Professor Patrick Van Dijck
Katholieke Universiteit Leuven
Professor, Life Sciences
Belgium
My co-authors include
Professor Tom Coenye
Ive De De Smet
Dr. Adam F. Feyaerts
My Publications
Let’s shine a light on fungal infections: A noninvasive imaging toolbox
PLoS Pathogens
March 2020
Three-Dimensional Visualization of APEX2-Tagged Erg11 in Saccharomyces cerevisiae Using...
mSphere
February 2020
Transcriptional responses of Candida glabrata biofilm cells to fluconazole are modulate...
npj Biofilms and Microbiomes
January 2020
Impact of nanosystems in Staphylococcus aureus biofilms treatment
FEMS Microbiology Reviews
August 2019
Mitogen-Activated Protein Kinase Cross-Talk Interaction Modulates the Production of Mel...
mBio
March 2019
Inhibition of Vesicular Transport Influences Fungal Susceptibility to Fluconazole
Antimicrobial Agents and Chemotherapy
February 2019
Candidalysin Crucially Contributes to Nlrp3 Inflammasome Activation by Candida albicans...
mBio
January 2019
Monitoring of Fluconazole and Caspofungin Activity against In Vivo Candida glabrata Bio...
Antimicrobial Agents and Chemotherapy
November 2018
Fungal persister cells: The basis for recalcitrant infections?
PLoS Pathogens
October 2018
A High-ThroughputCandida albicansTwo-Hybrid System
mSphere
August 2018
Fire blight host-pathogen interaction: proteome profiles of Erwinia amylovora infecting...
Scientific Reports
August 2018
Anidulafungin increases the antibacterial activity of tigecycline in polymicrobial Cand...
Journal of Antimicrobial Chemotherapy
July 2018
Bioluminescence imaging increases in vivo screening efficiency for antifungal activity ...
International Journal of Antimicrobial Agents
July 2018
Introducing fluorescence resonance energy transfer-based biosensors for the analysis of...
Cellular Microbiology
June 2018
Antifungal Activity and Synergism with Azoles of Polish Propolis
Pathogens
June 2018
Candida glabrata’s Genome Plasticity Confers a Unique Pattern of Expressed Cell Wall Pr...
Journal of Fungi
June 2018
Antifungal Activity and Synergism with Azoles of Polish Propolis
May 2018
Fungal G-protein-coupled receptors: mediators of pathogenesis and targets for disease c...
Nature Microbiology
March 2018
Essential oils and their components are a class of antifungals with potent vapour-phase...
Scientific Reports
March 2018
Methionine is required for cAMP-PKA mediated morphogenesis and virulence of Candida alb...
Molecular Microbiology
February 2018
Antifungal Activity of Oleylphosphocholine on In Vitro and In Vivo Candida albicans Bio...
Antimicrobial Agents and Chemotherapy
October 2017
Comparison of genome engineering using the CRISPR-Cas9 system in C. glabrata wild-typ...
Fungal Genetics and Biology
October 2017
Modulation of Staphylococcus aureus Response to Antimicrobials by the Candida albicans ...
Antimicrobial Agents and Chemotherapy
September 2017
A Bimolecular Fluorescence Complementation Tool for Identification of Prot...
G3 Genes|Genomes|Genetics
August 2017
Mitochondrial Cochaperone Mge1 Is Involved in Regulating Susceptibility to Fluconazole ...
mBio
July 2017
Be careful for false positive results caused by volatiles!
Flavour and Fragrance Journal
July 2017
A signaling cascade linking CO2 sensing and lipid signaling in fungi
mBio
January 2017
Characterization of the Candida albicans Amino Acid Permease Family: Gap2 Is the Only G...
mSphere
December 2016
The antifungal caspofungin increases fluoroquinolone activity against Staphylococcus au...
Nature Communications
November 2016
Commensal Protection ofStaphylococcus aureusagainst Antimicrobials byCandida albicansBi...
mBio
October 2016
Transcription Factor Arabidopsis Activating Factor1 Integrates Carbon Starvation Respon...
