All Stories

  1. Flow-informed clustering of bioreactor volumes to build CFD-based compartment models
  2. A fluxomic model of microalgae photoautotrophic growth for application in industrial photobioreactors
  3. Gas–liquid mass-transfer modeling in industrial-scale bioreactors: A standardized framework and critical assessment
  4. High-Performance C++ and Julia solvers in CADET for weakly and strongly coupled continuous chromatography problems
  5. Liquid biofuels from waste: Modelling thermodynamic limits of the anaerobic biorefinery
  6. The Potential of Fermentation-Based Processing on Protein Modification: A Review
  7. A systematic screening of neural network‐based hybrid models of adsorption in chromatography processes
  8. Transfer learning for quantitative image analysis of biosolids
  9. Beyond ChatGMP: Improving LLM generation through user preferences
  10. Closing the loop: customized coding courses and chatbots embedded in a virtual lab to teach bioprocesses
  11. Diagnosing Faults in Wastewater Systems: A Data-Driven Approach to Handle Imbalanced Big Data
  12. Digital Shadow of a Pilot Scale Packed Batch Distillation Column for Real-Time Operator Training- and Support
  13. A teaching application of large language models
  14. Quantifying, predicting, and mitigating nitrous oxide emissions in a full-scale partial nitritation/anammox reactor treating reject water
  15. Dynamically predicting nitrous oxide emissions in a full-scale industrial activated sludge reactor under multiple aeration patterns and COD/N ratios
  16. Advancing regulatory dialogue: In silico models for improved vaccine biomanufacturing - an expert meeting report
  17. Holistic assessment of management strategies and technological solutions handling anaerobic digester supernatants in wastewater treatment plants
  18. CFD-guided scaling of Pseudomonas putida fermentation
  19. CADET-Julia: Efficient and versatile, open-source simulator for batch chromatography in Julia
  20. Trends der Entwicklung von digitalen Zwillingen für die Bioproduktionsindustrie
  21. Navigating industry 4.0 and 5.0: the role of hybrid modelling in (bio)chemical engineering’s digital transition
  22. Towards Education 4.0: The role of Large Language Models as virtual tutors in chemical engineering
  23. Isobutyric and n-butyric acid production from H2 and CO2 by Clostridium luticellarii in a hollow fiber membrane biofilm reactor: Reactor operation and process modelling
  24. Production of phosphate biofertilizers as a booster for the techno-economic and environmental performance of a first-generation sugarcane ethanol and sugar biorefinery
  25. Hybrid Modeling for On-Line Fermentation Optimization and Scale-Up: A Review
  26. Making waves: Power-to-X for the Water Resource Recovery Facilities of the future
  27. Data fusion of Raman spectra in MSPC for fault detection and diagnosis in pharmaceutical manufacturing
  28. Modernizing non-classical protein crystallization through industry 4.0: Advanced monitoring and modelling utilizing process analytical technology
  29. Raman spectroscopy and one‐dimensional convolutional neural network modeling as a real‐time monitoring tool for in vitro transaminase‐catalyzed synthesis of a pharmaceutically relevant amine precursor
  30. Accelerating vaccine manufacturing development through model-based approaches: current advances and future opportunities
  31. Preface of the 2nd International Electronic Conference on Processes (ECP 2023)
  32. Nitrous oxide emissions from two full-scale membrane-aerated biofilm reactors
  33. Water innovation in industrial symbiosis - A global review
  34. A process systems engineering view of environmental impact assessment in renewable and sustainable energy production: Status and perspectives
  35. A Process Monitoring Framework for Imbalanced Big Data: A Wastewater Treatment Plant Case Study
  36. Big Data Analytics for Advanced Fault Detection in Wastewater Treatment Plants
  37. Discontinuous Galerkin spectral element method for continuous chromatography: Application to the Lumped Rate Model without pores
  38. FermentAI: Large Language Models in Chemical Engineering Education for Learning Fermentation Processes
  39. Overcoming the challenges of dynamic systems in steady-state simulations: the use of meta-modeling as a surrogate for complex kinetic models
  40. Towards Modelling of an Industrial Aspergillus oryzae Aerobic Fed-batch Fermentation Process – Process Characterization Across Scales
  41. Shortcut design method for multicomponent gradient simulated moving beds
  42. Statement of Peer Review
  43. SPyCE: A structured and tailored series of Python courses for (bio)chemical engineers
  44. A data analytics pipeline to optimize polymer dose strategy in a semi-continuous multi-feed dewatering system
  45. Modelling of industrial-scale bioreactors using the particle lifeline approach
  46. Life cycle assessment of an integrated xylitol biorefinery with value-added co-products
  47. Digital tools in chemical engineering education: The needs and the desires
  48. Modelling and Economic Optimal Control for a Laboratory-scale Continuous Stirred Tank Reactor for Single-cell Protein Production
  49. Designing a fault detection classifier framework for an industrial dynamic ultrafiltration membrane process using wavelet-based feature analysis
  50. Transforming data into actionable knowledge for fault detection, diagnosis and prognosis in urban wastewater systems with AI techniques: A mini-review
  51. Integrated capacity and production planning in the pharmaceutical supply chain: Framework and models
  52. Modelling the impacts of operational conditions on the performance of a full-scale membrane aerated biofilm reactor
  53. The effects of low oxidation-reduction potential on the performance of full-scale hybrid membrane-aerated biofilm reactors
  54. Design of multi-component gradient SMBs
  55. Digital Twins in Pilot Scale Fermentation: Non-Linear State Estimation for Improving Induction Timing
  56. Handheld FTIR outperforms total organic carbon swab in pharmaceutical cleaning validation
  57. Integrating Python in the (bio)chemical engineering curriculum: challenges and opportunities
  58. NyctiDB: A non-relational bioprocesses modeling database supported by an ontology
  59. Digital models in biotechnology: Towards multi-scale integration and implementation
  60. From Paper to web: Students as partners for virtual laboratories in (Bio)chemical engineering education
  61. Prediction of mass and volumetric flows in a full-scale industrial waste treatment plant
  62. Data-based dynamic compartment model: Modeling ofE. colifed-batch fermentation in a 600 m3 bubble column
  63. Economic, technical, and environmental evaluation of retrofitting scenarios in a full-scale industrial wastewater treatment system
  64. To be fAIr: ethical and fair application of artificial intelligence in virtual laboratories
  65. Corrigendum to ‘Economic and environmental analysis of bio-succinic acid production: From established processes to a new continuous fermentation approach with in-situ electrolytic extraction’ [Chemical Engineering Research and Design Volume 179, March ...
