All Stories

  1. SMuRF-less, not risk-less: persistence matters after STEMI
  2. Targeting ATP-Citrate Lyase Across Cardiometabolic and Oncologic Disease
  3. LDL-Cholesterol Distance to Target: A Practical Tool for Guiding Lipid-Lowering Treatment Decisions
  4. Contemporary Overview of Aortic Regurgitation in Young Individuals: Insights From Real‐Life Evidence
  5. Plasma PCSK9 levels in children and adolescents: evidence from an Italian outpatient paediatric clinic cohort at cardio-metabolic risk.
  6. Echocardiographic Atrial and Right Heart to Pulmonary Circulation Coupling Indices Identify High-Risk in Moderate Aortic Stenosis
  7. What Should a Clinical Cardiologist Know About Cardiogenetics?
  8. Inhibition of ATP citrate lyase does not affect muscle mitochondrial activity in apoE-/- mice
  9. Interplay among lipoprotein(a), hepatic and vascular damage in individuals with metabolic dysfunction
  10. The role of the PPAR system in diabetic cardiovascular risk and beyond
  11. From clinical inertia to therapeutic optimization in patients with atherosclerotic cardiovascular disease: A Monte Carlo simulation within the ITACARE-P registry
  12. Reduction of visit-to-visit LDL-C intraindividual variability in patients treated with PCSK9 inhibitors and inclisiran vs standard lipid-lowering therapy
  13. Regulation of Monocyte Perilipin-2 Expression in Acute and Chronic Coronary Syndromes: Pathogenetic Implications
  14. Peak atrial longitudinal strain to catch atrial fibrillation in patients in sinus rhythm admitted for cerebral ischaemic events
  15. Aspirin and lipoprotein(a): lessons from replication at scale
  16. The role of extracellular vesicle-derived miRNA in the atherosclerotic burden
  17. PCSK9 genetic variants, carotid atherosclerosis and vascular remodelling
  18. Phytosterols and phytostanols in context: From physiology and pathophysiology to food supplementation and clinical practice
  19. Diagnostic Algorithm Using Multimodal Imaging for the Differential Diagnosis of Intra-Cardiac Masses
  20. Long‐term fasting induces a remodelling of fatty acid composition in erythrocyte membranes
  21. Cardiometabolic risk factors in adults with cystic fibrosis undergoing elexacaftor/tezacaftor/ivacaftor therapy
  22. Lipoprotein(a) and the atherosclerotic burden – Should we wait for clinical trial evidence before taking action?
  23. Generalized arterial calcifications in a twin recipient treated with etidronate: description of a case report within a narrative review
  24. Hypercholesterolemia and inflammation—Cooperative cardiovascular risk factors
  25. HDL cholesterol efflux capacity and cholesterol loading capacity in long-term fasting: Evidence from a prospective, single-arm interventional study in healthy individuals
  26. Causal associations between insulin and Lp(a) levels in Caucasian population: a Mendelian randomization study
  27. Concordance between Coronary Artery Computed Tomography and Invasive Coronary Angiography in a Real-World Population with Suspected Chronic Coronary Syndrome
  28. Correction: Ferri et al. Low-Density Lipoprotein Cholesterol-Lowering Drugs: A Narrative Review. J. Clin. Med. 2024, 13, 943
  29. Anticancer Activity of Delta-Tocotrienol in Human Hepatocarcinoma: Involvement of Autophagy Induction
  30. Imaging approaches in risk stratification of patients with coronary artery disease: a narrative review
  31. Prognostic Value of PCSK9 Levels in Premenopausal Women at Risk of Breast Cancer—Evidence from a 17-Year Follow-Up Study