PLANT PHYSIOLOGY
July 2015
Deletion of the DNA Ligase IV Gene in Candida glabrata Significantly Increases Gene-Tar...
Eukaryotic Cell
June 2015
Trehalose-6-phosphate synthase 1 is not the only active TPS in Arabidopsis thaliana
Biochemical Journal
March 2015
Force Nanoscopy of Hydrophobic Interactions in the Fungal Pathogen Candida glabrata
ACS Nano
February 2015
<em>Candida albicans</em> Biofilm Development on Medically-relevant Foreign Bodies in a...
Journal of Visualized Experiments
January 2015
Clinical Implications of Oral Candidiasis: Host Tissue Damage and Disseminated Bacteria...
Infection and Immunity
November 2014
In vivo Candida glabrata biofilm development on foreign bodies in a rat subcutaneous model
Journal of Antimicrobial Chemotherapy
November 2014
Oral Administration of the Broad-Spectrum Antibiofilm Compound Toremifene Inhibits Cand...
Antimicrobial Agents and Chemotherapy
October 2014
Functional screening of a cDNA library from the desiccation-tolerant plant Selaginella ...
Journal of Plant Research
September 2014
Duplication of a promiscuous transcription factor drives the emergence of a new regulat...
Nature Communications
September 2014
Ascorbic Acid Inhibition of Candida albicans Hsp90-Mediated Morphogenesis Occurs via th...
Eukaryotic Cell
August 2014
The desiccation tolerant secrets of Selaginella lepidophylla: What we have learned so far?
Plant Physiology and Biochemistry
July 2014
Molecular mechanisms of antimicrobial tolerance and resistance in bacterial and fungal ...
Trends in Microbiology
June 2014
Trehalose metabolism in plants
The Plant Journal
May 2014
Fine tuning of trehalose biosynthesis and hydrolysis as novel tools for the generation ...
Frontiers in Plant Science
April 2014
Cool Tools 1: Development and Application of a Candida albicans Two-Hybrid System
April 2014
Microbial biofilms - the coming of age of a research field
Pathogens and Disease
April 2014
Candida Biofilms and the Host: Models and New Concepts for Eradication
February 2014
Microbial cell surface proteins and secreted metabolites involved in multispecies biofilms
Pathogens and Disease
January 2014
Quantifying the Forces Driving Cell–Cell Adhesion in a Fungal Pathogen
Langmuir
November 2013
Mammalian ribosomal and chaperone protein RPS3A counteracts α-synuclein aggregation and...
Biochemical Journal
November 2013
Bioluminescence Imaging of Fungal Biofilm Development in Live Animals
October 2013
Towards non-invasive monitoring of pathogen-host interactions duringCandida albicansbio...
Cellular Microbiology
September 2013
Recent insights into Candida albicans biofilm resistance mechanisms
Current Genetics
August 2013
Relevance of Trehalose in Pathogenicity: Some General Rules, Yet Many Exceptions
PLoS Pathogens
August 2013
Redundant and non-redundant roles of the trehalose-6-phosphate phosphatases in leaf gro...
Plant Signaling & Behavior
March 2013
Activities of Systemically Administered Echinocandins againstIn VivoMature Candida albi...
Antimicrobial Agents and Chemotherapy
February 2013
Overexpression of the Trehalase Gene AtTRE1 Leads to Increased Drought Stress Tolerance...
PLANT PHYSIOLOGY
January 2013
Single-cell force spectroscopy of the medically important Staphylococcus epidermidis–Ca...
Nanoscale
January 2013
Oriented Polar Snakes for Phase Contrast Cell Images Segmentation
January 2013
Metabolic engineering of Kluyveromyces lactis for L-ascorbic acid (vitamin C) biosynthesis
Microbial Cell Factories
January 2013
Single-Molecule Imaging and Functional Analysis of Als Adhesins and Mannans during Cand...
ACS Nano
November 2012
The Nonsteroidal Antiinflammatory Drug Diclofenac Potentiates the In Vivo Activity of C...
