All Stories

  1. Disorders of sex development: timing of diagnosis and management in a single large tertiary center

    Article • Endocrine Connections, March 2018, Bioscientifica

    Prof Taneli Raivio, Dr päivi miettinen

  2. Two missense mutations in KCNQ1 cause pituitary hormone deficiency and maternally inherited gingival fibromatosis

    Article • Nature Communications, November 2017, Nature

    Prof Taneli Raivio

  3. Modeling development of human embryonic stem cells to gonadal-like cells

    Article • The Journal of Clinical Endocrinology & Metabolism, August 2017, Endocrine Society

    Prof Taneli Raivio, Kirsi Sepponen

  4. Precocious Puberty or Premature Thelarche: Analysis of a Large Patient Series in a Single Tertiary Center with Special Emphasis on 6- to 8-Year-Old Girls

    Article • Frontiers in Endocrinology, August 2017, Frontiers

    Prof Taneli Raivio, Dr päivi miettinen

  5. Congenital hypogonadotropic hypogonadism, functional hypogonadotropism or constitutional delay of growth and puberty? An analysis of a large patient series from a single tertiary center

    Article • Human Reproduction, December 2016, Oxford University Press (OUP)

    Prof Taneli Raivio, Dr päivi miettinen

  6. Complete androgen insensitivity syndrome caused by a deep intronic pseudoexon-activating mutation in the androgen receptor gene

    Article • Scientific Reports, September 2016, Nature

    Prof Taneli Raivio

  7. Development of Gonadotropin-Releasing Hormone-Secreting Neurons from Human Pluripotent Stem Cells

    Article • Stem Cell Reports, August 2016, Elsevier

    Prof Taneli Raivio

  8. Circulating makorin ring finger protein 3 levels decline in boys before the clinical onset of puberty

    Article • European Journal of Endocrinology, March 2016, Bioscientifica

    Prof Taneli Raivio, Dr päivi miettinen, Dr Matti Hero

  9. Circulating makorin ring-finger protein-3 (MKRN3) levels in healthy men and in men with hypogonadotropic hypogonadism

    Article • Clinical Endocrinology, March 2016, Wiley

    Prof Taneli Raivio

  10. MANAGEMENT OF ENDOCRINE DISEASE: Reversible hypogonadotropic hypogonadism: Table 1

    Article • European Journal of Endocrinology, January 2016, Bioscientifica

    Prof Taneli Raivio, Dr Andrew A Dwyer

  11. Childhood growth in boys with congenital hypogonadotropic hypogonadism

    Article • Pediatric Research, December 2015, Nature

    Prof Taneli Raivio, Dr päivi miettinen

  12. A missense mutation in MKRN3 in a Danish girl with central precocious puberty and her brother with early puberty

    Article • Pediatric Research, September 2015, Nature

    Prof Taneli Raivio

  13. Letter to the Editor: Comment On The Treatment Of Adolescent Boys With Hypogonadotropic Hypogonadism By Gong C., et al

    Article • The Journal of Clinical Endocrinology & Metabolism, September 2015, Endocrine Society

    Prof Taneli Raivio

  14. Circulating makorin ring-finger protein-3 (MKRN3) levels in healthy men and in men with hypogonadotropic hypogonadism

    Article • Clinical Endocrinology, August 2015, Wiley

    Prof Taneli Raivio

  15. Expert consensus document: European Consensus Statement on congenital hypogonadotropic hypogonadism—pathogenesis, diagnosis and treatment

    Article • Nature Reviews Endocrinology, July 2015, Nature

    Prof Taneli Raivio, Dr Andrew A Dwyer

  16. Gonadotropin-releasing hormone receptor mutations in ageing men

    Article • Clinical Endocrinology, July 2015, Wiley

    Prof Taneli Raivio

  17. Combined negative effect of donor age and time in culture on the reprogramming efficiency into induced pluripotent stem cells

