All Stories

  1. Application of natural language processing to predict diagnosis and treatments for 540 pediatric diseases based on 85,087 Electronic health records

    Article • Biomedical Signal Processing and Control, October 2026, Elsevier

    Dr. Hui-Qi Qu

  2. Drug repurposing opportunities across 92 CNS-related conditions using deep learning and whole-genome sequencing

    Article • Neurotherapeutics, September 2026, Elsevier

    Dr. Hui-Qi Qu

  3. Development and application of type 1 diabetes polygenic scores across diverse populations

    Article • Diabetologia, August 2026, Springer Science + Business Media

    Dr. Hui-Qi Qu

  4. SYCP3 enhances prostate cancer metastasis and modulates the DNA damage response pathway

    Article • Scientific Reports, August 2026, Springer Science + Business Media

    Dr. Hui-Qi Qu

  5. Shared genetic architecture and therapeutic targets across paediatric immune-mediated diseases

    Article • Annals of the Rheumatic Diseases, August 2026, Elsevier

    Dr. Hui-Qi Qu

  6. Sex and Obesity Stratified Asthma GWAS in African and European Ancestry Populations

    Article • July 2026, openRxiv

    Dr. Hui-Qi Qu

  7. Neuroinflammation as a driver of Down syndrome-associated Alzheimer’s disease

    Article • Brain Behavior and Immunity, July 2026, Elsevier

    Dr. Hui-Qi Qu

  8. Genetic susceptibility shaped by biological state: beyond gene-environment interaction

    Article • Frontiers in Genetics, June 2026, Frontiers

    Dr. Hui-Qi Qu

  9. Unsupervised Deep Representation Learning and Probabilistic Clustering for the Systems-Level Discovery of Germline Mutation Signatures in Pediatric Cancers

    Article • Biomedicines, June 2026, MDPI AG

    Dr. Hui-Qi Qu

  10. Cross-Ancestry Remapping of the Chromosome 1q31 Th2 pathway-associated interval Refines an Asthma Association Signal in Patients with Steroid-Dependent Disease

    Article • May 2026, openRxiv

    Dr. Hui-Qi Qu

  11. SCOTCH: isoform-level characterization of gene expression through long-read single-cell RNA sequencing

    Article • Nature Communications, May 2026, Springer Science + Business Media

    Dr. Hui-Qi Qu

  12. Targeting glutamatergic pathways: genetic insights into comorbid neurodevelopmental disorders

    Article • Brain, May 2026, Oxford University Press (OUP)

    Dr. Hui-Qi Qu

  13. Emergence of a high-risk multidrug-resistant Acinetobacter baumannii clone ST697 in nosocomial settings

    Article • Microbiology Spectrum, April 2026, ASM Journals

    Dr. Hui-Qi Qu

  14. Convergent genetic pathways linking neuropsychiatric and ocular disorders in children

    Article • Journal of Child Psychology and Psychiatry, April 2026, Wiley

    Dr. Hui-Qi Qu

  15. Circulating amino acids and Type 2 diabetes in a Latin American population-based cohort

    Article • Cardiovascular Diabetology, March 2026, Springer Science + Business Media

    Dr. Hui-Qi Qu

  16. Vascular malformations of the head and neck and a molecularly guided precision therapy framework

    Article • Frontiers in Neurology, March 2026, Frontiers

    Dr. Hui-Qi Qu

  17. Development and validation of a trans-ancestry polygenic risk score for type 1 diabetes

    Article • Diabetologia, March 2026, Springer Science + Business Media

    Dr. Hui-Qi Qu

  18. Editorial: Insights in applied genetic epidemiology 2025

    Article • Frontiers in Genetics, February 2026, Frontiers

    Dr. Hui-Qi Qu

  19. Genetic susceptibility to PM2.5 exposure and transcriptional responses in pediatric asthma: insights from single-cell transcriptomics

    Article • Frontiers in Immunology, February 2026, Frontiers

    Dr. Hui-Qi Qu

  20. Sex specific genomic insights into type 1 diabetes through GWAS and single cell transcriptome analysis

    Article • Diabetes Research and Clinical Practice, February 2026, Elsevier

    Dr. Hui-Qi Qu

  21. Circulating amino acids and Type 2 diabetes in a Latin American Population-based cohort

    Article • January 2026, Springer Science + Business Media

    Dr. Hui-Qi Qu

  22. APOL1 kidney risk variants and outcomes in children with congenital anomalies of the kidney and urinary tract

    Article • Pediatric Nephrology, January 2026, Springer Science + Business Media

    Dr. Hui-Qi Qu, Prof Ana Cristina Simões e Silva

  23. Metabolic remodeling and the modulatory role of vitamin D deficiency in African American children and adolescents with obesity

    Article • International Journal of Obesity, January 2026, Springer Science + Business Media

    Dr. Hui-Qi Qu

  24. Single vs Dual Genetic Disease in Children with Congenital Anomalies and Solid Tumors

    Article • Genetics in Medicine Open, January 2026, Elsevier

    Dr. Hui-Qi Qu

  25. Redefining the role of the thiol-based agent N -acetylcysteine in human health and disease and elucidating potential advantages of its amide derivative

    Article • RSC Medicinal Chemistry, January 2026, Royal Society of Chemistry

    Dr. Hui-Qi Qu

  26. Unsupervised machine learning integrates genomic variants and EMR to unravel mechanisms of brain hemorrhage and epilepsy as early indicators of alzheimer’s in down syndrome

    Article • Alzheimer s Research & Therapy, December 2025, Springer Science + Business Media

