All Stories

  1. Data fusion of Raman spectra in MSPC for fault detection and diagnosis in pharmaceutical manufacturing
  2. Modernizing non-classical protein crystallization through industry 4.0: Advanced monitoring and modelling utilizing process analytical technology
  3. Accelerating vaccine manufacturing development through model-based approaches: current advances and future opportunities
  4. Water innovation in industrial symbiosis - A global review
  5. Shortcut design method for multicomponent gradient simulated moving beds
  6. A data analytics pipeline to optimize polymer dose strategy in a semi-continuous multi-feed dewatering system
  7. Modelling of industrial-scale bioreactors using the particle lifeline approach
  8. Life cycle assessment of an integrated xylitol biorefinery with value-added co-products
  9. Digital tools in chemical engineering education: The needs and the desires
  10. Designing a fault detection classifier framework for an industrial dynamic ultrafiltration membrane process using wavelet-based feature analysis
  11. Transforming data into actionable knowledge for fault detection, diagnosis and prognosis in urban wastewater systems with AI techniques: A mini-review
  12. Integrated capacity and production planning in the pharmaceutical supply chain: Framework and models
  13. Modelling the impacts of operational conditions on the performance of a full-scale membrane aerated biofilm reactor
  14. The effects of low oxidation-reduction potential on the performance of full-scale hybrid membrane-aerated biofilm reactors
  15. From Paper to web: Students as partners for virtual laboratories in (Bio)chemical engineering education
  16. Simulation-based evaluation of sludge management strategies in a WWTP
  17. Special Issue on “Recent Advances in Population Balance Modeling”
  18. Incremental design of water symbiosis networks with prior knowledge: The case of an industrial park in Kenya
  19. Understanding gradients in industrial bioreactors
  20. Electrochemical tuning of alcohol oxidase and dehydrogenase catalysis via biosensing towards butanol-1 detection in fermentation media
  21. Stochastic simulation-based superstructure optimization framework for process synthesis and design under uncertainty
  22. Transforming data to information: A parallel hybrid model for real‐time state estimation in lignocellulosic ethanol fermentation
  23. Separation of middle boiling trace compounds by distillation: An investigation of practical implications of complex column arrangements on an industrial methanol distillation case study
  24. Towards smart biomanufacturing: a perspective on recent developments in industrial measurement and monitoring technologies for bio-based production processes
  25. Hybrid machine learning assisted modelling framework for particle processes
  26. The Role of Big Data in Industrial (Bio)chemical Process Operations
  27. Automated Electrochemical Glucose Biosensor Platform as an Efficient Tool Toward On-Line Fermentation Monitoring: Novel Application Approaches and Insights
  28. Towards a digital twin: a hybrid data‐driven and mechanistic digital shadow to forecast the evolution of lignocellulosic fermentation
  29. Dynamic model validation and advanced polymer control for rotating belt filtration as primary treatment of domestic wastewaters
  30. Assessment of the fate of organic micropollutants in novel wastewater treatment plant configurations through an empirical mechanistic model
  31. Monitoring yeast fermentations by nonlinear infrared technology and chemometrics—understanding process correlations and indirect predictions
  32. A process synthesis tool for WWTP – An application to design sustainable energy recovery facilities
  33. Distinguishing Commercial Beers Using a Solution-Based Sensor Array Derived from Nanoscale Polydiacetylene Vesicles
  34. Application of Organic-Inorganic Hybrids in Chemical Analysis, Bio- and Environmental Monitoring
  35. Modeling and system identification of an unconventional bioreactor used for single cell protein production
  36. Two novel S1 peptidases from Amycolatopsis keratinophila subsp. keratinophila D2T degrading keratinous slaughterhouse by-products
  37. A novel use for an old problem: The Tennessee Eastman challenge process as an activating teaching tool
  38. Resource recovery from waste streams in a water-energy-food nexus perspective: Toward more sustainable food processing
  39. Towards one-step design of tailored enzymatic nanobiosensors
  40. Model-Based Tools for Pharmaceutical Manufacturing Processes
  41. Flow-following sensors for fermentation processes - an overview
  42. A compartment model for risk-based monitoring of lactic acid bacteria cultivations
