All Stories

  1. Cells with stemness features are generated from in vitro transformed human fibroblasts

    Article • Scientific Reports, September 2018, Springer Science + Business Media

    Dr Chiara Mondello

  2. Snail levels control the migration mechanism of mesenchymal tumor cells

    Article • Oncology Letters, May 2016, Spandidos Publications

    Dr Chiara Mondello

  3. A comprehensive strategy for the analysis of acoustic compressibility and optical deformability on single cells

    Article • Scientific Reports, April 2016, Nature

    Dr Chiara Mondello

  4. Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

    Article • Carcinogenesis, June 2015, Oxford University Press (OUP)

    Dr Chiara Mondello, Dr Nicole Kleinstreuer, Dr GRAEME P WILLIAMS, Dr VALERIAN DORMOY, Professor Po Sing Leung, Colleen Curran, Laura Soucek

  5. Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression

    Article • Carcinogenesis, June 2015, Oxford University Press (OUP)

    Dr Chiara Mondello

  6. The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling

    Article • Carcinogenesis, June 2015, Oxford University Press (OUP)

    Dr Chiara Mondello

  7. The impact of low-dose carcinogens and environmental disruptors on tissue invasion and metastasis

    Article • Carcinogenesis, June 2015, Oxford University Press (OUP)

    Dr Chiara Mondello

  8. The effect of environmental chemicals on the tumor microenvironment

    Article • Carcinogenesis, June 2015, Oxford University Press (OUP)

    Dr Chiara Mondello, Colleen Curran, Laura Soucek

  9. Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?

    Article • Carcinogenesis, June 2015, Oxford University Press (OUP)

    Dr Chiara Mondello, Dr GRAEME P WILLIAMS

  10. Disruptive environmental chemicals and cellular mechanisms that confer resistance to cell death

    Article • Carcinogenesis, June 2015, Oxford University Press (OUP)

    Dr Chiara Mondello, Professor Po Sing Leung

  11. Disruptive chemicals, senescence and immortality

    Article • Carcinogenesis, June 2015, Oxford University Press (OUP)

    Dr Chiara Mondello

  12. Causes of genome instability: the effect of low dose chemical exposures in modern society

    Article • Carcinogenesis, June 2015, Oxford University Press (OUP)

    Dr Chiara Mondello

  13. Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: focus on the cancer hallmark of tumor angiogenesis

    Article • Carcinogenesis, June 2015, Oxford University Press (OUP)

    Dr Chiara Mondello, Dr Nicole Kleinstreuer, Dr VALERIAN DORMOY

  14. Chemical compounds from anthropogenic environment and immune evasion mechanisms: potential interactions

    Article • Carcinogenesis, May 2015, Oxford University Press (OUP)

    Dr Chiara Mondello

  15. Sorting on the basis of deformability of single cells in a femtosecond laser fabricated optofluidic device

    Article • March 2015, SPIE

    Dr Chiara Mondello

  16. A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds

    Article • Nucleic Acids Research, January 2015, Oxford University Press (OUP)

    Dr Chiara Mondello

  17. An integrated optofluidic device for single-cell sorting driven by mechanical properties

    Article • Lab on a Chip, January 2015, Royal Society of Chemistry

    Paolo Minzioni, Dr Chiara Mondello

  18. An optofluidic constriction chip for monitoring metastatic potential and drug response of cancer cells

    Article • Integrative Biology, January 2015, Oxford University Press (OUP)

    Dr Chiara Mondello

  19. Stable Cellular Senescence Is Associated with Persistent DDR Activation

    Article • PLoS ONE, October 2014, PLOS

    Dr Chiara Mondello

  20. Super-telomeres in transformed human fibroblasts

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, August 2013, Elsevier

    Dr Chiara Mondello

  21. Cellular immortalization and neoplastic transformation

    Article • Cell Cycle, June 2013, Taylor & Francis

    Dr Chiara Mondello

  22. An integrated fluorescence activated cell sorter fabricated by femtosecond laser micromachining

    Article • MATEC Web of Conferences, January 2013, EDP Sciences

    Dr Chiara Mondello

  23. The catalytic and the RNA subunits of human telomerase are required to immortalize equid primary fibroblasts

    Article • Chromosoma, July 2012, Springer Science + Business Media

    Dr Chiara Mondello

  24. Cross-Analysis of Gene and miRNA Genome-Wide Expression Profiles in Human Fibroblasts at Different Stages of Transformation

