All Stories

  1. SARS-CoV-2 Delta, not Omicron, drives Transferrin receptor-1 upregulation, inflammatory activation, and viral persistence in macrophages

    Article • Biomedicine & Pharmacotherapy, July 2026, Elsevier

    Professor Doris Wilflingseder

  2. What’s in a NAM?

    Article • Lab Animal, May 2026, Springer Science + Business Media

    Professor Doris Wilflingseder

  3. Imaging and safety profiling of inhaled siRNA RyR2 in human respiratory models

    Article • Archives of Toxicology, April 2026, Springer Science + Business Media

    Professor Doris Wilflingseder

  4. Aloe-derived polysaccharides (APS) mitigate SARS-CoV-2 Omicron BQ1.1 infection by preserving epithelial integrity and reducing viral load in human airway epithelial (HAE) cultures

    Article • Biomedicine & Pharmacotherapy, November 2025, Elsevier

    Professor Doris Wilflingseder

  5. Machine Learning to Identify Critical Biomarker Profiles in New SARS-CoV-2 Variants

    Article • Microorganisms, April 2024, MDPI AG

    Professor Doris Wilflingseder

  6. Control of complement-induced inflammatory responses to SARS-CoV-2 infection by anti-SARS-CoV-2 antibodies

    Article • The EMBO Journal, February 2024, Springer Science + Business Media

    Professor Doris Wilflingseder

  7. Vaccination and Omicron BA.1/BA.2 Convalescence Enhance Systemic but Not Mucosal Immunity against BA.4/5

    Article • Microbiology Spectrum, June 2023, ASM Journals

    Professor Doris Wilflingseder

  8. Antiviral drugs block replication of highly immune-evasive Omicron subvariants ex vivo, but fail to reduce tissue inflammation

    Article • Antiviral Research, May 2023, Elsevier

    Professor Doris Wilflingseder

  9. Antimicrobial efficacy and inactivation kinetics of a novel LED-based UV-irradiation technology

    Article • Journal of Hospital Infection, May 2023, Elsevier

    Professor Doris Wilflingseder

  10. GlyPerA™ effectively shields airway epithelia from SARS-CoV-2 infection and inflammatory events

    Article • Respiratory Research, March 2023, Springer Science + Business Media

    Professor Doris Wilflingseder

  11. Immunity of Heterologously and Homologously Boosted or Convalescent Individuals Against Omicron BA.1, BA.2, and BA.4/5 Variants

    Article • The Journal of Infectious Diseases, March 2023, Oxford University Press (OUP)

    Professor Doris Wilflingseder

  12. Correction: ColdZyme® protects airway epithelia from infection with BA.4/5

    Article • Respiratory Research, January 2023, Springer Science + Business Media

    Professor Doris Wilflingseder

  13. Guidelines for visualization and analysis of DC in tissues using multiparameter fluorescence microscopy imaging methods

    Article • European Journal of Immunology, January 2023, Wiley

    Professor Doris Wilflingseder

  14. More Efficient Complement Activation by Anti–Aquaporin-4 Compared With Anti–Myelin Oligodendrocyte Glycoprotein Antibodies

    Article • Neurology Neuroimmunology & Neuroinflammation, January 2023, Wolters Kluwer Health

    Professor Doris Wilflingseder

  15. Inhalation of Low Molecular Weight Heparins as Prophylaxis against SARS-CoV-2

    Article • mBio, December 2022, ASM Journals

    Professor Doris Wilflingseder

  16. Serum Neutralization Against SARS-CoV-2 Variants Is Heterogenic and Depends on Vaccination Regimen

    Article • The Journal of Infectious Diseases, November 2022, Oxford University Press (OUP)

    Professor Doris Wilflingseder

  17. The Current Status and Work of Three Rs Centres and Platforms in Europe*

    Article • Alternatives to Laboratory Animals, November 2022, SAGE Publications

    Professor Doris Wilflingseder

  18. ColdZyme® protects airway epithelia from infection with BA.4/5

    Article • Respiratory Research, October 2022, Springer Science + Business Media

    Professor Doris Wilflingseder

  19. Cilgavimab/Tixagevimab as alternative therapeutic approach for BA.2 infections

    Article • Frontiers in Medicine, September 2022, Frontiers

    Professor Doris Wilflingseder

  20. Salivary IgAs and Their Role in Mucosal Neutralization of SARS-CoV-2 Variants of Concern

    Article • Journal of Clinical Microbiology, September 2022, ASM Journals

    Professor Doris Wilflingseder

  21. Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer

    Article • September 2022, openRxiv

    Professor Doris Wilflingseder

  22. Immune Responses Against SARS-CoV-2 WT and Delta Variant in Elderly BNT162b2 Vaccinees

    Article • Frontiers in Immunology, June 2022, Frontiers

    Professor Doris Wilflingseder

  23. 3D bioprinted, vascularized neuroblastoma tumor environment in fluidic chip devices for precision medicine drug testing

