All Stories

  1. The role of shear micromotion on bone ingrowth into a three-dimensional porous scaffold predicted by a mechanoregulatary finite element model

    Article • Computer Methods in Biomechanics & Biomedical Engineering, June 2025, Taylor & Francis

    Professor Glen L Niebur

  2. Osteocytes respond to bone deformation

    Article • Scientific Reports, May 2025, Springer Science + Business Media

    Professor Glen L Niebur

  3. Controlled mechanical loading affects the osteocyte transcriptome in porcine trabecular bone in situ

    Article • Bone, April 2024, Elsevier

    Professor Glen L Niebur

  4. Defects affect the fatigue behavior of additively manufactured titanium

    Article • Additive Manufacturing, April 2022, Elsevier

    Professor Glen L Niebur

  5. Integration of mechanics and biology in computer simulation of bone remodeling

    Article • Progress in Biophysics and Molecular Biology, September 2021, Elsevier

    Professor Glen L Niebur

  6. Triple negative breast cancer cells migrate toward bone marrow by targeting leptin

    Article • Molecular Biology of the Cell, May 2021, American Society for Cell Biology (ASCB)

    Professor Glen L Niebur

  7. Cancer spheroids grow more slowly in stiff gelatin culture

    Article • Journal of The Royal Society Interface, December 2020, Royal Society Publishing

    Professor Glen L Niebur

  8. Future Prospects and Challenges

    Article • January 2020, Elsevier

    Professor Glen L Niebur

  9. Mechanobiology

    Article • January 2020, Elsevier

    Professor Glen L Niebur

  10. Mineral deposition and vascular invasion of hydroxyapatite reinforced collagen scaffolds seeded with human adipose-derived stem cells

    Article • Biomaterials Research, October 2019, American Association for the Advancement of Science

    Professor Glen L Niebur

  11. The CXCL5/CXCR2 axis is sufficient to promote breast cancer colonization during bone metastasis

    Article • Nature Communications, September 2019, Springer Science + Business Media

    Professor Glen L Niebur

  12. Effects of mechanobiological signaling in bone marrow on skeletal health

    Article • Annals of the New York Academy of Sciences, September 2019, Wiley

    Professor Glen L Niebur

  13. Shear Stress in Bone Marrow has a Dose Dependent Effect on cFos Gene Expression in In Situ Culture

    Article • Cellular and Molecular Bioengineering, August 2019, Springer Science + Business Media

    Professor Glen L Niebur

  14. Mineral deposition and vascular invasion of hydroxyapatite reinforced collagen scaffolds seeded with human adipose-derived stem cells

    Article • July 2019, Cold Spring Harbor Laboratory Press

    Professor Glen L Niebur

  15. Potassium channel activity controls breast cancer metastasis by affecting β-catenin signaling

    Article • Cell Death and Disease, February 2019, Springer Science + Business Media

    Professor Glen L Niebur

  16. Abstract 56: CXCL5 is a master regulator of the dormancy switch to activate metastatic colonization of dormant breast cancer cells during bone metastasis

    Article • Cancer Research, July 2018, American Association for Cancer Research (AACR)

    Professor Glen L Niebur

  17. Bone marrow cells respond to mechanical stimuli to induce bone formation.

    Article • Bone, February 2018, Elsevier

    Professor Glen L Niebur

  18. Bone: A Fertile Soil for Cancer Metastasis

    Article • Current Drug Targets, August 2017, Bentham Science Publishers

    Professor Glen L Niebur

  19. Intraoperative biomechanics of lumbar pedicle screw loosening following successful arthrodesis

    Article • Journal of Orthopaedic Research®, July 2017, Wiley

    Professor Glen L Niebur

  20. Mechanically induced bone formation is not sensitive to local osteocyte density in rat vertebral cancellous bone

    Article • Journal of Orthopaedic Research®, June 2017, Wiley

    Professor Glen L Niebur

  21. Erratum to: Anisotropic Permeability of Trabecular Bone and Its Relationship to Fabric and Architecture: A Computational Study

    Article • Annals of Biomedical Engineering, April 2017, Springer Science + Business Media

    Professor Glen L Niebur

  22. Three-dimensional printing of X-ray computed tomography datasets with multiple materials using open-source data processing

    Article • Anatomical Sciences Education, February 2017, Wiley

    Professor Glen L Niebur

  23. Anisotropic Permeability of Trabecular Bone and its Relationship to Fabric and Architecture: A Computational Study

    Article • Annals of Biomedical Engineering, February 2017, Springer Science + Business Media

