Professor Jonathan Luke Heeney – Kudos: Growing the influence of research

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Increased, Durable B-Cell and ADCC Responses Associated with T-Helper Cell Responses to HIV-1 Envelope in Macaques Vaccinated with gp140 Occluded at the CD4 Receptor Binding Site

Article • Journal of Virology, July 2017, ASM Journals

Willy Bogers, Professor Jonathan Luke Heeney
Plagues

Article • January 2017, Cambridge University Press

Professor Jonathan Luke Heeney
Hidden reservoirs

Article • Nature, November 2015, Springer Science + Business Media

Professor Jonathan Luke Heeney
Simian Immunodeficiency Virus Infection of Chimpanzees (Pan troglodytes) Shares Features of Both Pathogenic and Non-pathogenic Lentiviral Infections

Article • PLoS Pathogens, September 2015, PLOS

Professor Jonathan Luke Heeney
Host Subtraction, Filtering and Assembly Validations for Novel Viral Discovery Using Next Generation Sequencing Data

Article • PLoS ONE, June 2015, PLOS

Professor Jonathan Luke Heeney
Head-to-Head Comparison of Poxvirus NYVAC and ALVAC Vectors Expressing Identical HIV-1 Clade C Immunogens in Prime-Boost Combination with Env Protein in Nonhuman Primates

Article • Journal of Virology, June 2015, ASM Journals

Professor Jonathan Luke Heeney
Synthetic long peptide booster immunization in rhesus macaques primed with replication-competent NYVAC-C-KC induces a balanced CD4/CD8 T-cell and antibody response against the conserved regions of HIV-1

Article • Journal of General Virology, June 2015, Society for General Microbiology

Professor Jonathan Luke Heeney
Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance

Article • Nature Communications, May 2015, Springer Science + Business Media

Professor Jonathan Luke Heeney
Defense-in-depth by mucosally administered anti-HIV dimeric IgA2 and systemic IgG1 mAbs: Complete protection of rhesus monkeys from mucosal SHIV challenge

Article • Vaccine, April 2015, Elsevier

Professor Jonathan Luke Heeney
A helminth-mediated viral awakening

Article • Trends in Immunology, October 2014, Elsevier

Professor Jonathan Luke Heeney
Potent Immune Responses in Rhesus Macaques Induced by Nonviral Delivery of a Self-amplifying RNA Vaccine Expressing HIV Type 1 Envelope With a Cationic Nanoemulsion

Article • The Journal of Infectious Diseases, September 2014, Oxford University Press (OUP)

Professor Jonathan Luke Heeney
Development and immunological assessment of VLP-based immunogens exposing the membrane-proximal region of the HIV-1 gp41 protein

Article • Journal of Biomedical Science, August 2014, Springer Science + Business Media

Professor Jonathan Luke Heeney
A Fusion Intermediate gp41 Immunogen Elicits Neutralizing Antibodies to HIV-1

Article • Journal of Biological Chemistry, August 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

Professor Jonathan Luke Heeney
Full-Length Genome Analyses of Two New Simian Immunodeficiency Virus (SIV) Strains from Mustached Monkeys (C. Cephus) in Gabon Illustrate a Complex Evolutionary History among the SIVmus/mon/gsn Lineage

Article • Viruses, July 2014, MDPI AG

Professor Jonathan Luke Heeney
Host factors determine differential disease progression after infection with nef-deleted simian immunodeficiency virus

Article • Journal of General Virology, June 2014, Society for General Microbiology

Professor Jonathan Luke Heeney
Strong Vaccine-Induced CD8 T-Cell Responses Have Cytolytic Function in a Chimpanzee Clearing HCV Infection

Article • PLoS ONE, April 2014, PLOS

Professor Jonathan Luke Heeney
Simian Immunodeficiency Virus Infection of Chimpanzees (Pan troglodytes)

Article • January 2014, Elsevier

Professor Jonathan Luke Heeney
Pathology caused by persistent murine norovirus infection

Article • Journal of General Virology, November 2013, Society for General Microbiology

Professor Jonathan Luke Heeney
Loss of memory CD4+ T-cells in semi-wild mandrills (Mandrillus sphinx) naturally infected with species-specific simian immunodeficiency virus SIVmnd-1

Article • Journal of General Virology, November 2013, Society for General Microbiology

Professor Jonathan Luke Heeney
In Vitro Neutralization of Low Dose Inocula at Physiological Concentrations of a Monoclonal Antibody Which Protects Macaques against SHIV Challenge

Article • PLoS ONE, August 2013, PLOS

Professor Jonathan Luke Heeney
Genetic Imprint of Vaccination on Simian/Human Immunodeficiency Virus Type 1 Transmitted Viral Genomes in Rhesus Macaques

Article • PLoS ONE, August 2013, PLOS

Professor Jonathan Luke Heeney
Canine hepacivirus is not associated with chronic liver disease in dogs

Article • August 2013, Wiley

Professor Jonathan Luke Heeney
what viruses do West African fruit bats carry?