  66. Rendered-Protein Hydrolysates as a Low-Cost Nitrogen Source for the Fungal Biotransformation of 5-Hydroxymethylfurfural
  67. Shaping an Open Microbiome for Butanol Production through Process Control
  68. Optimal Conversion of Organic Wastes to Value-Added Products: Toward a Sustainable Integrated Biorefinery in Denmark
  69. Sampling Error of TOC swab in Pharmaceutical Cleaning Verification
  70. Mathematical Modeling of the Electro-Oxidation Process
  71. Plant-wide assessment of alternative activated sludge configurations for biological nutrient removal under uncertain influent characteristics
  72. Benchmarking strategies to control GHG production and emissions
  73. Digitalisation in chemical engineering: Industrial needs, academic best practice, and curriculum limitations
  74. Economic and environmental analysis of bio-succinic acid production: From established processes to a new continuous fermentation approach with in-situ electrolytic extraction
  75. Conceptual Process Design of an Integrated Xylitol Biorefinery With Value-Added Co-Products
  76. Model development for the optimization of operational conditions of the pretreatment of wheat straw
  77. Soft‐sensors application for automated feeding control in high‐throughput mammalian cell cultures
  78. Plant wide modelling of a full-scale industrial water treatment system
  79. A combinatorial tool for monitoring flocculation processes: Using non-invasive measurements and hybrid deep learning assisted modelling
  80. Computational fluid dynamics modelling of hydrodynamics, mixing and oxygen transfer in industrial bioreactors with Newtonian broths
  81. Digital Twin of a pilot-scale bio-production setup
  82. Dynamic Modeling and Control of a Continuous Biopharmaceutical Manufacturing Plant
  83. Educational Computer-Aided Tools Towards Industry 4.0: Recommendations and BioVL
  84. Forecasting Operational Conditions: A case-study from dewatering of biomass at an industrial wastewater treatment plant
  85. Holistic Capacity Management and Production Planning in the Pharmaceutical Supply Chain
  86. LCA modelling as a decision-tool for experimental design: the case of extraction of astaxanthin from crab waste
  87. Modeling and Simulation of Upstream and Downstream Processes for Monoclonal Antibody Production
  88. On-line monitoring of process parameters during fermentation
  89. Pilot Plant 4.0: A Review of Digitalization Efforts of the Chemical and Biochemical Engineering Department at the Technical University of Denmark (DTU)
  90. Sensitivity Analysis and Risk Assessment for the In-Silico Design and Use of Optimized Cell Factories in a Xylitol Biorefinery
  91. Separation of succinic acid from fermentation broth: Dielectric exclusion, Donnan effect and diffusion as the most influential mass transfer mechanisms
  92. Value Chain Optimization of a Xylitol Biorefinery with Delaunay Triangulation Regression Models
  93. Co-cultivation of a novel Fusarium striatum strain and a xylose consuming Saccharomyces cerevisiae yields an efficient process for simultaneous detoxification and fermentation of lignocellulosic hydrolysates
  94. Fault diagnosis of chemical processes based on joint recurrence quantification analysis
  95. Integration of first-principle models and machine learning in a modeling framework: An application to flocculation
  96. Modelling and control of an integrated high purity methanol distillation configuration
  97. Exceptionally rich keratinolytic enzyme profile found in the rare actinomycetes Amycolatopsis keratiniphila D2T
  98. Characterization of mixing performance in bioreactors using flow-following sensor devices
  99. Techno-economic and environmental impact assessment of biogas production and fertiliser recovery from pelagic Sargassum: A biorefinery concept for Barbados
  100. Mechanisms, status, and challenges of thermal hydrolysis and advanced thermal hydrolysis processes in sewage sludge treatment
  101. Towards Digitalization in Bio-Manufacturing Operations: A Survey on Application of Big Data and Digital Twin Concepts in Denmark
  102. Automated Compartment Model Development Based on Data from Flow-Following Sensor Devices
  103. An easy to use GUI for simulating big data using Tennessee Eastman process
  104. Alone or together? A review on pure and mixed microbial cultures for butanol production
  105. Assessment of alkaline stabilization processes in industrial waste streams using a model-based approach
  106. Development of dynamic compartment models for industrial aerobic fed-batch fermentation processes
  107. Microbial biofilms in biorefinery – Towards a sustainable production of low-value bulk chemicals and fuels
  108. A framework for the development of Pedagogical Process Simulators (P2Si) using explanatory models and gamification
  109. Synergistic optimization framework for the process synthesis and design of biorefineries
  110. Long-term operation assessment of a full-scale membrane-aerated biofilm reactor under Nordic conditions
  111. Particle-Scale Modeling to Understand Liquid Distribution in Twin-Screw Wet Granulation
  112. Model-Based Evaluation of a Data-Driven Control Strategy: Application to Ibuprofen Crystallization
  113. Analysis of the response of the cell membrane of Saccharomyces cerevisiae during the detoxification of common lignocellulosic inhibitors
  114. Digital Twin in biomanufacturing: challenges and opportunities towards its implementation
  115. Simulation-based evaluation of sludge management strategies in a WWTP
  116. Special Issue on “Recent Advances in Population Balance Modeling”
  117. Incremental design of water symbiosis networks with prior knowledge: The case of an industrial park in Kenya
  118. Understanding gradients in industrial bioreactors
  119. An uncertainty-aware hybrid modelling approach using probabilistic machine learning
  120. Implementation of first-principles surface interactions in a hybrid machine learning assisted modelling of flocculation
  121. Modelling and Dynamic Optimization of beer fermentation towards optimal flavor and operation
  122. Programming skills across the (bio)engineering curriculum – a students’ perspective
  123. Sustainable bio-succinic acid production: superstructure optimization, techno-economic, and lifecycle assessment
  124. Towards a Digital Twin: A validated Digital Model of a Pilot Scale Bioreactor producing Green Fluorescent Protein (GFP)
  125. Unsupervised Monitoring of Flocculation Processes based on Recurrence Theory
  126. Why Is Batch Processing Still Dominating the Biologics Landscape? Towards an Integrated Continuous Bioprocessing Alternative
  127. Electrochemical tuning of alcohol oxidase and dehydrogenase catalysis via biosensing towards butanol-1 detection in fermentation media
  128. Stochastic simulation-based superstructure optimization framework for process synthesis and design under uncertainty
  129. Promoting the co-utilisation of glucose and xylose in lignocellulosic ethanol fermentations using a data-driven feed-back controller
  130. Transforming data to information: A parallel hybrid model for real‐time state estimation in lignocellulosic ethanol fermentation
  131. Separation of middle boiling trace compounds by distillation: An investigation of practical implications of complex column arrangements on an industrial methanol distillation case study
  132. Towards smart biomanufacturing: a perspective on recent developments in industrial measurement and monitoring technologies for bio-based production processes
