All Stories

  1. Inflammation differentially controls transport of depolarizing Nav versus hyperpolarizing Kv channels to drive rat nociceptor activity

    Article • Proceedings of the National Academy of Sciences, March 2023, Proceedings of the National Academy of Sciences

    Roberta Gualdani

  2. A mutation of the TRPM7 channel provides new insights into familial Trigeminal Neuralgia

    Article • Proceedings of the National Academy of Sciences, September 2022, Proceedings of the National Academy of Sciences

    Roberta Gualdani

  3. Superparamagnetic iron oxide nanoparticles (SPIONs) modulate hERG ion channel activity

    Article • Nanotoxicology, August 2019, Taylor & Francis

    Dr Francesco Tadini Buoninsegni, Roberta Gualdani

  4. A gain-of-function sodium channelβ2-subunit mutation in painful diabetic neuropathy

    Article • Molecular Pain, January 2019, SAGE Publications

    Roberta Gualdani

  5. A novel gain-of-function Nav1.7 mutation in a carbamazepine-responsive patient with adult-onset painful peripheral neuropathy

    Article • Molecular Pain, January 2018, SAGE Publications

    Roberta Gualdani

  6. Reverse pharmacogenomics: carbamazepine normalizes activation and attenuates thermal hyperexcitability of sensory neurons due to Nav 1.7 mutation I234T

    Article • British Journal of Pharmacology, July 2017, Wiley

    Sulayman Dib-Hajj, Roberta Gualdani

  7. A SCN10A SNP biases human pain sensitivity

    Article • Molecular Pain, January 2016, SAGE Publications

    Roberta Gualdani

  8. A painful neuropathy-associated Nav1.7 mutant leads to time-dependent degeneration of small-diameter axons associated with intracellular Ca2+ dysregulation and decrease in ATP levels

    Article • Molecular Pain, January 2016, SAGE Publications

    Roberta Gualdani