Article • Virology, July 2013, Elsevier

James Wood, Dr Pablo R Murcia, Dr Richard M Leggett, Professor Jonathan Luke Heeney
Anti-HIV IgA isotypes

Article • AIDS, June 2013, Wolters Kluwer Health

Professor Jonathan Luke Heeney
DLA Class II Alleles and Haplotypes Are Associated with Risk for and Protection from Chronic Hepatitis in the English Springer Spaniel

Article • PLoS ONE, August 2012, PLOS

Professor Jonathan Luke Heeney
Mixed Adjuvant Formulations Reveal a New Combination That Elicit Antibody Response Comparable to Freund's Adjuvants

Article • PLoS ONE, April 2012, PLOS

Professor Jonathan Luke Heeney
Use of a polyanionic carbomer, Carbopol971P, in combination with MF59, improves antibody responses to HIV-1 envelope glycoprotein

Article • Vaccine, April 2012, Elsevier

Professor Jonathan Luke Heeney
Immunization with apoptotic pseudovirus transduced cells induces both cellular and humoral responses: A proof of concept study in macaques

Article • Vaccine, March 2012, Elsevier

Professor Jonathan Luke Heeney
Control of Simian Immunodeficiency Virus SIVmnd-1 RNA Plasma Viremia after Coinfection or Superinfection with SIVmnd-1 in SIVmnd-2-Infected Mandrills and Vice Versa

Article • Journal of Virology, January 2012, ASM Journals

Professor Jonathan Luke Heeney
Perspectives in HIV Vaccine Development: What we have Learned and how we Proceed Forward

Article • Journal of AIDS & Clinical Research, January 2012, OMICS Publishing Group

Professor Jonathan Luke Heeney
Protection in Macaques Immunized with HIV-1 Candidate Vaccines Can Be Predicted Using the Kinetics of Their Neutralizing Antibodies

Article • PLoS ONE, December 2011, PLOS

Professor Jonathan Luke Heeney
A Viral Discovery Methodology for Clinical Biopsy Samples Utilising Massively Parallel Next Generation Sequencing

Article • PLoS ONE, December 2011, PLOS

Professor Jonathan Luke Heeney
Nef Decreases HIV-1 Sensitivity to Neutralizing Antibodies that Target the Membrane-proximal External Region of TMgp41

Article • PLoS Pathogens, December 2011, PLOS

Professor Jonathan Luke Heeney
Norovirus Regulation of the Innate Immune Response and Apoptosis Occurs via the Product of the Alternative Open Reading Frame 4

Article • PLoS Pathogens, December 2011, PLOS

Professor Jonathan Luke Heeney
Clearance of Genotype 1b Hepatitis C Virus in Chimpanzees in the Presence of Vaccine-Induced E1-Neutralizing Antibodies

Article • The Journal of Infectious Diseases, September 2011, Oxford University Press (OUP)

Professor Jonathan Luke Heeney
Herpesvirus saimiri infection of rhesus macaques: A model for acute rhadinovirus-induced t-cell transformation and oncogenesis

Article • September 2011, Wiley

Professor Jonathan Luke Heeney
Molecular Evolution Analysis of the Human Immunodeficiency Virus Type 1 Envelope in Simian/Human Immunodeficiency Virus-Infected Macaques: Implications for Challenge Dose Selection

Article • Journal of Virology, July 2011, ASM Journals

Professor Jonathan Luke Heeney
An Anti-HIV-1 V3 Loop Antibody Fully Protects Cross-Clade and Elicits T-Cell Immunity in Macaques Mucosally Challenged with an R5 Clade C SHIV

Article • PLoS ONE, March 2011, PLOS

Professor Jonathan Luke Heeney
No difference in Gag and Env immune-response profiles between vaccinated and non-vaccinated rhesus macaques that control immunodeficiency virus replication

Article • Journal of General Virology, September 2010, Society for General Microbiology

Professor Jonathan Luke Heeney
Correction: CD8+ NK cells are predominant in chimpanzees, characterized by high NCR expression and cytokine production, and preserved in chronic HIV-1 infection

Article • June 2010, Wiley

Professor Jonathan Luke Heeney
Potent adaptive immune responses induced against HIV-1 gp140 and influenza virus HA by a polyanionic carbomer

Article • Vaccine, March 2010, Elsevier

Professor Jonathan Luke Heeney
Analysis of Memory B Cell Responses and Isolation of Novel Monoclonal Antibodies with Neutralizing Breadth from HIV-1-Infected Individuals

Article • PLoS ONE, January 2010, PLOS

Professor Jonathan Luke Heeney
Viruses as vaccine vectors for infectious diseases and cancer

Article • Nature Reviews Microbiology, December 2009, Springer Science + Business Media

Dr Simon J Draper, Professor Jonathan Luke Heeney
Characterization of novel polyomaviruses from Bornean and Sumatran orang-utans

Article • Journal of General Virology, November 2009, Society for General Microbiology

Professor Jonathan Luke Heeney
An ill wind for wild chimps?