  133. Hybrid machine learning assisted modelling framework for particle processes
  134. The Role of Big Data in Industrial (Bio)chemical Process Operations
  135. Automated Electrochemical Glucose Biosensor Platform as an Efficient Tool Toward On-Line Fermentation Monitoring: Novel Application Approaches and Insights
  136. Towards a digital twin: a hybrid data‐driven and mechanistic digital shadow to forecast the evolution of lignocellulosic fermentation
  137. Dynamic model validation and advanced polymer control for rotating belt filtration as primary treatment of domestic wastewaters
  138. Assessment of the fate of organic micropollutants in novel wastewater treatment plant configurations through an empirical mechanistic model
  139. Design and Application of an Electrochemical Sensor for Ammonium Monitoring in Bioprocesses
  140. Monitoring yeast fermentations by nonlinear infrared technology and chemometrics—understanding process correlations and indirect predictions
  141. A process synthesis tool for WWTP – An application to design sustainable energy recovery facilities
  142. Distinguishing Commercial Beers Using a Solution-Based Sensor Array Derived from Nanoscale Polydiacetylene Vesicles
  143. Application of Organic-Inorganic Hybrids in Chemical Analysis, Bio- and Environmental Monitoring
  144. Modeling and system identification of an unconventional bioreactor used for single cell protein production
  145. Two novel S1 peptidases from Amycolatopsis keratinophila subsp. keratinophila D2T degrading keratinous slaughterhouse by-products
  146. A novel use for an old problem: The Tennessee Eastman challenge process as an activating teaching tool
  147. Resource recovery from waste streams in a water-energy-food nexus perspective: Toward more sustainable food processing
  148. Towards one-step design of tailored enzymatic nanobiosensors
  149. Model-Based Tools for Pharmaceutical Manufacturing Processes
  150. Flow-following sensors for fermentation processes - an overview
  151. Towards the Development of Digital Twins for the Bio-manufacturing Industry
  152. A Hybrid Model Predictive Control Strategy using Neural Network Based Soft Sensors for Particle Processes
  153. An E-learning Bot for Bioprocess Systems Engineering
  154. Big Data Generation for Time Dependent Processes: The Tennessee Eastman Process for Generating Large Quantities of Process Data
  155. Integration of Computational Chemistry and Artificial Intelligence for Multi-scale Modeling of Bioprocesses
  156. Surrogate Modelling Based Uncertainty and Sensitivity Analysis for the Downstream Process Design of a Xylitol Biorefinery
  157. A compartment model for risk-based monitoring of lactic acid bacteria cultivations
  158. Model-based analysis of biocatalytic processes and performance of microbioreactors with integrated optical sensors
  159. From second generation feed-stocks to innovative fermentation and downstream techniques for succinic acid production
  160. Output uncertainty of dynamic growth models: Effect of uncertain parameter estimates on model reliability
  161. Quantitative Flow Cytometry to Understand Population Heterogeneity in Response to Changes in Substrate Availability in Escherichia coli and Saccharomyces cerevisiae Chemostats
  162. An exploration of barriers for commercializing phosphorus recovery technologies
  163. Meta-modeling based efficient global sensitivity analysis for wastewater treatment plants – An application to the BSM2 model
  164. Cleaning of toothpaste from vessel walls by impinging liquid jets and their falling films: quantitative modelling of soaking effects
  165. Benchmarking real-time monitoring strategies for ethanol production from lignocellulosic biomass
  166. Dynamic investigation and modeling of the nitrogen cometabolism in Methylococcus capsulatus ( Bath )
  167. An Industrial Perspective on Scale-Down Challenges Using Miniaturized Bioreactors
  168. Achieving value from process intensification through better process control
  169. Assessing the effects of intra-granule precipitation in a full-scale industrial anaerobic digester
  170. An integrated strategy for the effective production of bristle protein hydrolysate by the keratinolytic filamentous bacterium Amycolatopsis keratiniphila D2
  171. The effect of acetate on population heterogeneity in different cellular characteristics of Escherichia coli in aerobic batch cultures
  172. Evaluation of anaerobic digestion post-treatment options using an integrated model-based approach
  173. Plant-wide model-based analysis of iron dosage strategies for chemical phosphorus removal in wastewater treatment systems
  174. Model-Based Cost Optimization of Double-Effect Water-Lithium Bromide Absorption Refrigeration Systems
  175. A straightforward and easy way to derive a compartment model from a CFD model
  176. Sensors for biosensors: a novel tandem monitoring in a droplet towards efficient screening of robust design and optimal operating conditions
  177. BIOPRO-Sim: A benchmark simulation model for bio-manufacturing processes
  178. Facilitating learning by failure through a pedagogical model-based tool for bioprocesses
  179. Novel strategies for predictive particle monitoring and control using advanced image analysis
  180. Systematic decision-support methodology for identifying promising platform technologies towards circular economy
  181. Towards development of a decision support tool for conceptual design of wastewater treatment plants using stochastic simulation optimization
  182. CFD predicted pH gradients in lactic acid bacteria cultivations
  183. A Genome-Scale Metabolic Model for Methylococcus capsulatus (Bath) Suggests Reduced Efficiency Electron Transfer to the Particulate Methane Monooxygenase
  184. Investigation of the effect of uncertain growth kinetics on a CFD based model for the growth of S. cerevisiae in an industrial bioreactor
  185. Multi-function microfluidic platform for sensor integration
  186. A CFD based automatic method for compartment model development
  187. Economic Risk Analysis and Critical Comparison of Biodiesel Production Systems
  188. Screening of organic solvents for bioprocesses using aqueous-organic two-phase systems
  189. Resource recovery from bio-based production processes in developing Asia
  190. Resource recovery from organic solid waste using hydrothermal processing: Opportunities and challenges
  191. Investigation of the cleaning of egg yolk deposits from tank surfaces using continuous and pulsed flows
  192. Model-based analysis and optimization of a full-scale industrial high-rate anaerobic bioreactor
  193. Key control handles in integrated urban wastewater systems for improving receiving water quality
  194. A Systematic Methodology for Comprehensive Economic Assessment of Process Control Structures
  195. Occurrence, characterisation and fate of (nano)particulate Ti and Ag in two Norwegian wastewater treatment plants
  196. Anomaly Analysis in Cleaning-in-Place Operations of an Industrial Brewery Fermenter
  197. BIOPRO World Talent Campus: A week of real world challenge for biotechnology post-graduate students
  198. A probabilistic model-based soft sensor to monitor lactic acid bacteria fermentations
  199. Developing a framework to model the primary drying step of a continuous freeze-drying process based on infrared radiation
  200. A genome-scale metabolic model for Methylococcus capsulatus predicts reduced efficiency uphill electron transfer to pMMO.