  43. Model-based analysis of biocatalytic processes and performance of microbioreactors with integrated optical sensors
  44. From second generation feed-stocks to innovative fermentation and downstream techniques for succinic acid production
  45. Output uncertainty of dynamic growth models: Effect of uncertain parameter estimates on model reliability
  46. Quantitative Flow Cytometry to Understand Population Heterogeneity in Response to Changes in Substrate Availability in Escherichia coli and Saccharomyces cerevisiae Chemostats
  47. An exploration of barriers for commercializing phosphorus recovery technologies
  48. Meta-modeling based efficient global sensitivity analysis for wastewater treatment plants – An application to the BSM2 model
  49. Cleaning of toothpaste from vessel walls by impinging liquid jets and their falling films: quantitative modelling of soaking effects
  50. Benchmarking real-time monitoring strategies for ethanol production from lignocellulosic biomass
  51. Dynamic investigation and modeling of the nitrogen cometabolism in Methylococcus capsulatus ( Bath )
  52. An Industrial Perspective on Scale-Down Challenges Using Miniaturized Bioreactors
  53. Achieving value from process intensification through better process control
  54. Assessing the effects of intra-granule precipitation in a full-scale industrial anaerobic digester
  55. An integrated strategy for the effective production of bristle protein hydrolysate by the keratinolytic filamentous bacterium Amycolatopsis keratiniphila D2
  56. The effect of acetate on population heterogeneity in different cellular characteristics of Escherichia coli in aerobic batch cultures
  57. Evaluation of anaerobic digestion post-treatment options using an integrated model-based approach
  58. Plant-wide model-based analysis of iron dosage strategies for chemical phosphorus removal in wastewater treatment systems
  59. Model-Based Cost Optimization of Double-Effect Water-Lithium Bromide Absorption Refrigeration Systems
  60. A straightforward and easy way to derive a compartment model from a CFD model
  61. Sensors for biosensors: a novel tandem monitoring in a droplet towards efficient screening of robust design and optimal operating conditions
  62. BIOPRO-Sim: A benchmark simulation model for bio-manufacturing processes
  63. Facilitating learning by failure through a pedagogical model-based tool for bioprocesses
  64. Novel strategies for predictive particle monitoring and control using advanced image analysis
  65. Systematic decision-support methodology for identifying promising platform technologies towards circular economy
  66. Towards development of a decision support tool for conceptual design of wastewater treatment plants using stochastic simulation optimization
  67. CFD predicted pH gradients in lactic acid bacteria cultivations
  68. A Genome-Scale Metabolic Model for Methylococcus capsulatus (Bath) Suggests Reduced Efficiency Electron Transfer to the Particulate Methane Monooxygenase
  69. Investigation of the effect of uncertain growth kinetics on a CFD based model for the growth of S. cerevisiae in an industrial bioreactor
  70. Multi-function microfluidic platform for sensor integration
  71. A CFD based automatic method for compartment model development
  72. Economic Risk Analysis and Critical Comparison of Biodiesel Production Systems
  73. Screening of organic solvents for bioprocesses using aqueous-organic two-phase systems
  74. Resource recovery from bio-based production processes in developing Asia
  75. Resource recovery from organic solid waste using hydrothermal processing: Opportunities and challenges
  76. Investigation of the cleaning of egg yolk deposits from tank surfaces using continuous and pulsed flows
  77. Model-based analysis and optimization of a full-scale industrial high-rate anaerobic bioreactor
  78. Key control handles in integrated urban wastewater systems for improving receiving water quality
  79. A Systematic Methodology for Comprehensive Economic Assessment of Process Control Structures
  80. Occurrence, characterisation and fate of (nano)particulate Ti and Ag in two Norwegian wastewater treatment plants
  81. Anomaly Analysis in Cleaning-in-Place Operations of an Industrial Brewery Fermenter
  82. BIOPRO World Talent Campus: A week of real world challenge for biotechnology post-graduate students
  83. A probabilistic model-based soft sensor to monitor lactic acid bacteria fermentations
  84. Developing a framework to model the primary drying step of a continuous freeze-drying process based on infrared radiation
  85. A genome-scale metabolic model for Methylococcus capsulatus predicts reduced efficiency uphill electron transfer to pMMO.