    Professor Glen L Niebur

  24. Altered architecture and cell populations affect bone marrow mechanobiology in the osteoporotic human femur

    Article • Biomechanics and Modeling in Mechanobiology, November 2016, Springer Science + Business Media

    Professor Glen L Niebur

  25. Comparison of solid and fluid constitutive models of bone marrow during trabecular bone compression

    Article • Journal of Biomechanics, October 2016, Elsevier

    Professor Glen L Niebur

  26. The roles of architecture and estrogen depletion in microdamage risk in trabecular bone

    Article • Journal of Biomechanics, October 2016, Elsevier

    Professor Glen L Niebur

  27. Primary cilia expression in bone marrow in response to mechanical stimulation in explant bioreactor culture

    Article • July 2016, Forum Multimedia Publishing LLC

    Professor Glen L Niebur

  28. Pressure and shear stress in trabecular bone marrow during whole bone loading

    Article • Journal of Biomechanics, September 2015, Elsevier

    Professor Glen L Niebur

  29. On the influence of marrow on the mechanical behavior of porcine trabecular bone under dynamic loading: a numerical investigation

    Article • Computer Methods in Biomechanics & Biomedical Engineering, August 2015, Taylor & Francis

    Professor Glen L Niebur

  30. An Experimental and Computational Investigation of Bone Formation in Mechanically Loaded Trabecular Bone Explants

    Article • Annals of Biomedical Engineering, July 2015, Springer Science + Business Media

    Professor Glen L Niebur

  31. Development of an in vivo rabbit ulnar loading model

    Article • Bone, June 2015, Elsevier

    Professor Glen L Niebur

  32. The sensitivity of nonlinear computational models of trabecular bone to tissue level constitutive model

    Article • Computer Methods in Biomechanics & Biomedical Engineering, May 2015, Taylor & Francis

    Professor Glen L Niebur

  33. Hydroxyapatite reinforced collagen scaffolds with improved architecture and mechanical properties

    Article • Acta Biomaterialia, April 2015, Elsevier

    Professor Glen L Niebur

  34. The In Situ Mechanics of Trabecular Bone Marrow: The Potential for Mechanobiological Response

    Article • Journal of Biomechanical Engineering, December 2014, ASME International

    Professor Glen L Niebur

  35. Multiscale Modeling of Trabecular Bone Marrow: Understanding the Micromechanical Environment of Mesenchymal Stem Cells During Osteoporosis

    Article • Journal of Biomechanical Engineering, December 2014, ASME International

    Professor Glen L Niebur

  36. Rheological behavior of fresh bone marrow and the effects of storage

    Article • Journal of the Mechanical Behavior of Biomedical Materials, December 2014, Elsevier

    Professor Glen L Niebur

  37. Primary Cilia Exist in a Small Fraction of Cells in Trabecular Bone and Marrow

    Article • Calcified Tissue International, November 2014, Springer Science + Business Media

    Professor Glen L Niebur

  38. Mechanical Stimulation of Bone Marrow In Situ Induces Bone Formation in Trabecular Explants

    Article • Annals of Biomedical Engineering, October 2014, Springer Science + Business Media

    Professor Glen L Niebur

  39. Characterization of cancellous and cortical bone strain in the in vivo mouse tibial loading model using microCT-based finite element analysis

    Article • Bone, September 2014, Elsevier

    Professor Glen L Niebur

  40. Alterations in trabecular bone microarchitecture in the ovine spine and distal femur following ovariectomy

    Article • Journal of Biomechanics, June 2014, Elsevier

    Professor Glen L Niebur

  41. How Bone Tissue and Cells Experience Elevated Temperatures During Orthopaedic Cutting: An Experimental and Computational Investigation

    Article • Journal of Biomechanical Engineering, February 2014, ASME International

    Professor Glen L Niebur

  42. A probabilistic damage model based on direct 3-D correlation of strain to damage formation following fatigue loading of rat femora

    Article • Journal of the Mechanical Behavior of Biomedical Materials, February 2014, Elsevier

    Professor Glen L Niebur

  43. Biomedical Modeling: The Role of Transport and Mechanics

    Article • The Bulletin of Mathematical Biophysics, July 2013, Springer Science + Business Media

    Professor Glen L Niebur

  44. In vivo microdamage is an indicator of susceptibility to initiation and propagation of microdamage in human femoral trabecular bone

