All Stories

  1. SAXS-A-FOLD: a website for fast ensemble modeling optimizing the fit of AlphaFold or user-supplied protein structures with flexible regions to SAXS data

    Article • Journal of Applied Crystallography, May 2025, International Union of Crystallography

    Dr Mattia Rocco

  2. Bead model hydrodynamics: an in-depth comparison between GRPY and ZENO

    Article • European Biophysics Journal, May 2025, Springer Science + Business Media

    Dr Mattia Rocco

  3. AlphaFold-predicted protein structures and small-angle X-ray scattering: insights from an extended examination of selected data in the Small-Angle Scattering Biological Data Bank

    Article • Journal of Applied Crystallography, July 2023, International Union of Crystallography

    Dr Mattia Rocco

  4. Beyond the US-SOMO-AF database: a new website for hydrodynamic, structural, and circular dichroism calculations on user-supplied structures

    Article • European Biophysics Journal, February 2023, Springer Science + Business Media

    Dr Mattia Rocco

  5. A round-robin approach provides a detailed assessment of biomolecular small-angle scattering data reproducibility and yields consensus curves for benchmarking

    Article • Acta Crystallographica Section D Structural Biology, October 2022, International Union of Crystallography

    Prof. Jill Trewhella, Dr Mattia Rocco

  6. Light Scattering and Turbidimetry Techniques for the Characterization of Nanoparticles and Nanostructured Networks

    Article • Nanomaterials, June 2022, MDPI AG

    Dr Mattia Rocco

  7. A database of calculated solution parameters for the AlphaFold predicted protein structures

    Article • Scientific Reports, May 2022, Springer Science + Business Media

    Dr Mattia Rocco

  8. US-SOMO: Methods for Construction and Hydration of Macromolecular Hydrodynamic Models

    Article • January 2021, Springer Science + Business Media

    Dr Mattia Rocco

  9. Enhanced therapeutic index of liposomal doxorubicin Myocet locally delivered by fibrin gels in immunodeficient mice bearing human neuroblastoma

    Article • Pharmacological Research, January 2021, Elsevier

    Dr Mattia Rocco

  10. Fibrinogen αC‐regions are not directly involved in fibrin polymerization as evidenced by a “Double‐Detroit” recombinant fibrinogen mutant and knobs‐mimic peptides

    Article • Journal of Thrombosis and Haemostasis, January 2020, Wiley

    Dr Mattia Rocco

  11. Professor Russell F. Doolittle (1931‐2019)

    Article • Journal of Thrombosis and Haemostasis, January 2020, Wiley

    Dr Mattia Rocco

  12. Fibrin gels entrapment of a doxorubicin-containing targeted polycyclodextrin: Evaluation of in vivo antitumor activity in orthotopic models of human neuroblastoma

    Article • Toxicology and Applied Pharmacology, November 2019, Elsevier

    Dr Mattia Rocco

  13. Characterization of drug release from fibrin gels loaded with different pharmaceutical and experimental doxorubicin formulations

    Article • Pharmacological Reports, August 2018, Elsevier

    Dr Mattia Rocco

  14. Recent advances in the UltraScan SOlution MOdeller (US-SOMO) hydrodynamic and small-angle scattering data analysis and simulation suite

    Article • European Biophysics Journal, March 2018, Springer Science + Business Media

    Dr Mattia Rocco

  15. New doxorubicin nanocarriers based on cyclodextrins

    Article • Investigational New Drugs, April 2017, Springer Science + Business Media

    Dr Mattia Rocco, Giovanni Lentini

  16. Correction to Size and Density of Fibers in Fibrin and Other Filamentous Networks from Turbidimetry: Beyond a Revisited Carr–Hermans Method, Accounting for Fractality and Porosity

    Article • Macromolecules, February 2017, American Chemical Society (ACS)

    Dr Mattia Rocco

  17. Modeling of Fibrin Gels Based on Confocal Microscopy and Light-Scattering Data

    Article • Biophysical Journal, January 2017, Elsevier

    Dr Mattia Rocco

  18. Biomembrane solubilization mechanism by Triton X-100: a computational study of the three stage model

    Article • Physical Chemistry Chemical Physics, January 2017, Royal Society of Chemistry

    Dr Mattia Rocco

  19. US-SOMO HPLC-SAXS module: dealing with capillary fouling and extraction of pure component patterns from poorly resolved SEC-SAXS data