    Article • Stem Cell Research, July 2015, Elsevier

    Prof Taneli Raivio

  18. Health-related quality of life in male patients with congenital hypogonadotropic hypogonadism

    Article • Clinical Endocrinology, January 2015, Wiley

    Prof Taneli Raivio, Dr Matti Hero

  19. Comment on reversal of hypogonadotropic hypogonadism in a Chinese cohort

    Article • Asian Journal of Andrology, January 2015, Medknow

    Prof Taneli Raivio, Dr Andrew A Dwyer

  20. Gonadotrophin replacement for induction of fertility in hypogonadal men

    Article • Best Practice & Research Clinical Endocrinology & Metabolism, January 2015, Elsevier

    Prof Taneli Raivio, Dr Andrew A Dwyer

  21. Neural Progenitor Cells Derived from Human Embryonic Stem Cells as an Origin of Dopaminergic Neurons

    Article • Stem Cells International, January 2015, Hindawi Publishing Corporation

    Prof Taneli Raivio

  22. Congenital hypogonadotropic hypogonadism with split hand/foot malformation: a clinical entity with a high frequency of FGFR1 mutations

    Article • Genetics in Medicine, November 2014, Nature

    Prof Taneli Raivio, Dr Andrew A Dwyer

  23. Neural crest cells: From developmental biology to clinical interventions

    Article • Birth Defects Research Part C Embryo Today Reviews, September 2014, Wiley

    Prof Taneli Raivio

  24. Genetics of congenital hypogonadotropic hypogonadism in Denmark

    Article • European Journal of Medical Genetics, July 2014, Elsevier

    Prof Taneli Raivio

  25. Childhood growth of females with Kallmann syndrome andFGFR1mutations

    Article • Clinical Endocrinology, June 2014, Wiley

    Dr Matti Hero, Prof Taneli Raivio, Dr Matti Hero

  26. De novo SOX10 nonsense mutation in a patient with Kallmann syndrome and hearing loss

    Article • Pediatric Research, April 2014, Springer Science + Business Media

    Professor Vallo Tillmann, Prof Taneli Raivio

  27. High frequency of FGFR1 mutations in patients with congenital hypogonadotropic hypogonadism and split hand/foot malformation

    Article • Endocrine Abstracts, April 2014, Bioscientifica

    Prof Taneli Raivio

  28. Notch signaling regulates the differentiation of neural crest from human pluripotent stem cells

    Article • Journal of Cell Science, February 2014, The Company of Biologists

    Prof Taneli Raivio

  29. Mutation screening of SEMA3A and SEMA7A in patients with congenital hypogonadotropic hypogonadism

    Article • Pediatric Research, February 2014, Nature

    Prof Taneli Raivio

  30. Serum FGF21 increases with hepatic fat accumulation in pediatric onset intestinal failure

    Article • Journal of Hepatology, January 2014, Elsevier

    Prof Taneli Raivio

  31. Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 Are Identified in Individuals with Congenital Hypogonadotropic Hypogonadism

    Article • The American Journal of Human Genetics, May 2013, Elsevier

    Richard Quinton, Prof Taneli Raivio, Dr Andrew A Dwyer

  32. Hereditary myopathy with early respiratory failure: occurrence in various populations

    Article • Journal of Neurology Neurosurgery & Psychiatry, April 2013, BMJ

    Prof Taneli Raivio, Giorgio Tasca

  33. PROKR2 mutations in autosomal recessive Kallmann syndrome

    Article • Fertility and Sterility, March 2013, Elsevier

    Prof Taneli Raivio

  34. A homozygous R262Q mutation in the gonadotropin-releasing hormone receptor presenting as reversal of hypogonadotropic hypogonadism and late-onset hypogonadism

    Article • Clinical Endocrinology, January 2013, Wiley

    Prof Taneli Raivio

  35. CHARGE syndrome and Kallmann syndrome: are the two genetically related?

    Article • Expert Review of Endocrinology & Metabolism, November 2012, Informa Healthcare

    Prof Taneli Raivio

  36. Reversible Congenital Hypogonadotropic Hypogonadism in Patients with CHD7, FGFR1 or GNRHR Mutations

    Article • PLoS ONE, June 2012, PLOS

    Prof Taneli Raivio

  37. Cholesterol Metabolism Altered and FGF21 Levels High After Pediatric Liver Transplantation Despite Normal Serum Lipids