  86. Dynamic Plantwide Modeling, Uncertainty, and Sensitivity Analysis of a Pharmaceutical Upstream Synthesis: Ibuprofen Case Study
  87. “Connecting worlds – a view on microfluidics for a wider application”
  88. Efficient Computational Design of a Scaffold for Cartilage Cell Regeneration
  89. Improved Prediction of Phosphorus Dynamics in Biotechnological Processes by Considering Precipitation and Polyphosphate Formation: A Case Study on Antibiotic Production with Streptomyces coelicolor
  90. Biocatalyst Screening with a Twist: Application of Oxygen Sensors Integrated in Microchannels for Screening Whole Cell Biocatalyst Variants
  91. Mechanistic modeling of cyclic voltammetry: A helpful tool for understanding biosensor principles and supporting design optimization
  92. Caught in-between: System for in-flow inactivation of enzymes as an intermediary step in “plug-and-play” microfluidic platforms
  93. Liquid-to-solid ratio control as an advanced process control solution for continuous twin-screw wet granulation
  94. Configuration optimization of series flow double-effect water-lithium bromide absorption refrigeration systems by cost minimization
  95. Global Sensitivity Analysis as Good Modelling Practices tool for the identification of the most influential process parameters of the primary drying step during freeze-drying
  96. Organic carbon recovery modeling for a rotating belt filter and its impact assessment on a plant-wide scale
  97. Experimental and computational evaluation of area selectively immobilized horseradish peroxidase in a microfluidic device
  98. Model-based process development for a continuous lactic acid bacteria fermentation
  99. A Methodology for Development of a Pedagogical Simulation Tool used in Fermentation Applications
  100. A shortcut approach for decision-making and operational analysis of an integrated end-to-end continuous pharmaceutical process
  101. Modeling for Process Risk Assessment in Industrial Bioprocesses
  102. Enzymatic keratin hydrolysis: Dynamic modelling, parameter estimation and validation
  103. Integrated Process Design and Control of Cyclic Distillation Columns
  104. Exploring the potential of electroless and electroplated noble metal–semiconductor hybrids within bio- and environmental sensing
  105. Implementation of a Radial Basis Function control strategy for the crystallization of Ibuprofen under uncertainty
  106. A fast and simple method to estimate relative, hyphal tensile-strength of filamentous fungi used to assess the effect of autophagy
  107. Quantitative risk assessment via uncertainty analysis in combination with error propagation for the determination of the dynamic Design Space of the primary drying step during freeze-drying
  108. Modelling an industrial anaerobic granular reactor using a multi-scale approach
  109. Evaluation of mixing and mass transfer in a stirred pilot scale bioreactor utilizing CFD
  110. Exploring the effects of ZVI addition on resource recovery in the anaerobic digestion process
  111. Resource recovery from bio-based production processes: a future necessity?
  112. Optimal Design and Planning of Glycerol-Based Biorefinery Supply Chains under Uncertainty
  113. A novel fuzzy-logic control strategy minimizing N 2 O emissions
  114. Mechanistic Fermentation Models for Process Design, Monitoring, and Control
  115. CFD modelling of axial mixing in the intermediate and final rinses of cleaning-in-place procedures of straight pipes
  116. Untargeted GC-MS Metabolomics Reveals Changes in the Metabolite Dynamics of Industrial Scale Batch Fermentations of Streptoccoccus thermophilus Broth
  117. Perspectives on Resource Recovery from Bio-Based Production Processes: From Concept to Implementation
  118. Application of iterative robust model-based optimal experimental design for the calibration of biocatalytic models
  119. A model library for simulation and benchmarking of integrated urban wastewater systems
  120. Understanding N 2 O formation mechanisms through sensitivity analyses using a plant-wide benchmark simulation model
  121. Supply Chain Optimization of Integrated Glycerol Biorefinery: GlyThink Model Development and Application
  122. Adding Value to Bioethanol through a Purification Process Revamp
  123. Plant-wide modelling of phosphorus transformations in wastewater treatment systems: Impacts of control and operational strategies
  124. CFD Modeling of Flow and Ion Exchange Kinetics in a Rotating Bed Reactor System
  125. A novel model-based control strategy for aerobic filamentous fungal fed-batch fermentation processes
  126. Shape optimization as a tool to design biocatalytic microreactors
  127. A review of control strategies for manipulating the feed rate in fed-batch fermentation processes
  128. Dynamic modelling of pectin extraction describing yield and functional characteristics
  129. Removal of benzaldehyde from a water/ethanol mixture by applying scavenging techniques
  130. A Consistent Methodology Based Parameter Estimation for a Lactic Acid Bacteria Fermentation Model
  131. An Efficient Experimental Design Strategy for Modelling and Characterization of Processes
  132. An Empirical Model for Carbon Recovery in a Rotating Belt Filter and Its Application in the Frame of Plantwide Evaluation
  133. Biorefinery Sustainability Analysis
  134. Reverse osmosis for water purification and reuse in the biotechnological industry: Process design, operation and economic guidelines
