All Stories

  1. Unsupervised Flow Cytometry Reveals a Constant Shift Towards Activated CD4 + T Cell Subsets in APECED

    Article • Scandinavian Journal of Immunology, June 2026, Wiley

    Saila Laakso

  2. Intravenous Glucose Tolerance Tests in Predicting Diabetes Onset in APECED: A Retrospective Cohort Study

    Article • Journal of the Endocrine Society, November 2025, Endocrine Society

    Saila Laakso

  3. Increased type 1 inflammation in gynecologic cervicovaginal samples in patients with APS-1

    Article • Journal of Allergy and Clinical Immunology, June 2024, Elsevier

    Mikko I. Mäyränpää, Saila Laakso

  4. Dysregulated germinal center reaction with expanded T follicular helper cells in autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy lymph nodes

    Article • Journal of Allergy and Clinical Immunology, May 2024, Elsevier

    Mikko I. Mäyränpää, Saila Laakso

  5. Progressive Impairment of Prepubertal Growth in Children With APECED

    Article • The Journal of Clinical Endocrinology & Metabolism, April 2024, Endocrine Society

    Saila Laakso

  6. A novel link between chronic inflammation and humanin regulation in children

    Article • Frontiers in Endocrinology, January 2024, Frontiers

    Saila Laakso

  7. Mechanisms of thyrotropin receptor–mediated phenotype variability deciphered by gene mutations and M453T-knockin model

    Article • JCI Insight, January 2024, American Society for Clinical Investigation

    Dr päivi miettinen, Saila Laakso

  8. Epidemiology and Causes of Primary Adrenal Insufficiency in Children: A Population-Based Study

    Article • The Journal of Clinical Endocrinology & Metabolism, May 2023, Endocrine Society

    Saila Laakso

  9. Bone Tissue Evaluation Indicates Abnormal Mineralization in Patients with Autoimmune Polyendocrine Syndrome Type I: Report on Three Cases

    Article • Calcified Tissue International, March 2023, Springer Science + Business Media

    Saila Laakso

  10. Pubertal development and hypogonadism in males with autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy: a retrospective study

    Article • European Journal of Endocrinology, March 2023, Oxford University Press (OUP)

    Mikko I. Mäyränpää, Saila Laakso

  11. MiniMed 780G™ in 2- to 6-Year-Old Children: Safety and Clinical Outcomes After the First 12 Weeks

    Article • Diabetes Technology & Therapeutics, February 2023, Mary Ann Liebert Inc

    Dr päivi miettinen, Saila Laakso

  12. Recurrent Hypokalemia and Adrenal Steroids in Patients With APECED

    Article • Frontiers in Endocrinology, June 2022, Frontiers

    Saila Laakso

  13. Endocrine Disorders and Genital Infections Impair Gynecological Health in APECED (APS-1)

    Article • Frontiers in Endocrinology, November 2021, Frontiers

    Saila Laakso

  14. Long-term Outcome of Kidney Transplantation in 6 Patients With Autoimmune Polyendocrinopathy-candidiasis-ectodermal Dystrophy

    Article • Transplantation, November 2021, Wolters Kluwer Health

    Saila Laakso

  15. Infections and demanding endocrine care contribute to increased mortality in patients with APECED

    Article • European Journal of Endocrinology, November 2021, Oxford University Press (OUP)

    Saila Laakso

  16. Patients with autoimmune polyendocrine syndrome type 1 have an increased susceptibility to severe herpesvirus infections

    Article • Clinical Immunology, October 2021, Elsevier

    Saila Laakso

  17. Pregnancy Outcome in Women With APECED (APS-1): A Multicenter Study on 43 Females With 83 Pregnancies

    Article • The Journal of Clinical Endocrinology & Metabolism, September 2021, Endocrine Society

    Saila Laakso

  18. Fecal Bacteria Implicated in Biofilm Production Are Enriched and Associate to Gastrointestinal Symptoms in Patients With APECED – A Pilot Study

