All Stories

  1. Finnish-Enriched SLC26A7 Variant in Congenital Hypothyroidism: Clinical Spectrum, Thyroid Histopathology, and Expression Analysis

    Article • Thyroid, January 2026, SAGE Publications

    Dr päivi miettinen

  2. Puberty‐Promoting Treatment and Psychosocial Well‐Being in Boys With Constitutional Delay of Puberty: A Randomized Controlled Trial

    Article • Clinical Endocrinology, October 2025, Wiley

    Dr päivi miettinen

  3. Impact of Aromatase Inhibition on Bone Mineral Density and Structure: A Randomized Controlled Trial in Boys With Delayed Puberty

    Article • European Journal of Endocrinology, August 2025, Oxford University Press (OUP)

    Dr päivi miettinen

  4. RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function

    Article • Diabetologia, May 2024, Springer Science + Business Media

    Dr päivi miettinen

  5. Prenatal, newborn and childhood factors and the timing of puberty in boys and girls

    Article • Pediatric Research, April 2024, Springer Science + Business Media

    Dr päivi miettinen

  6. During an 18‐month course of automated insulin delivery treatment, children aged 2 to 6 years achieve and maintain a higher time in tight range

    Article • Diabetes Obesity and Metabolism, March 2024, Wiley

    Dr päivi miettinen

  7. Health-related quality of life and self-reported health status in adolescents with chronic health conditions before transfer of care to adult health care: an international cohort study

    Article • BMC Pediatrics, March 2024, Springer Science + Business Media

    Dr päivi miettinen

  8. Central precocious puberty in boys: secular trend and clinical features

    Article • European Journal of Endocrinology, March 2024, Oxford University Press (OUP)

    Dr päivi miettinen

  9. Mechanisms of thyrotropin receptor–mediated phenotype variability deciphered by gene mutations and M453T-knockin model

    Article • JCI Insight, January 2024, American Society for Clinical Investigation

    Dr päivi miettinen, Saila Laakso

  10. Congenital hypogonadotropic hypogonadism in a patient with a de novoPOGZmutation

    Article • European Journal of Endocrinology, August 2023, Oxford University Press (OUP)

    Dr päivi miettinen

  11. Residual insulin secretion in individuals with type 1 diabetes in Finland: longitudinal and cross-sectional analyses

    Article • The Lancet Diabetes & Endocrinology, July 2023, Elsevier

    Dr päivi miettinen

  12. Pancreatic imaging in MEN1—comparison of conventional and somatostatin receptor positron emission tomography/computed tomography imaging in real-life setting

    Article • European Journal of Endocrinology, March 2023, Oxford University Press (OUP)

    Dr päivi miettinen

  13. Disease control and psychiatric comorbidity among adolescents with chronic medical conditions: a single-centre retrospective study

    Article • BMJ Paediatrics Open, February 2023, BMJ

    Mira Kallio, Dr päivi miettinen

  14. MiniMed 780G™ in 2- to 6-Year-Old Children: Safety and Clinical Outcomes After the First 12 Weeks

    Article • Diabetes Technology & Therapeutics, February 2023, Mary Ann Liebert Inc

    Dr päivi miettinen, Saila Laakso

  15. Health-related quality of life in boys with constitutional delay of growth and puberty

    Article • Frontiers in Endocrinology, November 2022, Frontiers

    Dr päivi miettinen

  16. Identification of monogenic variants in more than ten per cent of children without type 1 diabetes-related autoantibodies at diagnosis in the Finnish Pediatric Diabetes Register

    Article • Diabetologia, November 2022, Springer Science + Business Media

    Dr päivi miettinen

  17. Presentation and diagnosis of childhood-onset combined pituitary hormone deficiency: A single center experience from over 30 years

