All Stories

  1. Genomic Epidemiology of Respiratory Syncytial Virus in a New England Hospital System, 2024

    Article • Open Forum Infectious Diseases, May 2025, Oxford University Press (OUP)

    John Connor

  2. Endothelial growth media components alter SARS-CoV-2 spike-directed growth kinetics

    Article • Journal of Virological Methods, April 2025, Elsevier

    John Connor

  3. Genomic Epidemiology of Respiratory Syncytial Virus in a New England Hospital System, 2024

    Article • February 2025, Cold Spring Harbor Laboratory Press

    John Connor

  4. Improved protein splicing through viral passaging

    Article • mBio, June 2024, ASM Journals

    John Connor

  5. Immune Signatures of SARS-CoV-2 Infection Resolution in Human Lung Tissues

    Article • March 2024, Cold Spring Harbor Laboratory Press

    John Connor

  6. Heat Inactivation of Nipah Virus for Downstream Single-Cell RNA Sequencing Does Not Interfere with Sample Quality

    Article • Pathogens, January 2024, MDPI AG

    John Connor

  7. Successful treatment of SARS-CoV-2 in an immunocompromised patient with persistent infection for 245 days: A case report

    Article • Heliyon, January 2024, Elsevier

    John Connor

  8. Single virus fingerprinting by widefield interferometric defocus-enhanced mid-infrared photothermal microscopy

    Article • Nature Communications, October 2023, Springer Science + Business Media

    John Connor

  9. Transmission Dynamics and Rare Clustered Transmission Within an Urban University Population Before Widespread Vaccination

    Article • The Journal of Infectious Diseases, October 2023, Oxford University Press (OUP)

    Professor Davidson Howes Hamer, John Connor

  10. A Recombinant Vesicular Stomatitis Virus–Based Vaccine Provides Postexposure Protection Against Bundibugyo Ebolavirus Infection

    Article • The Journal of Infectious Diseases, June 2023, Oxford University Press (OUP)

    John Connor

  11. Inactivation of Ebola Virus and SARS-CoV-2 in Cell Culture Supernatants and Cell Pellets by Gamma Irradiation

    Article • Viruses, December 2022, MDPI AG

    John Connor

  12. Comparison of BinaxNOW and SARS-CoV-2 qRT-PCR Detection of the Omicron Variant from Matched Anterior Nares Swabs

    Article • Microbiology Spectrum, December 2022, ASM Journals

    John Connor

  13. Identification of Small Molecules with Improved Potency against Orthopoxviruses from Vaccinia to Smallpox

    Article • Antimicrobial Agents and Chemotherapy, November 2022, ASM Journals

    John Connor

  14. Minimal SARS-CoV-2 classroom transmission at a large urban university experiencing repeated into campus introduction

    Article • March 2022, Cold Spring Harbor Laboratory Press

    Professor Davidson Howes Hamer, John Connor

  15. Comparison of BinaxNOW TM and SARS-CoV-2 qRT-PCR detection of the Omicron Variant from Matched Anterior Nares Swabs

    Article • February 2022, Cold Spring Harbor Laboratory Press

    John Connor

  16. Acute and Chronic Cardiovascular Manifestations of COVID-19: Role for Endotheliopathy

    Article • Methodist DeBakey Cardiovascular Journal, January 2021, Methodist DeBakey Cardiovascular Journal

    John Connor

  17. Differential Mechanisms for the Involvement of Polyamines and Hypusinated eIF5A in Ebola Virus Gene Expression

    Article • Journal of Virology, July 2018, ASM Journals

    John Connor

  18. Growth-Adaptive Mutations in the Ebola Virus Makona Glycoprotein Alter Different Steps in the Virus Entry Pathway

    Article • Journal of Virology, July 2018, ASM Journals

    John Connor

  19. Correction for Olsen et al., “Polyamines and Hypusination Are Required for Ebolavirus Gene Expression and Replication”