  201. Dynamic Plantwide Modeling, Uncertainty, and Sensitivity Analysis of a Pharmaceutical Upstream Synthesis: Ibuprofen Case Study
  202. “Connecting worlds – a view on microfluidics for a wider application”
  203. Efficient Computational Design of a Scaffold for Cartilage Cell Regeneration
  204. Improved Prediction of Phosphorus Dynamics in Biotechnological Processes by Considering Precipitation and Polyphosphate Formation: A Case Study on Antibiotic Production with Streptomyces coelicolor
  205. Biocatalyst Screening with a Twist: Application of Oxygen Sensors Integrated in Microchannels for Screening Whole Cell Biocatalyst Variants
  206. Mechanistic modeling of cyclic voltammetry: A helpful tool for understanding biosensor principles and supporting design optimization
  207. Caught in-between: System for in-flow inactivation of enzymes as an intermediary step in “plug-and-play” microfluidic platforms
  208. Liquid-to-solid ratio control as an advanced process control solution for continuous twin-screw wet granulation
  209. Configuration optimization of series flow double-effect water-lithium bromide absorption refrigeration systems by cost minimization
  210. Global Sensitivity Analysis as Good Modelling Practices tool for the identification of the most influential process parameters of the primary drying step during freeze-drying
  211. Organic carbon recovery modeling for a rotating belt filter and its impact assessment on a plant-wide scale
  212. Experimental and computational evaluation of area selectively immobilized horseradish peroxidase in a microfluidic device
  213. Model-based process development for a continuous lactic acid bacteria fermentation
  214. A Methodology for Development of a Pedagogical Simulation Tool used in Fermentation Applications
  215. A shortcut approach for decision-making and operational analysis of an integrated end-to-end continuous pharmaceutical process
  216. Modeling for Process Risk Assessment in Industrial Bioprocesses
  217. Enzymatic keratin hydrolysis: Dynamic modelling, parameter estimation and validation
  218. Integrated Process Design and Control of Cyclic Distillation Columns
  219. Exploring the potential of electroless and electroplated noble metal–semiconductor hybrids within bio- and environmental sensing
  220. Implementation of a Radial Basis Function control strategy for the crystallization of Ibuprofen under uncertainty
  221. A fast and simple method to estimate relative, hyphal tensile-strength of filamentous fungi used to assess the effect of autophagy
  222. Quantitative risk assessment via uncertainty analysis in combination with error propagation for the determination of the dynamic Design Space of the primary drying step during freeze-drying
  223. Modelling an industrial anaerobic granular reactor using a multi-scale approach
  224. Evaluation of mixing and mass transfer in a stirred pilot scale bioreactor utilizing CFD
  225. Exploring the effects of ZVI addition on resource recovery in the anaerobic digestion process
  226. Resource recovery from bio-based production processes: a future necessity?
  227. Optimal Design and Planning of Glycerol-Based Biorefinery Supply Chains under Uncertainty
  228. A novel fuzzy-logic control strategy minimizing N 2 O emissions
  229. Mechanistic Fermentation Models for Process Design, Monitoring, and Control
  230. CFD modelling of axial mixing in the intermediate and final rinses of cleaning-in-place procedures of straight pipes
  231. Untargeted GC-MS Metabolomics Reveals Changes in the Metabolite Dynamics of Industrial Scale Batch Fermentations of Streptoccoccus thermophilus Broth
  232. Perspectives on Resource Recovery from Bio-Based Production Processes: From Concept to Implementation
  233. Application of iterative robust model-based optimal experimental design for the calibration of biocatalytic models
  234. A model library for simulation and benchmarking of integrated urban wastewater systems
  235. Understanding N 2 O formation mechanisms through sensitivity analyses using a plant-wide benchmark simulation model
  236. Supply Chain Optimization of Integrated Glycerol Biorefinery: GlyThink Model Development and Application
  237. Adding Value to Bioethanol through a Purification Process Revamp
  238. Plant-wide modelling of phosphorus transformations in wastewater treatment systems: Impacts of control and operational strategies
  239. CFD Modeling of Flow and Ion Exchange Kinetics in a Rotating Bed Reactor System
  240. A novel model-based control strategy for aerobic filamentous fungal fed-batch fermentation processes
  241. Shape optimization as a tool to design biocatalytic microreactors
  242. A review of control strategies for manipulating the feed rate in fed-batch fermentation processes
  243. Dynamic modelling of pectin extraction describing yield and functional characteristics
  244. Removal of benzaldehyde from a water/ethanol mixture by applying scavenging techniques
  245. A Consistent Methodology Based Parameter Estimation for a Lactic Acid Bacteria Fermentation Model
  246. An Efficient Experimental Design Strategy for Modelling and Characterization of Processes
  247. An Empirical Model for Carbon Recovery in a Rotating Belt Filter and Its Application in the Frame of Plantwide Evaluation
  248. Biorefinery Sustainability Analysis
  249. Reverse osmosis for water purification and reuse in the biotechnological industry: Process design, operation and economic guidelines
  250. Uncertainty & sensitivity analysis of economic assessment of lactic acid production from crude glycerol – impact of price correlations
  251. Uncertainty and Sensitivity Analysis for an Ibuprofen Synthesis Model Based on Hoechst Path
  252. ZVI Addition in Continuous Anaerobic Digestion Systems Dramatically Decreases P Recovery Potential: Dynamic Modelling
  253. Assessing the environmental sustainability of early stage design for bioprocesses under uncertainties: An analysis of glycerol bioconversion
  254. Modelling and sensitivity analysis of urinary platinum excretion in anticancer chemotherapy for the recovery of platinum
  255. A flexible well-mixed milliliter-scale reactor with high oxygen transfer rate for microbial cultivations
  256. Generation of synthetic influent data to perform (micro)pollutant wastewater treatment modelling studies
  257. NLP modeling for the optimization of LiBr-H2O absorption refrigeration systems with exergy loss rate, heat transfer area, and cost as single objective functions
  258. Development of in situ product removal strategies in biocatalysis applying scaled-down unit operations
  259. Development of a process map: A step towards a regime map for steady-state high shear wet twin screw granulation