  135. Uncertainty & sensitivity analysis of economic assessment of lactic acid production from crude glycerol – impact of price correlations
  136. Uncertainty and Sensitivity Analysis for an Ibuprofen Synthesis Model Based on Hoechst Path
  137. ZVI Addition in Continuous Anaerobic Digestion Systems Dramatically Decreases P Recovery Potential: Dynamic Modelling
  138. Assessing the environmental sustainability of early stage design for bioprocesses under uncertainties: An analysis of glycerol bioconversion
  139. Modelling and sensitivity analysis of urinary platinum excretion in anticancer chemotherapy for the recovery of platinum
  140. A flexible well-mixed milliliter-scale reactor with high oxygen transfer rate for microbial cultivations
  141. Generation of synthetic influent data to perform (micro)pollutant wastewater treatment modelling studies
  142. NLP modeling for the optimization of LiBr-H2O absorption refrigeration systems with exergy loss rate, heat transfer area, and cost as single objective functions
  143. Development of in situ product removal strategies in biocatalysis applying scaled-down unit operations
  144. Development of a process map: A step towards a regime map for steady-state high shear wet twin screw granulation
  145. Systematic design of membership functions for fuzzy-logic control: A case study on one-stage partial nitritation/anammox treatment systems
  146. Application of a mechanistic model as a tool for on-line monitoring of pilot scale filamentous fungal fermentation processes-The importance of evaporation effects
  147. Mixing and mass transfer in a pilot scale U-loop bioreactor
  148. A generic model-based methodology for quantification of mass transfer limitations in microreactors
  149. Acceleration of Anti-Markovnikov Hydroamination in the Synthesis of an Active Pharmaceutical Ingredient
  150. Reaction invariant-based reduction of the activated sludge model ASM1 for batch applications
  151. Control structure design for resource recovery using the enhanced biological phosphorus removal and recovery (EBP2R) activated sludge process
  152. Linking granulation performance with residence time and granulation liquid distributions in twin-screw granulation: An experimental investigation
  153. Dynamic optimal foraging theory explains vertical migrations of Bigeye tuna
  154. Economic Risk Assessment of Early Stage Designs for Glycerol Valorization in Biorefinery Concepts
  155. Uncertainty analysis as essential step in the establishment of the dynamic Design Space of primary drying during freeze-drying
  156. A framework for techno-economic & environmental sustainability analysis by risk assessment for conceptual process evaluation
  157. Model-based analysis of a twin-screw wet granulation system for continuous solid dosage manufacturing
  158. Economic risk analysis and critical comparison of optimal biorefinery concepts
  159. Modelling phosphorus (P), sulfur (S) and iron (Fe) interactions for dynamic simulations of anaerobic digestion processes
  160. Catchment & sewer network simulation model to benchmark control strategies within urban wastewater systems
  161. A microfluidic toolbox for the development of in-situ product removal strategies in biocatalysis
  162. Implementation of Near-Infrared Spectroscopy for In-Line Monitoring of a Dehydration Reaction in a Tubular Laminar Reactor
  163. Functional unfold principal component regression methodology for analysis of industrial batch process data
  164. Optimal WWTP process selection for treatment of domestic wastewater – A realistic full-scale retrofitting study
  165. Fulgur: MATLAB GUI application for working with near infrared calibration sets. Part 2: the source code
  166. Modelling and simulation of a U-loop Reactor for Single Cell Protein Production
  167. Mechanistic Models for Process Development and Optimization of Fed-batch Fermentation Systems
  168. Quantifying the importance of flow maldistribution in numbered-up microreactors
  169. Geometry optimization of a fibrous scaffold based on mathematical modelling and CFD simulation of a dynamic cell culture
  170. Economic risk-based analysis: Effect of technical and market price uncertainties on the production of glycerol-based isobutanol
  171. Control of wastewater N2O emissions by balancing the microbial communities using a fuzzy-logic approach
  172. Early-Stage Design and Analysis of Biorefinery Networks
  173. Evaluation of an in-line particle imaging tool for monitoring twin-screw granulation performance
  174. ChemInform Abstract: Process Intensification Tools in the Small-Scale Pharmaceutical Manufacturing of Small Molecules
  175. A plant-wide aqueous phase chemistry module describing pH variations and ion speciation/pairing in wastewater treatment process models
  176. Aeration control by monitoring the microbiological activity using fuzzy logic diagnosis and control. Application to a complete autotrophic nitrogen removal reactor
  177. Process Intensification Tools in the Small-Scale Pharmaceutical Manufacturing of Small Molecules
  178. Microscale technology and biocatalytic processes: opportunities and challenges for synthesis
  179. Upgrading of lignocellulosic biorefinery to value-added chemicals: Sustainability and economics of bioethanol-derivatives
  180. RTD analysis in twin-screw granulation
  181. Effects of ionic strength and ion pairing on (plant-wide) modelling of anaerobic digestion
  182. Effects of influent fractionation, kinetics, stoichiometry and mass transfer on CH4, H2and CO2production for (plant-wide) modeling of anaerobic digesters
