All Stories

  1. Deciphering Structural Determinants in Chondroitin Sulfate Binding to FGF-2: Paving the Way to Enhanced Predictability of Their Biological Functions

    Article • Polymers, January 2021, MDPI AG

    Dr Eduardo García-Junceda

  2. Unraveling the Structural Landscape of Chitosan-Based Heparan Sulfate Mimics Binding to Growth Factors: Deciphering Structural Determinants for Optimal Activity

    Article • ACS Applied Materials & Interfaces, May 2020, American Chemical Society (ACS)

    Dr Eduardo García-Junceda

  3. Exploring the Origin of Amidase Substrate Promiscuity in CALB by a Computational Approach

    Article • ACS Catalysis, November 2019, American Chemical Society (ACS)

    Dr Eduardo García-Junceda

  4. Simple and Practical Multigram Synthesis of d-Xylonate Using a Recombinant Xylose Dehydrogenase

    Article • ACS Omega, June 2019, American Chemical Society (ACS)

    Dr Eduardo García-Junceda

  5. A holistic approach to unravelling chondroitin sulfation: Correlations between surface charge, structure and binding to growth factors

    Article • Carbohydrate Polymers, December 2018, Elsevier

    Dr Mar Fernandez-Gutierrez, Dr Eduardo García-Junceda

  6. Synthesis, physicochemical characterization and biological evaluation of chitosan sulfate as heparan sulfate mimics

    Article • Carbohydrate Polymers, July 2018, Elsevier

    Dr Eduardo García-Junceda

  7. Front Cover: Phosphorylation Catalyzed by Dihydroxyacetone Kinase (Eur. J. Org. Chem. /2018)

    Article • European Journal of Organic Chemistry, June 2018, Wiley

    Dr Roland Wohlgemuth, Dr Eduardo García-Junceda

  8. Phosphorylation Catalyzed by Dihydroxyacetone Kinase

    Article • European Journal of Organic Chemistry, May 2018, Wiley

    Dr Roland Wohlgemuth, Dr Eduardo García-Junceda

  9. Assembly of glycoamino acid building blocks: a new strategy for the straightforward synthesis of heparan sulfate mimics

    Article • Chemical Communications, January 2018, Royal Society of Chemistry

    Dr Eduardo García-Junceda

  10. Biocatalysis in Spain: A field of success and innovation

    Article • Biocatalysis and Biotransformation, December 2017, Taylor & Francis

    Professor Andres R. Alcantara, Dr Eduardo García-Junceda

  11. Computational study of the phosphoryl donor activity of dihydroxyacetone kinase from ATP to inorganic polyphosphate

    Article • International Journal of Quantum Chemistry, October 2017, Wiley

    Dr Eduardo García-Junceda

  12. Highly improved enzymatic peptide synthesis by using biphasic reactors

    Article • Biocatalysis and Biotransformation, May 2017, Taylor & Francis

    Professor JOSE M. GUISAN, Dr Eduardo García-Junceda

  13. Analytical Validation of a New Enzymatic and Automatable Method for d-Xylose Measurement in Human Urine Samples

    Article • BioMed Research International, January 2017, Hindawi Publishing Corporation

    Dr Eduardo García-Junceda

  14. Development of a new method for d -xylose detection and quantification in urine, based on the use of recombinant xylose dehydrogenase from Caulobacter crescentus

    Article • Journal of Biotechnology, September 2016, Elsevier

    Dr Eduardo García-Junceda

  15. 6-O-Nucleotidyltransferase: an aminoglycoside-modifying enzyme specific for streptomycin/streptidine

    Article • MedChemComm, January 2016, Royal Society of Chemistry

    Dr Eduardo García-Junceda

  16. Tuning the Phosphoryl Donor Specificity of Dihydroxyacetone Kinase from ATP to Inorganic Polyphosphate. An Insight from Computational Studies

    Article • International Journal of Molecular Sciences, November 2015, MDPI AG

    Dr Eduardo García-Junceda

  17. L-Rhamnulose-1-phosphate Aldolase fromThermotoga maritimain Organic Synthesis: One-Pot Multistep Reactions for the Preparation of Imino- and Nitrocyclitols

