Leszek Drabik

Clot permeability and risk of stroke and bleeding in atrial fibrillation.

• Stroke
• September 2017

• Fibrin is a major component of both venous and arterial thrombi including those retrieved in stroke and myocardial infarction by mechanical thrombectomy. Fibrin clot structure affects the transpo...

Fibrin clot permeability in atrial fibrillation

• Thrombosis Research
• August 2015

• Paroxysmal, persistent and permanent atrial fibrillation (AF), all significantly increase the stroke risk up to 20% annually. Available data on fibrinolysis in AF are sparse. We hypothesized that i...

CHART-1 clinical trial

• European Heart Journal
• December 2016

NOAC, cancer and atrial fibrillation

• The Anatolian Journal of Cardiology
• January 2019

• The challenges of the use of Non-vitamin K antagonist oral anticoagulants (NOACs) in cancer patients with AF and the current expert opinions on this subject have been summarized in this review arti...

The ORBIT bleeding score is associated with lysis and permeability of fibrin clots Address

• Kardiologia Polska
• October 2019

• This study demonstrates that the five-element ORBIT bleeding score which has been reported to have better ability to predict major bleeding in AF patients as compared with HAS-BLED and ATRIA risk s...

Clot Lysis Time Predicts Stroke During Anticoagulant Therapy in Patients with Atrial Fi...

• Canadian Journal of Cardiology
• August 2019

• Our findings demonstrate that in atrial fbrillation patients treated with vitamin K antagonists, impaired fibrinolysis predisposes to thromboembolism, but not to bleeding.

Bleeding in anticoagulated patients with AF: practical considerations

• Polish Archives of Internal Medicine
• January 2020

• The current review summarizes practical challenges in the management of oral anticoagulation with emphasis on the risk assessment tools, elderly or underweight patients, cancer patients, impact of ...