    Dr. Hui-Qi Qu

  27. Pro‑inflammatory insulin‑resistant lipid phenotype in down syndrome identified by 1H‑NMR metabolomics in obesity-matched African‑American children and young adults

    Article • Scientific Reports, November 2025, Springer Science + Business Media

    Dr. Hui-Qi Qu

  28. CD71+ erythroid cell expansion in late‐onset systemic lupus erythematosus

    Article • Journal of Internal Medicine, October 2025, Wiley

    Dr. Hui-Qi Qu

  29. Sex as a modifier of genetic risk for type 1 diabetes

    Article • Diabetes Obesity and Metabolism, September 2025, Wiley

    Dr. Hui-Qi Qu

  30. Data-informed insights into sex differences in peripheral blood mononuclear cells from single-cell transcriptomics

    Article • Genes & Diseases, September 2025, Elsevier

    Dr. Hui-Qi Qu

  31. Poster 236: Genome-Wide Association Study of African and European Populations With Anterior Cruciate Ligament Injury

    Article • Orthopaedic Journal of Sports Medicine, September 2025, SAGE Publications

    Dr. Hui-Qi Qu

  32. Natural killer cell subpopulations in the peripheral blood of single ventricle/hypoplastic left heart syndrome patients via single-cell RNA sequencing

    Article • Experimental Biology and Medicine, August 2025, Frontiers

    Dr. Hui-Qi Qu

  33. Single‐Cell RNA Sequencing of Peripheral Blood Mononuclear Cells in Patients With Single Ventricle/Hypoplastic Left Heart Syndrome

    Article • The Journal of Gene Medicine, August 2025, Wiley

    Dr. Hui-Qi Qu

  34. The impact of prematurity on pediatric asthma morbidity and indices with environmental pollution and genetic susceptibility

    Article • Communications Medicine, July 2025, Springer Science + Business Media

    Dr. Hui-Qi Qu

  35. Sex Specific Genomic Insights into Type 1 Diabetes through GWAS and Single Cell Transcriptome Analysis

    Article • July 2025, Cold Spring Harbor Laboratory Press

    Dr. Hui-Qi Qu

  36. Clinical association between asthma and anxiety is unrelated to genetic risk factors

    Article • Journal of Investigative Medicine, July 2025, SAGE Publications

    Dr. Hui-Qi Qu

  37. Development and validation of a Trans-Ancestry polygenic risk score for Type 1 Diabetes

    Article • June 2025, Cold Spring Harbor Laboratory Press

    Dr. Hui-Qi Qu

  38. Deep learning algorithms reveal genomic markers for anxiety disorder in a large cohort of children with down syndrome

    Article • Molecular Psychiatry, May 2025, Springer Science + Business Media

    Dr. Hui-Qi Qu

  39. VCL/ICAM-1 pathway is associated with lung inflammatory damage in SARS-CoV-2 Omicron infection

    Article • Nature Communications, April 2025, Springer Science + Business Media

    Dr. Hui-Qi Qu

  40. Sex-specific spirometry effects of adult COPD polygenic score in children with asthma

    Article • Scientific Reports, April 2025, Springer Science + Business Media

    Dr. Hui-Qi Qu

  41. Risk of Alzheimer's disease in Down syndrome: Insights gained by multi‐omics

    Article • Alzheimer s & Dementia, April 2025, Wiley

    Dr. Hui-Qi Qu

  42. Genomic variation and impact on the proteins of Mpox virus

    Article • Journal of Infection, April 2025, Elsevier

    Dr. Hui-Qi Qu

  43. A molecular basis for milk allergen immune recognition in eosinophilic esophagitis

    Article • Journal of Allergy and Clinical Immunology, April 2025, Elsevier

    Dr. Hui-Qi Qu

  44. The genetic landscape of pediatric postural orthostatic tachycardia syndrome

    Article • Clinical Autonomic Research, February 2025, Springer Science + Business Media

    Dr. Hui-Qi Qu

  45. Characterization of a circulating milk-specific TCR clonotype in a child with EoE milk allergy

    Article • Journal of Allergy and Clinical Immunology, February 2025, Elsevier

    Dr. Hui-Qi Qu

  46. Genetic modifiers of asthma response to air pollution in children: An African ancestry GWAS and PM2.5 polygenic risk score study

    Article • Environmental Research, February 2025, Elsevier

    Dr. Hui-Qi Qu

  47. CRISPR screening reveals SYCP3 as a key driver of metastasis in prostate cancer

    Article • January 2025, Cold Spring Harbor Laboratory Press

    Dr. Hui-Qi Qu

  48. O57: Association of polygenic risk scores with disease prevalence in pediatrics: Insights into obesity, asthma, type 1 and type 2 diabetes

    Article • Genetics in Medicine Open, January 2025, Elsevier

    Dr. Hui-Qi Qu

  49. Rare variants in cardiomyopathy genes predispose to cardiac injury in severe COVID-19 patients of African or Hispanic ancestry

    Article • Journal of Molecular Medicine, December 2024, Springer Science + Business Media

    Dr. Hui-Qi Qu

  50. Genetic Association of Juvenile Idiopathic Arthritis With Adult Rheumatic Disease

    Article • JAMA Network Open, December 2024, American Medical Association (AMA)

    Dr. Hui-Qi Qu

  51. BAG3’s dual roles in Parkinson’s disease and cardiomyopathy: benefit or liability?

    Article • Acta Neuropathologica, November 2024, Springer Science + Business Media