    Article • Biofabrication, April 2022, Institute of Physics Publishing

    Professor Doris Wilflingseder

  24. Comparative analyses of IgG/IgA neutralizing effects induced by three COVID-19 vaccines against variants of concern

    Article • Journal of Allergy and Clinical Immunology, April 2022, Elsevier

    Professor Doris Wilflingseder

  25. Calcium current modulation by the γ1 subunit depends on alternative splicing of CaV1.1

    Article • Journal of General Physiology, March 2022, Rockefeller University Press

    Professor Doris Wilflingseder

  26. The Rise of Three Rs Centres and Platforms in Europe*

    Article • Alternatives to Laboratory Animals, March 2022, SAGE Publications

    Professor Doris Wilflingseder

  27. HIV-1 Trans Infection via TNTs Is Impeded by Targeting C5aR

    Article • Biomolecules, February 2022, MDPI AG

    Professor Doris Wilflingseder

  28. Wie sich COVID-19 in der 3D-Zellkultur simulieren lässt

    Article • BIOspektrum, February 2022, Springer Science + Business Media

    Professor Doris Wilflingseder

  29. Third Virtual Summer School 3Rs for ONE Science: Alternative methods: From complexity to predictivity

    Article • ALTEX, January 2022, ALTEX Edition

    Professor Doris Wilflingseder

  30. Calcium current modulation by the γ 1 subunit depends on alternative splicing of Ca V 1.1

    Article • November 2021, openRxiv

    Professor Doris Wilflingseder

  31. Complement Potentiates Immune Sensing of HIV-1 and Early Type I Interferon Responses

    Article • mBio, October 2021, ASM Journals

    Professor Doris Wilflingseder

  32. SARS-CoV-2–infected primary human airway epithelia illustrate mucus hypersecretion

    Article • Journal of Allergy and Clinical Immunology, September 2021, Elsevier

    Professor Doris Wilflingseder

  33. P80 Natural Essence Exerts Efficient Anti-HIV-1- as Well as Adjuvant Effects in DCs

    Article • Vaccines, August 2021, MDPI AG

    Professor Doris Wilflingseder

  34. Potent SARS-CoV-2-Specific T Cell Immunity and Low Anaphylatoxin Levels Correlate With Mild Disease Progression in COVID-19 Patients

    Article • Frontiers in Immunology, June 2021, Frontiers

    Professor Doris Wilflingseder

  35. C5aR inhibition of nonimmune cells suppresses inflammation and maintains epithelial integrity in SARS-CoV-2–infected primary human airway epithelia

    Article • Journal of Allergy and Clinical Immunology, June 2021, Elsevier

    Professor Doris Wilflingseder

  36. Oxidant therapy improves adipogenic differentiation of adipose-derived stem cells in human wound healing

    Article • Stem Cell Research & Therapy, May 2021, Springer Science + Business Media

    Professor Doris Wilflingseder

  37. Expression of virulence factors by Pseudomonas aeruginosa biofilm after bacteriophage infection

    Article • Microbial Pathogenesis, May 2021, Elsevier

    Professor Doris Wilflingseder

  38. HIV-1 subverts the complement system in semen to enhance viral transmission

    Article • Mucosal Immunology, May 2021, Elsevier

    Professor Doris Wilflingseder

  39. ColdZyme Maintains Integrity in SARS-CoV-2-Infected Airway Epithelia

    Article • mBio, April 2021, ASM Journals

    Professor Doris Wilflingseder

  40. Dexamethasone Creates a Suppressive Microenvironment and Promotes Aspergillus fumigatus Invasion in a Human 3D Epithelial/Immune Respiratory Model

    Article • Journal of Fungi, March 2021, MDPI AG

    Professor Doris Wilflingseder

  41. Dexamethasone Promotes Aspergillus fumigatus Growth in Macrophages by Triggering M2 Repolarization via Targeting PKM2