  32. Exploring the role of epicardial adipose-tissue-derived extracellular vesicles in cardiovascular diseases
  33. Low-Density Lipoprotein Cholesterol-Lowering Drugs: A Narrative Review
  34. The ins and outs of lipoprotein(a) assay methods
  35. Extracellular vesicles in cardiomyopathies: A narrative review
  36. Platelet Cyclic GMP Levels Are Reduced in Patients with Primary Aldosteronism
  37. Updates in Small Interfering RNA for the Treatment of Dyslipidemias
  38. LDL Cholesterol Variability Impacts the Prognosis of Patients with Chronic Ischemic Heart Disease: A Real-World Italian Experience
  39. The “Woggle” Technique for Venous Access Site Management: An Old Technique for a New Need
  40. Right Heart Catheterization: An Antecubital Vein Approach to Reduce Fluoroscopy Time, Radiation Dose, and Guidewires Need
  41. An association study of cyclase‐associated protein 2 and frailty
  42. Induced myocardial ischemia in candidates to liver transplantation without evidence of heart disease
  43. Proteomics and Lipidomics to unveil the contribution of PCSK9 beyond cholesterol lowering: a narrative review
  44. Protocol to evaluate the impact of murine MCT1-deficient CD8+ T cells on adipogenesis
  45. Pollution from fine particulate matter and atherosclerosis: A narrative review
  46. Nutraceutical approaches to non-alcoholic fatty liver disease (NAFLD): A position paper from the International Lipid Expert Panel (ILEP)
  47. Lentilactobacillus kefiri SGL 13 and Andrographis paniculata alleviate dextran sulfate sodium induced colitis in mice
  48. Editorial: The molecular mechanisms and therapeutic targets of atherosclerosis
  49. Long-term fasting: Multi-system adaptations in humans (GENESIS) study–A single-arm interventional trial
  50. PCSK9 Inhibition and Risk of Diabetes: Should We Worry?
  51. Role of lipoprotein(a) in plaque progression
  52. PCSK9 Confers Inflammatory Properties to Extracellular Vesicles Released by Vascular Smooth Muscle Cells
  53. The role of PCSK9 in NAFLD/NASH and therapeutic implications of PCSK9 inhibition
  54. Pharmacological rationale for the very early treatment of acute coronary syndrome with monoclonal antibodies anti-PCSK9
  55. Omega-3 and cardiovascular prevention – Is this still a choice?
  56. Bempedoic Acid: for Whom and When
  57. Synovial Fluid-Derived Extracellular Vesicles of Patients with Arthritides Contribute to Hippocampal Synaptic Dysfunctions and Increase with Mood Disorders Severity in Humans
  58. Effect of Bariatric Surgery on Flow-Mediated Vasodilation as a Measure of Endothelial Function: A Systematic Review and Meta-Analysis
  59. Brain-Derived Neurotrophic Factor and Extracellular Vesicle-Derived miRNAs in an Italian Cohort of Individuals With Obesity: A Key to Explain the Link Between Depression and Atherothrombosis
  60. Monocarboxylate transporter 1 deficiency impacts CD8+ T lymphocytes proliferation and recruitment to adipose tissue during obesity
  61. HDL‐mediated reduction of cholesterol content inhibits the proliferation of prostate cancer cells induced by LDL: Role of ABCA1 and proteasome inhibition
  62. Impact of Atorvastatin on Skeletal Muscle Mitochondrial Activity, Locomotion and Axonal Excitability—Evidence from ApoE-/- Mice
  63. PCSK9 promotes arterial medial calcification
  64. Step‐by‐step diagnosis and management of the nocebo/drucebo effect in statin‐associated muscle symptoms patients: a position paper from the International Lipid Expert Panel (ILEP)
