All Stories

  1. Anoikis Resistance as a Further Trait of Acidic-Adapted Melanoma Cells

    Article • Journal of Oncology, June 2019, Hindawi Publishing Corporation

    Elena Andreucci, Chiara Nediani, Silvia Peppicelli

  2. Oleuropein, the Main Polyphenol of Olea europaea Leaf Extract, Has an Anti-Cancer Effect on Human BRAF Melanoma Cells and Potentiates the Cytotoxicity of Current Chemotherapies

    Article • Nutrients, December 2018, MDPI AG

    Chiara Nediani, Elena Andreucci

  3. Oleuropein, the Main Polyphenol of Olea europaea Leaf Extract, Has an Anti Cancer Effect on Human BRAF Melanoma Cells and Potentiates the Cytotoxicity of Current Chemotherapies

    Article • November 2018, MDPI AG

    Chiara Nediani

  4. Biochemical aspects and molecular mechanisms induced by oleuropein on cardiomyocytes

    Article • Oxidative Medicine and Cellular Longevity, January 2018, Hindawi Publishing Corporation

    Chiara Nediani

  5. The Polyphenol Oleuropein Aglycone Modulates the PARP1-SIRT1 Interplay: An In Vitro and In Vivo Study

    Article • Journal of Alzheimer s Disease, September 2016, IOS Press

    Chiara Nediani

  6. Impaired mitochondrial biogenesis is a common feature to myocardial hypertrophy and end-stage ischemic heart failure

    Article • Cardiovascular Pathology, March 2016, Elsevier

    Chiara Nediani

  7. Monoamine Oxidase Is Overactivated in Left and Right Ventricles from Ischemic Hearts: An Intriguing Therapeutic Target

    Article • Oxidative Medicine and Cellular Longevity, January 2016, Hindawi Publishing Corporation

    Chiara Nediani

  8. Oleuropein aglycone induces autophagy via the AMPK/mTOR signalling pathway: a mechanistic insight

    Article • Oncotarget, October 2015, Impact Journals, LLC

    Chiara Nediani

  9. Mild exposure of RIN-5F β-cells to human islet amyloid polypeptide aggregates upregulates antioxidant enzymes via NADPH oxidase-RAGE: An hormetic stimulus

    Article • Redox Biology, January 2014, Elsevier

    Chiara Nediani

  10. p53-PGC-1α Pathway Mediates Oxidative Mitochondrial Damage and Cardiomyocyte Necrosis Induced by Monoamine Oxidase-A Upregulation: Role in Chronic Left Ventricular Dysfunction in Mice

    Article • Antioxidants and Redox Signaling, January 2013, Mary Ann Liebert Inc

    Dr Pierre Sicard, Chiara Nediani

  11. Nitric Oxide/Reactive Oxygen Species Generation and Nitroso/Redox Imbalance in Heart Failure: From Molecular Mechanisms to Therapeutic Implications

    Article • Antioxidants and Redox Signaling, January 2011, Mary Ann Liebert Inc

    Chiara Nediani

  12. Oleuropein aglycon prevents cytotoxic amyloid aggregation of human amylin☆

    Article • The Journal of Nutritional Biochemistry, August 2010, Elsevier

    Chiara Nediani

  13. Enhanced ROS production by NADPH oxidase is correlated to changes in antioxidant enzyme activity in human heart failure

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, March 2010, Elsevier

    Chiara Nediani

  14. Functional coupling of angiotensin II type 1 receptor with insulin resistance of energy substrate uptakes in immortalized cardiomyocytes (HL-1 cells)

    Article • British Journal of Pharmacology, January 2009, Wiley

    Chiara Nediani

  15. Role of NADPH oxidase in H9c2 cardiac muscle cells exposed to simulated ischaemia‐reperfusion

    Article • Journal of Cellular and Molecular Medicine, August 2008, Wiley

    Chiara Nediani

  16. Induction of Mitochondrial Biogenesis Is a Maladaptive Mechanism in Mitochondrial Cardiomyopathies

    Article • Journal of the American College of Cardiology, October 2007, Elsevier

    Chiara Nediani

  17. NADPH oxidase-dependent redox signaling in human heart failure: Relationship between the left and right ventricle

    Article • Journal of Molecular and Cellular Cardiology, April 2007, Elsevier

    Chiara Nediani

  18. Cardiac volume overload rapidly induces oxidative stress-mediated myocyte apoptosis and hypertrophy

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, June 2005, Elsevier

    Chiara Nediani

  19. Possible role of acylphosphatase, Bcl-2 and Fas/Fas-L system in the early changes of cardiac remodeling induced by volume overload

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, July 2003, Elsevier

    Chiara Nediani

  20. Investigation of Na+,K+-ATPase on a solid supported membrane: the role of acylphosphatase on the ion transport mechanism

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, April 2003, Elsevier

    Dr Francesco Tadini Buoninsegni, Chiara Nediani

  21. Acylphosphatase interferes with SERCA2a–PLN association

    Article • Biochemical and Biophysical Research Communications, February 2003, Elsevier