  260. Systematic design of membership functions for fuzzy-logic control: A case study on one-stage partial nitritation/anammox treatment systems
  261. Application of a mechanistic model as a tool for on-line monitoring of pilot scale filamentous fungal fermentation processes-The importance of evaporation effects
  262. Mixing and mass transfer in a pilot scale U-loop bioreactor
  263. A generic model-based methodology for quantification of mass transfer limitations in microreactors
  264. Acceleration of Anti-Markovnikov Hydroamination in the Synthesis of an Active Pharmaceutical Ingredient
  265. Reaction invariant-based reduction of the activated sludge model ASM1 for batch applications
  266. Control structure design for resource recovery using the enhanced biological phosphorus removal and recovery (EBP2R) activated sludge process
  267. Linking granulation performance with residence time and granulation liquid distributions in twin-screw granulation: An experimental investigation
  268. Dynamic optimal foraging theory explains vertical migrations of Bigeye tuna
  269. Economic Risk Assessment of Early Stage Designs for Glycerol Valorization in Biorefinery Concepts
  270. Uncertainty analysis as essential step in the establishment of the dynamic Design Space of primary drying during freeze-drying
  271. A framework for techno-economic & environmental sustainability analysis by risk assessment for conceptual process evaluation
  272. Model-based analysis of a twin-screw wet granulation system for continuous solid dosage manufacturing
  273. Economic risk analysis and critical comparison of optimal biorefinery concepts
  274. Modelling phosphorus (P), sulfur (S) and iron (Fe) interactions for dynamic simulations of anaerobic digestion processes
  275. Catchment & sewer network simulation model to benchmark control strategies within urban wastewater systems
  276. A microfluidic toolbox for the development of in-situ product removal strategies in biocatalysis
  277. Implementation of Near-Infrared Spectroscopy for In-Line Monitoring of a Dehydration Reaction in a Tubular Laminar Reactor
  278. Functional unfold principal component regression methodology for analysis of industrial batch process data
  279. Optimal WWTP process selection for treatment of domestic wastewater – A realistic full-scale retrofitting study
  280. Fulgur: MATLAB GUI application for working with near infrared calibration sets. Part 2: the source code
  281. Modelling and simulation of a U-loop Reactor for Single Cell Protein Production
  282. Mechanistic Models for Process Development and Optimization of Fed-batch Fermentation Systems
  283. Quantifying the importance of flow maldistribution in numbered-up microreactors
  284. Geometry optimization of a fibrous scaffold based on mathematical modelling and CFD simulation of a dynamic cell culture
  285. Economic risk-based analysis: Effect of technical and market price uncertainties on the production of glycerol-based isobutanol
  286. Control of wastewater N2O emissions by balancing the microbial communities using a fuzzy-logic approach
  287. Early-Stage Design and Analysis of Biorefinery Networks
  288. Evaluation of an in-line particle imaging tool for monitoring twin-screw granulation performance
  289. ChemInform Abstract: Process Intensification Tools in the Small-Scale Pharmaceutical Manufacturing of Small Molecules
  290. A plant-wide aqueous phase chemistry module describing pH variations and ion speciation/pairing in wastewater treatment process models
  291. Aeration control by monitoring the microbiological activity using fuzzy logic diagnosis and control. Application to a complete autotrophic nitrogen removal reactor
  292. Process Intensification Tools in the Small-Scale Pharmaceutical Manufacturing of Small Molecules
  293. Microscale technology and biocatalytic processes: opportunities and challenges for synthesis
  294. Upgrading of lignocellulosic biorefinery to value-added chemicals: Sustainability and economics of bioethanol-derivatives
  295. RTD analysis in twin-screw granulation
  296. Effects of ionic strength and ion pairing on (plant-wide) modelling of anaerobic digestion
  297. Effects of influent fractionation, kinetics, stoichiometry and mass transfer on CH4, H2and CO2production for (plant-wide) modeling of anaerobic digesters
  298. Uncertainties in Early-Stage Capital Cost Estimation of Process Design – A Case Study on Biorefinery Design
  299. A mathematical programming framework for early stage design of wastewater treatment plants
  300. Assessment of Recent Process Analytical Technology (PAT) Trends: A Multiauthor Review
  301. Process Analytical Technologies in Biopharmaceutical Process Development
  302. A novel control strategy for single-stage autotrophic nitrogen removal in SBR
  303. Extending the benchmark simulation model n°2 with processes for nitrous oxide production and side-stream nitrogen removal
  304. A Framework for Sustainable Design of Algal Biorefineries: Economic Aspects and Life Cycle Analysis
  305. Fulgur: MATLAB GUI application for working with near infrared calibration sets. Part 1: The Fulgur application
  306. A Perspective on PSE in Fermentation Process Development and Operation
  307. Preface
  308. Fungal Morphology in Industrial Enzyme Production—Modelling and Monitoring
  309. Model-based characterisation of twin-screw granulation system for continuous solid dosage manufacturing
  310. A Numerical Procedure for Model Identifiability Analysis Applied to Enzyme Kinetics
  311. Control Structure Design of an Innovative Enhanced Biological Nutrient Recovery Activated Sludge System Coupled with a Photobioreactor
  312. Model-based optimization of the primary drying step during freeze-drying
  313. Model-Based Analysis and Efficient Operation of a Glucose Isomerization Reactor Plant
  314. Topology optimization for biocatalytic microreactor configurations
  315. State Estimation in Fermentation of Lignocellulosic Ethanol. Focus on the Use of pH Measurements
  316. Multivariate Analysis of Industrial Scale Fermentation Data
  317. Optimal Design of Algae Biorefinery Processing Networks for the production of Protein, Ethanol and Biodiesel
  318. Optimization-based methodology for wastewater treatment plant synthesis – a full scale retrofitting case study
  319. Population balance models: a useful complementary modelling framework for future WWTP modelling
  320. Modelling the occurrence, transport and fate of pharmaceuticals in wastewater systems
  321. Experimental investigation of granule size and shape dynamics in twin-screw granulation