    Article • mBio, June 2018, ASM Journals

    John Connor

  20. Wolbachia w Stri Blocks Zika Virus Growth at Two Independent Stages of Viral Replication

    Article • mBio, May 2018, ASM Journals

    John Connor

  21. Group BWolbachiaStrain-Dependent Inhibition of Arboviruses

    Article • DNA and Cell Biology, January 2018, Mary Ann Liebert Inc

    John Connor

  22. Comparison of Transcriptomic Platforms for Analysis of Whole Blood from Ebola-Infected Cynomolgus Macaques

    Article • Scientific Reports, November 2017, Springer Science + Business Media

    John Connor

  23. An RNA polymerase II-driven Ebola virus minigenome system as an advanced tool for antiviral drug screening

    Article • Antiviral Research, October 2017, Elsevier

    John Connor

  24. HoTResDB: host transcriptional response database for viral hemorrhagic fevers

    Article • Bioinformatics, September 2017, Oxford University Press (OUP)

    John Connor

  25. Host Transcriptional Response to Ebola Virus Infection

    Article • Vaccines, September 2017, MDPI AG

    John Connor

  26. Polyamines and Their Role in Virus Infection

    Article • Microbiology and Molecular Biology Reviews, September 2017, ASM Journals

    John Connor

  27. Enhanced light microscopy visualization of virus particles from Zika virus to filamentous ebolaviruses

    Article • PLOS One, June 2017, PLOS

    John Connor

  28. Spontaneous Mutation at Amino Acid 544 of the Ebola Virus Glycoprotein Potentiates Virus Entry and Selection in Tissue Culture

    Article • Journal of Virology, May 2017, ASM Journals

    John Connor

  29. Variable Inhibition of Zika Virus Replication by Different Wolbachia Strains in Mosquito Cell Cultures

    Article • Journal of Virology, April 2017, ASM Journals

    John Connor

  30. Zika virus induced cellular remodelling

    Article • Cellular Microbiology, April 2017, Wiley

    John Connor

  31. Hypusination of eIF5A as a Target for Antiviral Therapy

    Article • DNA and Cell Biology, March 2017, Mary Ann Liebert Inc

    John Connor

  32. Robust Visualization and Discrimination of Nanoparticles by Interferometric Imaging

    Article • IEEE Journal of Selected Topics in Quantum Electronics, March 2017, Institute of Electrical & Electronics Engineers (IEEE)

    John Connor

  33. Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus

    Article • Genome Biology, January 2017, Springer Science + Business Media

    John Connor

  34. Disposable cartridge platform for rapid detection of viral hemorrhagic fever viruses

    Article • Lab on a Chip, January 2017, Royal Society of Chemistry

    John Connor

  35. DNA-Directed Antibody Immobilization for Robust Protein Microarrays: Application to Single Particle Detection ‘DNA-Directed Antibody Immobilization

    Article • January 2017, Springer Science + Business Media

    John Connor

  36. Generating Recombinant Vesicular Stomatitis Viruses for Use as Vaccine Platforms

    Article • January 2017, Springer Science + Business Media

    John Connor

  37. In vivo Ebola virus infection leads to a strong innate response in circulating immune cells

    Article • BMC Genomics, September 2016, Springer Science + Business Media

    John Connor

  38. Multiplexed Metagenomic Deep Sequencing To Analyze the Composition of High-Priority Pathogen Reagents

    Article • mSystems, August 2016, ASM Journals

    John Connor

  39. Polyamines and Hypusination Are Required for Ebolavirus Gene Expression and Replication

    Article • mBio, July 2016, ASM Journals

    John Connor

  40. New Approaches for Virus Detection through Multidisciplinary Partnerships

    Article • ACS Infectious Diseases, May 2016, American Chemical Society (ACS)

    John Connor

  41. Real-Time Capture and Visualization of Individual Viruses in Complex Media

    Article • ACS Nano, January 2016, American Chemical Society (ACS)

    John Connor

  42. DNA-Directed Antibody Immobilization for Enhanced Detection of Single Viral Pathogens

    Article • Analytical Chemistry, October 2015, American Chemical Society (ACS)

    John Connor

  43. Transcriptional Profiling of the Immune Response to Marburg Virus Infection

    Article • Journal of Virology, July 2015, ASM Journals

    John Connor

  44. Temporal Characterization of Marburg Virus Angola Infection following Aerosol Challenge in Rhesus Macaques

    Article • Journal of Virology, July 2015, ASM Journals

    John Connor

  45. A Single-Vector, Single-Injection Trivalent Filovirus Vaccine: Proof of Concept Study in Outbred Guinea Pigs

    Article • The Journal of Infectious Diseases, May 2015, Oxford University Press (OUP)

