All Stories

  1. MYC targeting by OMO-103 in solid tumors: a phase 1 trial

    Article • Nature Reports Stem Cells, February 2024, Springer Science + Business Media

    Laura Soucek

  2. eIF4A dependency: the hidden key to unlock KRAS mutant non-small cell lung cancer’s vulnerability

    Article • Translational Lung Cancer Research, December 2023, AME Publishing Company

    Laura Soucek

  3. Reducing MYC's transcriptional footprint unveils a good prognostic gene signature in melanoma

    Article • Genes & Development, April 2023, Cold Spring Harbor Laboratory Press

    Laura Soucek

  4. Pharmacokinetic Analysis of Omomyc Shows Lasting Structural Integrity and Long Terminal Half-Life in Tumor Tissue

    Article • Cancers, January 2023, MDPI AG

    Laura Soucek

  5. Targeting MYC-driven lymphoma: lessons learned and future directions

    Article • Cancer Drug Resistance, January 2023, OAE Publishing

    Laura Soucek

  6. Going for a “KDIP” in colorectal cancer treatment

    Article • Clinical and Translational Discovery, July 2022, Wiley

    Laura Soucek

  7. MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding

    Article • Cancer Research Communications, February 2022, American Association for Cancer Research (AACR)

    Laura Soucek

  8. Frequent mutations of FBXO11 highlight BCL6 as a therapeutic target in Burkitt lymphoma

    Article • Blood Advances, December 2021, American Society of Hematology

    Laura Soucek

  9. The long journey to bring a Myc inhibitor to the clinic

    Article • The Journal of Cell Biology, June 2021, Rockefeller University Press

    Laura Soucek

  10. Integrated requirement of non‐specific and sequence‐specific DNA binding in Myc‐driven transcription

    Article • The EMBO Journal, April 2021, Springer Science + Business Media

    Laura Soucek

  11. The Wnt signaling receptor Fzd9 is essential for Myc-driven tumorigenesis in pancreatic islets

    Article • Life Science Alliance, March 2021, Life Science Alliance, LLC

    Laura Soucek

  12. MYC inhibitors in multiple myeloma

    Article • January 2021, OAE Publishing

    Laura Soucek

  13. The Myc Gene

    Article • January 2021, Springer Science + Business Media

    Laura Soucek

  14. An “-omycs” Toolbox to Work with MYC

    Article • January 2021, Springer Science + Business Media

    Laura Soucek

  15. Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

    Article • Nature Genetics, January 2021, Springer Science + Business Media

    Laura Soucek

  16. Structural and Biophysical Insights into the Function of the Intrinsically Disordered Myc Oncoprotein

    Article • Cells, April 2020, MDPI AG

    Laura Soucek

  17. Blocking Myc to Treat Cancer: Reflecting on Two Decades of Omomyc

    Article • Cells, April 2020, MDPI AG

    Laura Soucek

  18. MYC Instructs and Maintains Pancreatic Adenocarcinoma Phenotype

    Article • Cancer Discovery, April 2020, American Association for Cancer Research (AACR)

    Laura Soucek

  19. MYC, MYCL, and MYCN as therapeutic targets in lung cancer

    Article • Expert Opinion on Therapeutic Targets, February 2020, Taylor & Francis

    Laura Soucek

  20. A spotlight on cancer researchers in Spain: new paradigms and disruptive ideas

    Article • Clinical & Translational Oncology, August 2019, Springer Science + Business Media

    Laura Soucek

  21. Editorial overview: Peptides in cancer

    Article • Current Opinion in Pharmacology, August 2019, Elsevier

    Laura Soucek

  22. Targeting Antitumoral Proteins to Breast Cancer by Local Administration of Functional Inclusion Bodies

    Article • Advanced Science, July 2019, Wiley

    Laura Soucek

  23. Finding MYCure

    Article • Molecular & Cellular Oncology, June 2019, Taylor & Francis

    Laura Soucek

  24. Intrinsic cell-penetrating activity propels Omomyc from proof of concept to viable anti-MYC therapy

    Article • Science Translational Medicine, March 2019, American Association for the Advancement of Science

    Laura Soucek

  25. BET inhibition is an effective approach against KRAS-driven PDAC and NSCLC

    Article • Oncotarget, April 2018, Impact Journals, LLC

    Laura Soucek

  26. Myc and Ras, the Bonnie and Clyde of immune evasion

    Article • Translational Cancer Research, April 2018, AME Publishing Company

    Laura Soucek

  27. Drugging the 'undruggable' cancer targets

    Article • Nature Reviews Cancer, June 2017, Springer Science + Business Media

    Laura Soucek

  28. Pancreatic cancer heterogeneity and response to Mek inhibition

    Article • Oncogene, June 2017, Springer Science + Business Media

    Laura Soucek

  29. Strategies to Inhibit Myc and Their Clinical Applicability

    Article • Frontiers in Cell and Developmental Biology, February 2017, Frontiers

    Laura Soucek

  30. Interrogating open issues in cancer precision medicine with patient-derived xenografts

    Article • Nature Reviews Cancer, January 2017, Springer Science + Business Media

    Laura Soucek

  31. Abstract 2923: Preclinical validation of Omomyc cell-penetrating peptides as a viable in vivo anti-Myc therapy

    Article • Cancer Research, July 2016, American Association for Cancer Research (AACR)

    Laura Soucek

  32. Ibrutinib repurposing: from B-cell malignancies to solid tumors

    Article • Oncoscience, June 2016, Impact Journals, LLC

    Laura Soucek

  33. Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

    Article • Carcinogenesis, June 2015, Oxford University Press (OUP)

    Dr Chiara Mondello, Dr Nicole Kleinstreuer, Dr GRAEME P WILLIAMS, Dr VALERIAN DORMOY, Professor Po Sing Leung, Colleen Curran, Laura Soucek

  34. The effect of environmental chemicals on the tumor microenvironment

    Article • Carcinogenesis, June 2015, Oxford University Press (OUP)

    Dr Chiara Mondello, Colleen Curran, Laura Soucek

  35. Tamoxifen Administration to Mice

    Article • Cold Spring Harbor Protocols, March 2015, Cold Spring Harbor Laboratory Press

    Laura Soucek

  36. Live or Die: Choice Mechanisms in Stressed Cells

    Article • Mediators of Inflammation, January 2015, Hindawi Publishing Corporation

    Laura Soucek

  37. The Myc Gene

    Article • January 2013, Springer Science + Business Media

    Laura Soucek

  38. The Myc World Within Reach

    Article • January 2013, Springer Science + Business Media

    Laura Soucek

  39. Tumor microenvironment: becoming sick of Myc

    Article • Cellular and Molecular Life Sciences, October 2011, Springer Science + Business Media

    Laura Soucek

  40. Endogenous Myc maintains the tumor microenvironment

    Article • Genes & Development, April 2011, Cold Spring Harbor Laboratory Press

    Laura Soucek

  41. The ups and downs of Myc biology

    Article • Current Opinion in Genetics & Development, February 2010, Elsevier

    Laura Soucek

  42. Myc—Is this the oncogene from Hell?

    Article • Cancer Cell, June 2002, Elsevier

    Laura Soucek

  43. Making decisions through Myc

    Article • FEBS Letters, February 2001, Wiley

    Laura Soucek