  322. Experimental andin silicoinvestigation of population heterogeneity in continuousSachharomyces cerevisiaescale-down fermentation in a two-compartment setup
  323. Pressure Control in Distillation Columns: A Model-Based Analysis
  324. Filamentous Fungi Fermentation
  325. Challenges encountered when expanding activated sludge models: a case study based on N2O production
  326. Moisture and drug solid-state monitoring during a continuous drying process using empirical and mass balance models
  327. Benchmarking of Control Strategies for Wastewater Treatment Plants
  328. Crystallization Kinetics within a Generic Modeling Framework
  329. A systematic methodology for design of tailor-made blended products
  330. Development of novel control strategies for single-stage autotrophic nitrogen removal: A process oriented approach
  331. Mixing and transport during pharmaceutical twin-screw wet granulation: Experimental analysis via chemical imaging
  332. Comparison of techniques for reconstruction of a distribution from moments in the context of a pharmaceutical drying process
  333. Challenges in industrial fermentation technology research
  334. Effect of Market Price Uncertainties on the Design of Optimal Biorefinery Systems—A Systematic Approach
  335. Influence of selecting secondary settling tank sub-models on the calibration of WWTP models – A global sensitivity analysis using BSM2
  336. Analysing drying unit performance in a continuous pharmaceutical manufacturing line by means of mass – Energy balances
  337. The electrical breakdown of thin dielectric elastomers: thermal effects
  338. Calibration and validation of a phenomenological influent pollutant disturbance scenario generator using full-scale data
  339. Global sensitivity analysis applied to drying models for one or a population of granules
  340. Instrumentation, control and automation in wastewater – from London 1973 to Narbonne 2013
  341. Toward a Computer-Aided Synthesis and Design of Biorefinery Networks: Data Collection and Management Using a Generic Modeling Approach
  342. Balancing effluent quality, economic cost and greenhouse gas emissions during the evaluation of (plant-wide) control/operational strategies in WWTPs
  343. Biocatalytic process development using microfluidic miniaturized systems
  344. Superstructure Development and Optimization under Uncertainty for Design and Retrofit of Municipal Wastewater Treatment Plants
  345. reSystematic Development of Miniaturized (Bio)Processes using Process Systems Engineering (PSE) Methods and Tools
  346. The Virtual Product-Process Design Laboratory for Structured Chemical Product Design and Analysis
  347. Uncertainty Analysis in Raw Material and Utility Cost of Biorefinery Synthesis and Design
  348. Systematic substrate adoption methodology (SAM) for future flexible, generic pharmaceutical production processes
  349. Introducing uncertainty analysis of nucleation and crystal growth models in Process Analytical Technology (PAT) system design of crystallization processes
  350. Model-based analysis of high shear wet granulation from batch to continuous processes in pharmaceutical production – A critical review
  351. A GLUE uncertainty analysis of a drying model of pharmaceutical granules
  352. Advances in the Process Development of Biocatalytic Processes
  353. Process Systems Engineering, 5. Process Dynamics, Control, Monitoring, and Identification
  354. Process Systems Engineering, 1. Introduction
  355. A systematic framework for design of process monitoring and control (PAT) systems for crystallization processes
  356. Benchmark simulation models, quo vadis?
  357. pH variation and influence in an autotrophic nitrogen removing biofilm system using an efficient numerical solution strategy
  358. Microreactors and CFD as Tools for Biocatalysis Reactor Design: A case study
  359. Effect of nitrite, limited reactive settler and plant design configuration on the predicted performance of simultaneous C/N/P removal WWTPs
  360. 3D modelling of coupled mass and heat transfer of a convection-oven roasting process
  361. Calibration and validation of a model describing complete autotrophic nitrogen removal in a granular SBR system
  362. Development of a Population Balance Model of a pharmaceutical drying process and testing of solution methods
  363. Wastewater Treatment Models
  364. Synthesis and design of optimal biorefinery using an expanded network with thermochemical and biochemical biomass conversion platforms
  365. Design of Sustainable Blended Products using an Integrated Methodology
  366. Control of a Biological Nitrogen Removal Process in an Intensified Single Reactor Configuration
  367. A fuzzy-logic based diagnosis and control of a reactor performing complete autotrophic nitrogen removal
  368. Cell mass and cell cycle dynamics of an asynchronous budding yeast population: Experimental observations, flow cytometry data analysis, and multi-scale modeling
  369. Sensitivity analysis of autotrophic N removal by a granule based bioreactor: Influence of mass transfer versus microbial kinetics
  370. Process Systems Engineering, 9. Domain Engineering
  371. Active pharmaceutical ingredient (API) production involving continuous processes – A process system engineering (PSE)-assisted design framework
  372. Lab on a chip automates in vitro cell culturing
  373. Reduction of a single granule drying model: An essential step in preparation of a population balance model with a continuous growth term
  374. Monitoring and control of microbioreactors: An expert opinion on development needs
  375. Overview on Design Considerations for Development of Disposable Microbioreactor Prototypes
  376. Dynamics in population heterogeneity during batch and continuous fermentation of Saccharomyces cerevisiae
  377. Ask the Experts: The challenges and benefits of flow chemistry to optimize drug development
  378. Development of continuous pharmaceutical production processes supported by process systems engineering methods and tools
  379. A framework for model-based optimization of bioprocesses under uncertainty: Lignocellulosic ethanol production case
  380. A perspective on PSE in pharmaceutical process development and innovation
  381. Global sensitivity analysis of the BSM2 dynamic influent disturbance scenario generator
  382. Continuous Hydrolysis and Liquid–Liquid Phase Separation of an Active Pharmaceutical Ingredient Intermediate Using a Miniscale Hydrophobic Membrane Separator
  383. Monitoring and Control of a Continuous Grignard Reaction for the Synthesis of an Active Pharmaceutical Ingredient Intermediate Using Inline NIR spectroscopy
  384. Comparison of laser diffraction and image analysis for measurement of Streptomyces coelicolor cell clumps and pellets