    Article • Advanced Synthesis & Catalysis, May 2015, Wiley

    Dr Eduardo García-Junceda

  18. (Chemo)enzymatic cascades—Nature's synthetic strategy transferred to the laboratory

    Article • Journal of Molecular Catalysis B Enzymatic, April 2015, Elsevier

    Dr Ivan Lavandera, Dr Eduardo García-Junceda

  19. l-Rhamnulose-1-phosphate and l-fuculose-1-phosphate aldolase mediated multi-enzyme cascade systems for nitrocyclitol synthesis

    Article • Journal of Molecular Catalysis B Enzymatic, April 2015, Elsevier

    Dr Eduardo García-Junceda

  20. Hyperthermophilic aldolases as biocatalyst for C–C bond formation: rhamnulose 1-phosphate aldolase from Thermotoga maritima

    Article • Applied Microbiology and Biotechnology, October 2014, Springer Science + Business Media

    Dr Eduardo García-Junceda

  21. Dihydroxyacetone-catalyzed phosphorylation

    Article • New Biotechnology, July 2014, Elsevier

    Dr Roland Wohlgemuth, Prof. Dr. Roland Wohlgemuth, Dr Eduardo García-Junceda

  22. Aryl Sulfotransferase fromHaliangium ochraceum: A Versatile Tool for the Sulfation of Small Molecules

    Article • ChemCatChem, March 2014, Wiley

    Dr Eduardo García-Junceda

  23. Corrigendum to “Enzyme catalysed tandem reactions” [Curr Opin Chem Biol 17 (2013) 236–249]

    Article • Current Opinion in Chemical Biology, December 2013, Elsevier

    Dr Eduardo García-Junceda

  24. Enzyme catalysed tandem reactions

    Article • Current Opinion in Chemical Biology, April 2013, Elsevier

    Dr Eduardo García-Junceda

  25. One-Pot Cascade Reactions using Fructose-6-phosphate Aldolase: Efficient Synthesis of D-Arabinose 5-Phosphate, D-Fructose 6-Phosphate and Analogues

    Article • Advanced Synthesis & Catalysis, June 2012, Wiley

    Dr Eduardo García-Junceda, Dr Roland Wohlgemuth

  26. 7.20 Multi-Enzyme Reactions

    Article • January 2012, Elsevier

    Dr Eduardo García-Junceda

  27. Synthesis and evaluation of xylopyranoside derivatives as “decoy acceptors” of human β-1,4-galactosyltransferase 7

    Article • Molecular BioSystems, January 2011, Royal Society of Chemistry

    Dr Eduardo García-Junceda

  28. Preparation and Characterization of a Bifunctional Aldolase/Kinase Enzyme: A More Efficient Biocatalyst for CC Bond Formation

    Article • Chemistry - A European Journal, March 2010, Wiley

    Dr Eduardo García-Junceda

  29. Activated α,β-Unsaturated Aldehydes as Substrate of Dihydroxyacetone Phosphate (DHAP)-Dependent Aldolases in the Context of a Multienzyme System

    Article • Advanced Synthesis & Catalysis, November 2009, Wiley

    Dr Eduardo García-Junceda

  30. Cloning and expression of a putative rhamnulose-1-phosphate aldolase from the hyperthermophilic eubacterium Thermotoga maritima

    Article • New Biotechnology, September 2009, Elsevier

    Dr Eduardo García-Junceda

  31. Design and development of multi-enzyme systems for facile and efficient C–C bond formation

    Article • New Biotechnology, September 2009, Elsevier

    Dr Eduardo García-Junceda

  32. From Kinase to Cyclase: An Unusual Example of Catalytic Promiscuity Modulated by Metal Switching

    Article • ChemBioChem, January 2009, Wiley

    Dr Eduardo García-Junceda

  33. Substrate channelling in an engineered bifunctional aldolase/kinase enzyme confers catalytic advantage for C–C bond formation