    Article • OMICS A Journal of Integrative Biology, February 2012, Mary Ann Liebert Inc

    Dr Chiara Mondello

  25. Optofluidic integrated cell sorter fabricated by femtosecond lasers

    Article • Lab on a Chip, January 2012, Royal Society of Chemistry

    Paolo Minzioni, Dr Chiara Mondello

  26. Telomere-independent functions of telomerase in nuclei, cytoplasm, and mitochondria

    Article • Frontiers in Oncology, January 2012, Frontiers

    Dr Chiara Mondello

  27. Relocalization of cell adhesion molecules during neoplastic transformation of human fibroblasts

    Article • International Journal of Oncology, July 2011, Spandidos Publications

    Dr Chiara Mondello

  28. Drug Treatment of Cancer Cell Lines: A Way to Select for Cancer Stem Cells?

    Article • Cancers, March 2011, MDPI AG

    Dr Chiara Mondello

  29. Gene amplification in human cells knocked down for RAD54

    Article • Genome Integrity, January 2011, Springer Science + Business Media

    Dr Chiara Mondello

  30. Reduced Expression of the ROCK Inhibitor Rnd3 Is Associated with Increased Invasiveness and Metastatic Potential in Mesenchymal Tumor Cells

    Article • PLoS ONE, November 2010, PLOS

    Dr Chiara Mondello

  31. Gene amplification, radiation sensitivity and DNA double-strand breaks

    Article • Mutation Research/Reviews in Mutation Research, April 2010, Elsevier

    Dr Chiara Mondello

  32. Apoptosis: A Way to Maintain Healthy Individuals

    Article • December 2009, Springer Science + Business Media

    Dr Chiara Mondello

  33. Enhanced gene amplification in human cells knocked down for DNA-PKcs

    Article • DNA Repair, January 2009, Elsevier

    Dr Chiara Mondello

  34. Replication protein A and proliferating cell nuclear antigen coordinate DNA polymerase selection in 8-oxo-guanine repair

    Article • Proceedings of the National Academy of Sciences, December 2008, Proceedings of the National Academy of Sciences

    Dr Chiara Mondello

  35. Telomerase: cellular immortalization and neoplastic transformation. Multiple functions of a multifaceted complex

    Article • Cytogenetic and Genome Research, January 2008, Karger Publishers

    Dr Chiara Mondello

  36. Transfer of a Human Chromosomal Vector from a Hamster Cell Line to a Mouse Embryonic Stem Cell Line

    Article • Stem Cells, October 2007, Wiley

    Dr Chiara Mondello

  37. Contribution of telomerase RNA retrotranscription to DNA double-strand break repair during mammalian genome evolution

    Article • Genome Biology, January 2007, Springer Science + Business Media

    Dr Chiara Mondello

  38. Oxidative Stress Response in Telomerase-Immortalized Fibroblasts from a Centenarian

    Article • Annals of the New York Academy of Sciences, December 2006, Wiley

    Dr Chiara Mondello

  39. Inhibition of gene amplification in telomerase deficient immortalized mouse embryonic fibroblasts

    Article • Carcinogenesis, August 2006, Oxford University Press (OUP)

    Dr Chiara Mondello

  40. Stepwise Neoplastic Transformation of a Telomerase Immortalized Fibroblast Cell Line

    Article • Cancer Research, December 2005, American Association for Cancer Research (AACR)

    Dr Chiara Mondello

  41. New mammalian cellular systems to study mutations introduced at the break site by non-homologous end-joining

    Article • DNA Repair, May 2005, Elsevier

    Dr Chiara Mondello

  42. Insertion of Telomeric Repeats at Intrachromosomal Break Sites During Primate Evolution

    Article • Genome Research, September 2004, Cold Spring Harbor Laboratory Press

    Dr Chiara Mondello

  43. Telomeres, telomerase, and apoptosis

    Article • Biochemistry and Cell Biology, August 2004, Canadian Science Publishing

    Dr Chiara Mondello

  44. Interstitial telomeric repeats are not preferentially involved in radiation-induced chromosome aberrations in human cells

    Article • Cytogenetic and Genome Research, January 2004, Karger Publishers

    Dr Chiara Mondello

  45. Chromosomal end-to-end fusions in immortalized mouse embryonic fibroblasts deficient in the DNA-dependent protein kinase catalytic subunit

    Article • Cancer Letters, January 2004, Elsevier

    Dr Chiara Mondello

  46. Karyotype instability and anchorage-independent growth in telomerase-immortalized fibroblasts from two centenarian individuals