  385. Soft sensors in bioprocessing: A status report and recommendations
  386. Benchmarking biological nutrient removal in wastewater treatment plants: influence of mathematical model assumptions
  387. Mechanistic modelling of the drying behaviour of single pharmaceutical granules
  388. Uncertainty and sensitivity analysis: Mathematical model of coupled heat and mass transfer for a contact baking process
  389. Applying Mechanistic Models in Bioprocess Development
  390. PSE opportunities in biocatalytic process design and development
  391. Computer-Aided Approach for Design of Tailor-Made Blended Products
  392. An Integrated Methodology for Design of Tailor-Made Blended Products
  393. Physiological heterogeneities in microbial populations and implications for physical stress tolerance
  394. Multi-scale modeling for prediction of distributed cellular properties in response to substrate spatial gradients in a continuously run microreactor
  395. Systematic identification of crystallization kinetics within a generic modelling framework
  396. Computational Fluid Dynamics at work - Design and Optimization of Microfluidic Applications
  397. A generic process template for continuous pharmaceutical production
  398. Evaluation of the energy efficiency of enzyme fermentation by mechanistic modeling
  399. Dynamic influent pollutant disturbance scenario generation using a phenomenological modelling approach
  400. Experimental methods and modeling techniques for description of cell population heterogeneity
  401. A Miniature Membrane Reactor for Evaluation of Process Design Options on the Enzymatic Degradation of Pectin
  402. Modelling of coupled heat and mass transfer during a contact baking process
  403. Mechanistic modelling of fluidized bed drying processes of wet porous granules: A review
  404. A generic multi-dimensional model-based system for batch cooling crystallization processes
  405. Wastewater Systems
  406. Introducing process analytical technology (PAT) in filamentous cultivation process development: comparison of advanced online sensors for biomass measurement
  407. Design of tailor-made chemical blend using a decomposition-based computer-aided approach
  408. Systematic procedure for generating operational policies to achieve target crystal size distribution (CSD) in batch cooling crystallization
  409. A Mathematical Model for Simultaneous Saccharification and Co-fermentation (SSCF) of C6 and C5 Sugars
  410. Modeling enzyme production with Aspergillus oryzae in pilot scale vessels with different agitation, aeration, and agitator types
  411. Process analytical technology (PAT) for biopharmaceuticals
  412. A continuous membrane microbioreactor system for development of integrated pectin modification and separation processes
  413. Multienzyme-Catalyzed Processes: Next-Generation Biocatalysis
  414. Ecological Models
  415. Global sensitivity analysis in wastewater treatment plant model applications: Prioritizing sources of uncertainty
  416. A systematic methodology for the design of continuous active pharmaceutical ingredient production processes
  417. Methodological Approach for Modeling of Multienzyme in-pot Processes
  418. A framework for model-based optimization of bioprocesses under uncertainty
  419. PSE in Pharmaceutical Process Development
  420. Dynamic model-based evaluation of process configurations for integrated operation of hydrolysis and co-fermentation for bioethanol production from lignocellulose
  421. Integration of Generic Multi-dimensional Model and Operational Policies for Batch Cooling Crystallization
  422. A retrofit strategy to achieve “Fast, Flexible, Future (F3)” pharmaceutical production processes
  423. Topology optimized microbioreactors
  424. A model-based methodology for simultaneous design and control of a bioethanol production process
  425. A model-based systems approach to pharmaceutical product-process design and analysis
  426. Benchmark Simulation Model No 2: finalisation of plant layout and default control strategy
  427. Assessing reliability of cellulose hydrolysis models to support biofuel process design—Identifiability and uncertainty analysis
  428. An ontological knowledge-based system for the selection of process monitoring and analysis tools
  429. ICAS-PAT: A software for design, analysis and validation of PAT systems
  430. Application of mechanistic models to fermentation and biocatalysis for next-generation processes
  431. Development of a single-use microbioreactor for cultivation of microorganisms
  432. Embedded resistance wire as a heating element for temperature control in microbioreactors
  433. Report and recommendation of a workshop on education and training for measurement, monitoring, modelling and control (M3C) in biochemical engineering
  434. Sensor combination and chemometric variable selection for online monitoring of Streptomyces coelicolor fed-batch cultivations
  435. New framework for standardized notation in wastewater treatment modelling
  436. Online monitoring of fermentation processes in lignocelluloses-to-bioalcohol production
  437. A new extant respirometric assay to estimate intrinsic growth parameters applied to study plasmid metabolic burden
  438. New Framework for Standardized Notation in Wastewater Treatment Modelling
  439. Synthesis, Design and Analysis of Downstream Separation in Bio-refinery Processes through a Group-Contribution Approach
  440. Control of Process Operations and Monitoring of Product Qualities through Generic Model-based in Batch Cooling Crystallization
  441. Contributor contact details
  442. In situ near infrared spectroscopy for analyte-specific monitoring of glucose and ammonium instreptomyces coelicolorfermentations
  443. Evaluation of plant-wide WWTP control strategies including the effects of filamentous bulking sludge
  444. Including the effects of filamentous bulking sludge during the simulation of wastewater treatment plants using a risk assessment model
  445. Wastewater treatment modelling: dealing with uncertainties
  446. On-line estimation of biomass, glucose and ethanol in Saccharomyces cerevisiae cultivations using in-situ multi-wavelength fluorescence and software sensors
  447. Mechanistic models and advanced model analysis within a PAT framework
  448. Monitoring of glucose and ammonium concentration in Streptomyces coelicolor fermentations using in situ Nir
  449. Biorefining: Computer aided tools for sustainable design and analysis of bioethanol production
  450. Application of microbioreactors in fermentation process development: a review
  451. Good modeling practice for PAT applications: Propagation of input uncertainty and sensitivity analysis
