All Stories

  1. Adaptive DNA amplification of synthetic gene circuit opens a way to overcome cancer chemoresistance

    Article • Proceedings of the National Academy of Sciences, November 2023, Proceedings of the National Academy of Sciences

    Gabor Balazsi

  2. Transcriptional drift in aging cells: A global de-controller

    Article • November 2023, Cold Spring Harbor Laboratory Press

    Gabor Balazsi

  3. Cusp bifurcation in a metastatic regulatory network

    Article • Journal of Theoretical Biology, November 2023, Elsevier

    Gabor Balazsi

  4. MaxCal can infer models from coupled stochastic trajectories of gene expression and cell division

    Article • Biophysical Journal, July 2023, Elsevier

    Gabor Balazsi

  5. Immune mechanisms shape the clonal landscape during early progression of prostate cancer

    Article • Developmental Cell, June 2023, Elsevier

    Gabor Balazsi

  6. Nonmonotone invasion landscape by noise-aware control of metastasis activator levels

    Article • Nature Chemical Biology, May 2023, Springer Science + Business Media

    Gabor Balazsi

  7. Analysis of Gene Expression Heterogeneity Reveals Therapeutic Targets and Novel Regulators of Metastasis

    Article • December 2022, Cold Spring Harbor Laboratory Press

    Gabor Balazsi

  8. New antivirals exploit viral feedback tricks for a cure without resistance

    Article • Cell, June 2022, Elsevier

    Gabor Balazsi

  9. Drug-dependent growth curve reshaping reveals mechanisms of antifungal resistance in Saccharomyces cerevisiae

    Article • Communications Biology, March 2022, Springer Science + Business Media

    Gabor Balazsi

  10. Nonmonotone invasion landscape by engineered control of metastasis activator levels

    Article • March 2022, Research Square

    Gabor Balazsi

  11. What differentiates a stress response from responsiveness in general?

    Article • Cell Systems, March 2022, Elsevier

    Gabor Balazsi

  12. Gene-circuit therapy on the horizon: synthetic biology tools for engineered therapeutics

    Article • Acta Biochimica Polonica, August 2021, Frontiers

    Gabor Balazsi

  13. Reliably Engineering and Controlling Stable Optogenetic Gene Circuits in Mammalian Cells

    Article • Journal of Visualized Experiments, July 2021, MyJove Corporation

    Gabor Balazsi

  14. From Bench to Keyboard and Back Again: A Brief History of Lambda Phage Modeling

    Article • Annual Review of Biophysics, May 2021, Annual Reviews

    Gabor Balazsi

  15. Discovering evolutionary hidden treasures

    Article • Nature Computational Science, January 2021, Springer Science + Business Media

    Gabor Balazsi

  16. Observation and Control of Gene Expression Noise: Barrier Crossing Analogies Between Drug Resistance and Metastasis

    Article • Frontiers in Genetics, October 2020, Frontiers

    Gabor Balazsi

  17. How Do Cells Adapt? Stories Told in Landscapes

    Article • Annual Review of Chemical and Biomolecular Engineering, June 2020, Annual Reviews

    Gabor Balazsi

  18. Binary Expression Enhances Reliability of Messaging in Gene Networks

    Article • Entropy, April 2020, MDPI AG

    Gabor Balazsi

  19. Multiplexed Gene Expression Tuning with Orthogonal Synthetic Gene Circuits

    Article • ACS Synthetic Biology, March 2020, American Chemical Society (ACS)

    Gabor Balazsi

  20. Bursty Expression Enhances Reliability of Messaging in Gene Networks

    Article • February 2020, Cold Spring Harbor Laboratory Press

    Gabor Balazsi

  21. Diversity in lac Operon Regulation among Diverse Escherichia coli Isolates Depends on the Broader Genetic Background but Is Not Explained by Genetic Relatedness

    Article • mBio, December 2019, ASM Journals

    Gabor Balazsi

  22. Optimality of the spontaneous prophage induction rate

    Article • Journal of Theoretical Biology, December 2019, Elsevier

    Gabor Balazsi

  23. Evolutionary regain of lost gene circuit function

    Article • Proceedings of the National Academy of Sciences, November 2019, Proceedings of the National Academy of Sciences

