All Stories

  1. Nav1.8: Intrinsic limits on the functional effect of abrogation in DRG neurons

    Article • Proceedings of the National Academy of Sciences, September 2025, Proceedings of the National Academy of Sciences

    Roberta Gualdani

  2. Nav1.8, an analgesic target for nonpsychotomimetic phytocannabinoids

    Article • Proceedings of the National Academy of Sciences, January 2025, Proceedings of the National Academy of Sciences

    Roberta Gualdani

  3. TRPV1 corneal neuralgia mutation: Enhanced pH response, bradykinin sensitization, and capsaicin desensitization

    Article • Proceedings of the National Academy of Sciences, September 2024, Proceedings of the National Academy of Sciences

    Roberta Gualdani

  4. Inflammation differentially controls transport of depolarizing Nav versus hyperpolarizing Kv channels to drive rat nociceptor activity

    Article • Proceedings of the National Academy of Sciences, March 2023, Proceedings of the National Academy of Sciences

    Roberta Gualdani

  5. A mutation of the TRPM7 channel provides new insights into familial Trigeminal Neuralgia

    Article • Proceedings of the National Academy of Sciences, September 2022, Proceedings of the National Academy of Sciences

    Roberta Gualdani

  6. Superparamagnetic iron oxide nanoparticles (SPIONs) modulate hERG ion channel activity

    Article • Nanotoxicology, August 2019, Taylor & Francis

    Dr Francesco Tadini-Buoninsegni, Roberta Gualdani

  7. A gain-of-function sodium channelβ2-subunit mutation in painful diabetic neuropathy

    Article • Molecular Pain, January 2019, SAGE Publications

    Roberta Gualdani, Massimo Mantegazza

  8. A novel gain-of-function Nav1.7 mutation in a carbamazepine-responsive patient with adult-onset painful peripheral neuropathy

    Article • Molecular Pain, January 2018, SAGE Publications

    Roberta Gualdani

  9. Reverse pharmacogenomics: carbamazepine normalizes activation and attenuates thermal hyperexcitability of sensory neurons due to Nav 1.7 mutation I234T

    Article • British Journal of Pharmacology, July 2017, Wiley

    Sulayman Dib-Hajj, Roberta Gualdani

  10. A SCN10A SNP biases human pain sensitivity

    Article • Molecular Pain, January 2016, SAGE Publications

    Roberta Gualdani

  11. A painful neuropathy-associated Nav1.7 mutant leads to time-dependent degeneration of small-diameter axons associated with intracellular Ca2+ dysregulation and decrease in ATP levels

    Article • Molecular Pain, January 2016, SAGE Publications

    Roberta Gualdani