  65. The Role of High-Density Lipoprotein Cholesterol in 2022
  66. Side effects of statins: from pathophysiology and epidemiology to diagnostic and therapeutic implications
  67. Antioxidant Effects of Statins by Modulating Nrf2 and Nrf2/HO-1 Signaling in Different Diseases
  68. Research Progress on Natural Compounds Exerting an Antidepressant Effect through Anti-inflammatory
  69. PCSK9 as a New Player in Cancer: New Opportunity or Red Herring?
  70. Associations Among PCSK9 Levels, Atherosclerosis-Derived Extracellular Vesicles, and Their miRNA Content in Adults With Obesity
  71. TM6SF2/PNPLA3/MBOAT7 Loss-of-Function Genetic Variants Impact on NAFLD Development and Progression Both in Patients and in In Vitro Models
  72. The Effect of Bariatric Surgery on Circulating Levels of Lipoprotein (a): A Meta‐analysis
  73. Impact of Soy β-Conglycinin Peptides on PCSK9 Protein Expression in HepG2 Cells
  74. HDL in COVID-19 Patients: Evidence from an Italian Cross-Sectional Study
  75. Lipoprotein(a): Knowns, unknowns and uncertainties
  76. Low Lipoprotein(a) Levels Predict Hepatic Fibrosis in Patients With Nonalcoholic Fatty Liver Disease
  77. New players in the treatment of hypercholesterolaemia: focus on bempedoic acid and inclisiran
  78. Cardiovascular complications of COVID-19: toward better understanding, diagnosis, monitoring and management
  79. Proprotein Convertase Subtilisin/Kexin Type 9
  80. Relationship between Circulating PCSK9 and Markers of Subclinical Atherosclerosis—The IMPROVE Study
  81. Effects of Statins on Renin–Angiotensin System
  82. Prognostic parameters of in‐hospital mortality in COVID‐19 patients—An Italian experience
  83. Impact of nutraceuticals on markers of systemic inflammation: Potential relevance to cardiovascular diseases – A position paper from the International Lipid Expert Panel (ILEP)
  84. Reduction of Cardio-Metabolic Risk and Body Weight through a Multiphasic Very-Low Calorie Ketogenic Diet Program in Women with Overweight/Obesity: A Study in a Real-World Setting
  85. Long-term fasting improves lipoprotein-associated atherogenic risk in humans
  86. PCSK9 Induces Rat Smooth Muscle Cell Proliferation and Counteracts the Pleiotropic Effects of Simvastatin
  87. The effect of transgender hormonal treatment on high density lipoprotein cholesterol efflux capacity
  88. Maternal exposure to air pollutants, PCSK9 levels, fetal growth and gestational age – An Italian cohort
  89. Lipid Lowering Drugs: Present Status and Future Developments
  90. Nonalcoholic fatty liver disease or metabolic dysfunction‐associated fatty liver disease diagnoses and cardiovascular diseases: From epidemiology to drug approaches
  91. Gender difference in lipoprotein(a) concentration as a predictor of coronary revascularization in patients with known coronary artery disease
  92. Cyclase-associated protein 2 (CAP2) controls MRTF-A localization and SRF activity in mouse embryonic fibroblasts
  93. Cardiovascular risk and testosterone – from subclinical atherosclerosis to lipoprotein function to heart failure
  94. Effects of PM Exposure on the Methylation of Clock Genes in A Population of Subjects with Overweight or Obesity
  95. Evaluation of Transthoracic Echocardiography in the Assessment of Atherosclerosis of the Left Main Coronary Artery: Comparison with Optical Frequency Domain Imaging (a Pilot Study)
  96. TM6SF2/PNPLA3/MBOAT7 loss-of-function genetic variants impact on NAFLD development and progression both in patients and in in vitro models
  97. Serological follow-up of SARS-CoV-2 asymptomatic subjects
  98. Depression and cardiovascular risk—association among Beck Depression Inventory, PCSK9 levels and insulin resistance
  99. Leptin, Resistin, and Proprotein Convertase Subtilisin/Kexin Type 9
  100. Impact of bariatric surgery-induced weight loss on circulating PCSK9 levels in obese patients
  101. Lipoprotein(a) and PCSK9 inhibition: clinical evidence
  102. Cyclase-associated protein 2 (CAP2) controls MRTF-A localization and SRF activity in mouse embryonic fibroblasts
  103. Impact of Phyllantus niruri and Lactobacillus amylovorus SGL 14 in a mouse model of dietary hyperoxaluria
  104. PCSK9 Levels Are Raised in Chronic HCV Patients with Hepatocellular Carcinoma
  105. The Efficacy of the Mineralcorticoid Receptor Antagonist Canrenone in COVID-19 Patients
  106. Sex-specific predictors of PCSK9 levels in a European population: The IMPROVE study
  107. Clinical approach to the inflammatory etiology of cardiovascular diseases
  108. SARS-CoV-2 infection among asymptomatic homebound subjects in Milan, Italy
  109. The efficacy of mineral corticoid receptor antagonist, canrenone, in COVID-19 patients
  110. Efficacy and safety of bempedoic acid for the treatment of hypercholesterolemia: A systematic review and meta-analysis