Article • Nature, July 2009, Springer Science + Business Media

Professor Jonathan Luke Heeney
Mhc haplotype H6 is associated with sustained control of SIVmac251 infection in Mauritian cynomolgus macaques

Article • Immunogenetics, April 2009, Springer Science + Business Media

Professor Jonathan Luke Heeney
Comparison of Human and Rhesus Macaque T-Cell Responses Elicited by Boosting with NYVAC Encoding Human Immunodeficiency Virus Type 1 Clade C Immunogens

Article • Journal of Virology, March 2009, ASM Journals

Professor Peter Liljeström, Professor Jonathan Luke Heeney
Acute-phase CD4+ T-cell proliferation and CD152 upregulation predict set-point virus replication in vaccinated simian-human immunodeficiency virus strain 89.6p-infected macaques

Article • Journal of General Virology, March 2009, Society for General Microbiology

Professor Jonathan Luke Heeney
NKp44 expression, phylogenesis and function in non-human primate NK cells

Article • International Immunology, January 2009, Oxford University Press (OUP)

Professor Jonathan Luke Heeney
Systemic neutralizing antibodies induced by long interval mucosally primed systemically boosted immunization correlate with protection from mucosal SHIV challenge

Article • Virology, December 2008, Elsevier

Professor Jonathan Luke Heeney
Prevention of SIV Rectal Transmission and Priming of T Cell Responses in Macaques after Local Pre-exposure Application of Tenofovir Gel

Article • PLoS Medicine, August 2008, PLOS

Professor Jonathan Luke Heeney
Seroprevalence of SV40-like polyomavirus infections in captive and free-ranging macaque species

Article • Journal of Medical Primatology, August 2008, Wiley

Professor Jonathan Luke Heeney
EV01: A phase I trial in healthy HIV negative volunteers to evaluate a clade C HIV vaccine, NYVAC-C undertaken by the EuroVacc Consortium

Article • Vaccine, June 2008, Elsevier

Professor Peter Liljeström, Professor Jonathan Luke Heeney
EV02: A Phase I trial to compare the safety and immunogenicity of HIV DNA-C prime-NYVAC-C boost to NYVAC-C alone

Article • Vaccine, June 2008, Elsevier

Professor Jonathan Luke Heeney
Improved HIV-1 specific T-cell responses by short-interval DNA tattooing as compared to intramuscular immunization in non-human primates

Article • Vaccine, June 2008, Elsevier

Professor Jonathan Luke Heeney
Better Protective Effects in Rhesus Macaques by Combining Systemic and Mucosal Application of a Dual Component Vector Vaccine After Rectal SHIV89.6P Challenge Compared to Systemic Vaccination Alone

Article • Viral Immunology, June 2008, Mary Ann Liebert Inc

Professor Jonathan Luke Heeney
HLA Homology within the C5 Domain Promotes Peptide Binding by HIV Type 1 gp120

Article • AIDS Research and Human Retroviruses, June 2008, Mary Ann Liebert Inc

Professor Jonathan Luke Heeney
Rhesus Macaque TRIM5 Alleles Have Divergent Antiretroviral Specificities

Article • Journal of Virology, May 2008, ASM Journals

Professor Jonathan Luke Heeney
Chimpanzee CD4+ T cells are relatively insensitive to HIV-1 envelope-mediated inhibition of CD154 up-regulation

Article • European Journal of Immunology, April 2008, Wiley

Professor Jonathan Luke Heeney
Independent evolution of an antiviral TRIMCyp in rhesus macaques

Article • Proceedings of the National Academy of Sciences, March 2008, Proceedings of the National Academy of Sciences

Professor Jonathan Luke Heeney
Aerosol immunization with NYVAC and MVA vectored vaccines is safe, simple, and immunogenic

Article • Proceedings of the National Academy of Sciences, February 2008, Proceedings of the National Academy of Sciences

Professor Jonathan Luke Heeney
Immune-response profiles induced by human immunodeficiency virus type 1 vaccine DNA, protein or mixed-modality immunization: increased protection from pathogenic simian human immunodeficiency virus viraemia with protein/DNA combination

Article • Journal of General Virology, February 2008, Society for General Microbiology

Professor Jonathan Luke Heeney
An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses

Article • The Journal of Experimental Medicine, January 2008, Rockefeller University Press

Professor Peter Liljeström, Professor Jonathan Luke Heeney
Differential CD4+ versus CD8+ T-Cell Responses Elicited by Different Poxvirus-Based Human Immunodeficiency Virus Type 1 Vaccine Candidates Provide Comparable Efficacies in Primates

Article • Journal of Virology, January 2008, ASM Journals

Professor Jonathan Luke Heeney
Molecular characterization of the first polyomavirus from a New World primate: squirrel monkey polyomavirus

Article • Journal of General Virology, January 2008, Society for General Microbiology

Professor Jonathan Luke Heeney
T cell receptor excision circles (TRECs) analysis during acute intrarectal infection of cynomolgus monkeys with pathogenic chimeric simian human immunodeficiency virus

Article • Virus Research, June 2007, Elsevier

Professor Jonathan Luke Heeney
A simian immunodeficiency virus V3 loop mutant that does not efficiently use CCR5 or common alternative coreceptors is moderately attenuated in vivo

Article • Virology, April 2007, Elsevier

Professor Stefan Pöhlmann, Professor Jonathan Luke Heeney
Evaluation of immunogenicity and efficacy of combined DNA and adjuvanted protein vaccination in a human immunodeficiency virus type 1/murine leukemia virus pseudotype challenge model

Article • Vaccine, March 2007, Elsevier

Professor Jonathan Luke Heeney
Old Rhesus Macaques Treated with Interleukin-7 Show Increased TREC Levels And Respond Well to Influenza Vaccination