    Article • Journal of Applied Crystallography, September 2016, International Union of Crystallography

    Dr Mattia Rocco

  20. Geena 2, improved automated analysis of MALDI/TOF mass spectra

    Article • BMC Bioinformatics, February 2016, Springer Science + Business Media

    Dr Mattia Rocco

  21. Calculation of Hydrodynamic Parameters: US-SOMO

    Article • January 2016, Springer Science + Business Media

    Dr Mattia Rocco

  22. Fibrin gels loaded with cisplatin and cisplatin-hyaluronate complexes tested in a subcutaneous human melanoma model

    Article • Investigational New Drugs, October 2015, Springer Science + Business Media

    Dr Mattia Rocco

  23. Self-Assembly of Triton X-100 in Water Solutions: A Multiscale Simulation Study Linking Mesoscale to Atomistic Models

    Article • Journal of Chemical Theory and Computation, August 2015, American Chemical Society (ACS)

    Dr Mattia Rocco

  24. Size and Density of Fibers in Fibrin and Other Filamentous Networks from Turbidimetry: Beyond a Revisited Carr–Hermans Method, Accounting for Fractality and Porosity

    Article • Macromolecules, July 2015, American Chemical Society (ACS)

    Dr Mattia Rocco

  25. Erratum to: Computing translational diffusion and sedimentation coefficients: an evaluation of experimental data and programs

    Article • European Biophysics Journal, July 2015, Springer Science + Business Media

    Dr Mattia Rocco

  26. Computing translational diffusion and sedimentation coefficients: an evaluation of experimental data and programs

    Article • European Biophysics Journal, June 2015, Springer Science + Business Media

    Dr Mattia Rocco

  27. Matrix-assisted laser desorption/ionisation (MALDI) TOF analysis identifies serum angiotensin II concentrations as a strong predictor of all-cause and breast cancer (BCa)-specific mortality following breast surgery

    Article • International Journal of Cancer, June 2015, Wiley

    Dr Mattia Rocco

  28. Exposed: the elusive αC regions in fibrinogen, fibrin protofibrils and fibers

    Article • Journal of Thrombosis and Haemostasis, January 2015, Wiley

    Dr Mattia Rocco

  29. Hydrodynamic Modeling and Its Application in AUC

    Article • January 2015, Elsevier

    Dr Mattia Rocco

  30. A Comprehensive Mechanism of Fibrin Network Formation Involving Early Branching and Delayed Single- to Double-Strand Transition from Coupled Time-Resolved X-ray/Light-Scattering Detection

    Article • Journal of the American Chemical Society, April 2014, American Chemical Society (ACS)

    Dr Mattia Rocco

  31. Dynamical Aspects of Biomacromolecular Multi-resolution Modelling Using the UltraScan Solution Modeler (US-SOMO) Suite

    Article • December 2013, Springer Science + Business Media

    Dr Mattia Rocco

  32. Fibrinogen species as resolved by HPLC-SAXS data processing within theUltraScan Solution Modeler(US-SOMO) enhanced SAS module

    Article • Journal of Applied Crystallography, November 2013, International Union of Crystallography

    Dr Mattia Rocco

  33. US-SOMO cluster methods

    Article • July 2013, ACM (Association for Computing Machinery)

    Dr Mattia Rocco

  34. Hydrodynamic characterization of recombinant human fibrinogen species

    Article • Thrombosis Research, July 2013, Elsevier

    Dr Mattia Rocco

  35. Response to “A Simplified Implementation of the Bubble Analysis of Biopolymer Networks Pores”

    Article • Biophysical Journal, June 2013, Elsevier

    Dr Mattia Rocco

  36. Complement C3f serum levels may predict breast cancer risk in women with gross cystic disease of the breast

    Article • Journal of Proteomics, June 2013, Elsevier

    Dr Mattia Rocco

  37. Modeling of Fibrin Gels Based on Confocal Microscopy and Light-Scattering Data

    Article • Biophysical Journal, March 2013, Elsevier

    Dr Mattia Rocco

  38. Fast Two-Dimensional Bubble Analysis of Biopolymer Filamentous Networks Pore Size from Confocal Microscopy Thin Data Stacks