    Gabor Balazsi

  24. Evolutionary regain of lost gene circuit function

    Article • October 2019, Cold Spring Harbor Laboratory Press

    Gabor Balazsi

  25. Disadvantages and benefits of evolved unicellularity versus multicellularity in budding yeast

    Article • Ecology and Evolution, July 2019, Wiley

    Gabor Balazsi

  26. Noise-reducing optogenetic negative-feedback gene circuits in human cells

    Article • Nucleic Acids Research, July 2019, Oxford University Press (OUP)

    Gabor Balazsi

  27. Role of network-mediated stochasticity in mammalian drug resistance

    Article • Nature Communications, June 2019, Springer Science + Business Media

    Dr Daniel Charlebois, Gabor Balazsi

  28. Modeling cell population dynamics

    Article • In Silico Biology, May 2019, IOS Press

    Dr Daniel Charlebois, Gabor Balazsi

  29. Towards control of cellular decision-making networks in the epithelial-to-mesenchymal transition

    Article • Physical Biology, March 2019, Institute of Physics Publishing

    Gabor Balazsi

  30. Transferring information without distortion

    Article • eLife, October 2018, eLife

    Gabor Balazsi

  31. Multiscale effects of heating and cooling on genes and gene networks

    Article • Proceedings of the National Academy of Sciences, October 2018, Proceedings of the National Academy of Sciences

    Dr Daniel Charlebois, Gabor Balazsi

  32. Beyond Promoters: How Genes Tweak Their Own Expression

    Article • Trends in Genetics, October 2018, Elsevier

    Gabor Balazsi

  33. A landscape view on the interplay between EMT and cancer metastasis

    Article • npj Systems Biology and Applications, August 2018, Springer Science + Business Media

    Gabor Balazsi

  34. Coupling of DNA Replication and Negative Feedback Controls Gene Expression for Cell-Fate Decisions

    Article • iScience, August 2018, Elsevier

    Gabor Balazsi

  35. Evolutionary trade-offs between unicellularity and multicellularity in budding yeast

    Article • June 2018, Cold Spring Harbor Laboratory Press

    Gabor Balazsi

  36. Negative Regulation Gene Circuits for Efflux Pump Control

    Article • January 2018, Springer Science + Business Media

    Dr Daniel Charlebois, Gabor Balazsi

  37. Building Predictive Models of Genetic Circuits Using the Principle of Maximum Caliber

    Article • Biophysical Journal, November 2017, Elsevier

    Gabor Balazsi

  38. Late-Arriving Signals Contribute Less to Cell-Fate Decisions

    Article • Biophysical Journal, November 2017, Elsevier

    Gabor Balazsi

  39. Functional effects of heating and cooling gene networks

    Article • August 2017, Cold Spring Harbor Laboratory Press

    Gabor Balazsi

  40. Generational distribution of a Candida glabrata population: Resilient old cells prevail, while younger cells dominate in the vulnerable host

    Article • PLoS Pathogens, May 2017, PLOS

    Gabor Balazsi

  41. Phenotypic heterogeneity promotes adaptive evolution

    Article • PLoS Biology, May 2017, PLOS

    Gabor Balazsi

  42. Cell fate decisions emerge as phages cooperate or compete inside their host

    Article • Nature Communications, February 2017, Nature

    Gabor Balazsi

  43. Lysis‐lysogeny coexistence: prophage integration during lytic development

    Article • MicrobiologyOpen, August 2016, Wiley

    Gabor Balazsi

  44. Frequency‐dependent selection: a diversifying force in microbial populations

    Article • Molecular Systems Biology, August 2016, EMBO

    Dr Daniel Charlebois, Gabor Balazsi

  45. Efflux Pump Control Alters Synthetic Gene Circuit Function

    Article • ACS Synthetic Biology, July 2016, American Chemical Society (ACS)