    Article • Bone, July 2013, Elsevier

    Professor Glen L Niebur

  45. Computational Modelling of the Mechanics of Trabecular Bone and Marrow Using Fluid Structure Interaction Techniques

    Article • Annals of Biomedical Engineering, December 2012, Springer Science + Business Media

    Professor Glen L Niebur

  46. The relative influence of apatite crystal orientations and intracortical porosity on the elastic anisotropy of human cortical bone

    Article • Journal of Biomechanics, November 2012, Elsevier

    Professor Glen L Niebur

  47. Fluid shear stress in trabecular bone marrow due to low-magnitude high-frequency vibration

    Article • Journal of Biomechanics, August 2012, Elsevier

    Professor Glen L Niebur

  48. Osteogenic differentiation of mesenchymal stem cells is regulated by osteocyte and osteoblast cells in a simplified bone niche

    Article • January 2012, Forum Multimedia Publishing LLC

    Professor Glen L Niebur

  49. Indentation experiments and simulation of ovine bone using a viscoelastic-plastic damage model

    Article • Journal of Materials Research, November 2011, Cambridge University Press

    Professor Glen L Niebur

  50. Viscoelastic properties of human cortical bone tissue depend on gender and elastic modulus

    Article • Journal of Orthopaedic Research®, November 2011, Wiley

    Professor Glen L Niebur

  51. Shear strength and toughness of trabecular bone are more sensitive to density than damage

    Article • Journal of Biomechanics, November 2011, Elsevier

    Professor Glen L Niebur

  52. Direct comparison of nanoindentation and macroscopic measurements of bone viscoelasticity

    Article • Journal of the Mechanical Behavior of Biomedical Materials, November 2011, Elsevier

    Professor Glen L Niebur

  53. Detection of fatigue microdamage in whole rat femora using contrast-enhanced micro-computed tomography

    Article • Journal of Biomechanics, September 2011, Elsevier

    Professor Glen L Niebur

  54. Response to Letter to the Editor from David P. Fyhrie

    Article • Journal of Biomechanics, September 2011, Elsevier

    Professor Glen L Niebur

  55. Shear Stress Within Trabecular Bone Marrow due to Low Magnitude High Frequency Vibration

    Article • June 2011, ASME International

    Professor Glen L Niebur

  56. The effect of holding time on nanoindentation measurements of creep in bone

    Article • Journal of Biomechanics, April 2011, Elsevier

    Professor Glen L Niebur

  57. Contrast-enhanced micro-computed tomography of fatigue microdamage accumulation in human cortical bone

    Article • Bone, March 2011, Elsevier

    Professor Glen L Niebur

  58. Type and orientation of yielded trabeculae during overloading of trabecular bone along orthogonal directions

    Article • Journal of Biomechanics, September 2010, Elsevier

    Professor Glen L Niebur

  59. High Fidelity Computational Model of Bone Remodeling Cellular Mechanisms

    Article • June 2010, ASME International

    Professor Glen L Niebur

  60. Effects of trabecular type and orientation on microdamage susceptibility in trabecular bone

    Article • Bone, May 2010, Elsevier

    Professor Glen L Niebur

  61. Improved accuracy of cortical bone mineralization measured by polychromatic microcomputed tomography using a novel high mineral density composite calibration phantom

    Article • Medical Physics, January 2010, American Association of Physicists in Medicine (AAPM)

    Professor Glen L Niebur

  62. High Strain Rate Testing of Bovine Trabecular Bone

    Article • Journal of Biomechanical Engineering, January 2010, ASME International

    Professor Glen L Niebur

  63. Signaling Pathways for Bone Resorption Predicted as a Hybrid Cellular Automaton Process

    Article • January 2010, ASME International

    Professor Glen L Niebur

  64. Computational Modeling of Trabecular Bone Mechanics

    Article • November 2009, Springer Science + Business Media

    Professor Glen L Niebur

  65. A semi-automated method for hexahedral mesh construction of human vertebrae from CT scans

    Article • Computer Methods in Biomechanics & Biomedical Engineering, October 2009, Taylor & Francis

    Professor Glen L Niebur

  66. Effect of the Vitamin D Receptor on Bone Geometry and Strength During Gestation and Lactation in Mice

    Article • Calcified Tissue International, September 2009, Springer Science + Business Media