    Dr. Hui-Qi Qu

  52. Companion to: A molecular basis for milk allergen immune recognition in eosinophilic esophagitis

    Article • November 2024, Cold Spring Harbor Laboratory Press

    Dr. Hui-Qi Qu

  53. Abstract 4140702: Sex Differences Revealed by Single Cell Transcriptome Analysis of Peripheral Blood Mononuclear Cells in Single Ventricle/Hypoplastic Left Heart Patients

    Article • Circulation, November 2024, Wolters Kluwer Health

    Dr. Hui-Qi Qu

  54. The Role of BAG3 Protein Interactions in Cardiomyopathies

    Article • International Journal of Molecular Sciences, October 2024, MDPI AG

    Dr. Hui-Qi Qu

  55. Deciphering protective genomic factors of tumor development in pediatric down syndrome via deep learning approach to whole genome and RNA sequencing

    Article • Cancer Communications, October 2024, Wiley

    Dr. Hui-Qi Qu

  56. Implications of the non‐neuronal cholinergic system for therapeutic interventions of inflammatory skin diseases

    Article • Experimental Dermatology, October 2024, Wiley

    Dr. Hui-Qi Qu

  57. Role ofBAG3protein interactions in cardiomyopathies

    Article • September 2024, Cold Spring Harbor Laboratory Press

    Dr. Hui-Qi Qu

  58. Navigating Complexity in Postural Orthostatic Tachycardia Syndrome

    Article • Biomedicines, August 2024, MDPI AG

    Dr. Hui-Qi Qu

  59. Single-cell RNA Sequencing of Peripheral Blood Mononuclear Cells in Patients with Single Ventricle/Hypoplastic Left Heart Syndrome

    Article • August 2024, Cold Spring Harbor Laboratory Press

    Dr. Hui-Qi Qu

  60. Characterization of Natural Killer Cell Subpopulations in the Blood of Single Ventricle/Hypoplastic Left Heart Syndrome Patients Using Single-Cell RNA Sequencing

    Article • August 2024, Cold Spring Harbor Laboratory Press

    Dr. Hui-Qi Qu

  61. Copy number variations contribute to malignant tumor development in children with serious birth defects

    Article • Molecular Oncology, August 2024, Wiley

    Dr. Hui-Qi Qu

  62. Emerging Role of Soluble Suppression of Tumorigenicity 2 as Biomarker for Acute Exacerbations in COPD Patients

    Article • August 2024, Springer Science + Business Media

    Dr. Hui-Qi Qu

  63. Shared molecular mechanisms and transdiagnostic potential of neurodevelopmental disorders and immune disorders

    Article • Brain Behavior and Immunity, July 2024, Elsevier

    Dr. Hui-Qi Qu

  64. Target genes regulated by CLEC16A intronic region associated with common variable immunodeficiency

    Article • Journal of Allergy and Clinical Immunology, June 2024, Elsevier

    Dr. Hui-Qi Qu

  65. The Genetic Landscape of Pediatric Postural Orthostatic Tachycardia Syndrome

    Article • May 2024, Cold Spring Harbor Laboratory Press

    Dr. Hui-Qi Qu

  66. Single-Cell Omics for Transcriptome CHaracterization (SCOTCH): isoform-level characterization of gene expression through long-read single-cell RNA sequencing

    Article • April 2024, Cold Spring Harbor Laboratory Press

    Dr. Hui-Qi Qu

  67. CRISPR/Cas9 screenings unearth protein arginine methyltransferase 7 as a novel essential gene in prostate cancer metastasis

    Article • Cancer Letters, April 2024, Elsevier

    Dr. Hui-Qi Qu

  68. NASP gene contributes to autism by epigenetic dysregulation of neural and immune pathways

    Article • Journal of Medical Genetics, March 2024, BMJ

    Dr. Hui-Qi Qu

  69. Revealing novel genomic insights and therapeutic targets for juvenile idiopathic arthritis through omics

    Article • Rheumatology, February 2024, Oxford University Press (OUP)

    Dr. Hui-Qi Qu

  70. Central Conducting Lymphatic Anomalies

    Article • January 2024, Springer Science + Business Media

    Dr. Hui-Qi Qu

  71. Mitochondrial DNA Haplogroup K Is Protective of Autism Spectrum Disorder Risk in Populations of European Ancestry

    Article • Journal of the American Academy of Child & Adolescent Psychiatry, December 2023, Elsevier

    Dr. Hui-Qi Qu

  72. Single-Cell RNA Sequencing Technologies

    Article • Stem Cells, November 2023, Oxford University Press (OUP)

    Dr. Hui-Qi Qu

  73. Children with Birth Defects Have a Higher Risk of Cancer: Learning from an In-Depth CNV Analysis

    Article • Translational Research, November 2023, Elsevier

    Dr. Hui-Qi Qu

  74. A Protective Role of Low Polygenic Risk Score in Healthy Individuals Carrying Attention-Deficit/Hyperactivity Disorder–Associated Copy Number Variations

    Article • Biological Psychiatry, October 2023, Elsevier

    Dr. Hui-Qi Qu

  75. The Circassians and the Chechens in Jordan: results of a decade of epidemiological and genetic studies

    Article • Journal of Community Genetics, September 2023, Springer Science + Business Media

    Dr. Hui-Qi Qu

  76. Genomic information of children with malignant brain tumors for the prediction of length of hospitalization

    Article • Cancer Communications, August 2023, Wiley

    Dr. Hui-Qi Qu

  77. Genomic variants exclusively identified in children with birth defects and concurrent malignant tumors predispose to cancer development