  183. Uncertainties in Early-Stage Capital Cost Estimation of Process Design – A Case Study on Biorefinery Design
  184. A mathematical programming framework for early stage design of wastewater treatment plants
  185. Assessment of Recent Process Analytical Technology (PAT) Trends: A Multiauthor Review
  186. Process Analytical Technologies in Biopharmaceutical Process Development
  187. A novel control strategy for single-stage autotrophic nitrogen removal in SBR
  188. Extending the benchmark simulation model n°2 with processes for nitrous oxide production and side-stream nitrogen removal
  189. A Framework for Sustainable Design of Algal Biorefineries: Economic Aspects and Life Cycle Analysis
  190. Fulgur: MATLAB GUI application for working with near infrared calibration sets. Part 1: The Fulgur application
  191. A Perspective on PSE in Fermentation Process Development and Operation
  192. Preface
  193. Fungal Morphology in Industrial Enzyme Production—Modelling and Monitoring
  194. Model-based characterisation of twin-screw granulation system for continuous solid dosage manufacturing
  195. A Numerical Procedure for Model Identifiability Analysis Applied to Enzyme Kinetics
  196. Control Structure Design of an Innovative Enhanced Biological Nutrient Recovery Activated Sludge System Coupled with a Photobioreactor
  197. Model-based optimization of the primary drying step during freeze-drying
  198. Model-Based Analysis and Efficient Operation of a Glucose Isomerization Reactor Plant
  199. Topology optimization for biocatalytic microreactor configurations
  200. State Estimation in Fermentation of Lignocellulosic Ethanol. Focus on the Use of pH Measurements
  201. Multivariate Analysis of Industrial Scale Fermentation Data
  202. Optimal Design of Algae Biorefinery Processing Networks for the production of Protein, Ethanol and Biodiesel
  203. Optimization-based methodology for wastewater treatment plant synthesis – a full scale retrofitting case study
  204. Population balance models: a useful complementary modelling framework for future WWTP modelling
  205. Modelling the occurrence, transport and fate of pharmaceuticals in wastewater systems
  206. Experimental investigation of granule size and shape dynamics in twin-screw granulation
  207. Experimental andin silicoinvestigation of population heterogeneity in continuousSachharomyces cerevisiaescale-down fermentation in a two-compartment setup
  208. Pressure Control in Distillation Columns: A Model-Based Analysis
  209. Filamentous Fungi Fermentation
  210. Challenges encountered when expanding activated sludge models: a case study based on N2O production
  211. Moisture and drug solid-state monitoring during a continuous drying process using empirical and mass balance models
  212. Benchmarking of Control Strategies for Wastewater Treatment Plants
  213. Crystallization Kinetics within a Generic Modeling Framework
  214. A systematic methodology for design of tailor-made blended products
  215. Development of novel control strategies for single-stage autotrophic nitrogen removal: A process oriented approach
  216. Mixing and transport during pharmaceutical twin-screw wet granulation: Experimental analysis via chemical imaging
  217. Comparison of techniques for reconstruction of a distribution from moments in the context of a pharmaceutical drying process
  218. Challenges in industrial fermentation technology research
  219. Effect of Market Price Uncertainties on the Design of Optimal Biorefinery Systems—A Systematic Approach
  220. Influence of selecting secondary settling tank sub-models on the calibration of WWTP models – A global sensitivity analysis using BSM2
  221. Analysing drying unit performance in a continuous pharmaceutical manufacturing line by means of mass – Energy balances
  222. The electrical breakdown of thin dielectric elastomers: thermal effects
  223. Calibration and validation of a phenomenological influent pollutant disturbance scenario generator using full-scale data
  224. Global sensitivity analysis applied to drying models for one or a population of granules
  225. Instrumentation, control and automation in wastewater – from London 1973 to Narbonne 2013
  226. Toward a Computer-Aided Synthesis and Design of Biorefinery Networks: Data Collection and Management Using a Generic Modeling Approach
  227. Balancing effluent quality, economic cost and greenhouse gas emissions during the evaluation of (plant-wide) control/operational strategies in WWTPs
  228. Biocatalytic process development using microfluidic miniaturized systems
  229. Superstructure Development and Optimization under Uncertainty for Design and Retrofit of Municipal Wastewater Treatment Plants
  230. reSystematic Development of Miniaturized (Bio)Processes using Process Systems Engineering (PSE) Methods and Tools
  231. The Virtual Product-Process Design Laboratory for Structured Chemical Product Design and Analysis
  232. Uncertainty Analysis in Raw Material and Utility Cost of Biorefinery Synthesis and Design
  233. Systematic substrate adoption methodology (SAM) for future flexible, generic pharmaceutical production processes
  234. Introducing uncertainty analysis of nucleation and crystal growth models in Process Analytical Technology (PAT) system design of crystallization processes
  235. Model-based analysis of high shear wet granulation from batch to continuous processes in pharmaceutical production – A critical review
