All Stories

  1. Standardized pipeline for establishing, expanding, and differentiating airway and alveolar organoids from human BAL fluid

    Article • October 2025, Cold Spring Harbor Laboratory Press

    Carla Kim

  2. Early-stage lung cancer is driven by a transitional cell state dependent on a KRAS-ITGA3-SRC axis

    Article • The EMBO Journal, May 2024, Springer Science + Business Media

    Carla Kim

  3. Early-stage lung adenocarcinoma is driven by an injury-associated, plastic cell state dependent on a KRAS-ITGA3-SRC axis

    Article • March 2024, Cold Spring Harbor Laboratory Press

    Carla Kim

  4. Organoid modeling reveals the tumorigenic potential of the alveolar progenitor cell state

    Article • March 2023, Springer Science + Business Media

    Carla Kim

  5. Comparison of Transplantation of Lung Organoid Cell Types: One Size Does Not Fit All

    Article • American Journal of Respiratory Cell and Molecular Biology, March 2022, American Thoracic Society

    Carla Kim

  6. Alveolar progenitor cells and the origin of lung cancer

    Article • Journal of Internal Medicine, December 2020, Wiley

    Carla Kim

  7. An airway organoid is forever

    Article • The EMBO Journal, February 2019, EMBO

    Carla Kim

  8. E-Cadherin Loss Accelerates Tumor Progression and Metastasis in a Mouse Model of Lung Adenocarcinoma

    Article • American Journal of Respiratory Cell and Molecular Biology, August 2018, American Thoracic Society

    Juliana Barrios, Carla Kim

  9. A New “Age”r for Lung Research Arrives: Genetic Targeting of Alveolar Type 1 Epithelial Cells

    Article • American Journal of Respiratory Cell and Molecular Biology, July 2018, American Thoracic Society

    Carla Kim

  10. Amnion Epithelial Cell-Derived Exosomes Restrict Lung Injury and Enhance Endogenous Lung Repair

    Article • Stem Cells Translational Medicine, January 2018, Wiley

    Carla Kim

  11. The Epithelial Sodium Channel Is a Modifier of the Long-Term Nonprogressive Phenotype Associated with F508del CFTR Mutations

    Article • American Journal of Respiratory Cell and Molecular Biology, December 2017, American Thoracic Society

    Carla Kim

  12. Human amnion cells reverse acute and chronic pulmonary damage in experimental neonatal lung injury

    Article • Stem Cell Research & Therapy, November 2017, Springer Science + Business Media

    Carla Kim

  13. “Intersections of lung progenitor cells, lung disease and lung cancer.” Carla F. Kim. Eur Respir Rev 2017; 26: 170054.

    Article • European Respiratory Review, October 2017, European Respiratory Society (ERS)

    Carla Kim

  14. Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6

    Article • Cell, September 2017, Elsevier

    Carla Kim

  15. Intersections of lung progenitor cells, lung disease and lung cancer

    Article • European Respiratory Review, June 2017, European Respiratory Society (ERS)

    Carla Kim

  16. Don’t Stop Re-healin’! Cancer as an Ongoing Stem Cell Affair

    Article • Cell, May 2017, Elsevier

    Carla Kim

  17. Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2

    Article • Nature Communications, April 2017, Springer Science + Business Media

    Carla Kim

  18. Oncogenic Deregulation of EZH2 as an Opportunity for Targeted Therapy in Lung Cancer

    Article • Cancer Discovery, June 2016, American Association for Cancer Research (AACR)

    Carla Kim

  19. Lung Cancer Stem Cells

    Article • January 2016, Elsevier

    Carla Kim

  20. Tracing the potential of lung progenitors

    Article • Nature Biotechnology, February 2015, Springer Science + Business Media

    Carla Kim

  21. EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors

    Article • Nature, January 2015, Springer Science + Business Media

    Carla Kim

  22. Mesenchymal progenitor panoply

    Article • Science, November 2014, American Association for the Advancement of Science