    Professor Glen L Niebur

  67. Density and architecture have greater effects on the toughness of trabecular bone than damage

    Article • Bone, May 2009, Elsevier

    Professor Glen L Niebur

  68. Effects of Loading Orientation on the Morphology of the Predicted Yielded Regions in Trabecular Bone

    Article • Annals of Biomedical Engineering, December 2008, Springer Science + Business Media

    Professor Glen L Niebur

  69. Micro-computed tomography of fatigue microdamage in cortical bone using a barium sulfate contrast agent

    Article • Journal of the Mechanical Behavior of Biomedical Materials, January 2008, Elsevier

    Professor Glen L Niebur

  70. Mechanical property determination of bone through nano- and micro-indentation testing and finite element simulation

    Article • Journal of Biomechanics, January 2008, Elsevier

    Professor Glen L Niebur

  71. Compressive properties of trabecular bone in the distal femur

    Article • Journal of Biomechanics, January 2008, Elsevier

    Professor Glen L Niebur

  72. A fully anisotropic hierarchical hybrid cellular automaton algorithm to simulate bone remodeling

    Article • Mechanics Research Communications, January 2008, Elsevier

    Professor Glen L Niebur

  73. Bone ingrowth into a porous coated implant predicted by a mechano-regulatory tissue differentiation algorithm

    Article • Biomechanics and Modeling in Mechanobiology, August 2007, Springer Science + Business Media

    Professor Glen L Niebur

  74. Investigation of Osteoclast Resorption Mechanisms in a Hybrid Cellular Automaton Model of Bone Remodeling

    Article • June 2007, ASME International

    Professor Glen L Niebur

  75. Prediction of Mechanical Properties of Vertebral Trabecular Bone Using Microstructural Finite Element Models

    Article • June 2007, ASME International

    Professor Glen L Niebur

  76. Detection of trabecular bone microdamage by micro-computed tomography

    Article • Journal of Biomechanics, January 2007, Elsevier

    Professor Glen L Niebur

  77. Topology Optimization Using a Hybrid Cellular Automaton Method With Local Control Rules

    Article • Journal of Mechanical Design, January 2006, ASME International

    Professor Glen L Niebur

  78. Microdamage propagation in trabecular bone due to changes in loading mode

    Article • Journal of Biomechanics, January 2006, Elsevier

    Professor Glen L Niebur

  79. Axial-shear interaction effects on microdamage in bovine tibial trabecular bone

    Article • European Journal of Morphology, April 2005, Portico

    Professor Glen L Niebur

  80. Fatigue Microdamage in Bovine Cortical Bone Imaged by Micro-Computed Tomography Using a Barium Sulfate Contrast Agent

    Article • MRS Proceedings, January 2005, Springer Science + Business Media

    Professor Glen L Niebur

  81. Bone Structure Adaptation as a Cellular Automaton Optimization Process

    Article • April 2004, American Institute of Aeronautics and Astronautics (AIAA)

    Professor Glen L Niebur

  82. Preparation of On-Axis Cylindrical Trabecular Bone Specimens Using Micro-CT Imaging

    Article • Journal of Biomechanical Engineering, March 2004, ASME International

    Professor Glen L Niebur

  83. Comparison of the elastic and yield properties of human femoral trabecular and cortical bone tissue

    Article • Journal of Biomechanics, January 2004, Elsevier

    Professor Glen L Niebur

  84. Effects of damage on the orthotropic material symmetry of bovine tibial trabecular bone

    Article • Journal of Biomechanics, December 2003, Elsevier

    Professor Glen L Niebur

  85. Biomechanical effects of intraspecimen variations in tissue modulus for trabecular bone

    Article • Journal of Biomechanics, February 2002, Elsevier

    Professor Glen L Niebur

  86. Biaxial Failure Behavior of Bovine Tibial Trabecular Bone

    Article • Journal of Biomechanical Engineering, January 2002, ASME International

    Professor Glen L Niebur

  87. A Grammar Driven Data Translation System for Computer Integrated Manufacturing

    Article • Journal of Mechanical Design, January 2002, ASME International

    Professor Glen L Niebur

  88. Biomechanics of Trabecular Bone

    Article • Annual Review of Biomedical Engineering, August 2001, Annual Reviews

    Professor Glen L Niebur

  89. Sensitivity of damage predictions to tissue level yield properties and apparent loading conditions

    Article • Journal of Biomechanics, May 2001, Elsevier

    Professor Glen L Niebur

  90. High-resolution finite element models with tissue strength asymmetry accurately predict failure of trabecular bone

    Article • Journal of Biomechanics, December 2000, Elsevier

    Professor Glen L Niebur

  91. Damage Behavior of Trabecular Bone

    Article • November 2000, ASME International

    Professor Glen L Niebur

  92. The relevance of the moment arm of shoulder muscles with respect to axial rotation of the glenohumeral joint in four positions