    Article • EClinicalMedicine, September 2022, Elsevier

    Dr päivi miettinen

  18. Timing of puberty and school performance: A population-based study

    Article • Frontiers in Endocrinology, August 2022, Frontiers

    Dr päivi miettinen

  19. Circulating Liver-enriched Antimicrobial Peptide-2 Decreases During Male Puberty

    Article • Journal of the Endocrine Society, February 2022, Endocrine Society

    Dr päivi miettinen

  20. The effect of COVID-19 lockdown on the glycemic control of children with type 1 diabetes

    Article • BMC Pediatrics, January 2022, Springer Science + Business Media

    Dr päivi miettinen

  21. A multigenerational study on phenotypic consequences of the most common causal variant of HNF1A-MODY

    Article • Diabetologia, December 2021, Springer Science + Business Media

    Dr päivi miettinen

  22. Gut microbiota develop towards an adult profile in a sex-specific manner during puberty

    Article • Scientific Reports, December 2021, Springer Science + Business Media

    Dr päivi miettinen

  23. The aetiology of extreme tall stature in a screened Finnish paediatric population

    Article • EClinicalMedicine, December 2021, Elsevier

    Dr päivi miettinen

  24. Cytosolic phosphoenolpyruvate carboxykinase deficiency: Expanding the clinical phenotype and novel laboratory findings

    Article • Journal of Inherited Metabolic Disease, November 2021, Wiley

    Dr päivi miettinen

  25. Serum testosterone and oestradiol predict the growth response during puberty promoting treatment

    Article • Clinical Endocrinology, October 2021, Wiley

    Dr päivi miettinen

  26. Onset and progression of puberty in Klinefelter syndrome

    Article • Clinical Endocrinology, September 2021, Wiley

    Dr päivi miettinen

  27. Bridge study protocol: an international, observational cohort study on the transition of healthcare for adolescents with chronic conditions

    Article • BMJ Open, June 2021, BMJ

    Dr päivi miettinen

  28. First year on commercial hybrid closed‐loop system—experience on 111 children and adolescents with type 1 diabetes

    Article • Pediatric Diabetes, May 2021, Wiley

    Dr päivi miettinen

  29. New-onset type 1 diabetes in Finnish children during the COVID-19 pandemic

    Article • Archives of Disease in Childhood, May 2021, BMJ

    Dr päivi miettinen

  30. Circulating miR-30b levels increase during male puberty

    Article • European Journal of Endocrinology, May 2021, Oxford University Press (OUP)

    Dr päivi miettinen

  31. Impact of SARS-CoV-2 Pandemic and Strategies for Resumption of Activities During the Second Wave of the Pandemic: A Report From Eight Paediatric Hospitals From the ECHO Network

    Article • Frontiers in Public Health, April 2021, Frontiers

    Dr päivi miettinen

  32. Bone structure assessed with pQCT in prepubertal males with delayed puberty or congenital hypogonadotropic hypogonadism

    Article • Clinical Endocrinology, March 2021, Wiley

    Dr päivi miettinen

  33. Motivational Interviewing and Glycemic Control in Adolescents With Poorly Controlled Type 1 Diabetes: A Randomized Controlled Pilot Trial

    Article • Frontiers in Endocrinology, March 2021, Frontiers

    Dr päivi miettinen

  34. Familial central precocious puberty: two novel MKRN3 mutations

    Article • Pediatric Research, November 2020, Springer Science + Business Media

    Dr päivi miettinen

  35. Etiology of severe short stature below −3 SDS in a screened Finnish population

    Article • European Journal of Endocrinology, November 2020, Oxford University Press (OUP)

    Dr päivi miettinen

  36. Androgen deprivation and SARS-CoV-2 in men with prostate cancer

    Article • Annals of Oncology, October 2020, Elsevier

    Dr päivi miettinen

  37. Loss-of-Function Variants in TBC1D32 Underlie Syndromic Hypopituitarism

    Article • The Journal of Clinical Endocrinology & Metabolism, February 2020, Endocrine Society

    Dr päivi miettinen

  38. Anti-Müllerian hormone and letrozole levels in boys with constitutional delay of growth and puberty treated with letrozole or testosterone

    Article • Human Reproduction, January 2020, Oxford University Press (OUP)

    Dr päivi miettinen

  39. Constitutional delay of puberty versus congenital hypogonadotropic hypogonadism: Genetics, management and updates

    Article • Best Practice & Research Clinical Endocrinology & Metabolism, June 2019, Elsevier

    Dr päivi miettinen

  40. Treatment of gonadotropin deficiency during the first year of life: long-term observation and outcome in five boys

    Article • Human Reproduction, April 2019, Oxford University Press (OUP)

    Dr päivi miettinen

  41. Letrozole versus testosterone for promotion of endogenous puberty in boys with constitutional delay of growth and puberty: a randomised controlled phase 3 trial