  111. Lipoprotein(a) Lowering—From Lipoprotein Apheresis to Antisense Oligonucleotide Approach
  112. Inherited atherogenic dyslipidemias: are they correctly reported?
  113. Unravelling the health effects of fasting: a long road from obesity treatment to healthy life span increase and improved cognition
  114. PCSK9 Expression in Epicardial Adipose Tissue: Molecular Association with Local Tissue Inflammation
  115. The liaison between respiratory failure and high blood pressure: evidence from COVID-19 patients
  116. BDNF Val66Met polymorphism alters food intake and hypothalamic BDNF expression in mice
  117. Naturally Occurring PCSK9 Inhibitors
  118. The impact of type of dietary protein, animal versus vegetable, in modifying cardiometabolic risk factors: A position paper from the International Lipid Expert Panel (ILEP)
  119. Proprotein convertase subtilisin/kexin type 9: an update on the cardiovascular outcome studies
  120. Pharmacological aspects of ANGPTL3 and ANGPTL4 inhibitors: New therapeutic approaches for the treatment of atherogenic dyslipidemia
  121. Acute pericarditis in a young patient with IgG immunodeficiency
  122. Non-alcoholic fatty liver disease and cardiovascular disease: A still debated liaison
  123. Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring
  124. HDL therapy today: from atherosclerosis, to stent compatibility to heart failure
  125. Angiopoietin-like 3 and subclinical peripheral arterial disease: Evidence from the Brisighella Heart Study
  126. Correction to: Nutraceutical approach for the management of cardiovascular risk – a combination containing the probiotic Bifidobacterium longum BB536 and red yeast rice extract: results from a randomized, double-blind, placebo-controlled study
  127. Impact of PPAR-Alpha Polymorphisms—The Case of Metabolic Disorders and Atherosclerosis
  128. A NEW DAWN FOR MANAGING DYSLIPIDEMIAS: THE ERA OF RNA-BASED THERAPIES
  129. PCSK9 inhibition and inflammation: A narrative review
  130. Residual vascular risk in diabetes – Will the SPPARM alpha concept hold the key?
  131. Methotrexate for Cardiovascular Risk Reduction: The Right Choice?
  132. The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential
  133. Differential effects of red yeast rice, Berberis aristata and Morus alba extracts on PCSK9 and LDL uptake
  134. Proprotein Convertase Subtilisin/Kexin Type 9, Brain Cholesterol Homeostasis and Potential Implication for Alzheimer’s Disease
  135. Can we further optimize statin therapy to increase tolerability?
  136. Recent advances in synthetic pharmacotherapies for dyslipidaemias
  137. PCSK9 in HIV infection: New opportunity or red herring?
  138. Efficacy and Safety of Mipomersen: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
  139. Ceramides and diabetes mellitus: an update on the potential molecular relationships
  140. PCSK7 gene variation bridges atherogenic dyslipidemia with hepatic inflammation in NAFLD patients
  141. PCSK9 monoclonal antibodies and lipoprotein apheresis for lowering lipoprotein(a): making choices in an era of RNA-based therapies
  142. High-Density Lipoprotein Function Is Reduced in Patients Affected by Genetic or Idiopathic Hypogonadism
  143. Deciphering the role of V200A and N291S mutations leading to LPL deficiency
  144. ETC-1002 (Bempedoic acid) for the management of hyperlipidemia: from preclinical studies to phase 3 trials
  145. Nutraceutical approach for the management of cardiovascular risk – a combination containing the probiotic Bifidobacterium longum BB536 and red yeast rice extract: results from a randomized, double-blind, placebo-controlled study
  146. Changes in circulating pro-protein convertase subtilisin/kexin type 9 levels – experimental and clinical approaches with lipid-lowering agents
  147. Resveratrol and cognitive decline: a clinician perspective
  148. Pulse wave velocity as a measure of arterial stiffness in patients with familial hypercholesterolemia: a systematic review and meta-analysis
  149. Long-term exposure to air pollution raises circulating levels of proprotein convertase subtilisin/kexin type 9 in obese individuals
  150. MicroRNAs: Novel Molecular Targets and Response Modulators of Statin Therapy
  151. Cholesteryl ester transfer protein: An enigmatic pharmacology – Antagonists and agonists
  152. The effect of statin therapy on endoplasmic reticulum stress
  153. Left main coronary wall thickness correlates with the carotid intima media thickness and may provide a new marker of cardiovascular risk
  154. Serum irisin is upregulated in patients affected by amyotrophic lateral sclerosis and correlates with functional and metabolic status
  155. Differential Effects of Red Yeast Rice, Berberis Aristata and Morus Alba Extracts, Active Components of LopiGLIK®, on PCSK9 in HepG2 Cells
  156. Plasma PCSK9 levels and lipoprotein distribution are preserved in carriers of genetic HDL disorders
  157. Monocyte-to-HDL-cholesterol ratio as a prognostic marker in cardiovascular diseases
  158. From lipoprotein apheresis to proprotein convertase subtilisin/kexin type 9 inhibitors: Impact on low-density lipoprotein cholesterol and C-reactive protein levels in cardiovascular disease patients