The Journal of Infectious Diseases
September 2012
Loss-of-function mutations in HINT1 cause axonal neuropathy with neuromyotonia
Nature Genetics
September 2012
Tight Control of Trehalose Content Is Required for Efficient Heat-induced Cell Elongati...
Journal of Biological Chemistry
September 2012
Expansive Evolution of the TREHALOSE-6-PHOSPHATE PHOSPHATASE Gene Family in Arabidopsis
PLANT PHYSIOLOGY
August 2012
Diversity in Genetic In Vivo Methods for Protein-Protein Interaction Studies: from the ...
Microbiology and Molecular Biology Reviews
June 2012
The Heat-Induced Molecular Disaggregase Hsp104 of Candida albicans Plays a Role in Biof...
Eukaryotic Cell
May 2012
Potent Synergistic Effect of Doxycycline with Fluconazole against Candida albicans Is M...
Antimicrobial Agents and Chemotherapy
May 2012
Transcription factor Efg1 contributes to the tolerance of Candida albicans biofilms aga...
Journal of Medical Microbiology
March 2012
Heterozygous missense mutations in SMARCA2 cause Nicolaides-Baraitser syndrome
Nature Genetics
February 2012
CandidaBiofilms and the Host: Models and New Concepts for Eradication
International Journal of Microbiology
January 2012
The Candida albicans GAP Gene Family Encodes Permeases Involved in General and Specific...
Eukaryotic Cell
July 2011
Detailed comparison of Candida albicans and Candida glabrata biofilms under different c...
Journal of Medical Microbiology
May 2011
How Do Sugars Regulate Plant Growth?
Frontiers in Plant Science
January 2011
Mutations in the SPTLC2 Subunit of Serine Palmitoyltransferase Cause Hereditary Sensory...
The American Journal of Human Genetics
October 2010
Candida albicans Pde1p and Gpa2p comprise a regulatory module mediating agonist-induced...
Fungal Genetics and Biology
September 2010
A CUG codon adapted two-hybrid system for the pathogenic fungus Candida albicans
Nucleic Acids Research
August 2010
In Vivo Efficacy of Anidulafungin against Mature Candida albicans Biofilms in a Novel R...
Antimicrobial Agents and Chemotherapy
July 2010
Effect of antifungals on itraconazole resistant Candida glabrata
Open Life Sciences
June 2010
A Single Active Trehalose-6-P Synthase (TPS) and a Family of Putative Regulatory TPS-Li...
Molecular Plant
March 2010
Real-time PCR expression profiling of genes encoding potential virulence factors in Can...
BMC Microbiology
January 2010
Stress Tolerance of the <i>Saccharomyces cerevisiae</i> Adenylate Cyclase <i>fil1</i> (...
Journal of Molecular Microbiology and Biotechnology
January 2010
Candida albicans biofilm formation in a new in vivo rat model
Microbiology
December 2009
Nutrient sensing G protein-coupled receptors: interesting targets for antifungals?
Medical Mycology
November 2009
The Cytophaga hutchinsonii ChTPSP: First Characterized Bifunctional TPS-TPP Protein as ...
Molecular Biology and Evolution
October 2009
Extensive expression regulation and lack of heterologous enzymatic activity of the Cla...
Plant Cell & Environment
August 2009
Dominant mutations in the tyrosyl-tRNA synthetase gene recapitulate in <i>D...
Proceedings of the National Academy of Sciences
July 2009
Small G proteins in peroxisome biogenesis: the potential involvement of ADP-ribosylatio...
BMC Cell Biology
January 2009
Nutrient sensing G protein-coupled receptors: interesting targets for antifungals?
Medical Mycology
January 2009
Extracting expression modules from perturbational gene expression compendia
BMC Systems Biology
April 2008
Flavour formation in fungi: characterisation of KlAtf, the Kluyveromyces lactis ortholo...
Applied Microbiology and Biotechnology
April 2008
Identification of Hexose Transporter-Like Sensor HXS1 and Functional Hexose Transporter...