    Article • Journal of Fungi, January 2021, MDPI AG

    Professor Doris Wilflingseder

  42. Notch-Mediated Generation of Monocyte-Derived Langerhans Cells: Phenotype and Function

    Article • Journal of Investigative Dermatology, January 2021, Elsevier

    Professor Doris Wilflingseder

  43. Second Virtual Summer School: Alternative methods in science: Towards model complexity

    Article • ALTEX, January 2021, ALTEX Edition

    Professor Doris Wilflingseder

  44. Role of Complement Receptors (CRs) on DCs in Anti-HIV-1 Immunity

    Article • Frontiers in Immunology, November 2020, Frontiers

    Professor Doris Wilflingseder

  45. Combined effects of exposure to engineered silver nanoparticles and the water-soluble fraction of crude oil in the marine copepod Calanus finmarchicus

    Article • Aquatic Toxicology, October 2020, Elsevier

    Professor Doris Wilflingseder

  46. CR4 Signaling Contributes to a DC-Driven Enhanced Immune Response Against Complement-Opsonized HIV-1

    Article • Frontiers in Immunology, August 2020, Frontiers

    Professor Doris Wilflingseder

  47. Virtual Summer School: Alternative methods and models in science: A multidisciplinary in vitro approach

    Article • ALTEX, January 2020, ALTEX Edition

    Professor Doris Wilflingseder

  48. Turning the World Upside-Down in Cellulose for Improved Culturing and Imaging of Respiratory Challenges within a Human 3D Model

    Article • Cells, October 2019, MDPI AG

    Professor Doris Wilflingseder

  49. Phosphorylation of Drosophila CENP-A on serine 20 regulates protein turn-over and centromere-specific loading

    Article • Nucleic Acids Research, September 2019, Oxford University Press (OUP)

    Professor Doris Wilflingseder

  50. Correction to: Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data

    Article • Genome Medicine, July 2019, Springer Science + Business Media

    Professor Doris Wilflingseder

  51. Co- but not Sequential Infection of DCs Boosts Their HIV-Specific CTL-Stimulatory Capacity

    Article • Frontiers in Immunology, May 2019, Frontiers

    Professor Doris Wilflingseder

  52. Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data

    Article • Genome Medicine, May 2019, Springer Science + Business Media

    Professor Doris Wilflingseder

  53. Erratum to ‘High-quality endoscope reprocessing decreases endoscope contamination’ [Clinical Microbiology and Infection, Volume 24, Issue 10 (October 2018) Pages 1101.e1–1101.e6]

    Article • Clinical Microbiology and Infection, March 2019, Elsevier

    Professor Doris Wilflingseder

  54. β-1,3-glucan-lacking Aspergillus fumigatus mediates an efficient antifungal immune response by activating complement and dendritic cells

    Article • Virulence, October 2018, Taylor & Francis

    Dr Johannes Wagener, Lukas Huber, Professor Hubertus Haas, Professor Doris Wilflingseder, Axel Brakhage

  55. High-quality endoscope reprocessing decreases endoscope contamination

    Article • Clinical Microbiology and Infection, October 2018, Elsevier

    Professor Doris Wilflingseder

  56. The Evolutionary Conserved γ-Core Motif Influences the Anti-Candida Activity of the Penicillium chrysogenum Antifungal Protein PAF

    Article • Frontiers in Microbiology, July 2018, Frontiers

    Professor Doris Wilflingseder

  57. Aspergillus terreus: Novel lessons learned on amphotericin B resistance

    Article • Medical Mycology, March 2018, Oxford University Press (OUP)

    Professor Doris Wilflingseder

  58. Towards optimisation of induced pluripotent cell culture: Extracellular acidification results in growth arrest of iPSC prior to nutrient exhaustion

    Article • Toxicology in Vitro, December 2017, Elsevier

    Professor Doris Wilflingseder

  59. Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data

    Article • November 2017, openRxiv

    Professor Doris Wilflingseder

  60. Fast-track development of an in vitro 3D lung/immune cell model to study Aspergillus infections

    Article • Scientific Reports, September 2017, Springer Science + Business Media

    Professor Doris Wilflingseder

  61. Invasive candidiasis: future directions in non-culture based diagnosis

    Article • Expert Review of Anti-infective Therapy, September 2017, Taylor & Francis