    John Connor

  46. Advancing Rapid Point-Of-Care Viral Diagnostics to a Clinical Setting

    Article • Future Virology, March 2015, Taylor & Francis

    John Connor

  47. Probing the Virus Host Interaction in High Containment: An Approach Using Pooled Short Hairpin RNA

    Article • Assay and Drug Development Technologies, February 2015, Mary Ann Liebert Inc

    John Connor

  48. Transcriptional Correlates of Disease Outcome in Anticoagulant-Treated Non-Human Primates Infected with Ebolavirus

    Article • PLoS Neglected Tropical Diseases, July 2014, PLOS

    John Connor

  49. Discovery of a Novel Compound with Anti-Venezuelan Equine Encephalitis Virus Activity That Targets the Nonstructural Protein 2

    Article • PLoS Pathogens, June 2014, PLOS

    John Connor

  50. A single vertebrate DNA virus protein disarms invertebrate immunity to RNA virus infection

    Article • eLife, June 2014, eLife

    John Connor, John Yates

  51. Digital Sensing and Sizing of Vesicular Stomatitis Virus Pseudotypes in Complex Media: A Model for Ebola and Marburg Detection

    Article • ACS Nano, June 2014, American Chemical Society (ACS)

    John Connor

  52. Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

    Article • Journal of Visualized Experiments, May 2014, MyJove Corporation

    John Connor

  53. Activation of Stress Response Pathways Promotes Formation of Antiviral Granules and Restricts Virus Replication

    Article • Molecular and Cellular Biology, March 2014, ASM Journals

    John Connor

  54. The Master Regulator of the Cellular Stress Response (HSF1) Is Critical for Orthopoxvirus Infection

    Article • PLoS Pathogens, February 2014, PLOS

    John Connor

  55. Lassa and Marburg viruses elicit distinct host transcriptional responses early after infection

    Article • BMC Genomics, January 2014, Springer Science + Business Media

    John Connor

  56. An Interferometric Reflectance Imaging Sensor for Point of Care Viral Diagnostics

    Article • IEEE Transactions on Biomedical Engineering, December 2013, Institute of Electrical & Electronics Engineers (IEEE)

    John Connor

  57. Approaches for antiviral probe development: new libraries, new mechanisms

    Article • Future Virology, July 2013, Future Medicine

    John Connor

  58. Transcriptional Profiling of the Circulating Immune Response to Lassa Virus in an Aerosol Model of Exposure

    Article • PLoS Neglected Tropical Diseases, April 2013, PLOS

    John Connor

  59. Identification of a Broad-Spectrum Inhibitor of Viral RNA Synthesis: Validation of a Prototype Virus-Based Approach

    Article • Chemistry & Biology, March 2013, Elsevier

    John Connor

  60. Myxoma and Vaccinia Viruses Bind Differentially to Human Leukocytes

    Article • Journal of Virology, February 2013, ASM Journals

    John Connor, Professor Grant McFadden

  61. Translational control by negative-strand RNA viruses: Methods for the study of a crucial virus/host interaction

    Article • Methods, February 2013, Elsevier

    John Connor

  62. A point-of-care diagnostic prototype for high-throughput, multiplexed single-virus detection

    Article • September 2012, Institute of Electrical & Electronics Engineers (IEEE)

    John Connor

  63. Label-Free Optical Biosensors for Virus Detection and Characterization

    Article • IEEE Journal of Selected Topics in Quantum Electronics, July 2012, Institute of Electrical & Electronics Engineers (IEEE)

    John Connor

  64. A Vesiculovirus Showing a Steepened Transcription Gradient and Dominanttrans-Repression of Virus Transcription

    Article • Journal of Virology, June 2012, ASM Journals

    John Connor

  65. In vitro inhibition of monkeypox virus production and spread by Interferon-β

    Article • Virology Journal, January 2012, Springer Science + Business Media

    John Connor

  66. Single nanoparticle detectors for biological applications

    Article • Nanoscale, January 2012, Royal Society of Chemistry

    John Connor

  67. HijAkt

    Article • January 2012, Elsevier

    John Connor

  68. Identification of a Pyridopyrimidinone Inhibitor of Orthopoxviruses from a Diversity-Oriented Synthesis Library

    Article • Journal of Virology, December 2011, ASM Journals

    John Connor

  69. Therapeutics of Ebola Hemorrhagic Fever: Whole-Genome Transcriptional Analysis of Successful Disease Mitigation

    Article • The Journal of Infectious Diseases, November 2011, Oxford University Press (OUP)