    Carla Kim

  23. Non-small-cell lung cancers: a heterogeneous set of diseases

    Article • Nature Reviews Cancer, August 2014, Springer Science + Business Media

    Carla Kim

  24. Tumor-propagating cells and Yap/Taz activity contribute to lung tumor progression and metastasis

    Article • The EMBO Journal, July 2014, EMBO

    Juliana Barrios, Carla Kim, Darcy Wagner

  25. Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis

    Article • Proceedings of the National Academy of Sciences, June 2014, Proceedings of the National Academy of Sciences

    Juliana Barrios, Carla Kim

  26. Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated PD-L1 Expression

    Article • Cancer Cell, May 2014, Elsevier

    Carla Kim

  27. Diverse cells at the origin of lung adenocarcinoma

    Article • Proceedings of the National Academy of Sciences, March 2014, Proceedings of the National Academy of Sciences

    Carla Kim

  28. Bone Marrow-Derived Multipotent Stromal Cells Attenuate Inflammation in Obliterative Airway Disease in Mouse Tracheal Allografts

    Article • Stem Cells International, January 2014, Hindawi Publishing Corporation

    Carla Kim

  29. Lung Stem Cell Differentiation in Mice Directed by Endothelial Cells via a BMP4-NFATc1-Thrombospondin-1 Axis

    Article • Cell, January 2014, Elsevier

    Carla Kim

  30. Lung Stem and Progenitor Cells in Tissue Homeostasis and Disease

    Article • January 2014, Elsevier

    Carla Kim

  31. A genetic screen identifies an LKB1–MARK signalling axis controlling the Hippo–YAP pathway

    Article • Nature Cell Biology, December 2013, Springer Science + Business Media

    Carla Kim

  32. Thrombospondin-1 mediates oncogenic Ras–induced senescence in premalignant lung tumors

    Article • Journal of Clinical Investigation, September 2013, American Society for Clinical Investigation

    Carla Kim

  33. Surfactant Protein–C Chromatin-Bound Green Fluorescence Protein Reporter Mice Reveal Heterogeneity of Surfactant Protein C–Expressing Lung Cells

    Article • American Journal of Respiratory Cell and Molecular Biology, March 2013, American Thoracic Society

    Juliana Barrios, Carla Kim, Jonghwan Kim

  34. The bed and the bugs: Interactions between the tumor microenvironment and cancer stem cells

    Article • Seminars in Cancer Biology, October 2012, Elsevier

    Carla Kim

  35. Airway Epithelial Progenitors Are Region Specific and Show Differential Responses to Bleomycin‐Induced Lung Injury

    Article • Stem Cells, August 2012, Oxford University Press (OUP)

    Professor Dianhua Jiang, Carla Kim

  36. Bronchioalveolar stem cells increase after mesenchymal stromal cell treatment in a mouse model of bronchopulmonary dysplasia

    Article • AJP Lung Cellular and Molecular Physiology, May 2012, American Physiological Society

    Carla Kim

  37. Direct Recruitment of Polycomb Repressive Complex 1 to Chromatin by Core Binding Transcription Factors

    Article • Molecular Cell, February 2012, Elsevier

    Carla Kim

  38. Isolation and Characterization of Distal Lung Progenitor Cells

    Article • January 2012, Springer Science + Business Media

    Carla Kim

  39. Lung Stem Cell Self-Renewal Relies on BMI1-Dependent Control of Expression at Imprinted Loci

    Article • Cell Stem Cell, September 2011, Elsevier

    Dr Christoph Bock, Carla Kim

  40. Primary Tumor Genotype Is an Important Determinant in Identification of Lung Cancer Propagating Cells

    Article • Cell Stem Cell, July 2010, Elsevier

    Carla Kim

  41. Integrative Genomic and Proteomic Analyses Identify Targets for Lkb1-Deficient Metastatic Lung Tumors

    Article • Cancer Cell, June 2010, Elsevier

    Carla Kim

  42. Matrix modulation of compensatory lung regrowth and progenitor cell proliferation in mice

    Article • AJP Lung Cellular and Molecular Physiology, February 2010, American Physiological Society

    Carla Kim

  43. p53 Controls Radiation-Induced Gastrointestinal Syndrome in Mice Independent of Apoptosis