Article • Rejuvenation Research, March 2007, Mary Ann Liebert Inc

Professor Jonathan Luke Heeney
Characterization of α-Defensins Plasma Levels in Macaca Fascicularis and Correlations with Virological Parameters during SHIV89.6Pcy11 Experimental Infection

Article • AIDS Research and Human Retroviruses, February 2007, Mary Ann Liebert Inc

Professor Jonathan Luke Heeney
Therapeutic immunization with Modified Vaccinia Virus Ankara (MVA) vaccines in SIV-infected rhesus monkeys undergoing antiretroviral therapy

Article • Journal of Medical Primatology, February 2007, Wiley

Professor Jonathan Luke Heeney
Upregulation of Indoleamine 2,3-Dioxygenase in Hepatitis C Virus Infection

Article • Journal of Virology, January 2007, ASM Journals

Professor Jonathan Luke Heeney
Comparison of intranasal with targeted lymph node immunization using PR8-Flu ISCOM adjuvanted HIV antigens in macaques

Article • Journal of Medical Virology, January 2007, Wiley

Professor Jonathan Luke Heeney
Vaccine-induced early control of hepatitis C virus infection in chimpanzees fails to impact on hepatic PD-1 and chronicity

Article • Hepatology, January 2007, Wiley

Professor Jonathan Luke Heeney
Immunological correlates of protection from HIV infection and disease

Article • Nature Immunology, December 2006, Springer Science + Business Media

Professor Jonathan Luke Heeney
Zoonotic viral diseases and the frontier of early diagnosis, control and prevention

Article • Journal of Internal Medicine, November 2006, Wiley

Professor Jonathan Luke Heeney
Sustained Conservation of CD4+ T Cells in Multiprotein Triple Modality-Immunized Rhesus Macaques after Intrarectal Challenge with Simian Immunodeficiency Virus

Article • Viral Immunology, September 2006, Mary Ann Liebert Inc

Professor Jonathan Luke Heeney
Origins of HIV and the Evolution of Resistance to AIDS

Article • Science, July 2006, American Association for the Advancement of Science

Professor Jonathan Luke Heeney
Transmission of Simian Immunodeficiency Virus SIVcpz and the Evolution of Infection in the Presence and Absence of Concurrent Human Immunodeficiency Virus Type 1 Infection in Chimpanzees

Article • Journal of Virology, July 2006, ASM Journals

Professor Jonathan Luke Heeney
Immunization with HIV-1 SF162-derived Envelope gp140 proteins does not protect macaques from heterologous simian-human immunodeficiency virus SHIV89.6P infection

Article • Virology, June 2006, Elsevier

Professor Jonathan Luke Heeney
Importance of the N-Distal AP-2 Binding Element in Nef for Simian Immunodeficiency Virus Replication and Pathogenicity in Rhesus Macaques

Article • Journal of Virology, May 2006, ASM Journals

Professor Jonathan Luke Heeney
Reduction of viral loads by multigenic DNA priming and adenovirus boosting in the SIVmac-macaque model

Article • Vaccine, March 2006, Elsevier

Professor Doris Wilflingseder, Professor Jonathan Luke Heeney
Modulation of Vaccine‐Induced Immune Responses to Hepatitis C Virus in Rhesus Macaques by Altering Priming before Adenovirus Boosting

Article • The Journal of Infectious Diseases, September 2005, Oxford University Press (OUP)

Professor Peter Liljeström, Professor Jonathan Luke Heeney
Systemic mobilization of antigen presenting cells, with a chimeric Flt-3 and G-CSF receptor agonist, during immunization of with HIV-1 antigens is insufficient to modulate immune responses or vaccine efficacy

Article • Vaccine, July 2005, Elsevier

Professor Jonathan Luke Heeney
Readily acquired secondary infections of human and simian immunodeficiency viruses following single intravenous exposure in non-human primates

Article • Journal of General Virology, December 2004, Society for General Microbiology

Professor Jonathan Luke Heeney
The Phylogeography of Orangutan Foamy Viruses Supports the Theory of Ancient Repopulation of Sumatra

Article • Journal of Virology, November 2004, ASM Journals

Professor Jonathan Luke Heeney
Direct Inoculation of Simian Immunodeficiency Virus from Sooty Mangabeys in Black Mangabeys (Lophocebus aterrimus): First Evidence of AIDS in a Heterologous African Species and Different Pathologic Outcomes of Experimental Infection

Article • Journal of Virology, November 2004, ASM Journals

Professor Jonathan Luke Heeney
T-cell-mediated protective efficacy of a systemic vaccine approach in cynomolgus monkeys after SIV mucosal challenge

Article • Journal of Medical Primatology, October 2004, Wiley

Professor Peter Liljeström, Professor Jonathan Luke Heeney
Vaccine protection from CD4+ T-cell loss caused by simian immunodeficiency virus (SIV) mac251 is afforded by sequential immunization with three unrelated vaccine vectors encoding multiple SIV antigens

Article • Journal of General Virology, October 2004, Society for General Microbiology

Professor Jonathan Luke Heeney
Long-term protection against SHIV89.6P replication in HIV-1 Tat vaccinated cynomolgus monkeys

Article • Vaccine, September 2004, Elsevier

Professor Jonathan Luke Heeney
Macaques infected long-term with attenuated simian immunodeficiency virus (SIVmac) remain resistant to wild-type challenge, despite declining cytotoxic T lymphocyte responses to an immunodominant epitope