    Article • Clinical Biomechanics, June 2000, Elsevier

    Professor Glen L Niebur

  93. Kinematics of the proximal interphalangeal joint of the finger after surface replacement

    Article • The Journal Of Hand Surgery, March 2000, Elsevier

    Professor Glen L Niebur

  94. Simulation of Trabecular Bone Yield Using Nonlinear Finite Element Analysis

    Article • November 1999, ASME International

    Professor Glen L Niebur

  95. LIGAMENT LENGTH DURING CIRCUMDUCTION OF THE TRAPEZIOMETACARPAL JOINT AFTER LIGAMENT SECTIONING

    Article • Journal of Musculoskeletal Research, September 1999, World Scientific Pub Co Pte Lt

    Professor Glen L Niebur

  96. Article • The Journal Of Hand Surgery, May 1999, Elsevier

    Professor Glen L Niebur

  97. Biomechanical analysis of the trapeziometacarpal joint after surface replacement arthroplasty

    Article • The Journal Of Hand Surgery, May 1999, Elsevier

    Professor Glen L Niebur

  98. The effects of wrist distraction on carpal kinematics

    Article • The Journal Of Hand Surgery, January 1999, Elsevier

    Professor Glen L Niebur

  99. Convergence Behavior of High-Resolution Finite Element Models of Trabecular Bone

    Article • Journal of Biomechanical Engineering, January 1999, ASME International

    Professor Glen L Niebur

  100. Convergence Characteristics of Voxel Based Finite Element Models of Trabecular Bone

    Article • November 1998, ASME International

    Professor Glen L Niebur

  101. Mechanical advantage of the thumb muscles

    Article • Journal of Biomechanics, June 1998, Elsevier

    Professor Glen L Niebur

  102. Feasibility of using a magnetic tracking device for measuring carpal kinematics

    Article • Journal of Biomechanics, November 1997, Elsevier

    Professor Glen L Niebur

  103. Ligament length during circumduction of the trapeziometacarpal joint

    Article • Journal of Orthopaedic Science, September 1997, Elsevier

    Professor Glen L Niebur

  104. Comparison of two methods for computing abduction moment arms of the rotator cuff

    Article • Journal of Biomechanics, May 1997, Elsevier

    Professor Glen L Niebur

  105. Roles of deltoid and rotator cuff muscles in shoulder elevation

    Article • Clinical Biomechanics, January 1997, Elsevier

    Professor Glen L Niebur

  106. A Grammar Driven Data Translation System for Computer Integrated Manufacturing

    Article • August 1996, ASME International

    Professor Glen L Niebur

  107. Kinematics of the trapeziometacarpal joint: A biomechanical analysis comparing tendon interposition arthroplasty and total-joint arthroplasty

    Article • The Journal Of Hand Surgery, July 1996, Elsevier

    Professor Glen L Niebur

  108. Determination of the proximity tolerance for measurement of surface contact areas using a magnetic tracking device

    Article • Journal of Biomechanics, March 1996, Elsevier

    Professor Glen L Niebur

  109. Malrotation of the humeral component of the capitellocondylar total elbow replacement is not the sole cause of dislocation

    Article • Journal of Orthopaedic Research®, September 1994, Wiley

    Professor Glen L Niebur

  110. Motion and laxity of the capitellocondylar total elbow prosthesis.

    Article • Journal of Bone and Joint Surgery, July 1994, Wolters Kluwer Health

    Professor Glen L Niebur

  111. Kinematics of the trapeziometacarpal joint after sectioning of ligaments

    Article • Journal of Orthopaedic Research®, March 1994, Wiley

    Professor Glen L Niebur

  112. Kinematics of the normal trapeziometacarpal joint

    Article • Journal of Orthopaedic Research®, March 1994, Wiley

    Professor Glen L Niebur

  113. Kinematics and stability of the Norway elbow: A cadaveric study

    Article • Acta Orthopaedica Scandinavica, January 1993, Taylor & Francis

    Professor Glen L Niebur