    Article • Molecular Cancer, August 2023, Springer Science + Business Media

    Dr. Hui-Qi Qu

  78. Genetic Scores for Body Weight

    Article • Clinical and Translational Discovery, August 2023, Wiley

    Dr. Hui-Qi Qu

  79. CRISPR/Cas9 screenings unearth protein arginine methyltransferase 7 as a novel driver of metastasis in prostate cancer

    Article • July 2023, Cold Spring Harbor Laboratory Press

    Dr. Hui-Qi Qu

  80. Using Genetic Information to Predict Alzheimer's Disease Risk Across Different Ethnicities

    Article • Alzheimer s & Dementia, July 2023, Wiley

    Dr. Hui-Qi Qu

  81. Trans-ethnic Polygenic Risk Scores for Body Mass Index

    Article • Clinical and Translational Medicine, June 2023, Wiley

    Dr. Hui-Qi Qu

  82. TOPORS as a novel causal gene for Joubert syndrome

    Article • American Journal of Medical Genetics Part A, May 2023, Wiley

    Dr. Hui-Qi Qu

  83. Precision Medicine

    Article • JACC Heart Failure, April 2023, Elsevier

    Dr. Hui-Qi Qu

  84. Identification of copy number variants contributing to hallux valgus

    Article • Frontiers in Genetics, March 2023, Frontiers

    Dr. Hui-Qi Qu

  85. BAG3: Nature’s Quintessential Multi-Functional Protein Functions as a Ubiquitous Intra-Cellular Glue

    Article • Cells, March 2023, MDPI AG

    Dr. Hui-Qi Qu

  86. Genome-wide association study of the age of onset of type 1 diabetes reveals HTATIP2 as a novel T cell regulator

    Article • Frontiers in Immunology, February 2023, Frontiers

    Dr. Hui-Qi Qu

  87. International Study on Polygenic Risk Scores for Body Weight Across Different Ethnic Groups

    Article • January 2023, Cold Spring Harbor Laboratory Press

    Dr. Hui-Qi Qu

  88. Single Cell RNAseq of Peripheral Blood Mononuclear Cells from Fresh and Stored Blood Samples

    Article • Genes, January 2023, MDPI AG

    Dr. Hui-Qi Qu

  89. Trans-ethnic Genomic Informed Risk Assessment for Alzheimer’s disease: An International Hundred K+ Cohorts Consortium Study

    Article • December 2022, Cold Spring Harbor Laboratory Press

    Dr. Hui-Qi Qu

  90. Understanding BAG3 Gene for Creating Targeted Treatments for Dilated Cardiomyopathies

    Article • Journal of the American Heart Association, December 2022, Wolters Kluwer Health

    Dr. Hui-Qi Qu

  91. Metabolomic profiling for dyslipidemia in pediatric patients with sickle cell disease, on behalf of the IHCC consortium

    Article • Metabolomics, December 2022, Springer Science + Business Media

    Dr. Hui-Qi Qu

  92. Identification of risk variants related to malignant tumors in children with birth defects by whole genome sequencing

    Article • Biomarker Research, November 2022, Springer Science + Business Media

    Dr. Hui-Qi Qu

  93. Genetic architecture of asthma in African American patients

    Article • Journal of Allergy and Clinical Immunology, September 2022, Elsevier

    Dr. Hui-Qi Qu

  94. COVID-19 in pediatrics: Genetic susceptibility

    Article • Frontiers in Genetics, August 2022, Frontiers

    Dr. Hui-Qi Qu

  95. Identification of novel loci in obstructive sleep apnea in European American and African American children

    Article • SLEEP, July 2022, Oxford University Press (OUP)

    Dr. Hui-Qi Qu

  96. Identification of Novel Loci Shared by Juvenile Idiopathic Arthritis Subtypes Through Integrative Genetic Analysis

    Article • Arthritis & Rheumatology, July 2022, Wiley

    Dr. Hui-Qi Qu

  97. Metabolomic profiling of samples from pediatric patients with asthma unveils deficient nutrients in African Americans

    Article • iScience, July 2022, Elsevier

    Dr. Hui-Qi Qu

  98. Mutation burden analysis of six common mental disorders in African Americans by whole genome sequencing

    Article • Human Molecular Genetics, June 2022, Oxford University Press (OUP)

    Dr. Hui-Qi Qu

  99. Burden of rare coding variants reveals genetic heterogeneity between obese and non-obese asthma patients in the African American population

    Article • May 2022, Springer Science + Business Media

    Dr. Hui-Qi Qu

  100. Mendelian randomization study of obesity and type 2 diabetes in hospitalized COVID-19 patients

    Article • Metabolism, April 2022, Elsevier

    Dr. Hui-Qi Qu

  101. Expansion of Schizophrenia Gene Network Knowledge Using Machine Learning Selected Signals From Dorsolateral Prefrontal Cortex and Amygdala RNA-seq Data

    Article • Frontiers in Psychiatry, March 2022, Frontiers

    Dr. Hui-Qi Qu

  102. A genome-wide association meta-analysis identifies new eosinophilic esophagitis loci

    Article • Journal of Allergy and Clinical Immunology, March 2022, Elsevier

    Dr. Hui-Qi Qu

  103. Genetic analysis for type 1 diabetes genes in juvenile dermatomyositis unveils genetic disease overlap

    Article • Rheumatology, February 2022, Oxford University Press (OUP)

    Dr. Hui-Qi Qu

  104. Identification of Mitochondrial DNA Variants Associated With Risk of Neuroblastoma

    Article • JNCI Journal of the National Cancer Institute, February 2022, Oxford University Press (OUP)

