All Stories

  1. Induction of human trophoblast stem-like cells from primed pluripotent stem cells
  2. The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer
  3. Conserved dual-mode gene regulation programs in higher eukaryotes
  4. Context-dependent roles of YAP/TAZ in stem cell fates and cancer
  5. Mechanobiological conditioning of mesenchymal stem cells for enhanced vascular regeneration
  6. Super-enhancer-guided mapping of regulatory networks controlling mouse trophoblast stem cells
  7. Systematic Discovery of Endogenous Human Ribonucleoprotein Complexes
  8. TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory Network
  9. Yap1 safeguards mouse embryonic stem cells from excessive apoptosis during differentiation
  10. miRNA-mediated TUSC3 deficiency enhances UPR and ERAD to promote metastatic potential of NSCLC
  11. Tumor penetrating peptides inhibiting MYC as a potent targeted therapeutic strategy for triple-negative breast cancers
  12. Homeodomain Proteins Directly Regulate ATM Kinase Activity
  13. Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a
  14. Implications of CpG islands on chromosomal architectures and modes of global gene regulation
  15. Fosl1 overexpression directly activates trophoblast-specific gene expression programs in embryonic stem cells
  16. ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors
  17. Mechanisms of transcription factor-mediated direct reprogramming of mouse embryonic stem cells to trophoblast stem-like cells
  18. Ethylene induces combinatorial effects of histone H3 acetylation in gene expression in Arabidopsis
  19. Fbxl19 recruitment to CpG islands is required for Rnf20-mediated H2B mono-ubiquitination
  20. ARID3A is required for mammalian placenta development
  21. BMI1–UBR5 axis regulates transcriptional repression at damaged chromatin
  22. Pathogen Infection and MORC Proteins Affect Chromatin Accessibility of Transposable Elements and Expression of Their Proximal Genes in Arabidopsis
  23. Yap1 is dispensable for self‐renewal but required for proper differentiation of mouse embryonic stem ( ES ) cells
  24. Serine/Threonine Kinase MLK4 Determines Mesenchymal Identity in Glioma Stem Cells in an NF-κB-dependent Manner
  25. The Pluripotency Factor NANOG Binds to GLI Proteins and Represses Hedgehog-mediated Transcription
  26. An Immunofluorescence-Assisted Microfluidic Single Cell Quantitative Reverse Transcription Polymerase Chain Reaction Analysis of Tumour Cells Separated from Blood
  27. Tgif1 Counterbalances the Activity of Core Pluripotency Factors in Mouse Embryonic Stem Cells
  28. PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells
  29. CpG island-mediated global gene regulatory modes in mouse embryonic stem cells
  30. Arid3a is essential to execution of the first cell fate decision via direct embryonic and extraembryonic transcriptional regulation
  31. Global Transcriptional Profiling Reveals Distinct Functions of Thymic Stromal Subsets and Age-Related Changes during Thymic Involution
  32. Multi-layered global gene regulation in mouse embryonic stem cells
  33. Staufen1-mediated mRNA decay induces Requiem mRNA decay through binding of Staufen1 to the Requiem 3'UTR
  34. Distinct and Combinatorial Functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in Mouse Embryonic Stem Cell Identity
  35. Splicing factor SRSF3 represses the translation of programmed cell death 4 mRNA by associating with the 5′-UTR region
  36. Developmental differences in IFN signaling affect GATA1s-induced megakaryocyte hyperproliferation
  37. ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients
  38. Surfactant Protein–C Chromatin-Bound Green Fluorescence Protein Reporter Mice Reveal Heterogeneity of Surfactant Protein C–Expressing Lung Cells
  39. Transcription Elongation Factor Tcea3 Regulates the Pluripotent Differentiation Potential of Mouse Embryonic Stem Cells Via the Lefty1 ‐Nodal‐Smad2 Pathway
  40. The Response of the Prostate to Circulating Cholesterol: Activating Transcription Factor 3 (ATF3) as a Prominent Node in a Cholesterol-Sensing Network
  41. Role of ZBP-89 in human globin gene regulation and erythroid differentiation
  42. Embryonic stem cell-specific signatures in cancer: insights into genomic regulatory networks and implications for medicine
  43. A Myc Network Accounts for Similarities between Embryonic Stem and Cancer Cell Transcription Programs
  44. Sumoylation Regulates Interaction of FOG1 with C-terminal-binding Protein (CTBP)
  45. Epigenetic memory in induced pluripotent stem cells
  46. TIF1γ Controls Erythroid Cell Fate by Regulating Transcription Elongation
  47. Systematic tracking of cell fate changes
  48. DNA Methyltransferase 1 Is Essential for and Uniquely Regulates Hematopoietic Stem and Progenitor Cells
  49. A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal
  50. Use of in vivo biotinylation to study protein–protein and protein–DNA interactions in mouse embryonic stem cells
  51. EZH1 Mediates Methylation on Histone H3 Lysine 27 and Complements EZH2 in Maintaining Stem Cell Identity and Executing Pluripotency
  52. Global Identification of Myc Target Genes Reveals Its Direct Role in Mitochondrial Biogenesis and Its E-Box Usage In Vivo
  53. An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells
  54. The Transcriptional Network Controlling Pluripotency in ES Cells
  55. Epigenetic Regulation of Hematopoietic Differentiation by Gfi-1 and Gfi-1b Is Mediated by the Cofactors CoREST and LSD1
  56. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
  57. Mapping the chromosomal targets of STAT1 by Sequence Tag Analysis of Genomic Enrichment (STAGE)
  58. FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) isolates active regulatory elements from human chromatin
  59. Identifying Chromosomal Targets of DNA‐Binding Proteins by Sequence Tag Analysis of Genomic Enrichment (STAGE)
  60. Mapping DNA-protein interactions in large genomes by sequence tag analysis of genomic enrichment
  61. Global Role of TATA Box-Binding Protein Recruitment to Promoters in Mediating Gene Expression Profiles