  159. Lipid Lowering Drugs and Inflammatory Changes: an Impact on Cardiovascular Outcomes?
  160. PCSK9 deficiency reduces insulin secretion and promotes glucose intolerance: the role of the low-density lipoprotein receptor
  161. Effect of statin therapy on plasma apolipoprotein CIII concentrations: A systematic review and meta-analysis of randomized controlled trials
  162. PPAR Agonists and Metabolic Syndrome: An Established Role?
  163. Appropriateness of statin prescription in the elderly
  164. Body composition and metabolic changes during a 520-day mission simulation to Mars
  165. Influence of body variables in the development of metabolic syndrome—A long term follow-up study
  166. High Density Lipoproteins Inhibit Oxidative Stress-Induced Prostate Cancer Cell Proliferation
  167. PCSK9 induces a pro-inflammatory response in macrophages
  168. PCSK9 as a Positive Modulator of Platelet Activation
  169. Present therapeutic role of cholesteryl ester transfer protein inhibitors
  170. PCSK9 antagonists and inflammation
  171. Nutraceutical approaches to metabolic syndrome
  172. Bococizumab for the treatment of hypercholesterolaemia
  173. Translating the biology of adipokines in atherosclerosis and cardiovascular diseases: Gaps and open questions
  174. PPAR-α agonists are still on the rise: an update on clinical and experimental findings
  175. Effect of soy on metabolic syndrome and cardiovascular risk factors: a randomized controlled trial
  176. Proprotein convertase subtilisin kexin type 9 and high-density lipoprotein metabolism: experimental animal models and clinical evidence
  177. Increased circulating adiponectin in males with chronic HCV hepatitis
  178. Free and bound plasma leptin in anorexia nervosa patients during a refeeding program
  179. Menstrual and reproductive history and use of exogenous sex hormones and risk of thyroid cancer among women: a meta-analysis of prospective studies
  180. Risk identification and possible countermeasures for muscle adverse effects during statin therapy
  181. Changes in Stress Hormones and Metabolism During a 105-Day Simulated Mars Mission
  182. Hepatic steatosis and PNPLA3 I148M variant are associated with serum Fetuin-A independently of insulin resistance
  183. Statin therapy and related risk of new-onset type 2 diabetes mellitus
  184. Characterization and sub-cellular localization of SS1R, SS2R, and SS5R in human late-stage prostate cancer cells: Effect of mono- and bi-specific somatostatin analogs on cell growth
  185. In VitroChronic Administration of ERbeta Selective Ligands and Prostate Cancer Cell Growth: Hypotheses on the Selective Role of 3beta-Adiol in AR-Positive RV1 Cells
  186. Nutraceutical approach to moderate cardiometabolic risk: Results of a randomized, double-blind and crossover study with Armolipid Plus
  187. Antiproliferative activity on human prostate carcinoma cell lines of new peptidomimetics containing the spiroazepinoindolinone scaffold
  188. Dietary Iron Overload Induces Visceral Adipose Tissue Insulin Resistance
  189. Somatostatin, Somatostatin Analogs and Somatostatin Receptor Dynamics in the Biology of Cancer Progression
  190. Low-intermediate dose testosterone replacement therapy by different pharmaceutical preparations improves frailty score in elderly hypogonadal hyperglycaemic patients
  191. GC–MS profiling of the phytochemical constituents of the oleoresin from Copaifera langsdorffii Desf. and a preliminary in vivo evaluation of its antipsoriatic effect
  192. The i148m Pnpla3 polymorphism influences serum adiponectin in patients with fatty liver and healthy controls