    Dr. Hui-Qi Qu

  105. Circulating LIGHT (TNFSF14) and Interleukin-18 Levels in Sepsis-Induced Multi-Organ Injuries

    Article • Biomedicines, January 2022, MDPI AG

    Dr. Hui-Qi Qu

  106. Improved genetic risk scoring algorithm for type 1 diabetes prediction

    Article • Pediatric Diabetes, January 2022, Hindawi Publishing Corporation

    Dr. Hui-Qi Qu

  107. Application of deep learning algorithm on whole genome sequencing data uncovers structural variants associated with multiple mental disorders in African American patients

    Article • Molecular Psychiatry, January 2022, Springer Science + Business Media

    Dr. Hui-Qi Qu

  108. Corrigendum

    Article • FEBS Letters, November 2021, Wiley

    Dr. Hui-Qi Qu

  109. Insights into non-autoimmune type 1 diabetes with 13 novel loci in low polygenic risk score patients

    Article • Scientific Reports, August 2021, Springer Science + Business Media

    Dr. Hui-Qi Qu

  110. Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci

    Article • Communications Biology, July 2021, Springer Science + Business Media

    Dr. Hui-Qi Qu

  111. Deep learning prediction of attention-deficit hyperactivity disorder in African Americans by copy number variation

    Article • Experimental Biology and Medicine, July 2021, SAGE Publications

    Dr. Hui-Qi Qu

  112. Abstract 2310: Identification of novel essential genes for prostate cancer metastasis by genome scale CRISPR approaches

    Article • Cancer Research, July 2021, American Association for Cancer Research (AACR)

    Dr. Hui-Qi Qu

  113. Combined application of genetic and polygenic risk scores for type 1 diabetes risk prediction

    Article • Diabetes Obesity and Metabolism, June 2021, Wiley

    Dr. Hui-Qi Qu

  114. Elevation of Circulating LIGHT (TNFSF14) and Interleukin-18 Levels in Sepsis-Induced Multi-Organ Injuries

    Article • May 2021, Cold Spring Harbor Laboratory Press

    Dr. Hui-Qi Qu

  115. Serum levels of the IgA isotype switch factor TGF‐β1 are elevated in patients with COVID‐19

    Article • FEBS Letters, May 2021, Wiley

    Dr. Hui-Qi Qu

  116. Metabolomic profiling of anaerobic and aerobic energy metabolic pathways in chronic obstructive pulmonary disease

    Article • Experimental Biology and Medicine, May 2021, SAGE Publications

    Dr. Hui-Qi Qu

  117. Genetic correlations between COVID-19 and a variety of traits and diseases

    Article • The Innovation, May 2021, Elsevier

    Dr. Hui-Qi Qu

  118. New insights into hallux valgus by whole exome sequencing study

    Article • Experimental Biology and Medicine, April 2021, SAGE Publications

    Dr. Hui-Qi Qu

  119. Machine Learning Reduced Gene/Non-Coding RNA Features That Classify Schizophrenia Patients Accurately and Highlight Insightful Gene Clusters

    Article • International Journal of Molecular Sciences, March 2021, MDPI AG

    Dr. Hui-Qi Qu

  120. Rare Recurrent Variants in Noncoding Regions Impact Attention-Deficit Hyperactivity Disorder (ADHD) Gene Networks in Children of both African American and European American Ancestry

    Article • Genes, February 2021, MDPI AG

    Dr. Hui-Qi Qu

  121. FLNC and MYLK2 Gene Mutations in a Chinese Family with Different Phenotypes of Cardiomyopathy

    Article • International Heart Journal, January 2021, International Heart Journal (Japanese Heart Journal)

    Dr. Hui-Qi Qu

  122. Association of novel rare coding variants with juvenile idiopathic arthritis

    Article • Annals of the Rheumatic Diseases, January 2021, BMJ

    Dr. Hui-Qi Qu

  123. DLL1 and type 1 diabetes with less prominent autoimmune response

    Article • Metabolism, January 2021, Elsevier

    Dr. Hui-Qi Qu

  124. Genetic correlations between COVID-19 and a variety of traits and diseases

    Article • December 2020, Cold Spring Harbor Laboratory Press

    Dr. Hui-Qi Qu

  125. Interpretation of Maturity-Onset Diabetes of the Young Genetic Variants Based on American College of Medical Genetics and Genomics Criteria: Machine-Learning Model Development

    Article • JMIR Biomedical Engineering, December 2020, JMIR Publications Inc.

    Dr. Hui-Qi Qu

  126. Heparin-binding protein and aggravation/multi-organ damage in severe COVID-19

    Article • ERJ Open Research, November 2020, European Respiratory Society (ERS)

    Dr. Hui-Qi Qu, Mingshan Xue

  127. Mitochondrial DNA haplogroups and risk of attention deficit and hyperactivity disorder in European Americans

    Article • Translational Psychiatry, November 2020, Springer Science + Business Media

    Dr. Hui-Qi Qu

  128. COVID-19: Look to the Future, Learn from the Past

    Article • Viruses, October 2020, MDPI AG

    Dr. Hui-Qi Qu

  129. Expression Pattern of the SARS-CoV-2 Entry Genes ACE2 and TMPRSS2 in the Respiratory Tract

    Article • Viruses, October 2020, MDPI AG

    Dr. Hui-Qi Qu

  130. The Multi-Omics Architecture of Juvenile Idiopathic Arthritis

    Article • Cells, October 2020, MDPI AG

    Dr. Hui-Qi Qu

  131. Genetics of Low Polygenic Risk Score Type 1 Diabetes Patients: rare variants in 22 novel loci

    Article • October 2020, Cold Spring Harbor Laboratory Press

    Dr. Hui-Qi Qu

  132. Non-coding structural variation differentially impacts attention-deficit hyperactivity disorder (ADHD) gene networks in African American vs Caucasian children