    Chiara Nediani

  22. Beneficial Effects of Poly (ADP-ribose) Polymerase Inhibition Against the Reperfusion Injury in Heart Transplantation

    Article • Free Radical Research, January 2003, Taylor & Francis

    Chiara Nediani

  23. Biochemical changes and their relationship with morphological and functional findings in pig heart subjected to lasting volume overload: a possible role of acylphosphatase in the regulation of sarcoplasmic reticulum calcium pump

    Article • Basic Research in Cardiology, October 2002, Springer Science + Business Media

    Chiara Nediani

  24. Poly(ADP-ribose) Polymerase Activation and Cell Injury in the Course of Rat Heart Heterotopic Transplantation

    Article • Free Radical Research, January 2002, Taylor & Francis

    Chiara Nediani

  25. Are macrophages involved in early myocardial reperfusion injury?

    Article • The Annals of Thoracic Surgery, May 2001, Elsevier

    Chiara Nediani

  26. Early Changes Induced in the Left Ventricle by Pressure Overload. An Experimental Study on Swine Heart

    Article • Journal of Molecular and Cellular Cardiology, January 2000, Elsevier

    Chiara Nediani

  27. Transcriptional Down-regulation of Poly(ADP-ribose) Polymerase Gene Expression by E1A Binding to pRb Proteins Protects Murine Keratinocytes from Radiation-induced Apoptosis

    Article • Journal of Biological Chemistry, December 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Chiara Nediani

  28. A novel interaction mechanism accounting for different acylphosphatase effects on cardiac and fast twitch skeletal muscle sarcoplasmic reticulum calcium pumps

    Article • FEBS Letters, January 1999, Wiley

    Chiara Nediani

  29. Ischemia–Reperfusion-Induced Apoptosis and p53 Expression in the Course of Rat Heterotopic Heart Transplantation

    Article • Microvascular Research, November 1998, Elsevier

    Chiara Nediani

  30. Oxidative Stress and Antioxidant Defenses in Renal Patients Receiving Regular Haemodialysis

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 1998, De Gruyter

    Chiara Nediani

  31. Beneficial Effects of the 21-Aminosteroid U 74389G on the Ischemia-reperfusion Damage in Pig Hearts

    Article • Journal of Molecular and Cellular Cardiology, October 1997, Elsevier

    Chiara Nediani

  32. Stimulation of Cardiac Sarcoplasmic Reticulum Calcium Pump by Acylphosphatase

    Article • Journal of Biological Chemistry, August 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

    Chiara Nediani

  33. PROTECTION OF RAT HEART FROM ISCHAEMIA-REPERFUSION INJURY BY THE 21-AMINOSTEROID U-74389G

    Article • Pharmacological Research, July 1996, Elsevier

    Professor Massimo Bonacchi, Chiara Nediani

  34. Acylphosphatase: A Potential Modulator of Heart Sarcolemma Na+,K+ Pump

    Article • Biochemistry, May 1995, American Chemical Society (ACS)

    Chiara Nediani

  35. Modifications induced by acylphosphatase in the functional properties of heart sarcolemma Na+ , K+ pump

    Article • FEBS Letters, March 1994, Wiley

    Chiara Nediani

  36. Modifications induced by acylphosphatase in the functional properties of heart sarcolemma Na+ ,K+ pump

    Article • FEBS Letters, January 1994, Wiley

    Chiara Nediani

  37. Acylphosphatase induced modifications in the functional properties of erythrocyte membrane sodium pump

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, April 1993, Elsevier

    Chiara Nediani

  38. Isolation and quantitation of ubiquitin from rat brain

    Article • Protein Expression and Purification, September 1990, Elsevier

    Chiara Nediani

  39. Changes in Na+,K+-ATPase, Ca2+-ATPase and some soluble enzymes related to energy metabolism in brains of patients with Alzheimer's disease

    Article • Neuroscience Letters, May 1990, Elsevier

    Chiara Nediani

  40. Effect of acylphosphatase on human erythrocyte membrane Ca2+-ATPase

    Article • Biochemical and Biophysical Research Communications, April 1990, Elsevier

    Chiara Nediani

  41. Increased Acylphosphatase Levels in Erythrocytes, Muscle and Liver of Tri-Iodothyronine Treated Rabbits

    Article • Hormone and Metabolic Research, January 1990, Thieme Publishing Group

    Chiara Nediani

  42. Increased acylphosphatase levels in erythrocytes from hyperthyroid patients

    Article • Clinica Chimica Acta, August 1989, Elsevier

    Chiara Nediani

  43. Biochemical, anatomical and functional correlates of postnatal development of the capsaicin-sensitive innervation of the rat urinary bladder

    Article • Developmental Brain Research, October 1988, Elsevier

    Chiara Nediani

  44. Post-mortem modifications of the specific activity of some brain enzymes

    Article • Neuroscience Letters, February 1988, Elsevier

    Chiara Nediani

  45. Acylphosphatase levels of human erythrocytes during cell ageing

    Article • Mechanisms of Ageing and Development, June 1987, Elsevier

    Chiara Nediani