  236. A GLUE uncertainty analysis of a drying model of pharmaceutical granules
  237. Advances in the Process Development of Biocatalytic Processes
  238. Process Systems Engineering, 5. Process Dynamics, Control, Monitoring, and Identification
  239. Process Systems Engineering, 1. Introduction
  240. A systematic framework for design of process monitoring and control (PAT) systems for crystallization processes
  241. Benchmark simulation models, quo vadis?
  242. pH variation and influence in an autotrophic nitrogen removing biofilm system using an efficient numerical solution strategy
  243. Microreactors and CFD as Tools for Biocatalysis Reactor Design: A case study
  244. Effect of nitrite, limited reactive settler and plant design configuration on the predicted performance of simultaneous C/N/P removal WWTPs
  245. 3D modelling of coupled mass and heat transfer of a convection-oven roasting process
  246. Calibration and validation of a model describing complete autotrophic nitrogen removal in a granular SBR system
  247. Development of a Population Balance Model of a pharmaceutical drying process and testing of solution methods
  248. Wastewater Treatment Models
  249. Synthesis and design of optimal biorefinery using an expanded network with thermochemical and biochemical biomass conversion platforms
  250. Design of Sustainable Blended Products using an Integrated Methodology
  251. Control of a Biological Nitrogen Removal Process in an Intensified Single Reactor Configuration
  252. A fuzzy-logic based diagnosis and control of a reactor performing complete autotrophic nitrogen removal
  253. Cell mass and cell cycle dynamics of an asynchronous budding yeast population: Experimental observations, flow cytometry data analysis, and multi-scale modeling
  254. Sensitivity analysis of autotrophic N removal by a granule based bioreactor: Influence of mass transfer versus microbial kinetics
  255. Process Systems Engineering, 9. Domain Engineering
  256. Active pharmaceutical ingredient (API) production involving continuous processes – A process system engineering (PSE)-assisted design framework
  257. Lab on a chip automates in vitro cell culturing
  258. Reduction of a single granule drying model: An essential step in preparation of a population balance model with a continuous growth term
  259. Monitoring and control of microbioreactors: An expert opinion on development needs
  260. Overview on Design Considerations for Development of Disposable Microbioreactor Prototypes
  261. Dynamics in population heterogeneity during batch and continuous fermentation of Saccharomyces cerevisiae
  262. Ask the Experts: The challenges and benefits of flow chemistry to optimize drug development
  263. Development of continuous pharmaceutical production processes supported by process systems engineering methods and tools
  264. A framework for model-based optimization of bioprocesses under uncertainty: Lignocellulosic ethanol production case
  265. A perspective on PSE in pharmaceutical process development and innovation
  266. Global sensitivity analysis of the BSM2 dynamic influent disturbance scenario generator
  267. Continuous Hydrolysis and Liquid–Liquid Phase Separation of an Active Pharmaceutical Ingredient Intermediate Using a Miniscale Hydrophobic Membrane Separator
  268. Monitoring and Control of a Continuous Grignard Reaction for the Synthesis of an Active Pharmaceutical Ingredient Intermediate Using Inline NIR spectroscopy
  269. Comparison of laser diffraction and image analysis for measurement of Streptomyces coelicolor cell clumps and pellets
  270. Soft sensors in bioprocessing: A status report and recommendations
  271. Benchmarking biological nutrient removal in wastewater treatment plants: influence of mathematical model assumptions
  272. Mechanistic modelling of the drying behaviour of single pharmaceutical granules
  273. Uncertainty and sensitivity analysis: Mathematical model of coupled heat and mass transfer for a contact baking process
  274. Applying Mechanistic Models in Bioprocess Development
  275. PSE opportunities in biocatalytic process design and development
  276. Computer-Aided Approach for Design of Tailor-Made Blended Products
  277. An Integrated Methodology for Design of Tailor-Made Blended Products
  278. Physiological heterogeneities in microbial populations and implications for physical stress tolerance
  279. Multi-scale modeling for prediction of distributed cellular properties in response to substrate spatial gradients in a continuously run microreactor
  280. Systematic identification of crystallization kinetics within a generic modelling framework
  281. Computational Fluid Dynamics at work - Design and Optimization of Microfluidic Applications
  282. A generic process template for continuous pharmaceutical production
  283. Evaluation of the energy efficiency of enzyme fermentation by mechanistic modeling
  284. Dynamic influent pollutant disturbance scenario generation using a phenomenological modelling approach
  285. Experimental methods and modeling techniques for description of cell population heterogeneity
  286. A Miniature Membrane Reactor for Evaluation of Process Design Options on the Enzymatic Degradation of Pectin
  287. Modelling of coupled heat and mass transfer during a contact baking process
  288. Mechanistic modelling of fluidized bed drying processes of wet porous granules: A review
  289. A generic multi-dimensional model-based system for batch cooling crystallization processes
  290. Wastewater Systems
  291. Introducing process analytical technology (PAT) in filamentous cultivation process development: comparison of advanced online sensors for biomass measurement