    Article • Scientific Reports, September 2020, Springer Science + Business Media

    Dr. Hui-Qi Qu

  133. Integrative Genetics Analysis of Juvenile Idiopathic Arthritis Identifies Novel Loci

    Article • September 2020, Cold Spring Harbor Laboratory Press

    Dr. Hui-Qi Qu

  134. The Infection Rate of COVID-19 in Wuhan, China: Combined Analysis of Population Samples

    Article • Journal of Medical Internet Research, August 2020, JMIR Publications Inc.

    Dr. Hui-Qi Qu

  135. High prevalence of elevated serum liver enzymes in Chinese children suggests metabolic syndrome as a common risk factor

    Article • Journal of Paediatrics and Child Health, August 2020, Wiley

    Dr. Hui-Qi Qu

  136. Machine learning reduced gene/non-coding RNA features that classify Schizophrenia patients accurately and highlight insightful gene clusters

    Article • June 2020, Cold Spring Harbor Laboratory Press

    Dr. Hui-Qi Qu

  137. FLNC and MYLK2 gene mutations in a Chinese family with different phenotypes of cardiomyopathy

    Article • May 2020, Cold Spring Harbor Laboratory Press

    Dr. Hui-Qi Qu

  138. Distinct features of SARS-CoV-2-specific IgA response in COVID-19 patients

    Article • European Respiratory Journal, May 2020, European Respiratory Society (ERS)

    Dr. Hui-Qi Qu

  139. Liraglutide Ameliorates Lipotoxicity-Induced Oxidative Stress by Activating the NRF2 Pathway in HepG2 Cells

    Article • Hormone and Metabolic Research, May 2020, Thieme Publishing Group

    Dr. Hui-Qi Qu

  140. Role of the ADCY9 gene in cardiac abnormalities of the Rubinstein-Taybi syndrome

    Article • Orphanet Journal of Rare Diseases, April 2020, Springer Science + Business Media

    Dr. Hui-Qi Qu

  141. Mitochondrial DNA Haplogroups and Susceptibility to Neuroblastoma

    Article • JNCI Journal of the National Cancer Institute, February 2020, Oxford University Press (OUP)

    Dr. Hui-Qi Qu

  142. Rare Genetic Variants of Large Effect Influence Risk of Type 1 Diabetes

    Article • Diabetes, January 2020, American Diabetes Association

    Tomoko Nakanishi, Dr. Hui-Qi Qu

  143. Association of Rare Recurrent Copy Number Variants With Congenital Heart Defects Based on Next-Generation Sequencing Data From Family Trios

    Article • Frontiers in Genetics, September 2019, Frontiers

    Dr. Hui-Qi Qu

  144. Application of ACMG criteria to classify variants in the human gene mutation database

    Article • Journal of Human Genetics, August 2019, Springer Science + Business Media

    Dr. Hui-Qi Qu

  145. Metabolomics study in COPD

    Article • International Journal of Chronic Obstructive Pulmonary Disease, August 2019, Dove Medical Press

    Xiqing Bian, Haisheng Hu, Dr. Hui-Qi Qu, Mingshan Xue

  146. Value of immune factors for monitoring risk of lung cancer in patients with interstitial lung disease

    Article • Journal of International Medical Research, July 2019, SAGE Publications

    Dr. Hui-Qi Qu

  147. Microduplications at the 15q11.2 BP1–BP2 locus are enriched in patients with anorexia nervosa

    Article • Journal of Psychiatric Research, June 2019, Elsevier

    Dr. Hui-Qi Qu

  148. Effects of Intranasal Cellulose Powder on Asthma Control in Children With Mild-to-Moderate Perennial Allergic Rhinitis: A Randomized, Placebo-Controlled Trial

    Article • American Journal of Rhinology and Allergy, February 2019, SAGE Publications

    Dr. Hui-Qi Qu

  149. Entropy change of biological dynamics in COPD

    Article • International Journal of Chronic Obstructive Pulmonary Disease, October 2017, Dove Medical Press

    Dr. Hui-Qi Qu

  150. Nonfunctional pancreatic endocrine tumor in the peripancreatic region in a Chinese patient with multiple endocrine neoplasia type 1

    Article • Journal of International Medical Research, September 2017, SAGE Publications

    Dr. Hui-Qi Qu

  151. Effect of hypercortisolism on bone mineral density and bone metabolism: A potential protective effect of adrenocorticotropic hormone in patients with Cushing’s disease

    Article • Journal of International Medical Research, August 2017, SAGE Publications

    Dr. Hui-Qi Qu

  152. Active form of vitamin D ameliorates non-alcoholic fatty liver disease by alleviating oxidative stress in a high-fat diet rat model

    Article • Endocrine Journal, January 2017, Japan Endocrine Society

    Dr. Hui-Qi Qu

  153. A novel AVPR2 gene mutation of X-linked congenital nephrogenic diabetes insipidus in an Asian pedigree

    Article • Journal of International Medical Research, September 2016, SAGE Publications

    Dr. Hui-Qi Qu

  154. 1,25(OH)2D3 downregulates the Toll-like receptor 4-mediated inflammatory pathway and ameliorates liver injury in diabetic rats