    Dr Daniel Charlebois, Gabor Balazsi

  46. Reconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis

    Article • Nature Communications, March 2016, Springer Science + Business Media

    Gabor Balazsi

  47. Cellular Growth Arrest and Persistence from Enzyme Saturation

    Article • PLoS Computational Biology, March 2016, PLOS

    Gabor Balazsi

  48. Optimality and adaptation of phenotypically switching cells in fluctuating environments

    Article • Physical Review E, December 2015, American Physical Society (APS)

    Gabor Balazsi

  49. Gene networks evolve predictably over short times.

    Article • Molecular Systems Biology, August 2015, EMBO

    Gabor Balazsi

  50. Two-Dimensionality of Yeast Colony Expansion Accompanied by Pattern Formation

    Article • PLoS Computational Biology, December 2014, PLOS

    Gabor Balazsi

  51. Coherent feedforward transcriptional regulatory motifs enhance drug resistance

    Article • Physical Review E, May 2014, American Physical Society (APS)

    Dr Daniel Charlebois, Gabor Balazsi

  52. Unraveling the regulatory connections between two controllers of breast cancer cell fate

    Article • Nucleic Acids Research, May 2014, Oxford University Press (OUP)

    Gabor Balazsi

  53. Network of mutually repressive metastasis regulators can promote cell heterogeneity and metastatic transitions

    Article • Proceedings of the National Academy of Sciences, January 2014, Proceedings of the National Academy of Sciences

    Prof Eun-jin Kim, Gabor Balazsi

  54. Moving a synthetic gene circuit from yeast cells into cancer cells.

    Article • Nature Communications, February 2013, Nature

    Gabor Balazsi

  55. Genome-Wide Discovery of Small RNAs in Mycobacterium tuberculosis

    Article • PLoS ONE, December 2012, PLOS

    Paolo Miotto, Gabor Balazsi

  56. Abortive Autophagy Induces Endoplasmic Reticulum Stress and Cell Death in Cancer Cells

    Article • PLoS ONE, June 2012, PLOS

    Gabor Balazsi

  57. Linking the Transcriptional Profiles and the Physiological States of Mycobacterium tuberculosis during an Extended Intracellular Infection

    Article • PLoS Pathogens, June 2012, PLOS

    Gabor Balazsi

  58. Mapping the Environmental Fitness Landscape of a Synthetic Gene Circuit

    Article • PLoS Computational Biology, April 2012, PLOS

    Gabor Balazsi

  59. A network-based, integrative study to identify core biological pathways that drive breast cancer clinical subtypes

    Article • British Journal of Cancer, February 2012, Springer Science + Business Media

    Gabor Balazsi

  60. Adaptive Evolution of the Lactose Utilization Network in Experimentally Evolved Populations of Escherichia coli

    Article • PLoS Genetics, January 2012, PLOS

    Gabor Balazsi

  61. A common repressor pool results in indeterminacy of extrinsic noise

    Article • Chaos An Interdisciplinary Journal of Nonlinear Science, December 2011, American Institute of Physics

    Gabor Balazsi

  62. Kinome siRNA-phosphoproteomic screen identifies networks regulating AKT signaling

    Article • Oncogene, June 2011, Springer Science + Business Media

    Gabor Balazsi

  63. Cellular Decision Making and Biological Noise: From Microbes to Mammals

    Article • Cell, March 2011, Elsevier

    Gabor Balazsi

  64. Linearizer Gene Circuits with Negative Feedback Regulation

    Article • January 2011, Springer Science + Business Media

    Gabor Balazsi

  65. Regulation of Central Metabolism Genes of Mycobacterium tuberculosis by Parallel Feed-Forward Loops Controlled by Sigma Factor E ( E)

    Article • Journal of Bacteriology, December 2010, ASM Journals

    Gabor Balazsi

  66. The interplay of multiple feedback loops with post-translational kinetics results in bistability of mycobacterial stress response

    Article • Physical Biology, August 2010, Institute of Physics Publishing

    Gabor Balazsi

  67. Network reconstruction reveals new links between aging and calorie restriction in yeast

    Article • HFSP Journal, June 2010, Taylor & Francis

    Gabor Balazsi

  68. Tuning and controlling gene expression noise in synthetic gene networks

    Article • Nucleic Acids Research, March 2010, Oxford University Press (OUP)