    Article • Biochemical and Biophysical Research Communications, September 2003, Elsevier

    Dr Chiara Mondello

  47. γ-Ray and hydrogen peroxide induction of gene amplification in hamster cells deficient in DNA double strand break repair

    Article • DNA Repair, June 2002, Elsevier

    Dr Chiara Mondello

  48. Molecular organization of internal telomeric sequences in Chinese hamster chromosomes

    Article • Gene, January 2002, Elsevier

    Dr Chiara Mondello

  49. Instability of Interstitial Telomeric Sequences in the Human Genome

    Article • Genomics, September 2000, Elsevier

    Dr Chiara Mondello

  50. Late onset of CAD gene amplification in unamplified PALA resistant Chinese hamster mutants

    Article • Cancer Letters, March 2000, Elsevier

    Dr Chiara Mondello

  51. Occurrence and expansion of trisomy 7 in a fibroblast strain from a centenarian individual☆

    Article • Experimental Gerontology, August 1999, Elsevier

    Dr Chiara Mondello

  52. Telomere Length in Fibroblasts and Blood Cells from Healthy Centenarians

    Article • Experimental Cell Research, April 1999, Elsevier

    Dr Chiara Mondello

  53. Telomeres

    Article • January 1998, Elsevier

    Dr Chiara Mondello

  54. Chromosomal Instability and Telomere Length Variations during the Life Span of Human Fibroblast Clones

    Article • Experimental Cell Research, November 1997, Elsevier

    Dr Chiara Mondello

  55. Telomeric fusions in cultured human fibroblasts as a source of genomic instability

    Article • Cancer Genetics and Cytogenetics, June 1997, Elsevier

    Dr Chiara Mondello

  56. Condensation anomalies and exclusion in micronuclei of rearranged chromosomes in human fibroblasts cultured in vitro

    Article • Chromosoma, November 1995, Springer Science + Business Media

    Dr Chiara Mondello

  57. Gene amplification in Chinese hamster DNA repair deficient mutants

    Article • Mutation Research Letters, February 1995, Elsevier

    Dr Chiara Mondello

  58. Structural instability of a transmissible end-to-end dicentric chromosome in a xeroderma pigmentosum fibroblast clone

    Article • Cancer Genetics and Cytogenetics, January 1995, Elsevier

    Dr Chiara Mondello

  59. Molecular analysis of the XP-D gene in Italian families with patients affected by trichothiodystrophy and xeroderma pigmentosum group D

    Article • Mutation Research/DNA Repair, March 1994, Elsevier

    Dr Chiara Mondello

  60. Loss of histone H2AX increases sensitivity of immortalized mouse fibroblasts to the topoisomerase II inhibitor etoposide

    Article • International Journal of Oncology, January 1992, Spandidos Publications

    Dr Chiara Mondello

  61. Analysis of methylation of a human X located gene which escapes X inactivation

    Article • Nucleic Acids Research, January 1988, Oxford University Press (OUP)

    Dr Chiara Mondello

  62. Cellular and genetic studies in three UV-sensitive Chinese hamster mutants

    Article • Cytotechnology, October 1987, Springer Science + Business Media

    Dr Chiara Mondello

  63. Sensitivity to DNA-damaging agents and mutation induction by UV light in UV-sensitive CHO cells

    Article • Mutation Research Letters, June 1986, Elsevier

    Dr Chiara Mondello

  64. X-linked ichthyosis, due to steroid sulphatase deficiency, associated with Kallmann syndrome (hypogonadotropic hypogonadism and anosmia): linkage relationships with Xg and cloned DNA sequences from the distal short arm of the X chromosome

    Article • Human Genetics, March 1986, Springer Science + Business Media

    Dr Chiara Mondello

  65. Homologous expressed genes in the human sex chromosome pairing region

    Article • Nature, October 1985, Nature

    Dr Chiara Mondello

  66. Methylation and expression of a housekeeping gene

    Article • Trends in Genetics, January 1985, Elsevier

    Dr Chiara Mondello

  67. Chromosomal effects of methotrexate on cultured human lymphocytes

    Article • Mutation Research Letters, February 1984, Elsevier

    Dr Chiara Mondello

  68. Aphidicolin does not inhibit the repair synthesis of mitotic chromosomes

    Article • Biochemical and Biophysical Research Communications, April 1981, Elsevier

    Dr Chiara Mondello