    Professor Doris Wilflingseder

  62. Oxidative Stress Response Tips the Balance in Aspergillus terreus Amphotericin B Resistance

    Article • Antimicrobial Agents and Chemotherapy, July 2017, ASM Journals

    Professor Doris Wilflingseder

  63. Promising immunotherapy against fungal diseases

    Article • Expert Opinion on Biological Therapy, May 2017, Taylor & Francis

    Professor Doris Wilflingseder

  64. Generation of Human Monocyte-derived Dendritic Cells from Whole Blood

    Article • Journal of Visualized Experiments, December 2016, MyJove Corporation

    Professor Doris Wilflingseder

  65. Periodontal Ehlers-Danlos Syndrome Is Caused by Mutations in C1R and C1S , which Encode Subcomponents C1r and C1s of Complement

    Article • The American Journal of Human Genetics, November 2016, Elsevier

    Professor Marcus Schmitt-Egenolf, Professor Doris Wilflingseder

  66. A Cinnamon-Derived Procyanidin Compound Displays Anti-HIV-1 Activity by Blocking Heparan Sulfate- and Co-Receptor- Binding Sites on gp120 and Reverses T Cell Exhaustion via Impeding Tim-3 and PD-1 Upregulation

    Article • PLOS One, October 2016, PLOS

    Professor Doris Wilflingseder

  67. Complement-Opsonized HIV-1 Overcomes Restriction in Dendritic Cells

    Article • PLoS Pathogens, June 2015, PLOS

    Professor Doris Wilflingseder

  68. Blocking Hsp70 Enhances the Efficiency of Amphotericin B Treatment against Resistant Aspergillus terreus Strains

    Article • Antimicrobial Agents and Chemotherapy, April 2015, ASM Journals

    Professor Doris Wilflingseder

  69. Immediate T-Helper 17 Polarization Upon Triggering CD11b/c on HIV-Exposed Dendritic Cells

    Article • The Journal of Infectious Diseases, January 2015, Oxford University Press (OUP)

    Professor Doris Wilflingseder

  70. The Viral Make-Up Makes a World of Difference

    Article • AIDS Research and Human Retroviruses, July 2014, Mary Ann Liebert Inc

    Professor Doris Wilflingseder

  71. Hepcidin as a predictive factor and therapeutic target in erythropoiesis-stimulating agent treatment for anemia of chronic disease in rats

    Article • Haematologica, June 2014, Ferrata Storti Foundation (Haematologica)

    Professor Doris Wilflingseder

  72. Shiga Toxin 2 Reduces Complement Inhibitor CD59 Expression on Human Renal Tubular Epithelial and Glomerular Endothelial Cells

    Article • Infection and Immunity, May 2013, ASM Journals

    Professor Doris Wilflingseder

  73. Role of Dendritic Cell Subsets on HIV-Specific Immunity

    Article • April 2013, IntechOpen

    Professor Doris Wilflingseder

  74. Minireview: host defence in invasive aspergillosis

    Article • Mycoses, February 2013, Wiley

    Professor Emmanuel Roilides, Professor Doris Wilflingseder

  75. Protein Kinase C Overexpression Does Not Enhance Immune-Stimulatory Surface Markers of Vaccinia-Infected Dendritic Cells and DC Cell Lines

    Article • Immunological Investigations, January 2013, Taylor & Francis

    Professor Doris Wilflingseder

  76. Antibodies attenuate the capacity of dendritic cells to stimulate HIV-specific cytotoxic T lymphocytes

    Article • Journal of Allergy and Clinical Immunology, December 2012, Elsevier

    Professor Doris Wilflingseder

  77. Article • Extremophiles, January 2012, The Feinstein Institute for Medical Research (North Shore LIJ Research Institute)

    Professor Doris Wilflingseder

  78. Innate Immune Responses in HIV-Infection

    Article • November 2011, IntechOpen

    Professor Doris Wilflingseder

  79. Pseudotyping Vesicular Stomatitis Virus with Lymphocytic Choriomeningitis Virus Glycoproteins Enhances Infectivity for Glioma Cells and Minimizes Neurotropism

