALUATION FOR COMBINED N AND P REMOVAL USING A BENCHMARK WASTEWATER TREATMENT PLANT
  502. Activated sludge monitoring with combined respirometric–titrimetric measurements
  503. A COMPREHENSIVE MODEL CALIBRATION PROCEDURE FOR ASM1
  504. A new pH-based procedure to model toxic effects on nitrifiers in activated sludge
  505. Measurement of ammonium concentration and nitrification rate by a new titrimetric biosensor
  506. Sensors to monitor biological nitrogen removal and activated sludge settling
  507. A titration technique for on-line nitrification monitoring in activated sludge
  508. ON-LINE ESTIMATION OF NITROSOMONAS KINETIC PARAMETERS IN ACTIVATED SLUDGE SAMPLES USING TITRATION IN-SENSOR-EXPERIMENTS
  509. Fast and sensitive acute toxicity detection with an enrichment nitrifying culture
  510. New Sensor Based on pH Effect of Denitrification Process
  511. On-Line Nitrification Monitoring in Activated Sludge with a Titrimetric Sensor
  512. Nitrification monitoring in activated sludge by oxygen uptake rate (OUR) measurements
  513. Biosensors for nitrogen control in wastewaters
  514. Nitrification Process Control in Activated Sludge Using Oxygen Uptake Rate Measurements
  515. Organic and ammonium nitrogen and oxygen in relation to granular sludge growth in lab-scale UASB reactors
  516. Towards Understanding the Role and Function of Regulatory Networks in Microorganisms