    Article • The Lancet Child & Adolescent Health, February 2019, Elsevier

    Dr päivi miettinen

  42. Recombinant Human FSH Treatment Outcomes in Five Boys With Severe Congenital Hypogonadotropic Hypogonadism

    Article • Journal of the Endocrine Society, October 2018, Endocrine Society

    Dr päivi miettinen

  43. The Role of KCNQ1 Mutations and Maternal Beta Blocker Use During Pregnancy in the Growth of Children With Long QT Syndrome

    Article • Frontiers in Endocrinology, April 2018, Frontiers

    Dr päivi miettinen

  44. Disorders of sex development: timing of diagnosis and management in a single large tertiary center

    Article • Endocrine Connections, March 2018, Bioscientifica

    Prof Taneli Raivio, Dr päivi miettinen

  45. GnRH receptor gene mutations in adolescents and young adults presenting with signs of partial gonadotropin deficiency

    Article • PLOS One, November 2017, PLOS

    Dr päivi miettinen

  46. Heterozygous RFX6 protein truncating variants are associated with MODY with reduced penetrance

    Article • Nature Communications, October 2017, Nature

    Dr päivi miettinen

  47. Precocious Puberty or Premature Thelarche: Analysis of a Large Patient Series in a Single Tertiary Center with Special Emphasis on 6- to 8-Year-Old Girls

    Article • Frontiers in Endocrinology, August 2017, Frontiers

    Prof Taneli Raivio, Dr päivi miettinen

  48. Biliary Anomalies in Patients With HNF1B Diabetes

    Article • The Journal of Clinical Endocrinology & Metabolism, March 2017, Endocrine Society

    Dr päivi miettinen

  49. Congenital hypogonadotropic hypogonadism, functional hypogonadotropism or constitutional delay of growth and puberty? An analysis of a large patient series from a single tertiary center

    Article • Human Reproduction, December 2016, Oxford University Press (OUP)

    Prof Taneli Raivio, Dr päivi miettinen

  50. Detection of Novel Gene Variants Associated with Congenital Hypothyroidism in a Finnish Patient Cohort

    Article • Thyroid, September 2016, Mary Ann Liebert Inc

    Dr päivi miettinen

  51. Fundus Photography as a Screening Method for Diabetic Retinopathy in Children With Type 1 Diabetes: Outcome of the Initial Photography

    Article • American Journal of Ophthalmology, September 2016, Elsevier

    Dr päivi miettinen

  52. Clinical, Genetic, and Biochemical Characteristics of Early-Onset Diabetes in the Finnish Population

    Article • The Journal of Clinical Endocrinology & Metabolism, August 2016, Endocrine Society

    Dr päivi miettinen

  53. Circulating makorin ring finger protein 3 levels decline in boys before the clinical onset of puberty

    Article • European Journal of Endocrinology, March 2016, Bioscientifica

    Prof Taneli Raivio, Dr päivi miettinen, Dr Matti Hero

  54. Childhood growth in boys with congenital hypogonadotropic hypogonadism

    Article • Pediatric Research, December 2015, Nature

    Prof Taneli Raivio, Dr päivi miettinen

  55. Early-Onset Diabetic E1-DN Mice Develop Albuminuria and Glomerular Injury Typical of Diabetic Nephropathy

    Article • BioMed Research International, January 2015, Hindawi Publishing Corporation

    Dr päivi miettinen, Sanna Lehtonen

  56. EGFR Signaling Promotes β-Cell Proliferation and Survivin Expression during Pregnancy

    Article • PLOS One, April 2014, PLOS

    Dr päivi miettinen

  57. In vivo activation of the PI3K–Akt pathway in mouse beta cells by the EGFR mutation L858R protects against diabetes

    Article • Diabetologia, February 2014, Springer Science + Business Media

    Dr päivi miettinen

  58. Use of Electronic Health Records for Automated Screening of Growth Disorders in Primary Care

    Article • JAMA, September 2013, American Medical Association (AMA)