    Article • Frontiers in Immunology, July 2021, Frontiers

    Saila Laakso

  19. Pubertal development and premature ovarian insufficiency in patients with APECED

    Article • European Journal of Endocrinology, November 2020, Oxford University Press (OUP)

    Saila Laakso

  20. Impaired Bone Health in Children With Biliary Atresia

    Article • Journal of Pediatric Gastroenterology and Nutrition, August 2020, Wiley

    Saila Laakso

  21. Patients With APECED Have Increased Early Mortality Due to Endocrine Causes, Malignancies and infections

    Article • The Journal of Clinical Endocrinology & Metabolism, March 2020, Endocrine Society

    Saila Laakso

  22. Severe Phenotype of APECED (APS1) Increases Risk for Structural Bone Alterations

    Article • Frontiers in Endocrinology, March 2020, Frontiers

    Saila Laakso

  23. The autoimmune targets in IPEX are dominated by gut epithelial proteins

    Article • Journal of Allergy and Clinical Immunology, July 2019, Elsevier

    Saila Laakso

  24. Oral Tongue Malignancies in Autoimmune Polyendocrine Syndrome Type 1

    Article • Frontiers in Endocrinology, August 2018, Frontiers

    Saila Laakso

  25. Testicular function and bone in young men with severe obesity

    Article • Hormone Research in Paediatrics, January 2018, Karger Publishers

    Saila Laakso

  26. Diverse Autoantibody Reactivity in Cartilage-Hair Hypoplasia

    Article • Journal of Clinical Immunology, June 2017, Springer Science + Business Media

    Saila Laakso

  27. Increased bone resorption markers in young patients with inflammatory bowel disease

    Article • Bone Abstracts, April 2016, Bioscientifica

    Saila Laakso

  28. Premature Adrenarche - A Common Condition with Variable Presentation

    Article • Hormone Research in Paediatrics, February 2015, Karger Publishers

    Saila Laakso, M.D., PH.D. Pauliina Utriainen

  29. Compromised Peak Bone Mass in Patients with Inflammatory Bowel Disease–A Prospective Study

    Article • The Journal of Pediatrics, June 2014, Elsevier

    Saila Laakso

  30. Serum androgen bioactivity is low in children with premature adrenarche

    Article • Pediatric Research, February 2014, Nature

    Saila Laakso, M.D., PH.D. Pauliina Utriainen

  31. Polymorphisms of POR, SULT2A1 and HSD11B1 in children with premature adrenarche

    Article • Metabolism, September 2012, Elsevier

    Saila Laakso, M.D., PH.D. Pauliina Utriainen

  32. Impaired Bone Health in Inflammatory Bowel Disease: A Case–Control Study in 80 Pediatric Patients

    Article • Calcified Tissue International, June 2012, Springer Science + Business Media

    Saila Laakso

  33. Polymorphism Pro12Ala of PPARG in Prepubertal Children with Premature Adrenarche and Its Association with Growth in Healthy Children

    Article • Hormone Research in Paediatrics, January 2010, Karger Publishers

    Saila Laakso, M.D., PH.D. Pauliina Utriainen

  34. Genetic variation of FTO and TCF7L2 in premature adrenarche

    Article • Metabolism, September 2009, Elsevier

    Saila Laakso, M.D., PH.D. Pauliina Utriainen

  35. LRP5in premature adrenarche and in metabolic characteristics of prepubertal children

    Article • Clinical Endocrinology, May 2009, Wiley

    Saila Laakso, M.D., PH.D. Pauliina Utriainen

  36. Androgen Receptor Gene CAG Repeat Polymorphism and X-Chromosome Inactivation in Children with Premature Adrenarche

    Article • The Journal of Clinical Endocrinology & Metabolism, April 2008, Endocrine Society

    Saila Laakso, M.D., PH.D. Pauliina Utriainen

  37. ACTH Receptor Promoter Polymorphism Associates With Severity of Premature Adrenarche and Modulates Hypothalamo-Pituitary-Adrenal Axis in Children

    Article • Pediatric Research, April 2008, Nature

    Saila Laakso, M.D., PH.D. Pauliina Utriainen