    Article • American Journal of Transplantation, June 2012, Wiley

    Prof Taneli Raivio

  38. Circulating antimüllerian hormone levels in boys decline during early puberty and correlate with inhibin B

    Article • Fertility and Sterility, May 2012, Elsevier

    Prof Taneli Raivio, Dr Matti Hero

  39. Genetic Overlap in Kallmann Syndrome, Combined Pituitary Hormone Deficiency, and Septo-Optic Dysplasia

    Article • The Journal of Clinical Endocrinology & Metabolism, April 2012, Endocrine Society

    Richard Quinton, Prof Taneli Raivio, Dr Andrew A Dwyer

  40. Bone mineral density, body composition and bone turnover in patients with congenital hypogonadotropic hypogonadism

    Article • International Journal of Andrology, January 2012, Wiley

    Prof Taneli Raivio

  41. Circulating Anti-Müllerian Hormone Levels in Adult Men Are under a Strong Genetic Influence

    Article • The Journal of Clinical Endocrinology & Metabolism, January 2012, Endocrine Society

    Prof Taneli Raivio

  42. Genetic Overlap between Holoprosencephaly and Kallmann Syndrome

    Article • Molecular Syndromology, January 2012, Karger Publishers

    Prof Taneli Raivio

  43. Decrease in circulating fibroblast growth factor 21 after an oral fat load is related to postprandial triglyceride-rich lipoproteins and liver fat

    Article • December 2011, Bioscientifica

    Prof Taneli Raivio

  44. Isolated cryptorchidism: No evidence for involvement of genes underlying isolated hypogonadotropic hypogonadism

    Article • Molecular and Cellular Endocrinology, July 2011, Elsevier

    Prof Taneli Raivio

  45. Serum FGF21 in boys with idiopathic short stature: relationship to lipid profile, onset of puberty and growth*

    Article • Clinical Endocrinology, June 2011, Wiley

    Prof Taneli Raivio, Dr Matti Hero

  46. The role of gene defects underlying isolated hypogonadotropic hypogonadism in patients with constitutional delay of growth and puberty

    Article • Fertility and Sterility, June 2011, Elsevier

    Prof Taneli Raivio

  47. Gain-of-Function Mutation in FGFR1 in Human GnRH Deficiency

    Article • June 2011, Endocrine Society

    Prof Taneli Raivio

  48. Intra-articular corticoid injection induces circulating glucocorticoid bioactivity and systemic immune activation in juvenile idiopathic arthritis

    Article • Scandinavian Journal of Rheumatology, May 2011, Informa Healthcare

    Prof Taneli Raivio

  49. Serum angiopoietin-like 4 protein levels and expression in adipose tissue are inversely correlated with obesity in monozygotic twins

    Article • Journal of Lipid Research, May 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Taneli Raivio

  50. Exome Sequencing Identifies Mitochondrial Alanyl-tRNA Synthetase Mutations in Infantile Mitochondrial Cardiomyopathy

    Article • The American Journal of Human Genetics, May 2011, Elsevier

    Prof Taneli Raivio

  51. Liver Fat But Not Other Adiposity Measures Influence Circulating FGF21 Levels in Healthy Young Adult Twins

    Article • The Journal of Clinical Endocrinology & Metabolism, February 2011, Endocrine Society

    Prof Taneli Raivio

  52. Incidence, Phenotypic Features and Molecular Genetics of Kallmann Syndrome in Finland

    Article • Orphanet Journal of Rare Diseases, January 2011, Springer Science + Business Media

    Prof Taneli Raivio

  53. LIN28B, LIN28A, KISS1, and KISS1R in idiopathic central precocious puberty

    Article • BMC Research Notes, January 2011, Springer Science + Business Media

    Prof Taneli Raivio

  54. Comparison of solution-based exome capture methods for next generation sequencing

    Article • Genome Biology, January 2011, Springer Science + Business Media

    Prof Taneli Raivio, Samuli Eldfors

  55. LIN28Bin Constitutional Delay of Growth and Puberty

    Article • The Journal of Clinical Endocrinology & Metabolism, June 2010, Endocrine Society

