All Stories

  1. Membrane Binding of Hydrophobic Ions: Application of New Kinetic Techniques

    Article • Langmuir, March 2025, American Chemical Society (ACS)

    Dr Francesco Tadini-Buoninsegni

  2. Photodynamic Inactivation of the Sarcoplasmic Reticulum Ca2+‐ATPase by a Ruthenium Polypyridyl Complex Featuring π‐Expansive Ligands

    Article • Bioinorganic Chemistry and Applications, January 2025, Wiley

    Dr Francesco Tadini-Buoninsegni

  3. On the track of the lipid transport pathway of the phospholipid flippase ATP8A2 - Mutation analysis of residues of the transmembrane segments M1, M2, M3 and M4

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, January 2024, Elsevier

    Dr Francesco Tadini-Buoninsegni

  4. Development of a flow system for decentralized electrochemical analysis of heavy metals using screen-printed electrodes: the importance of sensor stability

    Article • The Analyst, January 2024, Royal Society of Chemistry

    Dr Francesco Tadini-Buoninsegni

  5. A bioelectrochemical approach based on a solid supported membrane to evaluate the effect of natural products on Ca2+-ATPase: The case of 6-gingerol

    Article • Electrochimica Acta, August 2023, Elsevier

    Dr Francesco Tadini-Buoninsegni

  6. Electrogenic reaction step and phospholipid translocation pathway of the mammalian P4‐ATPase ATP8A2

    Article • FEBS Letters, August 2022, Wiley

    Dr Francesco Tadini-Buoninsegni

  7. Stimulation of Ca 2+ ‐ATPase Transport Activity by a Small‐Molecule Drug

    Article • ChemMedChem, August 2021, Wiley

    Dr Francesco Tadini-Buoninsegni

  8. Protein Adsorption on Solid Supported Membranes: Monitoring the Transport Activity of P-Type ATPases

    Article • Molecules, September 2020, MDPI AG

    Dr Francesco Tadini-Buoninsegni

  9. Label-Free Bioelectrochemical Methods for Evaluation of Anticancer Drug Effects at a Molecular Level

    Article • Sensors, March 2020, MDPI AG

    Dr Francesco Tadini-Buoninsegni

  10. Niosomal Formulation of a Lipoyl-Carnosine Derivative Targeting TRPA1 Channels in Brain

    Article • Pharmaceutics, December 2019, MDPI AG

    Dr Francesco Tadini-Buoninsegni

  11. Superparamagnetic iron oxide nanoparticles (SPIONs) modulate hERG ion channel activity

    Article • Nanotoxicology, August 2019, Taylor & Francis

    Dr Francesco Tadini-Buoninsegni, Roberta Gualdani

  12. Phosphatidylserine flipping by the P4-ATPase ATP8A2 is electrogenic

    Article • Proceedings of the National Academy of Sciences, August 2019, Proceedings of the National Academy of Sciences

    Dr Francesco Tadini-Buoninsegni

  13. A Comparative Study of Phosphatidylcholine versus Phosphatidylserine-Based Solid Supported Membranes for the Preparation of Liposome-Rich Interfaces

    Article • Langmuir, September 2018, American Chemical Society (ACS)

    Dr Francesco Tadini-Buoninsegni

  14. Drug Interactions With the Ca2+-ATPase From Sarco(Endo)Plasmic Reticulum (SERCA)

    Article • Frontiers in Molecular Biosciences, April 2018, Frontiers

    Dr Francesco Tadini-Buoninsegni

  15. Selectivity of the phospholamban ion channel investigated by single channel measurements

    Article • Journal of Electroanalytical Chemistry, March 2018, Elsevier

    Dr Francesco Tadini-Buoninsegni

  16. Monitoring Interactions Inside Cells by Advanced Spectroscopies: Overview of Copper Transporters and Cisplatin

    Article • Current Medicinal Chemistry, February 2018, Bentham Science Publishers

    Dr Francesco Tadini-Buoninsegni

  17. Molecular Insights into hERG Potassium Channel Blockade by Lubeluzole

    Article • Cellular Physiology and Biochemistry, January 2018, Karger Publishers

    Dr Francesco Tadini-Buoninsegni, Giovanni Lentini

  18. Conformational memory in the association of the transmembrane protein phospholamban with the sarcoplasmic reticulum calcium pump SERCA

    Article • Journal of Biological Chemistry, October 2017, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Francesco Tadini-Buoninsegni

  19. Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX)