    John Connor

  70. Ultrasensitive plasmonic fano sensor enables seeing protein monolayers with naked eye

    Article • October 2011, Institute of Electrical & Electronics Engineers (IEEE)

    John Connor

  71. Integrating microfluidic sample concentrator with Interferometric Reflectance Imaging Sensor for point-of-care viral identification

    Article • August 2011, Institute of Electrical & Electronics Engineers (IEEE)

    John Connor

  72. Interferometric Reflectance Imaging Sensor for point-of-care viral identification

    Article • August 2011, Institute of Electrical & Electronics Engineers (IEEE)

    John Connor

  73. Label-free pathogen sensing: Microarray studies for clinical and research applictions

    Article • August 2011, Institute of Electrical & Electronics Engineers (IEEE)

    John Connor

  74. Development of Vaccinia reporter viruses for rapid, high content analysis of viral function at all stages of gene expression

    Article • Antiviral Research, July 2011, Elsevier

    John Connor

  75. Seeing protein monolayers with naked eye through plasmonic Fano resonances

    Article • Proceedings of the National Academy of Sciences, June 2011, Proceedings of the National Academy of Sciences

    John Connor

  76. Biomolecular Detection employing the Interferometric Reflectance Imaging Sensor (IRIS)

    Article • Journal of Visualized Experiments, May 2011, MyJove Corporation

    John Connor

  77. Label-free multiplexed virus detection using spectral reflectance imaging

    Article • Biosensors and Bioelectronics, April 2011, Elsevier

    John Connor

  78. Formation of Antiviral Cytoplasmic Granules during Orthopoxvirus Infection

    Article • Journal of Virology, December 2010, ASM Journals

    John Connor

  79. An Optofluidic Nanoplasmonic Biosensor for Direct Detection of Live Viruses from Biological Media

    Article • Nano Letters, November 2010, American Chemical Society (ACS)

    John Connor

  80. Dominant Inhibition of Akt/Protein Kinase B Signaling by the Matrix Protein of a Negative-Strand RNA Virus

    Article • Journal of Virology, October 2010, ASM Journals

    John Connor

  81. Inhibition of heat-shock protein 90 reduces Ebola virus replication

    Article • Antiviral Research, August 2010, Elsevier

    John Connor

  82. Spectral Reflectance Imaging for a Multiplexed, High-Throughput, Label-Free, and Dynamic Biosensing Platform

    Article • IEEE Journal of Selected Topics in Quantum Electronics, January 2010, Institute of Electrical & Electronics Engineers (IEEE)

    John Connor

  83. Akt Inhibitor Akt-IV Blocks Virus Replication through an Akt-Independent Mechanism

    Article • Journal of Virology, September 2009, ASM Journals

    John Connor

  84. Murine B Cell Response to TLR7 Ligands Depends on an IFN-β Feedback Loop

    Article • The Journal of Immunology, August 2009, Oxford University Press (OUP)

    John Connor

  85. Capture and transfer of HIV-1 particles by mature dendritic cells converges with the exosome-dissemination pathway

    Article • Blood, January 2009, American Society of Hematology

    Dr Suryaram Gummuluru, John Connor

  86. Vesicular Stomatitis Virus Matrix Protein Mutations That Affect Association with Host Membranes and Viral Nucleocapsids

    Article • Journal of Biological Chemistry, December 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    John Connor

  87. hnRNPs Relocalize to the Cytoplasm following Infection with Vesicular Stomatitis Virus

    Article • Journal of Virology, November 2008, ASM Journals

    John Connor

  88. New mRNAs Are Preferentially Translated during Vesicular Stomatitis Virus Infection

    Article • Journal of Virology, December 2007, ASM Journals

    John Connor

  89. Antiviral activity and RNA polymerase degradation following Hsp90 inhibition in a range of negative strand viruses

    Article • Virology, May 2007, Elsevier

    John Connor

  90. αIIbβ3 priming and clustering by orally active and intravenous integrin antagonists

    Article • Journal of Thrombosis and Haemostasis, March 2007, Elsevier

    John Connor

  91. Preferential Translation of Vesicular Stomatitis Virus mRNAs Is Conferred by Transcription from the Viral Genome

    Article • Journal of Virology, September 2006, ASM Journals

    John Connor

  92. Integrin αIIbβ3:ligand interactions are linked to binding‐site remodeling

    Article • Protein Science, August 2006, Wiley

    Dr Mattia Rocco, John Connor

  93. Role of Residues 121 to 124 of Vesicular Stomatitis Virus Matrix Protein in Virus Assembly and Virus-Host Interaction