    Article • Science, December 2009, American Association for the Advancement of Science

    Carla Kim, Osamu Takeuchi

  44. Separating Stem Cells by Flow Cytometry: Reducing Variability for Solid Tissues

    Article • Cell Stem Cell, December 2009, Elsevier

    Carla Kim

  45. Commentary: Sca-1 and Cells of the Lung: A matter of Different Sorts

    Article • Stem Cells, March 2009, Wiley

    Carla Kim

  46. Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion

    Article • Proceedings of the National Academy of Sciences, August 2008, Proceedings of the National Academy of Sciences

    Carla Kim

  47. Cancer and Stem Cell Biology: How Tightly Intertwined?

    Article • Cell Stem Cell, August 2008, Elsevier

    Carla Kim

  48. Stem Cells and Cell Therapies in Lung Biology and Lung Diseases

    Article • Proceedings of the American Thoracic Society, July 2008, American Thoracic Society

    Carla Kim

  49. Cellular kinetics and modeling of bronchioalveolar stem cell response during lung regeneration

    Article • AJP Lung Cellular and Molecular Physiology, June 2008, American Physiological Society

    Carla Kim

  50. Phosphatidylinositol 3-Kinase Mediates Bronchioalveolar Stem Cell Expansion in Mouse Models of Oncogenic K-ras-Induced Lung Cancer

    Article • PLOS One, May 2008, PLOS

    Carla Kim

  51. Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer

    Article • Carcinogenesis, February 2008, Oxford University Press (OUP)

    Carla Kim

  52. Stem Cell Biology in the Lung and Lung Cancers: Using Pulmonary Context and Classic Approaches

    Article • Cold Spring Harbor Symposia on Quantitative Biology, January 2008, Cold Spring Harbor Laboratory Press

    Carla Kim

  53. Paving the road for lung stem cell biology: bronchioalveolar stem cells and other putative distal lung stem cells

    Article • AJP Lung Cellular and Molecular Physiology, November 2007, American Physiological Society

    Carla Kim

  54. Requirement for Rac1 in a K-ras Induced Lung Cancer in the Mouse

    Article • Cancer Research, September 2007, American Association for Cancer Research (AACR)

    Carla Kim

  55. Duality of p27Kip1 function in tumorigenesis

    Article • Genes & Development, July 2007, Cold Spring Harbor Laboratory Press

    Carla Kim

  56. MAPK-ing Out the Pathways in Lung Stem Cell Regulation

    Article • Cell Stem Cell, June 2007, Elsevier

    Carla Kim

  57. E2f4 is required for normal development of the airway epithelium

    Article • Developmental Biology, May 2007, Elsevier

    Carla Kim

  58. Advancing the field of lung stem cell biology

    Article • Frontiers in Bioscience, January 2007, Frontiers in Bioscience

    Carla Kim

  59. The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor

    Article • Genes & Development, December 2005, Cold Spring Harbor Laboratory Press

    Carla Kim

  60. K-ras activation generates an inflammatory response in lung tumors

    Article • Oncogene, November 2005, Springer Science + Business Media

    Carla Kim

  61. Use of gene expression profiling to direct in vivo molecular imaging of lung cancer

    Article • Proceedings of the National Academy of Sciences, September 2005, Proceedings of the National Academy of Sciences

    Carla Kim

  62. Identification of Bronchioalveolar Stem Cells in Normal Lung and Lung Cancer

    Article • Cell, June 2005, Elsevier

    Carla Kim

  63. Mouse Models of Human Non-Small-Cell Lung Cancer: Raising the Bar

    Article • Cold Spring Harbor Symposia on Quantitative Biology, January 2005, Cold Spring Harbor Laboratory Press

    Carla Kim

  64. Cancer predisposition and hematopoietic failure in Rad50S/S mice

    Article • Genes & Development, September 2002, Cold Spring Harbor Laboratory Press

    Carla Kim

  65. Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

    Article • Proceedings of the National Academy of Sciences, June 1999, Proceedings of the National Academy of Sciences

    Carla Kim