    Article • Journal of Medicinal Chemistry, October 2017, American Chemical Society (ACS)

    Dr Francesco Tadini-Buoninsegni

  20. Discovery of a new mexiletine-derived agonist of the hERG K + channel

    Article • Biophysical Chemistry, October 2017, Elsevier

    Giovanni Lentini, Dr Francesco Tadini-Buoninsegni

  21. Mechanisms of charge transfer in human copper ATPases ATP7A and ATP7B

    Article • IUBMB Life, February 2017, Wiley

    Dr Francesco Tadini-Buoninsegni

  22. Effect of cisplatin on the transport activity of PII-type ATPases

    Article • Metallomics, January 2017, Oxford University Press (OUP)

    Dr Francesco Tadini-Buoninsegni

  23. Global Analysis of Type Three Secretion System and Quorum Sensing Inhibition of Pseudomonas savastanoi by Polyphenols Extracts from Vegetable Residues

    Article • PLOS One, September 2016, PLOS

    Dr Francesco Tadini-Buoninsegni

  24. Phospholamban spontaneously reconstitutes into giant unilamellar vesicles where it generates a cation selective channel

    Article • Physical Chemistry Chemical Physics, January 2016, Royal Society of Chemistry

    Dr Francesco Tadini-Buoninsegni

  25. Antimony-Phosphomolybdate ATPase Assay

    Article • January 2016, Springer Science + Business Media

    Dr Francesco Tadini-Buoninsegni

  26. Electrophysiological Measurements on Solid Supported Membranes

    Article • January 2016, Springer Science + Business Media

    Dr Francesco Tadini-Buoninsegni

  27. Hofmeister effect of anions on calcium translocation by sarcoplasmic reticulum Ca2+-ATPase

    Article • Scientific Reports, October 2015, Nature

    Dr Francesco Tadini-Buoninsegni

  28. Recording of Pump and Transporter Activity Using Solid-Supported Membranes (SSM-Based Electrophysiology)

    Article • September 2015, Wiley

    Dr Francesco Tadini-Buoninsegni

  29. Inhibition of hERG potassium channel by the antiarrhythmic agent mexiletine and its metabolite m-hydroxymexiletine

    Article • Pharmacology Research & Perspectives, July 2015, Wiley

    Dr Francesco Tadini-Buoninsegni, Giovanni Lentini

  30. A sulfur-based transport pathway in Cu+-ATPases

    Article • EMBO Reports, May 2015, EMBO

    Dr Francesco Tadini-Buoninsegni

  31. Insights on Molecular Determinants of hERG K+ Channel Inhibition: Design, Synthesis, and Biological Evaluation of Lubeluzole Derivatives

    Article • Biophysical Journal, January 2015, Elsevier

    Dr Francesco Tadini-Buoninsegni

  32. Biochemical characterization of P-type copper ATPases

    Article • Biochemical Journal, October 2014, Portland Press Ltd.

    Dr Francesco Tadini-Buoninsegni

  33. Binding of a Monoclonal Antibody to the Phospholamban Cytoplasmic Domain Interferes with the Channel Activity of Phospholamban Reconstituted in a Tethered Bilayer Lipid Membrane

    Article • Langmuir, September 2014, American Chemical Society (ACS)

    Dr Francesco Tadini-Buoninsegni

  34. Anticancer Ruthenium(III) Complex KP1019 Interferes with ATP-Dependent Ca2+Translocation by Sarco-Endoplasmic Reticulum Ca2+-ATPase (SERCA)

    Article • ChemMedChem, June 2014, Wiley

    Dr Francesco Tadini-Buoninsegni

  35. Translocation of Platinum Anticancer Drugs by Human Copper ATPases ATP7A and ATP7B

    Article • Angewandte Chemie, December 2013, Wiley

    Dr Francesco Tadini-Buoninsegni

  36. Translocation of Platinum Anticancer Drugs by Human Copper ATPases ATP7A and ATP7B

    Article • Angewandte Chemie, December 2013, Wiley

    Dr Francesco Tadini-Buoninsegni

  37. Ca2+/H+ exchange, lumenal Ca2+ release and Ca2+/ATP coupling ratios in the sarcoplasmic reticulum ATPase

    Article • Journal of Cell Communication and Signaling, December 2013, Springer Science + Business Media

    Dr Francesco Tadini-Buoninsegni

  38. Enhanced Adsorption of Ca-ATPase Containing Vesicles on a Negatively Charged Solid-Supported-Membrane for the Investigation of Membrane Transporters