    Article • Journal of Virology, March 2011, ASM Journals

    Professor Doris Wilflingseder

  80. Complement as an Endogenous Adjuvant for Dendritic Cell-Mediated Induction of Retrovirus-Specific CTLs

    Article • PLoS Pathogens, April 2010, PLOS

    Professor Doris Wilflingseder

  81. Induction of complement-mediated lysis of HIV-1 by a combination of HIV-specific and HLA allotype-specific antibodies

    Article • Immunology Letters, September 2009, Elsevier

    Professor Doris Wilflingseder

  82. Role of complement and antibodies in controlling infection with pathogenic simian immunodeficiency virus (SIV) in macaques vaccinated with replication-deficient viral vectors

    Article • Retrovirology, June 2009, Springer Science + Business Media

    Professor Doris Wilflingseder

  83. Prolonged survival of vaccinated macaques after oral SIVmac239 challenge regardless of viremia control in the chronic phase

    Article • Vaccine, December 2008, Elsevier

    Professor Doris Wilflingseder

  84. Complement and antibodies: A dangerous liaison in HIV infection?

    Article • Vaccine, December 2008, Elsevier

    Professor Doris Wilflingseder

  85. Complement–HIV interactions during all steps of viral pathogenesis

    Article • Vaccine, June 2008, Elsevier

    Professor Doris Wilflingseder

  86. HIV-1 induced generation of C5a attracts immature dendriticcells and promotes infection of autologous T cells

    Article • European Journal of Immunology, August 2007, Wiley

    Professor Doris Wilflingseder

  87. IgG Opsonization of HIV Impedes Provirus Formation in and Infection of Dendritic Cells and Subsequent Long-Term Transfer to T Cells

    Article • The Journal of Immunology, June 2007, The American Association of Immunologists

    Professor Doris Wilflingseder

  88. Lack of microbial DNA in tissue specimens of patients with abdominal aortic aneurysms and positive Chlamydiales serology

    Article • European Journal of Clinical Microbiology & Infectious Diseases, January 2007, Springer Science + Business Media

    Professor Doris Wilflingseder, Michael Schirmer

  89. Float on: lipid rafts in the lifecycle of HIV

    Article • Frontiers in Bioscience, January 2007, Frontiers in Bioscience

    Professor Doris Wilflingseder

  90. Factor I-Mediated Processing of Complement Fragments on HIV Immune Complexes Targets HIV to CR2-Expressing B Cells and Facilitates B Cell-Mediated Transmission of Opsonized HIV to T Cells

    Article • The Journal of Immunology, August 2006, The American Association of Immunologists

    Professor Doris Wilflingseder

  91. Reduction of viral loads by multigenic DNA priming and adenovirus boosting in the SIVmac-macaque model

    Article • Vaccine, March 2006, Elsevier

    Professor Doris Wilflingseder, Professor Jonathan Luke Heeney

  92. C-type lectin-independent interaction of complement opsonized HIV with monocyte-derived dendritic cells

    Article • European Journal of Immunology, September 2005, Wiley

    Professor Doris Wilflingseder

  93. Complement dependent trapping of infectious HIV in human lymphoid tissues

    Article • AIDS, March 2005, Wolters Kluwer Health

    Professor Doris Wilflingseder

  94. Mechanisms promoting dendritic cell-mediated transmission of HIV

    Article • Molecular Immunology, February 2005, Elsevier

    Professor Doris Wilflingseder

  95. HIV-1-Induced Migration of Monocyte-Derived Dendritic Cells Is Associated with Differential Activation of MAPK Pathways

    Article • The Journal of Immunology, December 2004, The American Association of Immunologists

    Professor Doris Wilflingseder

  96. Mechanism(s) promoting HIV-1 infection of primary unstimulated T lymphocytes in autologous B cell/T cell co-cultures

    Article • European Journal of Immunology, August 2003, Wiley

    Professor Doris Wilflingseder

  97. Cross-Linking of CD32 Induces Maturation of Human Monocyte-Derived Dendritic Cells Via NF- B Signaling Pathway

    Article • The Journal of Immunology, April 2003, The American Association of Immunologists

    Professor Doris Wilflingseder

  98. Complement-Mediated Enhancement of HIV-1 Neutralisation by Anti-HLA Antibodies Derived from Polytransfused Patients

    Article • International Archives of Allergy and Immunology, January 2003, Karger Publishers

    Professor Doris Wilflingseder

  99. Inhibition of diamine oxidase activity by heparins

    Article • Inflammation Research, April 2000, Springer Science + Business Media

    Professor Doris Wilflingseder