    Dr päivi miettinen

  59. Gender Identity and Gender Role Orientation in Female Assigned Patients with Disorders of Sex Development

    Article • The Journal of Urology, November 2012, Elsevier

    Dr päivi miettinen

  60. Prevalence and characteristics of diabetes among Somali children and adolescents living in Helsinki, Finland

    Article • Pediatric Diabetes, May 2011, Wiley

    Dr päivi miettinen

  61. Sexual Function and Attitudes Toward Surgery After Feminizing Genitoplasty

    Article • The Journal of Urology, May 2011, Elsevier

    Dr päivi miettinen

  62. Epidermal growth factor (EGF)-receptor signalling is needed for murine beta cell mass expansion in response to high-fat diet and pregnancy but not after pancreatic duct ligation

    Article • Diabetologia, April 2011, Springer Science + Business Media

    Dr päivi miettinen

  63. Sexual Function and Attitudes towards Surgery After Feminizing Genitoplasty

    Article • Journal of Pediatric Urology, April 2010, Elsevier

    Dr päivi miettinen

  64. Transcription factor AP-1 promotes growth and radioresistance in prostate cancer cells

    Article • International Journal of Oncology, September 2009, Spandidos Publications

    Dr päivi miettinen

  65. EGF-receptor regulates salivary gland branching morphogenesis by supporting proliferation and maturation of epithelial cells and survival of mesenchymal cells

    Article • Differentiation, March 2009, Elsevier

    Dr päivi miettinen

  66. EGF receptor in pancreatic β-cell mass regulation

    Article • Biochemical Society Transactions, June 2008, Portland Press Ltd.

    Dr päivi miettinen

  67. ERBB receptors in developing, dysplastic and malignant oral epithelia

    Article • Oral Oncology, March 2008, Elsevier

    Dr päivi miettinen

  68. Hydrocortisone and Indomethacin Negatively Modulate EGF-R Signaling in Human Fetal Intestine

    Article • Pediatric Research, November 2007, Nature

    Dr päivi miettinen

  69. EGF-R regulates MMP function in fibroblasts through MAPK and AP-1 pathways

    Article • Journal of Cellular Physiology, March 2007, Wiley

    Dr päivi miettinen

  70. Downregulation of EGF Receptor Signaling in Pancreatic Islets Causes Diabetes Due to Impaired Postnatal  -Cell Growth

    Article • Diabetes, November 2006, American Diabetes Association

    Dr päivi miettinen

  71. Effects of epidermal growth factor receptor deficiency and 2,3,7,8-tetrachlorodibenzo-p-dioxin on fetal development in mice

    Article • Toxicology Letters, May 2004, Elsevier

    Dr päivi miettinen

  72. Novel splice site CACNA1A mutation causing episodic ataxia type 2

    Article • Neurogenetics, February 2004, Springer Science + Business Media

    Dr päivi miettinen

  73. Different Mechanisms of Syndecan-1 Activation through a Fibroblast-growth-factor-inducible Response Element (FiRE) in Mucosal and Cutaneous Wounds

    Article • Journal of Dental Research, May 2003, SAGE Publications

    Dr päivi miettinen

  74. ErbB Signaling Regulates Lineage Determination of Developing Pancreatic Islet Cells in Embryonic Organ Culture

    Article • Endocrinology, November 2002, Endocrine Society

    Dr päivi miettinen

  75. Abnormal astrocyte development and neuronal death in mice lacking the epidermal growth factor receptor

    Article • Journal of Neuroscience Research, September 1998, Wiley

    Dr päivi miettinen

  76. Uterine and Vaginal Organ Growth Requires Epidermal Growth Factor Receptor Signaling from Stroma1

    Article • Endocrinology, March 1998, Endocrine Society

    Dr päivi miettinen

  77. Impaired Lung Branching Morphogenesis in the Absence of Functional EGF Receptor

    Article • Developmental Biology, June 1997, Elsevier

    Dr päivi miettinen

  78. A WD-domain protein that is associated with and phosphorylated by the type II TGF-β receptor

    Article • Nature, October 1995, Nature

    Dr päivi miettinen

  79. Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor

    Article • Nature, July 1995, Nature

    Dr päivi miettinen

  80. Transforming Growth Factor-α and Epidermal Growth Factor Expression in Human Fetal Gastrointestinal Tract

    Article • Pediatric Research, May 1993, Nature

    Dr päivi miettinen

  81. EGF- and TGF-α-Like Peptides in Human Fetal Gut

    Article • Pediatric Research, July 1989, Nature

    Dr päivi miettinen