  292. Design of tailor-made chemical blend using a decomposition-based computer-aided approach
  293. Systematic procedure for generating operational policies to achieve target crystal size distribution (CSD) in batch cooling crystallization
  294. A Mathematical Model for Simultaneous Saccharification and Co-fermentation (SSCF) of C6 and C5 Sugars
  295. Modeling enzyme production with Aspergillus oryzae in pilot scale vessels with different agitation, aeration, and agitator types
  296. Process analytical technology (PAT) for biopharmaceuticals
  297. A continuous membrane microbioreactor system for development of integrated pectin modification and separation processes
  298. Multienzyme-Catalyzed Processes: Next-Generation Biocatalysis
  299. Ecological Models
  300. Global sensitivity analysis in wastewater treatment plant model applications: Prioritizing sources of uncertainty
  301. A systematic methodology for the design of continuous active pharmaceutical ingredient production processes
  302. Methodological Approach for Modeling of Multienzyme in-pot Processes
  303. A framework for model-based optimization of bioprocesses under uncertainty
  304. PSE in Pharmaceutical Process Development
  305. Dynamic model-based evaluation of process configurations for integrated operation of hydrolysis and co-fermentation for bioethanol production from lignocellulose
  306. Integration of Generic Multi-dimensional Model and Operational Policies for Batch Cooling Crystallization
  307. A retrofit strategy to achieve “Fast, Flexible, Future (F3)” pharmaceutical production processes
  308. Topology optimized microbioreactors
  309. A model-based methodology for simultaneous design and control of a bioethanol production process
  310. A model-based systems approach to pharmaceutical product-process design and analysis
  311. Benchmark Simulation Model No 2: finalisation of plant layout and default control strategy
  312. Assessing reliability of cellulose hydrolysis models to support biofuel process design—Identifiability and uncertainty analysis
  313. An ontological knowledge-based system for the selection of process monitoring and analysis tools
  314. ICAS-PAT: A software for design, analysis and validation of PAT systems
  315. Application of mechanistic models to fermentation and biocatalysis for next-generation processes
  316. Development of a single-use microbioreactor for cultivation of microorganisms
  317. Embedded resistance wire as a heating element for temperature control in microbioreactors
  318. Report and recommendation of a workshop on education and training for measurement, monitoring, modelling and control (M3C) in biochemical engineering
  319. Sensor combination and chemometric variable selection for online monitoring of Streptomyces coelicolor fed-batch cultivations
  320. New framework for standardized notation in wastewater treatment modelling
  321. Online monitoring of fermentation processes in lignocelluloses-to-bioalcohol production
  322. A new extant respirometric assay to estimate intrinsic growth parameters applied to study plasmid metabolic burden
  323. New Framework for Standardized Notation in Wastewater Treatment Modelling
  324. Synthesis, Design and Analysis of Downstream Separation in Bio-refinery Processes through a Group-Contribution Approach
  325. Control of Process Operations and Monitoring of Product Qualities through Generic Model-based in Batch Cooling Crystallization
  326. Contributor contact details
  327. In situ near infrared spectroscopy for analyte-specific monitoring of glucose and ammonium instreptomyces coelicolorfermentations
  328. Evaluation of plant-wide WWTP control strategies including the effects of filamentous bulking sludge
  329. Including the effects of filamentous bulking sludge during the simulation of wastewater treatment plants using a risk assessment model
  330. Wastewater treatment modelling: dealing with uncertainties
  331. On-line estimation of biomass, glucose and ethanol in Saccharomyces cerevisiae cultivations using in-situ multi-wavelength fluorescence and software sensors
  332. Mechanistic models and advanced model analysis within a PAT framework
  333. Monitoring of glucose and ammonium concentration in Streptomyces coelicolor fermentations using in situ Nir
  334. Biorefining: Computer aided tools for sustainable design and analysis of bioethanol production
  335. Application of microbioreactors in fermentation process development: a review
  336. Good modeling practice for PAT applications: Propagation of input uncertainty and sensitivity analysis
  337. Are Mechanistic Cellulose-hydrolysis Models Reliable for Use in Biofuel Process Design?—Identifiability and Sensitivity Analysis
  338. Uncertainty analysis in WWTP model applications: A critical discussion using an example from design
  339. Introducing mechanistic models in Process Analytical Technology education
  340. Uncertainty and sensitivity analysis of control strategies using the benchmark simulation model No1 (BSM1)
  341. Model-based computer-aided framework for design of process monitoring and analysis systems
  342. Application of near-infrared spectroscopy for monitoring and control of cell culture and fermentation
  343. Application of modeling and simulation tools for the evaluation of biocatalytic processes: A future perspective
  344. A software tool for design of process monitoring and analysis systems
  345. Improving the Morris method for sensitivity analysis by scaling the elementary effects
  346. Sensitivity Analysis of Non-Linear Dynamic Models: Prioritizing Experimental Research