Eukaryotic Cell
February 2008
Combined Inactivation of the Candida albicans GPR1 and TPS2 Genes Results in Avirulence...
Infection and Immunity
February 2008
Parameters Affecting Ethyl Ester Production by Saccharomyces cerevisiae during Fermenta...
Applied and Environmental Microbiology
November 2007
Trehalose-6-P synthase AtTPS1 high molecular weight complexes in yeast and Arabidopsis
Plant Science
October 2007
A bifunctional TPS–TPP enzyme from yeast confers tolerance to multiple and extreme abio...
Planta
July 2007
Environmental Sensing and Signal Transduction Pathways Regulating Morphopathogenic Dete...
Microbiology and Molecular Biology Reviews
June 2007
Improved drought tolerance without undesired side effects in transgenic plants producin...
Plant Molecular Biology
April 2007
Attachment ofMAL32-encoded maltase on the outside of yeast cells improves maltotriose u...
Yeast
January 2007
2.306 A yeast-based screening system for mouse brain proteins that modify the toxicity ...
Parkinsonism & Related Disorders
January 2007
2.308 Characterization of the expression of alpha-synuclein and suppressor/enhancer pro...
Parkinsonism & Related Disorders
January 2007
Isolation and Characterization of Brewer's Yeast Variants with Improved Fermentation Pe...
Applied and Environmental Microbiology
December 2006
Immunogold localization of trehalose-6-phosphate synthase in leaf segments of wild-type...
PROTOPLASMA
November 2006
ABI4 mediates the effects of exogenous trehalose on Arabidopsis growth and starch break...
Plant Molecular Biology
September 2006
P3-158
Alzheimer s & Dementia
July 2006
Why do microorganisms have aquaporins?
Trends in Microbiology
February 2006
Trehalose-6-phosphate synthase as an intrinsic selection marker for plant transformation
Journal of Biotechnology
February 2006
Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominan...
Nature Genetics
January 2006
Physiological and Molecular Responses of Yeasts to the Environment
January 2006
Transformation of tobacco with an Arabidopsis thaliana gene involved in trehalose biosy...
Euphytica
November 2005
Aquaporin Expression and Freeze Tolerance in Candida albicans
Applied and Environmental Microbiology
October 2005
Nutrient sensing systems for rapid activation of the protein kinase A pathway in yeast
Biochemical Society Transactions
February 2005
Carbon source induced yeast-to-hypha transition in Candida albicans is dependent on th...
Biochemical Society Transactions
February 2005
Heterologous Aquaporin (<i>AQY2–1</i>) Expression Strongly Enhances Freeze Tolerance of...
Journal of Molecular Microbiology and Biotechnology
January 2005
Glucose and Sucrose Act as Agonist and Mannose as Antagonist Ligands of the G Protein-C...
Molecular Cell
October 2004
Glucose and sucrose: hazardous fast-food for industrial yeast?
Trends in Biotechnology
October 2004
Aquaporin-Mediated Improvement of Freeze Tolerance of Saccharomyces cerevisiae Is Restr...
Applied and Environmental Microbiology
June 2004
The high general stress resistance of theSaccharomyces cerevisiae fil1 adenylate cyclas...
Yeast
January 2004
Trehalose Metabolism: Enzymatic Pathways and Physiological Functions
January 2004
Progress in functional genomics approaches to antifungal drug target discovery
Trends in Microbiology
October 2003
Uncoupling of the glucose growth defect and the deregulation of glycolysis in Saccharom...
Biochimica et Biophysica Acta (BBA) - Bioenergetics
September 2003
Activation state of protein kinase A as measured in permeabilised Saccharomyces cerevis...
FEMS Yeast Research
March 2003
Corrigendum to âActivation state of protein kinase A as measured in permeabilised Sac...
FEMS Yeast Research
March 2003
Determinants of Freeze Tolerance in Microorganisms, Physiological Importance, and Biote...
January 2003
Aquaporin Expression Correlates with Freeze Tolerance in Baker's Yeast, and Overexpress...