    Gabor Balazsi

  69. Network inference and network response identification: moving genome-scale data to the next level of biological discovery

    Article • Molecular BioSystems, January 2010, Royal Society of Chemistry

    Gabor Balazsi

  70. Adaptive-Control Model for Neutrophil Orientation in the Direction of Chemical Gradients

    Article • Biophysical Journal, May 2009, Elsevier

    Gabor Balazsi

  71. Negative autoregulation linearizes the dose–response and suppresses the heterogeneity of gene expression

    Article • Proceedings of the National Academy of Sciences, March 2009, Proceedings of the National Academy of Sciences

    Gabor Balazsi

  72. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest

    Article • Molecular Systems Biology, November 2008, EMBO

    Gabor Balazsi

  73. Bipolarity of the Saccharomyces Cerevisiae Genome

    Article • May 2008, Institute of Electrical & Electronics Engineers (IEEE)

    Professor Lydia E Kavraki, Gabor Balazsi

  74. A Semi-Supervised Method for Predicting Transcription Factor–Gene Interactions in Escherichia coli

    Article • PLoS Computational Biology, March 2008, PLOS

    Gabor Balazsi

  75. Combinatorial promoter design for engineering noisy gene expression

    Article • Proceedings of the National Academy of Sciences, July 2007, Proceedings of the National Academy of Sciences

    Gabor Balazsi

  76. Planktonic copepods reacting selectively to hydrodynamic disturbances

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, May 2007, Royal Society Publishing

    Gabor Balazsi

  77. Taking the inventory inside single cells

    Article • Nature Chemical Biology, March 2007, Springer Science + Business Media

    Gabor Balazsi

  78. Phenotypic Consequences of Promoter-Mediated Transcriptional Noise

    Article • Molecular Cell, December 2006, Elsevier

    Gabor Balazsi

  79. Topological units of environmental signal processing in the transcriptional regulatory network of Escherichia coli

    Article • Proceedings of the National Academy of Sciences, May 2005, Proceedings of the National Academy of Sciences

    Gabor Balazsi

  80. Genome-scale identification of conditionally essential genes in E. coli by DNA microarrays

    Article • Biochemical and Biophysical Research Communications, September 2004, Elsevier

    Gabor Balazsi

  81. Experimental Determination and System Level Analysis of Essential Genes in Escherichia coli MG1655

    Article • Journal of Bacteriology, October 2003, ASM Journals

    Dr Nikos C Kyrpides, Withmore Williams Associate Professor Erzsébet Regan, Gabor Balazsi

  82. Spurious spatial periodicity of co-expression in microarray data due to printing design

    Article • Nucleic Acids Research, August 2003, Oxford University Press (OUP)

    Gabor Balazsi

  83. Pattern formation and stochastic motion of the zooplankton Daphnia in a light field

    Article • Physica A Statistical Mechanics and its Applications, July 2003, Elsevier

    Gabor Balazsi

  84. Increased phase synchronization of spontaneous calcium oscillations in epileptic human versus normal rat astrocyte cultures

    Article • Chaos An Interdisciplinary Journal of Nonlinear Science, June 2003, American Institute of Physics

    Gabor Balazsi

  85. Daphnia swarms: from single agent dynamics to collective vortex formation

    Article • May 2003, SPIE

    Gabor Balazsi

  86. Organization of Work via a Natural Substance: Regulation of Nest Construction in Social Wasps

    Article • Journal of Theoretical Biology, October 2002, Elsevier

    Gabor Balazsi

  87. Synchronization of hyperexcitable systems with phase-repulsive coupling

    Article • September 2001, American Physical Society (APS)

    Gabor Balazsi

  88. Spatiotemporal stochastic resonance and its consequences in neural model systems

    Article • Chaos An Interdisciplinary Journal of Nonlinear Science, September 2001, American Institute of Physics

    Gabor Balazsi

  89. From stochastic resonance to brain waves

    Article • Physics Letters A, January 2000, Elsevier

    Gabor Balazsi

  90. A Pitfall in Series of Microarrays: The Position of Probes Affects the Cross-Correlation of Gene Expression Profiles

    Article • Springer Science + Business Media

    Gabor Balazsi