    Article • Biophysical Journal, March 2013, Elsevier

    Dr Mattia Rocco

  39. US-SOMO: Methods for Construction and Hydration of Macromolecular Hydrodynamic Models

    Article • January 2013, Springer Science + Business Media

    Dr Mattia Rocco

  40. Ultrascan solution modeler

    Article • January 2012, ACM (Association for Computing Machinery)

    Dr Mattia Rocco

  41. The application of atmospheric pressure matrix-assisted laser desorption/ionization to the analysis of long-term cryopreserved serum peptidome

    Article • Analytical Biochemistry, October 2011, Elsevier

    Dr Mattia Rocco

  42. Solution properties of full‐length integrin αIIbβ3 refined models suggest environment‐dependent induction of alternative bent /extended resting states

    Article • European Journal of Biochemistry, July 2010, Wiley

    Dr Mattia Rocco

  43. Developments in the US‐SOMO Bead Modeling Suite: New Features in the Direct Residue‐to‐Bead Method, Improved Grid Routines, and Influence of Accessible Surface Area Screening

    Article • Macromolecular Bioscience, July 2010, Wiley

    Dr Mattia Rocco

  44. Hydrodynamic and mass spectrometry analysis of nearly-intact human fibrinogen, chicken fibrinogen, and of a substantially monodisperse human fibrinogen fragment X

    Article • Archives of Biochemistry and Biophysics, January 2010, Elsevier

    Dr Mattia Rocco, Dr Gordon A. Morris

  45. The Open AUC Project

    Article • European Biophysics Journal, March 2009, Springer Science + Business Media

    Dr Mattia Rocco

  46. The implementation of SOMO (SOlution MOdeller) in the UltraScan analytical ultracentrifugation data analysis suite: enhanced capabilities allow the reliable hydrodynamic modeling of virtually any kind of biomacromolecule

    Article • European Biophysics Journal, February 2009, Springer Science + Business Media

    Dr Mattia Rocco

  47. Integrin Conformational Regulation: Uncoupling Extension/Tail Separation from Changes in the Head Region by a Multiresolution Approach

    Article • Structure, June 2008, Elsevier

    Dr Mattia Rocco

  48. Fibrin formation on fast forward

    Article • Blood, May 2008, American Society of Hematology

    Dr Mattia Rocco

  49. Identification of a new truncated form and deamidation products of fibrinopeptide B released by thrombin from human fibrinogen

    Article • Thrombosis and Haemostasis, August 2006, Schattauer GmbH

    Dr Mattia Rocco

  50. Integrin αIIbβ3:ligand interactions are linked to binding‐site remodeling

    Article • Protein Science, August 2006, Wiley

    Dr Mattia Rocco, John Connor

  51. SOMO (SOlution MOdeler)

    Article • Structure, May 2005, Elsevier

    Dr Mattia Rocco

  52. Separation of human fibrinopeptides by capillary zone electrophoresis

    Article • Electrophoresis, February 2005, Wiley

    Dr Mattia Rocco

  53. The Disintegrin Echistatin Stabilizes Integrin αIIbβ3's Open Conformation and Promotes Its Oligomerization

    Article • Journal of Molecular Biology, October 2004, Elsevier

    Dr Mattia Rocco, John Connor

  54. The Role of Unstructured Extensions in the Rotational Diffusion Properties of a Globular Protein: The Example of the Titin I27 Module

    Article • Biophysical Journal, August 2004, Elsevier

    Dr Mattia Rocco

  55. Kinetics of Fibrinopeptide Release by Thrombin as a Function of CaCl2 Concentration:  Different Susceptibility of FPA and FPB and Evidence for a Fibrinogen Isoform-Specific Effect at Physiological Ca2+ Concentration

    Article • Biochemistry, September 2003, American Chemical Society (ACS)

    Dr Mattia Rocco

  56. Small- and wide-angle elastic light scattering study of fibrin structure

    Article • Journal of Applied Crystallography, April 2003, International Union of Crystallography

    Professor Marco De Spirito, Dr Mattia Rocco

  57. Ligand Binding Promotes the Entropy-driven Oligomerization of Integrin αIIbβ3

    Article • Journal of Biological Chemistry, November 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Mattia Rocco

  58. Structure of fibrin gels studied by elastic light scattering techniques: Dependence of fractal dimension, gel crossover length, fiber diameter, and fiber density on monomer concentration

    Article • July 2002, American Physical Society (APS)