Applied and Environmental Microbiology
December 2002
Isolation and Characterization of a Freeze-Tolerant Diploid Derivative of an Industrial...
Applied and Environmental Microbiology
October 2002
Truncation of Arabidopsis thaliana and Selaginella lepidophylla trehalose-6-phosphate s...
Biochemical Journal
August 2002
Disruption of the Candida albicans TPS2 Gene Encoding Trehalose-6-Phosphate Phosphatase...
Infection and Immunity
April 2002
Functional Genomics Approaches for the Identification and Validation of Antifungal Drug...
American Journal of PharmacoGenomics
January 2002
An unexpected plethora of trehalose biosynthesis genes in Arabidopsis thaliana
Trends in Plant Science
November 2001
Identification of two related genes responsible for improved freeze-resistance in baker...
BMC News and views
June 2001
Expression of Escherichia coli otsA in a Saccharomyces cerevisiae tps1 mutant restores ...
Biochemical Journal
August 2000
Nutrient-induced signal transduction through the protein kinase A pathway and its role ...
Enzyme and Microbial Technology
June 2000
A specific mutation in Saccharomyces cerevisiae adenylate cyclase, Cyr1K1876M, eliminat...
International Journal of Food Microbiology
April 2000
Characterization of a new set of mutants deficient in fermentation-induced loss of stre...
International Journal of Food Microbiology
April 2000
Identification of genes responsible for improved cryoresistance in fermenting yeast cells
International Journal of Food Microbiology
April 2000
Analysis and modification of trehalose 6-phosphate levels in the yeast Saccharomyces ce...
Biochemical Journal
January 2000
Deletion ofSFI1, a novel suppressor of partial Ras-cAMP pathway deficiency in the yeast...
Yeast
August 1999
A mutation in Saccharomyces cerevisiae adenylate cyclase, Cyr1K1876M, specifically affe...
Molecular Microbiology
July 1999
A Saccharomyces cerevisiae G-protein coupled receptor, Gpr1, is specifically required f...
Molecular Microbiology
June 1999
The PDE1-encoded Low-Affinity Phosphodiesterase in the Yeast Saccharomyces cerevisiae H...
Molecular Biology of the Cell
January 1999
Molecular cloning of the neutral trehalase gene from Kluyveromyces lactis and the disti...
Archives of Microbiology
March 1997
Regulation of genes encoding subunits of the trehalose synthase complex inSaccharomyces...
MGG Molecular & General Genetics
September 1996
Regulation of genes encoding subunits of the trehalose synthase complex in
MGG Molecular & General Genetics
January 1996
The byp1-3 allele of the Saccharomyces cerevisiae GGS1/TPS1 gene and its multi-copy sup...
Current Genetics
October 1994
A Fos-Jun element in the first intron of an α2u-globulin gene
Molecular and Cellular Biochemistry
August 1993
Multiple binding sites for nuclear factors in the 5′-upstream region of two α2u-globuli...
The Journal of Steroid Biochemistry and Molecular Biology
May 1993
Molecular cloning of a gene involved in glucose sensing in the yeast Saccharomyces cere...
Molecular Microbiology
May 1993
Interaction of the 90-kDa heat shock protein with native and in vitro translated androg...
Molecular and Cellular Endocrinology
October 1992
Tissue-Specific Expression and Androgen Regulation of Different Genes Encoding Rat Pros...
Molecular Endocrinology
April 1990
Binding of androgen-receptor complexes to α2u-globulin genes and to the long terminal r...
Molecular and Cellular Endocrinology
July 1989
Kallikrein-related protease in the rat ventral prostate: cDNA cloning and androgen regu...
Molecular and Cellular Endocrinology
April 1989
Glucocorticoid receptor binding to defined regions of α2 u-globulin genes
Biochemical and Biophysical Research Communications
December 1987
Comparison of the 5' upstream putative regulatory sequences of three members of the alp...
European Journal of Biochemistry
June 1987
New Selection Marker for Plant Transformation