    Prof Taneli Raivio

  56. Idiopathic hypogonadotropic hypogonadism in a mother and her monozygotic twins born after a single embryo transfer

    Article • Fertility and Sterility, April 2010, Elsevier

    Prof Taneli Raivio

  57. Glucocorticoid bioactivity does not predict response to steroid therapy in severe pediatric ulcerative colitis

    Article • Inflammatory Bowel Diseases, March 2010, Wolters Kluwer Health

    Prof Taneli Raivio

  58. Complex Genetics in Idiopathic Hypogonadotropic Hypogonadism

    Article • January 2010, Karger Publishers

    Prof Taneli Raivio

  59. High-sensitivity C-reactive protein in paediatric inflammatory bowel disease

    Article • World Journal of Gastroenterology, January 2010, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Prof Taneli Raivio

  60. Serum glucocorticoids and adiponectin associate with insulin resistance in children born small for gestational age

    Article • European Journal of Endocrinology, December 2009, Bioscientifica

    Prof Taneli Raivio

  61. Frequency of Impaired Fibroblast Growth Factor Receptor 1 Signaling as a Cause of Normosmic Idiopathic Hypogonadotropic Hypogonadism

    Article • Molecular Endocrinology, December 2009, Endocrine Society

    Richard Quinton, Prof Taneli Raivio, Dr Andrew A Dwyer

  62. Impaired Fibroblast Growth Factor Receptor 1 Signaling as a Cause of Normosmic Idiopathic Hypogonadotropic Hypogonadism

    Article • The Journal of Clinical Endocrinology & Metabolism, November 2009, Endocrine Society

    Richard Quinton, Prof Taneli Raivio, Dr Andrew A Dwyer

  63. Circulating Adiponectin as a Marker for Glucocorticoid-related Side Effects in Children and Adolescents With Inflammatory Bowel Disease

    Article • Journal of Pediatric Gastroenterology and Nutrition, April 2009, Wolters Kluwer Health

    Prof Taneli Raivio

  64. Circulating Glucocorticoid Bioactivity During Peroral Glucocorticoid Treatment in Children and Adolescents With Inflammatory Bowel Disease

    Article • Journal of Clinical Gastroenterology, October 2008, Wolters Kluwer Health

    Prof Taneli Raivio

  65. Bone turnover and metabolism in paediatric patients with inflammatory bowel disease treated with systemic glucocorticoids

    Article • European Journal of Endocrinology, August 2008, Bioscientifica

    Prof Taneli Raivio

  66. Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice

    Article • Journal of Clinical Investigation, August 2008, American Society for Clinical Investigation

    Richard Quinton, Prof Taneli Raivio, Dr Andrew A Dwyer

  67. Relative Roles of Inhibin B and Sex Steroids in the Negative Feedback Regulation of Follicle-Stimulating Hormone in Men across the Full Spectrum of Seminiferous Epithelium Function

    Article • The Journal of Clinical Endocrinology & Metabolism, May 2008, Endocrine Society

    Prof Taneli Raivio, Dr Andrew A Dwyer

  68. Reversal of Idiopathic Hypogonadotropic Hypogonadism

    Article • New England Journal of Medicine, August 2007, New England Journal of Medicine (NEJM/MMS)

    Richard Quinton, Prof Taneli Raivio, Dr Andrew A Dwyer

  69. Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism

    Article • Journal of Clinical Investigation, February 2007, American Society for Clinical Investigation

    Richard Quinton, Prof Taneli Raivio, Dr Andrew A Dwyer

  70. The effects of short-term oral phytoestrogen supplementation on the hypothalamic-pituitary-testicular axis in prostate cancer patients

    Article • The Prostate, July 2006, Wiley

    Prof Taneli Raivio

  71. Are Adolescent Boys with Klinefelter Syndrome Androgen Deficient? A Longitudinal Study of Finnish 47,XXY Boys

    Article • Pediatric Research, June 2006, Nature

    Prof Taneli Raivio

  72. Genetic features of the X chromosome affect pubertal development and testicular degeneration in adolescent boys with Klinefelter syndrome

    Article • Clinical Endocrinology, June 2006, Wiley

    Prof Taneli Raivio

  73. Methylprednisolone Exposure in Pediatric Renal Transplant Patients

    Article • American Journal of Transplantation, June 2006, Wiley

    Prof Taneli Raivio

  74. Identification of glucocorticoid-response genes in children with acute lymphoblastic leukemia

    Article • Blood, March 2006, American Society of Hematology

    Prof Taneli Raivio

  75. Fecal calprotectin remains high during glucocorticoid therapy in children with inflammatory bowel disease

    Article • Scandinavian Journal of Gastroenterology, January 2006, Taylor & Francis