    Article • Chemical Communications, January 2009, Royal Society of Chemistry

    Dr Eduardo García-Junceda

  34. Multi‐Step Enzyme Catalysis

    Article • September 2008, Wiley

    Dr Eduardo García-Junceda

  35. Rescue of the streptomycin antibiotic activity by using streptidine as a “decoy acceptor” for the aminoglycoside-inactivating enzyme adenyl transferase

    Article • Chemical Communications, January 2007, Royal Society of Chemistry

    Dr Eduardo García-Junceda

  36. Exploring the Use of Conformationally Locked Aminoglycosides as a New Strategy to Overcome Bacterial Resistance

    Article • Journal of the American Chemical Society, January 2006, American Chemical Society (ACS)

    Dr Jose Luis Chiara, Dr Eduardo García-Junceda

  37. Molecular Recognition of Aminoglycoside Antibiotics by Bacterial Defence Proteins: NMR Study of the Structural and Conformational Features of Streptomycin Inactivation byBacillus subtilis Aminoglycoside-6-adenyl Transferase

    Article • Chemistry - A European Journal, August 2005, Wiley

    Dr Eduardo García-Junceda

  38. A Simple Structural-Based Approach to Prevent Aminoglycoside Inactivation by Bacterial Defense Proteins. Conformational Restriction Provides Effective Protection against Neomycin-B Nucleotidylation by ANT4

    Article • Journal of the American Chemical Society, June 2005, American Chemical Society (ACS)

    Dr Jose Luis Chiara, Dr Eduardo García-Junceda

  39. Structure / Activity Relationship of Carba- and C-Fucopyranosides as Inhibitors of an α 1,6-Fucosyltransferase by Molecular Modeling and Kinetic Studies

    Article • Letters in Organic Chemistry, May 2005, Bentham Science Publishers

    Dr Eduardo García-Junceda

  40. Multienzyme System for Dihydroxyacetone Phosphate-Dependent Aldolase Catalyzed C—C Bond Formation from Dihydroxyacetone.

    Article • ChemInform, November 2004, Wiley

    Dr Eduardo García-Junceda

  41. Enzymes in the synthesis of bioactive compounds

    Article • Bioorganic & Medicinal Chemistry, April 2004, Elsevier

    Dr Eduardo García-Junceda

  42. Multienzyme system for dihydroxyacetone phosphate-dependent aldolase catalyzed C–C bond formation from dihydroxyacetone

    Article • Chemical Communications, January 2004, Royal Society of Chemistry

    Dr Eduardo García-Junceda

  43. In Vivo Chaperone-Assisted Folding of α-1,6-Fucosyltransferase from Rhizobium sp.

    Article • ChemBioChem, June 2003, Wiley

    Dr Eduardo García-Junceda

  44. C-Terminal truncation of α 1,6-fucosyltransferase from Rhizobium sp. does not annul the transferase activity of the enzyme

    Article • Bioorganic & Medicinal Chemistry, March 2002, Elsevier

    Dr Eduardo García-Junceda

  45. Synthesis of Carba- and C-Fucopyranosides and Their Evaluation as α-Fucosidase Inhibitors − Analysis of an Unusual Conformation Adopted by an Amino-C-fucopyranoside

    Article • European Journal of Organic Chemistry, November 2001, Wiley

    Dr Eduardo García-Junceda

  46. Heterologous Over-expression ofα-1,6-Fucosyltransferase fromRhizobium sp.: Application to the Synthesis of the Trisaccharideβ-D-GlcNAc(1→4)- [α-L-Fuc-(1→6)]-D-GlcNAc, Study of the Acceptor Specificity and Evaluation of Polyhydroxylated Indolizidines as...