  452. Are Mechanistic Cellulose-hydrolysis Models Reliable for Use in Biofuel Process Design?—Identifiability and Sensitivity Analysis
  453. Uncertainty analysis in WWTP model applications: A critical discussion using an example from design
  454. Introducing mechanistic models in Process Analytical Technology education
  455. Uncertainty and sensitivity analysis of control strategies using the benchmark simulation model No1 (BSM1)
  456. Model-based computer-aided framework for design of process monitoring and analysis systems
  457. Application of near-infrared spectroscopy for monitoring and control of cell culture and fermentation
  458. Application of modeling and simulation tools for the evaluation of biocatalytic processes: A future perspective
  459. A software tool for design of process monitoring and analysis systems
  460. Improving the Morris method for sensitivity analysis by scaling the elementary effects
  461. Sensitivity Analysis of Non-Linear Dynamic Models: Prioritizing Experimental Research
  462. A Model-Based Methodology for Simultaneous Design and Control of a Bioethanol Production Process
  463. “Erratum to Editor's name” [Food and Bioproducts Processing (2008) 86 (2), outside back cover and contents list]
  464. Gassed and ungassed power draw in a pilot scale 550 litre fermentor retrofitted with up-pumping hydrofoil B2 impellers in media of different viscosity and with very high power draw
  465. Mixing by rotary jet heads: Indications of the benefits of head rotation under turbulent and transitional flow conditions
  466. Multi-criteria evaluation of wastewater treatment plant control strategies under uncertainty
  467. Risk assessment modelling of microbiology-related solids separation problems in activated sludge systems
  468. Modelling nitrite in wastewater treatment systems: a discussion of different modelling concepts
  469. Matrix notation for efficient development offirst-principlesmodels within PAT applications: Integrated modeling of antibiotic production withStreptomyces coelicolor
  470. Special issue – ECCE-6
  471. Wastewater Treatment Models
  472. Multivariate models for prediction of rheological characteristics of filamentous fermentation broth from the size distribution
  473. Classification and Diagnostic Output Prediction of Cancer Using Gene Expression Profiling and Supervised Machine Learning Algorithms
  474. Off-line design of PAT systems for on-line applications
  475. CAPE methods and tools for systematic analysis of new chemical product design and development
  476. Benchmark simulation model no 2: general protocol and exploratory case studies
  477. Application of multivariable statistical techniques in plant-wide WWTP control strategies analysis
  478. On-line monitoring of fermentation processes using multi-wavelength fluorescence
  479. Artificial neural networks for rapid WWTP performance evaluation: Methodology and case study
  480. ON-LINE ESTIMATION AND DETECTION OF ABNORMAL SUBSTRATE CONCENTRATIONS IN WWTPS USING A SOFTWARE SENSOR: A BENCHMARK STUDY
  481. Benchmark Simulation Model No 2 in Matlab-Simulink: towards plant-wide WWTP control strategy evaluation
  482. Integrated modelling of two xenobiotic organic compounds
  483. Plant-wide (BSM2) evaluation of reject water treatment with a SHARON-Anammox process
  484. Implementing ADM1 for plant-wide benchmark simulations in Matlab/Simulink
  485. Model Reduction Using Neural Networks Applied To The Modeling Of Integrated Urban Wastewater Systems
  486. Extension of the IWA/COST simulation benchmark to include expert reasoning for system performance evaluation
  487. Modelling and control strategy testing of biological and chemical phosphorus removal at Avedøre WWTP
  488. WWTP dynamic disturbance modelling–an essential module for long-term benchmarking development
  489. Demonstration of a tool for automatic learning and re-use of knowledge in the activated sludge process
  490. Efficient modelling necessitates standards for model documentation and exchange
  491. Impact of reactive settler models on simulated WWTP performance
  492. Towards a benchmark simulation model for plant-wide control strategy performance evaluation of WWTPs
  493. MODELLING FOR CONTROL: UNDERSTANDING ROLE AND FUNCTION OF REGULATORY NETWORKS IN MICROORGANISMS
  494. Activated sludge wastewater treatment plant modelling and simulation: state of the art
  495. Benchmarking combined biological phosphorus and nitrogen removal wastewater treatment processes
  496. Transient response of aerobic and anoxic activated sludge activities to sudden substrate concentration changes
  497. A simplified method to assess structurally identifiable parameters in Monod-based activated sludge models
  498. Calibration of Activated Sludge Models: A Critical Review of Experimental Designs
  499. A COMPREHENSIVE MODEL CALIBRATION PROCEDURE FOR ACTIVATED SLUDGE MODELS
  500. Modeling aerobic carbon source degradation processes using titrimetric data and combined respirometric-titrimetric data: Experimental data and model structure
  501. Modeling aerobic carbon source degradation processes using titrimetric data and combined respirometric-titrimetric data: Structural and practical identifiability
  502. Computer aided model analysis and dynamic simulation of a wastewater treatment plant
  503. CONTROL STRATEGY EVALUATION FOR COMBINED N AND P REMOVAL USING A BENCHMARK WASTEWATER TREATMENT PLANT
  504. Activated sludge monitoring with combined respirometric–titrimetric measurements
  505. A COMPREHENSIVE MODEL CALIBRATION PROCEDURE FOR ASM1
  506. A new pH-based procedure to model toxic effects on nitrifiers in activated sludge
  507. Measurement of ammonium concentration and nitrification rate by a new titrimetric biosensor
  508. Sensors to monitor biological nitrogen removal and activated sludge settling
  509. A titration technique for on-line nitrification monitoring in activated sludge
  510. ON-LINE ESTIMATION OF NITROSOMONAS KINETIC PARAMETERS IN ACTIVATED SLUDGE SAMPLES USING TITRATION IN-SENSOR-EXPERIMENTS
  511. Fast and sensitive acute toxicity detection with an enrichment nitrifying culture
  512. New Sensor Based on pH Effect of Denitrification Process
  513. On-Line Nitrification Monitoring in Activated Sludge with a Titrimetric Sensor
  514. Nitrification monitoring in activated sludge by oxygen uptake rate (OUR) measurements
  515. Biosensors for nitrogen control in wastewaters
  516. Nitrification Process Control in Activated Sludge Using Oxygen Uptake Rate Measurements
  517. Organic and ammonium nitrogen and oxygen in relation to granular sludge growth in lab-scale UASB reactors
  518. Towards Understanding the Role and Function of Regulatory Networks in Microorganisms