    Prof Taneli Raivio

  76. Mifepristone may inhibit the midcycle gonadotropin surge at both ovarian and pituitary sites of action

    Article • Fertility and Sterility, November 2005, Elsevier

    Prof Taneli Raivio

  77. Circulating Antiandrogenic Activity in Children with Congenital Adrenal Hyperplasia during Peroral Flutamide Treatment

    Article • The Journal of Clinical Endocrinology & Metabolism, September 2005, Endocrine Society

    Prof Taneli Raivio, Dr Matti Hero

  78. Late follicular phase administration of mifepristone suppresses circulating leptin and FSH - mechanism(s) of action in emergency contraception?

    Article • European Journal of Endocrinology, March 2005, Bioscientifica

    Prof Taneli Raivio

  79. Circulating Glucocorticoid Bioactivity in the Preterm Newborn after Antenatal Betamethasone Treatment

    Article • The Journal of Clinical Endocrinology & Metabolism, August 2004, Endocrine Society

    Prof Taneli Raivio

  80. Klinefelter Syndrome in Adolescence: Onset of Puberty Is Associated with Accelerated Germ Cell Depletion

    Article • The Journal of Clinical Endocrinology & Metabolism, May 2004, Endocrine Society

    Prof Taneli Raivio

  81. Serum Androgen Bioactivity in Adolescence: A Longitudinal Study of Boys with Constitutional Delay of Puberty

    Article • The Journal of Clinical Endocrinology & Metabolism, March 2004, Endocrine Society

    Prof Taneli Raivio

  82. Serum Androgen Bioactivity in Cryptorchid and Noncryptorchid Boys during the Postnatal Reproductive Hormone Surge

    Article • The Journal of Clinical Endocrinology & Metabolism, June 2003, Endocrine Society

    Prof Taneli Raivio

  83. Reduced circulating androgen bioactivity in patients with prostate cancer

    Article • The Prostate, May 2003, Wiley

    Prof Taneli Raivio

  84. Termination of Pregnancy with Mifepristone and Prostaglandin Suppresses Transiently Circulating Glucocorticoid Bioactivity

    Article • The Journal of Clinical Endocrinology & Metabolism, January 2003, Endocrine Society

    Prof Taneli Raivio

  85. Transactivation Assay for Determination of Glucocorticoid Bioactivity in Human Serum

    Article • The Journal of Clinical Endocrinology & Metabolism, August 2002, Endocrine Society

    Prof Taneli Raivio

  86. Inhibins in childhood and puberty

    Article • Best Practice & Research Clinical Endocrinology & Metabolism, March 2002, Elsevier

    Prof Taneli Raivio

  87. Activation of the Bone Morphogenetic Protein Signaling Pathway Induces Inhibin βB-Subunit mRNA and Secreted Inhibin B Levels in Cultured Human Granulosa-Luteal Cells

    Article • The Journal of Clinical Endocrinology & Metabolism, March 2002, Endocrine Society

    Prof Taneli Raivio

  88. Novel Assay for Determination of Androgen Bioactivity in Human Serum1

    Article • The Journal of Clinical Endocrinology & Metabolism, March 2001, Endocrine Society

    Prof Taneli Raivio

  89. Inverse Relationship between Serum Inhibin B and FSH Levels in Prepubertal Boys with Cryptorchidism

    Article • Pediatric Research, November 1999, Nature

    Prof Taneli Raivio

  90. Biphasic Increase in Serum Inhibin B during Puberty: A Longitudinal Study of Healthy Finnish Boys

    Article • Pediatric Research, October 1998, Nature

    Prof Taneli Raivio

  91. Treatment of prepubertal gonadotrophin-deficient boys with recombinant human follicle-stimulating hormone

    Article • The Lancet, July 1997, Elsevier

    Prof Taneli Raivio

  92. Circulating luteinizing hormone receptor inhibitor(s) in boys with chronic renal failure

    Article • Kidney International, March 1997, Elsevier

    Prof Taneli Raivio