    Article • Journal of Virology, April 2006, ASM Journals

    John Connor

  94. Inhibition of Host and Viral Translation during Vesicular Stomatitis Virus Infection: eIF2 IS RESPONSIBLE FOR THE INHIBITION OF VIRAL BUT NOT HOST TRANSLATION

    Article • Journal of Biological Chemistry, February 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    John Connor

  95. The Disintegrin Echistatin Stabilizes Integrin αIIbβ3's Open Conformation and Promotes Its Oligomerization

    Article • Journal of Molecular Biology, October 2004, Elsevier

    Dr Mattia Rocco, John Connor

  96. Replication and Cytopathic Effect of Oncolytic Vesicular Stomatitis Virus in Hypoxic Tumor Cells In Vitro and In Vivo

    Article • Journal of Virology, September 2004, ASM Journals

    John Connor

  97. Deactylase Inhibitors Disrupt Cellular Complexes Containing Protein Phosphatases and Deacetylases

    Article • Journal of Biological Chemistry, December 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    John Connor

  98. Vesicular Stomatitis Virus Infection Alters the eIF4F Translation Initiation Complex and Causes Dephosphorylation of the eIF4E Binding Protein 4E-BP1

    Article • Journal of Virology, October 2002, ASM Journals

    John Connor

  99. The Neuronal Actin-binding Proteins, Neurabin I and Neurabin II, Recruit Specific Isoforms of Protein Phosphatase-1 Catalytic Subunits

    Article • Journal of Biological Chemistry, August 2002, Elsevier

    John Connor

  100. Regulation of Synaptic Strength by Protein Phosphatase 1

    Article • Neuron, December 2001, Elsevier

    John Connor

  101. Growth Arrest and DNA Damage-Inducible Protein GADD34 Assembles a Novel Signaling Complex Containing Protein Phosphatase 1 and Inhibitor 1

    Article • Molecular and Cellular Biology, October 2001, ASM Journals

    John Connor

  102. Molecular memory by reversible translocation of calcium/calmodulin-dependent protein kinase II

    Article • Nature Neuroscience, September 2000, Springer Science + Business Media

    Mary Teruel, John Connor

  103. Cellular Mechanisms Regulating Protein Phosphatase-1

    Article • Journal of Biological Chemistry, June 2000, Elsevier

    John Connor

  104. Neurofilament-L Is a Protein Phosphatase-1-binding Protein Associated with Neuronal Plasma Membrane and Post-synaptic Density

    Article • Journal of Biological Chemistry, January 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    John Connor

  105. Importance of the  12- 13 Loop in Protein Phosphatase-1 Catalytic Subunit for Inhibition by Toxins and Mammalian Protein Inhibitors

    Article • Journal of Biological Chemistry, August 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    John Connor

  106. Molecular Determinants of Nuclear Protein Phosphatase-1 Regulation by NIPP-1

    Article • Journal of Biological Chemistry, May 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    John Connor

  107. Inhibitor-1 Interaction Domain That Mediates the Inhibition of Protein Phosphatase-1

    Article • Journal of Biological Chemistry, October 1998, American Society for Biochemistry & Molecular Biology (ASBMB)

    John Connor

  108. Gating of CaMKII by cAMP-Regulated Protein Phosphatase Activity During LTP

    Article • Science, June 1998, American Association for the Advancement of Science

    John Connor

  109. Inhibitor-1, a Regulator of Protein Phosphatase 1 Function

    Article • January 1998, Springer Science + Business Media

    John Connor

  110. Conversion of Protein Phosphatase 1 Catalytic Subunit to a Mn 2+ -Dependent Enzyme Impairs Its Regulation by Inhibitor 1 †

    Article • Biochemistry, June 1997, American Chemical Society (ACS)

    John Connor

  111. Multiple Structural Elements Define the Specificity of Recombinant Human Inhibitor-1 as a Protein Phosphatase-1 Inhibitor † , ‡

    Article • Biochemistry, January 1996, American Chemical Society (ACS)

    John Connor

  112. Abstract

    Article • eLife

    John Connor