    Article • Journal of Endocrinological Investigation, April 2015, Springer Science + Business Media

    Dr. Hui-Qi Qu

  155. Clostridium difficile infection in diabetes

    Article • Diabetes Research and Clinical Practice, September 2014, Elsevier

    Dr. Hui-Qi Qu

  156. Gene-Specific Function Prediction for Non-Synonymous Mutations in Monogenic Diabetes Genes

    Article • PLOS One, August 2014, PLOS

    Dr. Hui-Qi Qu

  157. Genome-wide search for exonic variants affecting translational efficiency

    Article • Nature Communications, July 2013, Springer Science + Business Media

    Dr. Hui-Qi Qu

  158. A case report of syndrome of inappropriate antidiuretic hormone secretion with Castleman’s disease and lymphoma

    Article • BMC Endocrine Disorders, June 2013, Springer Science + Business Media

    Dr. Hui-Qi Qu

  159. Human Coding Synonymous Single Nucleotide Polymorphisms at Ramp Regions of mRNA Translation

    Article • PLOS One, March 2013, PLOS

    Dr. Hui-Qi Qu

  160. Ancestral Effect on HOMA-IR Levels Quantitated in an American Population of Mexican Origin

    Article • Diabetes Care, August 2012, American Diabetes Association

    Dr. Hui-Qi Qu

  161. PNPLA3 Polymorphisms and Liver Aminotransferase Levels in a Mexican American Population

    Article • Clinical & Investigative Medicine, August 2012, University of Toronto Libraries - UOTL

    Dr. Hui-Qi Qu

  162. Population-based Risk Factors for Elevated Alanine Aminotransferase in a South Texas Mexican–American Population

    Article • Archives of Medical Research, August 2012, Elsevier

    Dr. Hui-Qi Qu

  163. Screening for novel lead compounds increasing insulin expression in medullary thymic epithelial cells

    Article • European Journal of Pharmacology, August 2012, Elsevier

    Dr. Hui-Qi Qu

  164. Association Between CASP8 and CASP10 Polymorphisms and Toxicity Outcomes With Platinum‐Based Chemotherapy in Chinese Patients With Non‐Small Cell Lung Cancer

    Article • The Oncologist, July 2012, Wiley

    Dr. Hui-Qi Qu

  165. Translational genomic medicine: common metabolic traits and ancestral components of Mexican Americans

    Article • Journal of Medical Genetics, June 2012, BMJ

    Dr. Hui-Qi Qu

  166. Ancestry Informative Marker Set for Han Chinese Population

    Article • G3 Genes Genomes Genetics, March 2012, Genetics Society of America

    Dr. Hui-Qi Qu

  167. Host susceptibility to tuberculosis: insights from a longitudinal study of gene expression in diabetes [Short communication]

    Article • The International Journal of Tuberculosis and Lung Disease, March 2012, International Union Against Tuberculosis and Lung Disease

    Dr. Hui-Qi Qu

  168. Adiponectin/leptin ratio and Metabolic Syndrome in a Mexican American population

    Article • Clinical & Investigative Medicine, October 2011, University of Toronto Libraries - UOTL

    Dr. Hui-Qi Qu

  169. A Genome-Wide Meta-Analysis of Six Type 1 Diabetes Cohorts Identifies Multiple Associated Loci

    Article • PLoS Genetics, September 2011, PLOS

    Dr. Hui-Qi Qu

  170. Decreased expression of ATP6V1H in type 2 diabetes: A pilot report on the diabetes risk study in Mexican Americans

    Article • Biochemical and Biophysical Research Communications, September 2011, Elsevier

    Dr. Hui-Qi Qu

  171. Association Study of Candidate Gene Polymorphisms and Obesity in a Young Mexican-American Population from South Texas

    Article • Archives of Medical Research, August 2011, Elsevier

    Dr. Hui-Qi Qu

  172. Prevalence of Metabolic Syndrome and Risks of Abnormal Serum Alanine Aminotransferase in Hispanics: A Population-Based Study

    Article • PLOS One, June 2011, PLOS

    Dr. Hui-Qi Qu

  173. The Definition of Insulin Resistance Using HOMA-IR for Americans of Mexican Descent Using Machine Learning

    Article • PLOS One, June 2011, PLOS

    Dr. Hui-Qi Qu

  174. Molecular immunity to mycobacteria: knowledge from the mutation and phenotype spectrum analysis of Mendelian susceptibility to mycobacterial diseases

    Article • International Journal of Infectious Diseases, May 2011, Elsevier

    Dr. Hui-Qi Qu

  175. What did we learn from the genome-wide association study for tuberculosis susceptibility?

    Article • Journal of Medical Genetics, January 2011, BMJ

    Dr. Hui-Qi Qu

  176. Knowledge gaining by human genetic studies on tuberculosis susceptibility

    Article • Journal of Human Genetics, December 2010, Springer Science + Business Media

    Dr. Hui-Qi Qu

  177. In silico replication of the genome-wide association results of the Type 1 Diabetes Genetics Consortium

    Article • Human Molecular Genetics, April 2010, Oxford University Press (OUP)

    Dr. Hui-Qi Qu

  178. Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects

    Article • Human Molecular Genetics, February 2010, Oxford University Press (OUP)

    Dr. Hui-Qi Qu

  179. Genome-wide profiling using single-nucleotide polymorphism arrays identifies novel chromosomal imbalances in pediatric glioblastomas