  347. A Model-Based Methodology for Simultaneous Design and Control of a Bioethanol Production Process
  348. “Erratum to Editor's name” [Food and Bioproducts Processing (2008) 86 (2), outside back cover and contents list]
  349. Gassed and ungassed power draw in a pilot scale 550 litre fermentor retrofitted with up-pumping hydrofoil B2 impellers in media of different viscosity and with very high power draw
  350. Mixing by rotary jet heads: Indications of the benefits of head rotation under turbulent and transitional flow conditions
  351. Multi-criteria evaluation of wastewater treatment plant control strategies under uncertainty
  352. Risk assessment modelling of microbiology-related solids separation problems in activated sludge systems
  353. Modelling nitrite in wastewater treatment systems: a discussion of different modelling concepts
  354. Matrix notation for efficient development offirst-principlesmodels within PAT applications: Integrated modeling of antibiotic production withStreptomyces coelicolor
  355. Special issue – ECCE-6
  356. Wastewater Treatment Models
  357. Multivariate models for prediction of rheological characteristics of filamentous fermentation broth from the size distribution
  358. Classification and Diagnostic Output Prediction of Cancer Using Gene Expression Profiling and Supervised Machine Learning Algorithms
  359. Off-line design of PAT systems for on-line applications
  360. CAPE methods and tools for systematic analysis of new chemical product design and development
  361. Benchmark simulation model no 2: general protocol and exploratory case studies
  362. Application of multivariable statistical techniques in plant-wide WWTP control strategies analysis
  363. On-line monitoring of fermentation processes using multi-wavelength fluorescence
  364. Artificial neural networks for rapid WWTP performance evaluation: Methodology and case study
  365. ON-LINE ESTIMATION AND DETECTION OF ABNORMAL SUBSTRATE CONCENTRATIONS IN WWTPS USING A SOFTWARE SENSOR: A BENCHMARK STUDY
  366. Benchmark Simulation Model No 2 in Matlab-Simulink: towards plant-wide WWTP control strategy evaluation
  367. Integrated modelling of two xenobiotic organic compounds
  368. Plant-wide (BSM2) evaluation of reject water treatment with a SHARON-Anammox process
  369. Implementing ADM1 for plant-wide benchmark simulations in Matlab/Simulink
  370. Model Reduction Using Neural Networks Applied To The Modeling Of Integrated Urban Wastewater Systems
  371. Extension of the IWA/COST simulation benchmark to include expert reasoning for system performance evaluation
  372. Modelling and control strategy testing of biological and chemical phosphorus removal at Avedøre WWTP
  373. WWTP dynamic disturbance modelling–an essential module for long-term benchmarking development
  374. Demonstration of a tool for automatic learning and re-use of knowledge in the activated sludge process
  375. Efficient modelling necessitates standards for model documentation and exchange
  376. Impact of reactive settler models on simulated WWTP performance
  377. Towards a benchmark simulation model for plant-wide control strategy performance evaluation of WWTPs
  378. MODELLING FOR CONTROL: UNDERSTANDING ROLE AND FUNCTION OF REGULATORY NETWORKS IN MICROORGANISMS
  379. Activated sludge wastewater treatment plant modelling and simulation: state of the art
  380. Benchmarking combined biological phosphorus and nitrogen removal wastewater treatment processes
  381. Transient response of aerobic and anoxic activated sludge activities to sudden substrate concentration changes
  382. A simplified method to assess structurally identifiable parameters in Monod-based activated sludge models
  383. Calibration of Activated Sludge Models: A Critical Review of Experimental Designs
  384. A COMPREHENSIVE MODEL CALIBRATION PROCEDURE FOR ACTIVATED SLUDGE MODELS
  385. Modeling aerobic carbon source degradation processes using titrimetric data and combined respirometric-titrimetric data: Experimental data and model structure
  386. Modeling aerobic carbon source degradation processes using titrimetric data and combined respirometric-titrimetric data: Structural and practical identifiability
  387. Computer aided model analysis and dynamic simulation of a wastewater treatment plant
  388. CONTROL STRATEGY EVALUATION FOR COMBINED N AND P REMOVAL USING A BENCHMARK WASTEWATER TREATMENT PLANT
  389. Activated sludge monitoring with combined respirometric–titrimetric measurements
  390. A COMPREHENSIVE MODEL CALIBRATION PROCEDURE FOR ASM1
  391. A new pH-based procedure to model toxic effects on nitrifiers in activated sludge
  392. Measurement of ammonium concentration and nitrification rate by a new titrimetric biosensor
  393. Sensors to monitor biological nitrogen removal and activated sludge settling
  394. A titration technique for on-line nitrification monitoring in activated sludge
  395. ON-LINE ESTIMATION OF NITROSOMONAS KINETIC PARAMETERS IN ACTIVATED SLUDGE SAMPLES USING TITRATION IN-SENSOR-EXPERIMENTS
  396. Fast and sensitive acute toxicity detection with an enrichment nitrifying culture
  397. New Sensor Based on pH Effect of Denitrification Process
  398. On-Line Nitrification Monitoring in Activated Sludge with a Titrimetric Sensor
  399. Nitrification monitoring in activated sludge by oxygen uptake rate (OUR) measurements
  400. Biosensors for nitrogen control in wastewaters
  401. Nitrification Process Control in Activated Sludge Using Oxygen Uptake Rate Measurements
  402. Organic and ammonium nitrogen and oxygen in relation to granular sludge growth in lab-scale UASB reactors
  403. Towards Understanding the Role and Function of Regulatory Networks in Microorganisms