Article • Journal of General Virology, September 2004, Society for General Microbiology

Professor Jonathan Luke Heeney
CCR5 targeted SIV vaccination strategy preventing or inhibiting SIV infection

Article • Vaccine, August 2004, Elsevier

Professor Jonathan Luke Heeney
Enhanced cellular immunity and systemic control of SHIV infection by combined parenteral and mucosal administration of a DNA prime MVA boost vaccine regimen

Article • Journal of General Virology, August 2004, Society for General Microbiology

Professor Jonathan Luke Heeney
Requirement of diverse T-helper responses elicited by HIV vaccines: induction of highly targeted humoral and CTL responses

Article • Expert Review of Vaccines, August 2004, Taylor & Francis

Professor Jonathan Luke Heeney
Nef Proteins from Simian Immunodeficiency Virus-Infected Chimpanzees Interact with p21-Activated Kinase 2 and Modulate Cell Surface Expression of Various Human Receptors

Article • Journal of Virology, July 2004, ASM Journals

Professor Jonathan Luke Heeney
Circular viral DNA detection and junction sequence analysis from PBMC of SHIV-infected cynomolgus monkeys with undetectable virus plasma RNA

Article • Virology, July 2004, Elsevier

Professor Jonathan Luke Heeney
Protective efficacy of a multicomponent vector vaccine in cynomolgus monkeys after intrarectal simian immunodeficiency virus challenge

Article • Journal of General Virology, May 2004, Society for General Microbiology

Professor Jonathan Luke Heeney
Qualitative T-Helper Responses to Multiple Viral Antigens Correlate with Vaccine-Induced Immunity to Simian/Human Immunodeficiency Virus Infection

Article • Journal of Virology, April 2004, ASM Journals

Professor Jonathan Luke Heeney
Increase in plasmacytoid and myeloid dendritic cells by progenipoietin-1, a chimeric Flt-3 and G-CSF receptor agonist, in SIV-Infected rhesus macaques

Article • Human Immunology, April 2004, Elsevier

Professor Jonathan Luke Heeney
Long-term persistence of HIV-1 vaccine-induced CD4+CD45RA–CD62L–CCR7– memory T-helper cells

Article • AIDS, April 2004, Wolters Kluwer Health

Professor Jonathan Luke Heeney
Early protection against pathogenic virus infection at a mucosal challenge site after vaccination with attenuated simian immunodeficiency virus

Article • Proceedings of the National Academy of Sciences, February 2004, Proceedings of the National Academy of Sciences

Professor Jonathan Luke Heeney
Neutralization of primary HIV-1 SF13 can be detected in extended incubation phase assays with sera from monkeys immunized with recombinant HIV-1 SF2 gp120

Article • Vaccine, January 2004, Elsevier

Professor Jonathan Luke Heeney
Control of Heterologous Hepatitis C Virus Infection in Chimpanzees Is Associated with the Quality of Vaccine-Induced Peripheral T-Helper Immune Response

Article • Journal of Virology, January 2004, ASM Journals

Professor Jonathan Luke Heeney
A novel HIV-CCR5 receptor vaccine strategy in the control of mucosal SIV/HIV infection

Article • AIDS, January 2004, Wolters Kluwer Health

Dr Lesley A Bergmeier, Professor Jonathan Luke Heeney
Experimental norovirus infections in non-human primates

Article • Journal of Medical Virology, January 2004, Wiley

Professor Jonathan Luke Heeney
A novel simian immunodeficiency virus isolated from a Schmidt's guenon (Cercopithecus ascanius schmidti)

Article • Journal of General Virology, January 2004, Society for General Microbiology

Professor Jonathan Luke Heeney
Chronic hepatitis C virus infection established and maintained in chimpanzees independent of dendritic cell impairment

Article • October 2003, Wiley

Professor Jonathan Luke Heeney
Single-cycle immunodeficiency viruses provide strategies for uncoupling in vivo expression levels from viral replicative capacity and for mimicking live-attenuated SIV vaccines

Article • Virology, September 2003, Elsevier

Professor Jonathan Luke Heeney
Structural and Evolutionary Analysis of an Orangutan Foamy Virus

Article • Journal of Virology, August 2003, ASM Journals

Professor Jonathan Luke Heeney
Foci of Endemic Simian Immunodeficiency Virus Infection in Wild-Living Eastern Chimpanzees (Pan troglodytes schweinfurthii)

Article • Journal of Virology, July 2003, ASM Journals

Professor Jonathan Luke Heeney
Specific nature of cellular immune responses elicited by chimpanzees against HIV-1

Article • Human Immunology, July 2003, Elsevier

Professor Jonathan Luke Heeney
Gene therapy in nonhuman primate models of human autoimmune disease

Article • Gene Therapy, May 2003, Springer Science + Business Media

Professor Jonathan Luke Heeney
Reduced transmission and prevalence of simian T-cell lymphotropic virus in a closed breeding colony of chimpanzees (Pan troglodytes verus)

Article • Journal of General Virology, March 2003, Society for General Microbiology

Professor Jonathan Luke Heeney
Prevention of Disease Induced by a Partially Heterologous AIDS Virus in Rhesus Monkeys by Using an Adjuvanted Multicomponent Protein Vaccine