  193. Parthenolide Inhibits the LPS-induced Secretion of IL-6 and TNF-α and NF-κB Nuclear Translocation in BV-2 Microglia
  194. Impaired expression of insulin-like growth factor-1 system in skeletal muscle of amyotrophic lateral sclerosis patients
  195. Prognostic Effect of Circulating Adiponectin in a Randomized 2 × 2 Trial of Low-Dose Tamoxifen and Fenretinide in Premenopausal Women at Risk for Breast Cancer
  196. Metabolic Syndrome, Adipokines and Hormonal Factors in Pharmacologically Untreated Adult Elderly Subjects from the Brisighella Heart Study Historical Cohort
  197. Adiponectin Interactions in Bone and Cartilage Biology and Disease
  198. Corrigendum to “Regulation of prostate cancer cell proliferation by somatostatin receptor activation” [Mol. Cell. Endocrinol. 315 (1–2) (2010) 254–262]
  199. Adipokines and Sexual Hormones Associated with the Components of the Metabolic Syndrome in Pharmacologically Untreated Subjects: Data from the Brisighella Heart Study
  200. Adipokine actions on cartilage homeostasis
  201. Erratum to “The natural antioxidant alpha-lipoic acid induces p27Kip1-dependent cell cycle arrest and apoptosis in MCF-7 human breast cancer cells” [Eur. J. Pharmacol. 641 (2010) 29-34]
  202. Somatostatin and dopamine receptor interaction in prostate and lung cancer cell lines
  203. The natural antioxidant alpha-lipoic acid induces p27Kip1-dependent cell cycle arrest and apoptosis in MCF-7 human breast cancer cells
  204. Pharmacokinetics of orally administered melatonin in critically ill patients
  205. Regulation of prostate cancer cell proliferation by somatostatin receptor activation
  206. Leptin, Ciliary Neurotrophic Factor, Leukemia Inhibitory Factor and Interleukin- 6: Class-I Cytokines Involved in the Neuroendocrine Regulation of the Reproductive Function
  207. Free insulin-like growth factor (IGF)-1 and IGF-binding proteins-2 and -3 in serum and cerebrospinal fluid of amyotrophic lateral sclerosis patients
  208. Feeding Behavior in Mammals Including Humans
  209. Effect of Fenretinide and Low-Dose Tamoxifen on Insulin Sensitivity in Premenopausal Women at High Risk for Breast Cancer
  210. Total, free and bound leptin and thyroid function in elderly women with different body weights
  211. Cholinergic regulation of neuropeptide Y synthesis and release in human neuroblastoma cells
  212. Relevance of the Neuropeptide Y System in the Biology of Cancer Progression
  213. Leukemia Inhibitory Factor Induces the Chemomigration of Immortalized Gonadotropin-Releasing Hormone Neurons through the Independent Activation of the Janus Kinase/Signal Transducer and Activator of Transcription 3, Mitogen-Activated Protein Kinase/Ext...
  214. A mutation and expression analysis of the oncogene BRAF in pituitary adenomas
  215. Role of neuropeptide Y and its receptors in the progression of endocrine-related cancer
  216. Hypothalamic Neuropeptide Systems as Targets for Potential Anti-Obesity Drugs
  217. Is ghrelin a signal of decreased fat-free mass in elderly subjects?
  218. Activation of the Y1 Receptor by Neuropeptide Y Regulates the Growth of Prostate Cancer Cells
  219. Expression of Functional Ciliary Neurotrophic Factor Receptors in Immortalized Gonadotrophin-Releasing Hormone-Secreting Neurones
  220. Free and bound plasma leptin in normal weight and obese men and women: relationship with body composition, resting energy expenditure, insulin-sensitivity, lipid profile and macronutrient preference
  221. Free and bound leptin in prepubertal children with Down's syndrome and different degrees of adiposity
  222. Modulatory Actions of Neuropeptide Y on Prostate Cancer Growth: Role of MAP Kinase/ERK 1/2 Activatio