    Article • Langmuir, November 2013, American Chemical Society (ACS)

    Dr Francesco Tadini-Buoninsegni

  39. Istaroxime stimulates SERCA2a and accelerates calcium cycling in heart failure by relieving phospholamban inhibition

    Article • British Journal of Pharmacology, July 2013, Wiley

    Dr Francesco Tadini-Buoninsegni

  40. A Method to Measure Hydrolytic Activity of Adenosinetriphosphatases (ATPases)

    Article • PLOS One, March 2013, PLOS

    Dr Francesco Tadini-Buoninsegni

  41. Mimicking the Intramolecular Hydrogen Bond: Synthesis, Biological Evaluation, and Molecular Modeling of Benzoxazines and Quinazolines as Potential Antimalarial Agents

    Article • Journal of Medicinal Chemistry, December 2012, American Chemical Society (ACS)

    Dr sandra gemma, Dr Simone Brogi, Dr Stefania Butini, Dr Francesco Tadini-Buoninsegni

  42. Distinctive Features of Catalytic and Transport Mechanisms in Mammalian Sarco-endoplasmic Reticulum Ca2+ ATPase (SERCA) and Cu+ (ATP7A/B) ATPases

    Article • Journal of Biological Chemistry, August 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Francesco Tadini-Buoninsegni

  43. The Ca2+-ATPase (SERCA1) Is Inhibited by 4-Aminoquinoline Derivatives through Interference with Catalytic Activation by Ca2+, Whereas the ATPase E2 State Remains Functional

    Article • Journal of Biological Chemistry, September 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Francesco Tadini-Buoninsegni, Dr sandra gemma, Dr Stefania Butini

  44. The Sodium Pump is Confined in a Phosphoenzyme Form by Lead(II) Ions

    Article • Biophysical Journal, February 2011, Elsevier

    Dr Francesco Tadini-Buoninsegni

  45. Charge Movement in Recombinant Copper ATPase is Investigated on a Solid Supported Membrane

    Article • Biophysical Journal, February 2011, Elsevier

    Dr Francesco Tadini-Buoninsegni

  46. ATP dependent charge movement in ATP7B Cu+-ATPase is demonstrated by pre-steady state electrical measurements

    Article • FEBS Letters, October 2010, Wiley

    Dr Francesco Tadini-Buoninsegni

  47. Confining the Sodium Pump in a Phosphoenzyme Form: The Effect of Lead(II) Ions

    Article • Biophysical Journal, October 2010, Elsevier

    Dr Francesco Tadini-Buoninsegni

  48. Inhibition of SERCA1 by a Novel Antimalarial Compound

    Article • Biophysical Journal, January 2010, Elsevier

    Dr sandra gemma, Dr Stefania Butini, Dr Francesco Tadini-Buoninsegni

  49. Inhibitory Effect of Pb 2+ on the Transport Cycle of the Na + ,K + -ATPase

    Article • Chemical Research in Toxicology, October 2009, American Chemical Society (ACS)

    Dr Francesco Tadini-Buoninsegni

  50. Electrogenic Ion Pumps Investigated on a Solid Supported Membrane: Comparison of Current and Voltage Measurements

    Article • Langmuir, September 2009, American Chemical Society (ACS)

    Dr Francesco Tadini-Buoninsegni

  51. High-yield Heterologous Expression of Wild Type and Mutant Ca2+ ATPase: Characterization of Ca2+ Binding Sites by Charge Transfer

    Article • Journal of Molecular Biology, September 2009, Elsevier

    Dr Francesco Tadini-Buoninsegni

  52. Charge transfer in P-type ATPases investigated on planar membranes

    Article • Archives of Biochemistry and Biophysics, August 2008, Elsevier

    Dr Francesco Tadini-Buoninsegni

  53. Effect of Clotrimazole on the Pump Cycle of the Na,K-ATPase

    Article • Biophysical Journal, August 2008, Elsevier

    Dr Francesco Tadini-Buoninsegni

  54. Electrogenic steps of the SR Ca-ATPase enzymatic cycle and the effect of curcumin

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, February 2008, Elsevier

    Dr Francesco Tadini-Buoninsegni

  55. Effects of High-Affinity Inhibitors on Partial Reactions, Charge Movements, and Conformational States of the Ca2+ Transport ATPase (Sarco-Endoplasmic Reticulum Ca2+ ATPase)

    Article • Molecular Pharmacology, January 2008, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Francesco Tadini-Buoninsegni