    Article • Chemistry - A European Journal, June 2001, Wiley

    Dr Eduardo García-Junceda

  47. Enzymatic synthesis of disaccharides by β-galactosidase-catalyzed glycosylation of a glycocluster

    Article • Journal of Molecular Catalysis B Enzymatic, December 2000, Elsevier

    Dr Eduardo García-Junceda

  48. A New Strategy for Liquid-Phase Synthesis of Disaccharides Based on the Use of Glycosidases

    Article • Biocatalysis and Biotransformation, January 2000, Taylor & Francis

    Dr Eduardo García-Junceda

  49. Enzymic Synthesis of L-Fucose and Analogs

    Article • The Journal of Organic Chemistry, November 1995, American Chemical Society (ACS)

    Dr Eduardo García-Junceda

  50. Cloning and overexpression of rhamnose isomerase and fucose isomerase

    Article • Bioorganic & Medicinal Chemistry, October 1995, Elsevier

    Dr Eduardo García-Junceda

  51. Enzymic Synthesis and Regeneration of 3'-Phosphoadenosine 5'-Phosphosulfate (PAPS) for Regioselective Sulfation of Oligosaccharides

    Article • Journal of the American Chemical Society, August 1995, American Chemical Society (ACS)

    Dr Eduardo García-Junceda

  52. A new strategy for the cloning, overexpression and one step purification of three DHAP-dependent aldolases: Rhamnulose-1-phosphate aldolase, fuculose-1-phosphate aldolase and tagatose-1,6-diphosphate aldolase1

    Article • Bioorganic & Medicinal Chemistry, July 1995, Elsevier

    Dr Eduardo García-Junceda

  53. A Short Enzymic Synthesis of L-Glucose from Dihydroxyacetone Phosphate and L-Glyceraldehyde

    Article • The Journal of Organic Chemistry, June 1995, American Chemical Society (ACS)

    Dr Eduardo García-Junceda

  54. Crystallization and preliminary crystallographic data for class I deoxyribose-5-phosphate aldolase fromEscherichia coli: An Application of Reverse Screening

    Article • Proteins Structure Function and Bioinformatics, May 1995, Wiley

    Dr Eduardo García-Junceda

  55. Recombinant 2-Deoxyribose-5-phosphate Aldolase in Organic Synthesis: Use of Sequential Two-Substrate and Three-Substrate Aldol Reactions

    Article • Journal of the American Chemical Society, March 1995, American Chemical Society (ACS)

    Dr Eduardo García-Junceda

  56. Large scale production of recombinant .alpha.-1,2-mannosyltransferase from E. coli for the study of acceptor specificity and use of the recombinant whole cells in synthesis

    Article • The Journal of Organic Chemistry, October 1994, American Chemical Society (ACS)

    Dr Eduardo García-Junceda

  57. Cloning, overexpression and isolation of the type II FDP aldolase from E. coli for specificity study and synthetic application

    Article • Bioorganic & Medicinal Chemistry, August 1994, Elsevier

    Dr Eduardo García-Junceda

  58. Chemical-enzymic synthesis and conformational analysis of sialyl Lewis X and derivatives

    Article • Journal of the American Chemical Society, November 1992, American Chemical Society (ACS)

    Dr Eduardo García-Junceda

  59. Kinetic comparison between soluble and polyacrylamide-entrapped depsidone ether hydrolase from the lichen Pseudevernia furfuracea

    Article • Plant Science, January 1992, Elsevier

    Dr Eduardo García-Junceda

  60. Kinetics and stability of an immobilized orsellinate depside hydrolase in polyacrylamide gel

    Article • Enzyme and Microbial Technology, March 1991, Elsevier

    Dr Eduardo García-Junceda

  61. Enzymatic hydrolysis of physodic acid in Pseudevernia furfuracea. Characterization of the product of depsidone hydrolysis

    Article • Plant Science, January 1991, Elsevier

    Dr Eduardo García-Junceda

  62. Photosynthetical and nutritional implications in the accumulation of phenols in the lichen Pseudevernia furfuracea

    Article • Biochemical Systematics and Ecology, May 1987, Elsevier

    Dr Eduardo García-Junceda

  63. The use of immobilized cells to stabilize orsellinate depside hydrolase of Pseudevernia furfuracea

    Article • Plant Cell Reports, April 1986, Springer Science + Business Media

    Dr Eduardo García-Junceda

  64. Dihydroxyacetone Phosphate-Dependent Aldolases in the Core of Multi-Step Processes

    Article • Wiley

    Dr Eduardo García-Junceda