    Article • Neuro-Oncology, February 2010, Oxford University Press (OUP)

    Dr. Hui-Qi Qu

  180. Rfx6 directs islet formation and insulin production in mice and humans

    Article • Nature, February 2010, Springer Science + Business Media

    Dr. Hui-Qi Qu

  181. Reassessment of the type I diabetes association of the OAS1 locus

    Article • Genes & Immunity, December 2009, Springer Science + Business Media

    Dr. Hui-Qi Qu

  182. Remapping the type I diabetes association of the CTLA4 locus

    Article • Genes & Immunity, December 2009, Springer Science + Business Media

    Dr. Hui-Qi Qu

  183. The type I diabetes association of the IL2RA locus

    Article • Genes & Immunity, December 2009, Springer Science + Business Media

    Dr. Hui-Qi Qu

  184. From Disease Association to Risk Assessment: An Optimistic View from Genome-Wide Association Studies on Type 1 Diabetes

    Article • PLoS Genetics, October 2009, PLOS

    Dr. Hui-Qi Qu

  185. A cis-Acting Regulatory Variant in the IL2RA Locus

    Article • The Journal of Immunology, September 2009, The American Association of Immunologists

    Dr. Hui-Qi Qu

  186. Association of RASGRP1 with type 1 diabetes is revealed by combined follow-up of two genome-wide studies

    Article • Journal of Medical Genetics, May 2009, BMJ

    Dr. Hui-Qi Qu

  187. The effect of the MHC locus on autoantibodies in type 1 diabetes

    Article • Journal of Medical Genetics, May 2009, BMJ

    Dr. Hui-Qi Qu

  188. Identification of susceptibility genes for complex diseases using pooling-based genome-wide association scans

    Article • Human Genetics, January 2009, Springer Science + Business Media

    Dr. Hui-Qi Qu

  189. The Genetic Basis of Diabetes

    Article • January 2009, Springer Science + Business Media

    Dr. Hui-Qi Qu

  190. Follow-Up Analysis of Genome-Wide Association Data Identifies Novel Loci for Type 1 Diabetes

    Article • Diabetes, October 2008, American Diabetes Association

    Dr. Hui-Qi Qu

  191. Association Analysis of Type 2 Diabetes Loci in Type 1 Diabetes

    Article • Diabetes, April 2008, American Diabetes Association

    Dr. Hui-Qi Qu

  192. The association between type 1 diabetes and the ITPR3 gene polymorphism due to linkage disequilibrium with HLA class II

    Article • Genes & Immunity, March 2008, Springer Science + Business Media

    Dr. Hui-Qi Qu

  193. A Novel Susceptibility Locus for Type 1 Diabetes on Chr12q13 Identified by a Genome-Wide Association Study

    Article • Diabetes, January 2008, American Diabetes Association

    Dr. Hui-Qi Qu

  194. The association between the IFIH1 locus and type 1 diabetes

    Article • Diabetologia, December 2007, Springer Science + Business Media

    Dr. Hui-Qi Qu

  195. The IRF5 polymorphism in type 1 diabetes

    Article • Journal of Medical Genetics, October 2007, BMJ

    Dr. Hui-Qi Qu

  196. The TCF7L2locus and type 1 diabetes

    Article • BMC Medical Genetics, August 2007, Springer Science + Business Media

    Dr. Hui-Qi Qu

  197. A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene

    Article • Nature, July 2007, Springer Science + Business Media

    Dr. Hui-Qi Qu

  198. A Common Variant of the PAX2 Gene Is Associated with Reduced Newborn Kidney Size

    Article • Journal of the American Society of Nephrology, May 2007, American Society of Nephrology

    Dr. Hui-Qi Qu

  199. Toward Further Mapping of the Association Between the IL2RA Locus and Type 1 Diabetes

    Article • Diabetes, March 2007, American Diabetes Association

    Dr. Hui-Qi Qu

  200. No association of type 1 diabetes with a functional polymorphism of the LRAP gene

    Article • Molecular Immunology, March 2007, Elsevier

    Dr. Hui-Qi Qu

  201. Genetic Control of Alternative Splicing in the TAP2 Gene: Possible Implication in the Genetics of Type 1 Diabetes

    Article • Diabetes, December 2006, American Diabetes Association

    Dr. Hui-Qi Qu

  202. Strand bias in complementary single-nucleotide polymorphisms of transcribed human sequences: evidence for functional effects of synonymous polymorphisms

    Article • BMC Genomics, August 2006, Springer Science + Business Media

    Dr. Hui-Qi Qu

  203. Lack of association of type 1 diabetes with the IL4R gene

    Article • Diabetologia, March 2006, Springer Science + Business Media

    Dr. Hui-Qi Qu

  204. Type 1 diabetes and the OAS gene cluster: association with splicing polymorphism or haplotype?

    Article • Journal of Medical Genetics, June 2005, BMJ

    Dr. Hui-Qi Qu

  205. Confirmation of the association of the R620W polymorphism in the protein tyrosine phosphatase PTPN22 with type 1 diabetes in a family based study

    Article • Journal of Medical Genetics, March 2005, BMJ

    Dr. Hui-Qi Qu

  206. Assessing the validity of the association between the SUMO4 M55V variant and risk of type 1 diabetes

    Article • Nature Genetics, February 2005, Springer Science + Business Media

    Dr. Hui-Qi Qu

  207. Restless Legs Syndrome (RLS) in Uremic Patients Is Related to the Frequency of Hemodialysis Sessions

    Article • January 2000, Karger Publishers

    Dr. Hui-Qi Qu