  56. Pre-steady State Electrogenic Events of Ca2+/H+ Exchange and Transport by the Ca2+-ATPase

    Article • Journal of Biological Chemistry, October 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Francesco Tadini-Buoninsegni

  57. Clotrimazole Inhibits the Ca2+-ATPase (SERCA) by Interfering with Ca2+ Binding and Favoring the E2 Conformation

    Article • Journal of Biological Chemistry, February 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Francesco Tadini-Buoninsegni

  58. Photoinduced Electroreduction of Chlorophyllide on Alkanethiol-Coated Mercury

    Article • Journal of the American Chemical Society, February 2005, American Chemical Society (ACS)

    Dr Francesco Tadini-Buoninsegni

  59. Time-Resolved Charge Translocation by Sarcoplasmic Reticulum Ca-ATPase Measured on a Solid Supported Membrane

    Article • Biophysical Journal, June 2004, Elsevier

    Dr Francesco Tadini-Buoninsegni

  60. Calcium transport by sarcoplasmic reticulum Ca-ATPase can be investigated on a solid-supported membrane

    Article • Bioelectrochemistry, June 2004, Elsevier

    Dr Francesco Tadini-Buoninsegni

  61. Two Photobioelectrochemical Applications of Self-Assembled Films on Mercury

    Article • Collection of Czechoslovak Chemical Communications, January 2004, Institute of Organic Chemistry & Biochemistry

    Dr Francesco Tadini-Buoninsegni

  62. Electrochemical and photoelectrochemical behavior of chlorophyll a films adsorbed on mercury

    Article • Journal of Electroanalytical Chemistry, July 2003, Elsevier

    Dr Francesco Tadini-Buoninsegni

  63. Investigation of Na+,K+-ATPase on a solid supported membrane: the role of acylphosphatase on the ion transport mechanism

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, April 2003, Elsevier

    Dr Francesco Tadini-Buoninsegni, Chiara Nediani

  64. Some bioelectrochemical applications of self-assembled films on mercury

    Article • Solid State Ionics, September 2002, Elsevier

    Dr Francesco Tadini-Buoninsegni

  65. Photocurrents Generated by Bacteriorhodopsin Adsorbed on Thiol/Lipid Bilayers Supported by Mercury

    Article • Langmuir, August 2002, American Chemical Society (ACS)

    Dr Francesco Tadini-Buoninsegni

  66. Monolayers and multilayers of chlorophyl a on a mercury electrode

    Article • Bioelectrochemistry, May 2002, Elsevier

    Dr Francesco Tadini-Buoninsegni

  67. DC photoelectric signals from bacteriorhodopsin adsorbed on lipid monolayers and thiol/lipid bilayers supported by mercury

    Article • Bioelectrochemistry, May 2002, Elsevier

    Dr Francesco Tadini-Buoninsegni

  68. Bioelectrochemistry at metal∣water interfaces

    Article • Journal of Electroanalytical Chemistry, May 2001, Elsevier

    Dr Francesco Tadini-Buoninsegni

  69. Total and free charge densities on mercury coated with self-assembled phosphatidylcholine and octadecanethiol monolayers and octadecanethiol/phosphatidylcholine bilayers

    Article • Journal of Electroanalytical Chemistry, March 2001, Elsevier

    Dr Francesco Tadini-Buoninsegni

  70. A voltammetric study of monolayers and bilayers self-assembled on metal electrodes

    Article • Electrochimica Acta, February 2000, Elsevier

    Dr Francesco Tadini-Buoninsegni

  71. Bacteriorhodopsin-containing membrane fragments adsorbed on mercury-supported biomimetic membranes

    Article • Electrochemistry Communications, March 1999, Elsevier

    Dr Francesco Tadini-Buoninsegni

  72. Alkanethiol monolayers and alkanethiol|phospholipid bilayers supported by mercury: an electrochemical characterization

    Article • Journal of Electroanalytical Chemistry, July 1998, Elsevier

    Dr Francesco Tadini-Buoninsegni

  73. Surface Dipole Potential at the Interface between Water and Self-Assembled Monolayers of Phosphatidylserine and Phosphatidic Acid

    Article • Biophysical Journal, May 1998, Elsevier

    Dr Francesco Tadini-Buoninsegni

  74. Electron and proton transferring properties of vitamin K1 across a self-assembled phospholipid monolayer

    Article • Journal of Electroanalytical Chemistry, March 1998, Elsevier

    Dr Francesco Tadini-Buoninsegni