Article • Journal of Virology, January 2003, ASM Journals

Professor Jonathan Luke Heeney
Human and simian immunodeficiency virus-infected chimpanzees do not have increased intracellular levels of ?-chemokines in contrast to infected humans

Article • Journal of Medical Virology, January 2003, Wiley

Professor Jonathan Luke Heeney
Replication, Immunogenicity, and Protective Properties of Live-Attenuated Simian Immunodeficiency Viruses Expressing Interleukin-4 or Interferon-γ

Article • Virology, January 2003, Elsevier

Professor Jonathan Luke Heeney
T-Cell Receptor:CD3 Down-Regulation Is a Selected In Vivo Function of Simian Immunodeficiency Virus Nef but Is Not Sufficient for Effective Viral Replication in Rhesus Macaques

Article • Journal of Virology, December 2002, ASM Journals

Professor Jonathan Luke Heeney
Evidence for an ancient selective sweep in the MHC class I gene repertoire of chimpanzees

Article • Proceedings of the National Academy of Sciences, August 2002, Proceedings of the National Academy of Sciences

Professor Jonathan Luke Heeney
In vitro susceptibility to infection with SIVcpz and HIV-1 is lower in chimpanzee than in human peripheral blood mononuclear cells

Article • Journal of Medical Virology, May 2002, Wiley

Professor Jonathan Luke Heeney
The critical role of CD4+ T-cell help in immunity to HIV

Article • Vaccine, May 2002, Elsevier

Professor Jonathan Luke Heeney
Stimulation of both humoral and cellular immune responses to HIV-1 gp120 by interleukin-12 in Rhesus macaques

Article • Vaccine, May 2002, Elsevier

Professor Jonathan Luke Heeney
In Vitro Replication of SIVcpz Is Suppressed by β-Chemokines and CD8+ T Cells But Not by Natural Killer Cells of Infected Chimpanzees

Article • AIDS Research and Human Retroviruses, March 2002, Mary Ann Liebert Inc

Professor Jonathan Luke Heeney
SIVcpz in Wild Chimpanzees

Article • Science, January 2002, American Association for the Advancement of Science

Professor Jonathan Luke Heeney
Decreased expression of IL-2 in central and effector CD4 memory cells during progression to AIDS in rhesus macaques

Article • AIDS, December 2001, Wolters Kluwer Health

Professor Jonathan Luke Heeney
Rational development of prophylactic HIV vaccines based on structural and regulatory proteins

Article • Vaccine, November 2001, Elsevier

Professor Jonathan Luke Heeney
Differences in early virus loads with different phenotypic variants of HIV-1 and SIVcpz in chimpanzees

Article • AIDS, November 2001, Wolters Kluwer Health

Professor Jonathan Luke Heeney
Editorial

Article • Immunology Letters, November 2001, Elsevier

Professor Jonathan Luke Heeney
Rhesus macaque and chimpanzee DC-SIGN act as HIV/SIV gp120 trans-receptors, similar to human DC-SIGN

Article • Immunology Letters, November 2001, Elsevier

Professor Jonathan Luke Heeney
Characteristics of a Pathogenic Molecular Clone of an End-Stage Serum-Derived Variant of Simian Immunodeficiency Virus (SIVF359)

Article • Journal of Virology, October 2001, ASM Journals

Professor Jonathan Luke Heeney
Simian Immunodeficiency Virus in Which nef and U3 Sequences Do Not Overlap Replicates Efficiently In Vitro and In Vivo in Rhesus Macaques

Article • Journal of Virology, September 2001, ASM Journals

Professor Jonathan Luke Heeney
No Evidence of HIV and SIV Sequences in Two Separate Lots of Polio Vaccines Used in the First U.S. Polio Vaccine Campaign

Article • Virology, August 2001, Elsevier

Professor Jonathan Luke Heeney
Protection from Secondary Human Immunodeficiency Virus Type 1 Infection in Chimpanzees Suggests the Importance of Antigenic Boosting and a Possible Role for Cytotoxic T Cells

Article • The Journal of Infectious Diseases, July 2001, Oxford University Press (OUP)

Professor Jonathan Luke Heeney
Enhanced simian immunodeficiency virus-specific immune responses in macaques induced by priming with recombinant Semliki Forest virus and boosting with modified vaccinia virus Ankara

Article • Vaccine, May 2001, Elsevier

Professor Peter Liljeström, Professor Jonathan Luke Heeney
Approaches to the development of broadly protective HIV vaccines: challenges posed by the genetic, biological and antigenic variability of HIV-1

Article • AIDS, April 2001, Wolters Kluwer Health

Professor Jonathan Luke Heeney
Independence of Herpesvirus-Induced T Cell Lymphoma from Viral Cyclin D Homologue

Article • The Journal of Experimental Medicine, March 2001, Rockefeller University Press

Professor Jonathan Luke Heeney
Changes in dendritic cell subsets in the lymph nodes of rhesus macaques after application of glucocorticoids

Article • Human Immunology, March 2001, Elsevier

Professor Jonathan Luke Heeney
Safety and immunogenicity of ALVAC wild-type human p53 (vCP207) by the intravenous route in rhesus macaques