    Dr Mattia Rocco, Professor Marco De Spirito

  59. Binding of a fibrinogen mimetic stabilizes integrin αIIbβ3's open conformation

    Article • Protein Science, August 2001, Wiley

    Dr Mattia Rocco

  60. Early Events in the Polymerization of Fibrin

    Article • Annals of the New York Academy of Sciences, June 2001, Wiley

    Dr Mattia Rocco

  61. Growth kinetics and structure of fibrin gels

    Article • February 2001, American Physical Society (APS)

    Professor Marco De Spirito, Dr Mattia Rocco

  62. On the determination of the average molecular weight, radius of gyration, and mass/length ratio of polydisperse solutions of polymerizing rod-like macromolecular monomers by multi-angle static light scattering

    Article • Macromolecular Symposia, December 2000, Wiley

    Dr Mattia Rocco

  63. Polymerization of Rod-Like Macromolecular Monomers Studied by Stopped-Flow, Multiangle Light Scattering: Set-Up, Data Processing, and Application to Fibrin Formation

    Article • Biophysical Journal, July 2000, Elsevier

    Dr Mattia Rocco

  64. Effects of Ligand-Mimetic Peptides Arg-Gly-Asp-X (X = Phe, Trp, Ser) on αIIbβ3 Integrin Conformation and Oligomerization

    Article • Biochemistry, October 1999, American Chemical Society (ACS)

    Dr Mattia Rocco

  65. 17. Solution structures of factor XIIIa-crosslinked fibrinogen oligomers

    Article • Blood Coagulation & Fibrinolysis, October 1998, Wolters Kluwer Health

    Dr Mattia Rocco

  66. 16. A low-resolution model for fibrinogen and its use in the description of the initial events in fibrin formation studied by multi-angle light scattering

    Article • Blood Coagulation & Fibrinolysis, October 1998, Wolters Kluwer Health

    Dr Mattia Rocco

  67. BEAMS (BEAds Modelling System): a set of computer programs for the generation, the visualization and the computation of the hydrodynamic and conformational properties of bead models of proteins

    Article • European Biophysics Journal, October 1997, Springer Science + Business Media

    Dr Mattia Rocco

  68. BEAMS (BEAds Modelling System): a set of computer programs for the generation, the visualization and the computation of the hydrodynamic and conformational properties of bead models of proteins

    Article • European Biophysics Journal, May 1997, Springer Science + Business Media

    Dr Mattia Rocco

  69. Induction of kinetochore‐containing micronuclei by exogenous 06‐methylguanine requires conversion of the methylated base to a nucleotide

    Article • Environmental and Molecular Mutagenesis, January 1995, Wiley

    Dr Mattia Rocco

  70. The efficiency of cysteine‐mediated intracellular retention determines the differential fate of secretory IgA and IgM in B and plasma cells

    Article • European Journal of Immunology, October 1994, Wiley

    Dr Mattia Rocco

  71. Modeling the αIIbβ3 integrin solution conformation

    Article • Protein Science, December 1993, Wiley

    Dr Mattia Rocco

  72. Dynamic light scattering studies of .alpha.IIb.beta.3 solution conformation

    Article • Biochemistry, April 1993, American Chemical Society (ACS)

    Dr Mattia Rocco

  73. Solution Structure of Human Plasma Fibronectin under Different Solvent Conditions

    Article • Journal of Molecular Biology, March 1993, Elsevier

    Dr Mattia Rocco

  74. Interaction retinol-chromatin: an analysis of DNA from vitamin A-treated V79 Chinese hamster cells

    Article • Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, January 1989, Elsevier

    Dr Mattia Rocco

  75. Models of fibronectin.

    Article • The EMBO Journal, August 1987, Wiley

    Dr Mattia Rocco

  76. Genetic damage alkylation of DNA precursor pool

    Article • Cell Biology International Reports, June 1986, Wiley

    Dr Mattia Rocco

  77. Elution of fibronectin proteolytic fragments from a hydroxyapatite chromatography column. A simple procedure for the purification of fibronectin domains

    Article • European Journal of Biochemistry, February 1985, Wiley

    Dr Mattia Rocco

  78. Conformational state of circulating human plasma fibronectin

    Article • FEBS Letters, December 1984, Wiley

    Dr Mattia Rocco

  79. Dependence of the shape of the plasma fibronectin molecule on solvent composition. Ionic strength and glycerol content.

    Article • Journal of Biological Chemistry, December 1983, Elsevier

    Dr Mattia Rocco