Article • Vaccine, February 2001, Elsevier

Professor Jonathan Luke Heeney
Enhanced Cellular Immune Response and Reduced CD8+ Lymphocyte Apoptosis in Acutely SIV-Infected Rhesus Macaques after Short-Term Antiretroviral Treatment

Article • Virology, January 2001, Elsevier

Professor Jonathan Luke Heeney
Mucosal Exposure to Subinfectious Doses of SIV Primes Gut-Associated Antibody-Secreting Cells and T Cells: Lack of Enhancement by Nonneutralizing Antibody

Article • Virology, January 2001, Elsevier

Dr Lesley A Bergmeier, Professor Jonathan Luke Heeney
OVERVIEW

Article • AIDS, January 2001, Wolters Kluwer Health

Professor Jonathan Luke Heeney
Genetic variability of the V1 and V2env domains of SIVcpz-ant and neutralization pattern of plasma viruses in a chimpanzee infected naturally

Article • Journal of Medical Virology, January 2001, Wiley

Professor Jonathan Luke Heeney
Herpesvirus Saimiri vFLIP Provides an Antiapoptotic Function but Is Not Essential for Viral Replication, Transformation, or Pathogenicity

Article • Journal of Virology, December 2000, ASM Journals

Professor Jonathan Luke Heeney
Increased Neutralization Sensitivity and Reduced Replicative Capacity of Human Immunodeficiency Virus Type 1 after Short-Term In Vivo or In Vitro Passage through Chimpanzees

Article • Journal of Virology, September 2000, ASM Journals

Professor Jonathan Luke Heeney
Suppression of Acute Viremia by Short-Term Postexposure Prophylaxis of Simian/Human Immunodeficiency Virus SHIV-RT-Infected Monkeys with a Novel Reverse Transcriptase Inhibitor (GW420867) Allows for Development of Potent Antiviral Immune Responses Resu...

Article • Journal of Virology, July 2000, ASM Journals

Professor Jonathan Luke Heeney
Evidence for Viral Virulence as a Predominant Factor Limiting Human Immunodeficiency Virus Vaccine Efficacy

Article • Journal of Virology, May 2000, ASM Journals

Professor Jonathan Luke Heeney
Antiretroviral Therapy during Primary Immunodeficiency Virus Infection Can Induce Persistent Suppression of Virus Load and Protection from Heterologous Challenge in Rhesus Macaques

Article • Journal of Virology, February 2000, ASM Journals

Professor Jonathan Luke Heeney
A strategy for cloning infectious molecular clones of retroviruses from serum or plasma

Article • Journal of Virological Methods, January 2000, Elsevier

Professor Jonathan Luke Heeney
Co‐receptor Usage of BOB/GPR15 in Addition to CCR5 Has No Significant Effect on Replication of Simian Immunodeficiency Virus In Vivo

Article • The Journal of Infectious Diseases, November 1999, Oxford University Press (OUP)

Professor Stefan Pöhlmann, Professor Jonathan Luke Heeney
Induction of inhibitory antibodies to the CCR5 chemokine receptor and their complementary role in preventing SIV infection in macaques

Article • European Journal of Immunology, August 1999, Wiley

Dr Lesley A Bergmeier, Professor Jonathan Luke Heeney
Control of SHIV-89.6P-infection of cynomolgus monkeys by HIV-1 Tat protein vaccine

Article • Nature Reports Stem Cells, June 1999, Springer Science + Business Media

Professor Jonathan Luke Heeney
Immune correlates of protection from HIV and AIDS – more answers but yet more questions

Article • Immunology Today, June 1999, Elsevier

Professor Jonathan Luke Heeney
The Acidic Region and Conserved Putative Protein Kinase C Phosphorylation Site in Nef Are Important for SIV Replication in Rhesus Macaques

Article • Virology, April 1999, Elsevier

Professor Jonathan Luke Heeney
Differential cytotoxic T-lymphocyte (CTL) responses in HIV-1 immunised sibling chimpanzees with shared MHC haplotypes

Article • Immunology Letters, March 1999, Elsevier

Professor Jonathan Luke Heeney
HIV-1 vaccine-induced immune responses which correlate with protection from SHIV infection: compiled preclinical efficacy data from trials with ten different HIV-1 vaccine candidates

Article • Immunology Letters, March 1999, Elsevier

Professor Jonathan Luke Heeney
The Relative Resistance of HIV Type 1-Infected Chimpanzees to AIDS Correlates with the Maintenance of Follicular Architecture and the Absence of Infiltration by CD8+ Cytotoxic T Lymphocytes

Article • AIDS Research and Human Retroviruses, March 1999, Mary Ann Liebert Inc

Professor Jonathan Luke Heeney
Cellular vaccines

Article • Research in Immunology, September 1998, Elsevier

Professor Jonathan Luke Heeney
β-Chemokines and neutralizing antibody titers correlate with sterilizing immunity generated in HIV-1 vaccinated macaques

Article • Proceedings of the National Academy of Sciences, September 1998, Proceedings of the National Academy of Sciences

Professor Jonathan Luke Heeney
Cytotoxic T Cells and Neutralizing Antibodies Induced in Rhesus Monkeys by Virus-like Particle HIV Vaccines in the Absence of Protection from SHIV Infection

Article • Virology, May 1998, Elsevier

Professor Jonathan Luke Heeney
Generation of CD8 suppressor factor and β chemokines, induced by xenogeneic immunization, in the prevention of simian immunodeficiency virus infection in macaques

Article • Proceedings of the National Academy of Sciences, April 1998, Proceedings of the National Academy of Sciences

Professor Jonathan Luke Heeney
A clinically relevant HIV-1 subunit vaccine protects rhesus macaques from in vivo passaged simian–human immunodeficiency virus infection

Article • AIDS, March 1998, Wolters Kluwer Health

Professor Jonathan Luke Heeney
A recombinant prime, peptide boost vaccination strategy can focus the immune response on to more than one epitope even though these may not be immunodominant in the complex immunogen

Article • Vaccine, October 1997, Elsevier

Professor Jonathan Luke Heeney
Comparison ofin Vitroandin VivoInfectivity of Different Clade B HIV-1 Envelope Chimeric Simian/Human Immunodeficiency Viruses inMacaca mulatta

Article • Virology, September 1997, Elsevier

Professor Jonathan Luke Heeney
Long Terminal Repeat U3 Length Polymorphism of Human Foamy Virus

Article • Virology, April 1997, Elsevier

Professor Jonathan Luke Heeney
European contribution to the science, prevention and management of HIV infection

Article • Vaccine, April 1997, Elsevier

Professor Jonathan Luke Heeney
Immune correlates of protection from HIV infection and AIDS

Article • Immunology Today, January 1997, Elsevier

Professor Jonathan Luke Heeney
The effect of recombinant human interferon α BD compared to interferon α 2b on SIV infection in rhesus macaques

Article • Antiviral Research, August 1996, Elsevier

Professor Jonathan Luke Heeney
Lymphocytes Are the Major Reservoir for Foamy Viruses in Peripheral Blood

Article • Virology, July 1996, Elsevier

Professor Jonathan Luke Heeney
Editorial

Article • Immunology Letters, June 1996, Elsevier

Professor Jonathan Luke Heeney
Comparative analysis of apoptosis in HIV-infected humans and chimpanzees: relation with lymphocyte activation

Article • Immunology Letters, June 1996, Elsevier

Professor Jonathan Luke Heeney
Immune strategies utilized by lentivirus infected chimpanzees to resist progression to AIDS

Article • Immunology Letters, June 1996, Elsevier

Professor Jonathan Luke Heeney
The role of major histocompatibility complex polymorphisms on SIV infection in rhesus macaques

Article • Immunology Letters, June 1996, Elsevier

Professor Jonathan Luke Heeney
Absence of serological evidence for foamy virus infection in patients with amyotrophic lateral sclerosis

Article • Journal of Medical Virology, March 1996, Wiley

Professor Jonathan Luke Heeney
Primate models for AIDS vaccine development

Article • AIDS, January 1996, Wolters Kluwer Health

Professor Jonathan Luke Heeney
AIDS: a disease of impaired Th-cell renewal?

Article • Immunology Today, November 1995, Elsevier

Professor Jonathan Luke Heeney
Virologic and Serologic Characteristics of a Natural Chimpanzee Lentivirus Infection

Article • Virology, August 1995, Elsevier

Professor Jonathan Luke Heeney
Comparison of the Response to T-cell Activation by Integrated HIV-1 and HTLV-1 LTR-lacZ Vectors

Article • Virology, June 1995, Elsevier

Professor Jonathan Luke Heeney
Antigenicity and immunogenicity of recombinant envelope glycoproteins of SIVmac32H with different in vivo passage histories

Article • Vaccine, January 1995, Elsevier

Professor Jonathan Luke Heeney
Detection of human T-cell leukaemia virus 1 permissive cells using cell lines producing selectable recombinant virions

Article • Journal of Virological Methods, December 1994, Elsevier

Professor Jonathan Luke Heeney
Major histocompatibility complex class I-associated vaccine protection from simian immunodeficiency virus-infected peripheral blood cells

Article • The Journal of Experimental Medicine, August 1994, Rockefeller University Press

Professor Jonathan Luke Heeney
Protection of rhesus macaques from SIV infection by immunization with different experimental SIV vaccines

Article • Vaccine, January 1994, Elsevier

Professor Jonathan Luke Heeney
Different proliferative response of human and chimpanzee lymphocytes after contact with human immunodeficiency virus type 1 gp120

Article • European Journal of Immunology, January 1994, Wiley

Professor Jonathan Luke Heeney
Cytochemical analysis of human T cell leukaemia virus 1 LTR-regulated β-galactosidase gene expression using a novel integrated cell system

Article • Journal of Virological Methods, December 1993, Elsevier

Professor Jonathan Luke Heeney
Biological and pathological consequences of feline infectious peritonitis virus infection in the cheetah

Article • Archives of Virology, September 1988, Springer Science + Business Media

Professor Jonathan Luke Heeney
Bovine ocular squamous cell carcinoma: Ultrastructural characteristics in vitro

Article • Veterinary Research Communications, December 1983, Springer Science + Business Media

Professor Jonathan Luke Heeney
Preface

Article • Cambridge University Press

Professor Jonathan Luke Heeney
Ebola: The Plague of 2014/2015

Article • Cambridge University Press

Professor Jonathan Luke Heeney
Foreword

Article • Cambridge University Press

Professor Jonathan Luke Heeney